Novel compositions and methods for cancer

ABSTRACT

The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially lymphoma carcinomas. In addition, the present invention describes the use of novel compositions for use in screening methods.

[0001] The present application is a continuing application of U.S. Ser. Nos. 09/747,377, filed Dec. 22, 2000 and 09/798,586. filed Mar. 2, 2001, both of which are expressly incorporated herein by reference.

FIELD OF THE INVENTION

[0002] The present invention relates to novel sequences for use in diagnosis and treatment of cancer, especially carcinomas, as well as the use of the novel compositions in screening methods.

BACKGROUND OF THE INVENTION

[0003] Oncogenes are genes that can cause cancer. Carcinogenesis can occur by a wide variety of mechanisms, including infection of cells by viruses containing oncogenes, activation of protooncogenes in the host genome, and mutations of protooncogenes and tumor suppressor genes.

[0004] There are a number of viruses known to be involved in human cancer as well as in animal cancer. Of particular interest here are viruses that do not contain oncogenes themselves; these are slow-transforming retroviruses. They induce tumors by integrating into the host genome and affecting neighboring protooncogenes in a variety of ways, including promoter insertion, enhancer insertion, and/or truncation of a protooncogene or tumor suppressor gene. The analysis of sequences at or near the insertion sites led to the identification of a number of new protooncogenes.

[0005] With respect to lymphoma and leukemia, murine leukemia retrovirus (MuLV), such as SL3-3 or Akv, is a potent inducer of tumors when inoculated into susceptible newborn mice, or when carried in the germline. A number of sequences have been identified as relevant in the induction of lymphoma and leukemia by analyzing the insertion sites; see Sorensen et al., J. of Virology 74:2161 (2000); Hansen et al., Genome Res. 10(2):237-43 (2000); Sorensen et al., J. Virology 70:4063 (1996); Sorensen et al., J. Virology 67:7118 (1993); Joosten et al., Virology 268:308 (2000); and Li et al., Nature Genetics 23:348 (1999); all of which are expressly incorporated by reference herein.

[0006] Accordingly, it is an object of the invention to provide sequences involved in cancer and in particular in oncogenesis.

SUMMARY OF THE INVENTION

[0007] In accordance with the objects outlined above, the present invention provides methods for screening for compositions which modulate carcinomas, especially lymphoma and leukemia. Also provided herein are methods of inhibiting proliferation of a cell, preferably a lymphoma cell. Methods of treatment of carcinomas, including diagnosis, are also provided herein.

[0008] In one aspect, a method of screening drug candidates comprises providing a cell that expresses a carcinoma associated (CA) gene or fragments thereof. Preferred embodiments of CA genes are genes which are differentially expressed in cancer cells, preferably lymphatic, breast, prostate or epithelial cells, compared to other cells. Preferred embodiments of CA genes used in the methods herein include, but are not limited to the nucleic acids selected from Tables 1-10. The method further includes adding a drug candidate to the cell and determining the effect of the drug candidate on the expression of the CA gene.

[0009] In one embodiment, the method of screening drug candidates includes comparing the level of expression in the absence of the drug candidate to the level of expression in the presence of the drug candidate.

[0010] Also provided herein is a method of screening for a bioactive agent capable of binding to a CA protein (CAP), the method comprising combining the CAP and a candidate bioactive agent, and determining the binding of the candidate agent to the CAP.

[0011] Further provided herein is a method for screening for a bioactive agent capable of modulating the activity of a CAP. In one embodiment, the method comprises combining the CAP and a candidate bioactive agent, and determining the effect of the candidate agent on the bioactivity of the CAP.

[0012] Also provided is a method of evaluating the effect of a candidate carcinoma drug comprising administering the drug to a patient and removing a cell sample from the patient. The expression profile of the cell is then determined. This method may further comprise comparing the expression profile of the patient to an expression profile of a heathy individual.

[0013] In a further aspect, a method for inhibiting the activity of an CA protein is provided. In one embodiment, the method comprises administering to a patient an inhibitor of a CA protein preferably selected from the group consisting of the sequences outlined in Tables 1-10 or their complements.

[0014] A method of neutralizing the effect of a CA protein, preferably a protein encoded by a nucleic acid selected from the group of sequences outlined in Tables 1-10, is also provided. Preferably, the method comprises contacting an agent specific for said protein with said protein in an amount sufficient to effect neutralization.

[0015] Moreover, provided herein is a biochip comprising a nucleic acid segment which encodes a CA protein, preferably selected from the sequences outlined in Tables 1-10.

[0016] Also provided herein is a method for diagnosing or determining the propensity to carcinomas, especially lymphoma or leukemia by sequencing at least one carcinoma or lymphoma gene of an individual. In yet another aspect of the invention, a method is provided for determining carcinoma including lymphoma and leukemia gene copy number in an individual.

[0017] Novel sequences are also provided herein. Other aspects of the invention will become apparent to the skilled artisan by the following description of the invention.

DETAILED DESCRIPTION OF THE INVENTION

[0018] The present invention is directed to a number of sequences associated with carcinomas, especially lymphoma, breast cancer or prostate cancer. The relatively tight linkage between clonally-integrated proviruses and protooncogenes forms “provirus tagging”, in which slow-transforming retroviruses that act by an insertion mutation mechanism are used to isolate protooncogenes. In some models, uninfected animals have low cancer rates, and infected animals have high cancer rates. It is known that many of the retroviruses involved do not carry transduced host protooncogenes or pathogenic trans-acting viral genes, and thus the cancer incidence must therefor be a direct consequence of proviral integration effects into host protooncogenes. Since proviral integration is random, rare integrants will “activate” host protooncogenes that provide a selective growth advantage, and these rare events result in new proviruses at clonal stoichiometries in tumors.

[0019] The use of oncogenic retroviruses, whose sequences insert into the genome of the host organism resulting in carcinoma, allows the identification of host sequences involved in carcinoma. These sequences may then be used in a number of different ways, including diagnosis, prognosis, screening for modulators (including both agonists and antagonists), antibody generation (for immunotherapy and imaging), etc. However, as will be appreciated by those in the art, oncogenes that are identified in one type of cancer such as lymphoma or leukemia have a strong likelihood of being involved in other types of cancers as well. Thus, while the sequences outlined herein are initially identified as correlated with lymphoma, they can also be found in other types of cancers as well, outlined below.

[0020] Accordingly, the present invention provides nucleic acid and protein sequences that are associated with carcinoma, herein termed “carcinoma associated” or “CA” sequences. In a preferred embodiment, the present invention provides nucleic acid and protein sequences that are associated with carcinomas which originate in lymphatic tissue, herein termed “lymphoma associated”, “leukemia associated” or “LA” sequences.

[0021] Suitable cancers which can be diagnosed or screened for using the methods of the present invention include cancers classified by site or by histological type. Cancers classified by site include cancer of the oral cavity and pharynx (lip, tongue, salivary gland, floor of mouth, gum and other mouth, nasopharynx, tonsil, oropharynx, hypopharynx, other oral/pharynx); cancers of the digestive system (esophagus; stomach; small intestine; colon and rectum; anus, anal canal, and anorectum; liver; intrahepatic bile duct; gallbladder; other biliary; pancreas; retroperitoneum; peritoneum, omentum, and mesentery; other digestive); cancers of the respiratory system (nasal cavity, middle ear, and sinuses; larynx; lung and bronchus; pleura; trachea, mediastinum, and other respiratory); cancers of the mesothelioma; bones and joints; and soft tissue, including heart; skin cancers, including melanomas and other non-epithelial skin cancers; Kaposi's sarcoma and breast cancer; cancer of the female genital system (cervix uteri; corpus uteri; uterus, nos; ovary; vagina; vulva; and other female genital); cancers of the male genital system (prostate gland; testis; penis; and other male genital); cancers of the urinary system (urinary bladder; kidney and renal pelvis; ureter; and other urinary); cancers of the eye and orbit; cancers of the brain and nervous system (brain; and other nervous system); cancers of the endocrine system (thyroid gland and other endocrine, including thymus); cancers of the lymphomas (hodgkin's disease and non-hodgkin's lymphoma), multiple myeloma, and leukemias (lymphocytic leukemia; myeloid leukemia; monocytic leukemia; and other leukemias).

[0022] Other cancers, classified by histological type, that may be associated with the sequences of the invention include, but are not limited to, Neoplasm, malignant; Carcinoma, NOS; Carcinoma, undifferentiated, NOS; Giant and spindle cell carcinoma; Small cell carcinoma, NOS; Papillary carcinoma, NOS; Squamous cell carcinoma, NOS; Lymphoepithelial carcinoma; Basal cell carcinoma, NOS; Pilomatrix carcinoma; Transitional cell carcinoma, NOS; Papillary transitional cell carcinoma; Adenocarcinoma, NOS; Gastrinoma, malignant; Cholangiocarcinoma; Hepatocellular carcinoma, NOS; Combined hepatocellular carcinoma and cholangiocarcinoma; Trabecular adenocarcinoma; Adenoid cystic carcinoma; Adenocarcinoma in adenomatous polyp; Adenocarcinoma, familial polyposis coli; Solid carcinoma, NOS; Carcinoid tumor, malignant; Branchiolo-alveolar adenocarcinoma; Papillary adenocarcinoma, NOS; Chromophobe carcinoma; Acidophil carcinoma; Oxyphilic adenocarcinoma; Basophil carcinoma; Clear cell adenocarcinoma, NOS; Granular cell carcinoma; Follicular adenocarcinoma, NOS; Papillary and follicular adenocarcinoma; Nonencapsulating sclerosing carcinoma; Adrenal cortical carcinoma; Endometroid carcinoma; Skin appendage carcinoma; Apocrine adenocarcinoma; Sebaceous adenocarcinoma; Ceruminous adenocarcinoma; Mucoepidermoid carcinoma; Cystadenocarcinoma, NOS; Papillary cystadenocarcinoma, NOS; Papillary serous cystadenocarcinoma; Mucinous cystadenocarcinoma, NOS; Mucinous adenocarcinoma; Signet ring cell carcinoma; Infiltrating duct carcinoma; Medullary carcinoma, NOS; Lobular carcinoma; Inflammatory carcinoma; Paget”s disease, mammary; Acinar cell carcinoma; Adenosquamous carcinoma; Adenocarcinoma w/ squamous metaplasia; Thymoma, malignant; Ovarian stromal tumor, malignant; Thecoma, malignant; Granulosa cell tumor, malignant; Androblastoma, malignant; Sertoli cell carcinoma; Leydig cell tumor, malignant; Lipid cell tumor, malignant; Paraganglioma, malignant; Extra-mammary paraganglioma, malignant; Pheochromocytoma; Glomangiosarcoma; Malignant melanoma, NOS; Amelanotic melanoma; Superficial spreading melanoma; Malig melanoma in giant pigmented nevus; Epithelioid cell melanoma; Blue nevus, malignant; Sarcoma, NOS; Fibrosarcoma, NOS; Fibrous histiocytoma, malignant; Myxosarcoma; Liposarcoma, NOS; Leiomyosarcoma, NOS; Rhabdomyosarcoma, NOS; Embryonal rhabdomyosarcoma; Alveolar rhabdomyosarcoma; Stromal sarcoma, NOS; Mixed tumor, malignant, NOS; Mullerian mixed tumor; Nephroblastoma; Hepatoblastoma; Carcinosarcoma, NOS; Mesenchymoma, malignant; Brenner tumor, malignant; Phyllodes tumor, malignant; Synovial sarcoma, NOS; Mesothelioma, malignant; Dysgerminoma; Embryonal carcinoma, NOS; Teratoma, malignant, NOS; Struma ovarii, malignant; Choriocarcinoma; Mesonephroma, malignant; Hemangiosarcoma; Hemangioendothelioma, malignant; Kaposi's sarcoma; Hemangiopericytoma, malignant; Lymphangiosarcoma; Osteosarcoma, NOS; Juxtacortical osteosarcoma; Chondrosarcoma, NOS; Chondroblastoma, malignant; Mesenchymal chondrosarcoma; Giant cell tumor of bone; Ewing's sarcoma; Odontogenic tumor, malignant; Ameloblastic odontosarcoma; Ameloblastoma, malignant; Ameloblastic fibrosarcoma; Pinealoma, malignant; Chordoma; Glioma, malignant; Ependymoma, NOS; Astrocytoma, NOS; Protoplasmic astrocytoma; Fibrillary astrocytoma; Astroblastoma; Glioblastoma, NOS; Oligodendroglioma, NOS; Oligodendroblastoma; Primitive neuroectodermal; Cerebellar sarcoma, NOS; Ganglioneuroblastoma; Neuroblastoma, NOS; Retinoblastoma, NOS; Olfactory neurogenic tumor; Meningioma, malignant; Neurofibrosarcoma; Neurilemmoma, malignant; Granular cell tumor, malignant; Malignant lymphoma, NOS; Hodgkin's disease, NOS; Hodgkin's; paragranuloma, NOS; Malignant lymphoma, small lymphocytic; Malignant lymphoma, large cell, diffuse; Malignant lymphoma, follicular, NOS; Mycosis fungoides; Other specified non-Hodgkin's lymphomas; Malignant histiocytosis; Multiple myeloma; Mast cell sarcoma; Immunoproliferative small intestinal disease; Leukemia, NOS; Lymphoid leukemia, NOS; Plasma cell leukemia; Erythroleukemia; Lymphosarcoma cell leukemia; Myeloid leukemia, NOS; Basophilic leukemia; Eosinophilic leukemia; Monocytic leukemia, NOS; Mast cell leukemia; Megakaryoblastic leukemia; Myeloid sarcoma; and Hairy cell leukemia.

[0023] Association in this context means that the nucleotide or protein sequences are either differentially expressed, activated, inactivated or altered in carcinomas as compared to normal tissue. As outlined below, CA sequences include those that are up-regulated (i.e. expressed at a higher level), as well as those that are down-regulated (i.e. expressed at a lower level), in carcinomas. CA sequences also include sequences which have been altered (i.e., truncated sequences or sequences with substitutions, deletions or insertions, including point mutations) and show either the same expression profile or an altered profile. In a preferred embodiment, the CA sequences are from humans; however, as will be appreciated by those in the art, CA sequences from other organisms may be useful in animal models of disease and drug evaluation; thus, other CA sequences are provided, from vertebrates, including mammals, including rodents (rats, mice, hamsters, guinea pigs, etc.), primates, farm animals (including sheep, goats, pigs, cows, horses, etc). In some cases, prokaryotic CA sequences may be useful. CA sequences from other organisms may be obtained using the techniques outlined below.

[0024] CA sequences can include both nucleic acid and amino acid sequences. In a preferred embodiment, the CA sequences are recombinant nucleic acids. By the term “recombinant nucleic acid” herein is meant nucleic acid, originally formed in vitro, in general, by the manipulation of nucleic acid by polymerases and endonucleases, in a form not normally found in nature. Thus an isolated nucleic acid, in a linear form, or an expression vector formed in vitro by ligating DNA molecules that are not normally joined, are both considered recombinant for the purposes of this invention. It is understood that once a recombinant nucleic acid is made and reintroduced into a host cell or organism, it will replicate non-recombinantly, i.e. using the in vivo cellular machinery of the host cell rather than in vitro manipulations; however, such nucleic acids, once produced recombinantly, although subsequently replicated non-recombinantly, are still considered recombinant for the purposes of the invention.

[0025] Similarly, a “recombinant protein” is a protein made using recombinant techniques, i.e. through the expression of a recombinant nucleic acid as depicted above. A recombinant protein is distinguished from naturally occurring protein by at least one or more characteristics. For example, the protein may be isolated or purified away from some or all of the proteins and compounds with which it is normally associated in its wild type host, and thus may be substantially pure. For example, an isolated protein is unaccompanied by at least some of the material with which it is normally associated in its natural state, preferably constituting at least about 0.5%, more preferably at least about 5% by weight of the total protein in a given sample. A substantially pure protein comprises at least about 75% by weight of the total protein, with at least about 80% being preferred, and at least about 90% being particularly preferred. The definition includes the production of an CA protein from one organism in a different organism or host cell. Alternatively, the protein may be made at a significantly higher concentration than is normally seen, through the use of an inducible promoter or high expression promoter, such that the protein is made at increased concentration levels. Alternatively, the protein may be in a form not normally found in nature, as in the addition of an epitope tag or amino acid substitutions, insertions and deletions, as discussed below.

[0026] In a preferred embodiment, the CA sequences are nucleic acids. As will be appreciated by those in the art and is more fully outlined below, CA sequences are useful in a variety of applications, including diagnostic applications, which will detect naturally occurring nucleic acids, as well as screening applications; for example, biochips comprising nucleic acid probes to the CA sequences can be generated. In the broadest sense, then, by “nucleic acid” or “oligonucleotide” or grammatical equivalents herein means at least two nucleotides covalently linked together. A nucleic acid of the present invention will generally contain phosphodiester bonds, although in some cases, as outlined as below (for example in antisense applications or when a candidate agent is a nucleic acid), nucleic acid analogs may be used that have alternate backbones, comprising, for example, phosphoramidate (Beaucage et al., Tetrahedron 49(10):1925 (1993) and references therein; Letsinger, J. Org. Chem. 35:3800 (1970); Sprinzl et al., Eur. J. Biochem. 81:579 (1977); Letsinger et al., Nucl. Acids Res. 14:3487 (1986); Sawai et al, Chem. Lett. 805 (1984), Letsinger et al., J. Am. Chem. Soc. 110:4470 (1988); and Pauwels et al., Chemica Scripta 26:141 91986)), phosphorothioate (Mag et al., Nucleic Acids Res. 19:1437 (1991); and U.S. Pat. No. 5,644,048), phosphorodithioate (Briu et al., J. Am. Chem. Soc. 111:2321 (1989), O-methylphophoroamidite linkages (see Eckstein, Oligonucleotides and Analogues: A Practical Approach, Oxford University Press), and peptide nucleic acid backbones and linkages (see Egholm, J. Am. Chem. Soc. 114:1895 (1992); Meieretal., Chem. Int. Ed. Engl. 31:1008 (1992); Nielsen, Nature, 365:566 (1993); Carlsson et al., Nature 380:207 (1996), all of which are incorporated by reference). Other analog nucleic acids include those with positive backbones (Denpcy et al., Proc. Natl. Acad. Sci. USA 92:6097 (1995); non-ionic backbones (U.S. Pat. Nos. 5,386,023, 5,637,684, 5,602,240, 5,216,141 and 4,469,863; Kiedrowshi et al., Angew. Chem. Intl. Ed. English 30:423 (1991); Letsinger et al., J. Am. Chem. Soc. 110:4470 (1988); Letsinger et al., Nucleoside & Nucleotide 13:1597 (1994); Chapters 2 and 3, ASC Symposium Series 580, “Carbohydrate Modifications in Antisense Research”, Ed. Y. S. Sanghui and P. Dan Cook; Mesmaeker et al., Bioorganic & Medicinal Chem. Lett. 4:395 (1994); Jeffs et al., J. Biomolecular NMR 34:17 (1994); Tetrahedron Lett. 37:743 (1996)) and non-ribose backbones, including those described in U.S. Pat. Nos. 5,235,033 and 5,034,506, and Chapters 6 and 7, ASC Symposium Series 580, “Carbohydrate Modifications in Antisense Research”, Ed. Y. S. Sanghui and P. Dan Cook. Nucleic acids containing one or more carbocyclic sugars are also included within one definition of nucleic acids (see Jenkins et al., Chem. Soc. Rev. (1995) pp169-176). Several nucleic acid analogs are described in Rawls, C & E News Jun. 2, 1997 page 35. All of these references are hereby expressly incorporated by reference. These modifications of the ribose-phosphate backbone may be done for a variety of reasons, for example to increase the stability and half-life of such molecules in physiological environments for use in anti-sense applications or as probes on a biochip.

[0027] As will be appreciated by those in the art, all of these nucleic acid analogs may find use in the present invention. In addition, mixtures of naturally occurring nucleic acids and analogs can be made; alternatively, mixtures of different nucleic acid analogs, and mixtures of naturally occurring nucleic acids and analogs may be made.

[0028] The nucleic acids may be single stranded or double stranded, as specified, or contain portions of both double stranded or single stranded sequence. As will be appreciated by those in the art, the depiction of a single strand “Watson” also defines the sequence of the other strand “Crick”; thus the sequences described herein also includes the complement of the sequence. The nucleic acid may be DNA, both genomic and cDNA, RNA or a hybrid, where the nucleic acid contains any combination of deoxyribo- and ribo-nucleotides, and any combination of bases, including uracil, adenine, thymine, cytosine, guanine, inosine, xanthine hypoxanthine, isocytosine, isoguanine, etc. As used herein, the term “nucleoside” includes nucleotides and nucleoside and nucleotide analogs, and modified nucleosides such as amino modified nucleosides. In addition, “nucleoside” includes non-naturally occurring analog structures. Thus for example the individual units of a peptide nucleic acid, each containing a base, are referred to herein as a nucleoside.

[0029] An CA sequence can be initially identified by substantial nucleic acid and/or amino acid sequence homology to the CA sequences outlined herein. Such homology can be based upon the overall nucleic acid or amino acid sequence, and is generally determined as outlined below, using either homology programs or hybridization conditions.

[0030] The CA sequences of the invention were initially identified as described herein; basically, infection of mice with murine leukemia viruses (MLV) resulted in lymphoma, although many of these sequences will also be involved in other cancers as is generally outlined herein.

[0031] The CA sequences outlined herein comprise the insertion sites for the virus. In general, the retrovirus can cause carcinomas in three basic ways: first of all, by inserting upstream of a normally silent host gene and activating it (e.g. promoter insertion); secondly, by truncating a host gene that leads to oncogenesis; or by enhancing the transcription of a neighboring gene. For example, retrovirus enhancers, including SL3-3, are known to act on genes up to approximately 200 kilobases of the insertion site.

[0032] In a preferred embodiment, CA sequences are those that are up-regulated in carcinomas; that is, the expression of these genes is higher in carcinoma tissue as compared to normal tissue of the same differentiation stage. “Up-regulation” as used herein means at least about 50%, more preferably at least about 100%, more preferably at least about 150%, more preferably, at least about 200%, with from 300 to at least 1000% being especially preferred.

[0033] In a preferred embodiment, CA sequences are those that are down-regulated in carcinomas; that is, the expression of these genes is lower in carcinoma tissue as compared to normal I tissue of the same differentiation stage. “Down-regulation” as used herein means at least about 50%, more preferably at least about 100%, more preferably at least about 150%, more preferably, at least about 200%, with from 300 to at least 1000% being especially preferred.

[0034] In a preferred embodiment, CA sequences are those that are altered but show either the same expression profile or an altered profile as compared to normal lymphoid tissue of the same differentiation stage. “Altered CA sequences” as used herein refers to sequences which are truncated, contain insertions or contain point mutations.

[0035] CA proteins of the present invention may be classified as secreted proteins, transmembrane proteins or intracellular proteins.

[0036] In a preferred embodiment the CA protein is an intracellular protein. Intracellular proteins may be found in the cytoplasm and/or in the nucleus. Intracellular proteins are involved in all aspects of cellular function and replication (including, for example, signaling pathways); aberrant expression of such proteins results in unregulated or disregulated cellular processes. For example, many intracellular proteins have enzymatic activity such as protein kinase activity, protein phosphatase activity, protease activity, nucleotide cyclase activity, polymerase activity and the like. Intracellular proteins also serve as docking proteins that are involved in organizing complexes of proteins, or targeting proteins to various subcellular localizations, and are involved in maintaining the structural integrity of organelles.

[0037] An increasingly appreciated concept in characterizing intracellular proteins is the presence in the proteins of one or more motifs for which defined functions have been attributed. In addition to the highly conserved sequences found in the enzymatic domain of proteins, highly conserved sequences have been identified in proteins that are involved in protein-protein interaction. For example, Src-homology-2 (SH2) domains bind tyrosine-phosphorylated targets in a sequence dependent manner. PTB domains, which are distinct from SH2 domains, also bind tyrosine phosphorylated targets. SH3 domains bind to proline-rich targets. In addition, PH domains, tetratricopeptide repeats and WD domains to name only a few, have been shown to mediate protein-protein interactions. Some of these may also be involved in binding to phospholipids or other second messengers. As will be appreciated by one of ordinary skill in the art, these motifs can be identified on the basis of primary sequence; thus, an analysis of the sequence of proteins may provide insight into both the enzymatic potential of the molecule and/or molecules with which the protein may associate.

[0038] In a preferred embodiment, the CA sequences are transmembrane proteins. Transmembrane proteins are molecules that span the phospholipid bilayer of a cell. They may have an intracellular domain, an extracellular domain, or both. The intracellular domains of such proteins may have a number of functions including those already described for intracellular proteins. For example, the intracellular domain may have enzymatic activity and/or may serve as a binding site for additional proteins. Frequently the intracellular domain of transmembrane proteins serves both roles. For example certain receptor tyrosine kinases have both protein kinase activity and SH2 domains. In addition, autophosphorylation of tyrosines on the receptor molecule itself, creates binding sites for additional SH2 domain containing proteins.

[0039] Transmembrane proteins may contain from one to many transmembrane domains. For example, receptor tyrosine kinases, certain cytokine receptors, receptor guanylyl cyclases and receptor serine/threonine protein kinases contain a single transmembrane domain. However, various other proteins including channels and adenylyl cyclases contain numerous transmembrane domains. Many important cell surface receptors are classified as “seven transmembrane domain” proteins, as they contain 7 membrane spanning regions. Important transmembrane protein receptors include, but are not limited to insulin receptor, insulin-like growth factor receptor, human growth hormone receptor, glucose transporters, transferrin receptor, epidermal growth factor receptor, low density lipoprotein receptor, epidermal growth factor receptor, leptin receptor, interleukin receptors, e.g. IL-1 receptor, IL-2 receptor, etc.

[0040] Characteristics of transmembrane domains include approximately 20 consecutive hydrophobic amino acids that may be followed by charged amino acids. Therefore, upon analysis of the amino acid sequence of a particular protein, the localization and number of transmembrane domains within the protein may be predicted.

[0041] The extracellular domains of transmembrane proteins are diverse; however, conserved motifs are found repeatedly among various extracellular domains. Conserved structure and/or functions have been ascribed to different extracellular motifs. For example, cytokine receptors are characterized by a cluster of cysteines and a WSXWS (W=tryptophan, S=serine, X=any amino acid) motif. Immunoglobulin-like domains are highly conserved. Mucin-like domains may be involved in cell adhesion and leucine-rich repeats participate in protein-protein interactions.

[0042] Many extracellular domains are involved in binding to other molecules. In one aspect, extracellular domains are receptors. Factors that bind the receptor domain include circulating ligands, which may be peptides, proteins, or small molecules such as adenosine and the like. For example, growth factors such as EGF, FGF and PDGF are circulating growth factors that bind to their cognate receptors to initiate a variety of cellular responses. Other factors include cytokines, mitogenic factors, neurotrophic factors and the like. Extracellular domains also bind to cell-associated molecules. In this respect, they mediate cell-cell interactions. Cell-associated ligands can be tethered to the cell for example via a glycosylphosphatidylinositol (GPI) anchor, or may themselves be transmembrane proteins. Extracellular domains also associate with the extracellular matrix and contribute to the maintenance of the cell structure.

[0043] CA proteins that are transmembrane are particularly preferred in the present invention as they are good targets for immunotherapeutics, as are described herein. In addition, as outlined below, transmembrane proteins can be also useful in imaging modalities.

[0044] It will also be appreciated by those in the art that a transmembrane protein can be made soluble by removing transmembrane sequences, for example through recombinant methods. Furthermore, transmembrane proteins that have been made soluble can be made to be secreted through recombinant means by adding an appropriate signal sequence.

[0045] In a preferred embodiment, the CA proteins are secreted proteins; the secretion of which can be either constitutive or regulated. These proteins have a signal peptide or signal sequence that targets the molecule to the secretory pathway. Secreted proteins are involved in numerous physiological events; by virtue of their circulating nature, they serve to transmit signals to various other cell types. The secreted protein may function in an autocrine manner (acting on the cell that secreted the factor), a paracrine manner (acting on cells in close proximity to the cell that secreted the factor) or an endocrine manner (acting on cells at a distance). Thus secreted molecules find use in modulating or altering numerous aspects of physiology. CA proteins that are secreted proteins are particularly preferred in the present invention as they serve as good targets for diagnostic markers, for example for blood tests.

[0046] An CA sequence is initially identified by substantial nucleic acid and/or amino acid sequence homology to the CA sequences outlined herein. Such homology can be based upon the overall nucleic acid or amino acid sequence, and is generally determined as outlined below, using either homology programs or hybridization conditions.

[0047] As used herein, a nucleic acid is a “CA nucleic acid” if the overall homology of the nucleic acid sequence to one of the nucleic acids of Tables 1-10 is preferably greater than about 75%, more preferably greater than about 80%, even more preferably greater than about 85% and most preferably greater than 90%. In some embodiments the homology will be as high as about 93 to 95 or 98%. In a preferred embodiment, the sequences which are used to determine sequence identity or similarity are selected from those of the nucleic acids of Tables 1-10. In another embodiment, the sequences are naturally occurring allelic variants of the sequences of the nucleic acids of Tables 1-10. In another embodiment, the sequences are sequence variants as further described herein.

[0048] Homology in this context means sequence similarity or identity, with identity being preferred. A preferred comparison for homology purposes is to compare the sequence containing sequencing errors to the correct sequence. This homology will be determined using standard techniques known in the art, including, but not limited to, the local homology algorithm of Smith & Waterman, Adv. Appl. Math. 2:482 (1981), by the homology alignment algorithm of Needleman & Wunsch, J. Mol. Biol. 48:443 (1970), by the search for similarity method of Pearson & Lipman, PNAS USA 85:2444 (1988), by computerized implementations of these algorithms (GAP, BESTFIT, FASTA, and TFASTA in the Wisconsin Genetics Software Package, Genetics Computer Group, 575 Science Drive, Madison, Wis.), the Best Fit sequence program described by Devereux et al., Nucl. Acid Res. 12:387-395 (1984), preferably using the default settings, or by inspection.

[0049] One example of a useful algorithm is PILEUP. PILEUP creates a multiple sequence alignment from a group of related sequences using progressive, pairwise alignments. It can also plot a tree showing the clustering relationships used to create the alignment. PILEUP uses a simplification of the progressive alignment method of Feng & Doolittle, J. Mol. Evol. 35:351-360 (1987); the method is similar to that described by Higgins & Sharp CABIOS 5:151-153 (1989). Useful PILEUP parameters including a default gap weight of 3.00, a default gap length weight of 0.10, and weighted end gaps.

[0050] Another example of a useful algorithm is the BLAST algorithm, described in Altschul et al., J. Mol. Biol. 215, 403-410, (1990) and Karlin et al., PNAS USA 90:5873-5787 (1993). A particularly useful BLAST program is the WU-BLAST-2 program which was obtained from Altschul et al., Methods in Enzymology, 266: 460-480 (1996); http://blast.wustl]. WU-BLAST-2 uses several search parameters, most of which are set to the default values. The adjustable parameters are set with the following values: overlap span=1, overlap fraction=0.125, word threshold (T)=11. The HSP S and HSP S2 parameters are dynamic values and are established by the program itself depending upon the composition of the particular sequence and composition of the particular database against which the sequence of interest is being searched; however, the values may be adjusted to increase sensitivity. A % amino acid sequence identity value is determined by the number of matching identical residues divided by the total number of residues of the “longer” sequence in the aligned region. The “longer” sequence is the one having the most actual residues in the aligned region (gaps introduced by WU-Blast-2 to maximize the alignment score are ignored).

[0051] Thus, “percent (%) nucleic acid sequence identity” is defined as the percentage of nucleotide residues in a candidate sequence that are identical with the nucleotide residues of the nucleic acids of Tables 1-10. A preferred method utilizes the BLASTN module of WU-BLAST-2 set to the default parameters, with overlap span and overlap fraction set to 1 and 0.125, respectively.

[0052] The alignment may include the introduction of gaps in the sequences to be aligned. In addition, for sequences which contain either more or fewer nucleotides than those of the nucleic acids of Tables 1-10, it is understood that the percentage of homology will be determined based on the number of homologous nucleosides in relation to the total number of nucleosides. Thus, for example, homology of sequences shorter than those of the sequences identified herein and as discussed below, will be determined using the number of nucleosides in the shorter sequence.

[0053] In one embodiment, the nucleic acid homology is determined through hybridization studies. Thus, for example, nucleic acids which hybridize under high stringency to the nucleic acids identified in the figures, or their complements, are considered CA sequences. High stringency conditions are known in the art; see for example Maniatis et al., Molecular Cloning: A Laboratory Manual, 2d Edition, 1989, and Short Protocols in Molecular Biology, ed. Ausubel, et al., both of which are hereby incorporated by reference. Stringent conditions are sequence-dependent and will be different in different circumstances. Longer sequences hybridize specifically at higher temperatures. An extensive guide to the hybridization of nucleic acids is found in Tijssen, Techniques in Biochemistry and Molecular Biology—Hybridization with Nucleic Acid Probes, “Overview of principles of hybridization and the strategy of nucleic acid assays” (1993). Generally, stringent conditions are selected to be about 5-10° C. lower than the thermal melting point (Tm) for the specific sequence at a defined ionic strength pH. The Tm is the temperature (under defined ionic strength, pH and nucleic acid concentration) at which 50% of the probes complementary to the target hybridize to the target sequence at equilibrium (as the target sequences are present in excess, at Tm, 50% of the probes are occupied at equilibrium). Stringent conditions will be those in which the salt concentration is less than about 1.0 M sodium ion, typically about 0.01 to 1.0 M sodium ion concentration (or other salts) at pH 7.0 to 8.3 and the temperature is at least about 30° C. for short probes (e.g. 10 to 50 nucleotides) and at least about 60° C. for long probes (e.g. greater than 50 nucleotides). Stringent conditions may also be achieved with the addition of destabilizing agents such as formamide.

[0054] In another embodiment, less stringent hybridization conditions are used; for example, moderate or low stringency conditions may be used, as are known in the art; see Maniatis and Ausubel, supra, and Tijssen, supra.

[0055] In addition, the CA nucleic acid sequences of the invention are fragments of larger genes, i.e. they are nucleic acid segments. Alternatively, the CA nucleic acid sequences can serve as indicators of oncogene position, for example, the CA sequence may be an enhancer that activates a protooncogene. “Genes” in this context includes coding regions, non-coding regions, and mixtures of coding and non-coding regions. Accordingly, as will be appreciated by those in the art, using the sequences provided herein, additional sequences of the CA genes can be obtained, using techniques well known in the art for cloning either longer sequences or the full length sequences; see Maniatis et al., and Ausubel, et al., supra, hereby expressly incorporated by reference. In general, this is done using PCR, for example, kinetic PCR.

[0056] Once the CA nucleic acid is identified, it can be cloned and, if necessary, its constituent parts recombined to form the entire CA nucleic acid. Once isolated from its natural source, e.g., contained within a plasmid or other vector or excised therefrom as a linear nucleic acid segment, the recombinant CA nucleic acid can be further used as a probe to identify and isolate other CA nucleic acids, for example additional coding regions. It can also be used as a “precursor” nucleic acid to make modified or variant CA nucleic acids and proteins.

[0057] The CA nucleic acids of the present invention are used in several ways. In a first embodiment, nucleic acid probes to the CA nucleic acids are made and attached to biochips to be used in screening and diagnostic methods, as outlined below, or for administration, for example for gene therapy and/or antisense applications. Alternatively, the CA nucleic acids that include coding regions of CA proteins can be put into expression vectors for the expression of CA proteins, again either for screening purposes or for administration to a patient.

[0058] In a preferred embodiment, nucleic acid probes to CA nucleic acids (both the nucleic acid sequences outlined in the figures and/or the complements thereof) are made. The nucleic acid probes attached to the biochip are designed to be substantially complementary to the CA nucleic acids, i.e. the target sequence (either the target sequence of the sample or to other probe sequences, for example in sandwich assays), such that hybridization of the target sequence and the probes of the present invention occurs. As outlined below, this complementarity need not be perfect; there may be any number of base pair mismatches which will interfere with hybridization between the target sequence and the single stranded nucleic acids of the present invention. However, if the number of mutations is so great that no hybridization can occur under even the least stringent of hybridization conditions, the sequence is not a complementary target sequence. Thus, by “substantially complementary” herein is meant that the probes are sufficiently complementary to the target sequences to hybridize under normal reaction conditions, particularly high stringency conditions, as outlined herein.

[0059] A nucleic acid probe is generally single stranded but can be partially single and partially double stranded. The strandedness of the probe is dictated by the structure, composition, and properties of the target sequence. In general, the nucleic acid probes range from about 8 to about 100 bases long, with from about 10 to about 80 bases being preferred, and from about 30 to about 50 bases being particularly preferred. That is, generally whole genes are not used. In some embodiments, much longer nucleic acids can be used, up to hundreds of bases.

[0060] In a preferred embodiment, more than one probe per sequence is used, with either overlapping probes or probes to different sections of the target being used. That is, two, three, four or more probes, with three being preferred, are used to build in a redundancy for a particular target. The probes can be overlapping (i.e. have some sequence in common), or separate.

[0061] As will be appreciated by those in the art, nucleic acids can be attached or immobilized to a solid support in a wide variety of ways. By “immobilized” and grammatical equivalents herein is meant the association or binding between the nucleic acid probe and the solid support is sufficient to be stable under the conditions of binding, washing, analysis, and removal as outlined below. The binding can be covalent or non-covalent. By “non-covalent binding” and grammatical equivalents herein is meant one or more of either electrostatic, hydrophilic, and hydrophobic interactions. Included in non-covalent binding is the covalent attachment of a molecule, such as, streptavidin to the support and the non-covalent binding of the biotinylated probe to the streptavidin. By “covalent binding” and grammatical equivalents herein is meant that the two moieties, the solid support and the probe, are attached by at least one bond, including sigma bonds, pi bonds and coordination bonds. Covalent bonds can be formed directly between the probe and the solid support or can be formed by a cross linker or by inclusion of a specific reactive group on either the solid support or the probe or both molecules. Immobilization may also involve a combination of covalent and non-covalent interactions.

[0062] In general, the probes are attached to the biochip in a wide variety of ways, as will be appreciated by those in the art. As described herein, the nucleic acids can either be synthesized first, with subsequent attachment to the biochip, or can be directly synthesized on the biochip.

[0063] The biochip comprises a suitable solid substrate. By “substrate” or “solid support” or other grammatical equivalents herein is meant any material that can be modified to contain discrete individual sites appropriate for the attachment or association of the nucleic acid probes and is amenable to at least one detection method. As will be appreciated by those in the art, the number of possible substrates are very large, and include, but are not limited to, glass and modified or functionalized glass, plastics (including acrylics, polystyrene and copolymers of styrene and other materials, polypropylene, polyethylene, polybutylene, polyurethanes, Teflon™, etc.), polysaccharides, nylon or nitrocellulose, resins, silica or silica-based materials including silicon and modified silicon, carbon, metals, inorganic glasses, etc. In general, the substrates allow optical detection and do not appreciably fluoresce.

[0064] In a preferred embodiment, the surface of the biochip and the probe may be derivatized with chemical functional groups for subsequent attachment of the two. Thus, for example, the biochip is derivatized with a chemical functional group including, but not limited to, amino groups, carboxy groups, oxo groups and thiol groups, with amino groups being particularly preferred. Using these functional groups, the probes can be attached using functional groups on the probes. For example, nucleic acids containing amino groups can be attached to surfaces comprising amino groups, for example using linkers as are known in the art; for example, homo-or hetero-bifunctional linkers as are well known (see 1994 Pierce Chemical Company catalog, technical section on cross-linkers, pages 155-200, incorporated herein by reference). In addition, in some cases, additional linkers, such as alkyl groups (including substituted and heteroalkyl groups) may be used.

[0065] In this embodiment, the oligonucleotides are synthesized as is known in the art, and then attached to the surface of the solid support. As will be appreciated by those skilled in the art, either the 5′ or 3′ terminus may be attached to the solid support, or attachment may be via an internal nucleoside.

[0066] In an additional embodiment, the immobilization to the solid support may be very strong, yet non-covalent. For example, biotinylated oligonucleotides can be made, which bind to surfaces covalently coated with streptavidin, resulting in attachment.

[0067] Alternatively, the oligonucleotides may be synthesized on the surface, as is known in the art. For example, photoactivation techniques utilizing photopolymerization compounds and techniques are used. In a preferred embodiment, the nucleic acids can be synthesized in situ, using well known photolithographic techniques, such as those described in WO 95/25116; WO 95/35505; U.S. Pat. Nos. 5,700,637 and 5,445,934; and references cited within, all of which are expressly incorporated by reference; these methods of attachment form the basis of the Affymetrix GeneChip technology.

[0068] In addition to the solid-phase technology represented by biochip arrays, gene expression can also be quantified using liquid-phase arrays. One such system is kinetic polymerase chain reaction (PCR). Kinetic PCR allows for the simultaneous amplification and quantification of specific nucleic acid sequences. The specificity is derived from synthetic oligonucleotide primers designed to preferentially adhere to single-stranded nucleic acid sequences bracketing the target site. This pair of oligonucleotide primers form specific, non-covalently bound complexes on each strand of the target sequence. These complexes facilitate in vitro transcription of double-stranded DNA in opposite orientations. Temperature cycling of the reaction mixture creates a continuous cycle of primer binding, transcription, and re-melting of the nucleic acid to individual strands. The result is an exponential increase of the target dsDNA product. This product can be quantified in real time either through the use of an intercalating dye or a sequence specific probe. SYBR® Greene I, is an example of an intercalating dye, that preferentially binds to dsDNA resulting in a concomitant increase in the fluorescent signal. Sequence specific probes, such as used with TaqMan® technology, consist of a fluorochrome and a quenching molecule covalently bound to opposite ends of an oligonucleotide. The probe is designed to selectively bind the target DNA sequence between the two primers. When the DNA strands are synthesized during the PCR reaction, the fluorochrome is cleaved from the probe by the exonuclease activity of the polymerase resulting in signal dequenching. The probe signaling method can be more specific than the intercalating dye method, but in each case, signal strength is proportional to the dsDNA product produced. Each type of quantification method can be used in multi-well liquid phase arrays with each well representing primers and/or probes specific to nucleic acid sequences of interest. When used with messenger RNA preparations of tissues or cell lines, and an array of probe/primer reactions can simultaneously quantify the expression of multiple gene products of interest. See Germer, S., et al., Genome Res. 10:258-266 (2000); Held, C. A., et al., Genome Res. 6, 986-994 (1996).

[0069] In a preferred embodiment, CA nucleic acids encoding CA proteins are used to make a variety of expression vectors to express CA proteins which can then be used in screening assays, as described below. The expression vectors may be either self-replicating extrachromosomal vectors or vectors which integrate into a host genome. Generally, these expression vectors include transcriptional and translational regulatory nucleic acid operably linked to the nucleic acid encoding the CA protein. The term “control sequences” refers to DNA sequences necessary for the expression of an operably linked coding sequence in a particular host organism. The control sequences that are suitable for prokaryotes, for example, include a promoter, optionally an operator sequence, and a ribosome binding site. Eukaryotic cells are known to utilize promoters, polyadenylation signals, and enhancers.

[0070] Nucleic acid is “operably linked” when it is placed into a functional relationship with another nucleic acid sequence. For example, DNA for a presequence or secretory leader is operably linked to DNA for a polypeptide if it is expressed as a preprotein that participates in the secretion of the polypeptide; a promoter or enhancer is operably linked to a coding sequence if it affects the transcription of the sequence; or a ribosome binding site is operably linked to a coding sequence if it is positioned so as to facilitate translation. Generally, “operably linked” means that the DNA sequences being linked are contiguous, and, in the case of a secretory leader, contiguous and in reading phase. However, enhancers do not have to be contiguous. Linking is accomplished by ligation at convenient restriction sites. If such sites do not exist, synthetic oligonucleotide adaptors or linkers are used in accordance with conventional practice. The transcriptional and translational regulatory nucleic acid will generally be appropriate to the host cell used to express the CA protein; for example, transcriptional and translational regulatory nucleic acid sequences from Bacillus are preferably used to express the CA protein in Bacillus. Numerous types of appropriate expression vectors, and suitable regulatory sequences are known in the art for a variety of host cells.

[0071] In general, the transcriptional and translational regulatory sequences may include, but are not limited to, promoter sequences, ribosomal binding sites, transcriptional start and stop sequences, translational start and stop sequences, and enhancer or activator sequences. In a preferred embodiment, the regulatory sequences include a promoter and transcriptional start and stop sequences.

[0072] Promoter sequences encode either constitutive or inducible promoters. The promoters may be either naturally occurring promoters or hybrid promoters. Hybrid promoters, which combine elements of more than one promoter, are also known in the art, and are useful in the present invention.

[0073] In addition, the expression vector may comprise additional elements. For example, the expression vector may have two replication systems, thus allowing it to be maintained in two organisms, for example in mammalian or insect cells for expression and in a procaryotic host for cloning and amplification. Furthermore, for integrating expression vectors, the expression vector contains at least one sequence homologous to the host cell genome, and preferably two homologous sequences which flank the expression construct. The integrating vector may be directed to a specific locus in the host cell by selecting the appropriate homologous sequence for inclusion in the vector. Constructs for integrating vectors are well known in the art.

[0074] In addition, in a preferred embodiment, the expression vector contains a selectable marker gene to allow the selection of transformed host cells. Selection genes are well known in the art and will vary with the host cell used.

[0075] The CA proteins of the present invention are produced by culturing a host cell transformed with an expression vector containing nucleic acid encoding an CA protein, under the appropriate conditions to induce or cause expression of the CA protein. The conditions appropriate for CA protein expression will vary with the choice of the expression vector and the host cell, and will be easily ascertained by one skilled in the art through routine experimentation. For example, the use of constitutive promoters in the expression vector will require optimizing the growth and proliferation of the host cell, while the use of an inducible promoter requires the appropriate growth conditions for induction. In addition, in some embodiments, the timing of the harvest is important. For example, the baculoviral systems used in insect cell expression are lytic viruses, and thus harvest time selection can be crucial for product yield.

[0076] Appropriate host cells include yeast, bacteria, archaebacteria, fungi, and insect, plant and animal cells, including mammalian cells. Of particular interest are Drosophila melanogaster cells, Saccharomyces cerevisiae and other yeasts, E coli, Bacillus subtilis, Sf9 cells, C129 cells, 293 cells, Neurospora, BHK, CHO, COS, HeLa cells, THP1 cell line (a macrophage cell line) and human cells and cell lines.

[0077] In a preferred embodiment, the CA proteins are expressed in mammalian cells. Mammalian expression systems are also known in the art, and include retroviral systems. A preferred expression vector system is a retroviral vector system such as is generally described in PCT/US97/01019 and PCT/US97101048, both of which are hereby expressly incorporated by reference. Of particular use as mammalian promoters are the promoters from mammalian viral genes, since the viral genes are often highly expressed and have a broad host range. Examples include the SV40 early promoter, mouse mammary tumor virus LTR promoter, adenovirus major late promoter, herpes simplex virus promoter, and the CMV promoter. Typically, transcription termination and polyadenylation sequences recognized by mammalian cells are regulatory regions located 3′ to the translation stop codon and thus, together with the promoter elements, flank the coding sequence. Examples of transcription terminator and polyadenlytion signals include those derived form SV40.

[0078] The methods of introducing exogenous nucleic acid into mammalian hosts, as well as other hosts, is well known in the art, and will vary with the host cell used. Techniques include dextran-mediated transfection, calcium phosphate precipitation, polybrene mediated transfection, protoplast fusion, electroporation, viral infection, encapsulation of the polynucleotide(s) in liposomes, and direct microinjection of the DNA into nuclei.

[0079] In a preferred embodiment, CA proteins are expressed in bacterial systems. Bacterial expression systems are well known in the art. Promoters from bacteriophage may also be used and are known in the art. In addition, synthetic promoters and hybrid promoters are also useful; for example, the tac promoter is a hybrid of the trp and lac promoter sequences. Furthermore, a bacterial promoter can include naturally occurring promoters of non-bacterial origin that have the ability to bind bacterial RNA polymerase and initiate transcription. In addition to a functioning promoter sequence, an efficient ribosome binding site is desirable. The expression vector may also include a signal peptide sequence that provides for secretion of the CA protein in bacteria. The protein is either secreted into the growth media (gram-positive bacteria) or into the periplasmic space, located between the inner and outer membrane of the cell (gram-negative bacteria). The bacterial expression vector may also include a selectable marker gene to allow for the selection of bacterial strains that have been transformed. Suitable selection genes include genes which render the bacteria resistant to drugs such as ampicillin, chloramphenicol, erythromycin, kanamycin, neomycin and tetracycline. Selectable markers also include biosynthetic genes, such as those in the histidine, tryptophan and leucine biosynthetic pathways. These components are assembled into expression vectors. Expression vectors for bacteria are well known in the art, and include vectors for Bacillus subtilis, E. coli, Streptococcus cremoris, and Streptococcus lividans, among others. The bacterial expression vectors are transformed into bacterial host cells using techniques well known in the art, such as calcium chloride treatment, electroporation, and others.

[0080] In one embodiment, CA proteins are produced in insect cells. Expression vectors for the transformation of insect cells, and in particular, baculovirus-based expression vectors, are well known in the art.

[0081] In a preferred embodiment, CA protein is produced in yeast cells. Yeast expression systems are well known in the art, and include expression vectors for Saccharomyces cerevisiae, Candida albicans and C. maltosa, Hansenula polymorpha, Kluyveromyces fragilis and K. lactis, Pichia guillerimondii and P. pastoris, Schizosaccharomyces pombe, and Yarrowia lipolytica.

[0082] The CA protein may also be made as a fusion protein, using techniques well known in the art. Thus, for example, for the creation of monoclonal antibodies. If the desired epitope is small, the CA protein may be fused to a carrier protein to form an immunogen. Alternatively, the CA protein may be made as a fusion protein to increase expression, or for other reasons. For example, when the CA protein is an CA peptide, the nucleic acid encoding the peptide may be linked to other nucleic acid for expression purposes.

[0083] In one embodiment, the CA nucleic acids, proteins and antibodies of the invention are labeled. By “labeled” herein is meant that a compound has at least one element, isotope or chemical compound attached to enable the detection of the compound. In general, labels fall into three classes: a) isotopic labels, which may be radioactive or heavy isotopes; b) immune labels, which may be antibodies or antigens; and c) colored or fluorescent dyes. The labels may be incorporated into the CA nucleic acids, proteins and antibodies at any position. For example, the label should be capable of producing, either directly or indirectly, a detectable signal. The detectable moiety may be a radioisotope, such as ³H, ¹⁴C, ³²P, ³⁵S, or ¹²⁵I a fluorescent or chemiluminescent compound, such as fluorescein isothiocyanate, rhodamine, or luciferin, or an enzyme, such as alkaline phosphatase, beta-galactosidase or horseradish peroxidase. Any method known in the art for conjugating the antibody to the label may be employed, including those methods described by Hunter et al., Nature, 144:945 9(1962); David et al., Biochemistry, 13:1014 (1974); Pain et al., J. Immunol. Meth., 40:219 (1981); and Nygren, J. Histochem. and Cytochem., 30:407 (1982).

[0084] Accordingly, the present invention also provides CA protein sequences. An CA protein of the present invention may be identified in several ways. “Protein” in this sense includes proteins, polypeptides, and peptides. As will be appreciated by those in the art, the nucleic acid sequences of the invention can be used to generate protein sequences. There are a variety of ways to do this, including cloning the entire gene and verifying its frame and amino acid sequence, or by comparing it to known sequences to search for homology to provide a frame, assuming the CA protein has homology to some protein in the database being used. Generally, the nucleic acid sequences are input into a program that will search all three frames for homology. This is done in a preferred embodiment using the following NCBI Advanced BLAST parameters. The program is blastx or blastn. The database is nr. The input data is as “Sequence in FASTA format”. The organism list is “none”. The “expect” is 10; the filter is default. The “descriptions” is 500, the “alignments” is 500, and the “alignment view” is pairwise. The “query Genetic Codes” is standard (1). The matrix is BLOSUM62; gap existence cost is 11, per residue gap cost is 1; and the lambda ratio is 0.85 default. This results in the generation of a putative protein sequence.

[0085] Also included within one embodiment of CA proteins are amino acid variants of the naturally occurring sequences, as determined herein. Preferably, the variants are preferably greater than about 75% homologous to the wild-type sequence, more preferably greater than about 80%, even more preferably greater than about 85% and most preferably greater than 90%. In some embodiments the homology will be as high as about 93 to 95 or 98%. As for nucleic acids, homology in this context means sequence similarity or identity, with identity being preferred. This homology will be determined using standard techniques known in the art as are outlined above for the nucleic acid homologies.

[0086] CA proteins of the present invention may be shorter or longer than the wild type amino acid sequences. Thus, in a preferred embodiment, included within the definition of CA proteins are portions or fragments of the wild type sequences herein. In addition, as outlined above, the CA nucleic acids of the invention may be used to obtain additional coding regions, and thus additional protein sequence, using techniques known in the art.

[0087] In a preferred embodiment, the CA proteins are derivative or variant CA proteins as compared to the wild-type sequence. That is, as outlined more fully below, the derivative CA peptide will contain at least one amino acid substitution, deletion or insertion, with amino acid substitutions being particularly preferred. The amino acid substitution, insertion or deletion may occur at any residue within the CA peptide.

[0088] Also included in an embodiment of CA proteins of the present invention are amino acid sequence variants. These variants fall into one or more of three classes: substitutional, insertional or deletional variants. These variants ordinarily are prepared by site specific mutagenesis of nucleotides in the DNA encoding the CA protein, using cassette or PCR mutagenesis or other techniques well known in the art, to produce DNA encoding the variant, and thereafter expressing the DNA in recombinant cell culture as outlined above. However, variant CA protein fragments having up to about 100-150 residues may be prepared by in vitro synthesis using established techniques. Amino acid sequence variants are characterized by the predetermined nature of the variation, a feature that sets them apart from naturally occurring allelic or interspecies variation of the CA protein amino acid sequence. The variants typically exhibit the same qualitative biological activity as the naturally occurring analogue, although variants can also be selected which have modified characteristics as will be more fully outlined below.

[0089] While the site or region for introducing an amino acid sequence variation is predetermined, the mutation per se need not be predetermined. For example, in order to optimize the performance of a mutation at a given site, random mutagenesis may be conducted at the target codon or region and the expressed CA variants screened for the optimal combination of desired activity. Techniques for making substitution mutations at predetermined sites in DNA having a known sequence are well known, for example, M13 primer mutagenesis and LAR mutagenesis. Screening of the mutants is done using assays of CA protein activities.

[0090] Amino acid substitutions are typically of single residues; insertions usually will be on the order of from about 1 to 20 amino acids, although considerably larger insertions may be tolerated. Deletions range from about 1 to about 20 residues, although in some cases deletions may be much larger.

[0091] Substitutions, deletions, insertions or any combination thereof may be used to arrive at a final derivative. Generally these changes are done on a few amino acids to minimize the alteration of the molecule. However, larger changes may be tolerated in certain circumstances. When small alterations in the characteristics of the CA protein are desired, substitutions are generally made in accordance with the following chart: CHART I Original Residue Exemplary Substitutions Ala Ser Arg Lys Asn Gln, His Asp Glu Cys Ser Gln Asn Glu Asp Gly Pro His Asn, Gln Ile Leu, Val Leu Ile, Val Lys Arg, Gln, Glu Met Leu, Ile Phe Met, Leu, Tyr Ser Thr Thr Ser Trp Tyr Tyr Trp, Phe Val Ile, Leu

[0092] Substantial changes in function or immunological identity are made by selecting substitutions that are less conservative than those shown in Chart I. For example, substitutions may be made which more significantly affect: the structure of the polypeptide backbone in the area of the alteration, for example the alpha-helical or beta-sheet structure; the charge or hydrophobicity of the molecule at the target site; or the bulk of the side chain. The substitutions which in general are expected to produce the greatest changes in the polypeptide's properties are those in which (a) a hydrophilic residue, e.g. seryl or threonyl is substituted for (or by) a hydrophobic residue, e.g. leucyl, isoleucyl, phenylalanyl, valyl or alanyl; (b) a cysteine or proline is substituted for (or by) any other residue; (c) a residue having an electropositive side chain, e.g. lysyl, arginyl, or histidyl, is substituted for (or by) an electronegative residue, e.g. glutamyl or aspartyl; or (d) a residue having a bulky side chain, e.g. phenylalanine, is substituted for (or by) one not having a side chain, e.g. glycine.

[0093] The variants typically exhibit the same qualitative biological activity and will elicit the same immune response as the naturally-occurring analogue, although variants also are selected to modify the characteristics of the CA proteins as needed. Alternatively, the variant may be designed such that the biological activity of the CA protein is altered. For example, glycosylation sites may be altered or removed, dominant negative mutations created, etc.

[0094] Covalent modifications of CA polypeptides are included within the scope of this invention, for example for use in screening. One type of covalent modification includes reacting targeted amino acid residues of an CA polypeptide with an organic derivatizing agent that is capable of reacting with selected side chains or the N-or C-terminal residues of an CA polypeptide. Derivatization with bifunctional agents is useful, for instance, for crosslinking CA polypeptides to a water-insoluble support matrix or surface for use in the method for purifying anti-CA antibodies or screening assays, as is more fully described below. Commonly used crosslinking agents include, e.g., 1,1-bis(diazoacetyl)-2-phenylethane, glutaraldehyde, N-hydroxysuccinimide esters, for example, esters with 4-azidosalicylic acid, homobifunctional imidoesters, including disuccinimidyl esters such as 3,3′-dithiobis(succinimidylpropionate), bifunctional maleimides such as bis-N-maleimido-1,8-octane and agents such as methyl-3-[(p-azidophenyl)dithio]propioimidate.

[0095] Other modifications include deamidation of glutaminyl and asparaginyl residues to the corresponding glutamyl and aspartyl residues, respectively, hydroxylation of proline and lysine, phosphorylation of hydroxyl groups of seryl, threonyl or tyrosyl residues, methylation of the a-amino groups of lysine, arginine, and histidine side chains [T. E. Creighton, Proteins: Structure and Molecular Properties, W. H. Freeman & Co., San Francisco, pp. 79-86 (1983)], acetylation of the N-terminal amine, and amidation of any C-terminal carboxyl group.

[0096] Another type of covalent modification of the CA polypeptide included within the scope of this invention comprises altering the native glycosylation pattern of the polypeptide. “Altering the native glycosylation pattern” is intended for purposes herein to mean deleting one or more carbohydrate moieties found in native sequence CA polypeptide, and/or adding one or more glycosylation sites that are not present in the native sequence CA polypeptide.

[0097] Addition of glycosylation sites to CA polypeptides may be accomplished by altering the amino acid sequence thereof. The alteration may be made, for example, by the addition of, or substitution by, one or more serine or threonine residues to the native sequence CA polypeptide (for O-linked glycosylation sites). The CA amino acid sequence may optionally be altered through changes at the DNA level, particularly by mutating the DNA encoding the CA polypeptide at preselected bases such that codons are generated that will translate into the desired amino acids.

[0098] Another means of increasing the number of carbohydrate moieties on the CA polypeptide is by chemical or enzymatic coupling of glycosides to the polypeptide. Such methods are described in the art, e.g., in WO 87/05330 published Sep. 11, 1987, and in Aplin and Wriston, LA Crit. Rev. Biochem., pp. 259-306 (1981).

[0099] Removal of carbohydrate moieties present on the CA polypeptide may be accomplished chemically or enzymatically or by mutational substitution of codons encoding for amino acid residues that serve as targets for glycosylation. Chemical deglycosylation techniques are known in the art and described, for instance, by Hakimuddin, et al., Arch. Biochem. Biophys., 259:52 (1987) and by Edge et al., Anal. Biochem., 118:131(1981). Enzymatic cleavage of carbohydrate moieties on polypeptides can be achieved by the use of a variety of endo-and exo-glycosidases as described by Thotakura et al., Meth. Enzymol., 138:350 (1987).

[0100] Another type of covalent modification of CA comprises linking the CA polypeptide to one of a variety of nonproteinaceous polymers, e.g., polyethylene glycol, polypropylene glycol, or polyoxyalkylenes, in the manner set forth in U.S. Pat. Nos. 4,640,835; 4,496,689; 4,301,144; 4,670,417; 4,791,192 or 4,179,337.

[0101] CA polypeptides of the present invention may also be modified in a way to form chimeric molecules comprising an CA polypeptide fused to another, heterologous polypeptide or amino acid sequence. In one embodiment, such a chimeric molecule comprises a fusion of an CA polypeptide with a tag polypeptide which provides an epitope to which an anti-tag antibody can selectively bind. The epitope tag is generally placed at the amino-or carboxyl-terminus of the CA polypeptide, although internal fusions may also be tolerated in some instances. The presence of such epitope-tagged forms of an CA polypeptide can be detected using an antibody against the tag polypeptide. Also, provision of the epitope tag enables the CA polypeptide to be readily purified by affinity purification using an anti-tag antibody or another type of affinity matrix that binds to the epitope tag. In an alternative embodiment, the chimeric molecule may comprise a fusion of an CA polypeptide with an immunoglobulin or a particular region of an immunoglobulin. For a bivalent form of the chimeric molecule, such a fusion could be to the Fc region of an IgG molecule.

[0102] Various tag polypeptides and their respective antibodies are well known in the art. Examples include poly-histidine (poly-his) or poly-histidine-glycine (poly-his-gly) tags; the flu HA tag polypeptide and its antibody 12CA5 [Field et al., Mol. Cell. Biol., 8:2159-2165 (1988)]; the c-myc tag and the 8F9, 3C7, 6E10, G4, B7 and 9E10 antibodies thereto [Evan et al., Molecular and Cellular Biology, 5:3610-3616 (1985)]; and the Herpes Simplex virus glycoprotein D (gD) tag and its antibody [Paborsky et al., Protein Engineering, 3(6):547-553 (1990)]. Other tag polypeptides include the Flag-peptide [Hopp et al., BioTechnology, 6:1204-1210 (1988)]; the KT3 epitope peptide [Martin et al., Science, 255:192-194 (1992)]; tubulin epitope peptide [Skinner et al., J. Biol. Chem., 266:15163-15166 (1991)]; and the T7 gene 10 protein peptide tag [Lutz-Freyermuth et al., Proc. Natl. Acad. Sci. USA, 87:6393-6397 (1990)].

[0103] Also included with the definition of CA protein in one embodiment are other CA proteins of the CA family, and CA proteins from other organisms, which are cloned and expressed as outlined below. Thus, probe or degenerate polymerase chain reaction (PCR) primer sequences may be used to find other related CA proteins from humans or other organisms. As will be appreciated by those in the art, particularly useful probe and/or PCR primer sequences include the unique areas of the CA nucleic acid sequence. As is generally known in the art, preferred PCR primers are from about 15 to about 35 nucleotides in length, with from about 20 to about 30 being preferred, and may contain inosine as needed. The conditions for the PCR reaction are well known in the art.

[0104] In addition, as is outlined herein, CA proteins can be made that are longer than those encoded by the nucleic acids of the figures, for example, by the elucidation of additional sequences, the addition of epitope or purification tags, the addition of other fusion sequences, etc.

[0105] CA proteins may also be identified as being encoded by CA nucleic acids. Thus, CA proteins are encoded by nucleic acids that will hybridize to the sequences of the sequence listings, or their complements, as outlined herein.

[0106] In a preferred embodiment, the invention provides CA antibodies. In a preferred embodiment, when the CA protein is to be used to generate antibodies, for example for immunotherapy, the CA protein should share at least one epitope or determinant with the full length protein. By “epitope” or “determinant” herein is meant a portion of a protein which will generate and/or bind an antibody or T-cell receptor in the context of MHC. Thus, in most instances, antibodies made to a smaller CA protein will be able to bind to the full length protein. In a preferred embodiment, the epitope is unique; that is, antibodies generated to a unique epitope show little or no cross-reactivity.

[0107] In one embodiment, the term “antibody” includes antibody fragments, as are known in the art, including Fab, Fab₂, single chain antibodies (Fv for example), chimeric antibodies, etc., either produced by the modification of whole antibodies or those synthesized de novo using recombinant DNA technologies.

[0108] Methods of preparing polyclonal antibodies are known to the skilled artisan. Polyclonal antibodies can be raised in a mammal, for example, by one or more injections of an immunizing agent and, if desired, an adjuvant. Typically, the immunizing agent and/or adjuvant will be injected in the mammal by multiple subcutaneous or intraperitoneal injections. The immunizing agent may include a protein encoded by a nucleic acid of the figures or fragment thereof or a fusion protein thereof. It may be useful to conjugate the immunizing agent to a protein known to be immunogenic in the mammal being immunized. Examples of such immunogenic proteins include but are not limited to keyhole limpet hemocyanin, serum albumin, bovine thyroglobulin, and soybean trypsin inhibitor. Examples of adjuvants which may be employed include Freund's complete adjuvant and MPL-TDM adjuvant (monophosphoryl Lipid A, synthetic trehalose dicorynomycolate). The immunization protocol may be selected by one skilled in the art without undue experimentation.

[0109] The antibodies may, alternatively, be monoclonal antibodies. Monoclonal antibodies may be prepared using hybridoma methods, such as those described by Kohler and Milstein, Nature, 256:495 (1975).

[0110] In a hybridoma method, a mouse, hamster, or other appropriate host animal, is typically immunized with an immunizing agent to elicit lymphocytes that produce or are capable of producing antibodies that will specifically bind to the immunizing agent. Alternatively, the lymphocytes may be immunized in vitro. The immunizing agent will typically include a polypeptide encoded by a nucleic acid of Tables 1-10, or fragment thereof or a fusion protein thereof. Generally, either peripheral blood lymphocytes (“PBLs”) are used if cells of human origin are desired, or spleen cells or lymph node cells are used if non-human mammalian sources are desired. The lymphocytes are then fused with an immortalized cell line using a suitable fusing agent, such as polyethylene glycol, to form a hybridoma cell [Goding, Monoclonal Antibodies: Principles and Practice, Academic Press, (1986) pp. 59-103]. Immortalized cell lines are usually transformed mammalian cells, particularly myeloma cells of rodent, bovine and human origin. Usually, rat or mouse myeloma cell lines are employed. The hybridoma cells may be cultured in a suitable culture medium that preferably contains one or more substances that inhibit the growth or survival of the unfused, immortalized cells. For example, if the parental cells lack the enzyme hypoxanthine guanine phosphoribosyl transferase (HGPRT or HPRT), the culture medium for the hybridomas typically will include hypoxanthine, aminopterin, and thymidine (“HAT medium”), which substances prevent the growth of HGPRT-deficient cells.

[0111] In one embodiment, the antibodies are bispecific antibodies. Bispecific antibodies are monoclonal, preferably human or humanized, antibodies that have binding specificities for at least two different antigens. In the present case, one of the binding specificities is for a protein encoded by a nucleic acid of Tables 1, or a fragment thereof, the other one is for any other antigen, and preferably for a cell-surface protein or receptor or receptor subunit, preferably one that is tumor specific.

[0112] In a preferred embodiment, the antibodies to CA are capable of reducing or eliminating the biological function of CA, as is described below. That is, the addition of anti-CA antibodies (either polyclonal or preferably monoclonal) to CA (or cells containing CA) may reduce or eliminate the CA activity. Generally, at least a 25% decrease in activity is preferred, with at least about 50% being particularly preferred and about a 95-100% decrease being especially preferred.

[0113] In a preferred embodiment the antibodies to the CA proteins are humanized antibodies. Humanized forms of non-human (e.g., murine) antibodies are chimeric molecules of immunoglobulins, immunoglobulin chains or fragments thereof (such as Fv, Fab, Fab′, F(ab′)₂ or other antigen binding subsequences of antibodies) which contain minimal sequence derived from non-human immunoglobulin. Humanized antibodies include human immunoglobulins (recipient antibody) in which residues form a complementary determining region (CDR) of the recipient are replaced by residues from a CDR of a non-human species (donor antibody) such as mouse, rat or rabbit having the desired specificity, affinity and capacity. In some instances, Fv framework residues of the human immunoglobulin are replaced by corresponding non-human residues. Humanized antibodies may also comprise residues which are found neither in the recipient antibody nor in the imported CDR or framework sequences. In general, the humanized antibody will comprise substantially all of at least one, and typically two, variable domains, in which all or substantially all of the CDR regions correspond to those of a non-human immunoglobulin and all or substantially all of the framework residues (FR) regions are those of a human immunoglobulin consensus sequence. The humanized antibody optimally also will comprise at least a portion of an immunoglobulin constant region (Fc), typically that of a human immunoglobulin [Jones et al., Nature, 321:522-525 (1986); Riechmann et al., Nature, 332:323-329 (1988); and Presta, Curr. Op. Struct. Biol., 2:593-596 (1992)].

[0114] Methods for humanizing non-human antibodies are well known in the art. Generally, a humanized antibody has one or more amino acid residues introduced into it from a source which is non-human. These non-human amino acid residues are often referred to as import residues, which are typically taken from an import variable domain. Humanization can be essentially performed following the method of Winter and co-workers [Jones et al., Nature, 321:522-525 (1986); Riechmann et al., Nature, 332:323-327 (1988); Verhoeyen et al., Science, 239:1534-1536 (1988)], by substituting rodent CDRs or CDR sequences for the corresponding sequences of a human antibody. Accordingly, such humanized antibodies are chimeric antibodies (U.S. Pat. No. 4,816,567), wherein substantially less than an intact human variable domain has been substituted by the corresponding sequence from a non-human species. In practice, humanized antibodies are typically human antibodies in which some CDR residues and possibly some FR residues are substituted by residues from analogous sites in rodent antibodies.

[0115] Human antibodies can also be produced using various techniques known in the art, including phage display libraries [Hoogenboom and Winter, J. Mol. Biol., 227:381 (1991); Marks et al., J. Mol. Biol., 222:581 (1991)]. The techniques of Cole et al. and Boerner et al. are also available for the preparation of human monoclonal antibodies [Cole et al., Monoclonal Antibodies and Cancer Therapy, Alan R. Liss, p. 77 (1985) and Boerner et al., J. Immunol., 147(1):86-95 (1991)]. Similarly, human antibodies can be made by introducing human immunoglobulin loci into transgenic animals, e.g., mice in which the endogenous immunoglobulin genes have been partially or completely inactivated. Upon challenge, human antibody production is observed, which closely resembles that seen in humans in all respects, including gene rearrangement, assembly, and antibody repertoire. This approach is described, for example, in U.S. Pat. Nos. 5,545,807; 5,545,806; 5,569,825; 5,625,126; 5,633,425; 5,661,016, and in the following scientific publications: Marks et al., Bio/Technology 10, 779-783 (1992); Lonberg et al., Nature 368 856-859 (1994); Morrison, Nature 368, 812-13 (1994); Fishwild et al., Nature Biotechnology 14, 845-51 (1996); Neuberger, Nature Biotechnology 14, 826 (1996); Lonberg and Huszar, Intern. Rev. Immunol. 13 65-93 (1995).

[0116] By immunotherapy is meant treatment of a carcinoma with an antibody raised against an CA protein. As used herein, immunotherapy can be passive or active. Passive immunotherapy as defined herein is the passive transfer of antibody to a recipient (patient). Active immunization is the induction of antibody and/or T-cell responses in a recipient (patient). Induction of an immune response is the result of providing the recipient with an antigen to which antibodies are raised. As appreciated by one of ordinary skill in the art, the antigen may be provided by injecting a polypeptide against which antibodies are desired to be raised into a recipient, or contacting the recipient with a nucleic acid capable of expressing the antigen and under conditions for expression of the antigen.

[0117] In a preferred embodiment, oncogenes which encode secreted growth factors may be inhibited by raising antibodies against CA proteins that are secreted proteins as described above. Without being bound by theory, antibodies used for treatment, bind and prevent the secreted protein from binding to its receptor, thereby inactivating the secreted CA protein.

[0118] In another preferred embodiment, the CA protein to which antibodies are raised is a transmembrane protein. Without being bound by theory, antibodies used for treatment, bind the extracellular domain of the CA protein and prevent it from binding to other proteins, such as circulating ligands or cell-associated molecules. The antibody may cause down-regulation of the transmembrane CA protein.

[0119] As will be appreciated by one of ordinary skill in the art, the antibody may be a competitive, non-competitive or uncompetitive inhibitor of protein binding to the extracellular domain of the CA protein. The antibody is also an antagonist of the CA protein. Further, the antibody prevents activation of the transmembrane CA protein. In one aspect, when the antibody prevents the binding of other molecules to the CA protein, the antibody prevents growth of the cell. The antibody may also sensitize the cell to cytotoxic agents, including, but not limited to TNF-α, TNF-β, IL-1, INF-γ and IL-2, or chemotherapeutic agents including 5FU, vinblastine, actinomycin D, cisplatin, methotrexate, and the like. In some instances the antibody belongs to a sub-type that activates serum complement when complexed with the transmembrane protein thereby mediating cytotoxicity. Thus, carcinomas may be treated by administering to a patient antibodies directed against the transmembrane CA protein.

[0120] In another preferred embodiment, the antibody is conjugated to a therapeutic moiety. In one aspect the therapeutic moiety is a small molecule that modulates the activity of the CA protein. In another aspect the therapeutic moiety modulates the activity of molecules associated with or in close proximity to the CA protein. The therapeutic moiety may inhibit enzymatic activity such as protease or protein kinase activity associated with carcinoma.

[0121] In a preferred embodiment, the therapeutic moiety may also be a cytotoxic agent. In this method, targeting the cytotoxic agent to tumor tissue or cells, results in a reduction in the number of afflicted cells, thereby reducing symptoms associated with carcinomas, including lymphoma. Cytotoxic agents are numerous and varied and include, but are not limited to, cytotoxic drugs or toxins or active fragments of such toxins. Suitable toxins and their corresponding fragments include diphtheria A chain, exotoxin A chain, ricin A chain, abrin A chain, curcin, crotin, phenomycin, enomycin and the like. Cytotoxic agents also include radiochemicals made by conjugating radioisotopes to antibodies raised against CA proteins, or binding of a radionuclide to a chelating agent that has been covalently attached to the antibody. Targeting the therapeutic moiety to transmembrane CA proteins not only serves to increase the local concentration of therapeutic moiety in the carcinoma of interest, i.e., lymphoma, but also serves to reduce deleterious side effects that may be associated with the therapeutic moiety.

[0122] In another preferred embodiment, the CA protein against which the antibodies are raised is an intracellular protein. In this case, the antibody may be conjugated to a protein which facilitates entry into the cell. In one case, the antibody enters the cell by endocytosis. In another embodiment, a nucleic acid encoding the antibody is administered to the individual or cell. Moreover, wherein the CA protein can be targeted within a cell, i.e., the nucleus, an antibody thereto contains a signal for that target localization, i.e., a nuclear localization signal.

[0123] The CA antibodies of the invention specifically bind to CA proteins. By “specifically bind” herein is meant that the antibodies bind to the protein with a binding constant in the range of at least 10⁻⁴-10⁻⁶ M⁻¹, with a preferred range being 10⁻⁷-10⁻⁹ M⁻¹.

[0124] In a preferred embodiment, the CA protein is purified or isolated after expression. CA proteins may be isolated or purified in a variety of ways known to those skilled in the art depending on what other components are present in the sample. Standard purification methods include electrophoretic, molecular, immunological and chromatographic techniques, including ion exchange, hydrophobic, affinity, and reverse-phase HPLC chromatography, and chromatofocusing. For example, the CA protein may be purified using a standard anti-CA antibody column. Ultrafiltration and diafiltration techniques, in conjunction with protein concentration, are also useful. For general guidance in suitable purification techniques, see Scopes, R., Protein Purification, Springer-Verlag, NY (1982). The degree of purification necessary will vary depending on the use of the CA protein. In some instances no purification will be necessary.

[0125] Once expressed and purified if necessary, the CA proteins and nucleic acids are useful in a number of applications.

[0126] In one aspect, the expression levels of genes are determined for different cellular states in the carcinoma phenotype; that is, the expression levels of genes in normal tissue and in carcinoma tissue (and in some cases, for varying severities of lymphoma that relate to prognosis, as outlined below) are evaluated to provide expression profiles. An expression profile of a particular cell state or point of development is essentially a “fingerprint” of the state; while two states may have any particular gene similarly expressed, the evaluation of a number of genes simultaneously allows the generation of a gene expression profile that is unique to the state of the cell. By comparing expression profiles of cells in different states, information regarding which genes are important (including both up- and down-regulation of genes) in each of these states is obtained. Then, diagnosis may be done or confirmed: does tissue from a particular patient have the gene expression profile of normal or carcinoma tissue.

[0127] “Differential expression,” or grammatical equivalents as used herein, refers to both qualitative as well as quantitative differences in the genes temporal and/or cellular expression patterns within and among the cells. Thus, a differentially expressed gene can qualitatively have its expression altered, including an activation or inactivation, in, for example, normal versus carcinoma tissue. That is, genes may be turned on or turned off in a particular state, relative to another state. As is apparent to the skilled artisan, any comparison of two or more states can be made. Such a qualitatively regulated gene will exhibit an expression pattern within a state or cell type which is detectable by standard techniques in one such state or cell type, but is not detectable in both. Alternatively, the determination is quantitative in that expression is increased or decreased; that is, the expression of the gene is either upregulated, resulting in an increased amount of transcript, or downregulated, resulting in a decreased amount of transcript. The degree to which expression differs need only be large enough to quantify via standard characterization techniques as outlined below, such as by use of Affymetrix GeneChip® expression arrays, Lockhart, Nature Biotechnology, 14:1675-1680 (1996), hereby expressly incorporated by reference. Other techniques include, but are not limited to, quantitative reverse transcriptase PCR, Northern analysis and RNase protection. As outlined above, preferably the change in expression (i.e. upregulation or downregulation) is at least about 50%, more preferably at least about 100%, more preferably at least about 150%, more preferably, at least about 200%, with from 300 to at least 1000% being especially preferred.

[0128] As will be appreciated by those in the art, this may be done by evaluation at either the gene transcript, or the protein level; that is, the amount of gene expression may be monitored using nucleic acid probes to the DNA or RNA equivalent of the gene transcript, and the quantification of gene expression levels, or, alternatively, the final gene product itself (protein) can be monitored, for example through the use of antibodies to the CA protein and standard immunoassays (ELISAs, etc.) or other techniques, including mass spectroscopy assays, 2D gel electrophoresis assays, etc. Thus, the proteins corresponding to CA genes, i.e. those identified as being important in a particular carcinoma phenotype, i.e., lymphoma, can be evaluated in a diagnostic test specific for that carcinoma.

[0129] In a preferred embodiment, gene expression monitoring is done and a number of genes, i.e. an expression profile, is monitored simultaneously, although multiple protein expression monitoring can be done as well. Similarly, these assays may be done on an individual basis as well.

[0130] In this embodiment, the CA nucleic acid probes may be attached to biochips as outlined herein for the detection and quantification of CA sequences in a particular cell. The assays are done as is known in the art. As will be appreciated by those in the art, any number of different CA sequences may be used as probes, with single sequence assays being used in some cases, and a plurality of the sequences described herein being used in other embodiments. In addition, while solid-phase assays are described, any number of solution based assays may be done as well.

[0131] In a preferred embodiment, both solid and solution based assays may be used to detect CA sequences that are up-regulated or down-regulated in carcinomas as compared to normal tissue. In instances where the CA sequence has been altered but shows the same expression profile or an altered expression profile, the protein will be detected as outlined herein.

[0132] In a preferred embodiment nucleic acids encoding the CA protein are detected. Although DNA or RNA encoding the CA protein may be detected, of particular interest are methods wherein the mRNA encoding a CA protein is detected. The presence of mRNA in a sample is an indication that the CA gene has been transcribed to form the mRNA, and suggests that the protein is expressed. Probes to detect the mRNA can be any nucleotide/deoxynucleotide probe that is complementary to and base pairs with the mRNA and includes but is not limited to oligonucleotides, cDNA or RNA. Probes also should contain a detectable label, as defined herein. In one method the mRNA is detected after immobilizing the nucleic acid to be examined on a solid support such as nylon membranes and hybridizing the probe with the sample. Following washing to remove the non-specifically bound probe, the label is detected. In another method detection of the mRNA is performed in situ. In this method permeabilized cells or tissue samples are contacted with a detectably labeled nucleic acid probe for sufficient time to allow the probe to hybridize with the target mRNA. Following washing to remove the non-specifically bound probe, the label is detected. For example a digoxygenin labeled riboprobe (RNA probe) that is complementary to the mRNA encoding a CA protein is detected by binding the digoxygenin with an anti-digoxygenin secondary antibody and developed with nitro blue tetrazolium and 5-bromo-4-chloro-3-indoyl phosphate.

[0133] In a preferred embodiment, any of the three classes of proteins as described herein (secreted, transmembrane or intracellular proteins) are used in diagnostic assays. The CA proteins, antibodies, nucleic acids, modified proteins and cells containing CA sequences are used in diagnostic assays. This can be done on an individual gene or corresponding polypeptide level, or as sets of assays.

[0134] As described and defined herein, CA proteins find use as markers of carcinomas, including lymphomas such as, but not limited to, Hodgkin's and non-Hodgkin lymphoma. Detection of these proteins in putative carcinoma tissue or patients allows for a determination or diagnosis of the type of carcinoma. Numerous methods known to those of ordinary skill in the art find use in detecting carcinomas. In one embodiment, antibodies are used to detect CA proteins. A preferred method separates proteins from a sample or patient by electrophoresis on a gel (typically a denaturing and reducing protein gel, but may be any other type of gel including isoelectric focusing gels and the like). Following separation of proteins, the CA protein is detected by immunoblotting with antibodies raised against the CA protein. Methods of immunoblotting are well known to those of ordinary skill in the art.

[0135] In another preferred method, antibodies to the CA protein find use in in situ imaging techniques. In this method cells are contacted with from one to many antibodies to the CA protein(s). Following washing to remove non-specific antibody binding, the presence of the antibody or antibodies is detected. In one embodiment the antibody is detected by incubating with a secondary antibody that contains a detectable label. In another method the primary antibody to the CA protein(s) contains a detectable label. In another preferred embodiment each one of multiple primary antibodies contains a distinct and detectable label. This method finds particular use in simultaneous screening for a plurality of CA proteins. As will be appreciated by one of ordinary skill in the art, numerous other histological imaging techniques are useful in the invention.

[0136] In a preferred embodiment the label is detected in a fluorometer which has the ability to detect and distinguish emissions of different wavelengths. In addition, a fluorescence activated cell sorter (FACS) can be used in the method.

[0137] In another preferred embodiment, antibodies find use in diagnosing carcinomas from blood samples. As previously described, certain CA proteins are secreted/circulating molecules. Blood samples, therefore, are useful as samples to be probed or tested for the presence of secreted CA proteins. Antibodies can be used to detect the CA proteins by any of the previously described immunoassay techniques including ELISA, immunoblotting (Western blotting), immunoprecipitation, BIACORE technology and the like, as will be appreciated by one of ordinary skill in the art.

[0138] In a preferred embodiment, in situ hybridization of labeled CA nucleic acid probes to tissue arrays is done. For example, arrays of tissue samples, including CA tissue and/or normal tissue, are made. In situ hybridization as is known in the art can then be done.

[0139] It is understood that when comparing the expression fingerprints between an individual and a standard, the skilled artisan can make a diagnosis as well as a prognosis. It is further understood that the genes which indicate the diagnosis may differ from those which indicate the prognosis.

[0140] In a preferred embodiment, the CA proteins, antibodies, nucleic acids, modified proteins and cells containing CA sequences are used in prognosis assays. As above, gene expression profiles can be generated that correlate to carcinoma, especially lymphoma, severity, in terms of long term prognosis. Again, this may be done on either a protein or gene level, with the use of genes being preferred. As above, the CA probes are attached to biochips for the detection and quantification of CA sequences in a tissue or patient. The assays proceed as outlined for diagnosis.

[0141] In a preferred embodiment, any of the CA sequences as described herein are used in drug screening assays. The CA proteins, antibodies, nucleic acids, modified proteins and cells containing CA sequences are used in drug screening assays or by evaluating the effect of drug candidates on a “gene expression profile” or expression profile of polypeptides. In one embodiment, the expression profiles are used, preferably in conjunction with high throughput screening techniques to allow monitoring for expression profile genes after treatment with a candidate agent, Zlokarnik, et al., Science 279, 84-8 (1998), Heid, et al., Genome Res., 6:986-994 (1996).

[0142] In a preferred embodiment, the CA proteins, antibodies, nucleic acids, modified proteins and cells containing the native or modified CA proteins are used in screening assays. That is, the present invention provides novel methods for screening for compositions which modulate the carcinoma phenotype. As above, this can be done by screening for modulators of gene expression or for modulators of protein activity. Similarly, this may be done on an individual gene or protein level or by evaluating the effect of drug candidates on a “gene expression profile”. In a preferred embodiment, the expression profiles are used, preferably in conjunction with high throughput screening techniques to allow monitoring for expression profile genes after treatment with a candidate agent, see Zlokarnik, supra.

[0143] Having identified the CA genes herein, a variety of assays to evaluate the effects of agents on gene expression may be executed. In a preferred embodiment, assays may be run on an individual gene or protein level. That is, having identified a particular gene as aberrantly regulated in carcinoma, candidate bioactive agents may be screened to modulate the genes response. “Modulation” thus includes both an increase and a decrease in gene expression or activity. The preferred amount of modulation will depend on the original change of the gene expression in normal versus tumor tissue, with changes of at least 10%, preferably 50%, more preferably 100-300%, and in some embodiments 300-1000% or greater. Thus, if a gene exhibits a 4 fold increase in tumor compared to normal tissue, a decrease of about four fold is desired; a 10 fold decrease in tumor compared to normal tissue gives a 10 fold increase in expression for a candidate agent is desired, etc. Alternatively, where the CA sequence has been altered but shows the same expression profile or an altered expression profile, the protein will be detected as outlined herein.

[0144] As will be appreciated by those in the art, this may be done by evaluation at either the gene or the protein level; that is, the amount of gene expression may be monitored using nucleic acid probes and the quantification of gene expression levels, or, alternatively, the level of the gene product itself can be monitored, for example through the use of antibodies to the CA protein and standard immunoassays. Alternatively, binding and bioactivity assays with the protein may be done as outlined below.

[0145] In a preferred embodiment, gene expression monitoring is done and a number of genes, i.e. an expression profile, is monitored simultaneously, although multiple protein expression monitoring can be done as well.

[0146] In this embodiment, the CA nucleic acid probes are attached to biochips as outlined herein for the detection and quantification of CA sequences in a particular cell. The assays are further described below.

[0147] Generally, in a preferred embodiment, a candidate bioactive agent is added to the cells prior to analysis. Moreover, screens are provided to identify a candidate bioactive agent which modulates a particular type of carcinoma, modulates CA proteins, binds to a CA protein, or interferes between the binding of a CA protein and an antibody.

[0148] The term “candidate bioactive agent” or “drug candidate” or grammatical equivalents as used herein describes any molecule, e.g., protein, oligopeptide, small organic or inorganic molecule, polysaccharide, polynucleotide, etc., to be tested for bioactive agents that are capable of directly or indirectly altering either the carcinoma phenotype, binding to and/or modulating the bioactivity of an CA protein, or the expression of a CA sequence, including both nucleic acid sequences and protein sequences. In a particularly preferred embodiment, the candidate agent suppresses a CA phenotype, for example to a normal tissue fingerprint. Similarly, the candidate agent preferably suppresses a severe CA phenotype. Generally a plurality of assay mixtures are run in parallel with different agent concentrations to obtain a differential response to the various concentrations. Typically, one of these concentrations serves as a negative control, i.e., at zero concentration or below the level of detection.

[0149] In one aspect, a candidate agent will neutralize the effect of an CA protein. By “neutralize” is meant that activity of a protein is either inhibited or counter acted against so as to have substantially no effect on a cell.

[0150] Candidate agents encompass numerous chemical classes, though typically they are organic or inorganic molecules, preferably small organic compounds having a molecular weight of more than 100 and less than about 2,500 daltons. Preferred small molecules are less than 2000, or less than 1500 or less than 1000 or less than 500 D. Candidate agents comprise functional groups necessary for structural interaction with proteins, particularly hydrogen bonding, and typically include at least an amine, carbonyl, hydroxyl or carboxyl group, preferably at least two of the functional chemical groups. The candidate agents often comprise cyclical carbon or heterocyclic structures and/or aromatic or polyaromatic structures substituted with one or more of the above functional groups. Candidate agents are also found among biomolecules including peptides, saccharides, fatty acids, steroids, purines, pyrimidines, derivatives, structural analogs or combinations thereof. Particularly preferred are peptides.

[0151] Candidate agents are obtained from a wide variety of sources including libraries of synthetic or natural compounds. For example, numerous means are available for random and directed synthesis of a wide variety of organic compounds and biomolecules, including expression of randomized oligonucleotides. Alternatively, libraries of natural compounds in the form of bacterial, fungal, plant and animal extracts are available or readily produced. Additionally, natural or synthetically produced libraries and compounds are readily modified through conventional chemical, physical and biochemical means. Known pharmacological agents may be subjected to directed or random chemical modifications, such as acylation, alkylation, esterification, amidification to produce structural analogs.

[0152] In a preferred embodiment, the candidate bioactive agents are proteins. By “protein” herein is meant at least two covalently attached amino acids, which includes proteins, polypeptides, oligopeptides and peptides. The protein may be made up of naturally occurring amino acids and peptide bonds, or synthetic peptidomimetic structures. Thus “amino acid”, or “peptide residue”, as used herein means both naturally occurring and synthetic amino acids. For example, homo-phenylalanine, citrulline and noreleucine are considered amino acids for the purposes of the invention. “Amino acid” also includes imino acid residues such as proline and hydroxyproline. The side chains may be in either the (R) or the (S) configuration. In the preferred embodiment, the amino acids are in the (S) or L-configuration. If non-naturally occurring side chains are used, non-amino acid substituents may be used, for example to prevent or retard in vivo degradations.

[0153] In a preferred embodiment, the candidate bioactive agents are naturally occurring proteins or fragments of naturally occurring proteins. Thus, for example, cellular extracts containing proteins, or random or directed digests of proteinaceous cellular extracts, may be used. In this way libraries of procaryotic and eucaryotic proteins may be made for screening in the methods of the invention. Particularly preferred in this embodiment are libraries of bacterial, fungal, viral, and mammalian proteins, with the latter being preferred, and human proteins being especially preferred.

[0154] In a preferred embodiment, the candidate bioactive agents are peptides of from about 5 to about 30 amino acids, with from about 5 to about 20 amino acids being preferred, and from about 7 to about 15 being particularly preferred. The peptides may be digests of naturally occurring proteins as is outlined above, random peptides, or “biased” random peptides. By “randomized” or grammatical equivalents herein is meant that each nucleic acid and peptide consists of essentially random nucleotides and amino acids, respectively. Since generally these random peptides (or nucleic acids, discussed below) are chemically synthesized, they may incorporate any nucleotide or amino acid at any position. The synthetic process can be designed to generate randomized proteins or nucleic acids, to allow the formation of all or most of the possible combinations over the length of the sequence, thus forming a library of randomized candidate bioactive proteinaceous agents.

[0155] In one embodiment, the library is fully randomized, with no sequence preferences or constants at any position. In a preferred embodiment, the library is biased. That is, some positions within the sequence are either held constant, or are selected from a limited number of possibilities. For example, in a preferred embodiment, the nucleotides or amino acid residues are randomized within a defined class, for example, of hydrophobic amino acids, hydrophilic residues, sterically biased (either small or large) residues, towards the creation of nucleic acid binding domains, the creation of cysteines, for cross-linking, prolines for SH-3 domains, serines, threonines, tyrosines or histidines for phosphorylation sites, etc., or to purines, etc.

[0156] In a preferred embodiment, the candidate bioactive agents are nucleic acids, as defined above.

[0157] As described above generally for proteins, nucleic acid candidate bioactive agents may be naturally occurring nucleic acids, random nucleic acids, or “biased” random nucleic acids. For example, digests of procaryotic or eucaryotic genomes may be used as is outlined above for proteins.

[0158] In a preferred embodiment, the candidate bioactive agents are organic chemical moieties, a wide variety of which are available in the literature.

[0159] In assays for altering the expression profile of one or more CA genes, after the candidate agent has been added and the cells allowed to incubate for some period of time, the sample containing the target sequences to be analyzed is added to the biochip. If required, the target sequence is prepared using known techniques. For example, the sample may be treated to lyse the cells, using known lysis buffers, electroporation, etc., with purification and/or amplification such as PCR occurring as needed, as will be appreciated by those in the art. For example, an in vitro transcription with labels covalently attached to the nucleosides is done. Generally, the nucleic acids are labeled with a label as defined herein, with biotin-FITC or PE, cy3 and cy5 being particularly preferred.

[0160] In a preferred embodiment, the target sequence is labeled with, for example, a fluorescent, chemiluminescent, chemical, or radioactive signal, to provide a means of detecting the target sequence's specific binding to a probe. The label also can be an enzyme, such as, alkaline phosphatase or horseradish peroxidase, which when provided with an appropriate substrate produces a product that can be detected. Alternatively, the label can be a labeled compound or small molecule, such as an enzyme inhibitor, that binds but is not catalyzed or altered by the enzyme. The label also can be a moiety or compound, such as, an epitope tag or biotin which specifically binds to streptavidin. For the example of biotin, the streptavidin is labeled as described above, thereby, providing a detectable signal for the bound target sequence. As known in the art, unbound labeled streptavidin is removed prior to analysis.

[0161] As will be appreciated by those in the art, these assays can be direct hybridization assays or can comprise “sandwich assays”, which include the use of multiple probes, as is generally outlined in U.S. Pat. Nos. 5,681,702, 5,597,909, 5,545,730, 5,594,117, 5,591,584, 5,571,670, 5,580,731, 5,571,670, 5,591,584, 5,624,802, 5,635,352, 5,594,118, 5,359,100, 5,124,246 and 5,681,697, all of which are hereby incorporated by reference. In this embodiment, in general, the target nucleic acid is prepared as outlined above, and then added to the biochip comprising a plurality of nucleic acid probes, under conditions that allow the formation of a hybridization complex.

[0162] A variety of hybridization conditions may be used in the present invention, including high, moderate and low stringency conditions as outlined above. The assays are generally run under stringency conditions which allows formation of the label probe hybridization complex only in the presence of target. Stringency can be controlled by altering a step parameter that is a thermodynamic variable, including, but not limited to, temperature, formamide concentration, salt concentration, chaotropic salt concentration pH, organic solvent concentration, etc.

[0163] These parameters may also be used to control non-specific binding, as is generally outlined in U.S. Pat. No. 5,681,697. Thus it may be desirable to perform certain steps at higher stringency conditions to reduce non-specific binding.

[0164] The reactions outlined herein may be accomplished in a variety of ways, as will be appreciated by those in the art. Components of the reaction may be added simultaneously, or sequentially, in any order, with preferred embodiments outlined below. In addition, the reaction may include a variety of X other reagents may be included in the assays. These include reagents like salts, buffers, neutral proteins, e.g. albumin, detergents, etc which may be used to facilitate optimal hybridization and detection, and/or reduce non-specific or background interactions. Also reagents that otherwise improve the efficiency of the assay, such as protease inhibitors, nuclease inhibitors, anti-microbial agents, etc., may be used, depending on the sample preparation methods and purity of the target. In addition, either solid phase or solution based (i.e., kinetic PCR) assays may be used.

[0165] Once the assay is run, the data is analyzed to determine the expression levels, and changes in expression levels as between states, of individual genes, forming a gene expression profile.

[0166] In a preferred embodiment, as for the diagnosis and prognosis applications, having identified the differentially expressed gene(s) or mutated gene(s) important in any one state, screens can be run to alter the expression of the genes individually. That is, screening for modulation of regulation of expression of a single gene can be done. Thus, for example, particularly in the case of target genes whose presence or absence is unique between two states, screening is done for modulators of the target gene expression.

[0167] In addition, screens can be done for novel genes that are induced in response to a candidate agent. After identifying a candidate agent based upon its ability to suppress a CA expression pattern leading to a normal expression pattern, or modulate a single CA gene expression profile so as to mimic the expression of the gene from normal tissue, a screen as described above can be performed to identify genes that are specifically modulated in response to the agent. Comparing expression profiles between normal tissue and agent treated CA tissue reveals genes that are not expressed in normal tissue or CA tissue, but are expressed in agent treated tissue. These agent specific sequences can be identified and used by any of the methods described herein for CA genes or proteins. In particular these sequences and the proteins they encode find use in marking or identifying agent treated cells. In addition, antibodies can be raised against the agent induced proteins and used to target novel therapeutics to the treated CA tissue sample.

[0168] Thus, in one embodiment, a candidate agent is administered to a population of CA cells, that thus has an associated CA expression profile. By “administration” or “contacting” herein is meant that the candidate agent is added to the cells in such a manner as to allow the agent to act upon the cell, whether by uptake and intracellular action, or by action at the cell surface. In some embodiments, nucleic acid encoding a proteinaceous candidate agent (i.e. a peptide) may be put into a viral construct such as a retroviral construct and added to the cell, such that expression of the peptide agent is accomplished; see PCT US97/01019, hereby expressly incorporated by reference.

[0169] Once the candidate agent has been administered to the cells, the cells can be washed if desired and are allowed to incubate under preferably physiological conditions for some period of time. The cells are then harvested and a new gene expression profile is generated, as outlined herein.

[0170] Thus, for example, CA tissue may be screened for agents that reduce or suppress the CA phenotype. A change in at least one gene of the expression profile indicates that the agent has an effect on CA activity. By defining such a signature for the CA phenotype, screens for new drugs that alter the phenotype can be devised. With this approach, the drug target need not be known and need not be represented in the original expression screening platform, nor does the level of transcript for the target protein need to change.

[0171] In a preferred embodiment, as outlined above, screens may be done on individual genes and gene products (proteins). That is, having identified a particular differentially expressed gene as important in a particular state, screening of modulators of either the expression of the gene or the gene product itself can be done. The gene products of differentially expressed genes are sometimes referred to herein as “CA proteins” or an “CAP”. The CAP may be a fragment, or alternatively, be the full length protein to the fragment encoded by the nucleic acids of Tables 1-10. Preferably, the CAP is a fragment. In another embodiment, the sequences are sequence variants as further described herein.

[0172] Preferably, the CAP is a fragment of approximately 14 to 24 amino acids long. More preferably the fragment is a soluble fragment. Preferably, the fragment includes a non-transmembrane region. In a preferred embodiment, the fragment has an N-terminal Cys to aid in solubility. In one embodiment, the c-terminus of the fragment is kept as a free acid and the n-terminus is a free amine to aid in coupling, i.e., to cysteine.

[0173] In one embodiment the CA proteins are conjugated to an immunogenic agent as discussed herein. In one embodiment the CA protein is conjugated to BSA.

[0174] In a preferred embodiment, screening is done to alter the biological function of the expression product of the CA gene. Again, having identified the importance of a gene in a particular state, screening for agents that bind and/or modulate the biological activity of the gene product can be run as is more fully outlined below.

[0175] In a preferred embodiment, screens are designed to first find candidate agents that can bind to CA proteins, and then these agents may be used in assays that evaluate the ability of the candidate agent to modulate the CAP activity and the carcinoma phenotype. Thus, as will be appreciated by those in the art, there are a number of different assays which may be run; binding assays and activity assays.

[0176] In a preferred embodiment, binding assays are done. In general, purified or isolated gene product is used; that is, the gene products of one or more CA nucleic acids are made. In general, this is done as is known in the art. For example, antibodies are generated to the protein gene products, and standard immunoassays are run to determine the amount of protein present. Alternatively, cells comprising the CA proteins can be used in the assays.

[0177] Thus, in a preferred embodiment, the methods comprise combining a CA protein and a candidate bioactive agent, and determining the binding of the candidate agent to the CA protein. Preferred embodiments utilize the human or mouse CA protein, although other mammalian proteins may also be used, for example for the development of animal models of human disease. In some embodiments, as outlined herein, variant or derivative CA proteins may be used.

[0178] Generally, in a preferred embodiment of the methods herein, the CA protein or the candidate agent is non-diffusably bound to an insoluble support having isolated sample receiving areas (e.g. a microtiter plate, an array, etc.). The insoluble supports may be made of any composition to which the compositions can be bound, is readily separated from soluble material, and is otherwise compatible with the overall method of screening. The surface of such supports may be solid or porous and of any convenient shape. Examples of suitable insoluble supports include microtiter plates, arrays, membranes and beads. These are typically made of glass, plastic (e.g., polystyrene), polysaccharides, nylon or nitrocellulose, Teflon™, etc. Microtiter plates and arrays are especially convenient because a large number of assays can be carried out simultaneously, using small amounts of reagents and samples. The particular manner of binding of the composition is not crucial so long as it is compatible with the reagents and overall methods of the invention, maintains the activity of the composition and is nondiffusable. Preferred methods of binding include the use of antibodies (which do not sterically block either the ligand binding site or activation sequence when the protein is bound to the support), direct binding to “sticky” or ionic supports, chemical crosslinking, the synthesis of the protein or agent on the surface, etc. Following binding of the protein or agent, excess unbound material is removed by washing. The sample receiving areas may then be blocked through incubation with bovine serum albumin (BSA), casein or other innocuous protein or other moiety.

[0179] In a preferred embodiment, the CA protein is bound to the support, and a candidate bioactive agent is added to the assay. Alternatively, the candidate agent is bound to the support and the CA protein is added. Novel binding agents include specific antibodies, non-natural binding agents identified in screens of chemical libraries, peptide analogs, etc. Of particular interest are screening assays for agents that have a low toxicity for human cells. A wide variety of assays may be used for this purpose, including labeled in vitro protein-protein binding assays, electrophoretic mobility shift assays, immunoassays for protein binding, functional assays (phosphorylation assays, etc.) and the like.

[0180] The determination of the binding of the candidate bioactive agent to the CA protein may be done in a number of ways. In a preferred embodiment, the candidate bioactive agent is labeled, and binding determined directly. For example, this may be done by attaching all or a portion of the CA protein to a solid support, adding a labeled candidate agent (for example a fluorescent label), washing off excess reagent, and determining whether the label is present on the solid support. Various blocking and washing steps may be utilized as is known in the art.

[0181] By “labeled” herein is meant that the compound is either directly or indirectly labeled with a label which provides a detectable signal, e.g. radioisotope, fluorescers, enzyme, antibodies, particles such as magnetic particles, chemiluminescers, or specific binding molecules, etc. Specific binding molecules include pairs, such as biotin and streptavidin, digoxin and antidigoxin etc. For the specific binding members, the complementary member would normally be labeled with a molecule which provides for detection, in accordance with known procedures, as outlined above. The label can directly or indirectly provide a detectable signal.

[0182] In some embodiments, only one of the components is labeled. For example, the proteins (or proteinaceous candidate agents) may be labeled at tyrosine positions using ¹²⁵I , or with fluorophores. Alternatively, more than one component may be labeled with different labels; using ¹²⁵I for the proteins, for example, and a fluorophor for the candidate agents.

[0183] In a preferred embodiment, the binding of the candidate bioactive agent is determined through the use of competitive binding assays. In this embodiment, the competitor is a binding moiety known to bind to the target molecule (i.e. CA protein), such as an antibody, peptide, binding partner, ligand, etc. Under certain circumstances, there may be competitive binding as between the bioactive agent and the binding moiety, with the binding moiety displacing the bioactive agent.

[0184] In one embodiment, the candidate bioactive agent is labeled. Either the candidate bioactive agent, or the competitor, or both, is added first to the protein for a time sufficient to allow binding, if present. Incubations may be performed at any temperature which facilitates optimal activity, typically between 4 and 40° C. Incubation periods are selected for optimum activity, but may also be optimized to facilitate rapid high through put screening. Typically between 0.1 and 1 hour will be sufficient. Excess reagent is generally removed or washed away. The second component is then added, and the presence or absence of the labeled component is followed, to indicate binding.

[0185] In a preferred embodiment, the competitor is added first, followed by the candidate bioactive agent. Displacement of the competitor is an indication that the candidate bioactive agent is binding to the CA protein and thus is capable of binding to, and potentially modulating, the activity of the CA protein. In this embodiment, either component can be labeled. Thus, for example, if the competitor is labeled, the presence of label in the wash solution indicates displacement by the agent. Alternatively, if the candidate bioactive agent is labeled, the presence of the label on the support indicates displacement.

[0186] In an alternative embodiment, the candidate bioactive agent is added first, with incubation and washing, followed by the competitor. The absence of binding by the competitor may indicate that the bioactive agent is bound to the CA protein with a higher affinity. Thus, if the candidate bioactive agent is labeled, the presence of the label on the support, coupled with a lack of competitor binding, may indicate that the candidate agent is capable of binding to the CA protein.

[0187] In a preferred embodiment, the methods comprise differential screening to identity bioactive agents that are capable of modulating the activity of the CA proteins. In this embodiment, the methods comprise combining a CA protein and a competitor in a first sample. A second sample comprises a candidate bioactive agent, a CA protein and a competitor. The binding of the competitor is determined for both samples, and a change, or difference in binding between the two samples indicates the presence of an agent capable of binding to the CA protein and potentially modulating its activity. That is, if the binding of the competitor is different in the second sample relative to the first sample, the agent is capable of binding to the CA protein.

[0188] Alternatively, a preferred embodiment utilizes differential screening to identify drug candidates that bind to the native CA protein, but cannot bind to modified CA proteins. The structure of the CA protein may be modeled, and used in rational drug design to synthesize agents that interact with that site. Drug candidates that affect CA bioactivity are also identified by screening drugs for the ability to either enhance or reduce the activity of the protein.

[0189] Positive controls and negative controls may be used in the assays. Preferably all control and test samples are performed in at least triplicate to obtain statistically significant results. Incubation of all samples is for a time sufficient for the binding of the agent to the protein. Following incubation, all samples are washed free of non-specifically bound material and the amount of bound, generally labeled agent determined. For example, where a radiolabel is employed, the samples may be counted in a scintillation counter to determine the amount of bound compound.

[0190] A variety of other reagents may be included in the screening assays. These include reagents like salts, neutral proteins, e.g. albumin, detergents, etc which may be used to facilitate optimal protein-protein binding and/or reduce non-specific or background interactions. Also reagents that otherwise improve the efficiency of the assay, such as protease inhibitors, nuclease inhibitors, anti-microbial agents, etc., may be used. The mixture of components may be added in any order that provides for the requisite binding.

[0191] Screening for agents that modulate the activity of CA proteins may also be done. In a preferred embodiment, methods for screening for a bioactive agent capable of modulating the activity of CA proteins comprise the steps of adding a candidate bioactive agent to a sample of CA proteins, as above, and determining an alteration in the biological activity of CA proteins. “Modulating the activity of an CA protein” includes an increase in activity, a decrease in activity, or a change in the type or kind of activity present. Thus, in this embodiment, the candidate agent should both bind to CA proteins (although this may not be necessary), and alter its biological or biochemical activity as defined herein. The methods include both in vitro screening methods, as are generally outlined above, and in vivo screening of cells for alterations in the presence, distribution, activity or amount of CA proteins.

[0192] Thus, in this embodiment, the methods comprise combining a CA sample and a candidate bioactive agent, and evaluating the effect on CA activity. By “CA activity” or grammatical equivalents herein is meant one of the CA protein's biological activities, including, but not limited to, its role in tumorigenesis, including cell division, preferably in lymphatic tissue, cell proliferation, tumor growth and transformation of cells. In one embodiment, CA activity includes activation of or by a protein encoded by a nucleic acid of Tables 1-10. An inhibitor of CA activity is the inhibition of any one or more CA activities.

[0193] In a preferred embodiment, the activity of the CA protein is increased; in another preferred embodiment, the activity of the CA protein is decreased. Thus, bioactive agents that are antagonists are preferred in some embodiments, and bioactive agents that are agonists may be preferred in other embodiments.

[0194] In a preferred embodiment, the invention provides methods for screening for bioactive agents capable of modulating the activity of a CA protein. The methods comprise adding a candidate bioactive agent, as defined above, to a cell comprising CA proteins. Preferred cell types include almost any cell. The cells contain a recombinant nucleic acid that encodes a CA protein. In a preferred embodiment, a library of candidate agents are tested on a plurality of cells.

[0195] In one aspect, the assays are evaluated in the presence or absence or previous or subsequent exposure of physiological signals, for example hormones, antibodies, peptides, antigens, cytokines, growth factors, action potentials, pharmacological agents including chemotherapeutics, radiation, carcinogenics, or other cells (i.e. cell-cell contacts). In another example, the determinations are determined at different stages of the cell cycle process.

[0196] In this way, bioactive agents are identified. Compounds with pharmacological activity are able to enhance or interfere with the activity of the CA protein.

[0197] In one embodiment, a method of inhibiting carcinoma cancer cell division, is provided. The method comprises administration of a carcinoma cancer inhibitor.

[0198] In a preferred embodiment, a method of inhibiting lymphoma carcinoma cell division is provided comprising administration of a lymphoma carcinoma inhibitor.

[0199] In another embodiment, a method of inhibiting tumor growth is provided. The method comprises administration of a carcinoma cancer inhibitor. In a particularly preferred embodiment, a method of inhibiting tumor growth in lymphatic tissue is provided comprising administration of a lymphoma inhibitor.

[0200] In a further embodiment, methods of treating cells or individuals with cancer are provided. The method comprises administration of a carcinoma cancer inhibitor. Preferably, the carcinoma is a lymphoma carcinoma.

[0201] In one embodiment, a carcinoma cancer inhibitor is an antibody as discussed above. In another embodiment, the carcinoma cancer inhibitor is an antisense molecule. Antisense molecules as used herein include antisense or sense oligonucleotides comprising a singe-stranded nucleic acid sequence (either RNA or DNA) capable of binding to target mRNA (sense) or DNA (antisense) sequences for carcinoma cancer molecules. Antisense or sense oligonucleotides, according to the present invention, comprise a fragment generally at least about 14 nucleotides, preferably from about 14 to 30 nucleotides. The ability to derive an antisense or a sense oligonucleotide, based upon a cDNA sequence encoding a given protein is described in, for example, Stein and Cohen, Cancer Res. 48:2659, (1988) and van der Krol et al., BioTechniques 6:958, (1988).

[0202] Antisense molecules may be introduced into a cell containing the target nucleotide sequence by formation of a conjugate with a ligand binding molecule, as described in WO 91/04753. Suitable ligand binding molecules include, but are not limited to, cell surface receptors, growth factors, other cytokines, or other ligands that bind to cell surface receptors. Preferably, conjugation of the ligand binding molecule does not substantially interfere with the ability of the ligand binding molecule to bind to its corresponding molecule or receptor, or block entry of the sense or antisense oligonucleotide or its conjugated version into the cell. Alternatively, a sense or an antisense oligonucleotide may be introduced into a cell containing the target nucleic acid sequence by formation of an oligonucleotide-lipid complex, as described in WO 90/10448. It is understood that the use of antisense molecules or knock out and knock in models may also be used in screening assays as discussed above, in addition to methods of treatment.

[0203] The compounds having the desired pharmacological activity may be administered in a physiologically acceptable carrier to a host, as previously described. The agents may be administered in a variety of ways, orally, parenterally e.g., subcutaneously, intraperitoneally, intravascularly, etc. Depending upon the manner of introduction, the compounds may be formulated in a variety of ways. The concentration of therapeutically active compound in the formulation may vary from about 0.1-100% wgt/vol. The agents may be administered alone or in combination with other treatments, i.e., radiation.

[0204] The pharmaceutical compositions can be prepared in various forms, such as granules, tablets, pills, suppositories, capsules, suspensions, salves, lotions and the like. Pharmaceutical grade organic or inorganic carriers and/or diluents suitable for oral and topical use can be used to make up compositions containing the therapeutically-active compounds. Diluents known to the art include aqueous media, vegetable and animal oils and fats. Stabilizing agents, wetting and emulsifying agents, salts for varying the osmotic pressure or buffers for securing an adequate pH value, and skin penetration enhancers can be used as auxiliary agents.

[0205] Without being bound by theory, it appears that the various CA sequences are important in carcinomas. Accordingly, disorders based on mutant or variant CA genes may be determined. In one embodiment, the invention provides methods for identifying cells containing variant CA genes comprising determining all or part of the sequence of at least one endogenous CA genes in a cell. As will be appreciated by those in the art, this may be done using any number of sequencing techniques. In a preferred embodiment, the invention provides methods of identifying the CA genotype of an individual comprising determining all or part of the sequence of at least one CA gene of the individual. This is generally done in at least one tissue of the individual, and may include the evaluation of a number of tissues or different samples of the same tissue. The method may include comparing the sequence of the sequenced CA gene to a known CA gene, i.e., a wild-type gene. As will be appreciated by those in the art, alterations in the sequence of some oncogenes can be an indication of either the presence of the disease, or propensity to develop the disease, or prognosis evaluations.

[0206] The sequence of all or part of the CA gene can then be compared to the sequence of a known CA gene to determine if any differences exist. This can be done using any number of known homology programs, such as Bestfit, etc. In a preferred embodiment, the presence of a difference in the sequence between the CA gene of the patient and the known CA gene is indicative of a disease state or a propensity for a disease state, as outlined herein.

[0207] In a preferred embodiment, the CA genes are used as probes to determine the number of copies of the CA gene in the genome. For example, some cancers exhibit chromosomal deletions or insertions, resulting in an alteration in the copy number of a gene.

[0208] In another preferred embodiment CA genes are used as probes to determine the chromosomal location of the CA genes. Information such as chromosomal location finds use in providing a diagnosis or prognosis in particular when chromosomal abnormalities such as translocations, and the like are identified in CA gene loci.

[0209] Thus, in one embodiment, methods of modulating CA in cells or organisms are provided. In one embodiment, the methods comprise administering to a cell an anti-CA antibody that reduces or eliminates the biological activity of an endogenous CA protein. Alternatively, the methods comprise administering to a cell or organism a recombinant nucleic acid encoding a CA protein. As will be appreciated by those in the art, this may be accomplished in any number of ways. In a preferred a embodiment, for example when the CA sequence is down-regulated in carcinoma, the activity of the CA gene is increased by increasing the amount of CA in the cell, for example by overexpressing the endogenous CA or by administering a gene encoding the CA sequence, using known gene-therapy techniques, for example. In a preferred embodiment, the gene therapy techniques include the incorporation of the exogenous gene using enhanced homologous recombination (EHR), for example as described in PCT/US93/03868, hereby incorporated by reference in its entirety. Alternatively, for example when the CA sequence is up-regulated in carcinoma, the activity of the endogenous CA gene is decreased, for example by the administration of a CA antisense nucleic acid.

[0210] In one embodiment, the CA proteins of the present invention may be used to generate polyclonal and monoclonal antibodies to CA proteins, which are useful as described herein. Similarly, the CA proteins can be coupled, using standard technology, to affinity chromatography columns. These columns may then be used to purify CA antibodies. In a preferred embodiment, the antibodies are generated to epitopes unique to a CA protein; that is, the antibodies show little or no cross-reactivity to other proteins. These antibodies find use in a number of applications. For example, the CA antibodies may be coupled to standard affinity chromatography columns and used to purify CA proteins. The antibodies may also be used as blocking polypeptides, as outlined above, since they will specifically bind to the CA protein.

[0211] In one embodiment, a therapeutically effective dose of a CA or modulator thereof is administered to a patient. By “therapeutically effective dose” herein is meant a dose that produces the effects for which it is administered. The exact dose will depend on the purpose of the treatment, and will be ascertainable by one skilled in the art using known techniques. As is known in the art, adjustments for CA degradation, systemic versus localized delivery, and rate of new protease synthesis, as well as the age, body weight, general health, sex, diet, time of administration, drug interaction and the severity of the condition may be necessary, and will be ascertainable with routine experimentation by those skilled in the art.

[0212] A “patient” for the purposes of the present invention includes both humans and other animals, particularly mammals, and organisms. Thus the methods are applicable to both human therapy and veterinary applications. In the preferred embodiment the patient is a mammal, and in the most preferred embodiment the patient is human.

[0213] The administration of the CA proteins and modulators of the present invention can be done in a variety of ways as discussed above, including, but not limited to, orally, subcutaneously, intravenously, intranasally, transdermally, intraperitoneally, intramuscularly, intrapulmonary, vaginally, rectally, or intraocularly. In some instances, for example, in the treatment of wounds and inflammation, the CA proteins and modulators may be directly applied as a solution or spray.

[0214] The pharmaceutical compositions of the present invention comprise a CA protein in a form suitable for administration to a patient. In the preferred embodiment, the pharmaceutical compositions are in a water soluble form, such as being present as pharmaceutically acceptable salts, which is meant to include both acid and base addition salts. “Pharmaceutically acceptable acid addition salt” refers to those salts that retain the biological effectiveness of the free bases and that are not biologically or otherwise undesirable, formed with inorganic acids such as hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid and the like, and organic acids such as acetic acid, propionic acid, glycolic acid, pyruvic acid, oxalic acid, maleic acid, malonic acid, succinic acid, fumaric acid, tartaric acid, citric acid, benzoic acid, cinnamic acid, mandelic acid, methanesulfonic acid, ethanesulfonic acid, p-toluenesulfonic acid, salicylic acid and the like. “Pharmaceutically acceptable base addition salts” include those derived from inorganic bases such as sodium, potassium, lithium, ammonium, calcium, magnesium, iron, zinc, copper, manganese, aluminum salts and the like. Particularly preferred are the ammonium, potassium, sodium, calcium, and magnesium salts. Salts derived from pharmaceutically acceptable organic non-toxic bases include salts of primary, secondary, and tertiary amines, substituted amines including naturally occurring substituted amines, cyclic amines and basic ion exchange resins, such as isopropylamine, trimethylamine, diethylamine, triethylamine, tripropylamine, and ethanolamine.

[0215] The pharmaceutical compositions may also include one or more of the following: carrier proteins such as serum albumin; buffers; fillers such as microcrystalline cellulose, lactose, corn and other starches; binding agents; sweeteners and other flavoring agents; coloring agents; and polyethylene glycol. Additives are well known in the art, and are used in a variety of formulations.

[0216] In a preferred embodiment, CA proteins and modulators are administered as therapeutic agents, and can be formulated as outlined above. Similarly, CA genes (including both the full-length sequence, partial sequences, or regulatory sequences of the CA coding regions) can be administered in gene therapy applications, as is known in the art. These CA genes can include antisense applications, either as gene therapy (i.e. for incorporation into the genome) or as antisense compositions, as will be appreciated by those in the art.

[0217] In a preferred embodiment, CA genes are administered as DNA vaccines, either single genes or combinations of CA genes. Naked DNA vaccines are generally known in the art. Brower, Nature Biotechnology, 16:1304-1305 (1998).

[0218] In one embodiment, CA genes of the present invention are used as DNA vaccines. Methods for the use of genes as DNA vaccines are well known to one of ordinary skill in the art, and include placing a CA gene or portion of a CA gene under the control of a promoter for expression in a patient with carcinoma. The CA gene used for DNA vaccines can encode full-length CA proteins, but more preferably encodes portions of the CA proteins including peptides derived from the CA protein. In a preferred embodiment a patient is immunized with a DNA vaccine comprising a plurality of nucleotide sequences derived from a CA gene. Similarly, it is possible to immunize a patient with a plurality of CA genes or portions thereof as defined herein. Without being bound by theory, expression of the polypeptide encoded by the DNA vaccine, cytotoxic T-cells, helper T-cells and antibodies are induced which recognize and destroy or eliminate cells expressing CA proteins.

[0219] In a preferred embodiment, the DNA vaccines include a gene encoding an adjuvant molecule with the DNA vaccine. Such adjuvant molecules include cytokines that increase the immunogenic response to the CA polypeptide encoded by the DNA vaccine. Additional or alternative adjuvants are known to those of ordinary skill in the art and find use in the invention.

[0220] In another preferred embodiment CA genes find use in generating animal models of carcinomas, particularly lymphoma carcinomas. As is appreciated by one of ordinary skill in the art, when the CA gene identified is repressed or diminished in CA tissue, gene therapy technology wherein antisense RNA directed to the CA gene will also diminish or repress expression of the gene. An animal generated as such serves as an animal model of CA that finds use in screening bioactive drug candidates. Similarly, gene knockout technology, for example as a result of homologous recombination with an appropriate gene targeting vector, will result in the absence of the CA protein. When desired, tissue-specific expression or knockout of the CA protein may be necessary.

[0221] It is also possible that the CA protein is overexpressed in carcinoma. As such, transgenic animals can be generated that overexpress the CA protein. Depending on the desired expression level, promoters of various strengths can be employed to express the transgene. Also, the number of copies of the integrated transgene can be determined and compared for a determination of the expression level of the transgene. Animals generated by such methods find use as animal models of CA and are additionally useful in screening for bioactive molecules to treat carcinoma.

[0222] The CA nucleic acid sequences of the invention are depicted in Tables 1-10. The sequences in each Table include genomic sequence, mRNA and coding sequences for both mouse and human. The different sequences are assigned the following SEQ ID Nos:

[0223] Table I (mouse gene: Fscn1; human gene SNL)

[0224] Mouse genomic sequence (SEQ ID NO: 1)

[0225] Mouse mRNA sequence (SEQ ID NO: 2)

[0226] Mouse coding sequence (SEQ ID NO: 3)

[0227] Human genomic sequence (SEQ ID NO: 4)

[0228] Human mRNA sequence (SEQ ID NO: 5)

[0229] Human coding sequence (SEQ ID NO: 6)

[0230] Table II (mouse gene Map3k6; human gene MAP3K6)

[0231] Mouse genomic sequence (SEQ ID NO: 7)

[0232] Mouse mRNA sequence (SEQ ID NO: 8)

[0233] Mouse coding sequence (SEQ ID NO: 9)

[0234] Human genomic sequence (SEQ ID NO: 10)

[0235] Human mRNA sequence (SEQ ID NO: 11)

[0236] Human coding sequence (SEQ ID NO: 12)

[0237] Table III (mouse gene Fosb; human gene FOSB)

[0238] Mouse genomic sequence (SEQ ID NO: 13)

[0239] Mouse mRNA sequence (SEQ ID NO: 14)

[0240] Mouse coding sequence (SEQ ID NO: 15)

[0241] Human genomic sequence (SEQ ID NO: 16)

[0242] Human mRNA sequence (SEQ ID NO: 17)

[0243] Human coding sequence (SEQ ID NO: 18)

[0244] Table IV (mouse gene cmkbr7; human gene: CCR7)

[0245] Mouse genomic sequence (SEQ ID NO: 19)

[0246] Mouse mRNA sequence (SEQ ID NO: 20)

[0247] Mouse coding sequence (SEQ ID NO: 21)

[0248] Human genomic sequence (SEQ ID NO: 22)

[0249] Human mRNA sequence (SEQ ID NO: 23)

[0250] Human coding sequence (SEQ ID NO: 24)

[0251] Table V (mouse gene: Ccnd1; human gene: CCND1)

[0252] Mouse genomic sequence (SEQ ID NO: 25)

[0253] Mouse mRNA sequence (SEQ ID NO: 26)

[0254] Mouse coding sequence (SEQ ID NO: 27)

[0255] Human genomic sequence (SEQ ID NO: 28)

[0256] Human mRNA sequence (SEQ ID NO:29)

[0257] Human coding sequence (SEQ ID NO: 30)

[0258] Table VI (mouse gene: Ccnd3; human gene: CCND3)

[0259] Mouse genomic sequence (SEQ ID NO: 31)

[0260] Mouse mRNA sequence (SEQ ID NO: 32)

[0261] Mouse coding sequence (SEQ ID NO: 33)

[0262] Human genomic sequence (SEQ ID NO: 34)

[0263] Human mRNA sequence (SEQ ID NO: 35)

[0264] Human coding sequence (SEQ ID NO: 36)

[0265] Table VII (mouse gene: Wnt3; human gene: WNT3)

[0266] Mouse genomic sequence (SEQ ID NO: 37)

[0267] Mouse mRNA sequence (SEQ ID NO: 38)

[0268] Mouse coding sequence (SEQ ID NO: 39)

[0269] Human genomic sequence (SEQ ID NO: 40)

[0270] Human mRNA sequence (SEQ ID NO: 41)

[0271] Human coding sequence (SEQ ID NO: 42)

[0272] Table VII (mouse gene: Batf; human gene: BATF)

[0273] Mouse genomic sequence (SEQ ID NO: 43)

[0274] Mouse mRNA sequence (SEQ ID NO: 44)

[0275] Mouse coding sequence (SEQ ID NO: 45)

[0276] Human genomic sequence (SEQ ID NO: 46)

[0277] Human mRNA sequence (SEQ ID NO: 47)

[0278] Human coding sequence (SEQ ID NO: 48)

[0279] Table IX (mouse gene: Irf4; human gene: IRF4)

[0280] Mouse genomic sequence (SEQ ID NO: 49)

[0281] Mouse mRNA sequence (SEQ ID NO: 50)

[0282] Mouse coding sequence (SEQ ID NO: 51)

[0283] Human genomic sequence (SEQ ID NO: 52)

[0284] Human mRNA sequence (SEQ ID NO: 53)

[0285] Human coding sequence (SEQ ID NO: 54)

[0286] Table X (mouse gene: Notch1; human gene: NOTCH1)

[0287] Mouse genomic sequence (SEQ ID NO: 55)

[0288] Mouse mRNA sequence (SEQ ID NO: 56)

[0289] Mouse coding sequence (SEQ ID NO: 57)

[0290] Human genomic sequence (SEQ ID NO: 58)

[0291] Human mRNA sequence (SEQ ID NO: 59)

[0292] Human coding sequence (SEQ ID NO: 60) TABLE I MOUSE NOMENCLATURE ICSGNM      Fscn1 Celera      mCG23208 HUMAN NOMENCLATURE HGNC        SNL Celera      hCG15970 MOUSE SEQUENCE - GENOMIC CCTCTCAAACTCTTGGTAATTCTCCTGCTTCGGCACGCTGGGGACTGGGACTACACCTGTGTGCCACCATGGCTGGCTATTTCTCTCTCTTGAACAC TGGAAGAGTGCTCAGAGTTTACTGGATCTGGGAGAAGCTCGAGGCTGGGTTATGGAAGCCGGCTCTGCTTGCTCCAGCTCAGGGAGGAGTTGCCTGA GGGCCAGGCACTTCGAAGGACAGATGGGACCCAAGGCCAGACACTGGGCCCCAGCTCACCAGAAGTGGAGCCCTGACTGTCTCTGAGAGGGTAAGCT GGGGTGGCTGCCAGGCGGGCAAGGCCAAAGCCTGGCAGCAGCCGGTGGCCCCTCTTCTGGCAGAGATATCTTGGCATGAGCCTGGCTCTGCCCATGA CACTAAAGTGCCCTCTTAATTAGCCAGGCTCTTGCCAAGCACTGGCCACGATTGCCTTGTTTCACAGAATTCACCTTGGACTGGCACAGATGGGGAG GGTGGATAGCCCGGTGTTTTGTCTTTCTTCTAGGGGAGCTGGGCTCAAGGGCAGGACTCCTGGGCCAGCCCAGGTTTTTCCCTCAGAAACCACAGCA TGAATACTGGCATGATGGAGCACACCTGTAATCAGCAGAAATTGAGACAGGAAGATTGTTGAGAATTTGAGGCCAACCTAGGCTAAATAGGGAGACC CTATCTCTACACACTCCCCCTCCCCCCGCCCCTGGAAATGCTGGAGGGTCTGGGGAAGATGGCTCAGTGGTTAAGGGCACTTGCTGCTCTTGCAGGG GACCCAAGTTTGATTCCCAGCATCTATAACTTGGTGGCTCACAATTCCAGTTCCAGGCACTCTGACACCTTCCTGTGGTCTGCAAGGCACCTGCATT CATTCTCACGTGCATGCGCACACACATGCGCGCGCGCACACACACACACACACACACACACACATCTCATAAATACAAATAAAATAAATCTTGAAAA CAACAGTGACAACAACACATGCTGAACATGGTGGTGCTCCTGACATGGTGGTGCTCCTGACATGGTGGTGCTCCTGACATGGTGATGCTCCTGACAT GGTGGTGCTCCTGACATGATGGTAAGCCTGACATGGTGGTGCTCCTGACATGGTGGTGCTCCTGACATGGTGATGCTCCTGACATGGTGGTGCTCCT GACATGGTGGTAAGCCTGACATGGTGGTAAGCCTGACATGGTGGTGCTCCTGACATGGTGGTGCTCCCTGCACTGACAGTTCTGAGGAGGTGGAGAT AGGAGGATCCAGACTTGGAAGCTTGCCTGAGATAGACCCTGTCTCAGAATAGGCTGGAGGCTGCCTCTGCCCTTTTGCTTCTATCTCTTTTTCCATA TGTGTGTGTGCGTGTGTGCATATGTGTATGCATATTTGTAAGTATATGTATATAAATAAACACACACACACACAAACTTACTCTGTATACTAGGCTG GCCTTGAACTCAGAGACCTGCCTGTTTCTGCCTTCCCAGTGCTGGGATTAAAAGCGTGTGCCATGGGCTGGTGAGATGGCTCAGTGGGTAAGAGTAC CTGACTGCTCTTCCAAAGGTCCAGTGTTCAAGTCCCAGCAACCACATGGTGGCTCACAACCATCCGTAACAAGATCTGACGCCCTCTTCTGGTGTGT CTGAAGACAGCTACAGTGTACTTAAATAAATAAATCTTAAAAAAAAAAAAAAAAAAAAAAAAAGGCGTGCACCACCACTGCCCGGCTAGTTAGCTTT ATCTTCCGTGGATGTTTTGTCTGCAGTATGTCTGAGTGAGGGTGTCAGATCCTCTGTAACTGGAGTTATAGACAGTTGTGAGCAGCCATGTAAGTGC TGGGAATTGAATCCGGGTTCTCTGGAAGAGCAGTTCATGCTCTTAAGCACTGCGCCATCTCTCCAGCTGTCCTTATTTATTTTTAAGGGTCTCTTGT AGCCATACAGGCCAGAAACCCACCATTAGCCACGGACCTTGAGCTCCAAGTGCTGGGTGACAGGCCCGCATCTCTCCTGGTTTGTGATCTGCTAGGG ATGGGGTCTAGGACCTCACACAGGCTGCATAAGCATTCCCCTCACCCACCCTCATCCCCACCCAGTCCTGGACAGGCTCTGGCTGTGTAGGCTGGTC TCCTCCTTTCTATCCCCCTGCCTCAGCCTCCTGAGTGCTGAGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTGTGGTGGCTCCCGAGTGCTGTCATCCCAGCACTGGGGAGGTTGAAGCAGGAAGGAGAATCACAG GTTCAAGGCCAGCTTGGTTTACTTGAGACTCTGTCTCAAAAAGACCAAACCAGGGACTGGGAGGATGGCCAGTAAAATGCTTTTCCAGCTATCGAGG GAACCTGAGTTTCATCCTGGAACTCATACAAAAAGCTGGCTGTGGTCAGGTGGCGCATGCCTTTAATCCCATCACTCAGGAGACAGAGGCAGGCAGA TTCTTGAGTTCGAGGCCAGCCTGGTCTACAGACTGAGTTCCAGGATAGCCAGGTCTACACAGAGAAACCCTATCTTGGAAAACAAAACAAACAAAAA AAACTAGGTGTGGCTAGCCTGTAACCCCAGTGCTGGGTAAACAGGGGCAGGTGAATACATCTCCGGGATTCGCCAGCCTGTCCTATCTATGAGCTCT AGGTCTGGGGAGACAGCCTGTCAAATCAATGCAAGCAGGTGACAACCGAGGAAAGACACCCAAGGTTGATGCACGGGCAAGTGTGCACACACACACA CCACAGCAAACAAAAACTAACAAAACCCAAACCATATTTTGCTGTGGTGGTGGTTGTTAAATTTTATTTATTCTGTGTGTATGGGTATTTCACCTGC ATGAATATCTACCTGTGTAGCATATACATGCCGGGTACTTTCGGAGGTCAGAAGAGGACATCAAATCCCGTAGAACTGGAGTTACAGAAAATGAACT TGTGGCTTCTGGGAATCTAACTTGGATCCTCTAAAGGACAGGCAGGACTCTGAATTCTTGAGCCACAGATACAGCTTTCCAAACCCATGTTTTGTAA GAGCCACCAGGCCTGAAAACTCTGGGCCATGTCCCGTTTGTTGTGTCTAGGCCTCAGTTTCCTGGAAGGCAGAGAATGCGTAGGTCCGTTGTTAGTG GAGACAGCAGTGGTGGTAACAGCCTGGTCTACCCTCTTGGTCAGAGGGAGGCAGGCGGAGAGTAACTCAGGGCCTGGGGGCAACACCCAGCTGGGCC TGGGGCTAGTGGGGGCTCAGCCAGGCAGGACGTGGGTCCTCCTACTTCCTAAGCTCTGATGGGCAAGTGGTGCCAGTGGTACCAGGCTGCCCTGAGG GGCCCTTAGAGCAGGTGACCACAGAGCCACAAAGAGGCTATTCATGGCCTCCGGTTCACGAGGCTGCCCCTTTATTGAGGGCTTGAACCACAGAAAG CTGTGTGGTCTGCAGGGAAGCTAGTTCTGAGCTGTCTGGCCAGCTACAGTAGTGTGTGTGTGTGTGTGTGTGTGTATACACATGGTACTTTTTTCTA TCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTTTGTGTCTATGTATCTAATAATAAATTGATCTATTTAACTATGTAG ATATCAATCCATTGATCTATGTATCTATCAACTGATGTGTATGTATGTATGGATGTACCTACATGCGTACTTGAGGCAGGACTTAAAGTAGCCCAGG CTAGCCTTACCACATTTCATAGCAGAGGATGGTCTTGAACTTCAGGTCCTCCTGTCTCTACCTCGTGAGTGCTGGGATTACAGGTTTGTGCCACCAC GCCTGGCTTAGGAGGTTCTGTGGTTAGAATCCAGGATTTCACTATCAACTGGGCCACATCGTCAGCCATATTCAATATGCTTTCTTTTACATTCTTA CTTATTTACTACAAATGGGTCCCAGGAACCAAGGTCGGCAAGCCTGATGGTGAGTGCTCTTCCCTGCTGGCTGACTTATTTGCTCTTTTTTTTTTTT TTTTTTTTTTCTAGACAGGGTTTCTCTGTGTAGCCCTGGCTGTCCTGGAACTCACTTTGTAGACCAGGCTGGCCTCGAACTCAGAAATCTGCCTGCC TCTGTCCCCAACCCCACCCCCAGTACTGGGATTAAAGGCATGCGCCACACGCCCAGCTCTTATTTGCTCCTTTGAATTAAGGTCTCATGTACACAAG GCTGACCGTTCATGCACAATACAGCTAAGGCTTGCTTTGAATTTCTCAGTTTCTTTCTTCTACCCAACAGTTTCTGAGATTTCAGGTCCGTCCTATG TCATGCCCAGGTTTTTTGTTTGTTTGTTTGTTTGTTTTTTGGTTTTGTTTTGCTGTTTTTCAACACAGAGTTTCTCTGTGGAACCCTGGCTATCCTG GAACTCTGTATACCAGGCTGTCCTTGAACTCAGAGACCCTCTGCCTCCCTAGTGCTGGGTTAAAGGTCCCTGCCATCACCGTGAAACTTAAGCCCAG CTTCTCATTTGGTGGCTGGAAATTTGCCTGCCTCTGCCTCTCTCCAGCTGCCTAGCACTGATGTCTGGTTGAGAGCAGGGGAAACTGAGGTGCCGCT AGGACAAGATCTCATGCAACCGTGAACAGCCCTACTGAGCCATCCTCCTGGGACAGCCTCTCAGGCCAGGCCTTCTGTGTCTTCTGCTATAGTAGCA GTACAAAGTTGACACAACCTTGCTCTTCCCAGCAGCTGGGAGTTCCTGAGAAGTGTAAATGAGGTTTCCAGGAAAGCCAAGAGGTGAGAGACTGAAA AGTTGGAGGGATAAGGGGGTGCCCATCAAGCTGCAGTGGAGACTTGTTATCTGTTGCGCATCCCTGACATCTCAGCAGGAGGATCAGGAGTTCAAGG GCATCCTCAGCAACATAGTAAGTCTATGGAGCTAGCCTGGGCTACACAGATGCCATTACAAAAAAAAAAAAAAAAGTAAAAAAAAAATCTTGGGATA TGGGGGATGGGTGGGTGAACTGTGTAGCCCAGGGAGTCACTACTGGTTCCTTTGGAAGTCCCTGTTCTGCATGGAGATCATGGAGATTCTGGGGACA CTCCAGGAGTCCTCCTTCAGGGAACTAAGTTGGGGAGCAGGGCAGCCTATCCTGTGGCCTTATTTCCTGTCTGGTGCAAGCGCCAGGCAAGGCATCC AGCCAGGAGCGACTCAGGCCTGACCTCCGCTAACTGTTCTGTTTTGTGCTGCACCCTCATCTCAGCAGGGATCAGGTGGCACTTGGGTCCCCAGGGG ATCCAGGGACACAGTGTCCATGTCCCCATCTTTCCCCACAGGGACCTGGGGCAGGGCCGAAGAGGAGACCTCGTGATGTGTACAGGTGTAGCTCATC CCTCCGAGGACTCAGGGGACACTTGGGGAAGGTGTGACACAGAGCAGGCTGGAGCTCTGTGCGGCTCTTTATTAAGTGTGCCTACAACAGGGGCAGA GACACAGCAGCGACAATGATAACAGCCCACTCCCAACCGAAGCTCAATGGTTACCAGACTCAGCCAACTGCAGAATTCCAGTCCATAACGGCACCTC CTTTCCTTTCTCAGGAGCTTACCAGAGAGGTCTCACCCCAAGCCTTCACCCCATCTAGAGCAAATGCTTATATCCCCCATGTTTGCTCAGAGCAGAG CATGGAGGGACCTTCCTGTCACCAGAGGCAGAGGCATTCTGTATACGTGCATACACGCCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTGGT ACAGATCTAAGCATAGAAAATTGAAAAGCATTGAGGTTGGTGATTGAAAGGCTCACTGATGGGCAAGTCGGGTTCGAGTGCGCTAACTGTATGACTC TATGGATCCGAATATCATGCTGTTTTGGAAAGGAATGAGGGAGCTACTGTTTCTAAGGAAGAGAAGAATGGGCACCAAGACATAGGGAGGGAAGGTG GGACAGTAAGCACTTACAGCCGAAGCCCAAGACCTGGAACCCAAGGGGAAAAACAGGTGTGGCCAGGCTTGGTGGCACGCGCCTTTAGTCTCTGAGT TCAAGTCCAGCCAGGATTACATAGCAAAACTTTCCCTCAAGAAAAAAGGTAGGGGCTGGAGAGATGGCTCAGCAGTTAAGAGCTCTTCCGAAGGTCC TGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCTGTAATGAGATCTGACGCCCTCTTCTGGTGTGTCTGGAGACAGCTACAGTGTACT TACATATAATAAATAAATAAATCCTAAAAAAAAAAAAAAAAGAAAAAGAAAAAGAAAAAAGGTAGAGGAGGAGGAAGAGGAGGAGGAGACGGCAAGA CAAAACTAACTACATAGCTGGGGGAGGTGGTGCTTGCCTATAATCCCAGCACTTGGAAGGCTGAAAGAGGAAATCAGGAGTTCCTATGCAGCTTTGG CTTATGTGAGCCTTTCTCATAAAACCAAGAGCAAAAAAGCAAAACATGAGGTGGTAACTCAGCTGGAGAGTGCTTGTCTAGATTCCCTCAGTGAGGG GCTGGGGTGTGACTCAGTGCCTAGAATCCCCCAGGGAGGGGCTGGGGGCGTGGCTCAGTGGTAGAGCCCCTGCCTAGAATCCCCCATTGACGGGCTG GGGTGTGGCTCAGTAACAGACTGCTCACCTAAGATGTTCAAGGCCATGACTTTCATTGAAAACATCACAAAACAAACAAAACCATCAGTGAGGTTGA ATGTGTATCCATGTTTGCTTGTCTCCATTTAAAGAACACCTGGAAGATCTCTAGCTGCTGGTGGAGGCGGGAGGGTGAAGGCTGCTTCATCCTTTGT ATTTGAACTGTGTGGCTGTGGGTGTATTATCTGTTCCCAAGGACTGCACATGAAATGAGAACAATGAAGGCTTCGGTTCTGCTGAGATGAACCTCAA TTCTCCACAGATGATCTCACCCAGAGCCAGATGGAAGTCCCCCAACATTTAAGCCTCTGTTCTGAGTGCTGGACCCAAACTCATCTTAAGGGAAAAC CCAAAGAGCCTTTCTGTGGTTTCCTTCCACAACTGTCTTTCAATGTGTGTATGTGTGCACGTGTGTTTGCTTGTGTGTGTGTGTGTGTACTATGTGC ATGTGTGTGAGCATGTGTGTATATGTATGTGCATGAGTGTGTGTGTGTGTGTGTATACATGTGAGCATGTATGTATAGGCCAGAGGTTAGTGATGGG TAACTTTCTCCAGAGCTCTCCACCTTAGTTTTATTGTCTGTGTGTGAGCGGCTGTGGGCACTGTACACCACAGCACATGTGTGGAGGTCAGAGAACA ACTTGTGGCTGTCACTTCTCTCCCTCTGTGTGGGTCTAAGACCTGGATCCAGCGCTTTCGCTTGCTTGAGACATCTCGTTGACTAGCTCCTCCGTTG TTAACACAGGGTCTCACTATGTAGGTCCAGTTATCTTGGAATTTGCTCTGTAGACCAGGCCGGCATCAAACTCAGAGATAGACCTGCCTTTGCCTCC AGAGTACTGGGATTAAAGGTGTGCACCACTACCACCCAGTTTAAAATTCTAAAAAGATTTGTGGGTGCAGGGATTTGAGGAGGCCAGGAGAGACTGT TGGATCTCTGGGAACTGGAGTTAGAGGTGGTTGTGAGCCCCCACGGGTGCTGAGAACTGAACTAGGGTGCTTGAGAGGAGCTCACTCACTGCTGAGC CCCCACTTTAGATTTGAGTCCCTCGTACTGAAGCTGAGTTCAGTGATTTGGCTGAGCTGACCGCTCAGGGTGGGCTTTTCGATGTGCACCACAGGCC TGGCTTTATAGGTGAGGTCATGCTTGCACAACTGGCCTTTTGGTGACTCAGCCAACTCCCCAGACCTTTTTTCTTTTGCATTTACGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACATGAAGTGAGAGGGGGCAGTCTGGGAAGGGTCAGTGGACAACTTAAGGGAGTTGGTTTTGCCTTC CATCATGATGGTCTAGAGACTAAATTCAGCCCCTCAGCCTGGGAGCGTGCCTTTACCCTCCGAGCTCCCAGCTTTGGGTTTTTGAGGCAAGGTTTCA TATAGCTTAGGCTGGCCTGGCATTCAAGGTCATCTCAGAGGCCTAGGATGACCTTGTGTTGTCCGTTCTCCGGCCTTTACCTCTGGTGTGCTGGCGT TTGCCTTACCACACCCAGGCATCCCCCATAGCTTAAGCCTAAAGCTCTCGGATGGCCAGCACGCCCATGCCCTGACGTGAAGTTCAGTGACTAATCA ATACAGAGCGTTCACGGAGCCCTGACACATAGCAGCATTGACTTAACCTTAACAGCCTGGTGTGTAATGAGGCCAACTTGTCCGATTCTGCCCACGA TGCGATGCTCTGGGTTAAACAGGTTTGAACAGAGTACCGGATGGCAGGGAGGGCACCCTCAGTACAGGGTTTTGGCTGTTACTGCTTCCAGTCTCCT GACCTGCTCCCCCAAGGCTGGTCTTAAACTCAAAGCAATCCTCCTGTCCCTGCTTCTCAAGTTCTGGAATTACAAGTGTGACTCACTGTACCCAGGA ATATGTGTCTTTATTACAGAGGAAGGAGAGCTCAGAGAGTGAGAGTAACCTGTGCAAAGTCCCACAGCAGGAGAGGGTGGCTGGCTATCGGCCGTGA ACTTGGTGACCTTTCCTGTGACCTCTAAGGGAGGAACTAGATGTCCCAGCAAGGATTCTAGGGACTTGTCAGGACTGACCTTTGATGATGGGAAAGC CATGCCATCTCCCCTTCCCCTTTGATGGTCGCTGGAGGGGTTTGCCTGGGACAGAGATGTGTTTGGACACAGATCACCGTGAAGACTGGTCAGTTTC AGTACCCTGCCCAGCCTGTGGCTGGGAAGGGCCAGGGGCCCAGATCTTGTGGGCAGCCTGGGGTAGGGCCAGCATTCCAGGGGCCTGCCTGGCATGT GGGGAATGTCCCAGGAGAAGTCTCAGTCCTCCAGAAACTCAAAGGGAAGTGTTCTTACGTGGGGTGGTGTGTGGTGGGAGGTGGGAGGTGGTGTTTG TGGGAATGTCCCTCTGGTCTGGAACCCTGAGGGGCTGCAGTTAGGAGGTACATTGGGGCTGTGCCATTCTAGGGAGCTGACCTGCTTTTCTGATGTC TTCATAAACAGAGACCACTATTCCTGCCTTACCTACCCTGCTTCCTGGTAGACCAGCACCCCGGGGCTTGAGCATCACCACAGTAGGGACTTTTGTG GGCCACTGACTTGGGCCACAGTTACCACAATTTATTTAGAGTCAGCAAGGTGGCTGTACTCTATGCTGACCCGGGAATAGAAATCTCGGTTTCTGCT CAGGAGGCCCAGGCTACAAGGCCTTGAAAAACCCTGAGGCGGGCGGGGCAGGTAGGGCTCTGCATGCGCCTCTCTAGAAATTAACCTCCTTTCTACC CCAGACCCTTCTGGCGTCTCTGGCTTCTTCAAGGACCGGCTCTAAGGCTACTTCCTGGTACACCCTGGACCCTCCCTCCATCCTGAAGGGATCATTA TCTTAAACCTGGTCCTTCCCATCGACTGGGTTTGGGGGTAGGGGTGTTTCAGGATGGCCTCAGAGAGCAGGAGAAAGTTGGAGATCAGCCAACTACT GCAGAGCACGACTGTGGAGGAACAGTTAAATGGACTAGCAAACACGAACGGGCCAGAGGCAGAAGGACTGCTATGAGTTCGAGTCCAGCCTGAGCCA CACAGATACTTCAAGCCTAGTCTGAGTTACAGAGTGAGACCCGGTCTTAAACCCCAGAAAAACACTCCGGGGAAGCGCAGGGGACCGGGCGCGCGCT GCAGAGCCCCCTCCCCGGCAGGCCCGGGTAGGGGCGTGGCCACGGTGACGTCATCCTCCTATAAAACCCTGGGCGCCGCCGGGCTGGCTTTGTGGAG AACTGCAGCGGGCTAAGCCGTGTTGAACAAAGGAGGTCGGGCACAGCTATCCAAGCTCCCGGGGCCACCGGGCCGCCCTCCGCCACCATGACCGCCA ACGGCACGGCAGAGGCTGTGCAGATTCIGTTCGGGCTCATCAGCTGCGGCAACAAGTACCTGACAGCCGAGGCGTTCGGGTTCAAGGTGAACGCATC CGCTAGTAGCTTGAAAAAGAAGCAGATCTGGACGCTGGAGCAACCTCCCGATGAGGCGGGCAGCGCGGCCGTGTGTCTGCGCAGCCACCTGGGTCGC TACCTGGCCGCCGACAAGGACGGCAACGTGACCTGCGAGCGCGAGGTGCCCGACGGCGACTGCCGCTTTCTCGTCGTGGCGCACGACGACGGCCGCT GCTCGCTGCAGTCCGAGGCTCACCGGCGCTACTTTGGCGGCACCGAGGACCGCCTGTCCTGCTTCGCGCAGAGCGTGTCGCCGGCCGAGAAGTGGAG CGTGCACATCGCCATGCACCCGCAGGTTAACATCTACAGCGTTACCCGCAAGCGCTACGCGCATCTGAGCGCGCGGCCGGCCGACGAGATCGCGGTA GACCGCGACGTGCCTTGGGGCGTCGACTCGCTCATCACCTTGGCCTTCCAGGACCAACGCTACAGTGTGCAGACGTCCGACCACCGCTTCCTGCGCC ACGACGGGCGCCTTGTGGCACGGCCGGAGCCCGCCACGGGCTTCACGCTGGAGTTCCGCTCCGGCAAGGTGGCCTTTCGCGACTGCGAAGGTCGCTA CCTGGCTCCGTCCGGGCCCAGCGGCACCCTCAAGGCTGGCAAGGCCACCAAGGTGGGCAAAGATGAGCTCTTCGCCCTGGAACAGAGCTGCGCTCAG GTGGTGCTGCAGGCGGCCAACGAGAGGAACGTGTCCACGCGCCAGGGTGAGTTGGGGACATGTCCCCTCCCTTGGGTCCTGACCCAGTGCACAAAAG CATCTCTGCACTCCTTCTATTTCCCTATTTCCTCCTGGGCTCCCTTTAGGCTCACAGGCCTCTGGGCTCCGCCATGGGGAGGTGGGCTTCTATTTTG AAAGACCTGATCTCACCAGATAGCCTTGGCTATCCTGGAACTCGCTATGTAGACTGGGCTGGCCCCGAACTCGCAGAAATCTTCCTTCCTGTCTCTT GTGCTGGGAATAAAGGCATGTACCACCCCTCTGTTCAGGACGTAGGCTTCTTCTGCTGGGAGAAGGTGACGTGGGGAAGTGGGTAAGGCCTAACACA TTCTAAAGCAATACTGTCCACCACCACCCCCCCACCCCCCCACCCCCCCGGCTGGGGGCGTGGGACTCCATAGACCTAGCTTAGATCTTCTCCGTTT CCTCTTCCTTCCCAGTCTGAGCCATCCCCATTCATGAGCCGATTCTTTAGGATAGGCTGTCCCAGGTCTTGGAGAGGAAGGGTTCCCCCTACACCCC CCCTTGTTCATTTCCTCGTGCGTCCTCTCCCGTTTCGCGGGCCTTTGGCTGGAGGGCCAGGGGACAGTCACCCCTGCCCTCCCCGCCTTAAATGGCG AGATAGAGGAGGTTGGAGGGGCTTTTGATCCCGGCGGGGTGTGCTGGGCGGGGTCGGCCCTGCGACTCTTGGTGGTGGTGGGGTTGTCCGTAGGGGC TTCCCCTCCCCCACTCCATCTCCCCTCGCTAAGGCCTGGCGCTCCGGGCCGCGGCCTTTGTGAGCAGGGGGGCGGGTCGCCACGGCTGGGCCCTCCC TCGTCCCCTTTGTCCTGCTAAGGCTCTGCAGATGGGAAAACCAGATGCGGCGGAGCTGGGGGAGGGGATCGGCTTAGGCGGGTCCCTCTGCGGAAGA GCCACCCCCAACCCTCCAGGCGTTGTCCCTGGTCCAGGGTTCATTGAGAAGGCGCGGAGTGAAGCCGCCTGGCTCTTCCTTCGCACCCCGGCTGGCA GGCGGCGTGGCGCGGGTGGCTGCGCGCCAGGCGCCCTCCCTGCCCTCCTATGCACGCCTTGCGGTCCGGCACTCGGCGGAGTGTCCCTCCAAAAGCC TCTACTCTCGAGTGAACCGGTCCCCAAGGCCTCTCTGGCTGGGAACAACCGTTTGCAGCTCTATTTGTCCCCATCCAGGGCCTCCAGCAGGCTGGCA GGCCATTTCCGACCGGCATGGGCATGGTACAAGTAGGCGCCTCCTTTCTGGCGTACCCCCGACTCTTCAAAGGGTCTTTGCTGCCTGCTGGTAGGGG CTTGTGAGATCTCGCTTCCTTGGTTGGGAAACTGAACCCCAGGCTTTGGAGATAGCTGGATGGGAGCCAGTCTGTGGGGAGGAAGACCCCCCTCCCC CAATGCAGAGGGCAAAGCCTTGGGTGGGGCCTGCTTGAGTTTGGCTGAATAACGCTCAGAAAAGTGCGACCATTTGCTTACTGTTACACAGTAAGTC AGCACCATGCTGAACTGGGTGTACTTGATGCCAGAATGTTCTCTCATTATACACACACACACACACACACACACACACACACACACACACCAATGAA CCATGGCCTCTCTTGTTTCACAGTGCTGGGCGAGGGGGTCAGAGTTCCCACCTGTTTAGCAAACATTGAGATACGAGCTGCGGTAAACGTCTCTTGG GAATGTGACTGGTATGTAAAGCAGAAGATTGGGGGTACAGGATCGGGGTAGTAGATTATAAAGATCTGGGGTCCCTTCTGAGGACCCAGGAGCTGCC CCAGGAGAGTGAATAGAAATGAGCATGCACCAAGTTTATGGACTGGTTTTGCAGGCAGGGGCCTCAGCAAAGGCCCGGAGGCAGGGAGTTGCAAATA GAGAAGCCCTGCATAGCTAGGAGGAAGGCTGGGATTGGAGGGAATCCTGCAGATGACGGGTACTCCAGAGCCTAGAGAGACCAGCTCTCTGCTTACA GAGCTGTGGCCGAGGCTTGTGCCCTGGGGAAGGTTAGGCAAGGCACAGGTGACTTGGGCCCTTGGGGCCTGAAAGGAGCTAGAGGGTGTGTTTTGCG AGCCTGGACAGGTACCCTTTTCTGAGGGTGCCATGATTGTGCATGATTCACACTGATGCGGCAGGAGGGGGCGGGAATTGAAGGGGTGAGAATCTGA CGGGAACTTGGGGTCACACACAGTCAGACCTCTTCTGCCCTCCTATGTCTGGGTCCAAGTCTCATTCCCGAGTCAGCCAACTCCTCCCCCGGCTTTT TGAGGGTGAGCTGTTGGGTGGGTGTGCCGGGGAGGCCATTTTGGGCAGGCTTGCGTGGCAGGGAGGCGGGGCTGGGCTTCGGGGAAACACGTGTTGA ACTGCTAGCCAGGAGTAGGGAGAGGGAAGGCTCAATCTGGTCTGGGGTTGTGAATCTTCCATGCAGATTTGCTGCTTCCGGCTTCCTGGCCTCAGTT TCCCCATCTGAAAGCACAGAGGTACATTGAGCCAGGATCTTCCTGGGAGGTGGAGATCCTATGAGAGTAGGATGGGGGGTAGTGGGTAGGGTCTTTT CCTCCTTGCTTCTCATGACCCTCCCAAGCCCCTGCTGGCTCAAGGAGACCCCGTGCTATGTCTCCCCACACTGCCCACCCTGGCTTACTTGTTGGGT TCTAATGCTTTCAAAGAATTTTGTCCCCATCATTTCTAGGGCGGCTGGCTAAGAATGAGTGACAGGTGAGGCTGGGCTTTGTAGGGTATCCTTTTGA CGGCTTCCCTCTTGGGTCGAGGAATGGCTTAGTTTTGAGCACTGTACGACTTTGGGCGGTGAAGTCCTGGAGGGTTCTAAACTAACCCGCCTTCTGG GTTGTGAGGATTGCTTATTTCGAACAACAACGCTAGGGAGTCTGGCAAACAGCTAAGCCCAGGAAGGGGGTTGCGGGTTAGAGGACCCTCTGAGTCA CCGCAGAGACGCCTAGGAAGCTGGAAGACAGCCACGCCCCCTCCGTGGGCTCCTAGGAGCCAGTGACTCAGGTTTTCTGTGCTGCTGCTGCTGAAAA AAAAAAAAATCCCACAGAAAACCTGTTACCATAGCAACGCAGCTCCAATATGATTCCAAGGCCAAGTGGGGCCTTTCCCCCTGGCTGAGCCTTAGAG GGCCCATTCTGGAAGGGGGCTAACTTCCCTTTCCGGCTGAGGTGGGAGGGCCCACCATCTCCTTGGCAACAGGCCCTCACGTCCTTTCACGGTCCCA ACAGAATTGAGAGGCGATTCTTTTTGGCAAGGGAGGGAAACTGAGGCAGAGAGCGGAGAAGACATTCCCCGAAGGGTGCCTGGAGTCCACCTTTGGT GCCTTGGTGGCCTCTTTATTAAAAAGTGGTTGCACAGGCCCCTTTGTTCCAGTACCTGGAGATGAGACCCACATGGTGAGGCCCTTTTTGTTCTCTG TCTGGACGTCTCATTTTTCAGAGGTACTGGGAGGTTGAAGGTTGGTGTATGTCCACAGCACTGTGCTGTCTTGAACTCAGTGCGCATGACATCTTGG GCCAGGGCCTCTCCTTTGTGTGAGGGAAGCTAGCATGCTGGGAAACTCCGACTCCTTTAGTCCACCCACTTTAGTTGTAGTTTTTGTCTTGTAGCCC ATCTGGCTTCCAACTCTCCATCCTCCTGCCTCAGTCTCCAGGGTGCGGCGATGACAGGCATAGGTCACCACAGGCTTCTGGCCTCCACTTGATGGTT GCCGGAGTGGCTGGGAGTGGCTTTTCTTTTCTTTTCTTTTCTTTTCTTTACTTTCAGGCAGGGTTTATCTGTGTAGTCCGGCTGTTCTGGAACTATG TNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGAGAGAGAGATTGGGACTGACTGGTCCCAGTTCTGGCTT TCCCTGACTGTTCCATTCCCCGCAGTGGGCACGGTTAGATCAGGTGGGGTCACTTAGGCTCGCTAGCATTGGGTGTGGCTCTTTTCTGCCCAGTATG CTGTGCTAACTCAGCTGTCCCTGCACGTGGCAGGTCAATTACAGGTAGGCTGAGGGGACAGTGGGTGACACCCTGTATATGTGTAGCCAATTGTTCT CTTAATATTTAGCCATCCCTAGTGTGGGCCAGGGGCAGGAGAGCCATTTCTGCCTGAGAAGGTTGAACAGACTACAGCCCAGAGCTGTGGCCTTGGG GTGGCTGTCTAGCCTGGGATGGCCCTCCTACTCTCCTCTGTGCTTCAGTGGTAGATCCTGTGGAGGCACTGGGCCAGGGTCCTTGGGGACCCATCAT GGAAGCCATGTCTGCTGATCCATATGTCTAGAAGGGGAGGCATCTGTCCATCCCCACTCCTGAAGTCAAGGGACCCCTTGGTCTTGCAGGGTGACCT TGGGCCAAGGCCAGCCACCTCTGAGCTCCATCTTCTGCTTTGTGAGGTAGAGGTAAGAGCCTTTGGCATTGACAACACAGATAGAGACTCGGTTGGG TCAGGGTGGCATTGGCTGGCATACTCTTGGGTGTAGTGTCAACTAAGGATGAGTTCCTAGGGGCAAGGCTGAAGGTGGCATCTACCATCCCATACCA CGTTCTGCTGCCTAAGGACGCCTGAAGACAACTGTGAGACTGGCAGTGTACACTGCTTCCAAGCTGAGGACATTGTTAGAATCCCAGATCCTTGAAA CAATGAGTTTATCTTGTTAGGACCCAAGATCCCACTCCTAGGTGGAGTCAAAGCCTTGGGAGCGGCACCTTATTGGGGCTCAGTGAGGTCATGTGAC ATGGAAACCATGTAGTGTTACTATGTAGCAAGAAGTTAGAAAGCCATGCAACAAACCTGTAATTCCAACTCCTGAGGCAGAGGCAGGTGGATCTCTG ATTTCAAAGGTAGCTCCAGATACACTGTGAGACCTTCTCAAAACAAGACAAGCAGACTGGAGAGATAGCTCAGAGGTTAAGAGCACTGGCTACTCTT CTAGAGGTCCTGAGTTCAATTCCCAGCAACCAGTTGGTGGTCACAACCATCTGTAATGGGATTCGATACCCTCTTCTGGGGTGTCTGAGGAGAATGA CAGTGTAGTCACATACGTAAAATAAATAAATCTTTAAAAAAAGAAAAGAAAAATGAAAAGGGAGGGGGGTGATGGAGACATGGCTCAGACAGTTTTT TGTTTGTTTTGGCTTTTTGGTGTCTTTTCTTCTTTCTTTCTTTCTTTCTTTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT CTCTCTTTCTCTATCTTTTCTCTTCTTGTCTTGTCTTGTATCTGTGTAGCAGCCCTGGCTACCCTGGAACTCACCTATAGGTCAGGCTAGCCTTGAA CTCAGAGATCAGCCTGCCTTTGCCTTCCAATGCTGGGTTAAAGGTGTGCTCCAGCACTGTCCACTCTGGACCACTTGTTCTTGTATTCACCTAGTTC TCACAGGGTGGCTCATGACAGTTCCAGGCGACCTGACCTCTTAGGGCACCAGGCACATGTGCGCATATTCATACACACAGGCAAGACGTTCACACAC GATACATACAATACAAGACGTATCTTTCTAAAAATTAAAGAAAATAAATGAGAAGCGAGAGGGAAAGGAGGGAGAGCCACTGTTTGGACTGGACCAC CACTGGCAGGGAAATGCCAGAAGGTTCAGACAGCATTCAGGGTTTGTGGCTGGTGGGGGCAGGGATAAAGGAGGAGTTTTCTAAAGGAACATGTGGT CTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTACTAGGGGTAGACTCCAGGGCCTTCCACCATGCTGGGCAAACAATTTA CACTGAGCTATATTTTCGACCCCCTCTTTATTTTATTTTTATTTTATTTTATATATAGCTCTGACTGGCCTAGAACTCATTATGTAAACTAAGGTGA CCTCAAACTCACCCATACTCAAATGAGATTCACCTGCCTCTGCCTCCTGAGTGCTAGAGACAGTCATGAAGCACCACGCCCACCTTCTCTTTAAAAA AAAAAAAAAGCCTATTGCTTTTGTTTTTATTTTTGTCTGTGGAGGGTGGTGCCCACACCCAGTGGTGCCAGTTTGGAATCAGTTCTCCTGCCCTATT CTACCTAGGGATCGAACGCAGGTGGGTAGGTTTGGCAGCAGCTGCTTTTACCCCACGAGCCATCTCGCTGGCCTGTAGCCCTTTGTGTGTCTGTCTG TCTGTCTGTCTGTCTGCATGGAGTGGAGTCTCATGTAGCTCAGGCTGGCCTGCGAGTTATGATCTTCCTGACCCTGGTATCCAAGTGCGGAGACTGC AGGCTCACTCTGCCACGCCCTTTTACACAGTTCTGGGATGGACTCTGCATGTCAAGTGAGTTATAGCCACGGCCCTATTTTATTTTATTATTTTTGA GATCGGGCCCCACTCATCATGGAGGCTAAGGTCGGCCTCCTGAGTGGTGGGATGACAGGCGTGGGTCGATGTGCCTGGCTCCTACTCTATTCTTTTA CTTTCACACATACCCACTACAGGAAGCGAGTAGCGAGCCCCCTTTTACCAGCACCCCGCCATGTGACATTCCGCAGAACCAGCGCCATCTGTGTGTT TATTCAATGGTTTTGGTTGTATTTAAAGCAAATTCCCCACACTGGTGCTTCTTACCCGGAAACGCCTCCATCTGTAGCTACAAAACCAGGCCATTCC TTACATAACGGCAGCGTTGCCTAACTGGAACCGATCTTTAAGACCCAATCCAGGCCCACGGGAGAGTTCTGCTAGGCCTTAGAACATCTTTGTGGGT GGTTCGTTTGAAGTTTGATGGCTTCCTTCCTCCCCTGCTCCCCTTTCTCCTTGCCATTTTGGGCACTAGAGTTTAAAGAAACCCGCCTGCCACTGAA CTAAATCCCCAGATTTTTTTTTTTTTAAGTTTTTTTTCGAGACAGGGTTTCTCTGTGTAGCCCTGGCTGTCCTGGAACTCACTCTGTAGACCAGGCT GGCCTCGAACTCAGAAATCCACCTGCCTCTGCCTCCCGAGTGCTGGGATTAATGTCTTATGTATCCCAGACTGGTCTTGAACTTGTGGTCATGCCTG GAGTATCCTATTTTGATTGTTTATGTGTATACCCCTAATATGGATGTCAGAGATTCATATCATATGTGCCGTCTTTGGTCATCCTCCATACTTTTGG GGGATGTATGGGGGCAGGGATGGAGTCTAGCCTGGGCTGTGGTAACACACGCTTTTCATTCCAGCATTAAAGCAGAGATAGGTCGATCTCTGAGTTC TAGGACAGCCTGGGCTACACAGGGAAATTCTGTCTCAAAAAAAAAAAAAAACAAAAAGAAAGAAAGAAAGGAAAAGAAATAAGAGTCTCCCTATATA GCCCTGGCTGTCCTAGAACTTATTATGTAGACCACGCTGGTCTTGGACTCACAACAGAGATCCATCTGCCTCTGCCTCCTGAATGTCCACTCTCTGC TTGGAGACAAGAATCGCTCAGTGGCCCGGATTCAGGGATTCAGCTAAGCTGGCTGGTCCCTGAGCTCCAGGCCTCCATCTGTCTTGGCTTCCCTGTG ACAGGATTATCGGCTCATGCCACCGCGCCTGGCTCTTACACCATTCCTAGCGATCTGAATTTAATACTCTATGGTCAAGCCATCCTTCAATGCTCCC TCCCCTCCTGTTGAGACAGAGTCTTACTCACTCGGTAGCCTGGGGTCCCAGAACTCACAGTTAGTCTCCCGTTTGTTTCCTGAGTGGTGAGATCGTT CCTGGCTAGCCTTGGCTGCTGATTTGGTAGCCTGGTCCCGCCCACTGCTTAGGATTATCACTGAGGAGTTTAAGCCACACTTCAGGAAGCCCTGTGG ATCCTGGAATCTGAGTGAGACAAGGGTCACACAGTGGCCTGACCGGCTCTGGTCTCTCTCTGCAGGAATGGACCTGTCAGCCAATCAGGATGAAGAG ACCGATCAGGAGACCTTCCAGCTGGAGATCGACCGCGACACAAGAAAGTGTGCCTTTCGCACCCACACGGGCAAGTACTGGACACTGACGGCGACCG GAGGTGTGCAATCCACTGCGTCCACCAAGTGAGTGACACCCTACACCCCTTCATCACCTGGCCTGGCTCTTCCCCCAGGACTGGGCAGCCTGCTCGA TGCCCCCACGTTGCCAGCCCCTCTTCTCTTCCCCAGGAACGCCAGCTGCTACTTTGACATCGAGTGGTGTGACCGCCGGATCACTCTGAGAGCCTCC AACGGCAAGTTTGTGACCGCCAAGAAAAATGGCCAGCTGGCCGCCTCGGTGGAGACAGCAGGTAGTCACTTGGGGGCACGTACCCTAAGCCTGTTTC CCTAGTACCCCGTGGTCAACCATCAGTCCCACCTGGACCTCTCTGTGTGTTCAGGGAATCCCTGTAAGCTGGTGTACCCTCAGGCCAGCAGCCTGTG ACCCTTAGCTTCTTGGTATCCCTCTCTGCTGAGCCATTCCCTGACTGGCCCATCTTTGTTGCTGTGAAGCTCACTGGCTCCCTTTCCCTGTGGCAGG GGACTCGGAACTCTTCCTCATGAAGCTGATTAACCGCCCCATCATCGTGTTCCGGGGGGAACACGGGTTCATTGGCTGCCGCAAGGTCACGGGCACT CTGGATGCCAACCGTTCCAGTTACGATGTCTTCCAGTTGGAATTCAATGACGGCGCCTACAACATCAAAGGTGGGTTCACTGGGTGAGGATGCACCT GGCCATTCAAAGCCGACATTAGGGAACGGGTGTCCTATGACCGCCTGGGGTAGCCCCTCCCCCCTTGTCTTAGAACTTTCCTGGCCCAACCTGGGCA GACAGCGAAGGTGGGAAGCAGCTAGGGAGAGTGGTCGTGGCTCCAATCTGGGAATCGGAGACAGGAGAATTATCTTTTTTTTTTTTTTGGTGTTGAG GACAGAACCCAGGGCTTTGAGCTTATTAGGCAAGCATTCTACTGCTGAGTTAAATCCCCAACCCCAAGAATCATCTCAAAAAGAAAGAAAGAAAAGG GAAAAAGAAGGTGGAGCCTGGTGGTGGTGGTGGCGGCGGCGGCGGCACACGCCTTTAGTCCCAGCACTCAAGAGGCAGAGGCAGGTGGGTCTCTGAG TTCTTGCCAGCCTGCTCTACAGAATACATTCTAAGACAGCCAGAGCTATGCAGAGAAACCCTGTCTCAAAAACAAACAAAAAAAGGGGGTGGGGAGA GAAGATAGAAGATAAGGATATTCCTTCTTAGCTAGCTGTGGGACCAAAACCAGTGAGAGGACACAGCAATCCAGAGGTGTCAGTCAGAATCAGAGCC CTGTGCTGTGTGTGGCCTTAGCAAGGCAAACGGGACTCCTTTCTTACAGTGCTGAGGACTGGACTCAGAGCTAAGATCCAGCCCCTCCCTGGGGGAT TCTAGGCAGGGGCTCTACCACTGAGCCACGCCCCCAGCCCCTCACTGGGGGATTCTAGGCAGGTGTTCTACCACTGAGCCACGCCCCCAGCCCCTCA CTGGGGGATTCTAGGCAGGGGCTCTACCACTGAGCCACACCCCCAGCCCCTCACTGGGGGATTCTAGGCAGGGGCTCTGCTGCTGATATATGTCCTT TTTGTTTGTTTACTTGTTTGTTTGTTTGTCTTATTGTGGCCCTAGCTGTCCTAGAACTTGCTTTGTAGACCAGAGATATACCTGTCTCTGCCTCCCA AATGTTGGATTTAAAGGCATGTGCCACCATGCCCCACCCTAGCCTAGCCCTCTTATGTTTTGTAGTTTGAGATGGCATGTCAGTAGATTTCCCAGGA TGGCCTTGAATCTAGGTAATCCTCCTGCCTCAGTTTCTTGAGTATTTGAATTATGGGACTGTACCTTACATCCAGCTGAGCCCACTCAGTTCTGGAA GCTGACAGCGGGAGGGAGTGTTAATCCTTTGGGGACTGACAAGGTGGGGTTAACATGTAGTCTCCCTCCTCAGACTCCACGGGCAAGTACTGGACGG TGGGTAGTGATTCCTCGGTCACCAGCAGCAGCGACACCCCTGTGGATTTCTTCCTTGAGTTCTGTGACTACAATAAGGTGGCTCTCAAGGTGGGCGG CCGCTACCTGAAGGGGGACCACGCTGGGGTCCTGAAGGCCTGCGCGGAGACTATCGACCCCGCCTCACTCTGGGAGTACTAGGGCCACCTGCCCTCT GCAGGCCGCTCTCGTCAGTCCCTCCTGTTATCCTTACTCATCGGGTGGCCCTGCAGCAGGTGGCAAACCCCTTGCCTTTCAAACTGGAAACCCAAGA GAAAACGGTGCCCTTGCTGTCACCCTCTGTGGACCCCTTTTCCCTAACTCACTGCTCCCCATGGGTCGGTGGCTGCAGACTGTCCCCAGGAGGGACT CTGGTTCCCTCTGTCCCCTTCTTTCCATGGGGAACTCTGGCACCTTTCTTCTGACCTCAGTCAACTGTGAGCCTTATTTCCCCCCAGGAAGTGGCCT AGGAGAAGCTACAGGGCCTAGGGACTTACCCTGAGCTTGTAACTGGAAGACCCCGTCCCTATCCCCGCTCCCGCCCCCACCCCACCCCACCCCTGCT CTGGCCCCAGCCTCTGGAGGCCAGCCTTTTGGCGGGACTGAAGCCGGGCATGGCCAACCTTGCCCACAAGTGTTTTTCTGGATCTTGGCTGGAAGGC AGTCTGTCCCATCCTGCAGTGTTTGGGCCTGGCTCTTTGACTCAAAGCTAGCTAGGTGGCACGCCGTGTCGCTCCTGCACATTCTGGAAGGGGCGGG CCTCTCACCCACCTCATTCCTTTTCCCCCTGGCCTGACTGGAAGCAGAAAAATGACCAAATCAGTATTTTTTTTTTTTTTCTTTAAGGAAATGTTAC TGTTGAAAGGCCCTAGGCAAGCCTGCCCTGTTGGTTGTAGTCGTGAGTGGTCTTGGGGGGAGATGCTTGGCTCCTGTCCCTGCCTCCCCAGCGGGTT CCCTCCCTCCCTCCTGCCTGACCACCCCAGCTCTGGCTCTGTGATTGGTGCTCCACGTCTTCCCAGACACCTCGGGGCTCCTGGGCGGGAGAAAGCC GGATGTGCCCCTCCCTGGGAGCCCTGGAGTAAACCTCAGGGGGCCCTTTCCCAATCACCCCCTTCCACCGACCCCTCAACACCATGCATCTCACTCT GGGTGTCTCGCTCCTTTATTTTTTTGTAACTGTCATTTCTATAACTCTGAAGACCCATGATAGTAAGCTTTGAACTGGAAAATAAAGTAAAATCAAG TCTGCGGCCCGTGTGTGTCTCAGGGGAAGTGGATGCTGGAGTGGGCAGAGGGCCGGCTGGGAGGGAGGCAGCGCTGATTGATTGGCAGCCCGCAGAC TCTTGTTTCGGTCTCGGACCCTAGCGGCTTCAGCATATGCCTTAGTAACTCTGGACTGAGAAATGGCTGACACGAGGTTCCCGAGCCTTACAAGCTG GGCAGGCTAGAGGGTTCAGCAGGTAAAGTTGTGTGCTGTCAAGCTTGATCAGACTGAGTCCCCAGCACCGTGTGAAAAGTTGGGCACAACGGTGTAC ACCCACCCCAGGGCCTCTGGCAAGCACAGAGACAAGAGGATCCTTGGAGCCTGCTGGCGGCCCAACCTTGCCCAATCTGTGATTCCCATTGAGTGAG CCATAAGGTGGAGATGGGTTTTGGAAGATACCCCACATAGGCCTGCGGCCCCCCACACCCGGAAATAAAAACAAGCCAGGCTTGTCATCCCAGTTAT TCGGGGAGCTGAGGCAGGAGGATCACAGATTTAAGACTGCCCAGGTTGAAGAGTAAGTTCAAGGGCAGCCTGGACATCTTGCTAGATTGTTTTTTTG TTGGTTGGTTGGTTTTTGTTTTGTTCTTTTTTTCGAGACAGGGTTTCTCTGTGTAGCCCTGGCTGTCCTGGAACTCACTCTGTTGACCAGGCTGGCC TCGAACTCAGAAATCCGCCTGCCTTTGCCTCCCGAGTGCTAGGATTAAAGGTGTGCGCCACCATGCCAGGCTTAGATGTTTTAAATGAAGGGCTGTG GAGTGTGGTTCACGGGTAGCCTCGCTCAGACAGGCTGGGGCAGGAGAAATGGATGGCTCAGCATTGGCTGCTGCCTTAGGGTTTCCATTGCTGTGAA CAGACACCATGACCTGGCAGCTCTTCTGAAGGACATTGGACTGGGGCTGGCTTACAGGTTCATCAAGGCAGGAAGCAAAGCACAGGCATGGTGCAGG AGGGGCTCAAGTCTACGACCCGGGTCTCAAAGCCCACCCCCACAGTGACAGACTTTCTCCAACAAGGCCACACCCACTCCATCAAGGCCACACCTCC TAGTAGTGCCACTCCTTGAGCCAAGCTTATTCAAACCACCAATCACAACTGCTTTTCTAGAGGACCCAGGTTCAATTCCCAGCATCCACATGACAGC TTACAATTGTAACTACAATTCCAGGGGATCCAACACCCTTACACAGGCACACTTACAGGAAAAGCACCAATCAGTGCACATAAAAATACATAAATCG TTAGAGAGAAGAGACCATTAGCTACCTTCACCCTTAACAGGCAAGCTGAGGTCCTGGGAGTGTGTTAGAGGTCCGCAGCTTGGAGTCTATAGGGTAG TGGCATCGTCTATACGTTCCTTCCTTGACAGGTAGGTACTTAGCTGAGACCTCTGGGGTATCCCAGAGACCCATTTTACAGAGGGAGGCACTGAGGC GGAGGGAAAAGACAACCTTGTTTGCTGGCTCAGAAGAGTGCCAGTGGGGTACCCACCCACAAGGCTCAGCATCCCGAGGCACTGTGGAGGCAGTTAC AAAGCCGCATTGATTGGCTGCTGATGACGAAATGAAGAGCCCCGCGGTGTGATTGGCGGTCCCAGAGGGAAGGCATGTGGGGAGATTGACAGGGGCA GATGGCCACAAAGGGTCCAGTGACTTCCCGCAGGGTGGAAGCTCTGGGCCCAAGCCAGTAAAGTGTCAATGACATGGAGAGACAGATGAATCCTTCC CAGTTGAATTCTCAGGCTCTGGTGGGGCCGCGCTGGGGAGAAAAGACACCCTGTCCGTTACAACCACCAAGCGCAGCCAGGCTACGTGATGACTGGG GGAAGTCCCAGACGTGACTTCCTGCAGCACTGGAGGGGAGGGTCCGACGGAGGAGGCTGAGAGTCTGTTGGAGGCAGCCGAGGATCGGAGGGAAGAG GCACAGGTCTTACATGGGAGGCATAAAGTCTGGTGGGAGTCCAAGGGAGGACGGATGTAGGGTGATGGGAAGAAAGGACCTAATCCAGAAAAAGGAA CAGAAGAGCCACCTACCTGGTTAGGGGACGCTGGCCCTCCGCAGGGAAAGCTGTCAAAGAAAGGCCTGGCTAATGAGACCATGTCGTGGGGGGCCCA GGCAACTGTGGAGGCATCAGACACCTTGGGGCAAGGAGGGCACCCATGAGCTAGTACACACCACTAAGTATCTCAGAGTCCTGCACACACACTCATT GACACAGGTGGGTGAGCAGCACCCACGGGCAGCTGAAGCTGAGTATCCTGCCCGCCCCTTTGTTTCTTCCAACTGAGCAGGGACAAGAAGGATCCCT ATGAATATGGCTTTTTTTGTTTGTTTGTTTGGTTGGTTGGGTTTTTGACTTGGTTTGGTTTTTCCAGACAGGGAGTAAAGACATACACCACCATAAC CCAGCTTTGTAAATCTGGTTTTTGTGTGTGAACCTATGAATTCCACTCCTGTTGCACTGATGGGAAATTGAGGCAAAGTCTCAAAGAAGCTGACAGC ACAGGCTAGTGTGTTCATTTTCTCTCTACAAAAAGAGGAAAAATTGGGGCTGGTGAGATGGCTCAGCGGTTAAGAGCATTGACTGCTCTTCCAAAGC AGGTCCCGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCTATAATGAGATCTGAGACCCTCTTCTGGGGTATCTGAAGACAGCTACAG TGTACTTAGATATAATAAATAAATAAATCTTTAAAAAAAGGAAAAATTATTTATTATTTTATTATTAAATTAATTGTTGTATTTATTTATTTTATTA ATCTATATTTAATTTATTTTTTTATTTTGTGTGCATGAGTGTTTTGCCTGCATGTGTGTGCACTACCTGTGTGTCCACTGCCTATGGAGGTCAGAAG AAGGCGTTGGGTCCGGGAACTGGGGTTGTATGGTTGTTAGCCGCCGCGTTCATGCTGGTTCTCTGCGAGGCGGCACTTAGTCCTGAGCCATCTTCTG TCAGCTCCTCTACTTTCTTTTAGACAGGGTCTCCTGTAGCTCAGGCTGGGCTTCAGCTTGCCTGGTGGTTAAGGGTGACTAAGTTAAATCATCTTAC ATTTCTGCCTCACTTCCACCTCCTGAGTGCTGGGCTTGCAGGCATGTGCCACTGGGATGGGTTTTGTTTCCTGCTGGCTTCTCACCCCGTAGCTCCG TGTGTTGGGTCAGGGCCAGCCCTGTGCCCACTGAGCCATTAACCCTACTGAGCCCACTGTAGGGAAAAACCATAGAGGAGCTTCTATGACCCTCATG GGTCCCTCCAGGTCTGTCAGAGTTCAGGAGGCATGGATCTCTCTGGCAGGGAGCTGTTGACTTTAGCCTTGGAATTTCCCAACCAAGTCTACACTGA GCACCCTGTCGACGACCTGCTTCTGACTCCTCCTGTGAGGCTCTTTTGGAGTGATCTTAGTCCCCACAGGGCCCCCATCTTCTCCAGAGCTGAGTGG CCTCTCCTACTGGACAGAGAAGAGCTGTCCTGACTTGGTTAAAATGTTGAATGCAAGGAGCGGAGGAAACGGCCCAGCTGGTGAAGTGTTTGGCTCG ATCCCCAGAGCTGTGGAGTTCCCAACAGGATGGGGCTCACTGGCTGCCCTGATCAGCAAGCTCAGAAACCAAGATGGATAGCTCCTAAGGACTGGAA TTGGAGGATGACCCCTGGTGACAGACACACTTGCATATGCATCTGTCTGCACACATACACATATGCATGTAAAACCCTGATCCACGTGGTAGTGCCT GACTGTAATCCCAGTACTTGGGAGACAGGAACAGAGAATCACCTTCAGTTTGAGGCCAACCTCGTCTACATATCCAGCACCTTAGGAGACTCTGTTT CCAACTCTTCAGGGTGGCTCACATCTCTAATCTCAACCCTCAAGAAGCCAAGACTGGAAGATGCCTAGAGAGGAAGGTTTGCTTGGGTTCAGTGCCA GCCTCCAGAGGCAGAGGCAAGCAGATTTCTGAGTTCGAGGCCAGCCTCTACAGAGTGAGTTCCAGGACAGCCAGGCAGCCAGGGCTATACAGAGCAA CCCTGTCTCAAACAACAACAATAACAACAACAACACAACAAGAAAACTTGAGTGTGCGTGTGCGTGTGCGTGTGCGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTTTACTATTTACAGTAAACGAGTCTTTGGGGAGGCAGCCAAAGTAGGCGAGGAACTCCTTGTCCCCTGCTGGGCTCTCTGGGTTGAGATC TTGTCTTGATGGGGAGATAGGAAGGGATTCTCTGTCCCTCAGGGTGCTATCAGCAGTGGGAACAGATGGGGTCGGGAGAGAGACTGGGGGAGGGGAG AATCAGGGTGGAGGAGGGCTGTGATTTAGGTTTACCATGAAACCGGAGTCATCACCGGTGGGAGAGGCTGGTCAGAGTTCCTCTTTTTTCCTCTTCT TTCCCTAGGACCCAGGCCTGATCCGGTGGGGAGGGGAATGATTGGAAAATGCTGCCTTCTAGAGTCCCTAGCGAGAGCCACACCCCAGGCCTCAGCC ATCAATGACAACCTTTCTGTTCTCACTGAAAGCAATTAAAGATCTGTAAGATGAGTCAGTGTTACCCATTGTAAGCTGCTGACTGCCTTGGTCCCAT CCCTGGGACCCACATGGTGGAAGGAAAGAATGGACTGATGCCCTTGGACCCCCACGTGTGTGCTGTGGCACACACACACACGCATGCACACAAAAAT AAGTAATGTAGTTCAAAATTTAGAATAAATCAGGCGTGGTGGTGCACACCTTTAATCCCAGTACTCGGGAGGCAGAAGCAAGTAGATCTCTGTGAGT TTGAGACCAGCCTGGTCTACAGAGTGAGTTTCAAGCCAGCCATAGATAGCTACATAGCCAGATCTTGTGTTAGCCTCCTCCTTCTACCAACAGAAAT TAAGATCACAAATAAACAGGAAAGAGGGTGGAAGAGACAACTCAGTGGCTATGAACATTTGCTGTTCTTGCAGAGAAACCAGGATTGAGTCCCGGCA CCCACATAGTGGGTAAACATTATCTCTAGCTCAAATTCCAGAGGACCTGGCTTCTGAGAGCACGGTACACATGGGGTGTTCTCTCTCTCTCTCTCTC TCTCACACACACACACACACACACACACACACACACACACACACGCAGGAAAAACAGAAAAGCACATAAAATAAAAACAAATATATAAAAATAGAAT CCAAGGGGATTCAACGATGTCATGAGTCCACAGAAATCCTATCCTCCCCTTTTTCGGGGTGTTACACGGGCGGATCAAACCCAGGGNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGACTGCTCTTCCAAGGTCTTGAGTTCAATCCCAGCAACCACATGGTGGCTCAC AACCATCCGTAATGAGATCTGACGCCCTCTTCTGGTGTGTCCGAAGACAGCTACAGTGTACTTACATATAATAAATAAATAAATCTTAAAAAAAAAA GAAAGAAAGAAAGAAAGAAAGAGAGAGAGAAAGAAAGAAAGAGGTGAGGGCTGGGTGTGGTGGCGCACACCTTTAATCCCAGCACTTGGGAGGCAGA GGCAGGTGGATCTCTGTGAGTCTGAGGCCAGCTTGGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTACACAGAGAAACCCTGTCTTGAAAGAAAG AAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGGAAGGAAGGAAGGAAGGAAGAGGTGAATAGGAT AAAATGAGGTCCAATAGGTTGGGGGCATGGCTCAGTGTTAGAGGGCTTGCCTAGCAAGTGAGAGGCCTGGGTTCAACCTCTGGCACTGAAGAGGGAT GGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTATCTAGATAGATAGATGATAAATAGGTAGATGGATGGTAGATATATAGATAATAGATGTGGGATAG ATAGATGATAGAGATATACATAGATGATAGATTATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGACAGACAAATGGTAGG TATATAGATGATAGAAAGATGAGGGATAAATAGATGGTAGATAAGTAGATGATAGTAGGTAGATGAGAGGGAGAGAGAGAGAGAGCGAGAGAGAGCG AGAAAGGATATAATAAGGTCATTAGGCTAATTTGATCCAAAGACAGATTGGGGTTCTTATAAGACAAGTGATCAAGCAGGCCAGATATGGGGGGAAC TGATCTGTAATTCTAGCACCTGGGGTGGGAGATGGAGGCAGGAGGAAGGGGAGGTCGAGGGTATCCGCAGATACTTAGTGAGTTTGAGGCTATCCCC AGCCACGTGAGACTCTGGCAAATCCTTCCGCACTAACAACAAAAATTCTGAAAGGCAAACCTCCCTTAACTCATAAAGCATGAATTGGGGCGTATGC GGGCCTTCAGAGCCATGTGGTGTGTTTGGGAACAGACGACAGGAAACACTGTTGAGAGGACTCAGACCCAGAGAGGAAGGGACAGCAGAGTCACCAT GTGGACAGGCGTTGGGGCTTGCTGGGCCGCTCACAGGAAGCAGCGCACACCAGAGCCATCCGCCTAGGAGCTGGGCCACAGTTTCCTGCAGAGTGGG CCCTGACACACCCGGCCAAAGCAAGCACTGGCCTGTGGACAGAAAGCAGACACAGGACGGAGCCCGTTCCGGGGTCAGCTCACTGTACTTGAAGATG TGAGCCCAAAGAAGTGGGGGGTGCCACGGCGTCTTTTGCAGATGTTACTATGCCAGTTGGTGTTAGACACTTAGATATATTTTTAAGAAGAGCAGTC GGTACTCTTAACTACTGAACCATGTCTCCAGCCCCACAATGACATTCTTCAAAGAGCAGAGCTTAGAGGCACAGGCACTTGTCACCAAGCAGCAACA TGAGTCAGATCCCTGAAAATCCACAGGCAGAAGGAGAGAGCTGACTCCTGTCCGTTGACCTTCATGTGAATACAGTGGTGTGTGGTGGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGCATTTATGCCATGTGTGTCAAGAGTGTGAGGAGGACCCAAGAGAGTTCCTAGACTTAAAGCTGGTTNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN MOUSE SEQUENCE - mRNA GAGCTAAGCCGTGTTGAACAAAGGAGGTCGGGCACAGCTATCCAAGCTCCCGGGGCCACCGGGCCGCCCTCCGCCACCATGACCGCCAACGGCACGG CAGAGGCTGTGCAGATTCAGTTCGGGCTCATCAGCTGCGGCAACAAGTACCTGACAGCCGAGGCGTTCGGGTTCAAGGTGAACGCATCCGCTAGTAG CTTGAAAAAGAAGCAGATCTGGACGCTGGAGCAACCTCCCGATGAGGCGGGCAGCGCGGCCGTGTGTCTGCGCACGCACCTGGGTCGCTACCTGGCC GCCGACAAGGACGGCAACGTGACCTGCGAGCGCGAGGTGCCCGACGGCGACTGCCGCTTTCTCGTCGTGGCGCACGACGACGGCCGCTGGTCGCTGC AGTCCGAGGCTCACCGGCGCTACTTTGGCGGCACCGAGGACCGCCTGTCCTGCTTCGCGCAGAGCGTGTCGCCGGCCGAGAAGTGGAGCGTGCACAT CGCCATGCACCCGCAGGTTAACATCTACAGCGTTACCCGCAAGCGCTACGCGCATCTGAGCGCGCGGCCGGCCGACGAGATCGCGGTAGACCGCGAC GTGCCTTGGGGCGTCGACTCGCTCATCACCTTGGCCTTCCAGGACCAACGCTACAGTGTGCAGACGTCCGACCACCGCTTCCTGCGCCACGACGGGC GCCTTGTGGCACGGCCGGAGCCCGCCACGGGCTTCACGCTGGAGTTCCGCTCCGGCAAGGTGGCCTTTCGCGACTGCGAAGGTCGCTACCTGGCTCC GTCCGGGCCCAGCGGCACCCTCAAGGCTGGCAAGGCCACCAAGGTGGGCAAAGATGAGCTCTTCGCCCTGGAACAGAGCTGCGCTGAGGTGGTGCTG CAGGCGGCCAACGAGGGGAACGTGTCCACGCGCCAGGGAATGGACCTGTCAGCCAATCAGGATGAAGAGACCGATCAGGAGACCTTCCAGCTGGAGA TCGACCGCGACACAAGAAAGTGTGCCTTTCGCACCCACACGGGCAAGTACTGGACACTGACGGCGACCGGAGGTGTGCAATCCACTGCGTCCACCAA GAACGCCAGCTGCTACTTTGACATCGAGTGGTGTGACCGCCGGATCACTCTGAGAGCCTCCAACGGCAAGTTTGTGACCGCCAAGAAAAATGGCCAC GTGGCCGCCTCGGVGGAGACAGCAGGGGACTCGGAACTCTTCCTCATGAAGCTGATTAACCGCCCCATCATTGCGTTCCGGGGGGAACACGGGTTCA TTGCGTGCCGCAAGGTCACGGGCACTCTGGATGCCAACCGTTCCAGTTACGATGTCTTCCAGTTGGAATTCAATGACGGCGCCTACAACATCAAAGA CTCCACGGGCAAGTACTGGACGGTGGGTAGTGATTCCTCGGTCACCAGCAGCAGCGACACCCCTGTGGATTTCTTCCTTGAGTTCTGTGACTACAAT AAGGTGGCTCTCAAGGTGGGCGGCCGCTACCTGAAGGGGGACCACGCTGGGGTCCTGAAGGCCTGCGCGGAGACTATCGACCCCGCCTCACTCTGGG AGTACTAGGGCCACCTGCCTCTGCAGCCGCTCTCGTCAGTCCTCCTGTTATCCTTACTCATCGGGTGGCCTGCAGGAGGTGGCAAACCCCTTGCCTT TCAAACTGGAAACCCAAGAGAAAACGGTGCCCTTGCTGTCACCCTCTGTGGACCCCTTTTCCCTAACTCACTGCTCCCCATGGGTCGGTGGCTGCAG ACTGTCCCCAGGAGGACTCTGGTTCCCTCTGTCCCCTTCTTTCCATGGGGAACTCTGGCACCTTTCTTCTGACCTCAGTCAACTCTGAGCCTTATTT CCCCCCAGGAAGTGGCCTAGGAGAAGCTACAGGGCCTAGGGACTTACCCTGAGCTTGTAACTGGAAGACCCCGTCCCTATCCCCGCTCCCGCCCCCA CCCCACCCCACCCCTGCTCTGGCCCCAGCCTCTGGAGGCCAGCCTTTTGGCGGGACTGAAGCCGGGCATGGCCAACCTTGCCCACAAGTGTTTTTCT GGATCTTGGCTGGAAGGCAGTCTGTCCCATCCTGCAGTGTTTGGGCCTGGCTCTTTGACTCAAAGCTAGCTAGGTGGCACTCCGTGTCGCTCCTGCA CATTCTGGAAGGGGCGGGCCTCTCACCCACCTCATTCCTTTTCCCCCTGGCCTGACTGGAAGCAGAAAAATGACCAAATCAGTATTTTTTTTTTTTC TTTAAGGAAATGTTACTGTTGAAAGGCCCTAGGCAAGCCTGCCCTGTTGGTTGTAGTCGTGAGTGGTCTTGGGGGGAGATGCTTGGCTCCTGTCCCT GCCTCCCCAGCGGTTCCCTCCCTCCCTCCTGCCTGACCACCCCAGCTCTGGCTCTGTGATTGGTGCTCCACGTCTCCAGACACCTCGGGGCTCCTGG GCGGAGAAAGCCGATGTGCCCCTCCCTGGGAGCCCTGAGTAAACCTCAGGGGGCCCTTTCCCAATCACCCCTCCACCGACCCCTCAACACCATGCAT CTCACTCTGGGTGTACTCGCTCACATTTATTTTTTTGTAACTGTCATTTCTATAACTCTGAAGACCCATGATAGTAAGCTTTGAACTGGAAAATAAA GTAAAATCAAGTCTG MOUSE SEQUENCE - CODING ATGACCGCCAACGGCACGGCAGAGGCTGTGCAGATTCAGTTCGGGCTCATCAGCTGCGGCAACAAGTACCTGACAGCCGAGGCGTTCGGGTTCAAGG TGAACGCATCCGCTAGTAGCTTGAAAAAGAAGCAGATCTGGACGCTGGAGCAACCTCCCGATGAGGCGGGCAGCGCGGCCGTGTGTCTGCGCACGCA CCTGGGTCGCTACCTGGCCGCCGACAAGGACGGCAACGTGACCTGCGAGCGCGAGGTGCCCGACGGCGACTGCCGCTTTCTCGTCGTGGCGCACGAC GACGGCCGCTGGTCGCTGCAGTCCGAGGCTCACCGGCGCTACTTTGGCGGCACCGAGGACCGCCTGTCCTGCTTCGCGCAGAGCGTGTCGCCGGCCG AGAAGTGGAGCGTGCACATCGCCATGCACCCGCAGGTTAACATCTACAGCGTTACCCGCAAGCGCTACGCGCATCTGAGCGCGCGGCCGGCCGACGA GATCGCGGTAGACCGCGACGTGCCTTGGGGCGTCGACTCGCTCATCACCTTGGCCTTCCAGGACCAACGCTACAGTGTGCAGACGTCCGACCACCGC TTCCTGCGCCACGACGGGCGCCTTGTGGCACGGCCGGAGCCCGCCACGGGCTTCACGCTGGAGTTCCGCTCCGGCAAGGTGGCCTTTCGCGACTGCG AAGGTCGCTACCTGGCTCCGTCCGGGCCCAGCGGCACCCTCAAGGCTGGCAAGGCCACCAAGGTGGGCAAAGATGAGCTCTTCGCCCTGGAACAGAG CTGCGCTGAGGTGGTGCTGCAGGCGGCCAACGAGGGGAACGTGTCCACGCGCCAGGGAATGGACCTGTCAGCCAATCAGGATGAAGAGACCGATCAG GAGACCTTCCAGCTGGAGATCGACCGCGACACAAGAAAGTGTGCCTTTCGCACCCACACGGGCAAGTACTGGACACTGACGGCGACCGGAGGTGTGC AATCCACTGCGTCCACCAAGAACGCCAGCTGCTACTTTGACATCGAGTGGTGTGACCGCCGGATCACTCTGAGAGCCTCCAACGGCAAGTTTGTGAC CGCCAAGAAAAATGGCCACGTGGCCGCCTCGGTGGAGACAGCAGGGGACTCGGAACTCTTCCTCATGAAGCTGATTAACCGCCCCATCATTGCGTTC CGGGGGGAACACGGGTTCATTGCGTGCCGCAAGGTCACGGGCACTCTGGATGCCAACCGTTCCAGTTACGATGTCTTCCAGTTGGAATTCAATGACG GCGCCTACAACATCAAAGACTCCACGGGCAAGTACTGGACGGTGGGTAGTGATTCCTCGGTCACCAGCAGCAGCGACACCCCTGTGGATTTCTTCCT TGAGTTCTGTGACTACAATAAGGTGGCTCTCAAGGTGGGCGGCCGCTACCTGAAGGGGGACCACGCTGGGGTCCTGAAGGCCTGCGCGGAGACTATC GACCCCGCCTCACTCTGGGAGTACTAG HUMAN SEQUENCE - GENOMIC TTGCATTTGAAGCTACCATGACTGCAAGAGGGAGTTCCCGAAGGGGTCTGGGAATGGCCCAGGGAAATAGGGGTGAGGTGAGACTCCACTGCCCCGA CAGTGCCCATGTATGAATTAGAAAAAGTGGGCCAGGCGTGGTGGCTCACACCTGTAATCCCAGCATTTTGGGAGGCTGAGTGGGCAGATCATGAGGT CAGGAGTTCGAAACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGCTTGGTGGCACACATCTGTAGTCCCA GCTACTCAGGAGGCTGAGGCAGAAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGGTCATGCCACTGCACTCCAGCCTGGGTGACA GAGTGAGACTTTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGAAAAGAAAGAAAGAAAAAGAAAAAAAGTGGGCCAGGTGTGGTGGCTCATACCTGTA ATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATTGCTTACAGCCAGGAGTTTGAGACCAGGTTGGACAACATGGTGAGACCTTGTCTTTACAAAAA AATACAAAAACCTATCTGGGCATGGTGTTGCATTCCTTTAGTCCCAGCTACTTAGGAGGTTGAGGTGGAAGGATCACTTGAGTTAAGGGAGGAGACC ACCCCTCATATTGTCTTATGCCCAATTTCTGCCTCCAAAGAAAGAAAAAGTAAAAACTAAAAGGCAGAAATGAAAACCACAGGCAGACAGCCCAGCG CCACACCCTGGGCCTCGTAGTTAAAGATCGACCCCTGATCTAATCGGTGATGTTATCTATAGACTACAGACATTGTATAGAAATGCACTGTGAAAAT CCCTATCTGGTTTTGTTCTGATCTAATTACCGGTGCATGCAGCCCCCAGTCACGTACCCCCTGCTTGCTCAATCACGACCCTCTCACGTGCACCCCC TTAGAGTTGTGAGCCCTTAAAAGGGACAGGAATTGCTCACTCGGGGAGCTTGGCTCTTGAGACAGGAGTCTTGCTGATGCCCCTGGCCAAATAAACC CCTTCCTTCTTTAACTCGGTGTCTGAGTTTTGTCTGCGGCTCATCCTGCTACAGAGTCTAGGAGGCAGAGGTTGCAGTAAGCCAAATTCACGCCACT GCACTCCAGCCTGGGTGACAGAGCAAGACCCCACCAAAAAAAGAAAAGAGGCCAGGCGCAGTGGCTCACGCCCAGCTAATTTTTGTACTTTTAGTAG AGACGGGGTTTCACCATGTTGGCCAGGCTGATCTCAAACTCCTGTCCTCAGGTGATCCGCCCACCTTGGCCTCCCAAAGTGCTGCGATAACAGGAGT GGAGGCTCAACTTTTTAAAGAAGAAAAGGACGAATCAGGACAGGAGACAATTACAAGCTCTGTTCATTCGGAATTCTCATTGGCTTACAGAAATAAC TTTGGCTAGTGATTGGTTATATGTTGTAGACAGACCCACAGGGTGGATGGCGTCTGTGGCCACTTGGGCATTAGCTGGTCCAGAGCCCAGAGTCCAT GTAGCAAGTAGCTTCAGGACGTAATTATTTAGCTCAATAGAAAGTGAGATGTGACTGCTGTTACTTTTTTTTTTTTTTGAGACGGAGTTTCACTCTT GTTGCCCAAGCTGGAGTGCAATGGCGCGATCTCGGCTCACTGCAACCTCTGTCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCT GGGATTACAGGCGTGTGCCACCAAGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTATGTTAGCCAGGATGGTCTCGAACTCCTGA CCTTGTCATCCACCGGCCTCGGCCTCTCAAGGTGCTAGGATTACAGGCATGAGCCACCACGCCCGGCCTTTTAACTGCTGTTACTTTTTTTTTTTTA ATCATTTTTATTCTGCTAGTTCCATAAAAGCAATGTAAACACCAGCATTCTATACATCTTGCTGGTGAACTCACATAATGCTTAGTTCCCTGATCCT TTGACCTCCTTGTCTTCTCCAGTTATTTTCTGTTTGGACCACTGGCCACAGGAATGGAGTGGGGTTGGGGCTTAGGAGAGAGCAATGTGGCTTTTTG GTATGACTTGTTTCATTGACTGCTGTTACATTTTAAATGCCTTTCTGGGCCTGATAATTTAAGGGGGCTGGCATTTCTCACATCAAAGGGCAAAGGG TTTTTTTGTTTGTTTCTCACTATTGCTCAAAAGCCACATGTGTCAAGGACAGCTCTTGTTAACGGGCAGAGAAGCTTATAGAACCTTTCCAGGGCTG GCGCGGTTGTTCATGTCTGGGGGACAAGAGCGAAACTCCATCTCAAAAAGAAAAAAAAAAAAAAGAACATTTCCAGGCCAGGCACAGTGGCTCACAC CTGTAAGTCCCAGCACTTTGGGAGATTGAGGTGGGAGGATCACTTGAGGCCAGGAGTTTGAGACCAGCATAGGCCACATGGCAAGAACCCAGTTTCT ACAAAAACATTTTTTTTTTAAATTAGCTGGGCTCGGTGGTGCACACTTGTGGTCCCAGCTACTCGGGAGGCTGAGGTGGGAGAATCGCTTGAGCCTG GGAGGCGGAGGTTGCAGTGAGCTGTGATCGCACCACTGCATTTCAGCCTGGGCAACAGAGGGAGACTCTGTCTCAAAAAAAATCAAATAAAGAAAAA AGAACATTTCCATTATTGCAGAATGTTCTATTGGACGGCGCTGGGCCAGATGCCTGCCCCAAGCCCTGGGACACCCAAACCTGGTGAAAGTGCCAAG CTCCCATCTGGGGGTGCTCACGGAAGGGGCCGGGAGCTGGGATTACAAGCGTGGAGGCAGGCGCCACCCCAGAGGAGGTGGGTGATGTCTGAGCCAG AGTCTTTGGGATGAGCAGGGCTTTGGCAGGCAGCTTTGTTGGGCAGGCAACAGGCACAGCAGGTGCAATGGCATCGAGGTTGGAGAGGTGGACTGGC GGGGAGAAGAGAAGGGAGGGTGGCAGGAGAGATGGGCAGAGGCCCCCCAGGAGCCCAGAGCCTTCAGGGCTTTGGGCCCTCTTGGGGCACTGGGGAG CCACGGGAGAAGTGTGGGGTCGAGAGGGGCGCCCTGGATTTGACCACCTTCAGGAACCTACCTTGGCTGCCCGGGTGGGTGGGATGGAGGTGATGAA GGTGGAGGTCGTAGCATTGTCACTGAGAGCGATGCTTATTCTGATTTTTGCCCCCGTGAGCCTCAGAAATCGGTCAGAACAGTGCTCGGGCTGGGCG TGGTGGCTCACGCCTGGAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCAAA ACCCCGTCTCTACTAAAAACACAAAAATTAGCTGGGTGTAGTGGTGCATGCCTGTAATCCAGCTACTCCAGAGGCTGAGGCCTCCCTGGGAGGCGGA GTGCAGTGAGCCAAGATTGTACCACCGCCCCTCCAGCCTGGGTAACAGAGTGAGACTCTGTCTCAAAACAAACAAAAAAGAACAAACCAAAACCAGT GCTCCAATTCACCTTGCTGAATTGGAGAAGAACAGGTGCCTGGGTCCTCCCGGCTGACGGTGACGTCACTATGAGCCACCACGCCTGGCCCGGTGGG TGTTTACAGCAGAGGTGGTTCAGGGAGGAGTGAGTGGCAGATGGTGCAGGCTCAGGGAGGAGTGAGTGGCAGGTGGGGCCTGAGGCCAGAGGCAGGA GGACCGTTCAAGACTGAGGTGTCTTGGGCACTGGTGCCGGGGCCGGGGAGAGCCCTGGCATGCCGGGCCCCGGCCCTCAGTGAAAGCAGGATGAGGT GGCGGCCAAGCAGGGAGGCCAAGGCCTGGCAGCAGCCGGCAGCCCCTCTCCTGGCAGGGACATCTTGGCAGGAGCCGGGCTCTGCCCAGGGCGCTAA TGTCCTCTTAATTAGCCAGGCACTTGCCAAGCACTTGCCGCTGCGGCCTCACTTTGCAGAACGCACTTGGGTTTGGAGCAGGACCAGCATCGGCCAC CGGGTGAGTAGGGGGGATGGCCAGGTGAGTACCATGGCCAGAAGGTGCGGCCTCTGAGTCCCCACTGAAGCCAATCCAGGCCCCGACCTCTGGTCAT CATCAACAGAAGAGTGACAGAAACAGAAAAGATATCAAGGAACACGTTTTCAGGGCCAGATTCCACGTCCCCCACCTATTTTCCTTTGCTCCTGCCT TGCCTGGCTCTGCCCCCTTGAACTCTTATTCACCCAGTGTAGGCATCACCTCCTCCTGAAGGCCCTCCTGGACTGCACAGTTAACTCTGGAGCCTCC CCTGCACAGGGCAGCTCATGTATGGATCCACAGGTGAGTTCCTGTCTTTGAAGGGTTACAGTTTAGGTCCTGGAGCAGTGGTGGGGAGGTCACACCT CCACCCACATCCCTCTTTGCAAATCCCATGGGAACTATGAGCCTGGGTCCCCCAAACTGCATGTTCCCCACTTAAAGCTGGGCCAGATCCTGTTTGC TGTATCCAGGCCTCAGTTTCCCTGCTTGTAACCAGAAGTCCATGCAGCCAGAAATTGTCAGGGAGCTGGGCACGGTGGCTCATGCCTGTAATCCCAG CACTTTCAGAGGCTGAGGCATGAGGTTCACTTGTGATCAGGAGTTTGGGACCCCAGCCTGGGCAATACAATGAGATCCCTGCCTCTACCAAAAAATT AAAAACAATTACCCAGGCCTGGAGGCATACACTTGTAGTCCTAGCTATTCAAGGGAGGCTGAGGTGGGAGGATCACTTGAGTCCAGGAGTTTGTGGC TGGGGTGAGCTCTGATTGTACCACTGCACTCCAGCCTGGGTAAGAGAATGAGACCTTGTTTTATTTTATTTTATTTTTATTTATTTTGAGATGGAGT CTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGCAATGTCGGTTCACTGCAACCTCTGCTTCCCGGCTTCAAGAGATTCTCCCGCCTCAGCCTCCC AAGTAGCTGGGATTACAGGCGTGTGCCACCACGCCTGGCTAATTTTTTGTGTTTTTAGTAGAGACAGGGTTTCACCATGTTTGCCAGGCTGGACTTG AACTCCTGACCTTAGGTGATCCATGCCCCCTTGGCCTCCTAAATTGCTGGGATTATAGGCATGAGCCACCGGGCCTGGCCGAGACCCTGTTTTAAAA AAATTAATCAGGTCCAGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGAGGGCAGATCACCTGAGATCGGGAGTTCGAGACCA GCCTGACCAACATGCAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCAGGGCGTGGTGGCGCACACCTGTAATCCCAGCTACTTGGGAGGCTGA GGCAGGAGAATCACTTGGACCTGGGAAGCAGAGCTTGTGGTGAGCCGAGATTGCACCATTCCACTCCAGCCTGGGCAAAAAGAGTGAAACTCCATCT CAAATAATAATAATAATAATAATAATAATAATAATAATAATAATTGGTAGAGATGTTGGTAGAGGCAGGACAGTGGGAGTGACAGCCTGGTCCTGTC CTCCCGGGCTCTGGCTGACCATGCTGTAGTGTGGCTCAGGGCCCTGGAGGGCACAGCTGTCCTGTGGCCCTGTGGTCAGCCGGGAAGCCAGGCCTGG CAGGACTCCTGCCCTAGAATCAGCTCCTCCCACTCCCCAGGGTCCCATGCAGGGCGCTGGCCGTACCAGGCCTCCTCGCGGGTGCCACAGAGCCAGC GGCTGCACAGCAACAGAGACGCCATTCACAGGCTCTCGGCCACGAGGCCGCTCATTTACAGAGGGCTGAGCCGCTGACATCTGTGCGTTTGTAACAT GGACAGCATTTCTGGTCCCATACAGACGCCTGGGCCAGCCACATTTATCTCCCCTTGAGAGAAGGGAAACGAGGCTCGGGAGGGAATGAGGGATTGG CTTGGGGTCACACAACTTTAATGATGACCCTGGGCAGGAAGCTCCCAGGATGGCAACAGAGACTCAGGGCAGGCTGGGCATGGTGGCTCACACTTGT CATCCCAGCCCTTTGGGAGGCAGAGGTGCAAGGATCACTCGAGCCCAGGAGCTCAAGGCCAGCCTGGGGAATATAGTGAGAACCCATCTCTAAAAAA AAAAAAAATAGGCCGGTCGCGGTGACTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACGAGGTCAGGAGATTGAGACCATC CTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATAGGCCGGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGA GGCCGGCGGATCACGAGGTCAGGAGTTCGAGATCAGCCTGACAAACATGACGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTG ACACGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCATCGAGGTGGAGGTTGCGGTGAGCCGAGATCGCACTACTG CACTCCAGTCTGGGAGACAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGG GAGGCTGAGGTAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACTAAAGCCTGGGCAACAGAGCGAGAC TCTATCTCAAAAAAAAAAAAAAAAATTTAGCCGGGCATGGTGGTGCATGTCTGTACCCCCAGCAATTTGGGAAGCTGAGGTGGGAGGATTGCTTAAG CCCAGGAGTTTGAGGCGGGAGTGAGCTGTGATGGCACCACTGCACTCCAGCCTGGGTGACAGAGTGAGACCCCGTCTCTCCCTATCCCCCGCAAAAA AAAAAAAACAACTCAGGGCTTTCCCACCCCTGTCCTTGCACAGATGAAGAACCGAAGCTTCTAGAAGGGGTATATTTTGCCCCCAGGCCCCAAATCC TGGTCTTTGGACTACAGTCAAGACCTAGCACAGGGCTCAGGCCTAAAAAAAAGCTGTTGAGGAGGGTGTGAGGCTGCAACGTTGCGGTGAGAAGGGG GTCCCCAGGGAGGGCGCAGCAGGAAGCCCCAGGGAAGTGCCTGGGAGAGGGAGGTTGTGCAGCCAGAAGGAGCAGCCCGCAGCCTTTGGTTGTTGAC TCCTGCTTTGTAAGTGGCAGTCTGGTTGGGTAGGACAGGGTCCGAGTCCTCACTCAGGGAACTGAGTCCAGGGTGAGCTGAGCAGCCCTTCCTGGTG GCCTCACTTTCCCCTGCAGAGCCTGCTGCATGGTGTCCAGTGGCCAGCCTGGGAGGAGCTCAGGACTGGCCTCACCTCGTGCCACGCCCTCGTACCA AGGTGGCTCAGATGGCACCTGGGTTCCCGAAGGGCCCAGGAACACAGCGTCCATGTCCCCATCCTTCCCCGGAGGGACTTGGGGTGGGGCCTGCAGG AAGGATCATGTGACTTGTTCAAGGGCAGCTTGTCCTGCCCCGGACACAGAGGTGCCCATCGTAAGCGAGATGCAGGCAAGGTGAGGACAGGGCATGG TGCCGAGCAGGAATGATTTTCGAAAATGCTACTCTGTGGTCGGGCACGGTGGCTCACTCCTGTAATCCCAGTACTTTGGGAGGCCCAGGCGGGCAGA TCATGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCTTCTCTACTGAAAATACAAAAAACTACCCGGGCGTGGTGGTGGATGCC TGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCTGGAGGTGAAGGTTGCAATGAGCCGAGATTGCACCACTGCACTCCGAC CTGGGCGACAGAGAAAGACTCCGTCTGAAAAACAAACAAACAAAACCCCGAGATTCTCTTTTCCCCCGTCCGGAGCTCTATGGCCATCTGGAGCTCG TTCTGTCCACAAGGACACATTTCCTGGCAGCAGCTGTGGACCAGGGCTCACTCACTCACATCTGTACCCAATCTAGAGCAGGACAAACACCTATCAC CTGCACTGGCAATGGACAGAGGACAGTGGCAGCCCCATCACCAGAGGCATTCAAGCCAAGGCATTTTCTATCGTCTATTTATCTATCTATCTATCTA TCTATCTATCTATCTATCTATCTATCTAGATGAGATCTTGCTATGTTGCCCAGGTTGAACTCCTGGCCTCAAGCGATCCTCCTGCTTCAGCCTCCCA AAGTGTTGGGATTTCAGGTGTGAACCACTGTACCTGGCTGGAGTGCAGTGGCACTGTCATAGCTCACTGCAGCCTCCACCTCCTGGGCTCAAGGAAT CCTCTTTCCTCAGCCTCCTGAGTAGCTGGGACCACAGGCATGCACCATCACACCCAGCTAAACCTTGATTTTTTCCATAGTATATGGCTCAGGGCAG AGCAAAGAAGCACAAAAACATGTTGGCTTGCGGTTGAGGGCTGATGGGAGGGGGTTCTGGCCAAAGCCCAAAATTAACAGCCACAACGTCAGTGTCT GTGGGAGGGGTTGCCAGGGGCGTGCGGGTTCTGGGGCTCAAGGCCCTGCCGGTAAACCCATTTGAAGCAGGATGGCAAGAAGGTGACACCATCTTCC CCCGCGCACTGAAAGCCCCTGGCTGGGATTGCCTGGGGCAGACACAGGCTCGGACCAGCCCCAGCAATCCCAGTTTATCAGCGAGCCGGCTGAGGGC CCGGAGTTATCTCAGTGCCCGGCCTGAGACCTTGTGGGCAGCCTGTGGTCATGCTGGCATTCCAGGGGCCTTTTGGCATGTGGGGAATGTCCAGGAA AAGCCTCAGCCTTCGGTGAGGCGCAGAAAAGGGAAGTGTCCCTAGAGGGGGTGGGTGAGGGCGTGGGAGGTGGTGTCTGCAGGGAATGTCCCCTTTG GGGGAGGAGGATGGAGGGTTGGGATTCTGAGGATGGGGGGGGGGGCTGTAGCCAGCACCATGTCCCTCCTGTGTGACCAGCTCAGAGTCCCATGAAA TTGGGGCTTGGGAGGGGAAGGGACACTGGCCTGGGAACCAGAGACCTGGGCTGGTCTGGCTCACAGTTGCTGGACCTCTGTGATCCGTGTCAAAAAA CGAGAACACCAATTCCTGTCCTGCCCACTCACCACCAGGTGGGACCTGAACCCTGGCATCGCCAGCATTGGGAATGTCGGCCACTGACTCAACCACT CTCCCGGAGACCTATTTGGGCCACCCGAGGCGGGTGCCTGGGCCACACGGAGGGGTCCTGGTGGTCTTCAGGGCAGCGGCTGTGGGGCTGAAGCCTC AAGGAACCACATCTCTGCATAGGAGGGCCAGGCTGCAGGGCCTCGGAGACAACCTAGTTGGGCGTGTTGGGGTCTGTGGGTCCCAGGTCCTGGCCTC ACCGGGTCCCCACCGCGCTGTCAGCTCCCAGCCTCTTTCCCTCGTCTGCCTCTGGGCTTCTGTAAGGCTATGTGCTCCAAGGCCACCTCCTCCAGGC AGCCCTCAGACCCCCACCTTCGCCCAGTACCGATCTGCACCGTGGTCTCTGAAGTCTCCATCGTGACCTCAAACCTCGCTCGTCCTTGCTCCTAGCG AGGCTTGGGGTCGGGGTGTCCGAGGTGGGGGACATCCGGGGGGGTTAGGTGGCTGGCGCGGGGAGCCGGGGTTGTGAGGGGTGATGTCCTCAGGCGG CGGCGCTGCGGGGTGCGGCGAGGACACCGGTGAGGTGAGAGCACCGGCGGGGCAGCAGCGGGGGCCGCAGCGCCGGGTCCCTCGGCCCGGGGCCCCT CCCGCGCGGAGCCAGGGGCGGGACAGGGGGGCGTGGCCTGGTGGCGCTGACGTCACCTCGCCTATAAAATGTCCGGGGCGCCGCTAGCTGGGCTTTG TGGAGCGCTGCGGAGGGTGCGTGCGGGCCGCGGCAGCCGAACAAAGGAGCAGGGGCGCCGCCGCAGGGACCCGCCACCCACCTCCCGGGGCCGCGCA GCGGCCTCTCGTCTACTGCCACCATGACCGCCAACGGCACAGCCGAGGCGGTGCAGATCCAGTTCGGCCTCATCAACTGCGGCAACAAGTACCTGAC GGCCGAGGCGTTCGGGTTCAAGGTGAACGCGTCCGCCAGCAGCCTGAAGAAGAAGCAGATCTGGACGCTGGAGCAGCCCCCTGACGAGGCGGGCAGC GCGGCCGTGTGCCTGCGCAGCCACCTGGGCCGCTACCTGGCGGCGGACAAGGACGGCAACGTGACCTGCGAGCGCGAGGTGCCCGGTCCCGACTGCC GTTTCCTCATCGTGGCGCACGACGACGGTCGCTGGTCGCTGCAGTCCGAGGCGCACCGGCGCTACTTCGGCGGCACCGAGGACCGCCTGTCCTGCTT CGCGCAGACGGTGTCCCCCGCCGAGAAGTGGAGCGTGCACATCGCCATGCACCCTCAGGTCAACATCTACAGCGTCACCCGTAAGCGCTACGCGCAC CTGAGCGCGCGGCCGGCCGACGAGATCGCCGTGGACCGCGACGTGCCCTGGGGCGTCGACTCGCTCATCACCCTCGCCTTCCAGGACCAGCGCTACA GCGTGCAGACCGCCGACCACCGCTTCCTGCGCCACGACGGGCGCCTGGTGGCGCGCCCCGAGCCGGCCACTGGCTACACGCTGGAGTTCCGCTCCGG CAAGGTGGCCTTCCGCGACTGCGAGGGCCGTTACCTGGCGCCGTCGGGGCCCAGCGGCACGCTCAAGGCGGGCAAGGCCACCAAGGTGGGCAAGGAC GAGCTCTTTCCTCTGGAGCAGAGCTGCGCCCAGGTCGTGCTGCAGGCGGCCAACGAGAGGAACGTGTCCACGCGCCAGGGTGAGTGGGGACGCTGCC CCCGCCTCTCCTGGTCCGTGCACAAAGCGCACCCCACCCGCGCCCCTCCAGCCTCCCGCCCTTTCTCGCTCGCGGCGCCGCTGCGGTCCGGAGCACT GCCCATTGCGCCCCCGCTAGGCACGCGGGCTACCCCGCCTGGAGGGGGCGAGGAGTGGGGCTTTGCCCATCCTCGGGTGCCGCTGCCCACCTCCCAC CCCGGGCTGGGATCATGGGCTCCCCTAGGCCCCGCGGAGTCGCAACCGTACGTGCACCCTCCTAACCCCCCCCCCCGCCCAATCTTGGCTCTCCCCA CGCGCGCTGATCCCTCGGATCAGCTGTCCCAGCTCTTGCGGAGTGGGAGCCCCTCACCCATTTCCTCGTGCCCCTCCCCCCGCCGGCTGTCCTGGAG CTCGGGGGTCCGAGGCAAGGGTCGCCACCCGCAAGGGCGCGCCTCCACCCCCACCGGCAGCCTTTCGCGGGCGAGATGGGGGAGGTTAGCCAGGCCT TTGATCCCGGCGGGGCGCGCCTCCACCTCCCCGTCTGCCCGGCCTTCCTCCACCTCCTCCCGCTGCCGGGCGGGGTCGGCCTCCGCTGGTGGGGGGG GGCGCGGGGTGTCAGCCCTTCCCCCCAGCCCCTCCTCCCGCGTCTGCCCCGCGCTCGAGGCCGCGGCCTTTGTGAGCAGGGGGGCGGGTCGCCTCGA CTGGGTCCTCCCTCGCCCCCTTTGTCCTGCTCCATCTCTGCAGATGGGAAAACCAGATGCGGCGGGGCGGGGGAGGGGATCGGCTTTTGCGGTTCAC CCCTGCAGAGGAGCCCCCCGCGCCGCCCCCGGGCCCAGGGCTCGGGTCCCGAGGTTCCCCAGGAGGCGGTCTCCCTCCTCGCGCCGCGGCCCGGGAA CGGCGTGGCGCGGATGGCGGCCCTCCAGGCACCCCGCCCTTCGCCCGCCGCGCGCGTCTCCAGGCCGGTGCGCTGAGCTCCGCTCCGCGGGCGACCG AGGGCGGCTTCAGCGCGAGCCGGGAGACCCCAGGCCAGCTCCCTCGGGAAGCCCCTACCCTCTGGTGAACCCATCCCCTAGGGCGCTCGCCGGGAAC AATTGACTGCAACTCGATCCGTCCCCTCCGGGGCCTCCTGCAGGCACGGCTATTTGCGACCGGCCTGTGCGCCACTCTTTCCCTTCTTTCTCAGATT CTCCCCGAGGGGCTTTCTCTTCCTTTTGGCGTCCTCTTCCACTCCTGGCGGAGAAGCTGTTCCTTGCTTGCAGACAGAGGCCCCGCTGGAGGGAGGG GCGTGGGGGGATCTTTTTCCCTGGATAGGAAGTCGGACCCCAGGCCTTGGAGATGGCTGGACGGGAGCCCAGTTTGTGTCCTCATCCCTCCTCTTGG AAGGAGCCCTCCTGACGGCCCCCCTCTTGGCTGTGGGCTCTGCAGGAGGGGGAAAGACCCCCCATGGCAGTGGGGGTGAGGGTGGAGGCCTGGGTGG GGTAATGGCCATTTTGTGCCTGAAGTTTGCTACCTTAAGTCCCAGAGAGGTGAAGCTGCTTGTCATGGGTCACACAGCAAGTGACCACAAGGAAGCA GCATGCAGAAGTGGGTGCATTTGGCTCCAGAAACCCCGTTTCCTGTTTCCCACAGCGCATGGCGGGCAGAGCTCCTCACCTGATCAGCAGGCATTGA GCCCTACTAAGGGGACCTGCTGAGCCATGAGTGAACCAGTGGGGTTCACGTTCTCTTGGGGACATTACGAAGTGTCAAGGAAAAGGCAGCGGGTACA GGTTATTAGATGGCTGAGTCCTTTCTGAGCAGGACATTTGAGCTGGCCTGAAGGATGAATAGAAGGTGGCAGGTATGGGGGGGGTGCTGTGTGGACC AGCGTTGTAGGCTGTGGGTGTCTCCTGTGCAAAGGTCTTATGGCAGGAAGGTACAGAGAAAGCCCAGTGTGGCTGGGAGGAAGCTTGTGAGGTCTGG GCCACGGGACCTTGGGTGAGAGCTTAGTGCAGGGCTATGGTCCTTGCCTTGGGGTTGCAGCCACAGCCTCCCGTGGGGAAGAAGTCGCAGAAGTAGG TGGCCTTGGCCCTGGGGGCCAGGAAGTTGCAGAGAGCCTGAGGGTGTTTTTGGCGAGCCTGGGCAGATAACTCCCCTCTCCTGAGAAGCTTGCTGGG GGCGTCTGGTGTGTGATTCAGGCTGATAGGGTGGGAGGAACCAGAAATTGCAGCCAGGAGAGGTGGTGGTGATGGCTCAGCTTGGAGTTGAAAGGGA TGTGGGACGGCGCGGGGGTGGGGGTACTTGGGGGCCGAGGTTGGGGCTCCTCTGGCCTCAGATCTTGGGGTCCTTATCTCGTTTCTATGTCAGCCAA CTCCCGGGGGGCTTTTGGGAACTGGAGTCTGCAGGGGTGGGCGTGGGGGGCGTGTCTGCAGAGGCCATTTTGGACGGGCCTGCGTGGCAAGGGGGAG GCGTCTGCTTCCGACACACATGCTGGGGAACGCCAGCCAGGAAGGGGAGGATCCGGACTTAGCTGGCAGGGGGGATGTGAATCATCTCTGCAGGCCT GCACGGGCGGGCCCGGTGGGGGCAGGGTGCTCCCCTTTGAAAAACGCTGCGCCCTGCTCTTCAGCCTCAGTTTCCCCATCTGTAAAGTGTGCATTCC AGGCCTCCTTGGGCTGGCCCAGAGCTGCCCTGGGCAGGGGCTTTCAGCCCTTCACACCAGAGGCTGGGTCAGCTGAGTGAGTGCTCCTTTGTCCTCC CGCCATGCCCCAGGCTCCTCCCTGCTCCCCAGGATCCACACCTACCCTGGCCCCGACCCTGGGCCATGCCTCACCACACTTCCTGTCTTCTCTCACA TCTCTCACATCTGGGAGTCCTCTCCCGCCAGCCTGTGCTTGCATCTGGGGATCCATGCCAGGGATAGGACCTGTCCTCCCTGCTGGCTTGGGACATG CCCTCTCCCAGCCACTCTGAGGAGGGCTGACTGAGGAAGGGCTCGTCAAGCTGGGCTTTGCAGGATGTGTAAGAGTTCTCCCCACGAGGCGCAGGGC ATTCTGAGCCCAGGGAATGGCTTGTATAAGGATGCAGAGGCATTTGAAATGGCCAAGTAGTTGCAGGAATCGACTGGAAACCGGGGTGGTAAGGTGA AGCCATAGAACATTCCAGGCCCCCTCCCCTAAATGAGATGGAAGGAGTGCCTGTTTTGAACAAGCCAGGGGCATCTGGGGACCGTTAAGGCCTGGGG GTGGTGATGGGGACTGGAGGGTGTGAGGCAACCAGGGGGTGCCCCTCTGAGCCACCACAGACAGAATGGTTCAGAAGGCCAGGCACACTGGCTCTCG CCTGTAATCCAAGCACTTTGGGAGGCCAAGGAGGGAAGATGGCTTCGGCCAAGGAGGGAAGATGGCTTCAGCCCAGGAGTTCAAGGCCAGCCTGGAA AACATGGCAAAACCTCTGTCTACAAAAAATACAAAAAATTAGCCAGGCATGGTGATGCACGCCTGTCGTCCCAGCTACTCAGGAGGCTTAGATGGGA GGATCACTTGAGCCGGGGAGTTTGAGGCTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAACGAGACCCTGTCTTAAAAAAA TTTTTTTTGGCCTGGTGCGGTGGCTCACGCCTGTAATGCCAGCACTTTGGGAGTCCAAGGTGGGTGGATCACCTGGAGGTCGGGAGTTTGAGACCAG TCTGACCAACATGGAGAAACCCCATCTCTACTAAAAACACAAAAATTAGCCGGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTCTGGAGGCTGA GGCAGGAGAATCCCTTGAACCCGGGAGGCGGAAGTTGCAGTGAGCCGAGATCGCACCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCT CAAAAAACAAAACAAAACAAAAAAAACAACCAAAACAAACAAACAAAAAACTGTAATTAAAATAATTAAAAGAAAAAAGTTAAAAAAAAAAAAAAGA GAGGATGGCTCAAAGGCTGGAAACAGGGAAGGCCACTGTGAGGGGAGGACAGGCAGGGCTAGACCTCTCTGGAAGGAGGAGGGAGAGGTACCCGTGG GCCCGGCACAGGAGACTCTTAATCTCCTGGCTCCCGGGGGCTTCTGTGGGCCTGTGACTCAGGATTTCTGTGCCTCTGTTGATGAAAAGAAAAATCC TGAAGAAAACACTGTTCCCATAGTAACACAGCTCTAATTAGAGACTCCAAGGCCAAGCGAGGGCCTTGGAGCCAGGAGGGGCCCTGCTCTACTGGGG GGACGACACCCCTTTCCCCTATCCCTCCCTGCTGGGGTGTGGCCTGATGTCTACGTGGCACCAGGCCCCTAAATCCTTTCAACATCCTGGCGGAGCG GAGAGGCTGGGCCCTTTTGACAGGTGGGGAAACTGAGGAAGGTTGCAGGGAAGGCACTCATCCAAGGGTGCCTGGCCCCCCGCGGTGGGTGCCTCAC TGGCTGGCCTAAACCTTTGCATCAAACCAGTTCCAGGATTGAACGCAACAGGCTGATGGGGACTGAGTCGTGGTACAGATGGCGGCAGTTGTGTGGC CCTGGGCCCAGGAATGGCTGGGAAGCTCCCTTTCTTCTCTGGCTTGGGGGATGAGGTTAGTGTAAATTTCATGGAGTTGCCAGGAGGATTAAGGCCG ACGTGCATTCACACGTGGCCCCGTGGCTGCCGCCAGTTAAGCCCTGCGCAGCCATTGGAAGTCTCATTGAGAAGGAGCCTCCCGGCTTCCTGCATTT GTTCCAGGCGGGCTGGTAAGCGCCCTGCTTATTTGCAAGGCTGTGTGAGGACGAGCCCTGTAAACCCTAGGACGAGGCTGTGCTAATGTGGTTTCTG TTCCACTGTCTCCCCTTCTCCTTTTGCCCCTCTTTCTGGGGAACCTGGAGCCCCTGATGCCCTCTGTTTTTTCCTGCTGCTGGGGTGGACCTAGAAC CTCTCCCTCCATCCTTTCTGCTGCTGGGGTGGGCCTGCAGGAGGCTGTCCTCTTACCTGGTCCCTAACTTCCCTCCGATCAGCGGGGCTTCAGCGGA GCCCCAGCGCATTGGACAGGTGGTGCTCTGTGGCCGGCACAGGCCAGGGCCCAGGGTGCGGCCCCTGCCTGTAGGTAGACATGCAGGCCCTTCTGAG CAGAATGAGGGGGCGGTGAGGGCAGCTGTGCGGGTGTGGCTGGCCTGACGGCTCCCTGCAGCCCTGCGGCTTCTGTGCAGTGGGGGTGGGGCGGGCC AGACCTTTGCAGGGCCTCTTGGCTGGTGGAGGGCTGAGTGAGCAGAGGCCCCAGCCCTCGTGTTCCCTGGGGTGTGGCCTTAGGATGGTCCCGGCAC CCTGGGGACCCAGCCCCTGCTCACCTTATCCTCCTCCCGTGCTTGGCTGGGGTGTGGTGGCTGAGCCAGCCCACCCAGTGCGGTGGATGCTCGTCGG AGGGCAGAGGGTGGGCTACCGGCTTAAGGGGCCCCAGGGAACCTGGGGGGTGGAGCCCAAGGGGTTCCAAGAAGGGGCGGGGCCAGGAACCCATAGA CAAGAGGGTGGGGCAGGGAAAGGGCGTGGCAAGAGGGCCACCCACCTCCGGTCCAGAGAGCCAGCCAGACCCTTACTTTCTCTTGCTGTGTGACCTT AGGCAAGGACATGCCACCACCGGCCTTAGTCTCCCTCTTTGTGAAGTAGGATGAAGATCCCCACCTGTGGAGCAGATGTGGGGCTGCATGGTTGGGT CAGGATGGAACAGGATGGGGAGGCCGGGCGTGGTGGCTTACCCCTGTAATCCCAGCACTTTGGGAGGCAAAGGTGGGAGGACTGCTTGAGTCCTGGA GTTTGGGCAACATAGCGAGACCACCCCCATCTCTACAAAATAATGTTAAAGTTAGCCAGGTGTAGTGGTGAGTGCCTGTGGTCCCACCTACTGGGGA GACTGAGGCAAGAGGATCCTTTGAGCCCAGGAGGTGGAGGCTGTAGAGAGCCATGCTTGGGCCACTTGCACTCCAGCCTGGGCAACAGAGCAAGACC CTATCTCTAAAAAAAAAATGGAATTGAGGATGTGTCCTCTGGGTGTGGGCTCTACCACCCACCAGCCTCCCTCTCCTGTGGGTGCTGCCTGCCACCC ACCGCTGAGGTCCCTGCAGCATCAAGGTGCCCAAACGAAGACACTCTCCAGCTCTGAGCCAGGCACCCATACAGAGCCCGGCAGACGCCTCTGCTGC TGCAGTTCTTAGAATCCAGAGCGCGTGGGGAATGTGAATTTGTGCTGCTGGAGCCAAACATCCCACCTCCAGGTTTTAGCTGGAGGAATCCATGTGG ATATGCAAAGCAATGTAGTTATAATGAATAGCAATTGTGGGCTGGGCGCAGTGGCTCATACCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTG GATCACCTGAGGTCAGGAGTTTGAGACCGGCCTGGCCAACATAATGAAACTCCGTCTCTACTAAAAATACAAAAAAATTAGCCGGGCATAGTGGCGG GTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTTCAGTGAGGCGAGATCGTGCCATTGCACT CCAGCCCGGGAGACACAGCGAGACTCTCTTTCTCAAAAAAAGAATAGCAGCTTTGCTATAGCTTAGGGGAGCAAAACCCGAAAGCCACCTTAAGTTT CCCGAAGATAGAGATCCCTGGGGTCCTATTCTGAGACAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGGATCTCAGCTCACTGCAGCCT CCGCCTCCTGGGTTCAAGCAATTCTCCTGCGTCAGCCTCCCGAGCAGCTGGGATTACAGGCGCCCGGCACCACCCCCAGCTAATTTTTTTTTTTTTG AGACAGAGTCTCGCATTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAAGCTCCACCTCCCGGGTTCACGCCATTCTCCTGCCT CAGCCTCCCGAGTAGCAGGGACTACAGGCGCCCGCCACCGTGCCCGGCTAATTTTTTTTTTTTGTATTATTAATAGAGACGGGTTTCACCGTGTTAG GATGATCTCGATCTCCTGACCTCGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCTTGCCTGGTCCTTTTTTTTG TATTTTTAGTAGAGATGAGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCATGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGA TTACAGGTGTGGGCCACTGTGCCCGGCCAGTCCCATTCTACTTTTTAGGGACATGGAATCATGTAAAGATGCCATACAGAAAACAGTATGCAAATCC AGAGACAGAGGACATCTGTGCATGTTTCTTTCTTTCTTCCTTTTTTTTTTTTTTTTTTTTTTTGAGATGGATTCTTGCTCTGTCGCCCAGGCTGGAG TGCAGTGGTGCAATCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGACTTCCAAGTAGCTGGGATTACAGGCATGC CCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGGCGGGGTTTCACCATGTTGGCAAGGCTGGTCTTGAACTCATGACCTCAGGTGATCCACC CGCCTCAGCTTCCCAAAGTGCTGGGATTACAGGCGTGAGCCGCCGTGGCAACCCGCATGCTTCTTATGTATAAGAAAAAAACAGCTAGAAAGTTGTG GGTTCACTGGCTGGGCACATGGTGGCTTGTGTCTGTAACCTCAGCACTTTGGGAGGCTGAGTTAGGAGGATCATGTGAGGCCGGGAGTTCAAGACCA TCCTAGGCAACATAGCCAGACCCTGTCTGTACCAAATAGAAAAAAAAATTAACTTGATGTGGTGGTGTGTGCCTGTAGTCTCAGCTATTTGGGAGGC TGAGGTGGGAGGATCACTTGAGCCCAGGAAGTCGAGGCTACAGTGAGCTATGATTGTGCCACTGCACTCCAACCTGGGCAACAGAGCAAGACCCTGA ATCAAAAAGAAAGAGATGTATTTGCCAACACAGGGGTGTTCTGCAGTGGGGTGGGAAGGGGACGTGTAGGACTTCATAGTTTCCTTTTTTTTGTTTT AGAGACAGGGTTTAAAAAAAAATTTTTTTTTTTTTTTTGAGGCGGAATTTCATTCTTGTTGCCCAGGCTGGAGTGATCTCGGCTCACTGCCATCTCC GCCTCCCAGGTTGAAGTGATTCTCCTGCCTCAGCCTCAGGCAATTTTGTATTTTTAGTAGAGACGGGGTCACTCCATGTTGGTCAGGCTGGTCTCAA ACTCCCGACCTCGGGTGATCTGCCTGCCTTGGCCTCCCAAACTGCTGGGATTACAGGTGTGAGCCACTGTGCCTGGCCCCTTTTTTTTTTTTTTAAG TAGGGTCTTGCTAAGTTGTCCAGGCTGGTCTTGAACTCCTGGTCTCAAATGATCCTCCTGACTTGGCCTCCCAAAAGGCTGGGATTGCAGGAGATAT GAGCCACCGCACCCGGCCCTTTTATAAGTTTTCTAAAGGAAAGGAACATGTACCATCGTGTTTTATTTTAATTTTTACATAGAAGCAGGAACAATAG CATGAACCCCCAGACACGGCCCCCCAAGATGCGCTGTTCCGCTGTGCTGCAGCCCCATTTGTCCTTTTCTATACCATTTTTGGTTGTATTTGAAGCA AATCCCTGACATCAGGGCATTTCATCCCAAAATACTTCCATCTGTGTTTCTAAAAAAACGAGGCCATTTTCTTATGTAACCACAACGTGATCAACAG TAATCAATGCTTAACATCTAATTCTGGGCCACGTTAAGACCCTCCTGATTGGCTCAAGAATGTCTTTTGTGCAGTTGGTTTCTTGATTCTTTTTGTT TTTTTTGAGACAGGGTCTCACTGTGTCACCCAGGCTGGAGTGCAGTGGTGCAATCACGGCTCACTGCAGCCTCAGCCTCCTGCCTCAGCGATCCTCC TGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGTTTGCACCACCACTCCCAGCTAATTAAAAAAAGTAATTTGTAGAGACGGGGGTGGGGTGGGGGT CTTGCTATGTTGCCCAGGCTGGTCTCAAACTCCTAGACTCAAACAATCCTCCTGCCTTGGCCTCCCAAAGTGTTGCGATCACAGGCATGAGCCCCTG TCCCTGGCCCCTATTATTTCTCTAACTGGGGAAAGTCATGTGGGAACAGATGTAGCTTGCCTTGGCCTCTGACCGGCCCTGCCTGCGTTCCTGGGTG CTCTCTGCTGCTTCTCATGTGTGCCACTGTGGGGACTCGGCCGCCCACCCCACCCCGTGGTGTTACCTTGCGTGTGTAGTTCTGTGAGCTCAGGGCT ATGGTCTGCCAGAACTAGGGGGCGTGGGGCCCCAGTACCAGCCCAAGGCCTCCTCTCTGCAGGTATGGACCTGTCTGCCAATCAGGACGAGGAGACC GACCAGGAGACCTTCCAGCTGGAGATCGACCGCGACACCAAAAAGTGTGCCTTCCGTACCCACACGGGCAAGTACTGGACGCTGACGGCCACCGGGG GCGTGCAGTCCACCGCCTCCAGCAAGTGAGTGCCTCGCTCCCACCTGTCACCGCCCCCACCACCTTGCCTGGGCTACCCCGCCTGACCCTGTCCCGC CATCCCCCAGGAATGCCAGCTGCTACTTTGACATCGAGTGGCGTGACCGGCGCATCACACTGAGGGCGTCCAATGGCAAGTTTGTGACCTCCAAGAA GAATGGGCAGCTGGCCGCCTCGGTGGAGACAGCAGGTAACACTAAAGCCCCAGTTCCCTGGAGCCGTCCTGGAGTCCTGGAGGGTCTGGCCATGCCG TGGTCACTTGGTAGCCCCAGCCAAGGCCTGCTCTGTGCTGGGCATCCCCCCGGACTGGCCCCGCACTGTCCTACCCTGGGGCTGACTGCTGTGTGAC CCCAGCTCCTGGCCCTCCCTCTCTGGTCACCCCAGCCTCCACCCCACTCCCTGCCAGGAGGCTCACTGACTCCCCTCTTTCTGGGACAGGGGACTCA GAGCTCTTCCTCATGAAGCTCATCAACCGCCCCATCATCGTGTTCCGCGGGGAGCATGGCTTCATCGGCTGCCGCAAGGTCACGGGCACCCTGGACG CCAACCGCTCCAGCTATGACGTCTTCCAGCTGGAGTTCAACGATGGCGCCTACAACATCAAAGGCAGGTTCTCCTGTGGGCAGCTGCTGGGCAGGGA ACCCCTCGGTCGGGGCTGGGGTCAGTGCTGCGGGGAGCGCCCTCTGCATCCACACTGGACCCTGGCTTGGCTCAGGGCCATTCCAGGCCCTAAAGGG ACAGGTGTCTGATGGCCACCAGGGGCTCTGGGATGCAAGCAGCCCCTTTCCCTCTTGTCTGTGTGGTTGGGGGGACTTACCTTGCCCACCTGACAGA GAGGTGTGTGGAGGGGAGAGCAGGGAGGGGAAGGAGAGCAGGGAAGGGGAGGGAGGAGAGCAGGGGAGGGGAGAGCCGGGAAGGAGAGGAGAGCAGG GGTGGGGAGGTTCTGGAAAGGGTGTGCAGGGGAGGACGCGCCTCGGTTATGGGACTGGAGCCCCTTCCCAGGAGGACCCCCAACAATCCAGAGGTGC CTGTTAGGATTCAGAACATGGTTTTTTTGTTTGTTTTTTTGAGACTCACTCCCTCACCCTGGCTGGACTGCAGTGGCGTTATCTCGGCTCACTGCAA CCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACCACCACGCCTGGCTAATTTTTATATTT TTAAAATTTATTATTTATTTATTTTGAGACCCAGTCTGGAGTGCAGTGGCGTTATCTCGGCTCTCTGCAACCTCTGCCTCCTGGGTTCAAGCGATTC TCCTGCCTCAGCCTCCCGAGTAGCTGGGACTATGTGTGGGAGCCACCATGCCTGGCTAATTTTTTTGTATTTTTCATAGAGACGGGTTTCACCATGT TGTCCAGGCTGGTCTTGAATTCGTGGCCTCAAGTGATCCGCCCACCTCAGCCTCCCACAGTGCTGGGTTTATAGGTGTGAGCCACCACACCCGGCTA ATTGTTTTGTATTTTTAGTAGAGACGGAGCTTCACTATGTTGGCAAGGCTGGCTCGAACTCCTGACCTCAAGTGATCCGCCCACCTCAGCCTCCCAA AGTGCTGGGATTACAGGCGTGAGCCACTGCGGCCGAGCAGAACACGTTCTAGGACCCTTGTTCATGTGTCCATCATGGACAGGAGGACGTGCGGGCC ATAGGGACCCTGGCTCATTCCGGAGCCGGGACTGGAGGGTGGGGCGTCACCCTTGGGAACACCCGTGCCCACCCTCCGCTGCCCAGGGTAGGGGTGG GGAGCCAGGCTTTGGGCCCCACTTGATAAAGTCCCCTCCCCAGACTCCACAGGCAAATACTGGACGGTGGGCAGTGACTCCGCGGTCACCAGCAGCG GCGACACTCCTGTGGACTTCTTCTTCGAGTTCTGCGACTATAACAAGGTGGCCATCAAGGTGGGCGGGCGCTACCTGAAGGGCGACCACGCAGGCGT CCTGAAGGCCTCGGCGGAAACCGTGGACCCCGCCTCGCTCTGGGAGTACTAGGGCCGGCCCGTCCTTCCCCGCCCCTGCCCACATGGCGGCTCCTGC CAACCCTCCCTGCTAACCCCTTCTCCGCCAGGTGGGCTCCAGGGCGGGAGGCAAGCCCCCTTGCCTTTCAAACTGGAAACCCCAGAGAAAACGGTGC CCCCACCTGTCGCCCCTATGGACTCCCCACTCTCCCCTCCGCCCGGGTTCCCTACTCCCCTCGGGTCAGCGGCTGCGGCCTGGCCCTGGGAGGGATT TCAGATGCCCCTGCCCTCTTGTCTGCCACGGGGCGAGTCTGGCACCTCTTTCTTCTGACCTCAGACGGCTCTGAGCCTTATTTCTCTGGAAGCGGCT AAGGGACGGTTGGGGGCTGGGAGCCCTGGGCGTGTAGTGTAACTGGAATCTTTTGCCTCTCCCAGCCACCTCCTCCCAGCCCCCCAGGAGAGCTGGG CACATGTCCCAAGCCTGTCAGTGGCCCTCCCTGGTGCACTGTCCCCGAAACCCCTGCTTGGGAAGGGAAGCTGTCGGGTGGGCTAGGACTGACCCTT GTGGTGTTTTTTTGGGTGGTGGCTGGAAACAGCCCCTCTCCCACGTGGCAGAGGCTCAGCCTGGCTCCCTTCCCTGGAGCGGCAGGGCGTGACGGCC ACAGGGTCTGCCCGCTGCACGTTCTGCCAAGGTGGTGGTGGCGGGCGGGTAGGGGTGTGGGGGCCGTCTTCCTCCTGTCTCTTTCCTTTCACCCTAG CCTGACTGGAAGCAGAAAATGACCAAATCAGTATTTTTTTTAATGAAATATTATTGCTGGAGGCGTCCCAGGCAAGCCTGGCTGTAGTAGCGAGTGA TCTGGCGGGGGGCGTCTCAGCACCCTCCCCAGGGGGTGCATCTCAGCCCCCTCTTTCCGTCCTTCCCGTCCAGCCCCAGCCCTGGGCCTGGGCTGCC GACACCTGGGCCAGAGCCCCTGCTGTGATTGGTGCTCCCTGGGCCTCCCGGGTGGATGAAGCCAGGCGTCGCCCCCTCCGGGAGCCCTGGGGTGAGC CGCCGGGGCCCCCCTGCTGCCAGCCTCCCCCGTCCCCAACATGCATCTCACTCTGGGTGTCTTGGTCTTTTATTTTTTGTAAGTGTCATTTGTATAA CTCTAAACGCCCATGATAGTAGCTTCAAACTGGAAATAGCGAAATAAAATAACTCAGTCTGCAGCCCCAGGCCGGCCTGTGTGTGTCTTGGGGCTGA GGTGGGTGGGGGGGCTGAGGTGGGTGGGAGGGCTGGCGGGACAGGTAGGCGCCCTGGCTCCCCAGCTCAGTGCTGGGAGTGTGCAGTGGGAGGGAGG CCGTGGCTCCAGTGGGTGCTCCGGAGCTCGTGGGCCCAGCACACCTCCTTAAGCGGGGGATGGAGCGCTGGGAGGGGGTGGACTGTGGCCCATGCGA CCCCCAGAGCCATTAGGAGGAGTTCTGTGGTGAGAAGTGGCTGTGGCTCCTCGTAGGCTACGTCCACCATGCGGGGGACCTCGGGGGTGTCTGGCGG TGGCACGCTGGATGTTGAGAAGGCGCAGCCCAGGGAACACTCAAACCAGGAGACCCCACATTATCCTCTAGTTGACATGTGCCCTTCGACTAGGGGA CTTGGTGGTAGGGGCAGCTCCGCCCCCATACTGCGAGGATCCGGGCCTTCCACTTCCCCAGACACAGCAGGTTGGGGTGCCCCTGGGGCTGGGAGAT GCTGCCCTGGGCCCCTCAGGGGGCGGCCGTGGTAGGATGGACCGGGCCGAGCGTGCAGACCCTGGGCAGGTCCCTACATCGGAACCAGCAGCCCTGG GGATATCTGGCATATCAGAGGCTGAGGACTGTTTCCAGACTTTACCAAGGCCACAGTCAGGGCGACCTGGGTTCTGAGCCTCCCTTTGCATCCTAGG CTGCAGGGACAGGGGCTGGGCAGAGGCTCGCGGACCTCGTGCAGCTTCATTCACTCCCAGGTGCCCCTAAGGATAGCAGCTGCGAGAAGACTGAGGG GAGGAGCAGTAAGGCGCAGCCTGGAGCGGAGGGACCTGGCGTCCAGTCATTGTGCGCTGGGAAGGCGGTGATGGCGACGGAATTTGGGACACGCGGG GCGTCCCGGGGGCAGCCAGGGCACTGCAGGCCGGAGCCCCCTGTTCCCCCGCATCCTCCCCGCCGTCGGCAGCAGAGCAAGCGCTGATTGGCTGCTG ATGACGCAACTGGGAGGGCTGCGCTGTGATAGGTGGTCCCTCGGGGGCGTGGGGCGCAAGTCTTGAGATTGGCAGGGGCAGGTGGCTGCTGCAGAGG GAAGTCGGGGTCACCTCAGCGAGGTTCCGGCGGCCACCCCTCTCCCCTCCCCCATGAAAGCCAGGCTGGAAGCCAGAAAAATCCCAGTGACTGGAAG GGACAGATTAATCCTCCGGAACCAAACTCTTTGAGACCTGGGGAGGAGGGTGGGAGGCACTGGGAAGGGGGATTGGGGGGAGCCTGGCTCATTTCCA CCCATGGAGCTGACCTAGAATGACCCTAAGGTCCCCGGAGCCACCAGCTGATTCCGAATTCCATTCATTCTGCAAAATTTGGCGCCTACCACGTGGC CGAGATTCCCGAGGCTGCAGCCAATGAGCAGCATAGTCCGATGGGGGAGGCTGGAAGGGCCGTTCACGAGATCTCTCGGGAGGAATCGGTAGGAGCT GCCCAACTGAAAGGGACGGGGGAATAACCCGGGGCGAGGGACCTGCCCAGGCCCTGCCCTCTGGGGGGAAGCCAGGCCAGGGGCCGGGGGCATCTCT GGGGTCCCAGGTGAGATGCGGGTCGAGGGAGCCAGGCCACGGTTCTCCAGACTCGCGTGGAGGCCACGAGCGTCTTCTGGAGGAGCGGGCACTGCGC GGACCGGCAGACTCTGGGGCGCTCGTGCTCCCCATCTCCTGACCTTTTCCTACCTTCAGTTCCCTCGTGTCAGGACAGGTTCTGGGGCTCGCCGGGG CAGGGAGCCAGGGCAGAGGGTGCAGTTTCCGCTCCTGCCTGAGTCACCTTCGCTTTCTCAGCGATTCTTCATTCACAAGGGCGTGGCCCATCACACG CACTCACACACTTGTGAACTTGCACGCACACACACATATGGACCTGTGCAAAGAGCCCCATGCACAGGCAGGTACACGTGCATGTAGGCGTGCACAC AGACACGCACAGATGCAGGCAGACCAACTCCCAGGAATCTGTCTCCAGCCTACAGGGATTCAGCACTCAGGGTACCAGCCTCTGTCCCGTGCACCCC CATTCCCGGCAGTTCTCCCAGGTGGGTCGGGGGCCACTAGGGACCCCATACCCCGAGGGTGGCTCCTCCATTAAGCCTGCCATGGGGTTGGGAGTGA GAGTCCCACCTCCCACTTGAGAGTCCCCAGTGAGTCAAGGCAAGTGCAGCCAGGGCTCCAAGATCCTTGTTGGGATTCACTGTGATCCCCAAAGATC ACGACTTAAGGGAAAACATTCAATTAAACTTGTTAGAGCAAAGAAAGGAGAGACTGGGCTGGGAGCAGTGGCTAACGCCTATATAGTTCAGCTACTC AGGAGGCCCAGGTGTGAGGATTGCTTGAGTCCAGGAGGCTGAGGCTGCAGTGAGCTATGATGGCACCACCCACTGCACTCCAGCCTGGGTGACAAAG CAAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAGGAAAAAGAGGCCGGGCACAGTGGCTCACACCTGTAATCTACTAAAAATAAGAAAA TTAGCCAGACATGGTGGTGGGTGCCTGTAATCTCAGCTACTTGGGAGGCTGGGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGTGTGAGCC GAGATTACACCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTCTGTCTCCAAATAATAATAATAATAATAATAAAATAAAAAGAAAAAAGAAAGA AAGAAAGGAGAGACTGAGCTATATTGCCCAGTCCAGGCATGTGGGCAGTCTGGGGGACAGTGGGGCATACTCGGTGTCTCAGGGTCCCAGCCCTGGG TGCCCCCACTGCTGTCTGCTGTGACCTCCTCAGGAGGCCTCATTGGGAGGGACCCTGAGTCCTGCGGGGGGCTGTGGAGCTGTCACCAGCCCCAGGA GGACTCAGGCAAGTCCCTCTGGTGGTCGAGGCCTCTGAGCTTCCCAGTGTGTCTCCACGGGACACCCCCCCTCCAGACCTTCTGCCCCAGCTCAGCC TCTTCCAATTCATTATCAGGGGGTGGGGGAGGGGACAGGAAGCCCCAGACCCAGCTGGGCCCCATTTCCTCCAGGGCCACAGTGGCCTCTCCCAGAG TCACGAGCATGGGGGCTGATCTCACTCTTTTTTTTTTTTGAGACGGACTCTCACTCTGTCGCTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTC ACTCTGTCGCCCAGGCTGGAGCGCAGTGGCGTGATCTCGGCTCACTGCAATCTCCACCTCCCACGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAG TAGCTGGGACTACAGGTACGTGCCACCACACCTAACTAATTTTTGTATTTTTTAGTAGAGATGGGGCTTCACCATATTAGCCTCCCAAAGTGCTGGG ATTACAGGCATGAGCCACCATGCCCGGCCTTGACTTCACTCTTTTAAAAAAGTCAAATACTTGGTGCTTGAAATCCCAGCACTTTGGGAGGCTGAGG CAGGAGAACTGCTTGAGCTCAGGAGTTTGAGACCAGCCTGGGCAACATGGTGAGACTCCTGTCTCTGTAAAAACTACGAAAATTAGTCAGGCATGGT GGTGCGTGTCTGTCGTCCCAGCTGCTCAGGAGGCTGAGGTGGGAGGATGGTTTGATCCTGGAAGGTTGAGACTGCAGTGAGCTGTGATTCCACCACT GCAGTCCAGCCTGGGCCGCAGAGCAAGACTCTCTCTCAAAAATAAATAAAATAAAATAAAAAGTCTAAAACTTTTCTTTCAAACGACGGCTTTTGGG GCTCATAAGGTGCGTGAAGATGGAAAGGGGGCCCGGCAGTGCCCATTTCGGCTCCCTTGGGACCCCGGCTTCCCTGAAGACCCCTGAGCAATGGTTG GCTGGGTGCCTGGTCTCCCTGAACGGGCTGTGGGCAACAAGGTTGTCTGGATGGGGGAGGGGCTCTGAGACCCTTGGGGGCAGCAGAGGGAGAAGGG AACAGATGGGGTCTCCCAGGCAGAGAGGCCTGGAGGGGTGGGGCGGGGCAGGGCATTTGGCGTGAAACCCAAGCCCCTTAACGGGGCCCTAGCTTAA ACCGGGAGGAGGGGCCTCTGTGATGTGCAAATAATTAACACAGAAGCCTTCACTGTGCTCCCCTCCTCATCCCAGGACCCAGGTCTGACCCTCAGGA GGGGAGGAGGTGAGCAAGGGGGGAACCCACCTTCCAGGGAACCCCCAGATAGTGCCAGGCACCAGGCAAGTGCTCTAAAAGGCTTTACTAATATTAT TTGAAGAAACTAAGCTAATAAATAAATACGGTATAAAATCAAAGGGTACCCACAGATATAAACAAAAATCCACAGCTAACCCGGCCCCAGCCCTCTT TCCTTTGGAGGTAACTGTGTTAATGGTTTTTTACACCCCTCTGGAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGAAGGAGTCTGGCTC TGTCGCCCATGCAGCGCAGTAGCGTGATCTCGGCTCACTGCAACTTCCACATCCCGGGTTAAAACGATTCTCCTGCCTCAACCGCCTGAGTAGCTGG GACTACAGGGGCGCACCACCATGCCCGGCTAATTTTTTTTTTTTTTTTTTTTTTTTTTGAGCTGGAGTCTTGCTCTGTCGCCCAGGCGGGAGTGCAG TGGCGCAATCTCGGCTCACTTGCAAGCTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTGGGTGGGACTACAGGCTCCAGCCA CCACGCCCGGCTAATTTTTTGTATTTATTTTTTAATAGAGATGGGGTTTCACTGTGTTCGCCAGGATGGTCTCGATCTCCCTTTTTTTTTTTTTTTT TTTAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCATGATCGTGACTCACTGCAAACTCCACCTCCCGGGTTCACGCCATTCTCCCG CCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCACACCCGGCTATTTTTTTGTATTTTTAGTAGAGACAGGGGTTTCACCATGTTAGC CAGGATGGTCTCGATCTCCTGACCTTGTGATCCTCCTGCCTCGGCCTCCCGAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTCTTGTT TTTTTTTTTTTTTTTTTTTATAGACTTCTAAGGAAAGCAACACTAAGAAAATATATTTTTAAGAAATTATTCAGCCAGGCGTGGTGGCTCACGCCTG TAATCCCAACACTTTGGGAGGCTGAGGCGGGTGGATCACTTGAGGCCAGGAGTTTGAGACCAGCCTGGCTCACATGGTGAAACCCTGACTCTACTAA AAATACAAAAAATTAGCCGGGCACAGTGGCATGCTCCTGCAATGCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCCCTTGAACTGGGGAGGCAGAG GTTTCAGTGAACCAAGATCGAGCCACTGCACTCCAGCGTGGGTGACAGACTGAAACTGTGTCTCAAAAAAAAATTTTTGTTTTTGGAGATGGGGTCT TGCTCTGTCACCCAGGCTGGAGTACAATGGGGTGATCTAGGCTCACTGCAACCTCAAACTCCTGGGCTCAGGTGATCTTCCTGCCTCAGCCCCTGGA GTAACTGGCACTACAGGTGCATGTCAGAACACCTGGCTAGTTTTTAACTTTTTTGTGTGTAGACAGGGTCTTGATATGTTGCCCAGGCTGGTCTCCA TCACCTTCTGGGCTCAGTGATCCTCCTGCTTCAGCCTCCCAAAATGCTGGGATTACAGGTGTGAGCCACCATGCCCGACCCTGAGGGATACCTTAAT GTTTATTTCTCACATTTCTTCTAGAACAAACATTGCCAGCGCATCCCAGACTCTGAACTGTGGCTGGGGACTGCAGCATGGAGGTCTTTGCAGGCAC TCTGGGAAACATGCCACAAGCAGGGTATTAACCCAAGACAGTCAGTCCCTCCAATGAGAAAAAGGAGCCGAGGGACTGTGCATGCCTCAGAGCCAGA TGCAGCAGAACTGGTGGGTTGAGGGGGCACTGAGCGCCTGGTGCCTCCTGCTGCCCCCCACCAGCTCCGACAGTCCTCGTCCTTGTCCTCCCCATCA GAAGGGAAGAGTGAATTGTCTGTGGGATGTGCCAGTGTCCCCGGTTCTGAGGTTGGGCAGGCTGGGGAGCCCCAGACATGGCTTGCTGCCCACTGTG GAGCCTCCTGGACTTAGTTCCAGGCTCTGCCCGATCCTCTGAGGGTGTGGCTTCAAAGCCCTGCTTGGGCCTAAGGCCATCCCAGGGCAGTGACTGA GGGTAGACTGAGATGTCCCTTGGGCACCAGTCCTAGGGTACCTGGGCTGGGGGTCTTCAGCTCAGGCCCCCTAGTGCCCGTCCTTTGGGCTGTGGGC AGGTTTCCACAGCACTGGCCCTTTCTGACCTTACACCCCTGTGCATCCTCACTGGGGCTCTGTGAAGGTGAAAGTCACACTAAGGACTGTGCCTATG GTGGCCAGGGCACCCCACCGGCAGCACACCTCAGAGGCCTCATCCTAGGCGCTGCTCACTTTTTTTTCTTTTTTTTCCTTTTTTTTTTTTTTTTTTT TTCCGAGACAGAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCGACCTCCTCCTCCTCCTGGGTTTAAGCAATTC TCTTGCCTCAGCCTCCTGAGTAGCTGGCATTACAGGTGCCCGCCACCACGCCCGGCTATTTTTGTAGTTTTAGTAGAGACGGGGTTTCACCATGTTG GCCAGGCTGGTCTCAAACTCCTGACCTTGTGCTCTGCCCGCCTTGGCCTCCCAAACTGCTGGGATTACAGGCGTGAGCCACTGTGCGTGGCCCTGCT CATTTTCTTACCACAGCTTTCCAGAAATAAAGTTAGGATGGAAAGAGAGAGAGAGAGATTGAGAGAGAGAGAGAGCACCACATTCAGATAGAGACAG GAGAGTTCTCAGCAAGAAGAGAACTCAGCTCAGAGTTGAGAATGTCTCAACTCAGCTGTCTCCCTGCTGAGACGTCCTGGGCTGAAGTGTCCCCTCA CCCCTGCGGGGCTGTGACTGCACACTGCACACATGGGTCACAGCAGGGCTTGGCGTTTGGAGCAGGCCGGGTTGGTGGCTTGTCCTCATCTCTTGCC TGGAGCTGTGCTGGCCTGTGGTTTGCTTTGGCTGCTACCATGTGGAGGGAGAGGTGCTTGTGTCCATGCCTGGCCTCTTGGAAGGCCACCACTGTGA TGGAGAGAGGAAGGCCACCACTGTGATGGAGAGAAGCCGGGGCCAGACCGATGAGGGCTGAGAGCCCATGGGCAGGGGTTGTGGTCTCGGCCAAACC CCAGCTGGCAGCTGATGGCAGCCACCCCGGGGTCCTCAGATATGGCACAGCTGCCTGGCTGAGCCTCGGCAAAGGGAAGCCTTGTGGAAAATAGCAA CTCAGGGATGTTGTGAGTAGTGGGCTGAGCTGTGGTTTATTTTTTAGAGACAGGGTCTTGCTCTGTCACCCAGGCTAGAGTCCAGTGGTGTAATCAT AGCTCACTGCAGCCTTGACCCCCCAGGCTCAAGTGATCCTTGTGTCTTGGCCTCCTGAGTAGCTAGGACTATAGGTGCATACCACCATGCCTCGCTT GTTTTTTGTTTTGATAGAGATGGGGGTCTTGCTAGGTTGCCCAGGCTGGTCTGTAACTCCTGGGCTCAAGTGATCCTCCTGCTTTGGCCTCCCAAAG TGCTGGGATTACAGGCGTGAGCCACTGTGCTGGCCTTGGGGTGTGGTTTTATGTGGCCATAGATGACTGAGATGGGTGAGAAGCGGGACCTAGGGGA ATATACAGGGCAGGGGGATCCGACAGGGGGACAGGAGGGCAGACAGCTCCTGGAAGGCCTGGGAAAGAGATATCAGGGCTGGACCCTGGAGAAGTGA GGCTTTGAGGGAGGGGAGGAGATGGGGCCTGGCGGGGTACGGGCGCTGCTCCTAGGTCTGAGGGCATCGGCGGTCTGAGAGCTTGCGGGAGGGAGGG CTGCCTCCCGGTGCTCGGTGCCCTGGCTCTCCTCCTTGCTGCTGGCTGGCCTCCTCCTCCTCATGCATCTGTGTGTCCTGGAACACAGGGCACTGTC CCTCTGCCTGTCCAGAAAAGCACGTGCTCCTTGGGGCCTGGCCTGCTCAGCCCTATGTCCCACCCGCTCCCTGCTGCTATTCCCAGGCCTTCGGGCC TCACTGCCTGGGGTGGCCGTGCTCAGCCCCACCCTGTGGTGCCATGGCCTCCCCACCCCTGCCCCGAACTGCCCCTGGGACCAGTTCCTTCAGCTCC CAGGACAGGGCCTGGCCATCCCTGTGGATTCTCCCTGTTCGTGGACCCCCATTGGTGCCCAGTCTCCTTGGACTGTCTTCTGAGCCTCTCTCAGATG TACCCCCAACTGTACCCTTTCACCCAGAGGCCATTTGGCAGCGTCCTCCAGGACTCCTGCCGTGGGGGAAGTCTCCACCAAGGCCAACGCGTGACTG CATCCCGAGGAGCTGATTTAAGATCTGGTTCTCAGGAACACCTGGAACTGGCCAGTCAGCATCCCCGGCCCTGCGGTCTGCACTTGGACAAGGGTCA GGCAATGAGGATGAGCAGCAGGCGGGGCTTCTCCTGGAAGCCTTCCCAGCCTCCTGGGCCACTCCAGTGGGTCCCCTCCACAGACTCAGCCTGTTCC CTGCCACCTGGTGCCGGTTTCTCEGTGGCACCTACTAGGGGCCGAGTGCCCCGGGACTGCCCAGCTGAGCAGCGCCGTCCAGGTCTGCACCCAGCTA CACTCAGGGCACGTGCACAGGTGAGCAGCCGGGCACGCAGGCACCTGCCAGGTGTGGGTGTGGACTAGGTGCTCCCGG HUMAN SEQUENCE - mRNA GCGGAGGGTGCGTGCGGGCCGCGGCAGCCGAACAAAGGAGCAGGGGCGCCGCCGCAGGGACCCGCCACCCACCTCCCGGGGCCGCGCAGCGGCCTCT CGTCTACTGCCACCATGACCGCCAACGGCACAGCCGAGGCGGTGCAGATCCAGTTCGGCCTCATCAACTGCGGCAACAAGTACCTGACGGCCGAGGC GTTCGGGTTCAAGGTGAACGCGTCCGCCAGCAGCCTGAAGAAGAAGCAGATCTGGACGCTGGAGCAGCCCCCTGACGAGGCGGGCAGCGCGGCCGTG TGCCTGCGCAGCCACCTGGGCCGCTACCEGGCGGCGGACAAGGACGGCAACGTGACCTGCGAGCGCGAGGTGCCCGGTCCCGACTGCCGTTTCCTCA TCGTGGCGCACGACGACGGTCGCTGGTCGCTGCAGTCCGAGGCGCACCGGCGCTACTTCGGCGGCACCGAGGACCGCCTGTCCTGCTTCGCGCAGAC GGTGTCCCCCGCCGAGAAGTGGAGCGTGCACATCGCCATGCACCCTCAGGTCAACATCTACAGTGTCACCCGTAAGCGCTACGCGCACCTGAGCGCG CGGCCGGCCGACGAGATCGCCGTGGACCGCGACGTGCCCTGGGGCGTCGACTCGCTCATCACCCTCGCCTTCCAGGACCAGCGCTACAGCGTGCAGA CCGCCGACCACCGCTTCCTGCGCCACGACGGGCGCCTGGTGGCGCGCCCCGAGCCGGCCACTGGCTACACGCTGGAGTTCCGCTCCGGCAAGGTGGC CTTCCGCGACTGCGAGGGCCGTTACCTGGCGCCGTCGGGGCCCAGCGGCACGCTCAAGGCGGGCAAGGCCACCAAGGTGGGCAAGGACGAGCTCTTT GCTCTGGAGCAGAGCTGCGCCCAGGTCGTGCTGCAGGCGGCCAACGAGAGGAACGTGTCCACGCGCCAGGGTATGGACCTGTCTGCCAATCAGGACG AGGAGACCGACCAGGAGACCTTCCAGCTGGAGATCGACCGCGACACCAAAAAGTGTGCCTTCCGTACCCACACGGGCAAGTACTGGACGCTGACGGC CACCGGGGGCGTGCAGTCCACCGCCTCCAGCAAGAATGCCAGCTGCTACTTTGACATCGAGTGGCGTGACCGGCGCATCACACTGAGGGCGTCCAAT GGCAAGTTTGTGACCTCCAAGAAGAATGGGCAGCTGGCCGCCTCGGTGGAGACAGCAGGGGACTCAGAGCTCTTCCTCATGAAGCTCATCAACCGCC CCATCATCGTGTTCCGCGGGGAGCATGGCTTCATCGGCTGCCGCAAGGTCACGGGCACCCTGGACGCCAACCGCTCCAGCTATGACGTCTTCCAGCT GGAGTTCAACGATGGCGCCTACAACATCAAAGACTCCACAGGCAAATACTGGACGGTGGGCAGTGACTCCGCGGTCACCAGCAGCGGCGACACTCCT GTGGACTTCTTCTTCGAGTTCTGCGACTATAACAAGGTGGCCATCAAGGTGGGCGGGCGCTACCTGAAGGGCGACCACGCAGGCGTCCTGAAGGCCT CGGCGGAAACCGTGGACCCCGCCTCGCTCTGGGAGTACTAGGGCCGGCCCGTCCTTCCCCGCCCCTGCCCACATGGCGGCTCCTGCCAACCCTCCCT GCTAACCCCTTCTCCGCCAGGTGGGCTCCAGGGCGGGAGGCAACCCCCCTTGCCTTTCAAACTGGAAACCCCAGAGAAAACGGTGCCCCCACCTGTC GCCCCTATGGACTCCCCACTCTCCCCTCCGCCCGGGTTCCCTACTCCCCTCGGGTCAGCGGCTGCGGCCTGGCCCTGGGAGGGATTTCAGATGCCCC TGCCCTCTTGTCTGCCACGGGGCGAGTCTGGCACCTCTTTCTTCTGACCTCAGACGGCTCTGAGCCTTATTTCTCTGGAAGCGGCTAAGGGACGGTT GGGGGCTGGGAGCCCTGGGCGTGTAGTGTAACTGGAATCTTTTGCCTCTCCCAGCCACCTCCTCCCAGCCCCCCAGGAGAGCTGGGCACATGTCCCA AGCCTGTCAGTGGCCCTCCCTGGTGCACTGTCCCCGAAACCCCTGCTTGGGAAGGGAAGCTGTCGGGAGGGCTAGGACTGACCCTTGTGGTGTTTTT TTGGGTGGTGGCTGGAAACAGCCCCTCTCCCACGTGGGAGAGGCTCAGCCTGGCTCCCTTCCCTGGAGCGGCAGGGCGTGACGGCCACAGGGTCTGC CCGCTGCACGTTCTGCCAAGGTGGTGGTGGCGGGCGGGTAGGGGTGTGGGGGCCGTCTTCCTCCTGTCTCTTTCCTTTCACCCTAGCCTGACTGGAA GCAGAAAATGACCAAATCAGTATTTTTTTTAATGAAATATTATTGCTGGAGGCGTCCCAGGCAAGCCTGGCTGTAGTAGCGAGTGATCTGGCGGGGG GCGTCTCAGCACCCTCCCCAGGGGGTGCATCTCAGCCCCCTCTTTCCGTCCTTCCCGTCCAGCCCCAGCCCTGGGCCTGGGCTGCCGACACCTGGGC CAGAGCCCCTGCTGTGATTGGTGCTCCCTGGGCCTCCCGGGTGGATGAAGCCAGGCGTCGCCCCCTCCGGGAGCCCTGGGGTGAGCCGCCGGGGCCC CCCTGCTGCCAGCCTCCCCCGTCCCCAACATGCATCTCACTCTGGGTGTCTTGGTCTTTTATTTTTTGTAAGTGTCATTTGTATAACTCTAAACGCC CATGATAGTAGCTTCAAACTGGAAATAGCGAAATAAAATAACTCAGTCTGC HUMAN SEQUENCE - CODING ATGACCGCCAACGGCACAGCCGAGGCGGTGCAGATCCAGTTCGGCCTCATCAACTGCGGCAACAAGTACCTGACGGCCGAGGCGTTCGGGTTCAAGG TGAACGCGTCCGCCAGCAGCCTGAAGAAGAAGCAGATCTGGACGCTGGAGCAGCCCCCTGACGAGGCGGGCAGCGCGGCCGTGTGCCTGCGCAGCCA CCTGGGCCGCTACCTGGCGGCGGACAAGGACGGCAACGTGACCTGCGAGCGCGAGGTGCCCGGTCCCGACTGCCGTTTCCTCATCGTGGCGCACGAC GACGGTCGCTGGTCGCTGCAGTCCGAGGCGCACCGGCGCTACTTCGGCGGCACCGAGGACCGCCTGTCCTGCTTCGCGCAGACGGTGTCCCCCGCCG AGAAGTGGAGCGTGCACATCGCCATGCACCCTCAGGTCAACATCTACAGTGTCACCCGTAAGCGCTACGCGCACCTGAGCGCGCGGCCGGCCGACGA GATCGCCGTGGACCGCGACGTGCCCTGGGGCGTCGACTCGCTCATCACCCTCGCCTTCCAGGACCAGCGCTACAGCGTGCAGACCGCCGACCACCGC TTCCTGCGCCACGACGGGCGCCTGGTGGCGCGCCCCGAGCCGGCCACTGGCTACACGCTGGAGTTCCGCTCCGGCAAGGTGGCCTTCCGCGACTGCG AGGGCCGTTACCTGGCGCCGTCGGGGCCCAGCGGCACGCTCAAGGCGGGCAAGGCCACCAAGGTGGGCAAGGACGAGCTCTTTGCTCTGGAGCAGAG CTGCGCCCAGGTCGTGCTGCAGGCGGCCAACGAGAGGAACGTGTCCACGCGCCAGGGTATGGACCTGTCTGCCAATCAGGACGAGGAGACCGACCAG GAGACCTTCCAGCTGGAGATCGACCGCGACACCAAAAAGTGTGCCTTCCGTACCCACACGGGCAAGTACTGGACGCTGACGGCCACCGGGGGCGTGC AGTCCACCGCCTCCAGCAAGAATGCCAGCTGCTACTTTGACATCGAGTGGCGTGACCGGCGCATCACACTGAGGGCGTCCAATGGCAAGTTTGTGAC CTCCAAGAAGAATGGGCAGCTGGCCGCCTCGGTGGAGACAGCAGGGGACTCAGAGCTCTTCCTCATGAAGCTCATCAACCGCCCCATCATCGTGTTC CGCGGGGAGCATGGCTTCATCGGCTGCCGCAAGGTCACGGGCACCCTGGACGCCAACCGCTCCAGCTATGACGTCTTCCAGCTGGAGTTCAACGATG GCGCCTACAACATCAAAGACTCCACAGGCAAATACTGGACGGTGGGCAGTGACTCCGCGGTCACCAGCAGCGGCGACACTCCTGTGGACTTCTTCTT CGAGTTCTGCGACTATAACAAGGTGGCCATCAAGGTGGGCGGGCGCTACCTGAAGGGCGACCACGCAGGCGTCCTGAAGGCCTCGGCGGAAACCGTG GACCCCGCCTCGCTCTGGGAGTACTAG

[0293] TABLE II MOUSE NOMENCLATURE ICSGNM      Map3k6 Celera      mCG20807 HUMAN NOMENCLATURE HGNC        MAP3KE Celera      hCG19300 MOUSE SEQUENUE - GENOMIC GGGCTGGACCTTCACAGAGAGGCAGAGCTACACAAGGCAATACCAATTCTCTGGGGCCTGAGGGAGGAAATGCCCCAAACCCTGCTGGCTCCAGTTG AGGTGGTGTGCCTCTGGGAGACAATGGGGAGAAGTCTTGCTTCAAGTTATTTCCCCCACAGCCTGATCCATCTATGCTGGCACCCCCCTCTAGTAGA CCCTACAAGATGGGTCTACTATGAGCCCTACTGTTCTAGCTGCTCCTATTTAAAGGGCTGCCTGCCTGAGGGTACAGGGTCACCCCAGCTGCCCATG TAGGGTCCTACAAATGCTCACCACATCAACCACTCATTCTCTCCTCATCTCAAGAAGCAGGGTGAGAGAGTTTGGTAATCTGGCCTTTTCATGTAAA TTTATGTAAATAGGATATAAATATCACAACATATGTAAATAGGATATAAATACCACAGAACCTCAGCATCTCAGGAGGTCCTGATATCTAGAATCTA GGAGGTAGAAGGAATGGCAGAAAAGTCTGGAGGAGATATGTTCGCCCTGTGCCCGTTGGCCCTGTGTTTCCATGTAGAACCCAGGGAGCTGGAGCTG GAGCTGGAAGCCAGCAAAGTGGTCCCCCTGCCCAGTTATTCAGGTGTCCCAAGAAGTCCTAGAGAGAAGAGATCTGTAGGTTCTCAAGGTAAGGGAT GTCAGGGACCTGGCAGAGAGGGCTCTCGAGGTAGCCTGTAGAGGCTGGATGTGGCTGCTTGGGTAAGAATGGCTCTCATAGGCTCATATATTTAAAT GCTTAGTTATTAAGGAGTGGTACTATTTAAGAAGGATTAAGAGGTGTGGCCTTGTTAGAGGAGGTGTGTCACTGGGGGTGGGCTCTGAAGTTTCAAA AACCCAACTCTGTCTTCCCTCTGCATGCCTTTGTGTGTATCTTTCTGTCTTAGGATCAGGATGTAGCCGGAAACTACTTCTCCAGCAGCATCCCTGC CTCTGTGACCTCGTGCTCCCCACTATGGTGATTGTGGACTAAACCTCTGAAACTGTAAACAATCCCCCAGTTAAATGATTCTCTACAGGAGTTGCTG CCTTCGTGCCCAGCACTCAGGAGGCAGAGGCAGGTGGATCTCTGTGGGGTCAAGGCCAGCCTGGTCTACAGAGTGAGTTCTGGGACAGCCAGGGATA TACAGAAAAGCCTGTCTCAACAAACAAACAAACAAATAGGAAAGGTAGTCATGGTCATTGTGTCCCCTCCCAGCAATAGAACACTGACTAAGACACT GGGGTGCAGGTGCTGAGTGTGGACAATGACGACGTGGGAACCACCTCTGCACCAGGCTCCAAGTGGGAGAGTGCCAGGATCCTGGGGTGTACCAGGT AGATTGCATTGTTCATGTTTTACTGCAGAGGACTGTGAGGCTCAGAAAGGAACAATTGCTTGTCCCCAATACAGAGCCAGAAAAGGATGCTAATAGG TGAGAACACCAAATTCTGTTTCCTCCTCTTCCTCTTCTTCCTTCTCCTCCTCCTCTTCCTCTTCTTCCTTCTTCTCCTCCTCTTCCTTTTGTCTTGA GCACTGGGCAGGACACAGGACATCTGCCTCTGGAATTCCAGGGCTACCTTGGCTCCCTAGGCAAGATGGATCCCAAGGGAGAGTCTACCCTCTGACT TTACTTTTTGCACAGACTAGGGCTGGGCCCTCTCAGCTACTTAGGGCTGTAAGTGCCCTCGGAGGAGCCAGCATTGGAAGGAGTAGTAAGAATTTGG AGGAGCGGGGGCTGGAGAGGTGGCCCAGTGGTTAAGAGCACTGGCTGCTTTTCCAGAGGTCCTGAGTTCAATTCCCAGCAACCACATGGTGGCTCAC AGCCATCTGTATTGAGATCTGACGCCCTCTTCTGGTGTGTCTGAAGACAGCTAGAGTGTGCTCATATACATAAAATAAATAAATCTTAAAAATAATA ATTTGGAGAAGGGCTGGCTCTGCCCCATGCTGGCTCATGGGGCCTCCCTTAGGGTACTCAGACCTCAGAGTCAGTTGACACCTGGTCCTTTATCTCT GGGCAGGACATCAGCCACCTGCTCTGCCACTAAGAGGCTAAGGAGGCGTCCACGGGAGTGAGGAACTTGGAATCAGGCCAGACGGGGGTGGTGGAAG TTTCCAGGCATGTAAGCCTCTCCTCGTAGCTCTATAGTGCGCACCTCTTCCCCAGGTCCCAGGATCTGAGAGGACTGCTCGGTCCCTTACTTGTTCC AGAATCTGGGTGGAGGCTTTTGGGAAACAACTTGGGGGCCTTTCTCAATCCACCACCCCCCCCCCTTTCCCAGGTCTCAAGAACTTTTCCAGTCTTT CCCATTTTTTGGACACTCCAGGGGGTAAGAAAAAAAAGAGGCAACAGGCAAAGCCCGGTGGTGACTTCTCTCTAACTCCCTAGGGGGAGCCAGAGTC CACTGAAGCCAGGCATACCTGACAGGACAGCTCCTACAGGGCCAGAAGTCTGAGAAGGCTTCATGGAGGAGGTGTTATTTGGAGGAAAGTAAAGGCT CTGTGAACATTCTCTAGGTCTGTGAGTGCAGAGTACTTTGCGGGTAGAAATAAAGGCGAGCAGGAGGAGGTGGGAGAGAGGAAAGGCTAAGGAAAGT AAGCTGGGGGTCGTGGGAGAGCCAAACATGAACCCAGAATCTTTGCAAAGGCCACTTCATAGAGGACATTGCATTACTGACATGGAGGGCAAAGGGG AGCCATGGAAGAATTTTAGGCAGAAAAGGGTCTGGGTCAGACTTAGTTTTAGAAAGATAAGTCAAGAGGCTGGAGAGATGGCTCAGCGGTTAAGAGC ACTGGCTACTCTTCCAGAGGTCCTGAGTTCAATTCCCAGCAACCCCACATGGGGCGACTCACAACCATCTGTAATGTGATCCAGTGCCCTCTTCTGG TGTGTCTGAAGACAGCTACAGTGTACTCATATACATAAAAAAATAAGAGAAAGATAAGTGAGGCGTGGAAGTGCTTGCCTGTAACCCTAACACTTGG GAGGCCGGGGGCAGAGGTATTGAAATTAGGGGCCTGGAGTGGGCCCAGGGAGGCCCTGTCTCAATAACAAGCGACATGGGGTTGGAGAGTGACTTTA TGGTTAAAAGCAAGCATTGACTGCGGAGCGCCCCCACTGGATAGCTCATAACTGCCCCTACCTCCAGCTGCAGCAGATCTGACGTGCTTGTCTAGAG TCCTCGAGCATCTGCGCACTGATGCACACACATTCTCTCTGTTAGACACATGACACCTATACTCACACGTGCATACACACACACACACACTCTACTC TCTCCCTCTCTCACCTATTTTTAATCTAAAAACATAACAAAACAATAACAGGCTGCACCCTAGAAGAGACACTGGATGGGGCAAGGCAGAAGGTGGA GACAGAGGTTAGGAATGGACAAGGCAGAAGACCAGAAGACCGTGGGAAGTGACATCCACAGTATTGGACATATGTCATCTGAAAGATACTGGAAGAG CAGCAAGCACCACCCCCACCCCACCCCACCCCCCTAAGATTTCCCTGCATAGCGATGGAACTTGCTCTGTAGACCAGGCTGGCCTCCAACTCCCAGA GATCCCATCTCCCGAGTGCTGGGATTGGGGAGCTTGCCACACCACTGGGCTGTCCTAAGAGCAGAGCTCCAGAGCTGGAGGACGACTTGGCTTGGGA GAGGGAGAAAAGGCCACGGGAAAAGGCTAGGAATCCAGCTGAGGCCTCTGGGGGCAACATCTATGCTCTAAATATCTTGGTGGTTCTTCTTCTTCTT CTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTTTCCTTCTTTTCCTTCTTTTCCTTCTTT TCCTTCTTTTCCTTCTTCTCCTTCTTTTCCTTCTTCTCCTTCTTCTCCTTCTTCTCCTTCTTCTCCTTCTCCTCCTTCTCCTCCTTCTCCTCCTTCT CCTTCTTCTCCTTCTTCTTCTCCTTCTTCTCCTTCTTCTCCCTCTTCTCCTTCTTCTCCTTCTCCTTCTTCTCTCCTCCTCCTCCTCCTCCTTCTGT AAGTATATATATATATATATATATATATATATACCATAGCTGTACAGATGTTTGTGAGCCTTCGTGTGGTTGATGGGAGTTGGACCTCTGCTTGCTC CAGTCAACCCTACTCACTCAGGTCATCAGCTCATCTCTGCTCACCCAGTCCCTGCTTGCTCCAGTCCAAAGATTTATTTATTATAATACATAAGTAC ACTGTAGCTGTCTTCAGACGCCAGAAGAGGGCATCAGATCTCACTACGGGTGGTTGTAAGCCACCATGTGGTTGCTGGGATTTGAACTTGAACTCAG GACCTTCAGAAGAGCAGTCAGTGCTCTTACCCACTGAGCCATTTCGCCAGTCCCTAATACCTGGGTTCTTAACCTGCAAATTAAATGGGTAACTGGC GACAGTATATATATATATATATTCATTCCAATCTTCCCTGGAGCTTACGAGATTTTTGTCATGAGTTGAGTGTCAACAAAAGTTAATGAAGAAACTG GATTTATCATTCATTATTCATAGGCTAAACTCACTCAGAGGAGTCACATTTGAGCCGTAAGCCCCCTCCCCACAATGCAAAGAGAAGGGAAGGGTCC AGCCAGCCCTCACACCCATCCAGCCCCTCGCTGCACTTCCCTGGCTTCCCCTGCCCCAGGCCAGTTTGGAT1GGCAGCAGGTGCAGGGGTGGATTTC TTCCACTCCTGACTGCTACAGAGCAGTGGGGAGACAGGAGTCTGCGTTCTGGCATGGGAATGAAAATTTACAGGAGCTTCCTCGGTAGGGTGAATTC CAAGTGAGAGGGCTGGGCCAGCCCAAACCCCTACCATCTCAGTCTCCTCTTCCTCCCAGGTATCTGGGAAGGTCCTGTAGAGTCTGAAGACTTCAGC AGTAGCTGCATCTTTGTTTATTATGCTACCTTCTGCCTCCTCAGGGAGGAGGAGCGCTGGAAGAGTACATGCTGGGTAAATTCTCAGAGGGCGCTGC AGGTGAGTGGCCTACAGGGGGTCCTGGTGTAACTTTAATTTTTTATTTTTTTAAATCTTATTTTTAATGATTTCTTTTAATGTTTTAACCCGTTTTT TTGTAACCCACCAGAGGTAGTGGAAAAGAAAGAAAACGGGAGAAATGGACCTATTTAGAAAGGTTTTTTGGAACAACAGATGTCTGTGTTATCTGGA AATCAGCAGTTCAGTTCACAGGTTAGCAGGCATCGATGGCTTGATCCACTAGCAAACACCTCACAGACACACCAGCAGGCCAGTTCAGTACAGTCGG GTTAGCAACGGTGGTGACACGACCTAGTAGAGACAGCCAGGCCTCAGCCTCAGCTTCAGTCAGCAAGAACGACACTGGGAGAAGTTCTCAACTGTGC CTCTCTCAAGGAAAGCCACGATCAGCAAAGACTCAAGACCCACAAGCGGTGTGTAGCTAGCTCTATACGCAAATCTAGCTCTGTCTCCATCACTCCG TGGCGTCCTATTTATACCCTCCAAACATCACGTGTCCTCCATATGCCTTGTCTTGCCTCAGCACAGGCATCCAATCAGCCCCAGTCCTTAGAAGCAA CAAACAAACTGCAGCACACCACAAGAGTTTTGGTGTGTTTCTCTTTATGGAGTTCCGACAAAGGCAGTTCAACTACACAGTATAAGGCAGACCAATA CATGCACGTTGTTAGCAAAAAAATCCTTCATCACGTGACTTTTCACATTCTTGCTTTAGCAGAACATCCTCTCTCCTGTGTCTGCTTCAGCGAAACG TTCCTTCCTGAGTCTGCCTTAGTTAGCCTTTCACACCTGTGTCCACTTTAACAAACTGTTCCTTCACGTGTTTGCCGAGCAAAACACCATCCGACCG ACCTTTCAAAGAACCCTTAAGTTTCCACTTCACCCGGGGATTGGGGGGGGGGCAGTGGCAGAGGAACAGGAAGGCTGGCTATTCTCTATATTGGCCC AACATTCATGAATGAGCTCAGCTAACTTCTTCTCTTCTGTGGGCCTCAGTTTCCTCATCTGAGAAATGGCAGTCTTGAGACAGGGTGGGGCCCGAGG AAAAGGACTCGGTTCTGGGGAGGAACAGCTTCAGAGTGCAGAGTTACTGTGTATTTACTGTGGGTCTCTGGGCACAGCATCAGTTTTGCCTTACACA AAATTGATGGGGGTGGTGCACGCAGTGTAGGAGTGGGGGGCACACAGTGCAGGGGCTGGGGGCACACAGTGCAGGGGTGGGGGAATGCAGTGCAGGG GTGGGGGAATGCAGTGCAGTGCTGGGGGGCATGCAGTGCAGTGCTGGGGGGCATGCAGTGCAGGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGCTGGGGGGCACGCAGTGCAGGGGTGGGGGGAATGCAGT GCTGGGGGCATGCAGTGCAGGGGTGGGGCTGTTATCTGCTGCTTTGGTGTGTGTGCACCAGTGTGGTCTGCTCCAGGAGAGGAACCGGCAGACTTCT TTCAGAGAAGCAGTGTTAGGAGATAACTGAAAGGGGAAGTGGTTATGGCGGGGTGCCTCTAAGGAGCCCCCTTTCCTGCCCAGGCCCAAGAGGTTCC TCTCAGCTCTCCCTGGCAATGTTGCTCAGGCTGCTTGCTGGGACTGAGAGTAGACAAAGGGACTGGAGAGAAGCTGGGAACTCTGGAGGGGATAAGA CTTGGGTCAAGGGGGGAGGGTATAGGGGTCTTTCGGGATAGCATTTGAAATGTAAATGAAGAAAATATCTAATAAAAAAAAAAGACTTGCTGGGCGT GGTGGCGCACACCTTTAATCCCAGCACTCGGGAGGCAGAGGCAGGCGGATTTCTGAGTTCGAGGCCAGCCTGGTCTTCAAAGTGAGTTCCAGGACAG CCAGGGATATACAGAGAAACCCCTGTCTTGAAAAAACAAAACAAAACAAAACAAAACAAAAGACTTGGGTCAAACTGATGGCTTGGAACAAAAAAGT CCCACTTCCACTGTGACTAGCTGAATGACCATAGACAAACAAACCAACAAAAATTGGCTCCTTGGTGCTGTTGGCTCTCATGGGGCCTGATAACATT CACCTCATTACTGATTGGAGGCTGCCTTGGGGTAATATCTGTAAGGGCTTCAGGCATCCTGTAGGGTGCCAAGGTGTCTTCCACTCCTTGCTGCAGG GGACTCTCATCTTCCACAGTGGGAAGACTTTTTTTTTTAAGATTAATTTATTATTACATGTAACTACACTGTAGCTGTCTTCAGACACATCAGAAGA GGGTGTCAGATCTCATTATGGGTGGTTGTGAGTCACCATGTGGTTGCTGGGATTTGAACTCAGGACCTTCAGGAGAGCAGTCAGTGCCCTTAACTGC TGATCCACCTCTCCAGCCCAGTGGAAAGACTTCTACCACTGATGGTGCAGAGCCTTATTCAAGATGGGACAACTGTGCAGTAACTGTCCCTGGTGCT GGGTTGTACAGATCCTGCAACTGAACCAATCTCAAGGGGCATTATGCTGCATCTGAGGCCACTGCCCACATGTATGGCATTGACTGGACCTCAGAAA AAGGCGTGGGTCACCCCTACTGTGGGATTACACATAATGCTTTGCTAGAGCACTCAATTGTCAGTATCGTTGTCACTTCTTACAGCTTCCATCTCTT GGCCACCTCACTGCCAACTGCCTCTGCTTCCAGGGCCACTTTGTAACACTTTACAAATCTTTTCTTACTCAGGAGAAAACCTATAGAAAACGGGGCA GGGACACAAGCTTCAGTTCCATTCAAGGAAGAACTTCTAATCAGGAAGATGAAGGGTTGAACTTCTCAGGGCTTCAGACCCTAGAAGGATACAAGAA ATGCTAGGGGGCAGTGAGGTGAGAGATTCAACCACCCACTCGCAATCCTCCTGGGCCCCCGAGCCCAAAGTGGATGCATCTGAGGACAGCTTTCTCT CACCCTTTGTTTGCTGTTTGGTTGGTTGGTTGATTTTGTGAGACAGGGTTTCACTCAGCAGGCAGCCCTGGCTGTCCTAGAAACTCTGTAGACCAGG TTGGCCTTGAACTCAGAGATTCACATGCCTCTGCCTCCTGAGTGCTGGGCTTAAAGACATGTGCCATCACCACTTGGTTCCCATTTGTTTCTTGTAA AGTGTGTTTTCTTTTTTTCTTTTTTTTTCATTTTTTATTAGGTATTTAGCTCATTTACATTTCCAATGCTATACCAAAAGTCCCTGATAGTGATGAT CAGAACATTGTCTCCCTGATTGAAGAGGACACTGGGATTGGGCTCTGCTATAAACCAGACCCCCCCATCCCGAGACCCCCAAATCTCCTGATATTAC ATCCTGAGCCTCTATGAGTGTAAAGGAGCTCGTGTCTGATCTTCCACAGACGTGACTTTTTCGCCTTTAAGGGACCTCTTTAATAGGTCCCCCACCC TCTGCCAAAGTGTGCTCTCTCCCACCATTANNNNNNNNNNNNNNNNNNNNTCCCCCTTTTTGGCCCTGGCGTTCCCCTGTACTGGGGCATATAAGGT TTGCGTGTCCAATGGGCCTCTCTTTCCAGTGATGGCCGACTAGGCCATCTTTTGATACATATGCAGCTAGAGTCAAGAGCTCCGGGGTACTGGTTAG TTCATAAGGTTGTTCCACCTATAGGGTTGCAGATCCCTTTAGCTCCTTGGATTCTTTCTCTACCTCCTCCATTGGGAGCTAAAGTGTGTTTTCTACC CAAACCTCTGTAATGGGCCACATTCTCCCTTTCTGTTGCTCGTCTATCCCATTGGTTCAAACCTAGGAAGATATATTTTTTTCCTTCCATGAGACAA GAAGGCTGTGAAACAGAGGCTTCCTACCGTTTGTTGAAAGGTCAATTTGTCCAAAGCCCCAACATATTATTTTATAAAGTTTTAGTTTTATTTCATG TGCATCTTTTGCCTGTAATTATATATGTGCACCAAGTATGTGCTGGGCGCCTATGCAGGTCAGGAGAGTGCCAGGAATCCCCTGGGCCTACAGTTAC AGATGATGGTGAGCCACCATGTGGGTGCTGGGAACCAAACCAGGGCCCTCTGAAAGAGCAGCAAGTGGTCTTTACAGCTGTGCTGTCTCTCATGCCC AAGCCCTACCATAATAAACAATTATGAAACATGGCCCTAACCTCAGAGTCTCAAAGTCTCATTTCTAAGTTCAGGGCCCTCTAAGGTTTATAGCAAC TTAGATTCATACTAGGATGTTAAAGCTTCTTGGTGAATTTGAAGCCGGGATAACCTTGTAACCCAAAAAGCGGAGACTTCTGGAGTTCCTTCAAAGG GTAGATAGGAAGTTTACCGTAGAAGTGCTTTTCAGCTCCATGGTCAAGTTTCGGGTGGACCAATAAGGTCCACAAGGTTTCACTACAAGAGAGGCTC TGAGGAAAGCGCTTGTCAACATTCTGACCCCTACCAGCAGGAACATTACATGTGCCGCCTACACAATGTTTTGCTCCCCCGTCCTTTCCCCGCCCAG TGTCCATTCATTTACCAGGTCCCAGCAGGGCGGGGCTGTCCTGTTTTCTATCCCTGGGCTGGGCACACGTCTTACGAGCGCCTGCAGTAAGCAGTCA ACAGTGTTTGGCCCGAATAGGGGCACAGGCTGTTCCGGAAGTGGACAGTGTCAGAGGTTCTAGCCGGAGAGGAGGGAGGGAGAGCCGCTGGGGAGCC TCATTGCCCCAGGGCCGAGGGTGGAGCCTTTCCCAGTCGGGAAAGGGCTGGGCCCAGCCTACATGTGAGCGCAGGACAGAGTGACTGCCAGCGCTCC CTTGAGAAGTCTGGGTGTAGCACGCTGGCGGTTGACTTCCCAGGACTCTTCTGTGACCTGTGAGCCGAGGATTACTGGGTACCCCAGATTCCCAGAA CCCAGTCCTGGATTGCAGATCTGTAAGGACCGCGAAAGATTGAGCAAAGAAGTCTTTCTGGACTTAAGAGTTCCGGAACAGGACGTCCAGCCCATCT CCGGATCCCGACTGGATCCACACCTTCAGCCTCGTGCCCTGTCCCGGGTTCCCCGCGCCCGGGGCCCCGCGCTTGAGCGCCCCCGCATGGCGGGGCC ATGTCCTAGGGCCGGGGTTCTAGAACGGGCGGGCAGCTGCTGGCAGGACCCGCTGGCGGAGGCGCTGAGCCGGGGCCGCTCGTCTCCTGCGGTCACG GGTCGGGGCTGCGCGCGGAGCCGGCCTCTCAGTGTGGTCTACGTGCTGACCCGGGAGCCGGGGCCCGGGGTGGAGCCCGGGTCGGGAACCGAGGCAG AGCCGCTGCCGTTGCGATGCCTGCGCGAAGCCTGCGCTCAGCTCCAGGGCACACGGCCACCCCCGCAGCTGCGCAGCCTACCCTTTGCGACGCTGGC GCTAGGCGACACCGCTGCGCTGGACTCCTTCTACAACGCGGCTGAGCGACTTGGGGCGGGGCTTGAGTCTAGGCGGAGCAAGGGGTGGAGCTTTAGA ACCCTGACGGGGCGGGTGTGGGTACCAGGTCTAGGGAATTTACGGTAAACTAAAGCCGAACTTGAGACAAGGCAGTAACGACAGGGCATTTAGTGGA TTATGGATGTGATGGGCTTGAGGCTGGATCTGGGGATTCAGGCCTGGCTCCGGAGTTTAAGTATCTTTCGGTGAGCGTGGTGCCAAGCAGGTGGGGC GGAGCAGGCGAACTCTAAGGGCGGGGCTGGGGAGGGACGGGGCTGAGGGAGGGGCAGAGCTGCGCTTCCCTGCGTAAGCGGGAGAACTCTTTTTCAG GATGATCTCTCGTTGGACTTTTGAGGGTGAATCAGGCCTGAGACGGAAGTTCGGTCTATGGCAAGGGGCCATCTCTGCAGGATTGGGGTTGATAAGT CCTAGCATACTACATCCCACATGGGACTAAAGGGGCGGGAAAGGAAGTACTGAGGCAACTCTTCGGGACTGGATTATAGGAGAAAGGGATTGTATTT GGAGACTAGGAGTCGAAAGAAAATGGGTGGGGCAGGGGTGGGTCTAGAGGAGACACAGGGAGTCCAAGGGTGAGGTTGGAAGATAGCTATTCCTCTC TTTCCCACCTACCGGATGCTCCACCTCATCCCTATTTGTTTATCTCCGAGTCAGAGAGCCTTGTATCCTGGACATCTGCTAAATTGTAGCTTAAAAA TGAAGGCTGACCCGGTCAGACCACAGATAAAGTGGAATCATCTGCGTTGACTCATACAGTCCCTCCCTTGCGGACATTGTCACTTAAAGATGGCTGG ATACAGTAAGCTACACAAACACACATAAAAGCACGACGTTGTCTTCACACACGATGATGCAGATCACCCTCAGGACCCTGGCTTCAAGATTGGAGAG ATGGTTCTGAGGTTAAGAGCACTTGCTGCTCGCCCAGAGGACCCGAGGTTCCCAGCATGCACACGGGGTGTGCATGCTCACAACCACCTGTAACTTT ATCTCCAGAGGATCCTGATGCCGCTTTCTATCATACACTCACACCAACACACACATACATATAAATAAACAGAGAGAGAGGAGAGAGAGAGAGACAG AGAAAGAGACAGAGAATGGGACTTCTTTTTGCAAAGTTCCTGTCTCCTACATAACCTGGAAGTGCTCAGTGGGATGAAGGTCCCTGGGCATCTCCTG TAACACCACCAATAAGAGTACTGTGAAAACCCCGGGAAGCTCTCGAGAGCAGCACCGACTTTGGCATGAGGTGCAGGCAAGGCACTTGACGTGACAT GCATCTCCAGGCTCCTTCGCCACTGAGCTGGGCTTCCACACTCAGGCCTACACTTCTGTGTCCACAGATGTAGTGGTGCTGGAGGTGAGCAGCTCCC TGGCACAGCCTTCCTTGTTCTACCACCTCGGTGTGCGTGAGAGCTTCAGCATGACCAACAACGTGCTCCTCTGTTCCCAGGCAGAGCTCCCTGATCT GCAGGCCCTTCGTGTAAGTGGCCAGGGGGCTGGGGGCTGGGAAGACAGGTGCAGGGTTGGGGTGAGGCCACCCCAGAATGCCAGTATCTGATTGTCT GCCTCCTGCAGGAGGATGTTTTCCAGAAGAACTCGGTGAGCAGAATCTACCCCTCATGCCAACGTTATAACCTCTGACCCCTACTAACCTTCCTAGC TTCCTCCTTTGTCTCTGACATCAGTGTGACCCTCAGCACCATGTAGCATCCTTTTGTGACGTGCGGCTCTTTTCTTCTATTCCTATCTTCACCAGTA CTAACCGCCAGTCCGTCTCTAACCCTGTGCTGACCTATGTGTGACCTCCACTAATTGCTGCCTTCTTCCCACCAGGATTGTGTTGGCAGCTACACAC TGATTCCTTATGTGGTGACAGCCACTGGCCGGGTCTTATGTGGCGATGCAGGCCTCCTGAGGGGCATAGCCGATGGGCTAGTACAGGCTGGGGCGGG CACTGAAGCCCTCCTCACTCCCCTGGTGGGCCGGCTTGTCCGTCTGTTGGAGGCTACACCCACAGACTCTTGGTAATGGGGCTCAGGGGGAGGCGGT ACTAGGTAGAGACTGATGAAGGTAAAGTGTGCTGGGGCTGAGGGGCAGGCTCATCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC TCTCTCTCTCTCTGGTCTCTGGGCATCAGCGGCTATTTCCGGGAGACCATTCGTCAGGATATCCGGCAGGCTCGGGAGCGATTCAGTGGGCAGCAGC TGAGGCAGGAGCTGGCTCGCCTGCAGCGGAGGCTGGACAGCGTGGAGCTGCTGAGCCCTGACATTGTCATGAATCTGCTGCTGTCGTACCGCGATGT CCAGGTGTGTGGCGTTCGGAGAGGCCATGACATAGGATATAACTCCAGCACTCAAGTGCTTGTGTCAGGAGGGGCAGGAGTCTGAGGTCATCCTGTT TACAAGCAAGTCTAAGGCCAACCTGGGCTTCAAGGAATCTTGTGTGTAAACCTAAGAAAGAGACCATTGTATGACAGACAGATACAAGTGCAGCTCC TGGCTGAGCCTCACTAGTGGCTTTAAGTAAATTGTCTGAGCCTCAATTTTCTTATTTGTTTCATCATCATTATTATTTTTTAAACATGGTCTCACTG TGCATTCCTGGCTGGCCTGGAACTCAATATGTAGACCAGGCTGGCCTACATATCCACCTGTTTCTGCCTTCTAAGCCTTGTGCCACCACACCTGGCT TTATTGTTTTTTTTTTTTAAAGATGCATTTTATTTTTTTAATTGTGTGTATATGTGTGTGTCTGAGTTAGGGTTTGTACCTTGTGTGTGCAGTTACC TGTGGAAGACAGGAGAGAGTCTTGGATCCTTTGGGACTGGAGTTAAAAGAGGTTGTGAACTTCCTGTTGTGAGTTCTGGACCCCAAACTGCAGTCTT CTGGAAGAGCAGCCTGCACTCTTAACTGCTGCTAGTTATCTCTTCAGCCCATATTTCCTTCTTTTTTGAGGGATGATGTGGTCATTGCCTCACAGGG CATTGGTGAGGTTAGAAACACCCAATGTGGGGTGCATAGTGGGTTCTCCAGGAAGGTGTGGTCTGTAAATCTGCTTGGCCCGAGGGAGGTGTGCAAA GTCTTCAGGTTGTGGGTAGTAGAAATTTCCTTCAAACTGACAGTAGTTACCCCTGTCTTAAATCCCAGCACTCAGTAAGCAGAGGCAGGCAGATATC TGAGAGTTCAAGGGTAGCCTGGTCTACAGGGTGAATTCCAGGACACCCAGGGCTATGTAGAAAAACCTCATCTCAAAAAAACAAGCAGAAAAAATGA TTTCTGCTGGCAGTGATGGTGCGGGTCTTTAGTCCCAGCACTCGGGAGGCAGTAGCAGGTGGATCTGTGAGCTTGAGGCCAGCCTGGTCTACAGAGA GAGTTCCAGGGCAGCCAGGGCTACCGATCTTTCCTCGCTGTCAAGGGCTCATCGAGATGCTGCACGCTGTCTCCCACAGGACTACTCGGCCATCATT GAGCTGGTGGAGACGCTGCAGGCTTTGCCCACCTGTGATGTGGCTGAACAGCACAATGTCTGCTTTCACTACACATTTGCCCTCAACAGGTGGGTAA TGGGGCACGGCTTGAGTCAGAGTCTTGGAAGTCTCTGTGACCTGCCAAGCAAGAGCACTGCAATCTGGAACCACTGCTCCTCGGGTATCTTGCTAAC CTGGGTCCTAATGTCACAAGGTTCCTGTTGGTCTGGGCTAAGGATGCATGGTGGGGACAGAGGACGTGGGATCCCCTTGATAGGGTCATAGCTGTCC AAGGTCGCTACTCCTTAGAGTTGTTTGCAACTAGAAATCCCTTCCATCTGGAGTCACTAACTCTAGAGATCAATGCTTCCCGGGGTTAGTGTCATTT GAGGCTCATTAATAGTAAGCCCCCAGAAGGGTCCCTTCCGTTTATGGTCTATTGGGTCCCAGGACTGGGTGGGTCAGAGCCATCAGACAGGTCTTCA GTGTATGTTCCTCCGCCTTAGGAGGAACAGGCCTGGGGACCGGGAGAAAGCCCTGGCTGTCCTGCTGCCATTGGTGAAGTATGAAGGTCCCGTGGCT CCGGATCTGTACTGCATGTGTGGTCGTATCTACAAGGACATGTTCTTCACTTCTGGCTTCCAAAATGCCGGGCACCTGGAGCAGGCCTATCACTGGT AATTCACATAAGAGTAAAGAGAGGGCTTAGCGATGGGACTGAAGGGTGGGGTTGCGGGCATCCATTCAGCCTGGCATCCCCTGCCCGACCCGACTCC AGGTACCGCAAGGCGTTTGATGTGGAGCCCAGCCTGCACTCAGGCATCAATGCAGCTGTTCTCCTCATTGCAGCCGGGCAGCATTTCGAAGACTCTG AGGAGCTCCGGCTGATTGGTGAGGCCTGCTGTTAGCCCACAGCACCCTGCACAGGCTCCAAAGGGCAAGGAAAGGGCCCCAGGCGGGAAAAAGCGCT GACTCAAAGTGGGCTTCGAGACTGATCGGTGCCTGAGGTCTGAGGTCTCAGGAGCCTTTGAGTGCCTCTCTTCCCAAGCCCACACTTCCGGTTGTCA CACTTTATCCCACATCTATTTGTGCCCTAGCTCTCCCCTGTGCTAGGCTCTTAGCGCTGAGATCTTGCCACACCTACCAGATCTACATTCATATCCA CACTCCTGTGCGTGAGGGCCACAGTGGGACCCACACTTGAGCCTTACTCACTCCGGGACCTACACTGGATTGAGCCCACGCCACCCTCCCCCAGGCA TGAAGCTGGCCTGCCTGCTAGCCCGCAAAGGCTGTGTGGAGAAGATGCAGTACTACTGGGATGTGGGATTCTACCTGGGAGCCCAGATTCTTGCCAA CGACCCCATCCAGGTGGTGCTGGCTGCAGAGCAACTGTACAAGCTTAATGCCCCCATTTGGTAGGTGGCCCCTTCTTCAGCCCTGCACCCATGCCCG TTGGCACCCCTCCCCAAGCCATGACCCCAATACTTTGATGTCACTACGATAGATAGACAGTGCCCGTGTTCCCCTCTGTTCGTGGTATGTGATGCCC GTATCCTGACTACATGCAGCTGAGTGGCACCAGCCGGCTCCTAGGCTGAGCTGAGGCCAAGGCTGTCTGTGCATTTAGGTACTTGGTCTCCGTGATG GAGACCTTCCTACTGTACCAGCATTTCAGACCCACACCAGAGCCCTCAGGAGGACCCCCGCTTCGAGCTCACTTCTGGCTCCACTTTCTGCTACAAT CCTGCCAGCCTTTCAAGATGGCTCCTCCTCAGGAGGACCAGTGCCTGGTAAGGGCAGTGGGGCCTAGGGACCCAGGGGCCCAGGGACAAGCACATTA TGACCGATCCCTTTCCCCGCTACTGCTTACAGGTACTGGTGCTGGAGATAAACAAGGTCCTGCTGCCTGCCAGGCTTGAGATTCAGGGAACAGACCC CATGAGCGCAGTGACCCTAAGCTTGCTGGAGCCAGAGACTCAGGTGAGCTCTGAGACCCATTACTCACCGATCCACCTTTCTTTCTCCTATCCTCTC TAGTCCCAGCGCCTCCACAACCTCCACCCCTTTCTTCTCACAGGAGGATCCTTCCAGCTGGACCTTCCCAGTCACCTCCATCTGTGGGATCAGGTGA GAGCTGAACCTTCCGGCAAGCTCCTGTGCCACCAAGCCTGGCATTCAGTAGCCTCTCTTCTTCCCTAGCACCTCCAAGCTGGACCAGCGCTGCTGCT TCCCTGTACGTACTTCCTCCGGCCCAGGACGTCCAGCTGTGCTTTCCCAGTGTGGAGCGCTGCCAGCGGTGCGCTCAACCTTTCTGAGTTGGGGATG GGACGCCCAGGGGACGGAACGGACCAGGTGCTCCTGGGGGATGGTTCCTGGCTGTTCCCCTTCCAGCTGTTTCCCCCTCTTCAGGTTCTGTGGCCTA ATTCACGTCTTGGTGATGAATCCGGATTCCTCCGCGCCCACTGAGGAGGCAGAAGGCGCAAGGGAAGTGCTGGAGGTGAGGCTGCAGAAATGGGGGG GTTGGAGGAGAGCGAGGGGTGAAGGGTCCCTGCTAAGCGGGTGCTCTGGGTTCCACAGTTTGATTATGAATACTCGGAGACCGGTGAGCGGCTGGTG CTGGGCAGAGGCACATATGGGGTGGTGTATGCTGGCCGAGACAGGCACACGAGGGTACGAATCGCCATCAAGGAGATCCCAGAGAGAGATAGCAGGT GGGGTGCATTGGTCGATGAAGGTCTGGGGTCTCGGGAGGGTATATGCAAACAGGGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTCTGTCTGTTGAGG AAACGTGAGAACTGACTGATTGTGGGCATGGAAAGAGCTCTTTAGTGGCTGGACTAGGGGTGGTGGCCCTTACAGTAGATAAGAGAGGTCTGTGGGC GGGGTGTTGGATCTGGGGGCATGGTTTCATGGTACAGGACCATGGGAGGTTATCTCTGCTCACATCTGCCCATTGCTCTCTCCTCGACACTCCCAGA TTCTCTCAGCCTCTGCATGAAGAGATCGCTCTTCACAAACGACTTCGTCATAAGAATATTGTGCGTTATCTGGGCTCAGCCAGCCAGGGCGGCTACC TCAAGATCTTCATGGAGGAAGTGCCTGGAGGTACCAGCCCTGCGTGGGAGGGGAGTGAAACCTGAGGTGTGGGGCGTGGGAATGGAGCCAGACCAGG GTGGCAACCCCTGAGGGGAAATGAACTCTAGCGTGCGTGGGTATCACCTAGAATTAGCTGACAGGGCTCACTGGGTGATGGAAGTCTGGGTCATGGG AATGGGTGTGTTTGGGCTTTGATCAGAGGGATGTAGGTAGAGTAAGCGGACATCAATTATAAACTTGGTTTGTCTCTGCCCAGGCAGCCTGTCCTCC TTGCTTAGGTCAGTGTGGGGACCCCTAAAGGACAATGAGAGCACTATTAGCTTCTATACACGTCAGATCCTACAAGGACTCAGCTACCTCCATGAGA ACCGCATCGTTCACAGAGACATCAAGGTCAGCCCTGTGGCTGCTCCGGGTGTGTGGAGACACAGTACCAAACTGAAGCTGACAGTAATGGTGGGAGA GAGCACACTTTGGCAGAGGGTGGGGGACCTATTAAAGAGGTCCCTTAAAGGCGAAAAAGTCACGTCTGTGGAAGATCAGACACGAGCTCCTTTACAC TCATAGAGGCTCAGGATGTAATATCAGGAGATTTGGGGGTCTCGGGATGGGGGGGTCTGGTTTATAGCAGAGCCCAATCCCAGTGTCCTCTTCAATC AGGGAGACAATGTTTTGATCAACACCTTCAGTGGGCTGCTCAAGATTTCTGACTTTGGCACCTCTAAGCGGCTGGCAGGCATCACACCGTGCACGGA GACTTTCACAGGTAATGGGGGGTGGGGGTGGGGTGAGGGTGTCAAGCTCTTGGAGACTTCTGGGGAATGGAGTTTTTTTTCTTGGCACAGAGTTACA ATTTTAAAGATTTATTTATTTATTTTATGTATATGAGTACACTGTAGCTGTATAGATGGTTGTGAGCCTTCATGTGGTTGTTGGGAATTGAATTTAG GACCTCTGCTCTCTCTAGTCGGCCCAGCTTGCTCAGTCCCTGACTGCTCTGGCCCAAAGATTTATTTATTATTATAAATAAGTACATTGTAGCTGTC TTCAGACACACCAGAAGAGGGTGTCAGATCTCATTAAGGGTGGTTGTGAGCCACCATGTGGTTGCTGGGAATTGGACTCGGGACCTTCGGAAGAGCA GTCAGTGCTCTTACCCGATGAGCCATCTCACCAGCCCTTGAATTACAGTTTTAATGGTGAATGGAAGGAATCTGGCTGGAGACAGGTGACTGGATCC AGGAACCGCTGGTAAAATCTATACTCCAAGGTTGGGTAACTAATGAGAAAGACCTCAGCATCGAAAACGGATGCAAGGCCGCGTGTGTTGGGGGTGT GAGACGGGTTGGTAGAATTTGAAGGGAGGACGATGTAGCGTCACGTACAAGCCAGAACCCTCCTGATGGTTGAACGCTATGCAGCCTAGAATGAAGG ACGGAAGCTTGGCAGGTGACGGGGCCTAGGTGTGCACATGGCCAGTGGATGATGGGGACTTGATGCCTACCTGGCATTGTTGTTCCTATTTGTGGTC TAGGGACTCTGCAGTATATGGCCCCGGAAATCATCGACCAGGGCCCGCGAGGATATGGGAAGGCAGCTGACATCTGGTCTCTGGGCTGCACTGTAAT CGAGATGGCAACAGGTCGACCGCCCTTCCATGAACTAGGGAGCCCTCAGGCTGCGATGTTTCAGGCGAGTCTCTCTGGGGTGTGGCCTACGGAGGGT GGGCGGAGCCAGATGGGGCCAGTGGGGTTATCTATCCCATCTGCCCCACCTCCGCAGGTGGGCATGTACAAGGTACATCCACCCGTGCCCGGTTCCC TGTCAGCTGAGGCCCAAGCCTTCCTCCTCCGAACTTTTGAGCCAGATCCCCGCCTCCGAGCCAGTGCCCAAGAGCTGCTGGGAGACCCCTTCCTTCA GCCAGGGAAGAGGAGCCGCAGCCCGGGCTCTCCTCGGCATACTCCCCGGCCCTCAGGTGCTATGGGGGTGGAGGGGGACAACCTAGTGAAGGGGAGA GGGGCTGATGAGGCGAAAAGACTAACAGCTTGTTCCTCCCTCAGGCGCCCCTTCCGGTCCTTCCAGTCCTTCAGCTGACTCAGCCACACAGTCTCAG ACATTCCCAAGGCCCCAGGCACCCTCTCAGCACCCACCCAGCCCCCCAAAGCGCTGCCTTAGTTATGGGGACACCAGTCAGCTCCGGTGAGCGCCTA GGGTCCTGGAGTGGGTTCTCTTCATCTTTTTTTGCCGTTGTATTAATTTCCTCCAGAAAAAAAAAGCCTCCCTGGGTCGCAAACACCCTGACCACTT CCAAGGACCGTATCTACTACCTCCTGCCCTCTCCCAGATGCCGGTGGCATTCACTCTGCCAACCCCCAGATGGGCTTAATTTCTATTATCCCCGTGA AGTAGGCATAAAAGAGCCAAGATTCAAACCCTGCAACATAGGTGGTTGGTTGCATGGTGTTGCCCACCCTCCATCTAATGCCCCTCATTGTGCCCAG TGTGCCCGAGGAGCCCGCTGCCGAGGAACCCGCGTCCCCAGAAGAGAGTTCAGGCCTGAGTCTGCTGCACCAGGAGAGCAAGCGCCGGGCCATGCTG GCTGCGGTGCTGGAACAGGAGGTGCCCACACTAGCAGAGAATCTCCTGGAACAGGAACAGGTGGGCGGCCCGCCCCAGCGCCCCCTGGTGGTCGAGC TGGGATAAGAATTTATAGTGCACCGGCGAGCATCTCTGTTGACTGCGGATGCGAACATCCACGGACGTCCCCTCTTTTTAGGACTCTCGACTCAGCA AGATTCATGTGGAACTTCTGCTTCGGTGCCTTGGGGCACAAATCCACACTCCTAACCGCCGGCAGCTGGCCCAGGAGCTGCGGACCCTGCAAGCTCA GCTGCGGGCCCAGAGCCTGGGCCCTGCGCTTTTGAAGGGGCCGCTCTTCGCCTTTCCAGACGCGGTGAGGAAGCTATCTCGAAGTTAGGGCTATGCA ATAACAGGTCGCGAGCAAGATCTTGATGTTCCAGGATTCTATGATTTCCAGGAAGACGCATGTCCAGTCCTGGCTTCCCTGTCCCACCCTTGACCCC AAGTCCGCCCACCTCTTTTAGACTGCAGCCGACTTTCTAGGGCTTTGCAACTCAAGCCCCACCTCTGTTTGAGATTCAACTGTCTCAACCGCGCCTT CCTTCCCTCCCCAGGTGAAGCAGATCCTCCGCAGACGCCAGATCCGCCCACACTGGATGTTCGTGTTGGACTCGCTGCTCAGCCGTGCAGTCCGGGC GGCGCTGGCGGTGCTGGACGCGGGTAGGTGGGGTTGGATCCCGCCGGCCGGCCGGGGCGGGGTGCGTGGCCCTGGGGGCGTGGCGAACATAAAATTG GTACTTCGCGGCCCTCCCTTCTCCCTGACCGTCTGGGGTCCTAAACGGGCGCGGCGCCCACCTGGAGCTCAGTCTACTCAAATTGGTAGAGTCGGAG AAGAAAGCGGTCTTACCGAGGTCAGAAGAGTCGAGTAAAGAGGAGTCCCAGCAGAAACCTCAGGAGAGCCAGGCGCTGCAGAGCCAGCTCCCACCAG AGCAGGGACCCCCATCGTTGATGGTGGAGTTGGGCCTTTTGCGAGCCGAGACTGACAGGTGAAGCCTTTTGGAATCACTCGGATAACCTGCAGAGGC TTCAATCTGCAGGCCCTTCCATTCTACCACCCCTACCTTCCCACAGGCTTCGGGACCTTCTGGCTGAGAAGGAACGTGAGTGCCAGGCGCTGGTGCA ACAGGCCCTGCATCGGGTGCATGCAGAGACCAGGAAGTATGCCCCAGCTTCCGAGACCCCAGGTGAGCCGACTTGACTGGGAAATGGTGAAGGTAAG GCCACAGAGGACACCTTTGCCCTCCCTCATCACCTGCCTTTTTGACAGCCACTCTCCCAAAGGACCAGAACCTGGTGCGGTGGCTACAGGAACTGAG TGTAGATCCAGCCACTATCCAAACGGTGAGTAAGTGTGAGCTGGCTCCCACCACCCACCCACCAAAGGCATCTCCTCTGTCTTCCAGCTATTCAAAC TTTGTCATTGCTGCAAAGATGCTCAATACTGAAAGAGCCCTTAGTATGCACCTCTCCTCTCATTATAGGGATGGGGAAACTCAGGCCACAAGGGGGC CGCCTGCCTGAGAGTTCTGTTAGAAGCAAGAACCCGAGTTTCTAGTTGAATTTCTGTGCAACTTGATCTTTCTCTGTTTCTGTGGTTCTCGGTTCAT AACCAGCTCCTGAGTCATAGCTTCACCCTTCAAACCCTGCTCACCTGTGCCACTCAAGATGATCTAGTCTACACCAGAATCAGGTATGTCTTGGGCC TTCCAGGGGTGAGTCATGTAGCACTTGCTAGCAATTTCAGGACATCCCCTTCCCTATGGGCCTGGCCTGCCTTTGATTCCTCCCTGAAAACCATAGT GGTTCCTAAAGAGAGAGCATGGGCTGCCTTCTGGCTGAATTACATTGATCCCTGATGTCCCCAGGGGAGGGATGGTATGCCGGATTTGGAGAGCCAT CTTGGCACAGCGAGCAGGAGCCACATCGGTCACCCCAGTACCCCGGGACGCTGAGTGATGACATCAAAGGACACAGATACGGATGGATGAACAGAGA AGACACAAACAGCTTTGGACACACCTGTCCTAGAACCCAGGAGCAACTACAGGGACCAGGCCCAACCCCAATGGGTGGAACTAACTAGGGAGGCACC CAAAGGACACTACATACAATCATAGACTATTAAACAGAACACTTGCTACCATGCTTGTCTTGGCAACTTCAGAAGGGTGTTGGGGGGAGTGAGGAGT GTCCAAGGAGAAGCCCCTTGAGGTCTCCATGTCTGAGTGACCCTTTTTCATTTCCTGGGCTTTCAAGCTAGTGCCTTACTACCCAGACTTCATACCC AGTTAAGCAGTCAGTAGCTCTGTAAACAGACTTTATTGATTCCGGCCATGGGTGTGCTTTAGGTGGGGGGTCCACAGAGGGGTTTGACAAGGCTATG CCCTGGGGACCAGGTTGGTTCTGAGGGGCAGAAGGCCATCCACCCACTCACAGGGCCGCTCCAGGAGTGTCTGCCACAGCTGCTTCTCCTCCGGTGT GGAATCCATCCAGGGCACCTGAAGCCCATAACTGCTGCCTGGATGTGGGTGAGCCAAAGTGGAAGCTACTGTTACCTTGGAGACCTCGGGTCCCAAG AGCAACTTTCTGGTCCCAGATTATGCATTGTGCCCAAGCATCCCGAACCTCCCAGCTTGGCTCCCCTCAAGGGCCTGCTCTGCTCACCTGTACCAAG GCTGAGGCGTGTGCCCCCCAGCTGGCGACTGGCCAGGGCCCCATGGTCCCACAGGGAGAGCTCGGCACAGGCTTGGCGTAGGTCAGCAGGCCCGAAG CCGTCATAAACCATGGTGTGGTTGAACACAGGGCTGAGACTTCTTCGAACCACTCTTGTGCGTTGGCGGCTGGCCCGACTGTCATCAGGCAGCACTG AGCTGCGACAGGGTAATAAAGGAGGGCTAGTCTTAGGCAATCACCCTCTGACACTCCCTCCCTGAGCCAGCCAGGCACCATGTCCTGTCCTTTCATA TGGCCGTGTTCCCTGACCGTTCCCTGGCCCTGGCCTGAGATCAGGTCTCTAGCCCTCTTACACTAATCTTTTCTTAAGGCTTCGTACGTGAAGCTAA CTGTTCACAGGATTCCAGAGAGAAGTCTCTGAAATGCAATTCTGCTATTTTCTGGCCCAGTAACCTTCAGTATTCCCTGCCCTCCCCTTTAGTTTCC AAAGCCTCAACCACTCTGTAGAGTAGAATAATATTACTCTGATATAGAGTAATAGAAAGGAAGCCAGGACGGGAGCCCCAACTCAGAGCAGTCTACT CTGTTTCACTCCTGGAGGGTGCGGTAACAACACCTGAAGCACCCAGAAACACTTTTAGAGGTTCTGTAAAAACTTACTTTGTAAACCACAGAGCTGG GGTGTAGCTTAGTGGTAGAGCCATATATGTGTGTATGTATATATATGCATGCATGCTTAGGGTGACTGAAGCATTACGGTCAGTTCGCAGCATGTTA AAAGACAACTACAATCACCAACCATTGACTCACAAGTTCAGAGCCAAGCCCCATAGCTTGTCCCTCCAAGAGTTCCAAGGAGGACCCTTGTGGCCTT TGCATCATAGTGCGTGCATAGTAGGTGCACAGCCTCTGCAGACTGCAGCCTATGCTGGCTAATGTCAACTTGACACAAACTTGAGCAGTGGTTCTCA ACCTCCCTAAGGCTGTGGTCCTTTAAGACCCCCAACCATGAAATTATTTCATTGCTTCTTTGTAACTGTAATTTTGCTACTGTTATGACTTGTACTG TAAATATCTGATGTTTGCCACCCACAGGTTGAGAACCACTGAGCTAGAGTCCTCTGAGAGGAGGGAATAAGCTAAGCAAATGCCTCCATAAGATGGG TCATGCCGTGGCCAAGCCTGTAGAGCATTTCCTTAAGTACTGATTGAGCAAGGCTAAGCAAGCCTTGGAGAGCAACCCATGAGGAGCCAGGCAGTCA GCAGCCCTCCTCTGTGGCCTCTGCATCAGCTCCTGCCTTCAGGTCCCTGCCCTGTTTGAGTTGCTGCCCTGGCTTCCTTCAGTGATGGACTACAGCG TGGAAGTGTAGAACCCTTTCCTCCCCAACCTGCTTTCTGGTCGTGGTGTTTCATCAAAATAATAGAAACCCTAACCACATAGAGCCCCTTAGTTCCC CAACTCAGATTTTGTTGTTACACAAGGTCTCACTATGTAGCTTGGGCTGACCTGGAACTAGCAATGTAGACCAGGCTGTCCTGGAACTCAGAGACAC ACCTGCCTTTGCCTCCCCAGTGCTGGGATTAAAAATGCACACCACCACCAGGCAGTGGTGACGTATGCCTTTAATCCTAGCACTCGGGAGGCAGAGG CAGGTGGATTTCTGAGTTCCAGGCCAGCCTGGTCCACAGAGTGAGTTCCAGGACAGCCAAGGCTACACAGAGAAACCCTGTCTCGAAAACAAACAAA AAAATAAAACCCAAAAACATGCCACCGGACCTAGCCTAAGCTTTTATTTTGAGACAGGGATCTTGTGTATCCCATGTAGCCTTAATGACCTTGAACT AATCCTCCTGCCTCCAATCCTAGTTTATGTAGGTTGTTAGAGATCAACCCAGAGCCTCTTGCATGCTAACCCAGCAACTCCACCAACGGATACCCAG CCCCAGCCCCCAACTCCAACCCCCTGCCTGGCTTATCACCTCTGCCCTGCTGATCTTGGCTGGGGGGACAGGTGGATCAGAGGTCAAGAGCAGAAGG GACTAACACCTTAGGCGGCCTCTCACCATTGAATGTAAGTGTCCAGGGATCCTGGTCGCAGTGGTACCAGGCTCTGAGCTTCCTTTACCCAGAAGTG TAACTCCCCACTCTGAGGCTGTCCTCCTCCTGTGGGGACACTCCAGTTCAGACTACCACCTCACAGAGTGGGTGGGTCTCCCACCTCCATGGGCCAG TCCAGCTTAAGCTCTCTCTTGGCAGTCACTTACCCTCTGAGCCGGCAGGGACATACTTAAGGGACAGAGACAGCAGTCCACGGCTGGGAAGCTCATC TGGAGATGGAGGAACCTGAAAAGGCGGGGAGTGGAGAGAAACAGGATTATGTGTGAGAAGGGTGTTGGGGACAGGGCCTCTACTGAGGAGCCCAATG GCAACGTTCCCCAGAAGAGGCGCCCTGGCTGGCAAGCCTGGCCTAATGGTATCAGTATGAGGCTAAGTGAGGCTCTGCAAACCGGTCCGTTGGGTGT TTGGTCCAGTGGGCCTGTGGGAATATCAGTGACTGCACACCAGCCCTTACCCGAGGCTGCAGGGGGAGCCAGGTAGCCTCAGAGTCCCAGTTCCACG TGTCTAGGGGCACTTCTACTTCTCCCAGAAAGATGTTGCGACCCAGACTTTCCCGGTGCCACACGGACAGGCTCAGCACGCGGCCTGGGAGATCAGC CTGCTGGACAGAGTGCTGGGGACAGGAGGTGAGTTTCAGAGGCATGCCCTGGCATCGCTGTGGCTCACCTGTTAGCTGGAGATGGTCTCCCAGGTTC CTTTCTAGGATGGGCTCCTGAGGCAGGGTTAACTGGGGTCCTAGCACAAGTTGTGGGGCTTCAGATTGCAAGACCACTAGCTGTCTTGTCATTACTC TTCTGGGGCCGTCAGGAAAATTAAGGAACCCGGCAGCCCCTGCCACTCACCCCACTGAAAATGGTACCCTGTTTATTTGCAGGGATGACAGAACCCT TGATGCCTCACCCGCAGAGTCTCGTTGAAGATCGGGTTCAGATTCCGTTTCTTCACTGACGTCTTACGCTTGCTCTGCTTATCCGGGAGGAGGTAGC TTTTCACGTAGCTGGGCAAGGGATGTGAAGGCTGGAGGTAAGGAAGAGCCCTTCCAGAGCTTTGTCCAGCTCTGGGGTCTTCTCTAGTCACCATCCA TAACACAGCGTGCCCATGTGGATGTTAATTAACAGGCATCCAATTTAAGACGCTTCCCAATCATATTGTTGTGCCCATTTTGAAGAAGAGAAAACTG AGGCCGAGGCAGTTAAGTGGTAGGCTGGGTGATGGAGCCCCGCCCCTCAGGCCCCCTGCAGCCCACCTGTGACGTAGGCACTCACGGATCGGAGCGG CGTCGCCGGGCAGCGGCCAGGCCCTGGCACTGAATCACCTGTACTCGCAGCTCAGAGGTGCCAGGCTCGTAGTGCAGCGAGAAGAGCACGGAGCCTC GCACCTGCACCGTGCCTGCCTCCTCTCCGGATAGGCTCATCAGGCTGCCGCTCAGCTGTGGGCGGGGCGGGTGGATGATCAGGGTCCCCATAGGGAA GCTTCCCACTGTGGGGTTTGCCTGGGCTTTCCCAGCTCCCAGCCCCTCCCTAGCTCTTCACCGTAGAGGAATTGAGGCTGGACACAGAGGAGCTGCT GCTGAGCATGCGGTCAAGAGAGGGGCCGAGCCCCGGGGCCTCTTCTCCATTCTCCAGGATCTTGGAGGTCGCCTTGGACTGGAGAGGGGAGAAGCGA CAGGGGCGCCCTCTTACTTCCCTGGACCTTGCAGGGGAGTTGGGGGTAAGGGGTCATTCACCGACGGTTCCCACCCCCAGGGCAGGTACACTCTCAG TCTGGAATCCGCTCCCGGTCTTGAGAACAGCCAGTGGCTACTCCCGCCTACCTGGGCTGGAGTTGGCTGGGACTCCTGCTCCGCCTTCTGCTCAGGA TCCAGCTCTGGGTCCGCCTCTGCCACCTGCACACCCCCTTCGCCAGGGGCTGGAATGGGGTACAAGTTGCTGAAAGAGCCCCTCTCCTATGTGTCCC TAAGCAAACCTGGAGGGTTCACCTGTCAGCTTCAGGCCCCAGGGGTGACCTAGAGTTGTCCCCGAAGGCCAAGTTGGGGTCCCAGGAAGAAGAGGAA GGTGGACATGATGGTTGTGGGGGCAGTCATTAAAAATGGCCTCTGATCCCCTCAACCTCTTAGGTTCCCCAGCTTACCCTCCAGCTCACATTCCTGG TCCTGGGGCTCCTCCTCCTGACCTTCGGAAGCCTTTGAGGGTACATATGGTGAGGACAAATCAGGCCCCTGAAGAAAGCAGAGGGTAGAGGTCACGG TGGGGGTTAATGAGAAAGGGATCAAGGGTTATGCTGGGGTCAGAGGTCAAAGACTCCAGCCTGCTCACCTTGCTTGGTCTGAGTTAGAGTAGGGCTG CCCTCAGGGCAGGGCTACCTACCAGCTGCAGGACCAGTCAAGCCTGTACTTCACACCCTGGCATCCCAGGCCTGTCTCTCCTGCCGGGCCTGCCTGA CTCCTAGGCTCAGCTGGTGGGGGCCCCAACATCTGAGTCCCTGGCCTCACCCGCCTCAGTCCAACCCCACCTTTGCTGGCGACACCTCGTGTGTGGT TGACAATGACCTTGGACTCCTGTTTCTACCTCCTGAGTGCCAGGATCTGAGGTGTTCACCACAATGCCGGGTTTATGTGGTGGCTGGGGACCAAACC CAGAGCGTCATGCGTGTTAAGCCAGCACTCTATCAACTGAGCTACATCCTTTGTGTTTGTTTTTCAAGGCGGCGTAGGGCGGGGTTCCCTGTGTAGC CCTGGCCTTCTGAAACTCTAGAGTTGTTAAAAATTGGAGGCTGGCCTCAAACTCACAGAGATCCACCTGTCTCTGCCTCCCAAGTGCTGGGATTAAA GGGGCAACCTGCCCCACAACCACAGCCCTGCG1GTATCCTTATTCTTTGGTTTTGTTGTTTATTTAGACTTATTTGTTTTATGTAAGTACAGACACA CCAAAAGAGAGCATCTGACCCCACTACAGATGGTTGTGAGCCACCATGTGGTTGCTGGGAATTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCTTAAGGAATAACTTGGGATT CTCCAGGTTGAGCAGCATAGTAATCACTGTTCATTAAGTGCTTATTGTGGGCCATGCCTGATAGTTTATTTTGCACATTACATGTCATGTGTGCGTG GTATGCATGCCTGTATGCTCCCATGTATGTGGTCATACGCATGTGGAGGTCAGAGTATGAACTTGCTCATCTTCAGCTCTCTCCATCCTATATACTG AGGCAAGGTCTCTCACATAAGCTCTAAGCTCAGTGCTTTGGTGAGTCTAGCTAGCCAGCTTACTCCAGCAATGCCCTAGCACCATTGCCGGAGTGCT GGGACAGTGAGTGGGCCACCTTACCCCTGGCATTTATGTGGGTGCTGGGGATATGAACTCCATTTCTCAAGCCTATGCAGCAAGTGTTTTACCCACG GAACCATCTCCCTGACCCCTTAGCTGATGTTTTAGTGGAGAAAGGGGAGGTTCAAGGTCAAAGTAACTGCCCAAGGTTACACAGCTGTTCCCAGACA CTGCTTGTCACTCTTGAGGTCCTCTGCCCTTCTGCTCCTCTGGGGAGACGAAATATCTTCGTCTTGGAAGTCAAAAGTACTCAAGGATTAGGGGACA TGCTCATGGCTATATCAGGTTTATATATATCTGGGAGCTGCCAGGAACCGATCAGGGTGACCTATGGGCACACTTAAAGGCTTTGACACTAGGTTCT AAGGGCTGAGGGAGGGTCCAGAAGGGTAGTACTAAGGACAGGCAGTATCTGTTCACCAAAGTATCCTGTCCCAAGGTGGCGGCCAGAGTAGAAAAAC CCAAAGACATGGAGGCTAGGGAGGGACCTGTCACAGGTTTGAGAGAAGTGAAGAGCTCTGAGCTAGCCAAGGTCAATGGAGACCAAAAGGTAGCACC AAGAACCACCCAGACCCAACCACCAGCATCCAAGGACCCCGAATCCCTTCCTTCTATCTGATGGCTGTCCTGTCTCACCTGACCCGCCCTTCCTCCA GCTGGCGCAGGTGGGCATCTCGTTTGAGGACATCAGAGATGGCCTCCTGTTCCTCCTCTGTCAGGAAGCTGAGGTCCAGCAACCCCTCAACTTCAGA TCCTGGTCCATGTGCCATGGGGAGGGAGGGCAGGGCCCAAAGCCTCTCCTGAGATGGGTGGCCTCTCTGGGGCATCAGCTGGGGTTGTGCCCCAGCT GGGCATATGTAGCTTCCTGTGGATAAACCAAGCGCTGATCAGTATCTCTCAAATGCACAGCACACATCCTGAAGCCAGCTGCCGGCTGTCTCCCAAG CATATACAGGAGTAATAAGGACCAATCAAAGGAAGGCCAGGTCAAGGTGAGGTGGGGCGTAAGTGATGCACTGCAAGAGATGCACATATGCGCATGC TCCTAAGGATGAATGACAGAGTATTGCAAGACAGTACACGCTGATACACATACCCACTGTTCTACACACATTCCAGATACCTAGACAAAGACAGTTA CATGCACACACATCCCCATGAAGGAACTGTGCGCACACATACATCATGAAGGGACTGTGCACACATACCCAGAGTCCTATGCCCAAGAGCTGTGCAG CACAGTAATTCTTAAACCTGCACACAGTATGCCCACTCGAGGACAAGTGTGCACTCACAAGAATAAGTCCCTGCATCTCCACAGATCTCTCTGGATT TCCTCACACACTGTCTAACCTGCTGCATACTACTAGAAACTAAGGATAGCTCACTCCCCTCAAAGCTAGTATTTTGCACACAACATAACCTGAGTCT TAATGAAATGCAAAAATATACCTGCATAAACATGTGGATGCATGCACAGCCCTCCCCACCGCTCATGTTTATCCCCTACCTAGCCTGCCTCTGCCCT TGCCTCCCTCCACCCTGCCCTGGCCCATTTGGCCTTCCTGTCTGAGGCAACCTCCTCCCCAACCCTCACCCCAACTTCCTCCCCCCACTCCCATAGC ACCCAGTTCCACTGAGGCCACCTGCCTGAGATTCCTCCCCACCAGCCCTTTCTCTAGGCGGAGCTTCTGAGCCCCTTGGGTCTGACCCCCGGGCTCC CCAACCTCCAGACTTGGCTGGAAGCCTCAGCTGGCAAAACAACTCATGCCCAGGTACCACAGCCACTCCGGAAGGAAAACATTGCCAGCCGAGAGGG GCATGTGGACATGGCAGGGGACCTGCACTCAGTAGTGGCCCTGGTCTGGGCCCGCTGGGCAGTCTCTCTCTTTCCCAGCCCCTCCTATGCCAGGCCC CCAGCTGGGGTTGAAAAGGGAGGAGGGCAGCTCAGGGGCAGGTCCTGGCTTGTGCCTGTCTCCTGCCTTGGTCTCCTCCCAGCTGAGTCAGTATCTA AGCACAGCAAGCAAGCGAGCCTCCTCTCCTACCCCACTTTCCCTCCGGGGGTTTCTGCATCTCCATCGCCATAGCCCTGGGCCCGATGCCTGCTCAC TGACAGTGACTCTTTCTCTGTACTTGAGGTGCTGGTATCAAGCTAGCTTGGGACTTTTCTATGGCGGGGTGTATGAGCATCGCCGTGTCCTGTTGTC CTGCTGCATTAGTAGACATGTCTGCAAGCCAGGGTAAAACATAGCATCTGTCCCTGAGTGCTGTGTTGCCTTATGATACTACAGAGTCTTACAGGAG TGTCGCTGCTGTGGGCAGTGACTTGCTGGGAGCCAGTGCCGTGTGGGTATGTGCATTTCTTCCTGTGTGGTCAGCCAGCCCAGGCTGGCTGGCTTGT GGTGTGTATGCTAGTACCCCGGGGGGCCACCAGATATGGGAGTGAAGGTGGAAGACATTTGGCAAAATTGCCTGGCTTTGTCTGACAGGTTGGCTTG GTCTGGGCTGTGGGCCTATACAAGGCCAGGATCTCTCTACCTCAAGTTGTATCTCTTTCAGAGGTAGATTAAGGATCAGGTGTCCCTTGCCCTGTAC TAACACTGTGGGACAGGGACCCTTTAGTGATAGAAAGTCTGTATGTGTATCTGGGCAGGCCAGAGTCATAATCTTGCTTACACCTCACCCCCACTCC GCCCAAACTCCTGAGGTACCAGAATGTGGTCAGGACACCAGGTGGCAGTGCCTGTCCCTTAGACCACTGGGTGTGTTACCTGTAAGGGTCCAGTAGG GACGACAACTTCAAAGGCGACTCCAGCTCTCCAGGAAGACAGTTCAGAGACTAGAAAGGCTGTGGGGACTAAAGCTGACTCGCCCAGCAGCTGCTGC CCCAGTCCCGAGGAGGTGGAGGAGGAGGAGACACCTCAGCAGGGCCTGGTGCAAAACCG MOUSE SEQUENCE - mRNA TCTGGGTGTAGCACGCTGGCGGTTGACTCCCAGGACTCTTCTGTGACCTGTGAGCCGAGGATTACTGGGTACCCCAGATTCCCAGAACCCAGTCCTG GATTGCAGATCTGTAAGGACCGCGAAAGATTGAGCAAAGAAGTCTTTCTGGACTTAAGAGTTCCGGAACAGGACGTCCAGCCCATCTCCGGATCCCG ACTGGATCCACACCTTCAGCCTCGTGCCCTGTCCCGGGTTCCCCGCGCCCGGGGCCCCGCGCTTGAGCGCCCCGCATGGCGGGGCCATGTCCTAGGG CCGGGGTTCTAGAACGGGCGGGCAGCTGCTGGCAGGACCCGCTGGCGGAGGCGCTGAGCCGGGGCCGCTCGTCTCCTGCGGTCACGGGTCGGGGCTG CGCGCGGAGCCGGCCTCTCAGTGTGGTCTACGTGCTGACCGGGAGCCGGGGCCCGGGGTGGAGCCCGGGTCGGGAACCGAGGCAGAGCCGCTGCCGT TGCGATGCCTGCGCGAAGCCTGCGCTCAGCTCCAGGCACACGGCCACCCCCGCACGTGCGCAGCCTACCCTTTGCGACGTGGCGCTAGGCGACACCG CGCTGGACTCCTTCTACAACGCGGATGTAGTGGTGCTGGAGGTGAGCAGCTCCCTGGCACAGCCTTCCTTGTTCTACCACCTCGGCGTGCGTGAGAG CTTCAGCATGACCAACAACGTGCTCCTCTGTTCCCAGGCAGAGCTCCCTGATCTGCAGGCCCTTCGTGAGGATGTTTTCCAGAAGAACTCGGATTGT GTTGGCAGCTACACACTGATTCCTTATGTGGTGACAGCCACTGGCCGGGTCTTATGTGGCGATGCAGGCCTCCTGAGGGGCATAGCCGATGGGCTAG TACAGGCTGGGGCGGGCACTGAAGCCCTCCTCACTCCCCTGGTGGGCCGGCTTGTCCGTCTGTTGGAGGCTACACCCACAGACTCTTGCGGCTATTT CCGGGAGACCATTCGTCAGGATATCCGGCAGGCTCGGGAGCGATTCAGTGGGCAGCAGCTGAGGCAGGAGCTGGCTCGCCTGCAGCGGAGGCTGGAC AGCGTGGAGCTGCTGAGCCCTGACATTGTCATGAATCTGCTGCTGTCGTACCGCGATGTCCAGGACTACTCGGCCATCATTGAGCTGGTGGAGACGC TGCAGCTTTTGCCCACCTGTGATGTGGCTGAACAGCACAATGTCTGCTTTCACTACACATTTGCCCTCAACAGGAGGAACAGGCCTGGGGACCGGGA GAAAGCCCTGGCTGTCCTGCTGCCATTGGTGAAGTATGAAGGTCCCGTGGCTCCGGATCTGTACTGCATGTGTGGTCGTATCTACAAGGACATGTTC TTCACTTCTGGCTTCCAAAATGCCGGGCACCTGGAGCAGGCCTATCACTGGTACCGCAAGGCGTTTGATGTGGAGCCCAGCCTGCACTCAGGCATCA ATGCAGCTGTTCTCCTCATTGCAGCCGGGCAGCATTTCGAAGACTCTGAGGAGCTCCGGCTGATTGGCATGAAGCTGGCCTGCCTGCTAGCCCGCAA AGGCTGTGTAGAGAAGATGCAGTACTACTGGGATGTGGGATTCTACCTGGGAGCCCAGATTCTTGCCAACGACCCCATCCAGGTGGTGCTGGCTGCA GAGCAACTGTACAAGCTTAATGCCCCCATTTGGTACTTGGTCTCCGTGATGGAGACCTTCCTACTGTACCAGCATTTCAGACCCACACCAGAGCCCT CAGGAGGACCCCCGCTTCGAGCTCACTTCTGGCTCCACTTTCTGCTACAATCCTGCCAGCCTTTCAAGATGGCTCCTCCTCAGGAGGACCAGTGCCT GGTACTGGTGCTGGAGATAAACAAGGTCCTGCTGCCTGCCAGGCTTGAGATTCAGGGAACAGACCCCATGAGCGCAGTGACCCTAAGCTTGCTGGAG CCAGAGACTCAGGAGGATCCTTCCAGCTGGACCTTCCCAGTCACCTCCATCTGTGGGATCAGCACCTCCAAGCTGGACCAGCGCTGCTGCTTCCTGT ACGCACTTCCTCCGGCCCAGGACGTCCAGCTGTGCTTTCCCAGTGTGGAGCGCTGCCAGCGGTTCTGTGGCCTAATTCAGGTCTTGGTGATGAATCC AGATTCCTCCGCGCCCACTGAGGAGGCAGAAGGCGCAAGGGAGGTGCTGGAGTTTGATTATGAATACTCGGAGACCGGTGAGCGGCTGGTGCTGGGC AGAGGCACATATGGGGTGGTGTATGCCGGCCGAGACAGGCACACGAGGGTACGAATCGCCATCAAGGAGATCCCAGAGAGAGATAGCAGATTCTCTC AGCCTCTGCATGAAGAGATCGCTCTTCACAAACGACTTCGTCATAAGAATATTGTGCGTTATCTGGGCTCAGCCAGCCAGGGCGGCTACCTCAAGAT CTTCATGGAGGAAGTGCCTGGAGGCAGCCTGTCCTCCTTGCTTAGGTCAGTGTGGGGACCCCTAAAGGACAATGAGAGCACTATTAGCTTCTATACA CGTCAGATCCTACAAGGACTCAGCTACCTCCATGAGAACCGCATCGTTCACAGAGACATCAAGGGAGACAATGTTTTGATCAACACCTTCAGTGGGC TGCTCAAGATTTCTGACTTTGGCACCTCTAAGCGGCTGGCAGGCATCACACCGTGCACGGAGACTTTCACAGGGACTCTGCAGTATATGGCCCCGGA AATCATCGACCAGGGCCCGCGAGGATATGGGAAGGCAGCTGACATCTGGTCTCTGGGCTGCACTGTAATCGAGATGGCAACAGGTCGACCGCCCTTC CATGAACTAGGGAGCCCTCAGGCTGCGATGTTTCAGGTGGGCATGTACAAGGTACATCCACCCGTGCCCGGTTCCCTGTCAGCTGAGGCCCAAGCCT TCCTCCTCCGAACTTTTGAGCCAGATCCCCGCCTCCGAGCCAGTGCCCAAGAGCTGCTGGGAGACCGCTTCCTTCAGCCAGGGAAGAGGAGCCGCAG CCCGGGCTCTCCTCGGCATACTCCCCGGCCCTCAGGCGCCCCTTCCGGTCCTTCCAGTCCTTCAGCTGACTCAGCCACACAGTCTCAGACATTCCCA AGGCCCCAGGCACCCTCTCAGCACCCACCCAGCCCCCCAAAGCGCTGCCTTAGTTATGGGGACACCAGTCAGCTCCGTGTGCCCGAGGAGCCCGCTG CCGAGGAACCCGCGTCCCCAGAAGAGAGTTCAGGCCTGACTCTGCTGCACCAGGAGAGCAAGCGCCGGCGCATGCTGGCTGCGGTGCTGGAACAGGA GGTGCCCACACTAGCAGAGAATCTCCTGGAACAGGAACAGGACTCTCGACTCAGCAAGATTCATGTGGAACTTCTGCTTCGTGGCCTTGGGGCACAA ATCCACACTCCTAACCGCCGGCAGCTGGCCCAGGAGCTGCGGACCCTGCAAGCTCAGCTGCGGGCCCAGAGCCTGGGCCCTGCGCTTTTGAAGGGGC CGCTCTTCGCCTTTCCAGACGCGGTGAAGCAGATCCTCCGCAGACGCCAGATCCGCCCACACTGGATGTTCGTGTTGGACTCGCTGCTCAGCCGTGC AGTCCGGGCGGCGCTGGCGGTGCTGGACGCGGAGTCGGAGAAGAAAGCGGTCTTACCGAGGTCAGAAGAGTCGAGTAAAGAGGAGTCCCAGCAGAAA CCTCAGGAGAGCCAGGCGCTGCAGAGCCAGCTCCCACCAGAGCAGGGACCCCCATCGTTGATGGTGGAGTTGGGCCTTTTGCGAGCCGAGACTGACA GGCTTCGGGACCTTCTGGCTGAGAAGGAACGTGAGTGCCAGGCGCTGGTGCAACAGGCCCTGCATCGGGTGCATGCAGAGACCAGGAAGTATGCCCC AGCTTCCGAGACCCCAGCCACTCTCCCAAAGGACCAGAACCTGGTGCGGTGGCTACAGGAACTGAGTGTAGATCCAGCCACTATCCAAACGCTCCTG AGTCATAGCTTCACCCTTCAAACCCTGCTCACCTGTGCCACTCAAGATGATCTAGTCTACACCAGAATCAGGGGAGGGATGGTATGCCGGATTTGGA GAGCCATCTTGGCACAGCGAGCAGGAGCCACATCGGTCACCCCAGTACCCCGGGACGCTGAGTGATGACATCAAAGGACACAGATACGGATGGATGA ACAGAGAAGACACAAACAGCTTTGGACACACCTGTCCTAGAACCCAGGAGCAACTACAGGGACCAGGCCCAACCCCAATGGGTGGAACTAACTAGGC AGGCACCCAAAGGACACTACATACAATCATAGACTATTAAACAGAACACTTGCTACC MOUSE SEQUENCE - CODING GCGGGGCCATGTCCTAGGGCCGGGGTTCTAGAACGGGCGGGCAGCTGCTGGCAGGACCCGCTGGCGGAGGCGCTGAGCCGGGGCCGCTCGTCTCCTG CGGTCACGGGTCGGGGCTGCGCGCGGAGCCGGCCTCTCAGTGTGGTCTACGTGCTGACCGGGAGCCGGGGCCCGGGGTGGAGCCCGGGTCGGGAACC GAGGCAGAGCCGCTGCCGTTGCGATGCCTGCGCGAAGCCTGCGCTCAGCTCCAGGCACACGGCCACCCCCGCACGTGCGCAGCCTACCCTTTGCGAC GTGGCGCTAGGCGACACCGCGCTGGACTCCTTCTACAACGCGGATGTAGTGGTGCTGGAGGTGAGCAGCTCCCTGGCACAGCCTTCCTTGTTCTACC ACCTCGGCGTGCGTGAGAGCTTCAGCATGACCAACAACGTGCTCCTCTGTTCCCAGGCAGAGCTCCCTGATCTGCAGGCCCTTCGTGAGGATGTTTT CCAGAAGAACTCGGATTGTGTTGGCAGCTACACACTGATTCCTTATGTGGTGACAGCCACTGGCCGGGTCTTATGTGGCGATGCAGGCCTCCTGAGG GGCATAGCCGATGGGCTAGTACAGGCTGGGGCGGGCACTGAAGCCCTCCTCACTCCCCTGGTGGGCCGGCTTGTCCGTCTGTTGGAGGCTACACCCA CAGACTCTTGCGGCTATTTCCGGGAGACCATTCGTCAGGATATCCGGCAGGCTCGGGAGCGATTCAGTGGGCAGCAGCTGAGGCAGGAGCTGGCTCG CCTGCAGCGGAGGCTGGACAGCGTGGAGCTGCTGAGCCCTGACATTGTCATGAATCTGCTGCTGTCGTACCGCGATGTCCAGGACTACTCGGCCATC ATTGAGCTGGTGGAGACGCTGCAGCTTTTGCCCACCTGTGATGTGGCTGAACAGCACAATGTCTGCTTTCACTACACATTTGCCCTCAACAGGAGGA ACAGGCCTGGGGACCGGGAGAAAGCCCTGGCTGTCCTGCTGCCATTGGTGAAGTATGAAGGTCCCGTGGCTCCGGATCTGTACTGCATGTGTGGTCG TATCTACAAGGACATGTTCTTCACTTCTGGCTTCCAAAATGCCGGGCACCTGGAGCAGGCCTATCACTGGTACCGCAAGGCGTTTGATGTGGAGCCC AGCCTGCACTCAGGCATCAATGCAGCTGITCTCCTCATTGCAGCCGGGCAGCATTTCGAACACTCTGAGGAGCTCCGGCTGATTGGCATGAAGCTGG CCTGCCTGCTAGCCCGCAAAGGCTGTGTAGAGAAGATGCAGTACTACTGGGATGTGGGATTCTACCTGGGAGCCCAGATTCTTGCCAACGACCCCAT CCAGGTGGTGCTGGCTGCAGAGCAACTGTACAAGCTTAATGCCCCCATTTGGTACTTGGTCTCCGTGATGGAGACCTTCCTACTGTACCAGCATTTC AGACCCACACCAGAGCCCTCAGGAGGACCCCCGCTTCGAGCTCACTTCTGGCTCCACTTTCTGCTACAATCCTGCCAGCCTTTCAAGATGGCTCCTC CTCAGGAGGACCAGTGCCTGGTACTGGTGCTGGAGATAAACAAGGTCCTGCTGCCTGCCAGGCTTGAGATTCAGGGAACAGACCCCATGAGCGCAGT GACCCTAAGCTTGCTGGAGCCAGAGACTCAGGAGGATCCTTCCAGCTGGACCTTCCCAGTCACCTCCATCTGTGGGATCAGCACCTCCAAGCTGGAC CAGCGCTGCTGCTTCCTGTACGCACTTCCTCCGGCCCAGGACGTCCAGCTGTGCTTTCCCAGTGTGGAGCGCTGCCAGCGGTTCTGTGGCCTAATTC AGGTCTTGGTGATGAATCCAGATTCCTCCGCGCCCACTGAGGAGGCAGAAGGCGCAAGGGAGGTGCTGGAGTTTGATTATGAATACTCGGAGACCGG TGAGCGGCTGGTGCTGGGCAGAGGCACATATGGGGTGGTGTATGCCGGCCGAGACAGGCACACGAGGGTACGAATCGCCATCAAGGAGATCCCAGAG AGAGATAGCAGATTCTCTCAGCCTCTGCATGAAGAGATCGCTCTTCACAAACGACTTCGTCATAAGAATATTGIGCGTTATCTGGGCTCAGCCAGCC AGGGCGGCTACCTCAAGATCTTCATGGAGGAAGTGCCTGGAGGCAGCCTGTCCTCCTTGCTTAGGTCAGTGTGGGGACCCCTAAAGGACAATGAGAG CACTATTAGCTTCTATACACGTCAGATCCTACAAGGACTCAGCTACCTCCATGAGAACCGCATCGTTCACAGAGACATCAAGGGAGACAATGTTTTG ATCAACACCTTCAGTGGGCTGCTCAAGATTTCTGACTTTGGCACCTCTAAGCGGCTGGCAGGCATCACACCGTGCACGGAGACTTTCACAGGGACTC TGCAGTATATGGCCCCGGAAATCATCGACCAGGGCCCGCGAGGATATGGGAAGGCAGCTGACATCTGGTCTCTGGGCTGCACTGTAATCGAGATGGC AACAGGTCGACCGCCCTTCCATGAACTAGGGAGCCCTCAGGCTGCGATGTTTCAGGTGGGCATGTACAAGGTACATCCACCCGTGCCCGGTTCCCTG TCAGCTGAGGCCCAAGCCTTCCTCCTCCGAACTTTTGAGCCAGATCCCCGCCTCCGAGCCAGTGCCCAAGAGCTGCTGGGAGACCCCTTCCTTCAGC CAGGGAAGAGGAGCCGCAGCCCGGGCTCTCCTCGGCATACTCCCCGGCCCTCAGGCGCCCCTTCCGGTCCTTCCAGTCCTTCAGCTGACTCAGCCAC ACAGTCTCAGACATTCCCAAGGCCCCAGGCACCCTCTCAGCACCCACCCAGCCCCCCAAAGCGCTGCCTTAGTTATGGGGACACCAGTCAGCTCCGT GTGCCCGAGGAGCCCGCTGCCGAGGAACCCGCGTCCCCAGAAGAGAGTTCAGGCCTGAGTCTGCTGCACCAGGAGAGCAAGCGCCGGCGCATGCTGG CTGCGGTGCTGGAACAGGAGGTGCCCACACTAGCAGAGAATCTCCTGGAACAGGAACAGGACTCTCGACTCAGCAAGATTCATGTGGAACTTCTGCT TCGTGGCCTTGGGGCACAAATCCACACTCCTAACCGCCGGCAGCTGGCCCAGGAGCTGCGGACCCTGCAAGCTCAGCTGCGGGCCCAGAGCCTGGGC CCTGCGCTTTTGAAGGGGCCGCTCTTCGCCTTTCCAGACGCGGTGAAGCAGATCCTCCGCAGACGCCAGATCCGCCCACACTGGATGTTCGTGTTGG ACTCGCTGCTCAGCCGTGCAGTCCGGGCGGCGCTGGCGGTGCTGGACGCGGAGTCGGAGAAGAAAGCGGTCTTACCGAGGTCAGAAGAGTCGAGTAA AGAGGAGTCCCAGCAGAAACCTCAGGAGAGCCAGGCGCTGCAGAGCCAGCTCCCACCAGAGCAGGGACCCCCATCGTTGATGGTGGAGTTGGGCCTT TTGCGAGCCGAGACTGACAGGCTTCGGGACCTTCTGGCTGAGAAGGAACGTGAGTGCCAGGCGCTGGTGCAACAGGCCCTGCATCGGGTGCATGCAG AGACCAGGAAGTATGCCCCAGCTTCCGAGACCCCAGCCACTCTCCCAAAGGACCAGAACCTGGTGCGGTGGCTACAGGAACTGAGTGTAGATCCAGC CACTATCCAAACGCTCCTGAGTCATAGCTTCACCCTTCAAACCCTGCTCACCTGTGCCACTCAAGATGATCTAGTCTACACCAGAATCAGGGGAGGG ATGGTATGCCGGATTTGGAGAGCCATCTTGGCACAGCGAGCAGGAGCCACATCGGTCACCCCAGTACCCCGGGACGCTGAGTGA HUMAN SEQUENCE - GENOMIC ACCACCAGGCAAGATGGGCCCCAAGGGTGAGCCAGGTGAGTAAGTGGGGCTGGAGGCCTCCCCGCTTTCTTTGCCTCTGTCCCTGGACTCTAGGGTG GGATCTCTGCTTGGCTGCTGTGCCTATGATGGCTCTCTCACAGGGGAATGGATGGCTGGGAGGAGTGGGAAGGATTAGGAGAAGGGCCTGGCTACCC TATGATGGCCCTCCTATTGGGGATGGAGGGCTGGGAGGAGTGGGGAGGATTAGGAGAAGGGCCTGGGTACCCTATGAAGGCCCTCCTACAGGGTTTG GAAGGCTGGGAGGAGTGGAGAGGATTAGGAGAAGGGCCTGGGTACCCTATGATGGCCCTCCTACAGGGTATGGAAGGCTGGGAGGAGTGGGAAGGAT TCGGAAAAGGGCCTGGGTACCGGCTCCACTGGTGGCTCAGCGCTGGGGTGCTGAGACATCAGAGCCAACACTCATCCCTTCCCTGGGGCAGGAGATC CAGTGAACCTGCTCCGGTGCCAGGAAGGTGAGGCAGCCCTTGCAGGAGCCAGGAACTTGGGATCACATGGTGTTGGGTGTTGGCAGACCCCCAAGTG TGGCCAAGATCCTCCCCACAGCCTCCTCAGAACCCTTCTTCAGGGACCTGAAGGAGCCAAGAGGGTCCCTAGGGTCCCACACTTGTTCCAGTGCCTG GGGGTGGGGGTCAGGGAATAACCTGGGCACCACCCCAGTCCATCTCCCCTTTCCCAGGCCCCAGAAACTGCCGGGAGCTGTTGAGCCAGGGCGCCAC CTTGAGCGGCTGGTACCATCTGTGCCTACCTGAGGGCAGGGCCCTCCCAGTCTTTTGTGACATGGACACCGAGGGGGGCGGCTGGCTGGTGAGTGTC TGAGAAATGGGCTAACAGGCCAGGCCCACTGGTCACTTCTCCCCCTTGGCCCCTAGGGGAGCCAGAACCCACCAGAGCAAGGCATTTCCTAGAGGAA TTCACTGACAAATGTTTAGTGAGCCCCCAATGGGACCTGAAGAAGTATGAGGGCTTCACAGAGGAGGTGCCATTTGAAAAGACCTTAAGTTGAGTGC AGTAGCTCACGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAAGAGAATTGCCTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGTTCTTGCC ATTGCACTCCAGCCTGGGTGAAAAGAGTGAAACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAATAGGGTAGGGAGGGGCATTCCAGCTAGAAG TAAAGATAAACTCAGGGAGGCAGCAGAGTAAAAGGTTTGCAGGGAACGCGTGAGTGAGCTGAGAGCAGGCGTGGGTGTCGGCTAAAGTCTGCCGGCA CTGACGGAACATGGATTGAGGACCTCTGTAAAGGCCAGTTCATGGAAGGCACTAAATGATCAACTTAAGAAGTGTGCAGCGCGCCCAGACGCGGTGG TTGGCTGGACGTGGTGGCTCACGCCTATGATCCCAGCACTTTGGGAGGCCAAGGCGGGCAGATCACCTGAGGTCAAGAGTTCGAGATCAGCCTGGCC AACATGGTGAAACCCCATCTTTACTAAAAATATAAAAATTAGCCAGGCGTGATGGTGGGCGCCTGTAATCCAAGTTATTCAGGAGGCTGAGCTGGGA GAATTGCTTGAACCCCGGAGGTGGTGGTTGCAGTGAGCCAAGATTGAGTCACTGCACTCCAGCCTGGGCAACGGAGTGAGACTCTGTCTTAAAAAAA AAAAAAAAAAAGAAGAGTGTGCAGGGCAATGGGTAGCCCCAGGAGAGTTTTAAGCAGGGGAGGGGCCAAGTAGAACTTCTGTTTTAAAAAGATGATT CGGGCTACACCATGAAAGATGCACTGCATTGGGGGACCAGTGGAGGCAGGGACATGGTTTAGGAAGACAGCAAGGAGCCAGGCAGTAAAGACAGTGG AGCAGGCCTGACACAGTAGCTCACACCTGTAATCCCAGCACCTTTTGGGAGGCCGAGGTGGGTGGATTGCCTGAGCTCAGGAGTTCAAGACCAGCCT GGGCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGCAGGTGCCTGTAATCCCAGCTATGCAGAAAGCTAAGG CACGAGAATTGCTTGNNNNNNNNNNNNNNNNNNNNAGCCGAGATCACACCACTGTACTCCAGCCTGGTAACAGGGGGTGAGACTCTATCTCAAAAAA ATAAATAAATAAAATAAGACAGTGGAGCAATGGAAATAGAAGTACTTAGGTTGACAACTCTATAGGACCTCGGGCCTACTTGGCTTGGAGGGGGAGG TGGAAGACATCAGGGTAAGGCCAGGGGTCCAGCTTGGGCTGTGGGAGTGGCCTCTCTAATGTAAAATATCTTGGTTTTTTTGTTTGTTTGTTTGTTT TGAGACGGAGTCTTGCTCTGCTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCAGTTCTTGTGC CTCAGCCTCCTGAGTAGCTGGAACTACAGGTGTGAGCCACCACACCCGGCTAATATTTGTATTTTTAGTAGAGACGGGATTTCACCATGTTGGCCAG GCTGGTTTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGAATTACAGGCATGAGCCACCAAGCGTGGCCAAATATCT TGGTTCTTATAGTAAATGAAATTGGGTTATTTTGACTGACACCCAGCAGCGCTGGCCATCTCCTGTGGGTGGGGACAGTGTTTTGTCAATTCAGTCT TCCCAGGGCTTGCAAGGCTGTGGCATGAAGTTGAGTGTCAGTAAAAGTTAACAAGGGAATGTAGAGTTCATAGAAATATTCAAAGCTAACTTGAAGG ATCCCCATTTTATCAACAGGCCCCAATCCAAAGAGAGAGTGGGTATCCACCCACCCCTCACAGTTCCTGCACCCTCAGCTGCCAGTGCCCAGCCTGG AGTAATAGCTGCTGTGCCCCCCCTCCCCCAGGTGTTTCAGAGGCGCCAGGATGGTTCTGTGGATTTCTTCCGCTCTTCCTCCTCCTACAGAGCAGGT TTTGGGAACCAAGAGTCTGAATTCTGGCTGGGAAATGAGAATTTGCACCAGCTTACTCTCCAGGGTGAGTTCCCAGCAGGGTCCTGGAGTCTGGGGG TTACTGTCTGCCATCCTGAATCCCTGCCCCACCCCCAAGAACTGAGGATTCCTCCATCCCTGCCTCCCCTTCTTTCCAGGTAACTGGGAGCTGCGGG TAGAGCTGGAAGACTTTAATGGTAACCGTACTTTCGCCCACTATGCGACCTTCCGCCTCCTCGGTGAGGTAGACCACTACCAGCTGGCACTGGGCAA GTTCTCAGAGGGCACTGCAGGTGAGTGAGCCTAAGGGGAGCAGAGGAAGGAGGCTGGATCCTTTCCCAGTGCTGCCACTGCCCCCATGAATGACCCA GGGCAATCCTGTCTCCTCTGTGGGCCTTAGTTTCCGCATCTGAGAAATGGCAATCATGAAACAGGATGGTGCAACAGTGAAGAATTTGGGATCTGGA GGCAAACAGACCTGAGTTTGAATCCATCTCTGCCATTTAGTACTTATGTGACCTTGGGCAAGTCCTACCCCTCCACTGAGCCTCAGTTTCCTCCTCT ATAAAATGGGCAGGGAGGCCGGGCACGGTGGCTCATGCCTGTAACCCTAGCACTCTGGGAGGCCGAGGCGGGCAGATAACTTGAGGTCAGGAGTTCA AACCCAACCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCCGGGCGTGGTGGAGGGTGCCTGTAATCCCAGCTACTCG GGAGGCTGAGGCAGGAGAATCACTTAAATCTGGGAGGCAGAGGTTGCAGCGAGCCAAGAGAGTGTCACTGCACTCTAGCCTGGGCGACAGAGCGAGA CTCCATCTCAGAAAAAAAAAAAAGGCGGGGGGAGCGCAGGGAGGCAAGGAGGAAGTTTTGGGTGCCGCCTGAGGCTCTGTTGAGTGTTAGTGTTCTC TGCTTTGGAAGAGGAACCACGGAAGTCTTCTTTCAGAGAAACAGTGACTATTGGGGAGAGATTTAAAAGAGGGAAGTGGTTATGAGGGAGTGCCTCA GGGAACCACCTTTCCTGGCCAGGCACCTAAGAGGTTCCTCCCAGCTTTTCCTAGCAGAGTTGCTCAGACTGGATGGGAGCTGAGAGAAGACAAAGGA GCTAGAGGGGGGCCGGGGATTCTGGAGGGGGTAAGACAGGGGGAAAAGCTGGGAGCTTTGGAGCCAGACAGTCCCGAGTTCAAGTCCTGCCGCTGCT TCAACCAGCCGAGTAACCCTGCGCAAACAACCTGGCCCCTTGGTGTTGCTCGTGGGGCCTGATAAAATTCAACTCTTAGTTGCTCTGAGACTCCCAT GGCATTATATCTCCAAAGGTGCCAGGCATGGTGCTGGGCACCAAGGTGCTTTCCATCCCTTCCCTGCTAGGGGATTCCCTGAGCCTCCACAGTGGGA GGCCCTTTACCACCTATGACGCTGACCACGATTCAAGCAACAGCAACTGTGCAGTGATTGTCCACGGTGCCTGGTGGTATGCATCCTGTTACCGATC AAATCTCAATGGTCGCTATGCAGTGTCTGAGGCTGCCGCCCACAAATATGGCATTGACTGGGCCTCAGGCCGTGGTGTGGGCCACCCCTACCGCAGG GTTCGGATGATGCTTCGATAGGGCACTCTGGCAGCCAGTGCCCTTATCTCTCCTGTACAGCTTCCGGATCGTCAGCCACCTTGCCTTTGCCAACCAC CTCTGCTTGCCTGTCCACATTTAAAAATAAAATCATTTTAGCCCTTTCAAGACTCTTCCAGTTACTGGGAAAAAACCCTAGAGGGCAGAGCAGGGAC ACAAGTTTCAGCTCCATTCAGGGAAGAATTTCCTTCCAGTCAGGAAGATGGAAAGGACAGCCTCTAAAGTAGTGAGGCTTCTGTCTCTGGAGGTGTG CAAGACAAGGCCAGAGGGGCATATAGTGGAAGGACTGGAGGAGATTCAAGCATCCATTGACAATTTCCTGAGGCTCTCTGGGTCCTGCAAGTGGATG GCTTTGTGGCAGGAATTGCACAATTGCACAGCTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTTGAGACGCAGTCTCGCTCTGTCGCCCAGGCTGGA GTGCAGTGGCACCATCCTGGCTCACTGCAAGCTCTGCCTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGAACTACAGGCACC CGTTACCACGCCCGGCGAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCATCATGTTAGCCAGGATGGTCTCAATCTCCTGACCTCATGATCTGCC CTCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGCCCGGCCGCTTTTTTTTTTTTTTTTTTTTTGAAATGGAGTCTTGCTCTGT CGCCCTGCCCAGGCTGGAGTGCAATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNCCCCGCAGCTGCGCAGCCTGCCCTTCGGGACGCTGGAGCTAGGCGACACCGCGGCTCTGGATGCCTTCTACAACGCGGGTGAGAGCGCTGGG GGCGGGGCCGGATCCGGGCGGGACTCAGGGTCCTGGGAGGGGACCAAGCCGGGCTCGAAGGCTCAAGGGAGGGGCCGAGAGGGGTACCGGGTCTAGG GGACTTAAAGTGAGCTAAAGCTGAAGGGCTTGGGACAGGGCCCGTGAAAAAAGTGGGATTTAGGGGATCTGGGGCGCGGCCGGGCTCGGGACGAGAC AGGGATCCGGGCGCGGCTCTAGGGCTCGAGGTTGGGGCTTAGGCACCCTTCAGTCGGAGCGGTGCCCAGCCAGCGGGGCAAGGATGGGGAGGGGCTT TGGAACTCTGGGGCGGGGCGGGGAGCGGCGCGGGGCTGTGGTGTCTCAGGGGTGGGGTTGGAGAACTCAGCCTCACCCTCAGGAGAATGTCACGCGG ATCTCTTGAGGACAATTACTGGGAGAGGAGCTTGGACTTAGGGAAAGGGGCCGGGAGGCTGGAGTTCAGGAGTCCTAGCATACTATTTCCAAGGATC GGGCTAGGAGAGGCAAAAAGAGAAGCGAAGGGGCCCGACGGGACTGGATACTGGGTGAGGGAGCTTAGGTTAAGTGGCCTCAGCGGCCCAGAAAGAA TGGGCGGGGAAGGGGCGGCGAAGTGGGCGGGAAAGGATGGCTCAGGGGCGGGGCCAGAAGGAGGCTATTCCCCCGCGAGTCACTCCTCCCTCCAGCC AGCCCGGATGCTCGGCCCCCATACTTACTTGCTTATGCTAGAGTCCAGTAGCTGTGCTTCCTGGATGTCCATGAAATCGTAGCCTAAAATGAAGGCT GACCCGACCACTCGGACACAAAGATACAATTATCGACAGACACAAATCGCATACATGTTGACTCATGCAGGCCCTAGCAGACGCTGTCACACACACA GATACAGTCAGACATAGTAAGCTATACATGTCACAGATATACACATACATACATTTAGGCACAGCGTTGTCTATGCACACTGATGGTAGCCCCTTTC AAGAGCCTGTGCTGAAGACCAAAGGGAGGGGACTTCTATGTTTGCGCAACTCCCACCTCCTAAATGGCCCGTAACAGACTCAACTGGTCCACAGCCT CCCTTCCCCCATGCCAGGTGCTCACAGGCTCTGAACCGTGGCCTGAGGGTCCCAACCCAGTGAGCCCAACTCCTCTCCTGCAACACTACAGAGATCA GTTCTGTGAAAGTGCCAGGGGAACCCTAAAAAGGGCCGACTGAAGCCCAAAGCAGAACCAGACCCTACTGGAGTCCCACAGCAAGGCAGGTCAAGCC AGGATGGACCCCGGCTCCTTCCCCATCAAGCTGGGCTTCAGGGATCAGCGCCACCCCCTCTGTGCCTGCAGATGTGGTGGTGCTGGAGGTGAGCAGC TCGCTGGTACAGCCCTCCCTGTTCTACCACCTTGGTGTGCGTGAGAGCTTCAGCATGACCAACAATGTGCTCCTCTGCTCCCAGGCCGACCTCCCTG ACCTGCAGGCCCTGCGGGTAGGTGGCCTGGGGCTGGTGGAGGCAGGCACAGGGCTGGGGTAAGGCCTACACAGAACACCAGTATCTGACTGTCTGCC TCCTGCAGGAGGATGTTTTCCAGAAGAACTCGGTGAGCAGAATCCACCTCTCACTCAAAAGTGCCCTTTGACTTCCGCTATGACCTCTGACCTCCAC TAATCCCCCTGGCCTCCTCAGTCACCTAACCCCCCACTGACATCCCAAGTATTCCTCTGTTTCCTGTTGCCTCCTCTCATGACGGGTGCCCCTTTCC TGCGATTCCAATTCCCACTGATGCTGACCTTTGATGCTCTCACTCCCCTTGTCTAGCCCTGTGCTGACCTCTGACCTCACTGATTCCTGCCTCCCTC CCACCAGGATTGCGTTGGCAGCTACACACTGATCCCCTATGTGGTGACGGCCACTGGTCGGGTGCTGTGTGGTGATGCAGGCCTTCTGCGGGGCCTG GCTGATGGGCTGGTACAGGCTGGAGTGGGGACCGAGGCCCTGCTCACTCCCCTGGTGGGCCGGCTTGCCCGCCTGCTGGAGGCCACACCCACAGACT CTTGGTAATGAAGGCCCCCAGGGAGGGTGCTCCAGGAGGGGGCTGGTGAGGGTACGGTGGGCTGGGGCTGAGGTACAGGCCCCACCATTCTCTCTCC CTGCCTCCCCTACCCTGGGCATCAGTGGCTATTTCCGGGAGACCATTCGGCGGGACATCCGGCAGGCGCGGGAGCGGTTCAGTGGGCCACAGCTGCG GCAGGAGCTGGCTCGCCTGCAGCGGAGACTGGACAGCGTGGAGCTGCTGAGCCCCGACATCATCATGAACTTGCTGCTCTCCTACCGCGATGTGCAG GTGCGTGGTGTTCAGAGAGGCAGTAGGGCAGCTGGCATTTGAGGTCAGGCAAACCCAAGTTCAGTTCCTGGCTGGGCCACTTGCTCACTGGTGGCTT TGGGCAAATTATCAAATGTCTCTGAGTGTTGGCCTCCTTATTTGTTAGAGAGGATGAGCATGTCGCTGCCTCCTGGGGCAGTTGTGGGGTTGGGAAC GCCCAGCATGGGGCATACAGTAGGTTCTCCCTGTGAGGTGTGTCCGCTGGGCCTGAGGGAGGCGTGCAGAAGATGGTGGCTGGGTGGGATGTCAGGA GTGGGACAGGACCCTGGCTCAAGGTTCCTTGGGGCCTGGAGGCCCATGATGCCAGTGCTTGCCGTTCCCTGATGCAGGACTACTCGGCCATCATTGA GCTGGTGGAGACGCTGCAGGCCTTGCCCACCTGTGATGTGGCCGAGCAGCATAATGTCTGCTTCCACTACACTTTTGCCCTCAACCGGTGAGTGGCA GAGCAAGGGTTAGGTCATAGCCACATAAAGGTTTCCGAAACCTAGGTCTCTGCGTGCAAAGCCATTGCTGTCTGGGATCACTGCTGTTCGGGGAATT TGCTGACCGGGGTCACTGATGTCAATAGGTCCCTGTTGTTCTGAGTTACTGCTGCCTGGGTCGGGGTGGGGGAGGTGGTGCTGCCTGTGGTATGGTC ACCGCTGTCCAAGATCACTGCTCCTAAGAGTCATCGCATCTAGGAATCACTTCCATCTGAGGTCACTAGAGAGGTCAGTGCTGGCCAGGGTCATTAT CATTTTGAGGTCATTATTGTCAGGCCCCTGGAAGGGTCCCTGCTGGTTCAGTGTCTAGAGGTCCCTGGACAGAGTAGGCCAGGGCCATCAGGGAGGG CCTGAGCCCATCTTTTCCCTAGGAGGAACAGGCCTGGGGACCGGGCGAAGGCCCTGTCTGTGCTGCTGCCGCTGGTACAGCTTGAGGGCTCTGTGGC GCCCGATCTGTACTGCATGTGTGGCCGTATCTACAAGGACATGTTCTTCAGCTCGGGTTTCCAGGATGCTGGGCACCGGGAGCAGGCCTATCACTGG TAAAGAGCACAGTGAGTGGCCGGTGGGCTAAGCTGTGAGATGAGGGGTGGTGCTGTGGGCATCAGTCCAGCCCTGTGCCCCCTACCCCCACCCCAGG TATCGCAAGGCTTTTGACGTAGAGCCCAGCCTTCACTCAGGCATCAATGCAGCTGTGCTCCTCATTGCTGCCGGGCAGCACTTTGAGGATTCCAAAG AGCTCCGGCTAATAGGTGAGCACAGATCCTGGCTCTTGTCTCGTCACCCACAGGGGTTCCGAGGGGCCTGGGAAGAGGGCAGGGAGAGAGCACACTG GGCAAGAGCTAGGATGAGCTCATCCATTTTGGACTGTCCTGCCCATACCCACACCTGGGTCCTCATACCTGTTCTGGGCCCTCAGGAGCCCTCAAAC CCACAAATGTTCCCAAACTCACATCTGCGTGTCCATTACATCCTGAATTCCACATATACCTGTGCCTGAGCTCCTGTTCCCACCCGAGATCTTGCCA TACTCAATGCCATACTCATATCTATGTTCATGTCCACACTCGGGCCCACAGAAATGGTGGGCCTCACTCACCCCTGCACCCACACTCACTGGAGCCC ATGCCTCTCTCCCCCAGGCATGAAGCTGGGCTGCCTGCTGGCCCGCAAAGGCTGCGTGGAGAAGATGCAGTATTACTGGGATGTGGGTTTCTACCTG GGAGCCCAGATCCTCGCCAATGACCCCACCCAGGTGGTGCTGGCTGCAGAGCAGCTGTATAAGCTCAATGCCCCCATATGGTAGGTGGCCCCCTCTG CATTCTTGGCCTGACCTGGGCTGTCAGCTCCTGCACCTATGTCCATTGGCATGCTAGACTGAACCCTGAGCCAATGACCTGGCTGCTTTTAGACCAG TGCCCGTGGCACCCCATGCCAACGTTCTAGCTATATCCAGGCCAGTTTCCTCTCCCTGGCAGTGCTGGTTGGTGCCTGGGCTGAACTGAGGATGTGG CTTTGCATGCAGGTACCTGGTGTCCGTGATGGAGACCTTCCTGCTCTACCAGCACTTCAGGCCCACGCCAGAGCCCCCTGGAGGGCCACCACGCCGT GCCCACTTCTGGCTCCACTTCTTGCTACAGTCCTGCCAACCATTCAAGACAGCCTGTGCCCAGGGCGACCAGTGCTTGGTGAGGCCTGTAGGGGTGG TGGACCCGGGAAAGGGGTAAGCCCCTTCTGACTGACCCCACTCCCCAACTGCCTGCAGGTGCTGGTCCTGGAGATGAACAAGGTGCTGCTGCCTGCA AAGCTCGAGGTTCGGGGTACTGACCCAGTAAGCACAGTGACCCTGAGCCTGCTGGAGCCTGAGACCCAGGTGAAGTCGCTGCTGAGGCCCCTCACTC ACCTTTGCTAGGACCTTTTCTGTGGAGCCTTTCTCCCATCCTCAGACCCCTCTCCTGTCACCAGCACTCCCCATCACACCCCATTTCTTCTTGCAGG ACATTCCCTCCAGCTGGACCTTCCCAGTCGCCTCCATATGCGGAGTCAGGTGATAGGCGGGACCTGGGGTGACTGGAAAGACGGGAGGTGAGGGTCG CTGCCACCCAGCCTGACGCTTACTGGGTTCTTCATCCCTTCCCAGCGCCTCAAAGCGCGACGAGCGCTGCTGCTTCCTCTATGCACTCCCCCCGGCT CAGGACGTCCAGCTGTGCTTCCCCAGCGTAGGGCACTGCCAGTGGTGCGCAGCCTTTCATGGTCGGGGTACTCTGAGGGCCAGGATGCCCGGGGGGG AGTGGGGGAAAGAAAGGGACGACGTCCGTTGGATGCTCCGGCTTAGGTGGGGACCAAGATGCCCCTCCCGCGGGTCTGACCTCCCCCACCTTCAGGT TCTGCGGCCTGATCCAGGCCTGGGTGACGAACCCGGATTCCACGGCGCCCGCGGAGGAGGCGGAGGGCGCGGGGGAGATGTTGGAGGTGAGGACGCG GGACTGGGAGCTCGCGGAGGGCGAGGGGCCGCGGGCCCTGCTGAACTCCCATCTCACCCCGCGCCCGGCAGTTTGATTATGAGTACACGGAGACGGG CGAGCGGCTGGTGCTGGGCAAGGGCACGTATGGGGTGGTGTACGCGGGCCGCGATCGCCACACGAGGGTCCGCATCGCCATCAAGGAGATCCCGGAG CGGGACAGCAGGTGCGGTGCGTGGCAGCGCGGGTGGGGCTGAGGGCTCGCGAGGGCCGAGTGAGCCGGGCCACGAGCGGAGCGGCTCCTGTGGGCGG GGCCTAGTGGGCGGGCTCGTAGGACCTGAGAGTTCGAGCCCTGTGGACTGGGCCCGTGGGCGGAACAGCCAGGACCGTGCGGGCGGGATTGAGGTCT GGAGGGTCCTGTGGGCAGGGTAGTAAGGGTGGGGAAGGTCGGAGAGGGCTTGTGGGCGGGGCGGGTCCTTGGGGCGGGGCCAGGCTGGCGTGGGATG GGCGGGGCTTCTCTGCCCACCTCGGTCCCTTTCCTCTCTCCCTTACCTCCCCTCAGGTTCTCTCAGCCCCTGCATGAAGAGATCGCTCTTCACAGAC GCCTGCGCCACAAGAACATAGTGCGCTATCTGGGCTCAGCTAGCCAGGGCGGCTACCTTAAGATCTTCATGGAGGAAGTGCCTGGAGGTACCTGCCC TGTGTGGGATGGGAATGAAACCGAGGTGTGAAGCATGGGACCGAGGCAGGCAGGGGTAGAGAGCCCTAGGGGGAAATGCACCCTAGTGCGTGTGGGT GGTGTAGCCTAGAATTAGCTGAGGAGTGGCGCTGGGTGATGGAGTTGGGCTACAACATGGGTGTGTCTGGGCCTTGAGCAGAGAGATGTGGGCTGGA GCCAGTGGGTGGGAAGAATGAACTTGGACTGTCCCCACCCAGGCAGCCTGTCCTCCTTGCTGCGGTCGGTGTGGGGACCCCTGAAGGACAACGAGAG CACCATCAGTTTCTACACCCGCCAGATCCTGCAGGGACTTGGCTACTTGCACGACAACCACATCGTGCACAGGGACATAAAAGTAAGCCCTGGGGCT GGCCCGCCCTCATCTGCTGAGGGTGGCGGGGAAGGAAACATGGTCCCAGACGCAGGCTGGCAGTTTAGATTAAGTGAGCAGACCTGTTGCAAAGGGT AGGGAATTCATCAGGGAGGCTCCTTAGAGAAGGAGGGGAAAGGTTCAGCTCTGAAGCCAAACCAATTGTCAGCTCCCAGAGGGGCATATAAGTGGGA TGGCAAGGGGAGAGTGTTGACAGAGGCAGGACCAGGCTGGGATCTCCAGGAGATGGGATCCCAGAAAGAGGGTCTAGTTCTGCTGGCAGGGGCCCAG ACCAGTGTCCACTAATGGCTGTCAATCAGGGGGACAATGTGCTGATCAACACCTTCAGTGGGCTGCTCAAGATTTCTGACTTCGGCACCTCCAAGCG GCTGGCAGGCATCACACCTTGCACTGAGACCTTCACAGGTAACAAGGTGTGGGGGTGGTGAGTGGGGATGCTGACCTGGGGCAGAAGATCTCTTGGA ACTTTCCAGGGAAGGGGGTTTCTCCTAGGCATGGAGTTAGAGTCCTAATGGGGAATGAAACCCAGGGTGAGTGATTGGGCCAGGGCTGAGGTGGTGG CATCTGGAACTGGAGCTTGGAGAAGTGATGAAATTGACTTTAGCACTTGAGGAGTGTTGATGCAGGCCAAGGTGGGAGTTGGAGGAAAAAGCAGGTG ATGGAGTTCAGGGGGACGAGGCAATCCAGGATGTGTGCTGGAGCACTACTGTGGGTGATGGAGTCTGTGAATGTGGTGGAGCCCAGGATGAATGACG GAAGCCTTGGCAGGCGATGGAGCCCAGGGTGGTGATGGAACTCAGGATAGATGTTTGATGACCAGGATAGGTGTTGAGGTATATTTTGGATGATAGG TTCAGTATGGGTGCAGTCGGCCTGAGGATGACGGCATTCCCCTCCCTGCTCCAACCCCATGATGAAGCCTAGATGGGCATTGGTGCTCCTGTTTCTG TCCTAGGAACTCTGCAGTATATGGCCCCAGAAATCATTGACCAGGGCCCACGCGGGTATGGGAAAGCAGCTGACATCTGGTCACTGGGCTGCACTGT CATTGAGATGGCCACAGGTCGCCCCCCCTTCCACGAGCTCGGGAGCCCACAGGCTGCCATGTTTCAGGTGAGACCTCTTTGGGCCTGGCCCATGGAA GTGGCATAGGGCCAGCCTGGGCCTTGGACACCTCTGAATGTCACCCTTGTTCACCCTCCCCCCACAGGTGGGTATGTACAAGGTCCATCCGCCAATG CCCAGCTCTCTGTCGGCCGAGGCCCAAGCCTTTCTCCTCCGAACTTTTGAGCCAGACCCCCGCCTCCGAGCCAGCGCCCAGACACTGCTGGGGGACC CCTTCCTGCAGCCTGGGAAAAGGAGCCGCAGCCCCAGCTCCCCACGACATGCTCCACGGCCCTCAGGTGCTTGCGGGTGGCGGGATGGGCACAGTGG AGGGCAGAGGAGTTGTGGAGCTGTGAGGGTGGAGGAGAGCCCAGCTGATGGCTCTGTCCCTCCCTCAGATGCCCCTTCTGCCAGTCCCACTCCTTCA GCCAACTCAACCACCCAGTCTCAGACATTCCCGTGCCCTCAGGCACCCTCTCAGCACCCACCCAGCCCCCCGAAGCGCTGCCTCAGTTATGGGGGCA CCAGCCAGCTCCGGTGAGACCAAGGCTCCTGGGATGGGTTCCTTTTGCCTGGTTTTGCCTTTTTCTCCTCTCCTACAAAAGCCCTCCCTGGGGACCT GGGCACCTTGACCACTTGTGAATGTGGCATTTGGTGCCTCCCCATGCCCTGTTCTGGCAACTCTAACTTGGACTTGTTGTGTCCTCTCAGTGCGGGG TTTATCTATGTTCATGCCTGTGAGGTAGGCATAAAAGTAGGAGAGCCAGGATTCAAACCCGGCAACAGAGGTGACTGGCCGGTTGCTGCCCGTCCTC AATCAGCAGCTCGCCCTTGTGCCCAGGGTGCCCGAGGAGCCTGCGGCCGAGGAGCCTGCGTCTCCGGAGGAGAGTTCGGGGCTGAGCCTGCTGCACC AGGAGAGCAAGCGTCGGGCCATGCTGGCCGCAGTATTGGAGCAGGAGCTGCCAGCGCTGGCGGAGAATCTGCACCAGGAGCAGAAGCAAGAGCAGGT GGGCGGCCCACTCTAGCGCCCCCTGGTGGTCGCAAAGGGTCAGGACACCTGTTGATGTCCCCGCCCCCTACCTCCGCGGCAGCGTCTCTTTTGGCTG GAGCACTCGCTGACAACCCCTCTCTTCCTTCTCAGGGGGCCCGTCTGGGCAGAAACCATGTGGAAGAGCTGCTGCGCTGCCTCGGGGCACACATCCA CACTCCCAACCGCCGGCAGCTCGCCCAGGAGCTGCGGGCGCTGCAAGGACGGCTGAGGGCCCAGGGCCTTGGGCCTGCGCTTCTGCACAGACCGCTG TTTGCCTTCCCGGATGCGGTGAGGGCGCCTTCTGGTAGTTAGAGCTGCCCAACAACAGGTAGTGAGTTCCCCGTGCCTGGTGAGGTGCCAGGACTTG ACGTTCCCAGATTCCCTGTCTCCTCTGTGAAGATCAGGCCTGCAGCAAAAAACCGTCTGCCCAGTCCTAGCTTCCCAGGCCTTCCCTGGACCTCAAG CCCTGCCCACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCTGCCTCTAGTTGAGGCTCAGCTGTCTCAGCGGCGCCTCCCTCCCCCTGCAGGTG AAGCAGATCCTCCGCAAGCGCCAGATCCGTCCACACTGGGATGTTCGTTCTGGACTCACTGCTCAGCCGTGCTGTGCGGGCAGCCCTGGGTGTGCTA GGACCGGGTAGGAGGGGAATGCCACGGGCCTCCTGCCAGCGAGGGTGTGGTGCTTGCTGGGCGCGGTGAACATCGAATGGGGCCGGTGGGGGCCAGG CGGGACAGGGGCAGGCAGGCGCCGGTGGGGGCGTGACTAAATGGACATCTCCCATACCGGCACCGCCTGGGGCCTGCCCAGAGCCGGGCACCCTACC CCCCGCACTTTGGGGTCTGGGGTTCCCAAACGGGCGTTGTAGCCTTGCCTGAGTTCACCGCACTGGGCTGCAGAGGTGGAGAAGGACGCGGTCTCAC CGAGGTCAGAGGAGCTGAGTAATGAAGGGGACTCCCAGCAGAGCCCAGGCCAGCAGAGCCCGCTTCCGGTGGAGCCCGAGCAGGGCCCCGCTCCTCT GATGGTGCAGCTGAGCCTCTTGAGGGCAGAGACTGATCGGTAAAGCCCCTTGGAATCGCTCATAGCCTCTGCCGGGCTTCAACCCACTCACCACTCA CCGCTCCATTCTACTCTTCTGCGCCCCACAGGCTGCGCGAAATCCTGGCGGGGAAGGAACGGGAGTACCAGGCCCTGGTGCAGCGGGCTCTACAGCG GCTGAATGAGGAAGCCCGGACCTATGTCCTGGCCCCAGAGCCTCCAAGTGAGTGGGCCTTGGCTGGAGAACATTATTGGTGGGTTCAAGGCAGCTTC TAGCACAAGGCACCCTTGGGCTCATCACCTGACTTGGGCTCATCACCTGAGCGGGCCTTGGCGGGAGAACATTATTGGTGGGTTCGAGGCAGCTTCT AGCACAAGGCACCCTTGGGCTCATCACCTGACTTGGGCTCATCACCTGAGTGGGCCTTGGCTGGAGAACACTATTGGTGGGTTCGAGGCAGCTTCTA GCAGGAGGCACTCTTGGGCTCATCACCTGACTGCTTCTTGACAGCTGCTCTTTCAACGGACCAGGGCCTGGTGCAGTGGCTACAGGAACTGAATGTG GATTCAGGCACCATCCAAATGGTGAGTCGGGGAGTGCTTGGCTATCCCTGACCTCACCAGCCAAAGCCTCCATCTCTGTCCATCTTCCTGCTCTTCT ACTGTGCCCTCTGATGCAGAGAATCTCACTACCAGAAGAACACTTAGTATTCTCGTCCCATTGTATGGATGACAAAACTGAGGCCCAGAAGGGTGTG ATCTGCCTCATTATTTTGGCAACAGAGCAGAGCTAGTACCTGGGTCTCGACACATCTTTCTGTAATTTCTTATTTCCCTCTTTCTGCGGGTCTTTGA CCACATCCAGCTGTTGAACCATAGCTTCACCCTCCACACTCTGCTCACCTATGCCACTCGAGATGACCTCATCTACACCCGCATCAGGTACATCCTG GGCCCCCCAAGTGTGAACCATGCATATGGCCTCATCCTGGCCAACTGCAGGCCTGCCTAGGTTCCTTCCTGGAAACCAAAGGGGCACCTGGGTCCCC TAGGGACAGAGGGGGCACTGGGCAGACAGTGTGTGCAAGATAGAGTCCAGGGCCACCTTCTGGCTGAGCCACACTGAGTCCATTACCCCCAGGGGAG GGATGGTATGCCGCATCTGGAGGGCCATCTTGGCACAGCGAGCAGGATCCACACCAGTCACCTCTGGACCCTGAGAGCTGAATGAGGGCATCATAGG CCAGACAGGCCCCAAGGATGGATGAATGGAGAGGACAAAGGCAGCTTCTGACACACCAGCCCCAGGACCTGGGGCGACTGGAGGAAGCCAGGCGAGT GGGGCCCAGGACTGGTTCCAGTGAGAGAAACCAACCACAGGCACCCAAGCACTACCAGACAAAGCGTATTAAACAGAACACTTTTGAACCTTTGTCC TGGCAATTTTGGAGGTGTATGGTGGGAGGGGTATCCTGGGAAGAGCCCCCTAGGTCTTTTTTAAAAAATTTTTTTTGGCCGGGCATGGTGGTGGCTC ATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCACGAGGTCAGGAGATCAAGACTATCCTGGCTAACATGCTGAAACCCTGTCTCT ACTAAAAATACAAAAAAATTAGCTGGGTGTGCTGGCGGGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGCGAG GCGGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTTTGTCTCAAAAAAAATAAATAAATAAATGAAAAA AAAATGTTTTTAGGCCGGGTGCGGTGGCTCATGCCTGTAATCCCCGCACTTTGGGAGGCCGAGGTGGGTGGATCATGAGGTCAGGAGTTCGAGAAGA GCCTGACCAACATGGTGAAACCTCGTCTCTACTAAAAATGCAAAAATTAGCTAGGCGTGGTGGTGCGTGCCTATAATCCCAGCTACTCAGGTGGCTG AGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCGAGATCGCGCCATTGCACTCCAGAGCGAGACTCCGTCTCAAAAAAAAAAA AAAAAAAAACCTTTTTTAGAGACAAGGTCTTACTCTGTCATCCAGGCTGGAGTGCAGTGGCATAGTCATATTCACTGCAGCCTCAAGCTTCTGGATT CAAGCGATCCTTCCTCCTCAGCCTCCTGAGTAGCTGGGACCACAGCTGTGCACCACCCACACCCACCTAATTTTTAAACTTTTTTTTTTGTAGAAAT AGCATCTCGCTTTGTGGCATAGCTCACTGCAGCCTTGAACTCCTGGGCACAAGCAATCTGCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCA TGTGACACCACCACCTGCAGCTAATTTTTAAAATTTTGTCGAGATGGGGTCTCATTATGTTGCTCAGACTGGTCTTGAACTCTTGGGCTAAAGCAAT CCTTCTGCCTCAGCCTCCCAAAGCATTGGGATTACAGGCGTGAACCACTGTGCCTGGTTTCTACTGAAGTCTTTGTGGCAGAGTCTGAAGTTCCTTA ATCTGGCCCCTCTTACTTCCCTGGCTCTTTCCTACAATCACCTTTCTTCCTCCCTGCCCCAGCAGACACCACCCTTTTATTGCTCTTAGAATAGACT TTATTGACTTTAGCCAAGGGCAGGCCCTGAGATGGGGGTCCAGAGAGAGAGGCTTGGTGGGGCTACGTCCTGGGGGCCAGGTTGGTTCTGAGGGGTA GAAGGCCATCCACCCACTCGCACGGCTGCTCCAGGAGGGCTTGCCACAGCTGCTTCTCCTCAGGTGTGGAATCCATCCAGGGCACCTGCAGCCCATA GCTGCTGCCTGGATGTGGGTGGGCAGGGGTTGAGGGCATGATCACACTGGACACCTTGGGGCCCCCAAACACCTGCCTGGTCCCAGATTATGCACTG TCCCCCGTTACCACCCTCAGTTCTCAGTAGATATCAAAGCTCAGGAAAGGACAGAGAGGTATCCAGGGCCACACACTGAGCCCCCATCTCCCAGGGC CTGTCCCAGGGCCTGTCTCAGGGTGCTGTCCCACTTACCGGTGCCCAGGCTGAGGCGTGTGCCCCCCAGCTGGCGGTTGGCCAGGGCCCCATGGTCC CAGAGGGAGAGCTCGGCACAAGCCTGGCGCAGGTCAGCAGGCCCAAAGCCATCGTACACCATGGTGTGATTGAACACAGGGCTGAGGCTGCGTCGCA CAACCCTTGTACGCTGGCGGCTGGCCCGGCTGTCATCAGGCAGCACGAAGCTGTGCGGGAGGTGGCCTGGCATCAGGTGACCCCCCTCACACTCCCT AGAGTCATCCAGTCACCACGTCCCACTCATTCTCCCTCACATATGTCCATGTCCCCTGGCTCCTGCCTGCCTGGCCTTAGACCCTCACTGCCCTGGG ACCTTTGCACCAGCCTCCTCTCAGGTCTCCTGGCTTTAAAAGTTACAGCTCCTGGCCGGGCGAGGTTGCTCACGCCTGTAATCCCAGCACTTTGGGA GGCCGAGGTGGGTGGATCACCTGAGGTCAGAAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGG GCATGGTGGCATGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGTTGGAGCCCAGGAGACTGCGGCTGCAGTGAGCTGAAATCA CACCACTGCACTCCAGCCTAGGCAACAGAGTGAGACTGCATCTTAAAAAAATTAATAATAGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACT TTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCATCCTGGTTAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATT AGCTGGGCGTGGTAGCGGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGCACCA AGATGGGGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGANNNNNNNNNNNNNNNNNNNNAATAATAATGTTACAACTCCTATTCACAGGGACTGC AGAGCAATGTCTCTGAAATGCAGTTCTGCTATTCTCGCTGGCTCAGTGACTTTTATTATCTCCCTGTTGCTCCACCACCACCCCTCCTCAAGCAGTT TCCAAGGTTTTTTTTTATTTTTTGAGATCGAGTCTCGCTCTGTTTTGCCCAGGTTGGAGTGCAGTGGCGTGATCTTGGTTCACTGCAACCTTCTGGG TTCGAGTGATTCTCCCGCCTCAGTCTCTCAAGTAGCTGGGATTACAGGCACCCACCACCACGCCCGGATAATTTCTTGTACTTTTGATAGAGATGGG GTTTCACCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCTTAAAGTGCTGGGATTACAGGCATAAGCCAC CGTGCCTGGCCTGTTTCCAAGGTTTTCAAAGCCTGGGAACCCCCTCTGCAAAATACAGTGTTGCTCAGAAGTACAGTACCTCTGTACTGCAGCCTCT GGCTGCATCAGAGTGGACACCCAGAAGTGACCCGCCCACCTCCATTTCACTCTCTAACAGTGGGGGCAGCACCTGGAGGCACCCCTAGAAGTCCCCT AGAAGCTTACACTGAACTATAAGTTCCCAGCCAAGCCCCACAGCCTGGCCTCCCAGGTTCTCTATGGAAGGACCCTTGCAGCCCTCAGCCTCAGCTT TTCAACAAGTCCTATAGGCGCCAGTCACGCTGAAATGCAGCTCCTCAAAGGTGTCCTCAACTTCCCTGACTCCAGGCCTTTGCTCAAACCGTCCCCT TCACCCCTGCTCAGTGGTGAAAGCCCAGGCTGCGTGATCAAAGGTTGATTAGTAAGGGTTTGTGGAGGTTGGGCACTCCACTGCAGGCAAAAGAATG GGAAGCCCGGAGGGCCAGCACTCCTCACCATTGTACGTAAGTGTCCAGGGATCCTGCCCGCAGCGGCAGGAGGTCCCGAGCCTCCTTCACCCAGAAG TGCAGCTCCCCGCTCGGGGGCAGTCCTGCGCCTGCGGAGAGGCTCGGCTCAGGCCCGCACACGGATGGAGTCCACCGCCCCCAAACCCGGGGACTGG AGTCTCCCGCTTTTCAGGGCGTGTCCAGCTTGGCCTCTCCGGCTGTCACTCACCCTCGGAGCCGGCGGGGACGTACTTGAGGGACAGGGCGAGTAAC CCGCGGCTCGGAAGGTCGTCGGGAGAGGGTGGGACCTGCGAGAGGCGGGCTTATCGTGGAGCAGGGGCTAATGGAAAGGGGCCTCAGGAGGGTGGGG TCTGCAGACCCGGATGGGGTGCGGCTAGAAGAGACGGCGGGGCCTGCAGGGGCAGAACCTAGGGGTCCTAGCGCCCTCGGGGAAGGGGCCGTGGCCG GCCGGGCTTCGCCTGGGGCCATGAGGTTAAGAGGTTGAGGGGAGGTTCTGTCGAAGGCGGGGTGTGAGGGGGCTGCGGGAGAGCCTGGTGGGGTAAA TGCAGGAGACCCGGGCCGCAGGTCTCCCCACGCGGCCTGGCTGCCTCACCCGGGGCTGCAGGGGGAGCCAGGTGGGCTCAGAGCCCCAGTCCCACGT GTCCAGGGGCACTTCAACTTCGCCCAGAAAGATGTTGCGACCCAGGCTTTCGCGGTGCCACACAGACAGGCTCAGCACGCGGCCCTGAAGCTCGGCC TGCGGGACGGAGTACTGAGGACAGGAGGTGAGCTTTAGTGGAGCACTGCTGGTGGCCCGCGTAGATGCTGCGCGAGTTGGCTGAGGCAGGTCCTACC GCGTTCCTACCATGATGGAATTCTGGGGAGCCCCTAAGGGCATTAATGGGGACCTGCACTATCACCACGCCCACCACGAGGCTGACAACACTGGATA ACGAGTTAATGGGCCCCCTCCGCCGATCCTCCGGGCAATGACGTTACTGGCTGCCCTTGCCACCTAGCCCCGCAGGAAGGGGGCGTCCAGTTCATTA ACGGGGAACCGCATCGTGGTCACAGCCTCACCCGGAGAGTCTCGTTGAAAACCGGATTCAGATTCCGTTTCTTCACCGCCGTCTTGCGCTTGCTCTG CTTATCCGGGAGGAGGTAGCTTTTGACGTAGCTGGGGAGGTGAGAACCCGAGGTGAGGAGGGGCCCTCCCAGAGCCTTCTCCCCTGCCTGTGGGCTC CCCCAGCCACCATCCCGAACACGTGCCAGGCCTCGTGCTAAGCGCTTTACAGGGATTGTCTCGCTTAATCGCACGCCTCCCAATAACGCTGTTGTTC CCATTTTGAAGATGAGGACGAGGAGGCCGAGACCCTGTGAATGGTGGGCTGGGCTGTGACAGCCGCGCCCCGCTTGGCCGGCGGGGCACTCACGGGT CCGAGCGGCGGCGCCGGGCGGCGGCCAGGCCCTGGCACTGGATCACGTGCACGCGCAGCTCGGCGGCGCCCGGCTCGTAGTGCAGCGCGAAGTGCAC GGAGCCGCGGACCTGCACCGCCTCCGCGTCGCCTGACAGGCTCATCTGGCTGCCGCTCAGCTGCGGACGGGAGTGGGTGGGAGTCAGGGCCGCTCGC AGGGCTCACGTCGGGGCCGCGGGCAGCGCGGAGGCTTCAGACCCGGGTCATAGGTGGCAGGCTGGGGGGCTGCAGCGGTGGGTCCCGCGGCGAGGGA GGGGCAGGCAGGGGCTACGCATCGGAACGGGTCCACCCCCCGGCCGCCCGGGTCCCCTCCCTCCCGCCTCACCGTGGAGGAGTTAAGGCTGGACACC GAGGAGCTGCTGCTGAGCATGCGGTCGAGAGAGGGGTCGGGCCCCGGGGCCTCCTCCCCATTCTCCAGGATCTGGGACGCGGCCTTGGTCTGCAGAG GGGGCAAGTGACGGGGCGCCCCTTCTTTCCCCACCCCTGCCCCGAGCGCCCTGGGTCGCGGGCGGCTCGCAGCCCTGGGCAGGAGCGCTCCCCGCCC GGAGTCCGCTCCGGATGTTGAGAGCAGCCACGGGCCACTCCCGCCTACCTGGGCTTGCTGGGGCCGCGGCTCCTGCTCTCCCCCCGACGCGGGCTCC AGCTCCGGGTCAGCCTCCTCGGCACAGACCTGTTGGTCTCCTTGGCCAGGATCTGGGGTGGGGCACGAGATGCTAAGCGAGCCCTCTCCTGCCCTCC CCTAAGCAAATTTGTAGGAACTGGTTTACAACCCCAGCGAGCTGCAGATTCAGGCCCCGGTGCTGCCCTGGGATCGTCCCCACCTCCGACGCGGGGT GGGAGTGGGGGTGACGAGGGTGAACACAGGTGGTTGGGGCCCCTTAGAGCTGCCTCTGACCCGCGAAACCTCTCCGTGCTCCCCAACAGGCGCTCCC ACTCACCTTCCTGGGCCTGGCACGCCTCCTCAGGATCTGAAGCCTTTAGGGGGACAGAAGGCGATGGGAAATCAGGTCCCTGAAGGAAGAAAGGGGT AGAGGTCACAGTACGGGGGCTGGTGAGGAAGAGGTCAAAGGTCATATTGGGGTCAGAGGTCATAGGGCTCCAGCCAGCTACCCCAGTTTCAGGTTTA GGGCAGCCCTCCGGGCAGGGCTGGCAGCCAGCTGCAGGAGCGGTGAGACCAGTGCTTCACAGCCCACCCCGCAGGGCTTGTGCCGCCTGACTCCCTA CTCCCATTGGTGGGGTCATTCGTACCTGAGTCCTCCACCTCCGCCAGGCCAGGCCAGTCCCATTCCTTTCTCACTCCTTTTTTTATTTTTATTTTTT ATATTGACCCATTGGTAGACAACCTTTTTTGCTTTTTTTTAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCAAGCGATTCTCCTGCCTCAGCCTCCCAGTAGCTGAGATTCCAGGTTATGCA CCATCATGCCCAGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTAGTCAGGCTGGTCTTGAGCTCCTGACCTCAGGTGATCTCGGCT TCCCAAAGTGCTGGGATTATAGGCGTGAGCTGCCACGACCGGCCTTTTTTTTTTATTTATTTTTTATAGACATGGGGGGCATTTTGCTATGTTGCCC AGGCTGGTCTTGAACTCCTCGGCTCAAGCGATCCTCCCACATCAGCCTCCCAAAATGCTGGGATTACAGGCATGAGCCACCGTGCCTGGCCCCACTT CACCCCTTAATAGCCAGATTCAGAAGTTCCCTTAGAGGCTGGGTCCATATACCACTCACTGTTCACCACCGTTCACCACTGTTTACCACCATTCACC ACCGTTCCCCACCGTTCACCACTGTTCCACCCAGGAGGTGATGAGGTGCAGACACAGGAAGGAACATTTCCAGGGTCTCCCCATTCCCAGGCTGGGG CTCTTTCCCCCCTGCCCCCTGCACATTCCACCTCCCCTCCAGGGACACTGTACTCACATGTTGGCTCATTCACTTACCTCAGTCTCCCTGAGCCTCT CCTGAGGGGCCTCATCAATGGTGAGCCTAGGAGTAGGGAGAGGACGCTCTCAGAGGGAGGGACCCTGGTGACTGGTGGGCACCATCTCCCCCTTCCT GAGACTCCTCCTCACCTGGGCTCTGGCCCCTCTTCCTTCTCTTTCACAGCAGCCTCAGCCTCCCTGTCGTGGCCTGGAGCCTGGTCTCCTGGGCGCA GGTGAGAAGTTCTGTGAGCCCCCATGCTCAGGAAGCCTGGCTGTGACTCGGGAGAGGCCCTGGGAGATACCCACCCACCCCATGCCCACGGAGGGGC ATTGCCCACTGAAAGACACACAGTACTGGGGGCAGCCAGGACTGGAGCCCTAGTGGTCCTCTCTCCCTGTCCACATACAGCCAGCGCCCTGGACGGC ACATGGCTTGCCCTGCCCCGAGGATCTCCTCTCACCCCTGGTGCTCTTCTTCCTGCGCATAGACGCTCGGACAAGGTCAGAGCCGAAGTGGGCATTG TGGTGCCGCTGGGAGCGTGCTTCCTGGAACCAGTCCCCTGTCAGGATCTTCAGCTGCCCAGGGTCTGCCACTGAGGCCCGGAGCTTGCTGGAGGAAG GGGGAGGGTGTGGCTGTCATGACTCACCCAAGCAACATTCCCGCCACCTACATTGTTAACAGGCTTGGGACCAGGGGCCAGGGACCCAACAGCAAAT CAGACTTGATCTGTGCTGTGGAGGAGCTCGGGCTGCTGGGGAGACCAAGTCCAGAAGAGACAAGTACACTGTAGTGAGGTGGATGATGTGATAGAAG TAAGAAGAGCCAGCTCTGCCTGTGAGAATCCAGGAGGGCTTCCCAGAGGAGGTGACATTTGAATTGCCTTTATTTATTTATTTACTTAATTATTTTG AGATGGAGTCTCCCTGCTATGCCCAGGCTGGAGTGCTGTGGCGCAATCTCAGCTCACTGCAACCTTCACCTTCCAGGCTCAAGTGATCCTCCCACCT CAGCCTCCTGTGTAGCTGGGACTACAGGCGTGTGCCACCATGCCCAGCTAATTTTTTATATATTTTTTTGTAGAGACGGGGCTTTTCCATGTTGCCC AGGCTGGTCTCTAACTCCTGGACTCAAGCAATCCACCTGCCTCAGCCTCCCACAATGTTGTAAGTCACTGTGCCCAGCCTTGAATTTCTTCTTAAAA GACAAATTGGAACTCTCCAGGTAGAGAAGGATAATAATTATTATACTTTTAATTTTATTATTTTTTTTTGAGACAGGGTCTTGCTCTGTTGCCCGGG CTGGAGTGCAGTGGCATGATCATGGCTCATTGCAGCCTGACCTCCTGGGTTCAAGCAATCCTCTCACCTCAGCTGCCTAAATAGCTGGGACTACAGG CGCACACCACCACGCCAGGCTAATTTTTTATATTTTGTAGGAATGGGGTCTCACTGTGTTGTCCAGGCTGGTCTTGAATTCCTGGGCTCAAGCAATC CTCCCGTCTCAGCCTCTCAAAGTGCTAGGATTACAGGCGTTGCCACTATCTCTGGCCAATTCCTCTTAAATCAGTGAAGTAGGACTCCTTAGCCCCA TTTTACAGACGACGAGCATGGTGCTCAAGGAGGTCAGGTGAGTTGCCAAGGCTACGTAGCTAGGAAGTGTCTGTCCCCAAACATTGCTTGTAACGCC CATGCTCTTCTACAACTGTGCTCTTCCAGGAAGAAGTACCAGCATAGGCATAGAAGTGAAGAGTGGGTTCAGGGACTGGGGAGCACCTGAGTGGCTG GAGGGGTCACTTTGTGTCTGTGTGTCGGGTCGGAGTTATGGTGAAAGAGGAGATGGTGGGGGCTGGCAAGGACCGACCAGGGAGGCCCAGTGGACCA TGCCTAGGAGCTTGCCCTTGATACTGGGGAGCCAGGGGAAGTTTTCAGCGGGGATATTAAGGACGGATCTGGCCAGGCACGGTGGCTCGCGTCTGTA ATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCATCTGAGATCAGAGGTTCAAGACCAGCTTGGCCAACATGGCGAAAACCCATCTCTACTAAAA ATACAAAAATTAGCTGGGCATGGTGGCATGTGCCTATAATCCCAGCTATTTGGGAGGCTGTGGCAGGAGAATCGCTTGAACCCGGAGGGGTGGAGGT TGCAGTGAGCCAAGATTGTGCCACTTCACTCCAGCCTGGGCGAAAAAATGAAACTCTGTCTCAAGAAAAAAAAAAAAAAGCAGACAGATCTGGGGAG CACCAGCTGCAGGAGGTGGGCCCAAGAGGCAAGCCTGGAGGCAGGGAGGCTGGCGAGAAAGCTGGTGCAGTCACCCCTGGAGAAGTGATGAGCTGTG AGCTGGCCAAGGCCAGAGGAGACTGAAGGGCAAAACCAAGAACCACGCAGACATCTGACAGGCAGTGGTGTCGGTAGGGAGCAGGATGGGGGCCACT CAAGCCTCTTGGTGCTCCCCGGCCAGGGTCTGCCCTGCCTTACCTGACCCGCCCCTCCTCCAGCTGGCGCAGGCGGGCATCTCGTTGGAGGACGCCA GCAATGGCCTCCTGCTCCTCCTCTGTCAGGAAGCTGAGGTCCAACAGTCCTTCAGTCTCAGGCTTTGGCCCATGCGCCATGGGGAGGGAGGGCAGAG CCCAAAGCCCCTCTTGCGATGGGTGGCCCCTCTGGGGCATCAGCTGGGGGGCTGTGCCCCAGCTGGGCACACGGAGCTTCCTGGGGGCAGACCGAGG GTCAG HUMAN SEQUENCE - mRNA GAATTCGAGGATCCGGGTACCATGGGGCTGGAGTGGGGACCGAGGCCCTGCTCACTCCCCTGGTGGGCCGGCTTGCCCGCCTGCTGGAGGCCACACC CACAGACTCTTGTGGCTATTTCCGGGAGACCATTCGGCGGGACATCCGGCAGGCGCGGGAGCGGTTCAGTGGGCCACAGCTGCGGCAGGAGCTGGCT CGCCTGCAGCGGAGACTGGACAGCGTGGAGCTGCTGAGCCCCGACATCATCATGAACTTGCTGCTCTCCTACCGCGATGTGCAGGACTACTCGGCCA TCATTGAGCTGGTGGAGACGCTGCAGGCCTTGCCCACCTGTGATGTGGCCGAGCAGCATAATGTCTGCTTCCACTACACTTTTGCCCTCAACCGGAG GAACAGGCCTGGGGACCGGGCGAAGGCCCTGTCTGTGCTGCTGCCGCTGGTACAGCTTGAGGGCTCTGTGGCGCCCGATCTGTACTGCATGTGTGGC CGTATCTACAAGGACATGTTCTTCAGCTCGGGTTTCCAGGATGCTGGGCACCGGGAGCAGGCCTATCACTGGTATCGCAAGGCTTTTGACGTAGAGC CCAGCCTTCACTCAGGCATCAATGCAGCTGTGCTCCTCATTGCTGCCGGGCAGCACTTTGAGGATTCCAAAGAGCTCCGGCTAATAGGCATGAAGCT GGGCTGCCTGCTGGCCCGCAAAGGCTGCGTGGAGAAGATGCAGTATTACTGGGATGTGGGTTTCTACCTGGGAGCCCAGATCCTCGCCAATGACCCC ACCCAGGTGGTGCTGGCTGCAGAGCAGCTGTATAAGCTCAATGCCCCCATATGGTACCTGGTGTCCGTGATGGAGACCTTCCTGCTCTACCAGCACT TCAGGCCCACGCCAGAGCCCCCTGGAGGGCCACCACGCCGTGCCCACTTCTGGCTCCACTTCTTGCTACAGTCCTGCCAACCATTCAAGACAGCCTG TGCCCAGGGCGACCAGTGCTTGGTGCTGGTCCTGGAGATGAACAAGGTGCTGCTGCCTGCAAAGCTCGAGGTTCGGGGTACTGACCCAGTAAGCACA GTGACCCTGAGCCTGCTGGAGCCTGAGACCCAGGACATTCCCTCCAGCTGGACCTTCCCAGTCGCCTCCATATGCGGAGTCAGCGCCTCAAAGCGCG ACGAGCGCTGCTGCTTCCTCTATGCACTCCCCCCGGCTCAGGACGTCCAGCTGTGCTTCCCCAGCGTAGGGCACTGCCAGTGGTTCTGCGGCCTGAT CCAGGCCTGGGTGACGAACCCGGATTCCACGGCGCCCGCGGAGGAGGCGGAGGGCGCGGGGGAGATGTTGGAGTTTGATTATGAGTACACGGAGACG GGCGAGCGGCTGGTGCTGGGCAAGGGCACGTATGGGGTGGTGTACGCGGGCCGCGATCGCCACACGAGGGTGCGCATCGCCATCAAGGAGATCCCGG AGCGGGACAGCAGGTTCTCTCAGCCCCTGCATGAAGAGATCGCTCTTCACAGACGCCTGCGCCACAAGAACATAGTGCGCTATCTGGGCTCAGCTAG CCACGGCGGCTACCTTAAGATCTTCATGGAGGAAGTGCCTGGAGGCAGCCTGTCCTCCTTGCTGCGGTCGGTGTGGGGACCCCTGAAGGACAACGAG AGCACCATCAGTTTCTACACCCGCCAGATCCTGCAGGGACTTGGCTACTTGCACGACAACCACATCGTGCACAGGGACATAAAAGGGGACAATGTGC TGATCAACACCTTCAGTGGGCTGCTCAAGATTTCTGACTTCGGCACCTCCAAGCGGCTGGCAGGCATCACACCTTGCACTGAGACCTTCACAGGAAC TCTGCAGTATATGGCCCCAGAAATCATTGACCAGGGCCCACGCGGGTATGGGAAAGCAGCTGACATCTGGTCACTGGGCTGCACTGTCATTGAGATG GCCACAGGTCGCCCCCCCTTCCACGAGCTCGGGAGCCCACAGGCTGCCATGTTTCAGGTGGGTATGTACAAGGTCCATCCGCCAATGCCCAGCTCTC TGTCGGCCGAGGCCCAAGCCTTTCTCCTCCGAACTTTTGAGCCAGACCCCCGCCTCCGAGCCAGCGCCCAGACACTGCTGGGGGACCCCTTCCTGCA GCCTGGGAAAAGGAGCCGCAGCCCCAGCTCCCCACGACATGCTCCACGGCCCTCAGATGCCCCTTCTGCCAGTCCCACTCCTTCAGCCAACTCAACC ACCCAGTCTCAGACATTCCCGTGCCCTCAGGCACCCTCTCAGCACCCACCCAGCCCCCCGAAGCGCTGCCTCAGTTATGGGGGCACCAGCCAGCTCC GGGTGCCCGAGGAGCCTGCGGCCGAGGAGCCTGCGTCTCCGGAGGAGAGTTCGGGGCTGAGCCTGCTGCACCAGGAGAGCAAGCGTCGGGCCATGCT GGCCGCAGTATTGGAGCAGGAGCTGCCAGCGCTGGCGGAGAATCTGCACCAGGAGCAGAAGCAAGAGCAGGGGGCCCGTCTGGGCAGAAACCATGTG GAAGAGCTGCTGCGCTGCCTCGGGGCACACATCCACACTCCCAACCGCCGGCAGCTCGCCCAGGAGCTGCGGGCGCTGCAAGGACGGCTGAGGGCCC AGGGCCTTGGGCCTGCGCTTCTGCACAGACCGCTGTTTGCCTTCCCGGATGCGGTGAAGCAGATCCTCCGCAAGCGCCAGATCCGTCCACACTGGAT GTTCGTTCTGGACTCACTGCTCAGCCGTGCTGTGCGGGCAGCCCTGGGTGTGCTAGGACCGGAGGTGGAGAAGGAGGCGGTCTCACCGAGGTCAGAG GAGCTGAGTAATGAAGGGGACTCCCAGCAGAGCCCAGGCCAGCAGAGCCCGCTTCCGGTGGAGCCCGAGCAGGGCCCCGCTCCTCTGATGGTGCAGC TGAGCCTCTTGAGGGCAGAGACTGATCGGCTGCGCGAAATCCTGGCGGGGAAGGAACGGGAGTACCAGGCCCTGGTGCAGCGGGCTCTACAGCGGCT GAATGAGGAAGCCCGGACCTATGTCCTGGCCCCAGAGCCTCCAACTGCTCTTTCAACGGACCAGGGCCTGGTGCAGTGGCTACAGGAACTGAATGTG GATTCAGGCACCATCCAAATGCTGTTGAACCATAGCTTCACCCTCCACACTCTGCTCACCTATGCCACTCGAGATGACCTCATCTACACCCGCATCA GGGGAGGGATGGTATGCCGCATCTGGAGGGCCATCTTGGCACAGCGAGCAGGATCCACACCAGTCACCTCTGGACCCTGAGAGCTGAATGAGGGCAT CATAGGCCAGACAGGCCCAAGGATGGATGAATGGAGAGGACAAAGGCAGCTTCTGACACACCAGCCCCAGGACCTGGGGCGACTGGAGGAAGCCAGG CGAGTGGGGCCCAGGACTGGTTCCAGTGAGAGAAACCAACCACAGGCACCCAAGCACTACCAGACAAAGCGTATTAAACAGAACACTTTTGAAAAAA AAAAAAAAAAAAAAAAAAAAAA HUMAN SEQUENCE - CODING ATGAACTTGCTGCTCTCCTACCGCGATGTGCAGGACTACTCGGCCATCATTGAGCTGGTGGAGACGCTGCAGGCCTTGCCCACCTGTGATGTGGCCG AGCAGCATAATGTCTGCTTCCACTACACTTTTGCCCTCAACCGGAGGAACAGGCCTGGGGACCGGGCGAAGGCCCTGTCTGTGCTGCTGCCGCTGGT ACAGCTTGAGGGCTCTGTGGCGCCCGATCTGTACTGCATGTGTGGCCGTATCTACAAGGACATGTTCTTCAGCTCGGGTTTCCAGGATGCTGGGCAC CGGGAGCAGGCCTATCACTGGTATCGCAAGGCTTTTGACGTAGAGCCCAGCCTTCACTCAGGCATCAATGCAGCTGTGCTCCTCATTGCTGCCGGGC AGCACTTTGAGGATTCCAAAGAGCTCCGGCTAATAGGCATGAAGCTGGGCTGCCTGCTGGCCCGCAAAGGCTGCGTGGAGAAGATGCAGTATTACTG GGATGTGGGTTTCTACCTGGGAGCCCAGATCCTCGCCAATGACCCCACCCAGGTGGTGCTGGCTGCAGAGCAGCTGTATAAGCTCAATGCCCCCATA TGGTACCTGGTGTCCGTGATGGAGACCTTCCTGCTCTACCAGCACTTCAGGCCCACGCCAGAGCCCCCTGGAGGGCCACCACGCCGTGCCCACTTCT GGCTCCACTTCTTGCTACAGTCCTGCCAACCATTCAAGACAGCCTGTGCCCAGGGCGACCAGTGCTTGGTGCTGGTCCTGGAGATGAACAAGGTGCT GCTGCCTGCAAAGCTCGAGGTTCGGGGTACTGACCCAGTAAGCACAGTGACCCTGAGCCTGCTGGAGCCTGAGACCCAGGACATTCCCTCCAGCTGG ACCTTCCCAGTCGCCTCCATATGCGGAGTCAGCGCCTCAAAGCGCGACGAGCGCTGCTGCTTCCTCTATGCACTCCCCCCGGCTCAGGACGTCCAGC TGTGCTTCCCCAGCGTAGGGCACTGCCAGTGGTTCTGCGGCCTGATCCAGGCCTGGGTGACGAACCCGGATTCCACGGCGCCCGCGGAGGAGGCGGA GGGCGCGGGGGAGATGTTGGAGTTTGATTATGAGTACACGGAGACGGGCGAGCGGCTGGTGCTGGGCAAGGGCACGTATGGGGTGGTGTACGCGGGC CGCGATCGCCACACGAGGGTGCGCATCGCCATCAAGGAGATCCCGGAGCGGGACAGCAGGTTCTCTCAGCCCCTGCATGAAGAGATCGCTCTTCACA GACGCCTGCGCCACAAGAACATAGTGCGCTATCTGGGCTCAGCTAGCCAGGGCGGCTACCTTAAGATCTTCATGGAGGAAGTGCCTGGAGGCAGCCT GTCCTCCTTGCTGCGGTCGGTGTGGGGACCCCTGAAGGACAACGAGAGCACCATCAGTTTCTACACCCGCCAGATCCTGCAGGGACTTGGCTACTTG CACGACAACCACATCGTGCACAGGGACATAAAAGGGGACAATGTGCTGATCAACACCTTCAGTGGGCTGCTCAAGATTTCTGACTTCGGCACCTCCA AGCGGCTGGCAGGCATCACACCTTGCACTGAGACCTTCACAGGAACTCTGCAGTATATGGCCCCAGAAATCATTGACCAGGGCCCACGCGGGTATGG GAAAGCAGCTCACATCTGGTCACTGGGCTGCACTGTCATTGAGATGGCCACAGGTCGCCCCCCCTTCCACGAGCTCGGGAGCCCACAGGCTGCCATG TTTCAGGTGGGTATGTACAAGGTCCATCCGCCAATGCCCAGCTCTCTGTCGGCCGAGGCCCAAGCCTTTCTCCTCCGAACTTTTGAGCCAGACCCCC GCCTCCGAGCCAGCGCCCAGACACTGCTGGGGGACCCCTTCCTGCAGCCTGGGAAAAGGACCCGCAGCCCCAGCTCCCCACGACATGCTCCACGGCC CTCAGATGCCCCTTCTGCCAGTCCCACTCCTTCAGCCAACTCAACCACCCAGTCTCAGACATTCCCGTGCCCTCAGGCACCCTCTCAGCACCCACCC AGCCCCCCGAAGCGCTGCCTCAGTTATGGGGGCACCAGCCAGCTCCGGGTGCCCGAGGAGCCTGCGGCCGAGGAGCCTGCGTCTCCGGAGGAGAGTT CGGGGCTGAGCCTGCTGCACCAGGAGAGCAAGCGTCGGGCCATGCTGGCCGCAGTATTGGAGCAGGAGCTGCCAGCGCTGGCGGAGAATCTGCACCA GGAGCAGAAGCAAGAGCAGGGGGCCCGTCTGGGCAGAAACCATGTGGAAGAGCTGCTGCGCTGCCTCGGGGCACACATCCACACTCCCAACCGCCGG CAGCTCGCCCAGGAGCTGCGGGCGCTGCAAGGACGGCTGAGGGCCCAGGGCCTTGGGCCTGCGCTTCTGCACAGACCGCTGTTTGCCTTCCCGGATG CGGTGAAGCAGATCCTCCGCAAGCGCCAGATCCGTCCACACTGGATGTTCGTTCTGGACTCACTGCTCAGCCGTGCTGTGCGGGCAGCCCTGGGTGT GCTAGGACCGGAGGTGGAGAAGGAGGCGGTCTCACCGAGGTCAGAGGAGCTGAGTAATGAAGGGGACTCCCAGCAGAGCCCAGGCCAGCAGAGCCCG CTTCCGGTGGAGCCCGAGCAGGGCCCCGCTCCTCTGATGGTGCAGCTGAGCCTCTTGAGGGCAGAGACTGATCGGCTGCGCGAAATCCTGGCGGGGA AGGAACGGGAGTACCAGGCCCTGGTGCAGCGGGCTCTACAGCGGCTGAATGAGGAAGCCCGGACCTATGTCCTGCCCCCAGAGCCTCCAACTGCTCT TTCAACGGACCAGGGCCTGGTGCAGTGGCTACAGGAACTGAATGTGGATTCAGGCACCATCCAAATGCTGTTGAACCATAGCTTCACCCTCCACACT CTGCTCACCTATGCCACTCGAGATGACCTCATCTACACCCGCATCAGGGGAGGGATGGTATGCCGCATCTGGAGGGCCATCTTGGCACAGCGAGCAG GATCCACACCAGTCACCTCTGGACCCTGA

[0294] TABLE III MOUSE NOMENCLATURE ICSGNM      Fosb Celera      mCG4848 HUMAN NOMENCLATURE HGNC        FOSB Celera      hCG20725 MOUSE SEQUENCE - GENOMIC CTCACTCCGCCAGTCTGAAGCATCCGGGCTCTGTCTGTGAAACAGTCCGCGAACTGGGAGGGTCTACCCACTGGCCCCAGCACCCCTCCTCCCAAGG CCCCCCATGCTGCTGCTTCATGTGACCAGGGCTGGGCCGAATCTCTGAGCAGACAGAGAGAAGCATGGTGTGACCGCATGAGTGGAGTGAGTTCTGG GGACAGTGCCCAGTTGTGCGATAGACAGCAGATTCCGGAGGACCACTGTGCATGTGTGTGTGTTGTTGTATTTGGTTTGTGTTTGTGAGTATGTCTG TGTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGACAGACAGACAGACAGAGACAGAGACAGAGACAAAGAGAGTTGTGTGAGGA CCACTGTGCATGTGTGTGTGTTGTGTGAATGTTTGTGAGTGTGTGTGTTGTTGTATTTGGTTTGTGTTTGTGAGTGTATCTGTGTGTGTGAGAGAGA GACAGAGAGACAGAGAGAGAGAGAGAGAGAGAGAGACAGACAGACAGACAGACAGACAGAGAGACAGACAGAGAGAGACAGAGAGAGACAGAGAGAG AGAGAGAGTTGTGTGAGGGCCTCCCAGGTGATCTGGGAAGCTTGTGAATGTGAAAGTGCCTGTGGGTGGCTTCACCTCTGGCAGAGGCATTCTGCCT CCTGTATATTAACTATGTGTGCTCAGACAATCCACTCAAAGATGCTCTGGGGCTGCAGCTGATAGAGCAGCTTACTTAGTGTGCACAAGGCCGTGGG TGCAAACACCCCAGAACTACAATCCCAGAACTCTCTCTGCGCACTGAACTCGACTTCCTCATTTGTTTCTTGTTTCTTTTTTTTGACGGAGTCTAAC ATTGTCCGGATTGCTTCAAACTTTATAGCGGAGGAAGATCGATGGCAATTCTTCTGCCTCCACCTTCTGAGTGCTAGGATTGCAGGCATGTACCCTC ATGCCCAGTTGAGACAGTATCAGTGATTGAACCCAGGGCCTCACGCCTCCTGGAGAAGCCCTGTACCATGGAGCTACAAGTCTAGTTCCTTTTCTTG TCCTTAAAAAAAATAAAAAGCTGGGTCTTCTTATAGCCCAGGCTGGCTTTGTACTCCCCATCCTCCTGCCTCAGCCTCCCAAGTGCTGGGATGATAG GCTTATGGCACGGCCATGATAGCACCTACAATTTCCAGAGTTGCCTGTCCTTTGCAGTGTACTATGCCTTGTGAGGGACAGGCTCTGAGGGTCTGCT TGTGATCACACACCTGAGGACCTGTTTGCTGGGAGTTCTGTCCCCATTTCTTTGCCAGGCTGGAAGACACTGACACACCCACCATGGTGACAGTACC CATGGACTTAAATGGTGTGACTCCCTCTGCTCTAATGGGAGGGTCTCAGTGCCCCGTATCTGCTGTTTCTCAAATGGGGTAGGTAATACAGAGATAG GAGGGCTGACACAAAACATATCAAACACCAAGATAGCAAAGGCTAGAATGAGACCCTGTCTCAAGCTTTCCCATAGAGAAGGGGAGTGTATAATTGC ACCCACTCACAAGACTGTTGGCCATAAACAAGTTTGTATGGAAAATGTTTACAAAGTGCTTGGCACATCCAGGGGTGGTGGCGCACACCTGGATTCT CATACTTGGAGAGAAGAGCCAGGAAGATTAGGGACGGTTCCAGTCAGGCCTACATATTGAGACCTTATCTCAAAAACAAAACAACACAACACACACA CACACACACACACACACACACACCTCAAAAACCTCTGGAAGTTCACATTTTGGGAAAGGCATCTGAATGGTAAAGTGTAGGGATTAAGAGTAGAGAC TAGAGTCCCTCCATGGGACCGAGATGTAGAAAAGAAAGAAAAGAGAGCTTGCTAAAGCAGGCCAGCCTAAGGGCAGACTCCTGAAAGGACTTGCTCC AAATGATTGTTGAGGGTGGAGGACTCTAAGAAACTGGAATTGTGGGAAAAACTCTCGGGGAATGACAAAAGCCGGTTTGCAGGTTGGTGAGATTAGA AAGTAATGGCCACAATATAGGGCACAATATACAGGCTGGTCTTGAACTTGTAATCCTCCTGCCTCAACCTCCCAACTATTATAGGTATATGTCACCA GCTGGATGCTTTTGCCTGTCTTGTTTCTTTCTGTGCCCCAGGGCTTCAGTGAATAGGGATGGCTGCCGATTAAATAACTGAATTGCTAGCAGGGTGG GTGAGTCAGGGCTTTAATCCCAGCCTTCAGGAGGCAGAGGCACACAGATCTTTGTGAGTTCGAGGCTAACCTGGTTAACAGAGAGAGTTCCAGGACA GTCAGAGCTACACAGAGAAACCTTGGCTCAAAAAACAACAAAATATCTGAATGGCTGATTGAATGACTGGGCAGATGGACAGATAGACAGATGGACA TGTACGATCCACRGACATGTACGATCTTTGGGATGGTGGGGAAGGCTTGGTAGCTAACACAGGCTGGCTCAAGACCTGCTTCTGGGAACCCTTTCTT TCCTTTGTATCCTCAGCTCTGGGTCATGAAGGGTGTGGAGTGGGCCGGGAAGGGAGTGTCAGGCTCAGTGGCTGCTTGCCTTGGATTCTGGCCCAGA GTGTCTGGAGGAAGAAGAGGGTATCTCGGCATCTGAGTCACCTTAGAGAAACCCTAGCCACATACCTGACTTCTGACATCACACAACCAGGGCAACC CTGGTGGCCGAGACAAGGAGACTGAATCATGGACTGAAATCAGTCACCTTGGGCATGGGCACGTGGCCGCTAGTGACCCCCTGAGACACCCCCGAGT GGCTGTCTGGCTGTGTGGGCATGCAAACCACATCAAGGTCAGTAAAGGCTCTCCAGCCTGAGTCAGGGACAGGGTGGCCACTGCCAGAGACCACCGA CCACAGCATCTGCAGGACAGGAAGAGAAAGTTGAGGGAGAAAAGGCAGAGGGTAGGCCCCAGTCAGGGAGAGGGAAGTGCCTGTGGGAGAAAGGGGA AGCTGTGGCTTGCGGCCAGTAGCCTGGTGACCTGTGGCTGGGATGTGGAATGGGGTCTTAGTGTTTGCGCACAGAATGGCGAAGTTGCAAGCGAGGC TCAGAGGACAATGGAGTCAGCAGACAATGGGCTCTTACACTTGCACACGCAGGCACAGGCGCACAAAAGCCAGCGTGGGAGCCCTACCCTCCAGCCA CCCCAGAGCTACAGCTTGCCACACACACACAAGACTGTCCCCACAAGACTCGCTTCCTTTACCCTATTAAGTGACATCCGTAATTCTCATTGTGAAG ATTGCAACTCTCGGTATTTTGATGATCTCATTTGATATGAATAACTTAGACATTTGCAGTGCCAGGCACTGTTGTAGACTATTTAGCTGTGCTAGGG ATTGAACCCAGGGCTTCTTGCATTCTGGGCAAACATCCTGCCACTGAGCTTGCTCCCAGACCCACGTGCCCATGGTTTGTCCCCAGACCCCTGTTTT ATATGTAATTCTGAGACAAGGTCTCACTGTAATGCCCAGAGACCCTTGAGCTCACTCTATTACCCAGCCTTGAACTCACTGATCCTTCTGCAGGGAT TGTAGGCATGACTAGCTAGACACAGCTAAGTATCTGTTAGAGCGTGTATGTGTACCTTGGGGCAGACATCTGTCCAACTGTATATGTCTATACATTG TTAGGTTTCAAACAAATGGCTGAGGTGCCTATTTAACATATCAAGAGGACCTGGCCCCCAATTTCTCCCTGCAATAACTCAGCTCCTATATGCCCTC CTGGCTGGCATACCCCACCCGCTATGCTGAACTTCTCCAGCCCAGGGGCTGGGCTGTTCATCCCTATGTAATCCAACTATTTTAGCTCTCCCCTCTC TTTGTACCTTAAGGCTGCACCTGGCTCCCATGGCTCCCCTCCCTCTCTCCCCACACGGCTCAGGGTTAAGTCGACTCTGGACTATCCTAGAGGTCCC TGCCTCTGGCTATGCTCTCCCACATATCTATAATAAACTCTCCTCTGCATACCTAGGAACAGTCATGTTCCCTTCCTTTCTCTTTCTTAATTTCCTT TTCTTTTCATTCATACATACGTTTCTTTGGATTCTGTATTCTATTCTCCCTCCTTAAAAATATACACAGCTAGCCAGGCATGGTGATGCACACCTTT AATCCCAGCACTCGAGAGGCAGACACAGGTGGATCTCTGTGAGTTCGAGACCAGCCTAGTCTACAGATTGAGTTCCAGGCCTGTCTGGCCTATACAG TGAGATCCTCAAAAAGAAAAATGTACACACACTACCCCCTTCAAGTCAGAAGACCCTGAGACACAAGCCCATCCATCGCCGGGCAGCATGGGAAAAG CAGGTTGTTACAAATGCCTGGAGTCAGGTCTGACACTCACACACAAGGTCCCTGCCACCAGTTGATCCAGCAGCTACATTCGAAGGATCAGAGAGGT CCAGATAACTGTGCTGCCCTGTCAGACCTTATGAATGAAGACCTGAATGGAGGCTGATGTCTGTAATTCCAGCACTCGGGAGGCACTCAGGAGGCAA GGAGGATTGGAGGGAGTTAGCTGGAGGCCAGCCTATGCTATAGAGTAAGACTGCTTCAAACAAGAGAAATGAGAACTGAAAAGATTGCTCAGTGGGT AGAGGCGCTTGCCTGCAAGTCTAAGGAACTGAGTTCAATTCCTGACATTTGCATGATGGAAGAAAAGAAACTCCTTCAAGGTCACACACACACACAC ACACACACTCAAAGAAGTAAAAATACTTTTTAATTTAAAAGAACAGAGAAACTTGAACACATGGTCGGTCTGCGATGTGGCTCTGCAGTAATGCCTG CCTTGGATGTATGTAGTCCTGGTTTTGACCCCACCATTATACAGACCAGGTGTGGTGATACAAACCTGTAATTCCAGCACTGGGGGCTGGAGCCAAG ACGATGGGAGAAGTTCTAGGTGGCTCATCCTTGGCTAAAAAAACATAGCCTGAGCTACCTGACACTGGTTGCTAGTGTGAGCTATCTGAGACTCTGC CTCACAAATAATTAAGTAAAAATATGGTAGATTCATGACGACAGCACCTACAGATTGCCTGTCCTGTGCTGGGACACAGGGCAGCTTCACACTAACC CTGATGGGAACACCTGGGAGACGACATGCTTGTTGCAAGGCGCTGGCTCATCTGAGACCAAAGCGACTTCAGGAGCCAAGTAGACCAGAATCCGTGT GCTTCAGACAGTGGGAAGGGCATACAGAAACCTCAGGAACTGAGGCACAGCAGGGAGATGGGAGGCTGGGACAAGGGACCACTGACAGACACCATAC ATCATACCATCTTGTCCCTCTGAATCTCCATGGGCACCCCCTCTGGGAGGACTCCAGGACTGCAAGCAAAGGTTAACTGAGTCAGCCAATTCAACCC TGGCCTAGGGGGTGGAGGCAGGGGGTCTATCAGCGCGAGGAGACAGGACAAGGACACTCATGTATTGCCATAGGGATGGCTCTCTTGTCAAACCATC AGAACACCCACAAACATCCCGGCTCACAGGGGTCTGCAGGGGTAGGGCTGGGATGTGGCCCGAGACTTGTGGGAACTGAGGAATGTAGTGGCAAAAG TTTGGCCAAGGGAAGACCAGAGGACTCTGTATGCATGAAGGCCAGGGTGATGACATTTCAGGAAAGAAAAGCACAGAATCAAGCATGGTAGGTAGTT GGAAAGTGGAAGCGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACCACATT TACTAAGCCCCTCCCTGCCAAAGTAAGCAATAAATTATGGCTAAGAGTCTCCCCACTCCTAAGATGGAAAGATGCCAAGCTGCAAAGGAGATCCTGA CAACAGACCAGCTACTTGGAAGACTCAGAACCTAGCCAAGCTGCCTGCAAGAGGTTTAGACCAACTAAGACATCTGGAGAGAGCACCCTCCAATCTG TGGAGCAGTCTTCAGGCTCTGCAGGGTGCTCCAGGCTCCCAGCTTTGTAAGCTGTCACTCATGCTGGGGCGGGCTTGGGTGACGCAGCTGTCTTTGA GTGACTTCTCCCGTAAGTCACCCCTCAGCCATGCACACTCCTGTAAGTAACTCTAATAGAAAATTCATCGGTTCAGCAAATTGGACTTTGGTCTCTT CTGAGCTGGCTCCCTGTCTAGGGTGAATGGACATGTGTGTGTGGCATCTCCCCTGGAAAAGTTTTCTTTCCCTAGGCTTGGCCTGGGGTCTCCCAGG CTTTTTGCAGTTGCTGGTGGCATCCTTCTTAGTGGGTACTTAAGAATCAGGACCCTGGCCAGCGATGCAGCAGCCGTTGGCAGAGGGCTCCCCTAGC ATGCAGGAGGCCCCTGGATTACATCCCCAGTAATAAACCAGGCCTGGCGACAATATAGAGGTGAGAGCAAGATGTTCATTGTCATCCTTGGGTACAT AGTAAATTCTAGTCTTTGTTTTAAAAACAAACAAACAAACAAACAAGCAGGACATAACATCAGATATGCCTGGCATGGTGGAAGGTGCCTTTAACTC CAACACTCAAGAGGTAGAGGTCATCCTGGCCTACAGAATGAATTCCAGGCCAAAGGTGGTACATAATGAGACCCCATCTCAAAAACAGACAGAGAAA GGAGGAGGGCAAAGGGTAGAAAGAGGAGGGGATGTTCACAATAGGGGGAGGGGATGTTCACAATACGTGTATATATATTCTTTCCTTCTGGATGTGG ATAGAACCCAGGACTTCACACATGCTAGACATTCATTCCACTTTAAGCTACATTCCCGCCCTCACATCCCCTTTTGTTTAAATCATTAATATTGATA TTATTATTATTATTATTATTATTATTATTACTACATATGAGTACTGGTTGTTTTCTGTCTTTGCATGCATGTGGAGATCAGAGAACAATTTTTAGGA GTCATTTTTCTTCTTCCACCGTGAGTCCCAGGGATGGGACTCAGGTTGTCAGGTATGTGTAGCAAGCTCCTTTACCTGTGAACCATCTTGCTGGGGC TGATACCTGCTGATTGCTAAACACATGCCACCGATTATATTAATGCACTAGTATTTTATTTATTTATTTTTCGAGACAGGGTTTCTCTGTGTAGCCC TGGCTGTCCTGGAACTCACTCTGTAGAACAAGCTGGTTTCGAACTCACAGAGATCTCCCTGCTTCTGCTGGGATTAAAGATGTGTGCTGCTGCCGCA GCTGCCACCACCACCAGACACCACCAATTATTATTGTTCAATTATTATTGTATACACACTTTCTTTTCTGTCTCCTGAGCTAAGTGGGAAGGAGAGG CTTCCAACACCATCAAGCCTGAAGAACTCACCGGGTGTGGGTTCCTACCTGCTCCAATTCTGCAGGTCCCCCAGATTCAGGGACCCGGAAAAGCCAC CTATCCTTTGCTTAGCTATGAGTACTGAAGTTTTAGATCAGGGAGGGAGCACATTTTCCAAGCTCACCGAGTCACACAGAATCCGTGACAAAGCTAG TGGGGAGGGGACTGCATCCTTACCCATCCCTACACCTGGGGATATCACAGACTCTCCAATTCCCCCTGAGCCTCAGTTTCCCCACCTAGACTGATTA TACCCCTCTCGCCAGAATCTGCACTGGGGACCTTGCTCTTTTTCACCAGCAGGGGCGCTGCACCGGTTTGGGGAGGGTGGGGTCCCAGGGGTATAAG CAGACCTGGGATCTGGAGTTGCACCTTCTCCAACCCGGGTCAGCAGGGGCCTTCTGAGGGAGTTTAGGCGCCTGTCAATCTCAGCCTCCGGGACAGC GTGGAACTGCGCAGGCGCGGGCGGGTTCCGCACAGCGCAACAGCGGGCGCGCGCGGGAGCGAGGGATTCCCTCTGACGTAATTGCTAGGATACCAAA CAAACACTGGGCCGCGCTGGCCGAGCTCCTTATATGGCTAATTGCGTCACAGGAACTCCGGGGAGGGCGGGGCGGGATCCCCTCCCGCGAAGCCCCT CAGAACGCAGCCTTGGGGACCCCCGAGACCCCCAGGGTCACACTATGGGCAGGTGGCAGGTGCACGAGGCCCTGGAGGGCGCCACAAGGAGCTCAGT CGGCGGGAAGGGAGAGTTTGGGAGGTTTGTGCATGGAGTTGCGGGTGACGCAAGCGCGGGGGGCGGGTCCCGGAGGCATAAATTCAGCCCGGCAGCT CCCGGTTTCATTCATAAGACTGGAGCGGCTACGCCGGGGACACGCGGAGCCGGGGCTTGCTGGACTTGACTACTGGTGACTCTTTCTTTTTCTTCTT CTTGGAGGCCGTGAAAAATTTATATATATATATTTATATATATTTTTAAACTGGAGAGAAAGTTTTGTGGGTTTCCTTTTTGCAAGACTCTTTCTAG ATCGTTCTTCCGATTCGTCCGGAGGATAGACTTTCTTTCTGTGGGCTTCTGGATCGCGCCCCTCTGCTCTCCCTCATTTCTTGGGACGCTTCGACAG GATTGGAACTGCATCTGAAGCGCACGCTGCACCGCGGCACTGCCCGGCGGGTTTCTGGGCGGGGAGCGATCCCCGCGTCGCCCCCCGTGAAACCGAC AGAGCCTGGACTTTCAGGAGGTACAGCGGCGGTCTGAAGGGGATCTGGGATCTTGCAGAGGGAACTTGCATCGAAACTTGGGCAGTTCTCCGAACCG GAGACTAAGCTTCCCCGAGCAGCGCACTTTGGAGACGTGTCCGGTCTACTCCGGACTCGCATCTCATTCCACTCGGCCATAGCCTTGGCTTCCCGGC GACCTCAGCGTGGTCACAGGGGCCCCCCTGTGCCCAGGGAAATGTTTCAAGCTTTTCCCGGAGACTACGACTCCGGCTCCCGGTGTAGCTCATCACC CTCCGCCGAGTCTCAGTACCTGTCTTCGGTGGACTCCTTCGGCAGTCCACCCACCGCCGCCGCCTCCCAGGTAAGTTCTAGATCGTAAAGATTCTAC TTTAGTGGTTGGGGGGGGGTGTTTCTTTCAGGCTAAAGTGTAGATTGAGCATCCTCTCAAATAGAGACGCGCCAAAACCCAGGATCTGGGATTGCAA TAGTTCGGTTTGCACTTTGGTTTTTTGTTGTTTGCAAACTGCAAAGAATGGAGTGATGTTTGCAAAAGGTTATTTGCGCGGAGCGCGGGAAAGGAAT GCAGCTGGGCAAACGTTGGCGATGCCCGGTGCAAAGTATATACCCGGTGGTTAGCAGAAGCTGAGAACTTTTAGCCGAAAGCCGGCTCCCTAAGCCG AAGCTAGGCAAGTAGGGGAAGAAAAAGAAACAAAAAATTCCAGAGAAGCTTCCAGGAGCCTCCTCCTCTTCCCTCTTCCTTCAAAACGCGGACTGCA AGTCCGCAGTCACCCTCCACCCAGCAAGAGTTAGGGCCTCGAACCCCGGTCACGCTGCCTCCGCCTCCTGCGCGGAGACGTAACGGGGGACCCGTGC GTAAAGGCTGACGCGCTGGAATCCTCCGTCTGACGCGGGGCACGCACAGCGCGCAGCGCCCCCTCCGCCCGCCCCGCCCCTGACGTCCCGGGCACGT TCTATTTTGGAACGCCGAGGCCACGTTGCTAAGGGAGGGGGCAGCGTGGCTTTGTGATTGGCTGTCGCGGCGCGAGCTTTAGCCAATCAGCGTTCCC TTCCTATTTGTAGAGCGTAGCTCCCTTCCTTGCTTTTTGTGGTTCTTCCCGTGCTGGGGGTCTCCAAGAGGGAGAGCTAGGGGATTCTTGTCGCGAT CGGGGGACTCGTTGTCACCCCATGGGTCTGCGAGGACCTTGTGTGGACCTGGTCCTGTTGTCATAAGCTAGAGGCTTTTGGCTGAGTGTTAGCGCCT CTAAGGGGGAACTGAAGGCCTCATCCCTTCTCCAGGCACACATATACGTGCTCCCTGAGCTCTAGACACTCAGTCCTTCCGAGGTGTTCAAACACTA GATGAGCTAGCCTACGGAGAGGCAGCCAGGTGGTCTCTAAAAGGTCCGCCTTCCCTTAGTTCCCAGGGCTCTGATTGGCCAGGGATTCAGCCCTTCC CTCGCCACGCCCCCTAGAGTAGTTAAGCCTCTAGGATTCCACTTGCGGGAAGGGGGGGGGGGGCGTGATGGACGCTTCTTGGGTTCGGGGACGCAGA TCCTATGTCACCCCATCCCCTGCAAGACAGTCTGAGAGATTCTCGCTGTCACTTTTCTCTGCCTATCAGTTCACTGAAACCTGTCAGTCTCACTGGG GAAGAGACAGACACTCGGAAGGGATGCTCTCAACTCTTAGGCCGGTCCCCCAACACCGTTGGAACTGGGATCTCCGCCCCTGCGGGAGCCCTCATGC AGTGGGGGGTGTGTTTGTGTGTGAGTGGAGGAGAGGAAGGCTTGGGCTAAGGCCTCTCCCTCTCCCTACCTACTGTGGTGGGGGTGGGGTGTTTTGG CTGTATGTGTGTGTGANNNNNNNNNNNNNNNNNNNNCTGACTTGAAGGGGGTAGTGTGTGTACATTTTTCTTTTTGAGACAGGATCTCACTGTATAG GCCAGACAGGCCTGGAACTCAATCTGTAGACTAGGCTGGTCTCGAACTCACAGAGATCCACCTGTGTCTGTGGCTCCAGTCCCGGGATTAAAGGTTT GCATCACCAGGTTCTGTCCAGCCTCCGTCTCCCACCCACCCCCCCACACCTAAGAGTCACCAACCCGGGGTGTGATTCACCACCCGCTGGAACCGTG CAACCTTTCCCCGAGGAAGAAGGAGGAGGTAGAAGGCAGTTGAACAGAATCTCTCATTAACCACTGCGTCACGGTGTAGTGGAAGGGTGGGTGTTGT GGCTTTTTGCCTGTGACACACACATCCACACCCGCTCACCCTGTGCTCACTCACAGGGGTCGGTGTGTGTTATGTGTGTTGGGCGTGTGTGTGTCGG TGGCTTTGTTTGTGTGTCTACGCCTGTGTGTGTATGTCTCACCCCGTAGGAGTGCGCCGGTCTCGGGGAAATGCCCGGCTCCTTCGTGCCAACGGTC ACCGCAATCACAACCAGCCAGGATCTTCAGTGGCTCGTGCAACCCACCCTCATCTCTTCCATGGCCCAGTCCCAGGGGCAGCCACTGGCCTCCCAGC CTCCAGCTGTTGACCCTTATGACATGCCAGGAACCAGCTACTCAACCCCAGGCCTGAGTGCCTACAGCACTGGCGGGGCAAGCGGAAGTGGTGGGCC TTCAACCAGCACAACCACCAGTGGACCTGTGTCTGCCCGTCCAGCCAGAGCCAGGCCTAGAAGACCCCGAGAAGAGACAGTAAGTATGAGGCCTCAG GAGTTGGGATGGAGGAGCCTAGCTAGGGATGTGGGCTCAGTTTGTACAGTGCTTGCTGCCATGCATGAAGATCCCTAGCACAGCATAAGCCAGGAGT GGTTATGCAGACCTGTAACCCCAGCTCTCAGAAGGTGGAGGCAGGAGGAGCAGGAGTTCGAGGCCAGCCTGTGCTACTTATGGAGTCCAGCCTGCAC TGCAAGAGATCATTATTTTCAAAAGTTGGCCTTGGGGGGAGGTGGGTGAGGGAAGTAAGAGAAAGTGACAGTAATTTTATCACTTAATAGTTGGAGG TTCCTCTGAGGCCTCAAGTCTGAAGGAACTTTACCATTCTGGCCAGTGAGGAGTAGGGGTTATTATTTGGGGTTCAGGAGGAAGGAGTTTTCTTAGG GCTGATAGAGGTACCCCCAGATCTCATGGTCCTTATCTCTGACTCAGCTTACCCCAGAAGAAGAAGAAAAGCGAAGGGTTCGCAGAGAGCGGAACAA GCTGGCTGCAGCTAAGTGCAGGAACCGTCGGAGGGAGCTGACAGATCGACTTCAGGCGGTAAGGAGGAGTCTGGGGGTGTCTTGAGGCCGTGCTGGG AGCACTCTGCCTTGTTCTTCCCCCGTTTCTCACTGTGCCTGTGTCCTAAACGAGGAAACCCCCTCTTAGGGAACAGGGGTCAGTATAGGCTGATGGA GTGGCTCCATATGCATGCTCAGACCCATGCCCACTTACTTTCGACTGTTCCCCACTTTCCCTGAATATGTCCCCACATGTCACCCTCCTGGCTTTCT CTCAGCCTAAGGAGACAAGCTGGAGGAGGTAATTCTCTCACCTTCTTTCCTTCACTAAATAATAATCCATTTTGCCTTCCTGCCTCCATTTTTTTTT CCTGAGCTGGGGATCTACCTGTGTAGTTCAGCCCTCCTCCCCCAACTTGATAGCCTCAAGTTTCAGCCCTTGGCTGAGATGCCATCATCCTGACTGG CTCTGGCTGGAAACTATTTTGTGCTAAGTCAATTCCTTACCTGCTACTCCAGCTATCTACAGTTCTGCCGAACTTGAGCTGGTGGCGCCCACCAAGC CCACTTCTTTCTCTCTTCTACCTCAGTGCAACCCCCACACACACACACACACCTCATGCCTGCCCCTTGAAACCAGGGTGTGTCTCTGATTTCCCGT CGGGAGGCTGAAGGAGATGGGTAACAGAACCTCATTAAAAACAACACATAAGCATTACCTACTGACTCAACAAACTGTAGTGTTTTTCTTTTTTCCT CTCAAAAAATTATTTCGTTTGTTTATTTATTATTTGCTTATGTTTGAGTGAGTGCTGGTGCACCACAGCACACATACGAGGTCAGAGGGAAATTTTC ATAGTTTGTTCTCTCCTTCCGTGTTGTGGGTGCTTGCTGGCAATCTCCTTCACTCAGTGAGCTACAATGCCCCCTTCTGCCCTTTAAGGCAGAGTAC TCCTTAGTACAGGGGGACCCTTTCCTCGGCCTCTCAAAGTTGAGATTACAAATGTTCACCATCACACCAGGCTTGGAGTTCTTGCCTATCAGTGACG TCCACTCCTGCCTAGCTTCTTCCCAACCATCTGTTAGTCTGATGGGGAAACCGAGGCACGAGTAGCATGGTCTACCAGGATTTCCTCTTAGGGGACG GTCCCCTCAGTTGGGAGGGAGCTGTCCAGCCCCCTGGATCAGCAGCAAGAATGTATGAGTGTGGGGTTGGGCGGGTGAAGCTACTCTGTGTGGTCGC TGACCAGCAATTCTCCTTTCTCTGTCTCCTATGACCTGGCCCTGCTGGGATCCATTAGGAAACTGATCAGCTTGAAGAGGAAAAGGCAGAGCTGGAG TCGGAGATCGCCGAGCTGCAAAAAGAGAAGGAACGCCTGGAGTTTGTCCTGGTGGCCCACAAACCGGGCTGCAAGATCCCCTACGAAGAGGGGCCGG GGCCAGGCCCGCTGGCCGAGGTGAGAGATTTGCCAGGGTCAACATCCGCTAAGGAAGACGGCTTCGGCTGGCTGCTGCCGCCCCCTCCACCACCGCC CCTGCCCTTCCAGAGCAGCCGAGACGCACCCCCCAACCTGACGGCTTCTCTCTTTACACACAGTGAAGTTCAAGTCCTCGGCGACCCCTTCCCCGTT GTTAGCCCTTCGTACACTTCCTCGTTTGTCCTCACCTGCCCCGAGGTCTCCGCGTTCGCCGGCGCCCAACGCACCAGCGGCAGCGAGCAGCCGTCCG ACCCGCTGAACTCGCCCTCCCTTCTTGCTCTGTAAACTCTTTAGACAAACAAAACAAACAAACCCGCAAGGAACAAGGAGGAGGAAGATGAGGAGGA GAGGGGAGGAAGCAGTCCGGGGGTGTGTGTGTGGACCCTTTGACTCTTCTGTCTGACCACCTGCCGCCTCTGCCATCGGACATGACGGAAGGACCTC CTTTGTGTTTTGTGCTCTGTCTCTGGTTTTCTGTGCCCCGGCGAGACCGGAGAGCTGGTGACTTTGGGGACAGGGGGTGGGGCGGGGATGGACACCC CTCCTGCATATCTTTGTCCTGTTACTTCAACCCAACTTCTGGGGATAGATGGCTGGCTGGGTGGGTAGGGTGGGGTGCAACGCCCACCTTTGGCGTC TTGCGTGAGGCTGGAGGGGAAAGGGTGCTGAGTGTGGGGTGCAGGGTGGGTTGAGGTCGAGCTGGCATGCACCTCCAGAGAGACCCAACGAGGAAAT GACAGCACCGTCCTGTCCTTCTTTTCCCCCACCCACCCATCCACCCTCAAGGGTGCAGGGTGACCAAGATAGCTCTGTTTTGCTCCCTCGGGCCTTA GCTGATTAACTTAACATTTCCAAGAGGTTACAACCTCCTCCGGGACGAATTGAGCCCCCGACTGAGGGAAGTCGATGCCCCCTTTGGGAGTCTGCTA ACCCCACTTCCCGCTGATTCCAAAATGTGAACCCCTATCTGATTGCTCAGTCTTGCCCTCCTGGGAAAACTGGCTCAGGTTGGATTTTTTTCCTCAT CTGCTACAGAGCCCCCTCCCAACTCAGGCCCGCTCCCACCCCTGTGCAGTATTATGCTACGTCCCTCTCACCCTCACCCCCACCCCAGGCGCCCTTG GCCGTCCTCGTTGGGCCTTACTGGTTTTGGGCAGCAGGGGGCGCTGCGACGCCCATCTTGCTGGAGCGCTTTATACTGTGAATGAGTGGTCGGATTG CTGGGTGCGCCGGATGGGATTGACCCCCAGCCCTCCAAAACTTTCCCTGGGCCTCCCCTTCTTCCACTTGCTTCCTCCCTCCCCTTGACAGGGAGTT AGACTCGAAAGGATGACCACGACGCATCCCGGTGGCCTTCTTGCTCAGGCCCCAGACTTTTTCTCTTTAAGTCCTTCGCCTTCCCCAGCCTAGGACG CCAACTTCTCCCCACCCTGGGAGCCCCGCATCCTCTCACAGAGGTCGAGGCAATTTTCAGAGAAGTTTTCAGGGCTGAGGCTTTGGCTCCCCTATCC TCGATATTTGAATCCCCAAATATTTTTGGACTAGCATACTTAAGAGGGGGCTGAGTTCCCACTATCCCACTCCATCCAATTCCTTCAGTCCCAAAGA CGAGTTCTGTCCCTTCCCTCCAGCTTTCACCTCGTGAGAATCCCACGAGTCAGATTTCTATTTTTTAATATTGGGGAGATGGGCCCTACCGCCCGTC CCCAAAAAGCACTTATATCTATTATGTATAAATAAATATATTATATATGAGTGTGCGTGTGTGTGCGTGTGCGTGCGTGCGTGCGTGCGAGCTTCCT TGTTTTCAAGTGTGCTGTGGAGTTCAAAATCGCTTCTGGGGATTTGAGTCAGACTTTCTGGCTGTCCCTTTTTGTCACTTTTTTGTTGTTGTCTCGG CTCCTCTGGCTGTTGGAGACAGTCCCGGCCTCTCCCTTTATCCTTTCTCAAGTCTGTCTCGCTCAGACCACTTCCAACATGTCTCCACTCTCAATGA CTCTGATCTCCGGTCTGTCTGTTAATTCTGGATTTGTCGGGGACATGCAATTTTACTTCTGTAAGTAAGTGTGACTGGGTGGTAGATTTTTTACAAT CTATATCGTTGAGAATTCTGGGTGGAAATGTCTGATCAGGAGAAGGGCCTGCCACTGCCGACCACAATTCATTGACTCCATAGCCCTCACCCAGGCT GTATTTGTGATTTTTTTCATTTTGTTTTTTTGTATTTrGCACCTGACCCCGGGGGTGCTGGGGCAGTCTAGCACTGGGCAGCTCCCCTCCCCCCCTT GGTTCTGCACTGTCGCCAATAAAAAGCTTTTAAAAAACTGTATTCTTCAGGTCAAAGTGTCTGTTTTCCCTGGACATCTACTACATGGCTTCCTTTC AGAAAAACGGAGTTTGGATTGCTAGGGAGGTCTTGCTGGCACTTAGTGGGACGCCTAATGAATCAGAACCTACAACGGGACTAAAAGGAAGTGGAGA CTTGCTAGGTTTTCCCATGTTCCCAGGCTGGGCCACCTACTTGAAAAAATAAGGGGCGGAAAAGTGTAAGGTACAAATTTGGTGAAGGGTCTGGAAG ACTTCATGATCGGAAAAGAATTTATTCACCTTGGGTGTGCAATGACTTCAGCAACAGCTAAGGGCAAGGTGTAAAAGCTGGGCACACTTGTAAATCC TAGCATTTGAGAGGTGGAGGCAAGGGGATCACTGGTGGAGTTCAGTGTCATGTGGATCGTAGATACCAAGCGCAAAGATCTGCTATGGGGAGAGGGC TTGGTACACCAGGGGAGCCAGAAGTTCGTGGTGAGGGTAGTGGAGGGCAGGTGGAGAGTGAGAGTTAGCCTCAGGGAGATTCTACAGGCAATGATGC AGAGTTCAGACGCTCCTTTGAAAGCACTAGAGAGCCGCAGCAGGTTTTGAGCAGAGAAGGTTAGCGTTAGGTGGTCTCTTCTAGCCCATCCCAGGCT GAGGAGGACGCTGAGGGTTTCAAGAAGGATCGAGAATGGAAAGCAGAGGAGAAAAAGGATCCAAGAGGCATGGAGGAGGCAGAACACATTTCTCTTC TTTAATAGCAAGCCTGGAAAGGATAACTTGCTGCAGGAGGAGATGCTCACCAGTCGGGTGGTCTAGGGGGTTCTTGGAAAAGAGAAGGCATTTGCTC AAGCCTCGGTTCCCCCATTCTCGCTCTTCTGTCAGCTTGTCTTCCATTAAGTGTGTGTCTCAAGGCCACCCTGCTCAGGACTCCCTGTGAGACGACC TTCTATGCTCGAGTTCATTAAAAACACAATTGCCTGGTGCCCTGCTCTCTCCACTGGCTCAGTTACCTCAAAAGACCAGGGCTAAAGGTGTGATCAC AACTCTATCCCCATTACTGCTCCAACGCAGAGACAGGACTGAGCCGGAGTGAACAAATGAACAAAAATGACTAATAATGCATGCGTGATTAAATACA TAAAAGAGCAGATGACTGGATGAGCAAATCGTTTAAGGAGAGACAGCAAGATCCTAGAATTTTGGAGACTAATTTAAATCCATCTTTGAGATGTATT TGGTCGGAAATTCCTGGGAGGAAAAAAAGTGTAAGTATGAAGAGAGAATAAATGAGAATAGGGGTGGCTTCAGAGAGGTTAACTGCGCGCTGGTCGC TTTTGTACAAGAATGTGAATTGCAGGGAGCAAAATGGGATAGATACTCCCGCCCGAAAGGTGGAATTGAACCACTCTGTCGCTAAACAGCTACAGGT TTGAAGCCTGCACCCCAGACCACTGAGGATCATCCGGGCGAAAGGAGCTATTTTCGGTTAGTTATATAAAGGCCAGATACTACTACTTTTTTCACTT ATGGTCATTATTTGTGGTATACAGTAGATAATTAATTTCAATGGTTTCGAACATTTTTTTTCACTTTTTCTTGTGAACATGTGTTTCCTCAGTAAAG TGTTCCGTGAATGACTCTACTAACTAAAAAGTAAGTAGCTTCATTTGCATAGCGCCTTGCATTCTGGGAAGCAGCGCCTAAAGTGCCTGTCTCCCTA ACTAAAAGCAGAATTTTTTGCAAAGTGAAAAGTCAGTTTTATTTTTGTTTGTTTGTTTGTTTGTTTGTTTTTAATGGAAAAACTTCTCACGCGGCCC ATTCGTAGCAGAATTCGAGATTTTCTGCAAGCGAGACCGTAGGGTCTGACGGCACGCGGCCGCAGAGCGACACCTGCCGTTGCTTTATAGAACTGCA AGTATGTAGGGAATCTACTGAGTCCCTAAGGTGATGGAGTTGACAACCAACTCCCCTTGCGTTTAGACGCTAAAAACCATCCCTTTTTATATCTATG TGATTAGCCCAGGGAAACTAAGGCTCAGACATGGATAATACCACAGCCGAGTTCCTGTAGCCCAACTCCCTAGGGGAAATGAAACCTACAGTTGTGG TTTTAATATGCTTGGCCCAGGGGCAGTGGCCCTATTGGCAGGAGTGGCCTTATTAGAGGAGGTGTACCTTGTTAGAGGAAGTGTGTCACTTGGAGGC GAGGTTTTGAGGTACGTATGCTCAAGTCTGGCCAGTGTGATCCTGGCTGTCTGCAGAACGCGGTCTCCTGGCTGCCTTCGGATCAAGGTGTAGAACT CTCAGCTCCTTCTCCAGCACCATGTCTGCCTGCTTAATGCTTTGCTTCTTTCCATGACGATAATGAACTGTGCCTCTGAAACTGTAAGTCAACCCCA ATTACACAATTACATGTTTTCTTTTATAAGAGTTGCATATATATATATATATGTCACACTCTTTAGCTCTGGCTGGCCTGAAATTCACTATGTAGCC CAGGATTGCCTGAACTTTGAAGCAATCTTCCTGCCTCAGCCTCCCAATGGTATTACAGGCATGAGTCACAACAAGCCATTTAAATCTTATGATGACT TATAAGAAGACAGAAAATCAGAGTTCCTTTACCTAGTTCACAGATCCCTACAATCTAACCTCGTTCGCTCCATAAACAGCCCTACCCCACCCTCCTG GAACTGCTTTGAGGAATGCTGCAGGCTCTCACAGGCACACTCCTCCTTGGTTAATCTCTTCAGCCTGGTTGCCTTCCCTCCCCATGTCCATGTGGCC CAAAGCCTCTCATCCTGTTCTCAAATACCACTAGCTAGTAAGGCCTCCCCGACCTGACCCCGGTTTAAATATTAGAAAAGGGTCACTTTCTCCCCTG CCACAGACAACCAAACCACCATATGCTTGTCACTTACTACCTGACTATGAAGGTGAATAGATGTCTTCACAACCTTTCTCTGAGCCTCAGTTTCCCC ACCTGCATAATGCATCTGAGACACAGAATTCCCTAGAGCTGTGGTTCTCCTCATTCCTAGTGCTGGGACCCTTTAATACATTTCCTCATGTTGTGGT GACTCCACCACCACCATAAAATTATTTTCATTGATACTTCATAACTGTAATTTTTTCTATTCTTATGAATAGTAATGTAAGCATTTGTGTTTCCCAG TGATCTTAGATGACCCTGTGGAAGAGTCATTCCACCCCCAAAGGGGTCCCCACCACAACTTAAGAATTCCTGCCATAGAGGAATCACAAGGAACCAA TGAATTACACTTTGGGTCGACTTTTGGGCTGGCCTCTGGGAGGCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN 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NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTTGGATTACAAACATGTGCCACCAACTCTGGCTGCCCATTATGCATTTCTGTGG CAGGCGTTGATGGCTATTAAACCCAAGCCTTGTATATACTAGGCAAGTACCCATCCACTGAACTACAGCCCTAGCATGGACCTCACAGGGCAATGGC CTGACATCTGGGAAACACTATCACAGAGTATAATAATAAAACCGTAGCATGCTTTTCAGATTGAGCATTTCTGCTGGGTCACACTTGGAAAACCTTC TTATTGTTATCATGAGTATGTGTGCATACATGTGGAGGTGAGAGGATGACGTCATAGAGACAGCTCTGTCTCCCATTCTTTATTGCCAATATTATTT TATGTTTTGTCTGCGTGTATGTTTGTATACCAAAGTGCATGCAGTGCCTGTAGAGACCAAAAGGGGGCATCCCTGAGACTGGAGTTAGAAGTGGCTG TGAACCACTCACTCTGTGGGTGCTGGGAATCAAACCCCGGTTCTCTGGCAGAGCAACTGGTGCTCTTAACCACCGAATCAACTTCTCCAGCCCTGCA TTGCTTTAATCTTTTGGTCGATTCCCCCAATCCAACTCATACCGCCAAGTCTGAGTAGCAAGTGCCTTTATCTGGGAGACTCACTGATCTTATTTTT TTTTCCTTTCTTTTTCTTTCTTTTTTTCTTTTTTTTTTTGAGTCAGGTATGATTATTTAGATGGCCTCGAACTCACAGAGATCCACCTCCCTCTGTT ATGCCAGGCTTTTAAAAAACAACATTTATTTTTGATGCATATATAGGGCTGTGCAAACACAGCCTGAAGGAGTCGTTTCTGATTGGCTCACAACGTG GTTCCAGGGATGGAACGCGGGTGACCAGCTTGAAGGTAGGTGCTTTCACCAGCCCCAAGAATTTATTTTTTAACTTTATTTTTTTAATTAAATGATT AAATGACACATGTTCATTGTGGGTAGTGCAGGTATGCGATGGAGCACATGTAGAGGTGACATTACTGCAGGCGGTCTCTCTACCATGGGGATTCAAC TCAGACCACTGCTTCCTTTACCAGATCATCATTCTTGCATCCCCCAATCATTTCTTTTTGTTGATGGTTTTGTTTGTTTGTTTTAGTTTTGGGGGGT TTTTAAAGTTTTTTTCGAGACAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATTAAAGGCGTGTACTACCACTGCCTGGGCAT AACCGGCCTTTCTGCCTTATTTGTTTCGAAACGGAGTCTCATGTAGCCTGAGGTGGCCTCAAACATGCAATGTAGCTGCAGCTGGGATTACATATGT TCACCACCACAACCTGTTTTATGCACTGCTAAGAGATTAAACCTGGGCCTTCGTGCTAGGTAAGGACTCTATTAACAGAGCTACAACCTCTGCCTGG TTTTTAGTTTTTCAGACAGGGCTTTGCGACATAGCCCTAACTGGCCTTGAACATGCAATGATCCTCCTGCCTCGGCCTCCTGGGTCCTCAGATTGTT GATGCTACACCCACATATCTCAGACCTGAGGGTTGGCAGCTTGGGCCATGCTCTGATTTGGGAGTGACATATTAACAGTAGTTTAATACGAATTTGA ATCCACCTTACTTTTTTGGTGGCACTGACATTGAACTCATGGCCTTCCACAGGCTTTTACGTGAGAAATGTTTTACCTCCCTTCCTTGAGCCATGAG CGAGCCCCTCACTGGTGGAGTCTATGCAGCTGGTCTGAAACTCATACCATCTTCCTGCCCCACTCTCCGAGTGCTGAGTGTCTACAGAGCTCCTGAC TCTGCCTGGGACGTGATGTCTGTGGGACCTTGGCTATAGAAGGGAGGCAGTCACACCACCCATTTTTGGCTTCCATGTCGGCAATGGAGAGCTTGCC ATACTCACCTGATGTTGTCTGTACAGAAGGGGGACGGTAAACAAAGCAACCACTCCTACAGATGCAGAGAGAGAGATGGGGGATGGGGGGTGTCAGG TTCTCCTGGCAAAGGGTCAGCTCCGTTGAGGGCTTTTCCACTCCCGACCAAATTCCCAAAATAACGACTCTGAGACTCAATATTTCATGAACAAATG CTTGGGCTAGCTTGGGCTTGTTCCCTGACAAGCCCCTATCTCATTTAACCCGTTTATTCTATTCTATGAATGCCACATGGCTGGTTACCTCGTCTCA GTTTCATGAGACCCTCTCATCAGCACTAGGGCAAACCCTGATTCTATTACTCTCTTCCTGCAGGAGCTCGGGCCCCCTATTTCCTCCCTAAGCTAAT AGCCCAACAGCTTTTGATTGACAGGTGATGCTTCCACACAGTGCACACGAAGATTCTCTTTACCCTCCATGTGNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATTTTTGTAGAGAGG GCTGAGGTCAAGTTTAAGATTAGGAAAGAGAATCAAGAATTATCAAGGATAAAGGGAGAGGTCAGGATTTACAGGGGAGCAGGGTTCATGGTCAGAA TGAAAATGGATGAGAGAGGGCAATGCGTGAGCTGAGGTCAAGGGTCACAATGGACGGTCCGTCGGCGGGGGCTGGGCAGGGCCAAGCATTCTCACTG GAAAGGGTTGGTGCCGTCGCCCCGGTGCACGGCCTGCAGCACTTTGCGGTAAACCCTGAGAGAGATGGTGGCGCAGAGACCCAACAGGGCCAGGTGC GCAGCCACGGACACGATGCTAAAGTGCAGGAGGCAGAGGAGAGAGGCCATGAGGCCCGTGAAGACCGCTCCCGACGTCCTGGTGTCCTTCCAGTACA ACAGGTCTGCCACTGTGGAAAAGAAGACAATGTTGGGACCCGACCTGACCAAGCTCACTCCCTTTCTGTTTGTTTTTTAGAGATAAGGTCTCACTAT GAAGCTAAGGCTGACTTCAAACTATGAAACCCTGGCTGGTCTTGAACTCCTGATTATTCTAATTCATCCTTTCTTTTTCTTAGACTGAGTTAAGTTT GACCGGCTTCAAACTCAAGACAAATACTCCTGCCTCTACCCTTTAGTGCTTCAAGGAGGTGCTAAGGATCAAATTTAGGGCTTCATGCATGCTAGGT AAAACCCAACTGAGCTACTTCCCTGAC MOUSE SEQUENCE - mRNA ATAAATTCTTATTTTGACACTCACCAAAATAGTCACCTGGAAAACCCGCTTTTTGTGACAAAGTACAGAAGGCTTGGTCACATTTAAATCACTGAGA ACTAGAGAGAAATACTATCGCAAACTGTAATAGACATTACATCCATAAAAGTTTCCCCAGTCCTTATTGTAATATTGCACAGTGCAATTGCTACATG GCAAACTAGTGTAGCATAGAAGTCAAAGCAAAAACAAACCAAAGAAAGGAGCCACAAGAGTAAAACTGTTCAACAGTTAATAGTTCAAACTAAGCCA TTGAATCTATCATTGGGATCGTTAAAATGAATCTTCCTACACCTTGCAGTGTATGATTTAACTTTTACAGAACACAAGCCAAGTTTAAAATCAGCAG TAGAGATATTAAAATGAAAAGGTTTGCTAATAGAGTAACATTAAATACCCTGAAGGAAAAAAAACCTAAATATCAAAATAACTGATTAAAATTCACT TGCAAATTAGCACACGAATATGCAACTTGGAAATCATGCAGTGTTTTATTTAAGAAAACATAAAACAAAACTATTAAAATAGTTTTAGAGGGGGTAA AATCCAGGTCCTCTGCCAGGATGCTAAAATTAGACTTCAGGGGAATTTTGAAGTCTTCAATTTTGAAACCTATTAAAAAGCCCATGATTACAGTTAA TTAAGAGCAGTGCACGCAACAGTGACACGCCTTTAGAGAGCATTACTGTGTATGAACATGTTGGCTGCTACCAGCCACAGTCAATTTAACAAGGCTG CTCAGTCATGAACTTAATACAGAGAGAGCACGCCTAGGCAGCAAGCACAGCTTGCTGGGCCACTTTCCTCCCTGTCGTGACACAATCAATCCGTGTA CTTGGTGTATCTGAAGCGCACGCTGCACCGCGGCACTGCCCGGCGGGTTTCTGGGCGGGGAGCGATCCCCGCGTCGCCCCCCGTGAAACCGACAGAG CCTGGACTTTCAGGAGGTACAGCGGCGGTCTGAAGGGGATCTGGGATCTTGCAGAGGGAACTTGCATCGAAACTTGGGCAGTTCTCCGAACCGGAGA CTAAGCTTCCCCGAGCAGCGCACTTTGGAGACGTGTCCGGTCTACTCCGGACTCGCATCTCATTCCACTCGGCCATAGCCTTGGCTTCCCGGCGACC TCAGCGTGGTCACAGGGGCCCCCCTGTGCCCAGGGAAATGTTTCAAGCTTTTCCCGGAGACTACGACTCCGGCTCCCGGTGTAGCTCATCACCCTCC GCCGAGTCTCAGTACCTGTCTTCGGTGGACTCCTTCGGCAGTCCACCCACCGCCGCCGCCTCCCAGGAGTGCGCCGGTCTCGGGGAAATGCCCGGCT CCTTCGTGCCAACGGTCACCGCAATCACAACCAGCCAGGATCTTCAGTGGCTCGTGCAACCCACCCTCATCTCTTCCATGGCCCAGTCCCAGGGGCA GCCACTGGCCTCCCAGCCTCCAGCTGTTGACCCTTATGACATGCCAGGAACCAGCTACTCAACCCCAGGCCTGAGTGCCTACAGCACTGGCGGGGCA AGCGGAAGTGGTGGGCCTTCAACCAGCACAACCACCAGTGGACCTGTGTCTGCCCGTCCAGCCAGAGCCAGGCCTAGAAGACCCCGAGAAGAGACAC TTACCCCAGAAGAAGAAGAAAAGCGAAGGGTTCGCAGAGAGCGGAACAAGCTGGCTGCAGCTAAGTGCAGGAACCGTCGGAGGGAGCTGACAGATCG ACTTCAGGCGGAAACTGATCAGCTTGAAGAGGAAAAGGCAGAGCTGGAGTCGGAGATCGCCGAGCTGCAAAAAGAGAAGGAACGCCTGGAGTTTGTC CTGGTGGCCCACAAACCGGGCTGCAAGATCCCCTACGAAGAGGGGCCGGGGCCAGGCCCGCTGGCCGAGGTGAGAGATTTGCCAGGGTCAACATCCG CTAAGGAAGACGGCTTCGGCTGGCTGCTGCCGCCCCCTCCACCACCCCCCCTGCCCTTCCAGAGCAGCCGAGACGCACCCCCCAACCTGACGGCTTC TCTCTTTACACACAGTGAAGTTCAAGTCCTCGGCGACCCCTTCCCCGTTGTTAGCCCTTCGTACACTTCCTCGTTTGTCCTCACCTGCCCGGAGGTC TCCGCGTTCGCCGGCGCCCAACGCACCAGCGGCAGCGAGCAGCCGTCCGACCCGCTGAACTCGCCCTCCCTTCTTGCTCTGTAAACTCTTTAGACAA ACAAAACAAACAAACCCGCAAGGAACAAGGAGGAGGAAGATGAGGAGGAGAGGGGAGGAAGCAGTCCGGGGGTGTGTGTGTGGACCCTTTGACTCTT CTGTCTGACCACCTGCCGCCTCTGCCATCGGACATGACGGAAGGACCTCCTTTGTGTTTTGTGCTCCGTCTCTGGTTTTCTGTGCCCCGGCGAGACC GGAGAGCTGGTGACTTTGGGGACAGGGGGTGGGGCGGGGATGGACACCCCTCCTGCATATCTTTGTCCTGTTACTTCAACCCAACTTCTGGGGATAG ATGGCTGGCTGGGTGGGTAGGGTGGGGTGCAACGCCCACCTTTGGCGTCTTGCGTGAGGCTGGAGGGGAAAGGGTGCTGAGTGTGGGGTGCAGGGTG GGTTGAGGTCGAGCTGGCATGCACCTCCAGAGAGACCCAACGAGGAAATGACAGCACCGTCCTGTCCTTCTTTTCCCCCACCCACCCATCCACCCTC AAGGGTGCAGGGTGACCAAGATAGCTCTGTTTTGCTCCCTCGGGCCTTAGCTGATTAACTTAACATTTCCAAGAGGTTACAACCTCCTCCTGGACGA ATTGAGCCCCCGACTGAGGGAAGTCGATGCCCCCTTTGGGAGTCTGCTAACCCCACTTCCCGCTGATTCCAAAATGTGAACCCCTATCTGACTGCTC AGTCTTTCCCTCCTGGGAAAACTGGCTCAGGTTGGATTTTTTTCCTCGTCTGCTACAGAGCCCCCTCCCAACTCAGGCCCGCTCCCACCCCTGTGCA GTATTATGCTATGTCCCTCTCACCCTCACCCCCACCCCAGGCGCCCTTGGCCGTCCTCGTTGGGCCTTACTGGTTTTGGGCAGCAGGGGGCGCTGCG ACGCCCATCTTGCTGGAGCGCTTTATACTGTGAATGAGTGGTCGGATTGCTGGGTGCGCCGGATGGGATTGACCCCCAGCCCTCCAAAACTTTCCCT GGGCCTCCCCTTCTTCCACTTGCTTCCTCCCTCCCCTTGACAGGGAGTTAGACTCGAAAGGATGACCACGACGCATCCCGGTGGCCTTCTTGCTCAG GCCCCAGACTTTTTCTCTTTAAGTCCTTCGCCTTCCCCAGCCTAGGACGCCAACTTCTCCCCACCCTGGGAGCCCCGCATCCTCTCACAGAGGTCGA GGCAATTTTCAGAGAAGTTTTCAGGGCTGAGGCTTTGGCTCCCCTATCCTCGATATTTGAATCCCCAAATATTTTTGGACTAGCATACTTAAGAGGG GGCTGAGTTCCCACTATCCCACTCCATCCAATTCCTTCAGTCCCAAAGACGAGTTCTGTCCCTTCCCTCCAGCTTTCACCTCGTGAGAATCCCACGA GTCAGATTTCTATTTTTTAATATTGGGGAGATGGGCCCTACCGCCCGTCCCCCGTGCTGCATGGAACATTCCATACCCTGTCCTGGGCCCTAGGTTC CAAACCTAATCCCAAACCCCACCCCCAGCTATTTATCCCTTTCCTGGTTCCCAAAAAGCACTTATATCTATTATGTATAAATAAATATATTATATAT GAGTGTGCGTGTGTGTGCGTGTGCGTGCGTGCGTGCGTGCGTGCGAGCTTCCTTGTTTTCAAGTGTGCTGTGGAGTTCAAAATCGCTTCTGGGGATT TGAGTCAGACTTTCTGGCTGTCCCTTTTTGTCACCTTTTTGTTGTTGTCTCGGCTCCTCTGGCTGTTGGAGACAGTCCCGGCCTCTCCCTTTATCCT TTCTCAAGTCTGTCTCGCTCAGACCACTTCCAACATGTCTCCACTCTCAATGACTCTGATCTCCGGTNTGTCTGTTAATTCTGGATTTGTCGGGGAC ATGCAATTTTACTTCTGTAAGTAAGTGTGACTGGGTGGTAGATTTTTTACAATCTATATCGTTGAGAATTC MOUSE SEQUENCE - CODING ATGTTTCAAGCTTTTCCCGGAGACTACGACTCCGGCTCCCGGTGTAGCTCATCACCCTCCGCCGAGTCTCAGTACCTGTCTTCGGTGGACTCCTTCG GCAGTCCACCCACCGCCGCCGCCTCCCAGGAGTGCGCCGGTCTCGGGGAAATGCCCGGCTCCTTCGTGCCAACGGTCACCGCAATCACAACCAGCCA GGATCTTCAGTGGCTCGTGCAACCCACCCTCATCTCTTCCATGGCCCAGTCCCAGGGGCAGCCACTGGCCTCCCAGCCTCCAGCTGTTGACCCTTAT GACATGCCAGGAACCAGCTACTCAACCCCAGGCCTGAGTGCCTACAGCACTGGCGGGGCAAGCGGAAGTGGTGGGCCTTCAACCAGCACAACCACCA GTGGACCTGTGTCTGCCCGTCCAGCCAGAGCCAGGCCTAGAAGACCCCGAGAAGAGACACTTACCCCAGAAGAAGAAGAAAAGCGAAGGGTTCGCAG AGAGCGGAACAAGCTGGCTGCAGCTAAGTGCAGGAACCGTCGGAGGGAGCTGACAGATCGACTTCAGGCGGAAACTGATCAGCTTGAAGAGGAAAAG GCAGAGCTGGAGTCGGAGATCGCCGAGCTGCAAAAAGAGAAGGAACGCCTGGAGTTTGTCCTGGTGGCCCACAAACCGGGCTGCAAGATCCCCTACG AAGAGGGGCCGGGGCCAGGCCCGCTGGCCGAGGTGAGAGATTTGCCAGGGTCAACATCCGCTAAGGAAGACGGCTTCGGCTGGCTGCTGCCGCCCCC TCCACCACCCCCCCTGCCCTTCCAGAGCAGCCGAGACGCACCCCCCAACCTGACGGCTTCTCTCTTTACACACAGTGAAGTTCAAGTCCTCGGCGAC CCCTTCCCCGTTGTTAGCCCTTCGTACACTTCCTCGTTTGTCCTCACCTGCCCGGAGGTCTCCGCGTTCGCCGGCGCCCAACGCACCAGCGGCAGCG AGCAGCCGTCCGACCCGCTGAACTCGCCCTCCCTTCTTGCTCTGTAA HUMAN SEQUENCE - GENOMIC CACTAAGCACTCTCACCACCCAATGCCTGGAGTGGTTGTAGTCAGTGAGTGACACATTGCACAGTGTGTGCCCCCTGGATTGGGGGTGGGTGAGAGA CAGCCCCCACAGTGAGTGGCACCCCTGGCCAGGGCCTGGGACAAGTCTGTATCCAAGGGTGGCTCTCTGCTTAGGTCTGTGTTTGTACCTGGGTGTG TCTGTGTCTGCCCTACTCTGTGCATACTCATATATGTGAACCCGTGTGTGTGTGTGTAGTTGTGAGTGTGTGTGGAAGAGGCTGCATGGCAGTGGAA GCTAGGTGTGTGATTCGTGTATCTGTGTGCCTAGAGTGCCTTGTTCTATAGATTTGGATGCCACTCCAAGCAAGTCAGTGGGTCTTTTTGTTTTTTG TTTTTTGAGATGGAATCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTTGGCTCACTGCAACCTCTACCTCCTGGGTTCAAGTGATTCT CCTGCCTCGGCCCCCCGAGTAGCTGGGATTACAGGTGCCCACCAATACACTCAGCTAATTTGTTGTATTTTTAGTAAAGATGGGGTTTCACCATGTT GGCCAGGCTGGTCTCAAACTCCTGACCTCATGATTCTCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCAAGT CAGTGGGTCTTTAGGAGCTGTTTCGTACGGTGTGACTGTGAGTGAACCTTCGCACACGTGTCTGTACGGATATCTAAGAAATICTTCAAGTAGGCCG GGCACAGTGGTTCAGGCCTGTAGCCTTAGCACTTTGGGAGGCCCAGGTGAGTGGATCGCTTGAGCTCAGGAGTTCGAGAACAGCCTGGGCAACATAG TGAGACTTCGTATCTATAAAAAATATGAAAATTAGCCAGGCATGACAGTGGGCACCTGTAGTCCCAGCTACTACTTGGGGGGCTGAGGCAGGAGGAT CCCTTGAGCCTGGGAGGTGGAGGCTGCAGTGAGCTGAGATCGAGCCACTGCACTCCAGCCTGGGCGACAGAGGGAGACCCTGTCTCAAAAAAAAAGA AAAGAAAAGAAAAAAAGAAGACATTCTTCAAGTCCACAACTCTGAGGGTATCACTGTGAGAGCAGGGGTCCTAGCTCTACCCATTTGTGTGTGTGTG GAGATGTGTAAGTCTATGTAGACAAAAGTGTGTGTCATTTACTGTGTTTGGGGTGTGAACACCTATGTGATGTGTTTGCACAACTGCACGTGTTTTG TTCTGTGTGTGTGATCGTGTGTTCAAATAAGTCATCTTGTCGCCGGGCGTGGTCGCTCATGCCTATAATCCCAGCACTTTGGGAGGCCTAGGCAGGA GGACCATTGAGCCCAGGAGGTCCAGACTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGCAAGACCTTGTCTCAAAACAAAAG CAAAAACAAAAATAAACAAATAGTCATCAGGTGCCTGCACAGACAAAGGTGAAAGGTGTCTGCCTGTTGAGATCTGTGGATAGGGTGTATATATGGA CATCTCAGCCTGTCTACGTGTGTATCTGTCTCTGTCCTCACGGCAAAAGAGAGGTTGGCCGGGTGTGTGGTGGCTCACGCCTGTAATCCCAGCACTT TGGGAGGCTGAGGCGGGCGGATCACCTGAGGTGAGGAGTTCAAAACCAGCCTGGCCAACATGGCGAAACTCCATCTCTTCTAAAAATACAAAAAAAT TAACCGGGCGTGGTGGCACACGCTTGTAATCCCAGCTACTCAGGGAGGCTGAGGCATTAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGC CAAGATTGCGCCACTGGACTCCAGCCTGGGCAACAGAACAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAGAGGCTCAGATATGTTTCTGTC TGAGAGTCTGTCAGAGTTTAGGAATTAGTAAATGAATGAATGGTGAAGATCCATTTACTCAACAAACATTTATTTATTTATTTATTTATTGAGACAG AGTCTCGCTCTGTCACCCAGGATGGAGTGCAGTGGCGCAATCTCGGCTCACTGAAGCCTCTGCCTCCTGGGTTTAAGAGAGTCTTGTGCCTCAGCCA CCAAGTAGCTGGGATTACAGGTGTGTGCCACTGCGCCCAGCTAATTTTTGTATATTTAGTAGAGATGGGGTTTCACCATGTTGCCCAGGCTGGTCTC GAACTCCTGGCCTGAAGTGATCTGCTCACCTCAGTCTCCCAATATGCTGGGATTACAGGCATGAGCCACCAGTCCTGCCTCATTTATTCTTATATTA TATTATATTGTTTTTATTTTAAATTTTTTTGTAGTGACAGGGTCTTACTATGTTGACTGGGCTGGCCTCAAACTGGCCTCAAGTGATTCTCCTGCCT CAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCTGGCTTGAACAAATATTTAATAACCACCTATTGGGTACCACGTGCTATGCTGG GGACAAGGCAGTGACCGGGATGGTTTTGGCCGAGCTTTCACCCAGCTCACAACCCAATGAGGGAGACAAACCTATCCCCAGACAATGATGAGCCCAG ATTGGCAGAGTTGGAGGGAGGGACCCCAGGAGAGGGGGCCTTGACTCAGCCTGGAGATCAGGGAGGGCTTCCTGGAGGAGAGGTTATGGGAGTTAAG ACTTGGAGGAAAAGACTATGAGCCACAGGAAGCGAAGGGAAGAGTGACCCAGGCAGAGGGAAAAGCACCTGCAAAGGCCTGAAGTCCAGGGAGAGAG GCCAGGCATCTGGAACACAACGGGGAGAGGAGAGACGAGACTAGGGCACCCTCGGAGCAGGTCGTTCAGGGCCTCAGGAGCCATGGGGAGGAGTATA ATGCAGGATGCAGGGGTACTGGGAGGGTCAAGCTAACAGTGTCCAATCTGGGTTACTCTGCTTCCCTGAAACTCCAGGGACATCTCCTCCAGGAAGC CCTAGGGATTGCTCAGTGTGGAGCGGCTCAGCCACCCAGTCACACTCACTATTCAATGCTGAGCACTGAGGAGGCAGCCGTTACTAAATCAGCCTGG ATTTGCCCTCCCAGAGGTCACAGTCACAACAGTCAAACACACACCTGCACGTGCACACTCATGAACGTGCCCCTCCCCTCCTCTGGAGCCTCAGAAA CCCACAGACCTTGTTCCTCCCAGGGGGTGTCCCTGGGGCCAAAGCTTCTGCACTACCAGGGGGCTTGTTGGAAATGCAAAAGATGGCTGGGCACAGT GGCTCACACCTGTAATCCCAGCAGTTTGGGAAGCTGAGGCAGGCAGATCATTTGAGGTCAGGAGTTCATTTGAGGTTGGGAGTTCAAGACCAGCTTG GCCAACATAGCGAAACTCTGTCTCTACTAAAAATACAAAAAAATTAGCCGGGCGTGGTAGCACACGCCTGTAATCCCAGCTACTTGGGAGGCTGAGG CAGGAGAATCTTTTGAACCCGAGAGGTGAAGGCTGCAGTGAGCCAAGATGGCACCACTGCACTCCAGCCTGGGTGACAGAGTGAGTCTTAAAAAAAT AATAATAAAATAGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCACCACTTTGGGAGGCTGAGGCAGGCGGATCACCTGAGGTCAGGAGTTCGAGAC CAGCCTGACCAAAATAGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTTAGCTGCGCGTAGTGGCTAACGCCTGTAATCCGAGCTACAGGCTG AGGCAGGAAAATTGCTTGAACCCAGGGGTGCAGAGGTTGCAGTGAGCCAAGATGGCACCATTGCACTCCAGCCTGGGCAACAACAGTGAAACTCCGT CTCAAAAAACAAAATACAAAAATTAGCCAGGCATGGTGGCACACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCG GGAGGCAGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCAAGCCTGTGTAACAAGAGTGAAATTCCGTCTCAAAATAAAATAAAATAATAAAA ATAAAAAGATGACCACAGCAGATCTGCTGGCTCTCCAGGCAATTCGTGATCACCACGAATTGAGAAGCGCTGCTCTCAGGCTTAACCCCCCTGTACC TCAGTTTCCTTTTCTGTACAAGGAGATCAAAACAGAATCCATGTAGAGGACTGACGTGGAGTGAGGCTTAACTGAGATAATGAGTGTGAAAGTGCTA AGCACAGCTTCCTAAGTGCTTGTTTTCAGCAGCTCCTCTTCCTCTTTTCTATTTTTTTATTTTTATTTTTTTTGGGGGGGGAACAGGGTCTCGCTCT GTTGCCCAGGCTGGAGTATAGTGGCAGAGTCATAGCTCACTGCAACCTCAATCTCTCAGGGCTCAAGTGATGCCCGTGCCTCAGCCTCCTGAGTGGC TGGGACTACAGGTGTGTGCCACCATGCCCAGCTAATTTTTAAATTTCTTGTAGAGGTTGGGGGTGGGTCTCACTATGTTGCCCAGGCTGGTCTTGTA CTCCTGGCCTCTGGCGATCCTCTTACCTAGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCCCTCCTCCTCCTCTGTATTAT TAAATTTCAGAGCTGGAAAGAAATTTCGAAGACCGCCATCACTCAACCTTCTTGCTCTACAGATGGGGGAACTGAGGAACAGAGGAGCAGAGGTTTG GCCAGAGGAAGGTGGGAAGGACGTGGTGTGGCTGGCCTTCACAGACTCTGCCGGGGGCTGTTTACAGGATACTCTGAGGAAAGCCAGGATGGGCACT GATACCCACCTCCACCCTGCGGGAGGCAGAAGGCTAAGGCTCCCCCAGCCGTCTCCCCCAAGCAGAGCTGAGCCCTTGGGAGCCAGGGCAGAGATGC AACCCTCTCCGCCATGCTCAGGTCCTCCTCCTCCTGGAAGCTCTCCTTCCAAGAGGAGCCTCTTATTTTATTTTTTATTATTATTATTTTTGAGACA AGGTCTCACTTTGTCACCCAGGCTGGAAGTGCCGTGGCATGATCATGGCTCACTGAAGCCTTGCCCTCCCCAAGCTCAAGTGATCCTCTCACCTCAG CCTCCCAAATAGCTGAGACTACAGGCACACGCCACCACCCCTGGCTAGTTTTTGTATTTTTAGTAGAGATGGGGTCTTGCCATTGTCCAGGCTGGTC TTGAACTCCCGGGCTCAAGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGACACTGAGCCTGGCAAGGAATGAGCCTTAT GGAGAAGAACTTGATTTACCCACTCCATGCTCTGCAGGCAGGTGTGTCATGTCTGTGAGTGCAGGTGTGTGTGTGTGTGTGTATGTGTGTGTGTGTG TGTCTCCAGGGCCAATTTCTCCCTTAGGCCCAGGGGCACAGTGCCTAGGGCCCATGATAAATTTAACCGACCCACGGATATGGGTCAGGAGGGTATA CATGTATAAAGTTCAGGAAGACTTTGTTTTAGTAACAAAACGAGCATGTACAATCTGTCAGGAGCCTTATGATATCTTCCCACCAGTCTCATGAGTG GGCACTACATCTTGTTCTCCTTTGTCGGGTAGGGAAACTGAGGCCCCGGATGTCCTAGCTCAAGTTCACCAAGCTACTTGGTGATAGAAGCGGAACA TAAGCCTAGGCCACCTAGCTTCTGGGTCTGCGATCGTGTGAGGATAAATGCCCAGTGTGTTCGTGAACATGAGCATCCCTGTGTGAATAAATTGACA TACATAAACCCATTTAATAAATTTCAAAGCCAGGCGCCGTGGCTTACTCCTGCAATCTCAGCGCTCTGGGAGGCTGAGGTGGGAGGATCGCTTGAAG CCAGGAGTTTGAGATCAGCCTGCAACAAAGTGAGACCCTGACTCTAAAAACATTTTTTTGAATAAAAAAATTAGGCTGGACACAGTGGCTCACGCCT GTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGTCAACAGGGTGAAACCCTTTCTCTACTA AAAATAGAAAAATTAGCCAGGCGTGGTGGCACATGCCTGTAATCCCACCTACTGGGGAGGCTGAGGCCGGAAAATTGCTTGAATCTGGGAGGTAGAG GTTGCAGTGAGCCAAGATCATGCCATTGCACTCCAGCCTGGGCGAAGAAACGAGACTCTGTCTCAAAAAAAAAAAAAAAAAATTAGTCAAGCATGGT GGTACGCACCTGTAGTTGTTAGTTACTTGGGAGGCTGAAGCAGGAGGATTACTTGAGGCCAGGAGTTCGAGGTTACAGTGAACTATGATTGCATCAC TGCACTCTAGCCTGGATGACAGAGCAAGATCCTATCTCAAAATAATACTAATAGTTCAAGGAACAGACTTTGAAGCCTGACACCCTGCATGGTGTTA TTCCAGCTTTGCTACTTACTTGCTGTGTGACTCTGGGTGAATAACTTAACCTCTCTGGGCTTCTGTTTCCCTTCCTGTAAAATGATCATTTGTACCT CACAGGAGTGTTGTGAGAATTAAATAAGTTAATATAAGCTCTTGGGAAGAATTAGCTCTTGTTATGGTTGTGTGAAGAGCTTTACACGAGTCCCTCT GCAGGATGCATGGTTGTTGGTCTGTGTGTGTGTATATATATATATGTGTGTGTGTATGTGTGTATCTATGTGTATATGTGTATATGTGTGTGTTGCT CTCTTGATCTCTGAGTGTTGTGTGTGTGTCAATGTGTGAGATCATATATGCACCTTTAGTAAAGATCTAGGGGTCTCTGTGTGTTTTGGGGGTCTGT ACCTGTCCTTGGCTGTACACCTGAACCCTACGTCTTCTTGTGTGTGTAGGGATGTGTGTCATGTGTGTTGATAACCATATGACAGTGTGTGTTTCCA CATGCCAGTGTGTGTCTGTGAAGCTGTTTCTATGTGGCTGTGGGTGATTGCCCACGCGTGACCTGGTGAGCGGCTGTGTGGAAGTCTGTGTTGCCTG TGTCGGGTGTGGAGTCTCTGGCCAGCCAGGGTAGGTCTTTGCATGTTTCCTTTATTCCATGGAGGAGGAGATGAGGGGCTTGGATGAGACAGAAGAA TGAGGGGTCACTCCCTGTCTGATGCTGGGGCCGAGTCACTGCCTACTAGTGGCTGCTGTGTCATCTCCCAGTCTCTGTCCCTCCCTCCTGGCTGGTG GCAGACAGAGGGGGCGTGGAGGAACAGGGCAGGGGGTGGGCTTGAGGCTGGACTTTTGTCTGGAAACTTGAACCTCCACCTATGCCCCCCACGTCCC TCTAGTCTTCCACATCTCCCTACACCCTCCCTACTATTGGGGCAGGGAATCAGGACTCCCTGAAAATTAAGAACCATCGCCTTGGCTCTGCCACAGG CTTGCTGTGTAGCCCGGAGACAGGCCCTGCCCCTCTCTCAACCTGTGAAATTCAATGTTTTAAAAGTGCTTCTTCCTTTGTGCCCAGGGCTGGGCCA GGCTGTGCACTGGGAGGGAAGTGCTGGGTTCTCTGAGGTTTGTGAAATAGCTGGTAGCACCCTTCCCAGTGGGTGCTTAAGAGTTGGGGGCTGTAGC ATCTGAAATACCCAAGTCAGTGCAGGCATAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGACCGAGGCAGGCGGATCACCTGAGGTTGGGAGT TCGAAACCAGCCTGGCCAACATGGTGAAACCCCCATCTCTATTAAAAATACAAAAGTTAGGCCGGGCACAGTGGCTTACGCCTGTAATCCCAGCATT TAAGAAGGCCAAGGCGGGAGGATCACCTGAGTTTGGGAGTTTGAGAGCAGCCTGACCAATATGGAGAAACTCTGTCTCTACTAAAAATACAAAAAAA CTAGCCAGGCATGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAAGCACTTCAACCCGGGAGGCGGAGGTTGCGGTGAGC CGAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCTGTCTCAAAAAACAAAACAGAACAAAACAAAAATTAGCCAGGTGTGGTGG CGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGATGTAGGCTGCAGTGAGCCGAGATTGTGGCACTGC ACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCAAAAAAAAAAAAAAAAAACGTCAGATTCATGAACCCCATTTGCTAAGAAGATTTGCTCAGGTAG TCACCTGTACCCCTGTGAGCCAAGATTGCAACAGTACATGCTAAGAGCAGTAAGAAGGAGTTTGTAAAGCTTAGAAAGACCTGACAGGCCAGGCGCT GTGGCTCACGCCTGTAATCTCGACACTTCGGGAGGCCGAGGCAGGCGGATCACCAGGTCAGGAGTTCAAGACCATCCTGACCAATATGGTGAAACCC CGTCTGTACTAAACATATAAAAATTAGCTTGACGTGGTGGCCCGCGCCTGTAGTCCAGCAACTCGAGAGGCTAAGGTGAGGCGGAGGTTGCAGTGAG CCGAGATCGCCACTGCACTCCAGCCTGGCGGCAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAGACCTGACAAGTGAAAGCT ACTAATATTGCCATTATCATTTAAAAAAACCCCAGACACAGGTTTTTCAGGGAGTTTCATCCAACCAGGCAGGTCTCAGAAATCAGAAAAGAAATGG AAAGGGTAGGAAATCTGGAGTTTGACAATTCTGAGTTTGAATTTCTTGTGATGGGATCTTGGGCAAGTCATTTAACCTCCCTGAGTATCATTTTTTT CTTTTATAAAATGAAGATTTTTCTCTCTTAACCTTCCAGAGCTGTTTTAAGGATTACAAATCTTCTACTGAAAGGCGTAGCACAGGAGCTGTGCTTG GCAAGTGCCAAATACAAGGCATTAATTATTATTATTAGAATTAATAATAATATCCCCTCCCTCTTACACAT1CTTTGTCTCCGGGTGGATTAAAAGG TGGAAGGAGAGGCTACCAACACCATCAGAAGAGAGGCTTCTCTCTAAGTTTCATTTCCCATCTCCTCCAAATCCGCATCCCTCCCAAACGCCGGACC TGTAAGGCCAGCAGGGTCCAAGACACACATCCTTTGCCCAGCGGGGAAGATTAAAGCTAAAGCTCAGAGAGGGAAAACATTTCCTAAGCTCGCACAG CGAATCAGGACAGAAACCAGGACGAGCCTCGGAATCCCTCCATTACCTCCACTTTCACCTGAGCATCACAGCCCGCTCGGGACTCAGTTTCCCCACC TACGTGACCACACCACACTAATCAGGGTCTCCTTTTGGAGATCTGCTCTTCTTCTCGAATGGGGGCGCTGCACCATCGGTAGAACAGGGTAGGTGGG GGCGCCAGAGGTGAAGGGGACCTGCAGGCTGGGGTCTTCCCCGCCCGGGTCAGCGGGGTCCCTGCGGGGCTAGTCTAAGCGCCTATTATTACCAGCC CCCGGGGCGGCGTTGCACTGCGCAGGCGCGGGCGGGGCGCGGGCGCGCGCGCGAGCGAGCGAGGGATTCCCTCTGACGTCATTGCTAGGATACCAAA CAAACACTCCGCCGCGCCGGCCGAGCTCCTTATATGGCTAATTGCGTCACAGGAACTCCGGGAAGGCGGGGCCGGGATCCCCTCCCGCCGAGTGGCC CGGAACGCAACCCCCGAGACCCCCAGGGCCCCGAGGGTCATGCAAGTGACCAGATCGAGTCTAGAACAGACCTCTTGCTGGACAGTGCGGGACTCGA TTTGGCGGGGCCGCAGATTTGGGGAAGTTTGTCCAGCAAGGGGCGGGTGACGTAAGCAGGGGGGCGGGTCCCGGGCATATAAATACAGGCTGGCGGG TCTGTGCTTCATTCATAAGACTCAGAGCTACGGCCACGGCAGGGACACGCGGAACCAAGACTTGGAAACTTGATTGTTGTGGTTCTTCTTGGGGGTT ATGAAATTTCATTAATCTTTTTTTTTCCGGGGAGAAAGTTTTTGGAAAGATTCTTCCAGATATTTCTTCATTTTCTTTTGGAGGACCGACTTACTTT TTTTGGTCTTCTTTATTACTCCCCTCCCCCCGTGGGACCCGCCGGACGCGTGGAGGAGACCGTAGCTGAAGCTGATTCTGTACAGCGGGACAGCGCT TTCTGCCCCTGGGGGAGCAACCCCTCCCTCGCCCCTGGGTCCTACGGAGCCTGCACTTTCAAGAGGTACAGCGGCATCCTGTGGGGGCCTGGGCACC GCAGGAAGACTGCACAGAAACTTTGCCATTGTTGGAACGGGACGTTGCTCCTTCCCCGAGCTTCCCCGGACAGCGTACTTTGAGGACTCGCTCAGCT CACCGGGGACTCCCACGGCTCACCCCGGACTTGCACCTTACTTCCCCAACCCGGCCATAGCCTTGGCTTCCCGGCGACCTCAGCGTGGTCACAGGGG CCCCCCTGTGCCCAGGGAAATGTTTCAGGCTTTCCCCGGAGACTACGACTCCGGCTCCCGGTGCAGCTCCTCACCCTCTGCCGAGTCTCAATATCTG TCTTCGGTGGACTCCTTCGGCAGTCCACCCACCGCCGCCGCCTCCCAGGTAAGTTTTTGATAGTAGGGGTGCTGCTTTGTAGGTTTTATTTTTTAAG TCAAGGGTGAAAAGAATAAACCCCAACCCCCACAAAAAGGCGCATCAGAACCCTAGATCTGAGATGGAAAAGGCTCACAGCGCACTTTGCAAACTGC AAAGAGTCGGGAGATGTTTGCAATTGGTTGCGTGCGTGGAGCGCAAGGAGGGAACGCGGCAGGGAGGGTAGGCTTTGGGGCGAGGTGGGGGTGGGGT GGGTAATGCGCTGCTCAATGCAACGTGTATGCGGTAGCGGGGCTGAGAACTTTGAGCCGGCCCCGGGACTGCCCCCTGCTCGGGTCCCAGACCTGAA GCTAGCGCAGTTAGGCAGGTGGGGGAAATCCCGGGGAAGCTTCCAGCAGTCTCTTTTCCTTTCCTCCTCCTTCGGAGCGCCCACTTCGGTGCCGGGT CGCCCTCCACCCATCGGGAAGAGGGGCCTCGAACCCTCAGCCGCGCTGCCTCCGCCTCCTGCGCGGAGACGTAACGGGGGACCCGTGCGTAACGGCT GACGCGCTGGAATCCTCCGTCTGACGCGGGGCACGCACGGCGCGCGGCGCCCCCTTCGTCCGCCCCGCCCCTGACGTCCCGGGAGCGTTCTATTTTG GAACGCCGGGGCCACGTTGCTAAGGGAGGGGGCAGCCCGGCGTTTCGATTGGCCGCCGGGGCGCACGCCTTGGCCAATCAGCTTTCCCTTCCTATTT GTAGGGTGCATTTTCCTTCCCCCCTCTCTGTCCCCGGAACCCGTGGTTCCTTGGCGGCTGGGTCTCTTTTCGGCGCCTCTAGAGGCAGAGGGAGGGG ATCCCTGTCGTGACAAGAGCGCCTGTCTGCGACCCAATGGATCTGCGAGGCCCTTGCGGGGATCTAGTCCCTGGGCTCTCAGGAGAAGGGGGTGTCT GCTTGTGTGCTGGCGTTTCTTGGAGAGATACGGTGGCTGTCACCCTCTTCTCCAGGCACACACAGACACATTCCCACTCCCTCTGCTCCTCATGCCC GGTTCCTCCGGTGTGTCCCAAGACAGGACTAGAACCGCGAACCGAAGGGCAACCAGCCAGGTGGTCTCCAGGAGCTCCGCCCCCTCTGGGTTCCCAG GACTCTGATTGGTCGGCGAGCCAGCCCTTCCCTCACCACGCCCCCCGAGAGAGTAGTTAAGCCTTCAGAGCAGTTCCAGGAGTCCATTTACGGGAGG GGGGAGATGAGCGCTGCTGAGGCTTGGGGGCTCAGGTCCCGCACCATTCCCCCTCCGCGACAATCTGAGAGAGCTCCAGTGGTTACTTTTATCTACC TGTCCGTTCACCCTAAACTGTCACTCGTCAGTCTCACTCTGAGAAGAGACAGTAACTTGAAACGTTGTTCTAAACTCCTAGGCCCGTCCCCCAAACA CCCTTTTGACTGGGACCCCCGCCCCTGCATGGCACCTCGCGCAGAGGGGGGTGTGTATGTGTGTGAGTGTAGAGGAAGGCTTGGCCTAAGGCCTCTC CTTCTCCCTCCCCTTGCCTCTGGGGTGGGGGTGGGGTGTTGTGGCTGTGTGTGTGGCTGTGGCTCCGTCCCGGGGGTTCTGTCACCCGGCTGTGTCC AGCCTCCTCTCCACCCCCCATACCTAAGAGTCACCAACCCGGGGTGTGATTCACCACCCGCTGGAACCGTGCAACCTTTCCCCGAGGAAGAAGGAGG AGGTAGAAGCCAGTTGAGCAGAAATCCTCTCATTAACCACTGCGTCACGGTGTAGTGGAAGGGTGGGTGTTGTGGCTTTTTCCCTGTGACACACACA TCCACACTCGCTCACCCTGTGCTCACTCACGGGGTCGGTGTGTGTTATGTGTGTTGGGTGTGTGTGTGTCGGTGTCTTTGTTTGTGTGTCTACGCCT GTGTGTGTATGTGTCACCCCGTAGGAGTGCGCCGGTCTCGGGGAAATGCCCGGTTCCTTCGTGCCCACGGTCACCGCGATCACAACCAGCCAGGACC TCCAGTGGCTTGTGCAACCCACCCTCATCTCTTCCATGGCCCAGTCCCAGGGGCAGCCACTGGCCTCCCAGCCCCCGGTCGTCGACCCCTACGACAT GCCGGGAACCAGCTACTCCACACCAGGCATGAGTGGCTACAGCAGTGGCGGAGCGAGTGGCAGTGGTGGGCCTTCCACCAGCGGAACTACCAGTGGG CCTGGGCCTGCCCGCCCAGCCCGAGCCCGGCCTAGGAGACCCCGAGAGGAGACGGTGAGTAAGGGACATCAGAACTTGGCCTGGGTAGGGGGAAGCA AGAGAGGCAGGAAGTTTCTTATGAATGGAGGGGGGCTCCACTAAGGCCTCAGTGTTACAGAAACCCCAAGATCCTTGCTACACGAGCGAGGACCGGA GGCTTGTTTTTTGGCTCTTGGGGGTTCTGAAAGAAGTAGAGGTTCGGGATGGGTGGAGGAGTGCTGTATCCCCAAATCTCATGGCCTCTATCTCCCT GACTCAGCTCACCCCAGAGGAAGAGGAGAAGCGAAGGGTGCGCCGGGAACGAAATAAACTAGCAGCAGCTAAATGCAGGAACCGGCGGAGGGAGCTG ACCGACCGACTCCAGGCGGTGAGGACAGGCCCTGGGGTGGGAGAGGGGATGTTGAGGGGAGCTCTCTCCCCATTCTCTGCCCCCTCTCCACCTGTAC CCTTATCCTGGGTTGAGAACTAGACGTTCCACACATGGAACTAGGTACTGCTGTGGCCAGACTGGGTAGCCCAGGGCACAAACACAGACCCCCATGG ACTTAAGTCAACTCCTGGTCCCCCCCCCATTTCCTGACCCCACGGACTACTCTCCTAGCCTTCATTTCATCCCAAGGGGCCACATGGGGCCCTTGAG GAGAGGGGCGCCCCCATCATTTCTCCCATCTGGTCTTCAGCAAGTAACAACCCATTTTGCCTCAGTTTCTCCATCTCTGCAAACCCTCATCAAATCT CCCGGGCTCTTTCTACCCTTAACACTCTGGAAAGCCTGTGAAATGAAATTATTCCACCTCCTGCCCTAGCCACCCACAGCTCTCCTGGTGCTGGTGG CATCCCCCAAAACCCACTCCCTTCCTACGTCCTCCCTTGGTCTGAGAGTTCCCTGCTGTATGCCTGCAGGGTGAGCTGTTACTCCTTGAGGGAACAA GGGAATTGTCAACTTTCCTTCTCTACTTTTTCTCTTCCCCGGGAGGTAGAGAGGGAGGGGTAATAGAAGGGAACACATTAAAAACACATAACAGTGG CTCATGCCTGTGATCCCAGCACTTTGAGAGGCCAAGGCAGGAGGATTGCTTGAGCCCAGGAGTTTGAGACCAGCCTGGGAAACATAGGGAGGACTTG TCTCTACCAAGAAAAAAAAAAATTAGTTGGGCATGGTGGTGCACACCACTGTGGTCCCAGCTACTATGGAGGCTTTAGTGGGAGGATCGCTTGAGCC GAGGAGGTCCAGGCTGCAGTGAGCCATGATTGCACTATTGCACTCCAGCCTGGGGGACAGAGCGAGACTCTGGCTCAAAAGCAAAACAAAACCAACC ACATAACGATTGTTCATTCATTCAACAAACCTCCTGCACACCAGAAACTTCCCCATAAACCTGGCCCCTTCTGTACCATCCTTTGGACAGATGGGGG AAACTGAGGTTCCTGGAAGGCAAGACCCTTGCCCCAACTCCCATGGCCACCAGGACTCCATCTCAGGAGGTGTTTTTTCTCAGCCCGGGGCTGCCTT CCAGCAGCAAGTCCAAGGGAGCCATGACCCGAGTTTCCCGGTCACTGACATGCTTTTTTCTCCTTCCTCTCTCTCTTCTGTGACCTGGCCTCCCTGG CCTCAGGAGACAGATCAGTTGGAGGAAGAAAAAGCAGAGCTGGAGTCGGAGATCGCCGAGCTCCAAAAGGAGAAGGAACGTCTGGAGTTTGTGCTGG TGGCCCACAAACCGGGCTGCAAGATCCCCTACGAAGAGGGGCCCGGGCCGGGCCCGCTGGCGGAGGTGAGAGATTTGCCGGGCTCAGCACCGGCTAA GGAAGATGGCTTCAGCTGGCTGCTGCCGCCCCCGCCACCACCGCCCCTGCCCTTCCAGACCAGCCAAGACGCACCCCCCAACCTGACGGCTTCTCTC TTTACACACAGTGAAGTTCAAGTCCTCGGCGACCCCTTCCCCGTTGTTAACCCTTCGTACACTTCTTCGTTTGTCCTCACCTGCCCGGAGGTCTCCG CGTTCGCCGGCGCCCAACGCACCAGCGGCAGTGACCAGCCTTCCGATCCCCTGAACTCGCCCTCCCTCCTCGCTCTGTGAACTCTTTAGACACACAA AACAAACAAACACATGGGGGAGAGAGACTTGGAAGAGGAGGAGGAGGAGGAGAAGGAGGAGAGAGAGGGGAAGAGACAAAGTGGGTGTGTGGCCTCC CTGGCTCCTCCGTCTGACCCTCTGCGGCCACTGCGCCACTGCCATCGGACAGGAGGATTCCTTGTGTTTTGTCCTGCCTCTTGTTTCTGTGCCCCGG CGAGGCCGGAGAGCTGGTGACTTTGGGGACAGGGGGTGGGAAGGGGATGGACACCCCCAGCTGACTGTTGGCTCTCTGACGTCAACCCAAGCTCTGG GGATGGGTGGGGAGGGGGGCGGGTGACGCCCACCTTCGGGCAGTCCTGTGTGAGGATTAAGGGACGGGGGTGGGAGGTAGGCTGTGGGGTGGGCTGG AGTCCTCTCCAGAGAGGCTCAACAAGGAAAAATGCCACTCCCTACCCAATGTCTCCCACACCCACCCTTTTTTTGGGGTGCCTAGGTTGGTTTCCCC TGCACTCCCGACCTTAGCTTATTGATCCCACATTTCCATGGTGTGAGATCCTCTTTACTCTGGGCAGAAGTGAGCCCCCCCCTTAAAGGGAATTCGA TGCCCCCCTAGAATAATCTCATCCCCCCACCCGACTTCTTTTGAAATGTGAACGTCCTTCCTTGACTGTCTAGCCACTCCCTCCCAGAAAAACTGGC TCTGATTGGAATTTCTGGCCTCCTAAGGCTCCCCACCCCGAAATCAGCCCCCAGCCTTGTTTCTGATGACAGTGTTATCCCAAGACCCTGCCCCCTG CCAGCCGACCCTCCTGGCCTTCCTCGTTGGGCCGCTCTGATTTCAGGCAGCAGGGGCTGCTGTGATGCCGTCCTGCTGGAGTGATTTATACTGTGAA ATGAGTTGGCCAGATTGTGGGGTGCAGCTGGGTGGGGCAGCACACCTCTGGGGGGATAATGTCCCCACTCCCGAAAGCCTTTCCTCGGTCTCCCTTC CGTCCATCCCCCTTCTTCCTCCCCTCAACAGTGAGTTAGACTCAAGGGGGTGACAGAACCGAGAAGGGGGTGACAGTCCTCCATCCACGTGGCCTCT CTCTCTCTCCTCAGGACCCTCAGCCCTGGCCTTTTTCTTTAAGGTCCCCCGACCAATCCCCAGCCTAGGACGCCAACTTCTCCCACCCCTTGGCCCC TCACATCCTCTCCAGGAAGGGAGTGAGGGGCTGTGACATTTTTCCGGAGAAGATTTCAGAGCTGAGGCTTTGGTACCCCCAAACCCCCAATATTTTT GGACTGGCAGACTCAAGGGGCTGGAATCTCATGATTCCATGCCCGAGTCCGCCCATCCCTGACCATGGTTTTGGCTCTCCCACCCCGCCGTTCCCTG CGCTTCATCTCATGAGGATTTCTTTATGAGGCAAATTTATATTTTTTAATATCGGGGGGTGGACCACGCCGCCCTCCATCCGTGCTGCATGAAAAAC ATTCCACGTGCCCCTTGTCGCGCGTCTCCCATCCTGATCCCAGACCCATTCCTTAGCTATTTATCCCTTTCCTGGTTTCCGAAAGGCAATTATATCT ATTATGTATAAGTAAATATATTATATATGGATGTGTGTGTGTGCGTGCGCGTGAGTGTGTGAGCGCTTCTGCAGCCTCGGCCTAGGTCACGTTGGCC CTCAAAGCGAGCCGTTGAATTGGAAACTGCTTCTAGAAACTCTGGCTCAGCCTGTCTCGGGCTGACCCTTTTCTGATCGTCTCGGCCCCTCTGATTG TTCCCGATGGTCTCTCTCCCTCTGTCTTTTCTCCTCCGCCTGTGTCCATCTGACCGTTTTCACTTGTCTCCTTTCTGACTGTCCCTGCCAATGCTCC AGCTGTCGTCTGACTCTGGGTTCGTTGGGGACATGAGATTTTATTTTTTGTGAGTGAGACTGAGGGATCGTAGATTTTTACAATCTGTATCTTTGAC AATTCTGGGTGCGAGTGTGAGAGTGTGAGCAGGGCTTGCTCCTGCCAACCACAATTCAATGAATCCCCGACCCCCCTACCCCATGCTGTACTTGTGG TTCTCTTTTTGTATTTTGCATCTGACCCCGGGGGGCTGGGACAGATTGGCAATGGGCCGTCCCCTCTCCCCTTGGTTCTGCACTGTTGCCAATAAAA AGCTCTTAAAAACGCATTCGCCAGGCTACAGTGTTTATTTCCTCCTAACACCCATTGCCTGGCTTCCTTTTAGTAAGAGAGGATGAGGTTAGATTGT CGAAGGACTACACACACACAGAGATCATACACCCATGCACACACACACACAGACACACACCTATGCAGGAACTCCTTCTAGTCAATGGGTCTACAGC AGGATAAAAGGAAGGCAGACAGTCAGGAGGACTTCCTGTACTCGCAGGCAGTGCCTCCTACTAGAAAAAGTAAGTGGCTACAGCTGGGCGCAGTGGC TTGCGCCTGTAATCCCAGCATTTTGGGAGGCCAAGATGGGCGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTTGCCAAGATGGTGAAACCCTGT CTCTACAAAAAATACAAAAATTAGCCTGGTGTGGTGGTGCACACCTGTAATCCCAGGCTACTTGAGAGGTTGAGGCAGGAGAATCACTTTAACTTAG GAGGCAGAGGTTGCAGTGACACAAGATTGCACCACTGCACTCCAGCCTGGGTGACAAAGTGAAACTGTCAAAAAAAAAAAAAAAAGTAAGGGGTCAG AAGGTTAGCCTGCAGGTGTGGGATCACAGAGGTCTCCTAGTGATGGAGCTTGTATGCTCTATGGGTTAAAAACAGACGCTAAGGAGATAAACTATAC ACAGAAGAAGCTTAATGGGCTGTGCACAGTGGCTTGCACTTGCAATCCCAGCTCTTTCGGAGGCCGAGGTAGGAGGCTAGGAGTTCGAGAACAGCCT GGGGCAACATAGTGAGACACCCCCCACCCCAACCCATCTCATTATGTTGAGAAAAAAAAAAAAAAGAGGATCTTGAGAAACTTGCACAGCAAACTAC TAAAGACCACTCAGGCTAGGAATGAGGCGTCATCTTGGATTTTTTACAAACTACAACTACAAAAAACAATTATTTTACACTGAAGATGTGTTTCCTT TTGTTTTCCATATGACCACTATTGGGGCCAACCCAAGACTGACTGAAGCAAATATATGACCATTTTTTTTTTTTACACATAGAGTGGAGCCATCCCC ATTGCAAAATCCTAGCCGTCTCTTATTTGCATAACAGCAAGTCCTCTGGCAATTGAGGTGAGGGTCCAGGGGTCGCTCAGACGCTTTGGTAAATCAA TAAGCAAGGGAATTTGTCATGGTGGAATCCATTTATTAATTCACTCAAAAAAATGTGCTAAGCACCTACCCAACTGTGCTGGGAGTTGGGGACACTA TAGGGACTGAGCCTCAGGTCTTGCCCTCCTGGGGCTCACAGTCCATTGGGGGACACACACCGTTGCCAGTCAGGGACAACCTAAAGTGGATTGGGTT TGGCAAGCCCATGGGGCTAGGGAAGCACAGCAGGGACACCTAGCTTGGACTGGGAGTCGGGAAAAACTTCCTGGCGGAGGGGACAGCTGAGCTGAGT CCTAGAGGAGGATAGAGAGTATAGAAAGAAATAGAAAAAGGCCAAGGCCAAGAAAATAGCACAGCCATAGATCTGTTGGTGGGGAGAAGGCTTGATA CATTGAGAACGCTTAGAGGGTCGGGTGCGATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCAGGCATT CAAGACCAGTCTGGCCAACGTGGCGAAACCCCGTCTCTACTAAAAAATATATATATATATATACAAAAAATTAGCTAGGCATGGTGGTGGGCACCTG TGATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGAAAGTGGACATTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCT GGGCAACACAGCGAGACTCTGTCTCAAAAAAAAAAAAAAAAGAAAGAAAAAAAAGAGAAAACTCAGAGATTCGTGGAGACTGGAACCACGGGTGTGG AGAGAGGGGTTAGTAGAGACCAGATTCTGCAGGTACTATAATGACATTCCCAGGCTAAGGAGTTTAGATCTTTTCTTCAGGGCACTGGGGAGCTATT GCAGGTTTTGAACACGAGAGGGGCAGGGGCAGGTTTGTGATTTAGGAAAGACCCCTCTGGCCCCAGACTGAGCGTGACTGGAAGGGAGAGGAGTGAG ACTGAGCAGGAGACCAGGGAGGAAGTGGGGTGGGGACCCTGCAGGGTGGGGTGAGGAGGAGTCCAGAACAGGGCCAGGGACATGGGACAGAGAGGAG GGGAAGGATTCAGGAGACACTCGGGAGGCAGGACAGTTGGGCTTGGTGAGCAGCCGGCTTGGGAAGGAAAATACAGGGCAGTAATAAATAGCATGGG TCAAGTGGTCTGAGTGAGGCTGGGAGTGGTGGCACGCACCTATGGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGGATTGCTTGAGCCTGGAAGTTT GAGGCTGCAGTGAGCTATGATCGTACCGCTGCACTCCACTTTCGGTGACAGAGTAAGACCCTGTCTCAAAAAAAAAAAAAAAAAGGAAAAAAAAAAA AAGACACTGCCTATGAGTTAACCCTGCTCTACAAGGAGCAGTTTTTAAAGTAAAATTAAAAAAAAAAAAAAAAAAGAAAGAAAGAAAGAAAGAAAGA GAGAGAAAAAAGAAAAAAGGCTGGGTTGCCTTGGACAACAGACTTCATCTCCCTGAGCCTCCATTTCCTCATCTGTAGAATGGGGGCTGTTAAGAGG AGTTGCAAGGCTTGTGCATGCCAGCAGTAAGTGCAGAGTGACGGTGCAATTATCATTACCCCCATCATCTTTATTGGGGTCAGCCTGAACCCTCGAT ATCCCATAATATTCACCCCCATCCTTCAAGGGTCTGCCCTAATGTTCCCATGACACCCGACCAGCTCAGCTCTCCTTATGAGAGGGCCTCACTTTTC TATTCCCTTTGCAGCCGTTATCCCCTTTGTAGTTGTTAATTAAGTGTGTAATTACATGATGGCTTAATGTTTGTCTCCCCCACTGGGCTGACTGCAC CAGGAGACCAAGGCCAGGGCTGTCACCCACCGCTGCGTCCTCAGCAAATGCTTGTTTGATGAGTGAATGACAGATGAACAAATGGGCAAGTATTTGA CTGATTAATCACGGCATGCGTGATTAAATAAATGAGTGAGCAAACGACTGAATGAGTAAGCAATTGAAGGGGAGAGATCTAGGATAATTTCCAAACT GCCAATATCCCAGAACTGGGTAGATGACTTTTTCTCCGTCTTTTGGAGTGGGTTTTTATACTCCGGAGGGGGAAATAAGTAACGACAATCAGAGATC GGAGTGACAGAGAATGAGTTTGCGATGCGGAAGGCCGCAGCGACCTCTCCAGGTGCAGGCTGGAGGAGCGCCTCCCGGGCAACAAGCAAAATAAGTC CGGTTCGATAAGTAAGATTCAAGGCGCTTAGTTACTACCGCCCGAAAGGTGGAATTGAACCACTCTGTCGCTAGACAGCTACAGGTTTGAAGCCTGC ACCCCAGACCACTGAGGATCATCCGGGCAGGACAACCTTCTTCCCGCGCAGCTATATAAGGATCGCAAAAGCTTACCTTTTAGAGTTATGGTCGCGT CCTTTGGAAAGGTGTGAGATGGTTGACTTCAAGGGCTATAAGTTCTCCCCACTCATTTATCGTGAGAGATGTCCTTGTAAAACGTTGCCTTCACTTC ATATAGTATGAATCATCCTCGCTCCCCAAACCGTCTCATTTACATAGCGCCACGCATTCTGGGAAGCAGCGTTTGAGCACCTGGCAAGCTGTTAAAG GGCCCAGGACCCCCTTTTTCCAAAATGAAAAGTCAGCTTTTTAAGAGGAGAGATTCATGATTCGGCATTCAGAAGCGCCTTCTCGGAAAATTCCGAA TTCTCTTTCTGCGGAGGAGTGGTGAGTGGGTTCCTGTTAGAGTCTGATTCACCCTGGCCCCAAAGGCGCTGAGCAGGCGGCTATAGGGCTGGTGCGA CACCTGCTGTTCTTTTATGGAATTGCGTAGGCCGATGGAGCTCCGCGTTCATTCAAACGTTTATTGAGCGTCTACTGAGTCCCAGGAACTGTCTCGG TGCTGGTGACGACAGACATCCTGTCCCGATTGAGTTTAAACACTAGACATAACCAATTTCTGCACTTGCGTTTTATGGTTGGAGAAACTGAGACAGA CTCAGAAACGGATAGTACCATATTCCGGTTAAAACAGCCCATCCACTTAGGGAAATCGAACTTGTGTTACAATTTTTATTACAAAAAAGGTGATTCT TTTTTCTTAAATTTTTACATATTTAGGAGGTACAGGTGCCGATTTCTACATGCATATGTTGATTGCATCGTGGTGAAATCTGGGCTTTTAGGTGTAC TCATCACGAAAAATTATTCAATATTCTAAGTCAGTGATTCTTTGACAATACCATTCTCCTGCATGAAACTCTCCCATGACTTCCATTTCAGAGTAAA AGTCAAAGTACTCACCCTGCTTTACAAATCCCTGTAATCCAGCCCCTTTGGTCCCTCTGACCCTGTCTCACATACTCCTCTTCCCTTGGATATTATT GGATTTAGGCACACAGATGTCTTGCTGCACACATGGATCATGCTACCACCACAGGGACTTTGTGCTTGCCGATCCCCTAGCCTGGATCTCCTCTTCA CATGTTCCCATGGCTCATCGCCTCCCTTCACTCTGTCATCTGATCAAATGTCAATACCAAAAACTCACTGAGTGACCAGCACTCAGTGGGGCCTTCC CTGATCCCAGTTTAAAATAGCGAGTGGCGGCCGGGCGCGGTAGCTCACGCCTGTAACCCCAGCACTTTGGGATGCCAAAGCGGGTGGATCACGAGAT CAGGAGATGGAGACCATCCTGGCTAACACGGTGAAACCTTGTCTCTACTAAAAATACAAAACATTAGCTGGGCGTGGTGGCGGGCGCCTGTAGTCCC AGCTACTCGGGAGCCTGAGGCAGGAGAATGGAGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCTGAGATTGCTCCACTGCACTCCAGCCTGGGGGAC AGAGCGAGGCTCCGTCTCAATAAATAATAAATAAATAAAATAGCTAGTGGCTGGGATCGGTGGCTCAGGGCCTGTAATCCCAGAACTTTGGGAGGCC GAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGGCCAGCCTGGCCAACATGGTGAAACCCCGTCTCCACGAATGATACAAAAATTAGTCAGGCAT AGTGGCTCACGCCTGTAATCCCAGCTACTCGGGAGTTTGAGGCAGGAGAACCGCTTGAACCGGGGAGGCAGAGGTTGCAGTGAGCTGAGATGGTGCC ATTGTACTCCAGCCTTGGTGAAAAGAGCAAAACTCCATGTCCAAATAAAAGTAATAATAATAATAAATAAAATAAAAATTTTTAAAAAGCGAGCTCT GTCACTCTATCCCCTTACCCTGCTAGACATTTCCCCACCACTCTGATCACCACCTGCCATTTTCTGTGTCTATTTGCTTACCGTCTGTCTGCTTCTG TAGAATATCAGCACCATGAAACTATGCACTTTATTTTTGATCATTGCTGTATCTCTAGTGCCTAAAAAGTGCTTGAGAACATAGCAGATGTTCAGTA AATGTTTGTGGAATGAATAAAAGAATATCATCACTGTCTTTTTTTCATTCTTCTTCCAGACAGGATCTTACTTTGTCACCCAGGCTGGAATGCAGTG GCGCAAAAACGGCTCACTGCAGCCTCGACCTCCCAAGCTCAAGTGATCCTCTTGCCTCAGCCTCCCTGGGATGACAGGCATATACCATCACGCCCAG CTAATTTTAATTTTTTTTGTAGAAACAGGGGCCTCACTTTGTTGCCCAGACTGGCCTCGAACTCCTGGCCTCAAGTGATGCTTCTGCCTTGGGCTCC TAAAGTGCTGGAATTTCACGCGTGAGCCACAGCACCTGGCCTCACTATCCTTCTTTCAGCCTCAGTTTTCTCATTTGTATAACCAGACTAGTACAAC TGATCTCACTGGAGAAATCATGATATAAAATTCTGACACTGGCTGAGGCAACTGGGAGGAGCTCAGTAAAGGCTGTTTCTGCTGGGCACGGTGGCTC ACACATGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACAGGAGATTAGAAGTTCCAGACCATCTGGCAAGCATGGTAAAACCCCATCTC TACTAACAATTCAAAAAGTAGCCAGGCATGGTGGCTCACACCTGTGATCCCAGCTACTCGGGAGGCTAAGGCAGGAGAATCCCTTGAACCCAGGAGG CTGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCATCCTGGGCGACAGAGCAAGACTCTGTCAAAAAAAAAAAAAAAGTTTTTTTTTTTTGG CTGGAATTACAGGCGCCTGCCCCCACACCTGGCTAATTTTTGTTTTTTGTTTTTTTAGGAGAGACGGGGTTTCACCATGTTCACCAGACTGGTCTTG AACTCCTGACCTCAGGTAATCCAACTGCCTCAGCTTCCCAAAGTGCTGAGATTACAGGCGGGAGCCACTACACCTGGCCAATAAAGGCCGTTTCAGT CTTCAATCTGTTTTGAGCTTGGAGGCTTTAGTCATTCCGAGACCCAAAATCTCAATCAGACCCTCTTCCACCACTTTTTGTGATAGATCAATAAACA TTTTGTCTTATGGGAAGTTTAACTAAGAGTATCTTTAGAAAGTTTTGGACAGGCGCTGTAATCCCAGCACTTTGGGAGGCCGAGATGAGCGGATAGC TTGAGCCCAGGAGTTAGAGACAAGCCTGGGCAACATAGTGAGACTCTGTCTCAAAAAAAAAAAAAAGAAAGAAAGGAAAAGAAAAAAAGAAAAAAAA AGTATTCCCTCTGCTTGGCAAATCCAGATTCAAGATATATCCCCTAAACCCTCTTTGTTTTAATTAGATAGTTGCTGCTAGGCACCTCTGTATACAA ATTCTGAGGATGTAAGGACTCCTTGGAACACCGTTATCTGTCTCCTAATATGTGACGTGTGTATGACGAACAAGTGAGTTTTTTTTTTTTTTGTTTC TTTTTTTTGGTTTTTTGTTTTGAGACGCAGTCTCGCTCTGTCGCCCAGGCTGGAGTGTAGTGGCGCGATCTTGGCTCACTGCAAGCTCTGCCTCCCA GGTTCACGCCATTCTCCTGCCTCAGCCTCCCTAGTAGCTGGAACTACAGGCGCCCGCCACCACTCCCGGCTAATTTTTTTGTATTTTTAGTAGACAC GGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCA CCGAGCCCGGCTTTTTTTTGAGATGGAGTTTCCCTCTTGTTGCTCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAACTTCCGCCTCCCGG GTTCAAGCGATTTTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACGCCCGGCCAATTTTGTATTTTTAGTAGAGACATGG TTTCTCCATGTTGGTCAGGCTGGTCTCCAACTCCCGACCTCAGGTGATCCACCTGCCTTGGCCTCCTAAAGTGCTGAGATTACAGGCGTGAGCCACT GCGCCTGGCTGCACAAACATTTTAAACGTCAATATTTTTGTGTTTATTTTTACTATTGTCTTCTATTTCTGGCAAGCAATACTGGTTTCTGGTGGCA AGGTAACCTTTCTTCTTAAAATACATTTGTTATTATATTATTAAATATTAAACCAATTTTCAAGAAAAATATTAGATAAATAGCAGAACAGGTTGTA GAAAGATGAAGGTCATGTGGGGAATGACTGAGGTTTGGGAAACAATATTATAACTCCTTACTGTGCATTTATTATATGCCAGGCCCAATGCCAAGGG CTTTACATGTAGGTATAGTTATGGTTGACAGTTTTCTTCTTTTTCTTTTCTTTTTTTTTGAAACAGGGTCTTGCTCTGTCGCCCTGTCTGGAGTGCA GTGACGCAATCTCAGCTCACTACAACCTCCACCTCCTTAGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGTGTAGCTGGTCTTACAGGTGCCCACCA CCACATCCGGTATTTTTAGTAGGGACGAGGTTTTACCATGTTGGCGAGGCTTGTCTTGAACTCCTGACCTCAGGTGATCCACCTTCCTTGGCCTCCC AAAGGCTGGGATTACAGGTGTGAGCCACTGCACCTGGCCTCTTTTTTTCTTACTTAATTTTTTTGTAGAGATGAGGTCTATGTTGCCCAAACTTGTC TCGAACTCCTGGCCTTAAGTGATCCTCCCTCCTTGGCCTTCCAAAGTGCTGGGATTGCAGACGTGAGCCATCGTGCCCGGCCTAATAAGTTTTCCAT TTGAGGAAACTGAGGCTTTGAGAGATGAAGTCATATGCTCAAGGTCATACAGCGAAGGGGTAGTAGAGCCAGGATTCAAACCCAAGTCTGTGGATCT TTAGACCTCAGTGTTCTCCCAGTCTCCCCACGGGTCCCTTTGCTTCATCCTTTCCGAGTTTAGTTGTCTTTTTTGTTGTTGTTCTTGTTGTTGCTGT TTTTTGATAGAGTCTCGCCCTGTTGCCCAGGCTGGAGTGCAGCGGCATGATCCTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCT GCCTCAGGCTCCCGAGTAGCTGGGATTACAGGTATGCGCCGCCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCATCATGTTGGTC AGGCTGGTCTGGAACTCCTGACCTCAGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTACGCCCAGTATGTAGTT TTTTTGTGTTTTGTTTTTGTTTTTGTTTAGAGACAGGGTCTCCCTCTGTAACTCAGGCTGAAGTGCAGTGGTGTGATCATAGCTCTCTGTAACCTCG AACTCCTGGCCTCAAGCAATTTTCCTGTCTTAGCCTCCCAAGTACCTGGGACTACAGGCATGCACCACCACGCCCGGATAAATTTTTTTTTTTTTTA GAGACGGGGGTCTTGTTATGTTGCTCAGGGTGGTCTCGAACTTTTGGCCTCAAGTGATCTTCCCACATTGGCCTCCCGAAGTGTTGGGATCACAGAT GTGAGTCATCATGCCAGGCCTCAGATTAGTGTTGAAACTGGAAGTCCAGGGAGGCCCTGTATTTGTTCCCGAGGCAATCAGGGTGGGGAGACGTGGG TGGATGAGAGAAGTTTGTGAGGCAGGATAGACACAGCATTGTGACTGATTGTTTGTGGGAGGTGAGTGTGTAGAAGTCCAGAGCCATACCTGGGTGT CTGGCCTGGTGACACCGTGGGCAGTGAAAACATCTCTGAGTTGGAAATCAGGTAGGATGAAGAAGACGTTTGGTTAGATTTAGGGTGGAAGGGGCAT CCAGAGGCCGTTGGACACGTGGGTTTGGGCTCAGTTGAGGTGGCTGCACAGTAGGCAGGGTGTGGGATCCATTAGTGATGTCTGCCTTGAGCACAGG CATGGGAAGTGGCTGCCAAGGCTTGGCTAACCCTGGAATGGGTGGTCTGTCAGCATCTTCCCCTCAATCATTTCTTTCTTTTTTTTTTTTTTGAGAC AGAATCTCGCTCTGTCGCCGAGGCTGGAGTGCAGTGGCGCAATCTTGGCTCACTACAACCTCCATCTCCCAGATTCAAGCGACTCTCATGCCTCAGC CTCCCGAGTAGCTGTGATTACAGGCATGCACCACCACACCCGGCTAAATTTTGTATTTTTAGTAGAGATGAGGTTTCACCATGTTGGCCAGGCTGGT CTTGAACTTCTGGTCTCAAGTGATCCGCCCTCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCTCCCCTCAATCATT TCATAACCTACACAGATGGCAGAG HUMAN SEQUENCE - mRNA CATTCATAAGACTCAGAGCTACGGCCACGGCAGGGACACGCGGAACCAAGACTTGGAAACTTGATTGTTGTGGTTCTTCTTGGGGGTTATGAAATTT CATTAATCTTTTTTTTTTCCGGGGAGAAAGTTTTTGGAAAGATTCTTCCAGATATTTCTTCATTTTCTTTTGGAGGACCGACTTACTTTTTTTGGTC TTCTTTATTACTCCCCTCCCCCCGTGGGACCCGCCGGACGCGTGGAGGAGACCGTAGCTGAAGCTGATTCTGTACAGCGGGACAGCGCTTTCTGCCC CTGGGGGAGCAACCCCTCCCTCGCCCCTGGGTCCTACGGAGCCTGCACTTTCAAGAGGTACAGCGGCATCCTGTGGGGGCCTGGGCACCGCAGGAAG ACTGCACAGAAACTTTGCCATTGTTGGAACGGGACGTTGCTCCTTCCCCGAGCTTCCCCGGACAGCGTACTTTGAGGACTCGCTCAGCTCACCGGGG ACTCCCACGGCTCACCCCGGACTTGCACCTTACTTCCCCAACCCGGCCATAGCCTTGGCTTCCCGGCGACCTCAGCGTGGTCACAGGGGCCCCCCTG TGCCCAGGGAAATGTTTCAGGCTTTCCCCGGAGACTACGACTCCGGCTCCCGGTGCAGCTCCTCACCCTCTGCCGAGTCTCAATATCTGTCTTCGGT GGACTCCTTCGGCAGTCCACCCACCGCCGCGGCCTCCCAGGAGTGCGCCGGTCTCGGGGAAATGCCCGGTTCCTTCGTGCCCACGGTCACCGCGATC ACAACCAGCCAGGACCTCCAGTGGCTTGTGCAACCCACCCTCATCTCTTCCATGGCCCAGTCCCAGGGGCAGCCACTGGCCTCCCAGCCCCCGGTCG TCGACCCCTACGACATGCCGGGAACCAGCTACTCCACACCAGGCATGAGTGGCTACAGCAGTGGCGGAGCGAGTGGCAGTGGTGGGCCTTCCACCAG CGGAACTACCAGTGGGCCTGGGCCTGCCCGCCCAGCCCGAGCCCGGCCTAGGAGACCCCGAGAGGAGACGCTCACCCCAGAGGAAGAGGAGAAGCGA AGGGTGCGCCGGGAACGAAATAAACTAGCAGCAGCTAAATGCAGGAACCGGCGGAGGGAGCTGACCGACCGACTCCAGGCGGAGACAGATCAGTTGG AGGAAGAAAAAGCAGAGCTGGAGTCGGAGATCGCCGAGCTCCAAAAGGAGAAGGAACGTCTGGAGTTTGTGCTGGTGGCCCACAAACCGGGCTGCAA GATCCCCTACGAAGAGGGGCCCGGGCCGGGCCCGCTGGCGGAGGTGAGAGATTTGCCGGGCTCAGCACCGGCTAAGGAAGATGGCTTCAGCTGGCTG CTGCCGCCCCCGCCACCACCGCCCCTGCCCTTCCAGACCAGCCAAGACGCACCCCCCAACCTGACGGCTTCTCTCTTTACACACAGTGAAGTTCAAG TCCTCGGCGACCCCTTCCCCGTTGTTAACCCTTCGTACACTTCTTCGTTTGTCCTCACCTGCCCGGAGGTCTCCGCGTTCGCCGGCGCCCAACGCAC CAGCGGCAGTGACCAGCCTTCCGATCCCCTGAACTCGCCCTCCCTCCTCGCTCGGTGAACTCTTTAGACACACAAAACAAACAAACACATGGGGGAG AGAGACTTGGAAGAGGAGGAGGAGGAGGAGAAGGAGGAGAGAGAGGGGAAGAGACAAAGTGGGTGTGTGGCCTCCCTGGCTCCTCCGTCTGACCCTC TGCGGCCACTGCGCCACTGCCATCGGACAGGAGGATTCCTTGTGTTTTGTCCTGCCTCTTGTTTCTGTGCCCCGGCGAGGCCGGAGAGCTGGTGACT TTGGGGACAGGGGGTGGGAAGGGGATGGACACCCCCAGCTGACTGTTGGCTCTCTGACGTCAACCCAAGCTCTGGGGATGGGTGGGGAGGGGGGCGG GTGACGCCCACCTTCGGGCAGTCCTGTGTGAGGATGAAGGGACGGGGGTGGGAGGTAGGCTGTGGGGTGGGCTGGAGTCCTCTCCAGAGAGGCTCAA CAAGGAAAAATGCCACTCCCTACCCAATGTCTCCCACACCCACCCTTTTTTTGGGGTGCCCAGGTTGGTTTCCCCTGCACTCCCGACCTTAGCTTAT TGATCCCACATTTCCATGGTGTGAGATCCTCTTTACTCTGGGCAGAAGTGAGCCCCCCCTTAAAGGGAATTCGATGCCCCCCTAGAATAATCTCATC CCCCCACCCGACTTCTTTTGAAATGTGAACGTCCTTCCTTGACTGTCTAGCCACTCCCTCCCAGAAAAACTGGCTCTGATTGGAATTTCTGGCCTCC TAAGGCTCCCCACCCCGAAATCAGCCCCCAGCCTTGTTTCTGATGACAGTGTTATCCCAAGACCCTGCCCCCTGCCAGCCGACCCTCCTGGCCTTCC TCGTTGGGCCGCTCTGATTTCAGGCAGCAGGGGCTGCTGTGATGCCGTCCTGCTGGAGTGATTTATACTGTGAAATGAGTTGGCCAGATTGTGGGGT GCAGCTGGGTGGGGCAGCACACCTCTGGGGGGATAATGTCCCCACTCCCGAAAGCCTTTCCTCGGTCTCCCTTCCGTCCATCCCCCTTCTTCCTCCC CTCAACAGTGAGTTAGACTCAAGGGGGTGACAGAACCGAGAAGGGGGTGACAGTCCTCCATCCACGTGGCCTCTCTCTCTCTCCTCAGGACCCTCAG CCCTGGCCTTTTTCTTTAAGGTCCCCCGACCAATCCCCAGCCTAGGACGCCAACTTCTCCCACCCCTTGGCCCCTCACATCCTCTCCAGGAAGGCAG TGAGGGGCTGTGACATTTTTCCGGAGAAGATTTCAGAGCTGAGGCTTTGGTACCCCCAAACCCCCAATATTTTTGGACTGGCAGACTCAAGGGGCTG GAATCTCATGATTCCATGCCCGAGTCCGCCCATCCCTGACCATGGTTTTGGCTCTCCCACCCCGCCGTTCCCTGCGCTTCATCTCATGAGGATTTCT TTATGAGGCAAATTTATATTTTTTAATATCGGGGGGTGGACCACGCCGCCCTCCATCCGTGCTGCATGAAAAACATTCCACGTGCCCCTTGTCGCGC GTCTCCCATCCTGATCCCAGACCCATTCCTTAGCTATTTATCCCTTTCCTGGTTTCCGAAAGGCAATTATATCTATTATGTATAAGTAAATATATTA TATATGGATGTGTGTGTGTGCGTGCGCGTGAGTGTGTGAGCGCTTCTGCAGCCTCGGCCTAGGTCACGTTGGCCCTCAAAGCGAGCCGTTGAATTGG AAACTGCTTCTAGAAACTCTGGCTCAGCCTGTCTCGGGCTGACCCTTTTCTGATCGTCTCGGCCCCTCTGATTGTTCCCGATGGTCTCTCTCCCTCT GTCTTTTCTCCTCCGCCTGTGTCCATCTGACCGTTTTCACTTGTCTCCTTTCTGACTGTCCCTGCCAATGCTCCAGCTGTCGTCTGACTCTGGGTTC GTTGGGGACATGAGATTTTATTTTTTGTGAGTGAGACTGAGGGATCGTAGATTTTTACAATCTGTATCTTTGACAATTCTGGGTGCGAGTGTGAGAG TGTGAGCAGGGCTTGCTCCTGCCAACCACAATTCAATGAATCCCCGACCCCCCTACCCCATGCTGTACTTGTGGTTCTCTTTTTGTATTTTGCATCT GACCCCGGGGGGCTGGGACAGATTGGCAATGGGCCGTCCCCTCTCCCCTTGGTTCTGCACTGTTGCCAATAAAAAGCTCTTAAAAACGC HUMAN SEQUENCE - CODING ATGTTTCAGGCTTTCCCCGGAGACTACGACTCCGGCTCCCGGTGCAGCTCCTCACCCTCTGCCGAGTCTCAATATCTGTCTTCGGTGGACTCCTTCG GCAGTCCACCCACCGCCGCGGCCTCCCAGGAGTGCGCCGGTCTCGGGGAAATGCCCGGTTCCTTCGTGCCCACGGTCACCGCGATCACAACCAGCCA GGACCTCCAGTGGCTTGTGCAACCCACCCTCATCTCTTCCATGGCCCAGTCCCAGGGGCAGCCACTGGCCTCCCAGCCCCCGGTCGTCGACCCCTAC GACATGCCGGGAACCAGCTACTCCACACCAGGCATGAGTGGCTACAGCAGTGGCGGAGCGAGTGGCAGTGGTGGGCCTTCCACCAGCGGAACTACCA GTGGGCCTGGGCCTGCCCGCCCAGCCCGAGCCCGGCCTAGGAGACCCCGAGAGGAGACGCTCACCCCAGAGGAAGAGGAGAAGCGAAGGGTGCGCCG GGAACGAAATAAACTAGCAGCAGCTAAATGCAGGAACCGGCGGAGGGAGCTGACCGACCGACTCCAGGCGGAGACAGATCAGTTGGAGGAAGAAAAA GCAGAGCTGGAGTCGGAGATCGCCGAGCTCCAAAAGGAGAAGGAACGTCTGGAGTTTGTGCTGGTGGCCCACAAACCGGGCTGCAAGATCCCCTACG AAGAGGGGCCCGGGCCGGGCCCGCTGGCGGAGGTGAGAGATTTGCCGGGCTCAGCACCGGCTAAGGAAGATGGCTTCAGCTGGCTGCTGCCGCCCCC GCCACCACCGCCCCTGCCCTTCCAGACCAGCCAAGACGCACCCCCCAACCTGACGGCTTCTCTCTTTACACACAGTGAAGTTCAAGTCCTCGGCGAC CCCTTCCCCGTTGTTAACCCTTCGTACACTTCTTCGTTTGTCCTCACCTGCCCGGAGGTCTCCGCGTTCGCCGGCGCCCAACGCACCAGCGGCAGTG ACCAGCCTTCCGATCCCCTGAACTCGCCCTCCCTCCTCGCTCGGTGA

[0295] TABLE IV MOUSE NOMENCLATURE ICSGNM Cmkbr7 Celera mCG1536/2 HUMAN NOMENCLATURE HGNC CCR7 Celera hCG1E43840 MOUSE SEQUENCE—GENOMIC NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGGAGTTCCATTCTCAGCCCGCTGCTACTGCCTGTGAGCCTCCTTTGGGAAAGTC CTTAATTTCTCTAGTTCTGTTATTTCCTCATCTCTAGAATGGGCATCACGACACTGATTTCACAGAGTTGTTCCGAGATGAAATGATGTGATGGAGT AAGTACTAGTTCCCAGCCTCTCAGATCCTGGAAATGCGTGTCCTGCCTCTCCCTCTGGAAGCTCCCTGAAGGCCAGGCTTTGCGTCCTTCATCCAAG CTTGGATGAGTATTTTAAAAGAGTCTCCGTGAGTTTTGCTCATTAGCCAAAACGGATGCTGGCCTTTGGAAGCGGGGCGGATGACTCTGCGTGGAAA TATTCTTCTCTGAGTTTCCCTCCTCTGCCTACTTCCTCGTGAGTTCTATGTGGCATCTATTTGAGGTCAAATCTATTGAAATATACTTCAGCTTAAC TCTAGGTGCCTTTTAGTTGAGCACCAAGAATATACTAAGTGCTATGTAAGAAATAGATAAAGGACCCAGTATGGAGGAGGAGAAATACCAAGCCAAG CCTAGTACTCAAACCGCAGACAGTGATAGGGACAGCCGGATCGCTTTCTGTAGGCTTGAGGGTTTCTGAAATTCTTCAGGGAATTGGGAGCTCTTTG AGCTGGACTTTTTTAAGCGTATGAGTGTTTGGTCTCTCTCTATGCATCTGTGTCATGAGCATACCTGGTACCTATGCAGAACAGGAGAGGGTATCAG ACACCCTGGAACTACAGATAGTTGTCAGTTGCCATGTGGGTGCTGGGAAACCCACCCTAGGTCCTCTGCAGGAACAGCAAGTGCTGAAGGGACTACT GAGCTGTCTCTCCAGCCCCTTACGTTAAATCTTGAAGAACGGGTTAAAAGATGACAGAGCGGGGGAGAGGTACCGGAGAGAAAAATGTGTGAAAGTA GTCAGGGCCTTGACCTGGAAGAGTTAGAGAACAAGGCAGATGCAGTTGGCAGGTCCGGAGCAACAGCTCCTGAGTGTTCAATGGGCCAAGTTGAGAG GGGCTTTGGATGCCATGAAAGGTTGCCGAGGAGAAGGAAGTAGAGAGTGAGTCCTTCAGCTACCACAGGGGAAGGGTGGGAAGGGGGTGAGGAGATT TCCTAAATGTGCATCATTGGCCTTCTGAGGTCTTCAGAAGACGACCAGTGGGGTCCCCAAAGGGTGAGACCAGACAGAACAGACAGCCACTATTCCC TACTCTGACCCCCTACCTCAAGAGGAAAGGACGAAGAGAGAGCTGAGAAGAGACCCTGAGCCTCTTCACCACAGCAGACAGGACCAAGTTTCAGCAG GCACCAGGACACTCAGGTGTCTACGTCAGTCGCTAGCTATGCACATGGGTACCCTGGGCATGGAAACTACAGACTGGCTTTCTAACACATCATTTTG CCGTGAGACCAATCCCAGCATTCCCTCTATTGTCCTCAACAGAATCAAACGTCCAAGCTAAGGGGCTTGCCACCTCTCCAAAATAAAGGTCACCTTA GAGGTCAAGAAAGCATTGACACAAACCTTGGGTAAGCCCTAAGACTGTAACTTGGGAGTTGTCATGACAACAGGGCAGTAGAGCCATCTCTACTCTC TCCTAAATGGCACGAGGTTTAGATGAGTAACTCTGAAACAACAGACCCCACCCCTGTTTTCCTATTTACCATCTTCAGACCCCTCCTCACCTGTGCC CCAGCCCTCTCCTCTAGGACCTTAGCAACTTGAACAACATAGACACACACGCCTCCTCTCAGTGTCCAACAATGAGCCCTCCCAGCAAAACAGGAAG CCTCTTCCTGCCAAGGCATTGTGCTTGCCCTGTCACGTGTCAGGAAACCACTACCGTGCCATGGCAACAGGTGTTGCTGAGACCTTAGCCTTCCCGC CAACCTGTGCCCTGCCCTTCTCTCTCCTCCTTACTCCTAGAGAGTGTCCTCGTTGTGCAGTCTCCTTGACTCACCTGGACACTGCTGTGAGTGAGCG TCCTAATTACCTTAACTTGGATGAGAAGACTAATTCACCCTATAAGTCAGTGGCCCAGGGCCAGGGCTTGGCCCTTAGACTGCATAAAAAGGAGAAA GCTGCCGACTGCAGGTGTTCATCTCCCCTTGTTTCCTCCCTATCAGTGCAATGTCACCAGCCACTCCAAGCCAATGTCACCACCAGCCACCCCAAG CTCCTGCTGCCATGATTCCCCAACCAGGATGGACTCTACGCTGGAACTGTGAGCTGTATTAACGCTTCTCCCCTAAATTTTTCTTGTCAAGGTGTTT TCATCACAACAGCAGAAAAACCAAAACCAACTGACACTTCCTCCTTGCAACTGGCAGCTCACATCGCTTGCTCCTTTCCCATTTGGACACCAAAGAT CTCACTGATCATCATCCAAACACAGTTCTTCATGCTAGCCAGGCAACATAAGAATGTACCTGTGTGGAAATTTAGCAAGCTTCTTAGCTCTTTTGGA TCGCAAAAGTCTAGGTAAGGTCTGAGATGACTCTCTCTCAAATTCCAATATCCCTAAATGTATGCCAGACCTTCCTGTAAGGTTGCTGAGTCCTGAA GCTAAACTGACTGTCTTAGTTAAGGTTAGTAGTGCTACCACACCAAAAACAAAACAAACAAACAAAAAAAAAATGAACAAGCCAGGCGTGGTGGTGC ATGCCTTTAATTCCAGCACTCGGGAGGCAGAGGCAAGCAGATTTCTGAGTTCAAGACCAGCCTGGTCTACAAAGTGAGTTCCAGGACAGCCAGGGCT ACACAGAGAAACCCTGTCTCAAAAAAACAAACAAACAAACAAATAACAGCAACAACAACAAAAACATCAACAAAAGCTATTTGGTTGGGGAAGGTTT TATTGGCTCACACTTCCATATCATGGTCCATTATCAAAGGAAGTCAGGGCAGGCACTCAAGGCAAGGCAGGAACCTAGAGGCAGGAGCTGATGCTGA GGCCATGGAAGAGTGTTGCTTACrGGCTTGCTGAGTCTGCTTTCTTTTATCATCCATTGTTACATGGAGATTAATCAAAGTTGCATGAAAAGAAGAG AGAAGGACCTCCTCAGACGCAGATGGAAGCATGTGGTCCTTTGTTAGGACTCTGAAGGGCAGTGGTCTCTCAGAAAAAGGCTGTCAGCCAAGGCACA GGGGGTTTGAGGGTTTTATAGGACAGAAAAGGAAGCGTTTGTGGTTGGAAAATTCCATCTGCAGATCTGTTTCCTCAAGTCTCAGCACTGTAAATAC CAACGGAGGTTCTTATCCATTAGTGAATTTCTTGTCAGGAGAATCCCGGCTCCTAACTGCCTGCAGATGTTAGCAGTGTATCCCTGGTGCCATCCGG AGTTTCTCAGCTCTCCTGGGGCTTTTAGGTCATTAACCCTTCACCCAAGACCAGCAGCAGCAGCACCGCCCAGTGAACTAGCCTCAGAGACTCACCC TACAGCCCAATCTGATGGACGCATTTTTCTCAACTGTGGTTCCCTCTTCTCAAATGACTCTAGAGTGTGTTAAATTGACATAAAACTAGCCAGCACA CTGATGATTCTGGAGTGAAATCAAAAGGAGCTTGAAGATGAGGGTGGGGACAGAGGCAAGGGTATGTCTTAGACTTTACTCATTGAATTGCAAGCCG AGAAGGATTAGAAGACATCAGCAGTATCAGTGGACAAGTGGCATTTGAATGCCATATGGAAGAAGGACAATAAGAAGTTCCTGCAGACCTGGTTCCA TCCAGAAGCCTCTGCTCTGACTCCTCTCCCGGGACTCTTTAGGTCAAGGACTTTCTCCAGGGGTCTCAAGACTTTCTGTGTTCCTTTATACTAAGTT TTCTTTCATCCTGTGAACAATCAAGTCATCAGTGAGGTGGTTGGGTGACATGGCCCATAAAGATGACTTCCAGGGACCGGGTTCCTGCTCACACTCT GAAACCTTTGCTCCTGGGCAAAACTTCCCCTAAAGAACAATGACACACATTCTCAGAGAACAGAGAACAATAAGCCGTGTGTAACAACATCTTCCAG AGAGAGAGAAGCGTGGATTTAGTCCTTTTGGGCCACGCTCAGCATCAGCAGGAGCTAGCTTGACATAAGGAGAAAAGCCCCTTAGCTTGGAGCTAAA GGTCACATCACTTTTAAGTCTCAGTTTCTACAGCCACAGAACAGAAAGTTACCAAACACAGCAGCCTGAGGGTTTCATGTGAGAAGGTCATGGAGTC CCAATCACTCACTCCTTAAACTTGACTCTGTCTGCAGCCCCCAGCTGGCCTTGAACTTGTGGCAGTGGAGAATGTGCTTGAAATACAGAAGCCAAAT AGAAACCTGGAAATGTTACTTGTCACTGGTTGGAAGCCCTGGACCATGGTGGATGGACACTCGATTCTGAGTACCTACCCCCAGGACTCCCCAGAGT AGATGTTTATAGTTGCTGGATGATGGTGGATGGACAGACAGACACGGACTGGCGCCTAAGAAAAGTCTAGCATGTCATCACGTACTCCAGCAGCCCG AGAGCTTCATGTCAAAGACACAAAGCAAAGCCATCTCATGTGCCAACCACAACCTAGCCAATGGCCAGTTATCAAAGCCAGAAATCTGGCCTAGAGG CCATAGCACTCTAAAATGAGGCCAAGTTAAACTATGTGGCGCTCTCTGCCCTCCAAACTGCCAACTTCAGCAGCCCTTTTGAAGCTGAGTCAAACTC CTGACCATAGCGTTTCTTTTCACCACTGCCTTCCTCCCTCACCTGGCCCACTCCCTCAGCTCTCTAGGTGCCACTCTTCCCATAGGAGTCTTGGTTG GACTCCTACTGTGCCTAAGCTATGCCAGGCTGTTCCCTAGCTAAGTCCTGCAGTGTTGTGATGCAATATTGTCCTCCATTATTTCCTAAATACCATG AAATATTTAATATATAAAGCCATAAAAAGCCGGGCATGGTGGCTCACACCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGGCAAATTTCTGAGTTC AAGGCCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTACACAGAGAAACCCTGTCTCGAAAAAACAACAACAACAATAACAACAACAAA AAGCCGTAAAAAATAATGCAATGAAGACTTTAGTTCATCATAAATAAAACATCACCTTCCGAGCCCTTCCCAAAATTAAGGTGAGCCTGTTTGTGGG TGCCATTTCTCTTCATATTGTTTGAGAGTGATTGTGTCTTGTCATTTGTCTCACTTTGTGTTCCTTGGTTTTTTGGCCACAGAGTCTCACTCTGTAA AGGTGGCAGATCCAAGTGTGGCAATCTTCCTACCTCAGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTTCTTCTTCTTCTTCTTCTTCT TCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTTTTCTTCTTCTTCTTCTTCATACGGTATTCTGCCTCCAT GTATACCTGCAGGCCAGAAAAGGACACCAGATCTCATTAGAGATGGTTATGAGCCACCATGTGGTTGCTGGGAATTGAACTCAGGACCTCTTCAAGA GCAGCCAGTGCTTTGAATGTCTGTGCTGTCTCTTCAGCCTTCCTCCTCCTCCTCCTCTTCCTCCTCTTAATAATTTACTTTTATTTTATGTACATTG GTGTTCTGACTGTATATATGAGGGTGCCAGCTCCCTTGGATCAGGAGTCATAGACAGTTGTGAGCTGCCATGTGGGTGCTGGGAACTGAACCCAGGT CCTTTGGAAAAACAGCCAGTGCGCTTAACTGCAGAGCCATCTGTCCAGCCCCTGCCTCAGCTTCTTAGTGCTAAGATTACAGGACTTCATCAGAACC GTTATGACCCTACGATGGCTGGATTTGAGAATAAAGCTGTTGGGGGTTGGTTTTAATGCTTTGAATTAATCCAGCCCCCAAAATCGGGAAACTGCAT GTCCAAACACTAAAGATCCTTGTCCCCAATTGGTTTTTGATCAATCAAAAAAGAGCCAATGGCCAATGGTTGGGCAGGTAGACTGAAACAAGACCTT TAGATTTGCTCAGGCTGGGAACTGGGAGAGAGGAAGGAGAGAGCATTGTCGTGGTTTGGAGGGAAACAGATCAGAATTAGAGACCCAAAAGGAAAAG CATCCGAAATGTAGGAGAGAAAGAATTCGGGCCCTGGAGGAACAGCTCAGAAGTGTCTTGGGCAGCAAAGACTGGGGTAGGGGCACCCAGAAGGAGC CAGGGCAACAAAGATAAAATATAGAATTAGAGGGCATTAAGCCAGGAGTACCAAAGGGAAATGTGTTCTAGCCACAGGGAAGATTAGAACTGCCCAG CCTTTGAGCTAGTCAAAGCATATTTAAAATTAACTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCTTCATTCTTGAATCCAGAT AGCTCTTGGGCAGGTGCATGGGTGTGACGAATCGGGAGCACAAAATGATTTAGCTAACTACTGCTACGTAGAGAATCTAAGGAAGTTATTTAAATTA AATAGCACTATAGAGTAGGGTCCTGGTTCCATGGAATTGGTATGTGAGTGACATTACCAGAAATTGACCCTACTGGCCTTTGCCTTGGGACTTCCAG CCTCTAGAACCATGAGGAAACATATTTCTGTTGTGTAAGACATCCAGTCCATGGTATTTTAAGAGTCCAAACAGACTACTCACTCCATGTAAGTTAA GCAAGGCCAAGGATCATGTGTGCTTGTCTTTGGATCAATACTGTCCATCACTATACCTAACACATAAGTGCATGCCAAATATCTGTTTGTTGAATGA ATGAATGAATGAAEGAATGAATGAATGAATGAATTAGATAATTACTAAAACAAAACATATAGGGTTCTGGGGTATGCAAGATGGTTTAATGGGTAAA GGTGCTTGCTGACAAGCCTGACAACCTGAGTTTGATCCCAGGAGTAGACCTGGTGGGAAGAGGAGACTTACTCCTGCAAGATGTCCTCTGACCTCAA CAAGCATGCTGTGCCACATGCCTGCACACAGCTCCTTTCTCCCTCTCCCTTCCCCCACCCCCATTCTCTCCTTCCTTCCCTCATGCCCAACATGAAA GCTCTCGGCTACTGCTCCCATACCTTGTTTGCCTGCCTGCCTCCTGCCATGCCATCATCCACCATGATGGATGTGAACTCATCCTCTGAAACTGTAA GCAAGCCTACAATTAAATGCTTTCTTATATAAGTTACCTTGGTCTTGCCATCTGTTCACAGGAATAAAAAACTAAATACAACAAATTATACATGCCC CCCCCAAAAACCCTTGTAAATGAATATTTATAGCAACAATACTCATGATAACTAAATAGTAGAAACAATCCAAATAGCCAACTAATAGTAGATAAAA CAAATGTGCTATATCCACACAATGGAATATTATTCAGCCACAGAAAGGAGTGGAGAGTTGAAACATACTCCATATAGATGAACCTAATTAAAAGAAG ATAGATATGAAGGTAACATTGTGTCTATTTATGTGCATTAATCAACAGAAGCAAATCTACAGAAAGAAAGTAGGTCTGCGGCTCAGAGCAGTTATGT GCACAGGTGGAAAGGACATGGGAATCATCGGAAATAATGGCTGAGGAGATCTGACTAAAAATGATTCAAAGTTTACCGTGGCGAATAAACGCCGTGA CTATATAAACACCACAGAAATGTCTACTTTAAAAGAGGAAATGTGGGGACGGGAGAGATGGCGCAACAGTTAAGGACACTTGATGCTCTTGCTGAGG ATCCAGGCTCAGTTCCCAGCACCCACACATCAGCTCACAAGGCCTGTAACTCCAGTTCCAGAGGATCTGACGCCGTCTTCTGACCTCCACGGGCTGT AGGCACACAGGTGGTACACAGAAAGGCACTCAGGCAAATGCTCATACACATAAAATAAAAATCAATGAATCGTTTTCAAAGGTGAATTTAGATATGA ACTATAGCTAACTAGAGCTGTTGTCTTTTAAAAGAAAGGAAGGAAACACAGATGAATTCCTTTCTTTCAACCTTCCATTACCTGTCAGTATAACCTC ATGGCCAATTCTCTCCAGAAGCTAGAGGGAAAGTCGTCCGGGAAATGTAGTCCCTGTATGCAGAGCAGAGCAAGGGTATCAAGTGAGTGCCTAAAGG GTTATGTTGTCATGGCAACTGTTTTAACTATTTATTTATCTTATGTATATGAGTACACTGTCACTCTCTTCAGACACACCAGAAGAGGGCATCGGGT CCCATTACAGATGGTTGTGAGCCAACGCGTGGTTGCTGGGGATTGAACTCAGGACCTCTGGAGGAGCAGTCAGTGCTCTTACCCACTGAGCCATCTC TCCAGCCCCCTGTTTTTAACTAGTTAATACAGAAGAAGGGCTAAGTCATTCTGAGCTCTGTGTCGGGTCCTGTCGCTCACTGAATTGTCTACAATCA GTGGCTAGAGATAAAAAAATTTACAGGTGTCTCTCCTGGAAATGGAACATTTAGATATTTGCTCTAGAACTCAATGGCCACCCACAGTCCCCACATG ATCTCTATGCTTGTTTTAAACCCACTCCTTGGACTGGGGAGGTGGCTTAGTAGCTAACAGAGAATTGCCCCACAAACACGAGGAACTGAGTCCAAAT CCCAGAACCCTCATAAGCAGCTTGGCAGTAGCATGAGCATTCGTCATCCTAGCAGTCCCCCAAGGAGATGGGAAGCAGAGACAAGAGACCACGCACC CAGAAGGCCAGCTCACCTTAGTATAGAATGGGCCACTCAATAAAGACGTGATACCTGCAACAGAATGGAAGTAGGCTGACACCTGACATTGTCTCTG ATCTTCACACGTGCAATGGCATAAAATCCCCACATTCACGCATACGATCGCACACATACACGTGTGTACACACACCATACACACCACACAGGCACAA CAATTAAAAATGCCAATAAATATATCAATCAGTTTCCCTGTGGGGGAAAATGGGTGTGGTCACAAAGAATAAAAAAAGTAAAATAAAAATAGGCCAG GCATGGTGGCATATGTCTTTAATACCAGCACTCGGGAGGCAGATGCAGGTAGATCTCCATGGGTTCGAGGCTAGCTAGGTCCACAGAACAAGTTCTA GGACAATCATGGCACTGACAAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAATAAATAAATAAATAAATAAATAAATAAAATCTCTTCTTG GGGAACCAGTTTGGATAATCACTTAGACTTGATGTCCTCCTCGGTTAGTAGAGAAAGCCGAGGGGCTCCAGGCACCCTCATATCTAGCATCTAGGTC CTGTGATGTTTAGCTTAAGTACTAAAAATAAACACTCAAACTTTCACTTCGTGGTTGTGTCACTGAAGCCTTGCTGGCCGGACCGTTCAACAGACCT CACCCTGGCTGCGCAGGTGTATGTCGGGGCTGCCTGGCGGCTGCTGGGACAATAGCCACTGATCAAGTTCATACTGAAAGGGAGACTTTTATTCAAA ACCAAGAGAAGGATGCAAGTACACCTCTGACTCCCGAGCCTCAGCCTATCTCACCCCACAGCAGCCACCCAGGCGTGCTTGGCACTCACAGATGTAA GCAGCTCCTCCCTGAGTCTCTACAAGGCACTACTACCAGGGGCTTTCTGAAGGCAAACGACTCAGTGATTCAGGATCCTATGACAGCCGAATGTGGT TATCACATACCTTGTGGCCCAGGAAGACTCTGAGGGGTGGGACAGGAGTGGGAGGGGCTCTGGAACAACTTAAAAGGGGCTCTTACCACTTCCTCCC TGCCAGAGAGGGCTAGCTGGAGAGAGACAAGAACCAAAAGCACAGCCTTCCTGTGTGATTTCTACAGCCCCCAGAGCACCATGGACCCAGGTAAGTA AGCTTTCTCTTAAGAGAAGTCAAAACTTCTGACACAAAGCCAGACTCTAGGGCAATQAACATGCATGGGGGATAGGGGTCATQGQGGGGGGGGGGAG TTTCCCAGAGCAATCAGGGCAGTTGGTGTGAACTGGTGGCTGCTTTCAGAGAATGCCATCCCGTTGGATGAGGCATTGGAGAGAGGATGTACCTGCT CTTTCAGACCCAGGGGAAGGAACAGCTGTGGATGCCAAGACAGACACAGGCATAAAGTTGGGTCCTCTCAAGCAGCAGGCAATGAACAGCCTGGTAG ACTGACCTTGATGCCTGGATAGAACACGTTCTCAGCTGGTAGGGATGGGTGATGTTCTCTGGCACCTCTGGGGACTAAGAAAATTCTCTTTAGAGAG TTCAGGACACCCTGCTCCCACTCTGGGTCCCTCCTTTCTGTCCTGTTAAACCAGGATTTGAATCTCCTTGCTCACGAGAAGAGTGAAACTGATGGAA ACTGTGCTGTGCATAGTGCAATACAAATACTAGCTGCCACCTCTGCCTCTTGTTGTCTCTGCCTGTCATAGTCTGTCTGTCTCTGTCTGTCTGTCCT CCCTCCCTTCCTCCCTCCTACACATCCCAGGTTTTGTGCCTCTTGCAGGTTAAAGGGTGAATGACTAACATAAAATTGAGTGGCCCAGGGGGCACTC CACGTAGAGAAACTGTAGCCAGCACAGCACAGCCCCTAAAACAAAGCCCACACACCACAGCCCTCTCTATAACAAGCTATTCTACCAGGCAAGCCTC AGTGTCTACTATAGCAAAGTGCCAAGGGGAGTCCAGCTCCAGACACCCCAGTTACACATCTTAAATCTCGGCTGCAGAGTCAGACTCGGCTGGGGCT GGAGGGGCCAAGTTCCTAGAGTTCCGCTCACCAGCCTCAAAGCCACAAGGGGTTGACTTTAAAAAGTGAAGGTTCCCTGGTGCTGTCCTCACACCCC CTCCAAGCCACACCACAGCCAGCAGCATCTTTATCTGTCTCTCCTGCCCAGCGTGCATTGCACCCTAGATCTAGATCCAGCTGTGGAAGGTATATAG TGGGGTCCACCTCTGCTGGCTATGAACTCATGGGAAGCAGGATTTTGTTCTTACACCTCTGCCTCTCAGATGTTTTGGGTGTAAGTAAAAAGTGTTG ATGGGAGGGAGGGAGAGAGGGATGGAGGAATGGATGGATGGATGGAAGGATGGATGGATGGATGGATGGATGGATGTGTGGATGCATGGATGGATAG AATCAGCCTCTCTAAGTATATTTTAGAAAGCAAATATCTATTCCAGCTTCTCCTCCCACCTGCCTGCTTTCTAAGCCTACACCTCAGGTATCTACCT CCACCAGCCATAGTCTCAGAGAACCCACACCATCCACCAAAGATCTTCTCCACCTTCCTAAAATGTGGCTCCCAGAATAGGGAAAGGTTCTAAATTT ACAGCATTTGCCAATTTCCATGGTGTAAATTTTACCATCCCCAATTGACCTTAGTCGGTCCCATTAAAGGTCTAAATGTTTTGACACAAAAGGAGAC AGACACCTGCCTTCCTTGGCACTTGGGACACTATAGAGTCTCTCCTGAACTAGGTTTGGGGATGTAAATGCATGGCTTTTGATACAGGGGGTGGGGC AAACTCTGGTCCTGGAAGAAGAGATAGTCTTGCTTTTTTACTCAACTTAAGAAGCACCCTAATAGCTAACTCTGAAATGCTGGTGTGAGGGGAAACT GCTTAAGAAGTTTTGCTCAAAACAGGCTCCGGCGCGTTGGAAGGGCGGGGTGGGCCACAAACTATCTGTTTTTCACTCTTTGTCTACCTAGTAGGGA CAGGAGGTGGGTGAGAAGGCCTAGGTTTCTGTTATACAAAATGAGAAACTACAAACCAGGGCTGAGCTGGCCTCTTTCATGATTTGAATGAGCAGCC CTGATATACCCTTCCTAACTTCAAGACATGGGACCACAGATCTCAGCACAACATCTCAAAATCAGAGAAGGGGAGGGGGTGACAAATGAACCCATAA GAGACTTGTGTCTCACAGCTCAGCTGTAGATGGCAGTAGAAGAGAATTCAGGGTCATTCTCTTGTGGCCCCTCCAGAACCTGGCTGTGGAGAACACT GGAGCCCAGAGTAGCTAGGAAAAAACGCTCCTCTGTGTGGTATTGTCTTCCAGTCATGTGTCACTCATTGAGAACTTCTTGAATACAGAGTCTGGTG GGGAACGTAACATGTATGTCAACACGCAACACCAACAGTGAGAGACACAGCACTCCTGAGGGGGCATAAGGACAAGATTCAAAAGCAAAAAGCAAGG CTGTGAACACGTGTCCAGAAAGCATGGCAATTGTATTTTGAAGGGTGTGTAGAAGTTGTCAAACCTAATAAAGAAGGGCCAGGTTGTAGCCAGATCT TCAGACTCTACAGCCTTAAGCCAACAAAGTAAATGAGGCATCCGAGTGTCAGGAACGTGACTGGCACACAAGCCTGAGGAACCTGAGCTTGTAGCCT CAGAGTTTAAAAGCTGGCTGTAGCAAGGTACACACGTAATACCTAAGCCTGCTTAGGGAGGCAGGAATAATAAGACTTGCTGGCCAACCAGTCTTCA GAATTGGCAAACTCCAGGTTCCATGAGAGACACTGATGTCAGCCTCTGACCTCTGTATGTGTGCACACCCATACATATATGAGCACACACCTTGAGC TCATAGTCAGTCAGCTCTGGTGAAGGCAATAGAGCAACAAGGAAGGGGGAATGGTGTCAGCTGATGGGAGTCAGGGAAATAGATGTGCCAAGAAACA AGCTAGACTGGGGTGGCCCTTACAGCGCTGTGTGACAGCACCAGGGAATCCATACACCACCCTAAAAAGAATGGGGGCCAGCAAAGGTCCCCCACCC TTTTCCAAATACATCGGCAGATAGATGAAATGTG~GTTTTGGAAGGAGTAGGGGACAACAGATCCTTGTATCAGGACAGGGGAGGGACCAACATCAA AAGATGTGGAAGATCGAGATGTGGAAGCAACAGACACGAGTGGCCAGAAGCAGTAGAGAGAGCAAGAGTGGCCTTGATCTGTGGAGGACCCTCCACA CCCAAGGCTCATCAGTAATGTCACATGACTCAGCCATTAGAACCCAGGCTAGATGTTCCCCTTTCCCATCTCTGATCTATTGTTTAATAGCTATGTG AATCCAGAGGAACGACATAACATCTCTGGGCCTGTTTCCIAGAATACAAAAGGAACTTACAAGATGTTATGAGGGGGGAGAGATGTAGGGAGAGGAG CTAGGAGTGAGGTGGCCATGGCCAGGGGCTGGGTGTCCTTAGGGAAGCCTTGTGCTGACAGTTCTTCCGTTGGGGCTGATTGTCACGTGGGGTCTCA CAGGGTATCCATTGAGGACGGGGATGGCAGCGCCTGTCTCACGTGGACAGCGCACTTCACTGAAAGCTCAGTGGGTGCCAATTGCATCACTGAGTGA CAGCGTTGGCCCTAATAACAAGATCCCACCAGCTCTCACATCCCTGCCTCCCATCTTGCGGGCTGGGTCCCTGCTTTCAGCCTCTGCCCTTTCTCAT GTCCCCTACAAGCGGCTGAGAAGGTCCAGAGAGAAAATCATCACCTQAGCTGTCTCTCGGGCCAGATGATAAGCAGCCATGGTTTCCTGGGCAGCCT GGAGGGACTGGGGGAATGTACAGATGGGAGCTTTAGGACCTGAGCAGGAGGCGACTGGCTTCCCAGGCTGGGAGCTGGGGQCGGGGGAGGGAATTGA GTGTCAGGCTGAGGCAGGGCAGGGCAGGGGAGTTGGGATGGTGTCGGGCTAGAGTGCTAGGGAGTTTTCCTTTCACCTTAATCATTCTGCAAACCCA AGAACTCAGGAAACACCGAACACCTCAATCAACAGCTCCCCCACACTGGCATTCCCAACTGCCCGTAGCTCAAGAGCAGTTGCTTTCTGACTATTGA GTCATCTGACTCACCAACACTGACCAGGTCCCTCTGTCACCACACGTTCAAATTCCCCCAAATTCTCCTGTTAACTGCCTTGAACATGGCCTGTCCT GGATCTACAGGACCCCGACTCACCCACCCAACCCCCACCCCCAACCTCATATCCAGTATCCCTGGAATGAGACATCAATTTTGTTCACACACCCCAG AGCCCCTCCGGGTTTGTGGCTACAAAAGAACCGGGACAGAACCCAGAGTAAAACAGAAACAGTTCTTGTTCCTTAGGCGTTTCTCCACGTCCCTGAC AGTCAGATTGGGCTTTCTCTACAGTAACCGAAAGCCGTTGATGGGTTGAAAGAAACCTCGAACGCTGAACCCCGAAATGAGTCAGGGAAGGGCGGGC TGTGCATCAGACCCTGAAAATCCTATAGTTGAGAATGGGCATGTGACCTCAAGCTCGTGGGGTGGGGGTGGGGTGCCAGGGGTAATTCAGTTGGGGG GGGGAATGTGTGAGAGAGATGAGCTGTGAAGCCACGTGGTCATGTTCCCCTTCCTCTCTCCAAACGTTCTAGTACAAGCTGATGATAAGGGGACAGT GGCTGTCTGTCCCCAGAAAAAGATGGAGCTGGTGAGGCATGGGCCCCACGCTAAGCCTAAGCGTCTCTCTATCTCTACAGCTAGGATTTCGACTTAT GGTTAGGGATTTAGGAGGGAGGCAAGATAGGAATAGAGGGCAGAGTTAGCTTCAGTAAGACGTGCTTACATAGCATGGAGGAGAATGTAGAGGGGAA AAACGTTTGTCCGGGTCACCCTGATGCCCTTCCTGCCTGTACTGAGTGACCAAGCGTAGCCTCCCCAGCCTGGAGTACATGTCAGGTACCCTGGGTG TCATGTAGCCTAGTCTCCAGCAGGTGGTGCTATGGCCAAGGACAAACAACATCTGCGTTTGAACTGTTTCCCTGGCCTCAAGAGGTCCCCCAGACTC AGATTGGGGAGCAAAGTCCTACTCTGGACTGCAAGACCCATAGGGTCTGACTCTTCCTGTAGATCTGAAGAACTTGGATTCAAGGGCTGGAGAGGGG TGCCAATAGCAAAAGAAGGCGGACAAGGGTCCCCAGGGGTGAGACGGGAGTATGTGGGGTAGAGGTCTGGGGTGGGGGGCATAAGATGTCTGCAAAA ATTACTTTTCCAGTTGTCCTCTTGCTTAGCTGTCAGGAGAAAATACAGCCCAGGCTGGCTCAAGGCTCAGCTCTGAGCAGAATGAGGAGTGGTCGCT GTCATATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTGGGCAGCAGGCCAGGTGTTCAAACACACAATCTGGTTCTGATGTTCTCTTTCAGCA AGCCCGAGGTGCCTGGAGCCTGGGATAAAAGTTCCCAATGGTGCCCCTGCCCCACCCCCGAATGTCTCCTTAATCACCGAGCAATTTTTACCGGGGC GGTAACATCATCTCCTTTGTCTCCTCTAGGGAAACCCAGGAAAAACGTGCTGGTGGTGGCTCTCCTTGTCATTTTCCAGGTGAGGCTTCCTGCCAGG GCAAGAGCTCTCTTCCCTCCTCCACACCCCCTCCCCAGCCAGGAGTGCTGGAACACAAACAGACCCCGCTGCAGGAACGAAAGGTCTAGACACAACC CACCTGCCGTTCACGGCCCCTTGCCCCCCCCCCGCCTCCCCCCCACGAAGGGGGCAGGCATTCTCTGGACTTCCATTGTCCCCCTTTAAAATAAAGC CCAGGGAGACGTAACCTACCCCCACCCTCGTTCTTCCCAGCTCCCACCTCCTCACTCAGGAGACAGAAACAGTGTCTGAGATCTCTTAGACTTGTGC AACACAGGGCTTAGAGTGGGCCTGGTTTTGCACATAGGTGCACACATCATCTGTGAACTGAGAAAAGGACCCTCGGTCGGGCGCTCTGGTTACTCCC CAGTCACCCAGAGTTGCTTCCTCTTGCCTTTCAGTCCAAGGGTCTCCTTGTAATCTCATTCTGTTTTCCTTCATAAAATAGAAAGACCTTGGCTTGG CTTGCCTGTGGGGAGCAGGAGGGAGAATGAGTGGAGCCCGGGACCCGGGTGGAGAGGACGGTGAAGGGAACACATAGTGGGTCTGAATTCTGCAGAG CCAAGAGCCCACTCCGTTCTCTATCCCAGCAATGGAGGCAGAACGTGTGTTCCCCCAACCACCAGAGTCAGGAGAAACTCTGAGAGTCAAGTTTCCT CAATTGGGGTAGGACTCTCTCAAGGTGGGGAATGGCCACGGCCAGCCTGGAGAAGCAATGCTTCAGGATTTGACTTTCTCCCAGGTCCGGAGGCCAG AGGGGGAGCTTTCCAGGAGCTCAGGCCAGGCACAGGCCCCAGGCTGGGCACTGTTCCCCAAACCCCTCTCAGAGGCCCCCTGGAGCTTGGGTTGCAG CCCCTTAGCCTGGCCCTTTCCCATCACCACTCCCGCCCCTCCTGTACTGCTGGCTGGAAGGCCAGAGAAGGGTAAAGACATCTGTGGCTGGTTTTTT GTCTTTCACTTGGGAGGGAAGGGGGGGGGGGGTTCAGACAAGGCCGGATGTGGTGGGGCTGTGGGCTGCAGAGGCGGCAAGCTTGGGGGAAGGGGTG TTGAACAGGAGGGAGAAGAGAAGACTGGGAGGGAGGTGGTGTGGGAGCACACTTCATAGAAGCTGGGAGTTCTGACCTCCAAAGGGTCTAGAAGCCC TTTAAGCCTCTGGGGCCGCAGACCTAAGGCCACAGACCCATTCGTGAAGAGCCAAGCGCAGCTAACCTCTCCCAGGGCCCCCAGGCTGCAGTCAAAC CTGGACCAGGGAAACAAGGTTGCTATGGACTCTTCTTCTCAAGTTAGCCATGCCCCAAGAAAGGGCTCCTGAACACCACTTTGTCCTTATCCTGTCG GTAGGCTCACAATGGTGGTGCGATCTGTGGATCACCACTGAATGACTGAAAATCTCCTACCCAGAGGAGGAACCCTAAACTTTCCAAAGTGGGCCTT CAAACCACCCCACCCCCCTCCCATCTGTGGTGGTCCATCCATCACACACAGGCAGACGGCAGGCACCCCCTCCATTGATAAAAATCACAGCAGCTGC TGAACCGTCCCCCACACGCACCCTGCAGCCCTGCTAAAGGGCTAAAAAAAGCCCAGAACAGCTGAGCCCTGCTGATTGGGATCTGCCGGAAGAGAGG CAAAGAGGTGTGGGAAGAGGGTGGGAACACAGGGAGAGTGGGGGGGAAGAGAGCCGCTTCCTTCCAGGGGCACAAGCCGCCATAGGAAGGCAGTCAC ATTTACCCAAGCACTACCCCACAGGCCCTACGGTACATTTGTCTACGCGCTGAGTGTAGTGGGTACCAGGGAGCTGTGAAAATCCCCATGTCTCTTA TCAGCAGTCCCTCGACTGAAGTTTATTCCTACAAAGGAGCTTTGATCTTCTCTTCCTGCTTCGGACCTTCCTCAACCTTGAACCTAACATAGGGGGT TGTTTTTTGTTTTTCCCTCGAAAGCTGAGGCATTTTGTAGCCCCCCACCCCCAAAAAGAAAACTCTCCTGGGACCCAAAAGAGGCTCCAGAAGAAAG ACACACTTTCCCCCCACATCACAGGGTCCCAAACCCCACAACGGTCCAGCACAGGAGTTGCGATTGCCTCATATCTCCCAGACACAGAGAAGATGTG CGATTTCCAGCTCAGGGCTCAGCAGACCCCAAAGCCCCTAGACTATCCCCAATCTCAGCCAGTGAGGATGAGACTGGATGTCCCAGGAGTTGACAAA CATCAGGCCTTTGCTACTGATGAGTAGAAATGTAAACTTTCTGGTCCTGCCTGAGTCTGCAGGGCCAGACGTTTACATCTTAACTAGATCCTCCCTG AGTAATTCATACATGTGCTAACATCGTTACTTAGATTTATTTTTTGTTTTGGTTTGGTTTTTGGCTTTTTAAGATTTTTTTTATTCATTGAACGTAA ATGCATACACTGTAGCTATCTTTTAGACACATGAGAAGAAGGTATCAGATCCCATTACAGATGGTTGTGAGCCACCGTGGTGGTTGCTGGAATTGAA CCCAGGACTTTTGGAAGAGCAGTCCGTATTCTTAACCCTATTTAGGATTATTTTATTTTATGGGTATAAACATTTTGCCTGCGTGCATAGAAGTACA CCACATGCACAGAGGAGGTCAGAGTTGGGCATCAGAGCCCATGGAACTAGAGTTACAGAGAGCCACGACGCACCGTGTGGGTGCTGGGAACCGAACC GGCCTTCTCTACCAGAGCTACACGCACTCTGCTCCTTAACCCCTGGCCAGTTCTTCAGCCCCACATGCTGAGGCTTAAGAGGTGTGGATTTCTAGTC AAAGACTCACTTGGGGTTTGAGGGGGAAACTATAGTTTCCTGGGCTCCTCCGTCTAAGATGCTGACCCAAAGGGTCTAAGGTCTGAGAGTCTGCAAG AGAACAGAAGCCCCGGGCAATGTCCTGACTGTGAGATCCGGACTGTGAGCTCATCAGGTGCTTCCTTCCCCCTTAGGTGTGCTTCTGCCAAGATGAG GTCACCGATGACTACATCGGCGAGAATACCACGGTGGACTACACCCTGTACGAGTCGGTGTGCTTCAAGAAGGATGTGCGGAACTTTAAGGCCTGGT TCCTGCCTCTCATGTATTCTGTCATCTGCTTCGTGGGCCTGCTCGGCAACGGGCTGGTGATACTGACGTACATCTATTTCAAGAGGCTCAAGACCAT GACGGATACCTACCTGCTCAACCTGGCCGTGGCAGACATCCTTTTCCTCCTGATTCTTCCCTTCTGGGCCTACAGCGAAGCCAAGTCCTGGATCTTT GGCGTCTACCTGTGTAAGGGCATCTTTGGCATCTATAAGTTAAGCTTCTTCAGCGGGATGCTGCTGCTCCTATGCATCAGCATTGACCGCTACGTAG ACCATCCAAGTGGCCCAGATGGTTTTTGGGTTCCTAGTGCCTATGCTGGCTATGAGTTTCTGCTACCTCATTATTTTCCGTACCTTGCTCCAGGCAC GCAACTTTGAGCGGAACAAGGCCATCAAGGTGATCATTGCCGTGGTGGTAGTCTTCATAGTCTTCCAGCTGCCCTACAATGGGGGTGGTCCTGGCTC AGACGGTGGCCAACTTCAACATCACCAATAGCAGCTGCGAAACCAGCAAGCAGCTCAACATTGCCTATGACGTCACCTACAGCCTGGCCTCCGTCCG CTGCTGCGTCAACCCTTTCTTGTATGCCTTCATCGGCGTCAAGTTCCGCAGCGACCTCTTCAAGCTCTTCAAGGACTTGGGGCTGTCTCAGCCAGGA ACGGCTCCGGCACTGGTCTTCCTGCCGGCATGTACGGAACGCGTCGGTGAGCATGGAGGCGGAGACCACCACAACCTTCTCCCCGTAGGGGGCTCCC CTGCCCGGACTACAAGGACCTCTCCCAGGAGCCTTAATGTGGTGCACACATGCACAGACTCTCCATCCACCGAATTGCTGCTGAGGGAAGAGCAATT CTGGCCAGTCAGGTTGACATGAaGACCTAAGAAACTGCTTAACCCCATCCCACTTATAACTACCTCAACCAAAGCTGTAAAAGATATGGCTGAGAAG TTAACACTCAAGCCAAGACAGCTATCCCCAAAACGACAGCCAAAAGTGAAAGTGAGAGGCTGCCACACTTTCCGGAGTGAGGGATGTGGGGCCAGTG AACACCCTGGTTGAGTAGTCTTCGGAGGCCTCTGAATGAACCTGCTTCTAGCTTAGAGAGATGTCCCGGAGATTCAAGGACAGAGCTTATCTCCACA CTTAGCAAGCAAGCAAGAGATGACAGTCTCTCTAAATGCTCCCACAGAGCACCCCTGCCCCTCCCTTCTGCCTCTCCACCGCCTTTCCTGAGGTCCA GGCCACACCATCAGCCTGAAGGCAGTCCCAGCTGGGGCTCTGGATGGCAATGACAAGTAGTTGGGTCTCTATGATGGGAATAAAAAGGTAGGGGAAA GGTGACAGAAAGGAGAGAAGGTGACCCTGCTGGCTGACAGAGGCCAGCAAGCTACTTCTTTGTTCTCTGrCAGCCACTGATACCTTTCCTCATGTTC TGCTTTTGATTCATATATCTTTTATGAACAAACAAATAAAAAAAAATTTTCCCTCGAGGAAACAACTTGGAAAGAAGGGAGGAAATTCCTTGGTTAA ATGGCGAGTGAGTGAGTTGTCCCCCCATTCCACCTGAGAGTCCTGCGCCCCACACCCCTCCGCCCCAGCCTTCCTTTCTCAGCACTCAGAACCATGA GGTCACAGAGCCTCTCCGGAGATGCAAACCCAGGAGGCTGCAAGAGGTGGAAAAAGAGCGAAGACAGGATGTCTGTCTTGCACATACACCTGCAGAG CCCGTGGGATGGGACCTAGGCCCTTACAGGCAGCAGTATACATAGGAGAGCACTCTGAGTATGGAAAGACGAGGTTGTCCCAGGAACTCCTGTGTCT GGGAACTCAGAGGAACCCCGGGTTGGGGGGAAATGGACACCTGCATCCTGTTGTGTTTGCTGTAACAGaATAGCCCGGAAACAGCCCTAACTCTTGT CAGGCCCCTTCAGACTTGCGTACATTCCTCTAAGAACTCCAGTTTGGTGGGAAGCTCAGACAGAGGTCATGACATTCTAGAGTAAGGGAACTAGGGA CTAGTCAGATGCCACAGGCTGGATGGGACTCTGCAGGGTGTTTGAGAGCTAGGACCACTCGGTCCCCTCCTTTCTACCCACTAGTAACAGAAGTTAC TGTTACCAGCCTGACCCCTAAGTGCCTCTGTAGTGCGAGTCTCAGTCCATCCCCGTTTCCTGTAACAAAACACTGCGGTCTGCGGAACTTATACACA ACAGGAATCTATCTCTCACCATTCTAGAAGTTAGACAACTTCCACTCTAGTATCTCCCAAGTCCATTTATAAGGCCTTAAATCCATTCATCAGGGTG GAGCCTTCACGGCCAGCCAGTTATCTCTCAACCACCCCACCCTCCAATACCATCATCCCCTAGGGTTCAAATTCAAACACAGGCCTATTGGAGGGAC ACACACATTCAAAAGACAGCGGTGTGGAAAGCAGAGGGAGAGGGCCAGACTCTGTCGCCCCTCACTCCATCCCCACAGGCCAAGTGTCCTTGTCATT GTGTCCCAGTGTCTAACCAAAGCCCTAATTTCCCCAAGCCCGAGAGCTTGGTCCAAACTATGATACCTGGGCAAATGTCCAATGGCTTAGCACCCGA ATAGCTCTGAGCCTGGCGGTAGGATGAGGGTGGGGGGTGGGAGAAAAAAGGTGAGACATTCACACAAAAACATAGTTCCAATCCCCCCCCCCCCAAG AAAAAAGAAAAATGGATTCCTGTTCCATAACAGTGCTCATTCTCTAGCTTGTAACCACAAAACACCCATTACCCTCCTCCACAGGATGCATGGGGCT AGAAAGACTTTAACACAATTTGTCAGGCGGCCTCCCGGTCTGGAATCAGCATCGTGGGAGGAACGAGGCTGGCTCAAGTGCAGGCAGTGGCTGGTGG CGGGTGGCGGGTGGCGGGCAGCTTTCGGGATGCTGGTACTGAATATTAAAAAGGTTCAGTTGCGACTGTGGGACCACAAGCACGCTGCAAGAAGGCG ATGCCACTGGCCACGGTCATCCCCAAGGGGAACCTGCCAGAGTGCACGTGGCTTTGTAGATCCTAATGAAGTTACAGATGGGAAAACAGCCCTCGAT TCCTACCAGGGAGGAAATAATGGAGGGATCACGGAAGGGGAAGCTGGGCCAACCACACAAGCATGCCACCCTGGCCTCAAATACATTGCGCTAGTAT AACTGGACATCTCCAAATATTTACAGAAACAACAGAACCCCCAGCAATGCTAATTCCCCAAACTGCTGTGTCTCAGAAGTTCTATCCTCAGCTTCAC GCTGGCCTGCTGCCTAAGACCTGGCCTGATGCACTCTTGTGCCTACCAAGGGTGATCCCCAGGATACAAGAAAGCACCCTGCCTGAAGCCCACCCAG GTCTTCTTTCTCATTCTGCCCTTCTCGTCTGCTCCATACAACAGCCCCATGCCTCTAAATCTGTGTCCCTTGCCACGCCATCATTCTGCAATTGCCC CAAGCTCCTTCCAGTCCACTAACAGTCCCTTGTCCACGCCCCCCACGCCCAGTCCCANNNNNNNNNNNNNNNNNNNNCACACACACATCAGCCCTAA CTCAGATCCCCCCTGGCTGTGACCCTAGGCCAAATGTAAGACATTCCCAGGTCATGAAACTGCCCTTTCTGCTAGAAGTGCCGAACCTTTAATAGGT TCCTGGAGACCTCAGGAAGCAGGGGCTGACCCCTGTCGTTCTCTAGACAGAGCAAGGAGCTGGCTGGTCCAAAGAGACACAGCAATGAGGGGAGGTT GCTTAAGCTAGCTGTGGAGCCTGAGGGTCTGGCAGAGTTGCCAAAAGGGGGGATGGAGCCTGGCCTACTCTGAATCCCAACCCTGCCGCTCCCCAGC TGTGTGACCTTCAGCTGTTGCTCAACTGCTCTGAATCTCAGATTTCTCAATTGCAAAACAAGGGAGATTTGGGTAAACACTTAGCACAGAGCCAGAA TGTTGAGCGAGGCAGCAGCAGGGGAGCTCCCACTCCACAGCCAGATGGCCTGGTTCATGTCTCCGCTCCCTTACGGTGCGGTGCCTCGGTTTCCAAA CCTGCATAATTGGAGTTATTAGTCGTGCCTGCCTCCCAGGATTGAGGTAAGGAAGCAATTTTTTCTACAAGCAAAATATTTAGAAATACCCGGGCAA GTGATATCATCTTTTGGGAGATAGTTGAGAAATTATAGATTTAAAACATTGCAGGGATGGAGAGGTGGGTCAATGGTTAGAGCACTGGCTGCTCTTC CAGAGGACCCAGGTTCAGTTCCCAGAATCCAQATGGCAGCTATTAACGGTTTGCAAATCTAGTGTCAGATAATGAGGTACAGTGCCATGTATGTGTG GGGTACATGCCTACATGCAGGCAAGACACTCATACATATAAAATGAAAATAAATCTTTTGTTTTGTTCTGTTTTCATTTTTTGGAAACAGTGTTTCT CTGTAGAGTCCTAGCAGTCCTGGAATTGACTCTCTAGAAGAGAATGGCCTCTAACTCAGAGATCCATCTGCCTCTGTCTCCCAAACCCTGGGGTTAA AGGTGTAGGACACCACCCACCGGCATAAATAAATATTAAAAAATAAAATAAAAATGTTTCTTTAAAGAGACAGAGAGAGAAAAGGCACAAGAGATGG CTCAGTGGGTAGTGTTTTGTTGTACATGAGGCCCTGAGTCCAGATTCATAACCCACACTCACAGGCCAGGGTTGGTGTTGCGGACGATGGGAAACAG AGATGCTAGAGCCTCTGGCCAACCAAGTCTAACAGAAAGTAGAAGCTTCAGGCTTCACAAAGAGACCCCCATCTCAATAGATAAGCAATAAGTAAAT GATGGAGAACAGAGGCAGACACCCCAGTGTCTCTCTGCCCTCCACCTGCACACACACGAAGGAGAGAAACTCTTGCTAAGTTCAAGGTCACCACCTT CAGTTCCTCAGCCCTATGTCTGTTCACACGCAATCCACAACAAACTGGAGGACACCTTAGATGAGAGTCTGGTCTCCCCACAGGGTGGCCAGGAGAG ACATTTGAGGCACAGGAGAAGGAGATCACCTGAGGTCTCTAGGGGCCTCTCTGATACTCAGAATCCTAACGCCCTTTAGGTCCACCCTCAATTGCGG TCTGCCAGCATCCATCCTTAATACGAACQTCTCTTGCCTGCAGACAGCTCTTGCCTTGATAATGAGTCTTCTTTGAGAACGAGGTACTCACTTGCGG GTTTTTTGAGTCAAGGACAGAGTAGGTAAGGAAGAAACAAGCCTATGAGATGGTGGGAAAAAAGGACAGAGTCGTAGAGGAGATTCTGAATTCGGAG GAAGGAGCAGGGATGGGGGAGCTGTATATTGGAGACGAGACATGGAGAGTATATCCAGTGGGCAGATGAATCCGTGTGTGTGAGTGAGTGAGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCCTCCCTCAAGTCTCTAGTCTCACAGGAAGAAATGATTCCATGGGTGTTTGTTCTT TTCAAGGGAAAGGTTAGCCGGGGTGTGGTGGCGCACGCCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGGCGGATTTCTGAGTTCGAGGCCAGCCT GGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTACACAGAGAAACCATGTTTCAGGGAGGGGGAAGGAGGAAGAAGGTCAAGTTTCCCTACACTGA GTCCCTGAGGACTCTCACTCTCACCCCAACAGGAACCCAGCTTTTCCACACACCAGGCATCCCAGCCAGGGACACAGATGAAGGCACTGTCAACAGA AGCACCAGCTAGAACTTCTGTGATCCTGAGGTCACATGGCCCAGAGGTTCCTCCCTATTCTGATTTGTATTTGTGACCCGATCATTTCCTTGCAGAT GTTAGGTTTACCCCTTCCCTTGTGCACTTTGAAAATGGCTACTGCCAGCGGGGGGGCGTGGTGCCGCATGCCTTTAATCCCAGCATCAGAAGGCAGA GGCCAGCTGATCTCTGTGATTTTGAGGCCAGCCTGGCGTACATAGTAAATTCCAAGATGCCCAGGAGAAAAAGGAAGGCAGAAGCAAATGGCTATCG CTCTATTTGTCTACTGCCCACTGATCCCACAAAGTTCCCTGACCAGCGTGTGTGTGGCACTGTGTCACACACCACAGTGACCCACGAGTTCTCATCT CCCAGTGTGACCTACGGGTAGTCTGCCCTGAAGTGGATACCCAAGTCCTCTATCACGAGGGCAGGAGAGGGACTTTCTCAATCCATGTCACAGCTTG CCTAGGACAGTGTACGTTATGTTTGCTCTAAACAAATATCATTGTGAAGCTGAACAGATGTTGCAGATAAAATGCCCTAAACCCTTTCCCTACGTTT CAAAGAAGCTGGGAACTCAGGCGTGCTAGTCTTGGATGGTTTCTGCATCTGTGGTCCAGTAACTGGCACGCGCAATCTCTCTTGCAAAGGCAGAGGT GAATTCTTCTGGCCCCGGGGGTGTTTTCTGCAGCCTGGCTAGCTCCAGACCTGTAATTAAGTCTAGTGGTATGCTGGCAAGGATGTGGAGAAAGAGG AACACTCCTCAATTGCTGATGGGATTGCAAGCTTGTACAAGCACTCTGGAAGTCAGTCTGGCGGTTCCTCAGAAAATTGGACATCGTATTACCGGAA CACTGGTAAGTGGATATTAGCCCAGAAGCTTAGAATACCCGAGATACAATTTGCAAAACACAAGAAAATCAAGAAGAAGGAAGACCAACGTGTGGAT ACTTCATTCCTCCTTAGAATAGGGAACAAAATACCCATGGAAGGAGTTACAGAGACAAAGTTTGGAGCTAAGACGAAAAGGTGTACCATCCAGAGAG TACCCCACCCGGGGATCCATCCCATAATCAGCCACCAAACCCAGACACTATTGCATATTGCCAGAAAGGACCCTGATATAGCTGTCTCTTGTGAGGC TAGGTCAGGGCCTGGCAAACACAGAAGTGGATGCTCACAGTCATCTATTGAATGGAACACAGGGCCCCCAATGGAGGAGCTAGAGAAAGTATCCAAG GAGCTGAAGGGGTCTGCAACCCTAThGGTGGAACAACAATATGAACTAACCAGTACCCCCCAGAGCTCGTGTCTCTAGCTGCATATGTAGCAGAAGA TGGCCTAGTCGGCCATCATTGGGAAGAGAGGCCCCTTGGTCTTTGCAAACCTTGGTACAGGGGAATGCCAGGGCCAGGAAGCGGGAGTGGGTGGGTT GGGGAGCAGGGCGGGAGGAGGGTATAGGGAACTTTCGGGATAGCATTTGAAATGTAAATAAAGAAAATATCTAATAAAAAAGTCTAGTGGTGGAGAA TCACCCAAGTGGGAACCATCTTTGCTCCTGCACTACAGCTCTCACAGGACTGGTAGACATGCCATCTTGTTCGAGCTACCACCTCTGTCTACCACCT ACCCTGCCCGTCATGCTCTGGCTCTGCTGGGTTGGCCGTTGACAATCTCTGGACTAGAAAGCCTGGTCAGGGAATGAACGCGATGAGAACTCGTGCC TGCTCTAACCACAGTCTCTCTCTCCATCACCCCAGCAGAGCCAACCCTAAGCAGACTACGAACTAGAAGAGCTTCCGAGCTTTAGGTTAAACACAGC AGAGCAGGGGAAACACAGGAATCACGAGGGATCGGGAGGGAGGGGAGGTTTTGAGGAAGGGAGGAAGGAAGGATGTGCTGACATTTGCTTAGTGTCC ATTCTAGGGATCCACCTGTCACTQAATCCACAAGTGAGGAAGCCAAGGGTGAGAGCAGGCTGGTGTAACTGACTCATGGTGACACAGCCAGCAGCTG TGCTAAGATTATATTCCCTACTTCATTTATACTGTGTATTGAAACCTTACCTTATTGAAGTCTGTCCTGTCTGTCTGTC1GTCTGTCTGTCTCTCTC TCTCTCTGTTTTTTTTTTTTTTTTTTTTTTTCGAGACAGGGTTTCTCTGTGTAGCCCTGGCTGACCTGGCACTCACTTTGTAGACCAGGCTGGCCTC GAACTCAAAAATCTGTCTGCCTCTGCCTCCCTCCCAAGTGCTGGGATTAAAGGCGTGCACCACCACACCTAGCCTTATTGAAGTGTTTTAGCAATCC TATTGAAGGCCCATTTTACAGATGGGGAAGTAAAGCCCAGAGAGGGGAAAGTGCCAAAGCCATAAGGCAATAAAACTACTAAAGGATGTCAGCCAGT TCTAGCTGGCCTCCAAAGGCCAATTTGCATCTGCCCTCTTGCTGCACCATTTAACCACATAGTTGCCTACTCTTATCAAATCCAATCAAATGCAGCT AGGAGCTAGGCACTGTGCTGGGTGTACATAGCATCTCTCAAAGCACGCTGGATGCAGAGTTCTGTCCTGGGAGGAGGCACGGTCGAATGAGTACCGC CTTCAGGAAGCAGGGAAACAGCCCGGCTGTGATAGGCTGTCCACTCCTTCTTCCCACTGGGCCCTGCTTCTCTCTCAGGCCTTCTTGGGCCTCCTGG CTCTGCCATGGAGCCACTGGGCAACATGAACAAGTCACCTGTCTGCTGCAGCTCCTCTAGAGCAAAAGAAAGTTCCTAGATGGAGTGAGTTTTACAC GTGCCTGGGTGAGGGGCTGAGGAAGCTACTCCACCCCCAGCTGTGGTTTCTGGTGGGGCCACTGGTGGCAGCAGGTGAGGGGAAGTATCTGTCACTC TTCCAACAAAGGCAATCAAACAAAAGCCTCCTGGGGCATTGTGGGAACTGCAGTAAAGGCGCCAAAAATAAAACACAACTTTCCTTTGATAGGCACT GGTAGCTGCCTTGGGGGTTGTGACAAAAGTGTTCAGATTTCACACCTCAGTTCATACCCACACACACACACACACACACACACACACACACACACAC ACCAGTCTCACAAACAAGTCATATAATAGGCAGTCAATGATCCCAGAAGAAACATCTCCGTGGGCTGTGACACATGTCACAAQAACCACATATGTGT CAAATGGCTTGTCCTTTCCATTTTGAAATGTTCCATATTTTAAAAGAACTTTTAAATATCCTATTTTATTTCATGTATATTGGTTTTTGTCTGCATC TATGTCTGTGTACCCTACCCATTCACAAGGCCAGATTAGATTCCCTGGAACTGGGATTATAGACAGTTGTAAACTGCCAGGTGTGTGCCTGGAATCA AACTTGGGTCCTCTGAAAGAGCAATCAGTGCTTTTAAAATATATATACATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTAAAATTTATTTTATGTATATGAGTACACTGTCGCTATCTTCAGGCATACCAGAAGAGGGCTTTGGATCCTATAACAGAGGGTTGTGAGCC ACAGTATAATTGCTAGGAATTGAACTCAAGGCCTCTGGAAGAACAGCCAGTGCTCTTGACCACTGAGCCATCTCTCCACCCCTAAAGTTTTCAGTAT GTTTTAAGCAAGGAGCTGAACGGGGTATTTTGTTCTTTGTCCTTCAAGCTACAGAACCAAACTTGCTAGCATTCATTCATAAATATTCATATGGGCA GTATGCCTAAAAATTATAAAATACTGATAGGCAAAAGTGCATACATTGCCCACACAGCGAGAGGAACAGACACATAGACCCCCCCCCCCCACACACA CACACACACTGGTACTACAGGGGCTCCCCTGTGTACACACACTGCAGTACAACTGCTTCCCCCATAAGGGACATTGACACCCACTCGAAAGGCCCAG AGAGAGCTCAACCACAACCCAGTGACATGAATGGATTGACTTAGCCAGATCAAGGCACCTCGATGGCACTGAAAGGAAGGGCTTAATCTCCTTTACT GTATCTTCAACTGTCACAGCTGGCCTCTCTTTCGGGCTATGGGCTCATCCACCAACCCTTGCAGCGGAGACTAAGGAAAAGGAGACCTTGGGGAGTA TAGGAATCCTTGGGAGGAGAGGTTGGGAGGAGGAGAAGAACATTAGCCAAAAACAGCAGGCTGGGCGACAACGGAGGCGCCTAGTGAACTGGCCTGA GTGGTGGTTCTGAAAGAGCCTGGGGGAGGCGGGGGCAGGTCTTGAACCCAGACAAGTCCGAGCTCCTGCTCTCACATGAACAGCCAATCCCTTGCCC CACTCCTCTTTCTAGCTAGGTGGCCTTGGGCACATGGCTGAACTTGCTTGGCCTCAGTCTCCATCTCCACGGAATGAGAAAGTATTGTCTGCATGGC AGGGTTGTGTGGTGCATGTTGGAAGTTGCGCCTCATCTTCTGGGCTCTCCCAACATTCAACAGTTTGCCTTCTTTCCCGGCCTTGCAATCCGACTCT TGCTTCAGAAACTCCAGACCCCCTCATTAACGGCAGACCTTCAGAATGTGTTTATTTCTTGTCTCCCCACCCCCACCCCACTTCCCAGCCAGATGCA AGCATGGGAGGTGGCCGTAGTTCAAGGCCCACCCTCCCTTCGGGGACTTTCAACGTTCCTCAGTTCCTTTTGATCCCATAGCTCCAGCCACAAGCCA AACAGCCCCCAAGGCCTCCAAAGTTTTCTGCCTGTGCTCTCTACCCCTAACCCCAGTGCTGCCTGTAAGAAACCGTTCCAGGCTCTGCCCAGAAGCC CCTCCATCCTGTTAGGTGATACCACATGCTCAAAGACTGACCCAGAAAAACAATTCTTTTCAGCTCATTGTGATGGTGCACATCTGTAACCCCACCA CGCTGAGGAGGCTAAGGGAGAAAGAGAGAATTCTCGGCCAGCCTGGGCTACAGATCAAGACCCTGTCTCAGAAAAATTCCAACAAAATTGCTGGGGA AATATTGCTCACCATCGGAATGCTTACATAGCATGCATGAGTGCAGNGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNNNNNNGNNNNNNNNNNNNNNNNNNNNNNNNNN MOUSE SEQUENCE—mRNA GGACATGGACTGCTATTCTGCGTCGCCTCAAACAGGAGCTGATGTCCATGAAGGAGGGGGGGATGGCTTGCAGGATCAGATGAACTGCATGATGGGC GCAGACTGGGCTAGCTGGAGAGAGACAAGAACCAAAAGCACAGCCTTCCTGTGTGATTTCTACAGCCCCCAGAGCACCATGGACCCAGGGAAACCCA GGAAAAACGTGCTGGTGGTGGCTCTCCTTGTCATTTTCCAGGTGTGCTTCTGCCAAGATGAGGTCACCGATGACTACATCGGCGAGAATACCACGGT GGACTACACCCTGTACGAGTCGGTCTGCTTCAAGAAGGATGTGCGGAACTTTAAGGCCTGGTTCCTGCCTCTCATGTATTCTGTCATCTGCTTCGTG GGCCTGCTCGGCAACGGGCTGGTGATACTGACGTACATCTATTTCAAGAGGCTCAAGACCATGACGGATACCTACCTGCTCAACCTGGCCGTGGCAG ACATCCTTTTCCTCCTAATTCTTCCCTTCTGGGCCTACAGCGAAGCCAAGTCCTGGATCTTTGGCGTCTACCTGTGTGAAGGCATCTTTGGCATCTA TAAGTTAAGCTTCTTCAGCGGGATGCTGCTGCTCCTATGCATCAGCATTGACCGCTACGTAGCCATQGTCCAGGCCGTGTCGCGTCATCGCCACCGC GCCCGCGTGCTTCTCATCAGCAAGCTGTCCTGTGTGGGCATCTGGATGCTGGCCCTCTTCCTCTCCATCCCCGGAGCTGCTCTATGCGGCCTCCAGA AGAACAGCGGCGAGGACACGCTGACATGCTCACTGGTCAGTGCCCAAGTGGAGGCCTTGATCACCATCCAAGTGGCCCAGATGGTTTTTGGGTTCCT AGTGCCTATGCTGGCTATGAGTTTCTGCTACCTCATTATCATCCGTACCTTGCTCTGGCACGCAACTTTTTGAGCGGTCAAGGCCATCAAGGTGATC ATTGCCGTGGTGGTAGTCTTCATAGTCTTCCAGCTGCCCTACAATGGGTGGTCCTGGCTACAGACGGTGGCCAACTTCAACATCACCAATAGCAGCT GCGAAACCAGCAAGCAAGCAGCTCAACATTGCCTATGACGTCACCTACAGCCTGCCTCCGTCCGCTGCTGCGTCAACCTTCTTGTATGCCTTCACGG CGTCAAGTTCCGCAGCGACCTCTTCAAGCTCTTCAAGGACTTGGGCTGCCTCAGCCAGGAACGGCTCCGGCACTGGTCTTCCTGCCGGCATGTACGG AACGCGTCGGTGAGCATGGAGGCGAGACCACCACAACCTTCTCCCCGTAGGGGCTCCCCCTGCCGCCGGACTACAAGGACCTCTCCAGGAGCCTTAA TGTGGTGCACACATGCACAGACTCTCCATCCACGAATTGCTGCTGAGGGAAGAGCAATTCTGGCCAGTCAGGTTGACATGGAGGACCTAAGAAACTG CTTAACCCCATCCCACTTATAACTACCTCAACCAAAGCTGTAAAAGATATGGCTGAGAAGTTAACACTCAAGCCAAGACAGCTATCCCCAAAACGAC AGCCAAAAGTGAAAGTGAGAGGCTCCACACTTTCCGGAGTGAGGGATGTGGGGCCAGTGAACACCCTGGTTGAGTAGTCTTCGGAAGGCCTCTGTTG AACCTGCTTCTAGCTTAGAGAGATGTCCCGGAGATTCAAGACAGAGCTTATCTCCACACTTAGCAAGCAAGCAAGAGATGACAGTCTCTCTCAATGC TCCCACAGAGCACCCCTGCCCCTCCCTTCTGCCTCTCCACCGCCTTTCCTGAGGTCCAGGCCACACCATGACGCTGAGGCAGTCCCAGCTGGGGCTC TGGATGGCAATGACAAGTAGTTGGGTCTCTATGATGGGAATAAAAGGTTAGGGGAAAGGTGACAGGAAGGAGAGAAGGTGACCCTGCTGGCTGACAG ACGCCAGCAAGCTACTTCTTTGTTCTCTGTCAGCCAGCCACTGATACCTTTCCTCATGTTCTGCTTTTGATTCATATATCTTTTATGAAGAAACAAA TAAAAAAAAAATTTTCCCTCGAGGAAACAACTTGG MOUSE SEQUENCE—CODING ATGGACCCAGGGAAACCCAGGAAAAACGTGCTGGTGGTGGCTCTCCTTGTCATTTTCCAGGTGTGCTTCTGCCTGATQAQTTCACCGATGACTACA TCGGCGAGAATACCACGGTGGACTACACCCTGTACGAGTCGTGTGCTTAAGAAGGATGTGCGGAACTTTTAAGGCCTGGTTCCTGCCTCTCATGTA TTCTGTCATCTGCTTCGTGGGCCTGCTCGGCAACGGGCTGGTGATACTGACGTACATCTATTTCAAGAGGCTCAAGACCATGACGGATACCTACCTG CTCAACCTGGCCGTGGCAGACATCCTTTTCCTCCTAATTCTTCCCTTCTGGGCCTACAGCGAAGCCAAGTCCTGGATCTTTGGCGTCTACCTGTGTA AGGGCATCTTTGGCATCTATAAGTTAAGCTTCTTCAGCGGGATGCTGCTGCTCCTATGCATCAGCATTGACCGCTACGTAGCCATCGTCCAGGCCGT GTCGCGTCATCGCCACCGCGCCCGCGTGCTTCTCATCAGCAAGCTGTCCTGTGTGGGCATAGGATGCTGGCCCTCTTCCTCTCCATCCCCGGAGCTG CTCTACAGCGGCCTCCAGAAGAACAGCGGCGAGGACACGCTGAGATGCTCACTGGTCAGTGCCCAAGTGGAGGCCTTGATCACCATCCAAGTGGCCC AGATGGTTTTTGGGTTCCTAGTGCCTATGCTGGCTATGAGTTTCTGCTACCTCATTATCATCCGTACCTTGCTCCAGGCACGCAACTTTGAGCGGAA CAAGGCCATCAAGGTGATCATTGCCGTGGTGGTAGTCTTCATAGTCTTCCAGCTGCCCTACAATGGGGTGGTCCTGGCTCAGACGGTGGCCAACTTC AACATCACCAATAGCAGCTGCGAAACCAGCAAGCACCTCAACATTGCCTATGACGTCACCTACAGCCTGGCCTCCGTCCGCTGCTGCGTCAACCCTT TCTTGTATGCCTTCATCGGCGTCAAGTTCCGCAGCGACCTCTTCAAGCTCTTCAAGGACTTGGGCTGCCTCAGCCAGGAACGGCTCCGGCACTGGTC TTCCTGCCGGCATGTACGGAACGCGTCGGTGAGCATGGAGGCGGAGACCACCACAACCTTCTCCCCGTAG HUMAN SEQUENCE—GENOMIC AATATATGAAACAAATATTGACAGAATTGTCAAAGAAATAAGAGAAACACATAAAGCAAGAAATAAGAGAAACACATAATTCAACAATAATAGAAAC TTAAATATCCTCCTTTCAATAATAGATACAACAACTAAGCAGTTGATCAACAAGAAAACAGAAGATTTGAACAATGCTATGAACCAACTAGACCTAA CGTCTATCTATAAAACACCACCCAACAACAGCAGAATACATATTCTTCTCAGATATACATAGAACATTCTCCAGGATAGGCCATCTGTTAGGACATA AAACAAGTCTCAAAAAATGTAAAAGAATTGAGATCAGACAAAGTCTGTTCTCTGACCACAACCAGTAACAGAAGGAAATTTGAAGAATCCATAAGTA TGTGGAAATGAATCAAGGAACTCAAGGGAAATTAGAAAATACTTTGAAATGAATGAAAATGAAAACACAGCATACCAAAACTTATGAGATGCAGCTA AAATAGTGCTTACAGAGAAATTAATAGCTATTAATGCCTGTATTTTTTAAAAGAAGAAAGATACCAAATTAAAAAAAAACTTTTCACTTTAAGAAAA AGAATAGTGAACCAAGCCCAAATCAAGCAGAAGGAAGGAAATAATAAAGATTAGAATGGAAAAAAATGAAATATGGAATTGGAAAAACTAGAGAAAA ATTAACAAACCCAAAAGTTGTTATATCAAAAAGATTGATTTAGTTTGATAAACATTTAACTAGACTTACCCTAATATCAAACCACATACAGATATCA CAAGAAAAGTACAGACCAATATCTCTCATAAGACACATATAAGATAGATGCACAATTTCTTAACAAAATATTAACATGCCAAATCCAGAAACATTAC AAAAAAAATTGTATACCATGACCAAGTGATTTATTCCAGGAATTCAAGGTTGGTTTAATATAAAAAAATCAATTCATATAATACACCATATTTAATA GAATAAAGGGCAAAAACACTCAATTGTCTCAGTGGACACAGGAAAGGCCTCCAACTCCCTCCATGTCCCTCCAAAGGACATTATCTCATTCCTTTTT ATGGCTGCATAATATTCCATGATGTATATGTAGCACATTTTCTTTAACCAATCTATCATTGATGGGCATTTAGGTTGATACCATGTCTTTACTATTG TGAATGGTGCTGCAATAAACATACACGTGCATGTGTCTTTATAATAGAACAATTTATATTCCTTTGGGTATATACCCAGGAATGGGATTGCTGGGTC AAATGGTATTTCTGTCTCTAGGTCTTTGAGGAATTCTATACTATCTTCCACAATGGTTGAACTAATTTACACTCCCACCAACAGTGTAAAAGCATTC CTTTTTCTCCACATCACCAGCATCTGTTATTTTTTGAATTGTTGATAATAGCCATTCTGACTGGTATAAGAGGGTCTCTCACTATGGTTTTGATTTG CATTTCTCTAATGATCAGTGTGTTGAGCTTTTCAAAATATGATTCTGGGTCACATGTATGTCTTCTTTTGTGAAGTGTCTTTTCATGTCCTTGGCCC ACTTTTTAATTTTTTTTTCTTGTAAATTTGTTTAAGTTTTTATAGATGCTGGATGTTAGACTTTCGTCAGATGCATGGTTTGCAAAACTTTTTTTCC CACTGCGTAGGTTGTCTGTTCACTCTGTTGATAGTTTCTTTTGCTGTACAGAAGCTCTTTAGTTTAAGTAGATCCCTTAATTTACTTATTTGTCAAT TTTTGTTTTTGTTACAACTGCTTTTGGCATCTTTGTCATGAAATCTTGGCCCGGGCCTTGGTCCTGAATGGTATTGCCTAGGTTTTCTTCTAGGGTT TTTATAGTTTTTAGTTTTACATTTAAGTCTTTAATCCATCTTGAGTTGATTTTTGTATATGCTGTAAGGAAGGGGTCCAGTTCCAATTTTCTACATA TGGCTAGCCAGTTATCCCAGCACCATGTATTAAATAAGGAATCCTTTCGCTATTGCTTGTTTTTGTCACGTTTGTTGAAGATCACGTAGTTGTAGGA GTGCAGTCTTATTTCTGGGTTCTCTATTCTGTTCCATAAGTCTGTCTGTTTTTGTATCAGTACCATGCTGTTTTGGTTACTGTAGCCATGCAGTATA GGTTGAAGTCAGGTAGCATGAGGCCTCCAGCTTTGTTCTTTTTGCTTAGGGTTGGCTTGGCTATTTGGGCTCTTTTTTGGTTCCATGTGAATTTTTA AATAGTTTTTTCTAGTTCTGTGAAGAATGTCAATGGTAGTTTATGGGAATAGCATTGAATCTATAAATTGCTTTTGGGCAGTATTGTCATTTCCACA ATACTGATTCTTCCTATCCATGAACACGGAATGTTTTTCCATTTGTTTCCATTATTTCTAATTTCTTTGAGCAGTGGTTTGTAGTTCTCCTTGTAGA TGTCCTTCACTTCCCTTGTTAGCTGTATTCCTAGGTATTTTATTCTTTTTGTGCCAATTGTGAATTGGAGTTCATGCGTGCTTTGGCTCTCTGCTTG CCTGTTTTTGGTGTATAGGAATGCTAGCAATTTTTGCACACTGATTTTGTATCCTGAGAATTTGCTGAACTTGCTTATCAGCTGAAGAATCTTTTCG GCTGAGACAGTGGGGTTTTCTAGATATAGGATCATGTCATCTGCAAACAGGAATAGTTTCACTTCCTCTCTTCCTATTTGAGTACACTTTATTCCTT TCTCTTCCCTGAATATGACTGCCCTGGCCAGAACTTCCAATACTGTGTTGAATAGGAGTGATGAGAGAGAGCAACCTTGTCTTGTCCTGATTTTCAA GGGGCTTACTTCCAGCTTTTGCCCATTCAGTATAATATTGTCTGTGAGTCTGTCATATATGGCTCTTATTATTTTGAGGTATATTCTTCATTCACCT ACTTTATTAAGAGTTTTTAACATGAAGGGGTATTGAATTTTATCAAAGGCCTTTTCTGCATCTATGGAGATAATCATGTGGTTTTTGTCTTTAGTTC TGTTTATGTGATGAGTCACATTTATTATTTGCCATATGTTGAACCAACCTTGCATCCCAGGGGATGATGAAGCCAAATTTGATCATGGTGGATAAAC TTTTTGATGTGCTGCTGGATTCGGTTTGCCAGTATTTTGTTGAGGATTTTTGCTCAATGTTCATCAAGGATAATGGCCTGAAGTTTTCTTTTTTTGT TATATTTCTGCCAGGTTTTGGTATCAGGATGATGCTGGCCTCACAGAATGAGTTAGGAAGGAGTCTCTCCTTTTCAATTTTTTTGAGTAGTTTCCGT AGGAATGGTACTCTTTTCTGTACATCTGGTGGAATTCAGCTGTGAATCCATCTGGTCCTGGACTTTTTTTGGTTGGTAGGCTGTTTATTACTGCCTC AGTTTCAGAACTCGTTTTCAGTCTGTTCTGGGATTCAATTTCTTCTTGGTTTGGGTCTTGGGAGGGGTGTATGTGTCCAGGTGTATCCATTTCTTCT AGATTTTCTATGCACATAGAGGTGTTTATGATATTCTCTGGTGGTTGTTTGTATTTCTGTGAGGTCAGTGGTATTATCTCCCTTATTTTTTTAGATT GTATTTATTTGAGTTGTCTCTTCTTCTTCTTTATTAGTCAACTAACAGTCTATCTATTTTATTAACTTTTTTTGAAAAACCAGCCTGGATTCATTGA TATTTTGAATGGTTTTTTTTTTATGTCTCTATCTCCTTTGATTCAGCTCTGATTTTGGTCATTTCTTGTCTTCTGCTAGCTTTGGGACTTCTTTGCC CTTGGTTTCTAGTTCTTTTAGTTGTGATGTTAGGTTGTTAACTTGAGATCTTTCTAGCTTTTGATGTGGGCATTTAGTGCTATATTTATTTACTCCT TAATACTGCCTTAGCTGTGTCCCAGAGATTCTGGTATGTTGTATCTTTGTTCTCATTAGTTTCAAAGAACTGCTTGATTTCTCCCTTAATTTCATGA TTTACCCAAAAGTCCTTCAGGAGCAGGTTGTTCAATTTCCATGTAGTTGTGTTGTTTTGAGTGAATTTCTTAGTCTTGAGTTCTAATTTGATTGTGT TGTTGCCCAAGAGACTGTTTGTTATGATTTCAGTTCCTTTGTATTTGCTGAGGAGTATTTTACTTCCGATTATGTGATCAATTTTAGAGTAAGTGCC CTTTTTGAGCCTATGTCTGTCTTTGCATGTGAGATGGATCTCTTGCAGATAGCATACCAATGGGTCTTGGTTTTTTATCCAGCTTGCCACTCTGTAT TGAATATCTTTGTTAATTTTCTCTCTCAATGATCTGTCTAATGGGGTGTTAAAACCTCCCACTATTATTGTGTGGGAGTCTAAGTCTATTTGAAGGT CTTTTTGAGCCTATGTCTGTCTTTGCATGTGAGATGGATCTCTTGCAGATAGCATACCAATGGGTCTTGGTTTTTTATCCAGCTTGCCACTCTGTGT CTTTTAATTGGGGCATTTAGCCCATTTACACTTAAGATTAGTATTGTTATGTGTGATTCTTCCTGTCATTTGATGCTAGCTGGTGGTTATTTTGCAG ACTTGTTTATGCGGTGCTCATAGTGTCACTGGTCTGTGTACTTCAGTGTATTCTTGTAGTGGCTGATAACAGTTTTCTTTTTCCATATTTTTAGTGC TTCCTTCAGGAGTTCTTGTAAGGCAGGTCTGGTGGTAATGATTCCCTCAACATTTGCTTGTCCTGAAAGGATCTTATTTCTCCTTTCGCTTATGAAG CTTAGTTTGGCTGGATATGAAATTCTGTATTGGAATTTCTTTCCTTTAAGAATGTTGAATATTGGCCCCAATCTTCCTCTGGCTTGTAGGGTTTCCA CTGAGAGGTCTGCTGTTAGTCTGATGGCTTCCCTTTGTAGGTGACCTAGCCTTTCTCTCTGCTGCCCTTAACATTTTTTTTCTTTCATTTCTACCTT GGAGATCTGATGATCATGTGTCCTGGGATGATCTTCTCATGGAGTATCTCACTGGGGTTCTCTGCATTTCCTGAATTTTGAATGTTTTGCTTGTCTA GCTAGGTTGGGGAAGTTCTCCTGGAAAATATCCTGAAATATGTTTTCCTTTGTTTCCAACTCCCCATCTCCCCCCTTTCAGATACCCTTCAGTCATA GATTCCGTCTCTTTACATAATCCCATATTTCTTGGAGGTTTTATTCATTCCTTATCATTCTTTTTCTCTATTCTTATCTGCCCGTATTATTTCATAA AGACAGTCTTCAAGCTCTGACATTCTTTCAGAGGAAGATCTTTCAGAGTTCTTGCAGTCTTGGCCTATTCTTCTATGGTTTACTTCTGATTG CATTGTGTGTTCTTGTAGTCTGTTTTTCAGCTCGATCAGGTCAGTTATGTTCTTCTTATACTTATCTTATTTTTGGCTGTCAGCTCCTGCATTGTTT ATCATGATTTTTAGCTTCCTTGCATTGGGTTACTCTTGCTTCTTTAGCTCAGCGACGTTTTTTTTTAATTCCACATTCTGTGTCTACTTCTTTCATT GCAGTGATCTTAGCCTTACCCCAGTTCCAAACCCTTGCTGGAGAGATGCTGCAGTCATTTGGAAGGAAGAAGGCACTTTGGCTTTTTGAGTTTTTAG TGTTTTTATGCTGATTCTTTCTCATCTTTGTGGCTTATCTACCTTTGATTTTTGAGGTGCTGACCTTTGGATTGGTTTTTTTTGTGTTTCTTTTGTT TTTCTTTTAACAATCTGGCCACTTTTCCATAAAGCTGCTGTGGCTTGCTGAGGGTCCCCTCCAGACTCTAGTCACTTTGGATTTTCCAGTACCTGGA AACACACCTGTAGGAGATGGCCGGAGACCCCATTTGGGAGGTCTCACCCAGTCAGGAGGAACAGGATTGGGGAGCCACTGAAAGAAGCAATCTAACC ACACTTCCGAAGAGAAACTATGCTATGCTGGGCACCACTTGCATCCCCAGTTGGCTTGGGATCTCCAAAGCCTGGAGACTGGTGTGGCTAAGTCGCC AAAACAGCAAAGATGGCAGCCTGCCCCTCCCCCGAGGAGCTCTGTCCCAGGAAGTCTTCAAATCTCTGTCAGCCAGAGAACATCGACAGGAGTGGCT GGAGGCCACAGTTGGGAGGTCCTGCCCAGTGAGAAGGAATGGATTAGGGACCCTCTTAAAGAAGCAGTCTGGCCATATTTTGGTAAAGCAGCTGTGC CACGTTGGGAGATCCTTTCAGCCCCCAGTTGGTTTGAGCTCCCCAAAGCTGAAAGGCTGGAATGGCTGGGATGCCCAAACAGCAAAGGTGGCAGCCC TCTCCACCATCCAGGCACCCTGTCCCAGGGAGAGATCAAAATTTTATGGGCTGTAGAAAATGGGCAGAGGTGGCTGAAGGCCTTGTTTGGGAAGACC CACCCAGTGAGGAGGAATGGATAGGAGTCCTGCTTAAAAAAACAGTCTGGCCACGTTTTGGCAGAGCAGCTGTGCTGTGCTGGGGGATCCTTTCCAC ACCTGGTGGGTTTGGACTCTCCAAAGTCTACAGGCTGGAACAGCTGAGTCGTCCAAACAGCAAAGGTGGTGCCCCTCACCCCCACCCCAGCCACCCC CAGAACTCCACCTTGTCTCAGGTAGGTGCTACACTGTTGCCCGTGGCTGGCTGGAATTCCAAGCCAGTTGGTCTTTATCTGGTGAGGGCTGTGGAAG TGAGGCCCACAGACCAATGCTGCTCAGCTCCCTGGATTCAGCCTCCTTCCTAGGGGTATGTACAGACCTCCTGCCTTGCCTGAATGGCGGTCACCTT TGCTGGGGTTCCGGAGCCTGAGTATGTAAAGCTCCTGGGTGTCTGTGCATGCCTGAGCAGCTGCTCTGCCAATAATCCAATGCAGCTCTGTGTGTAA GACCCAAAGGCCTGGTGGAGTGGGTTCACAGGGGATCTCCCGATCCAAAGGTTGCAAAGATCGGTGGGAGAAGCATCATTCCCCAGGTTTGCACATT CACTCACTTCCCTGGTGGGGGGAGGGGAGGGGGTTTCCTTTGGGTCTGTGTTGCTCCTATGTAGGCCATGCCCTGCCCTGCTTTCCTCTCTCTATCC TCTGTGGGTCGAGCTGATTCCTTAATCAGTCCCAATGCAAGTATCTGGATGTTTCAGATAAAGGTTTTGAAGTACCCACCCCTTTGTTCCTCTCTGA GAGAGCCATGCCCCAThCCTGCTTCTAGTTGGCCATCTTTGAAAATAAAATTAAGAAAACAATTTCATTTACATAGCACATCAAAAAGAGTAAAATAC TTAAGAAAAAATTTAACAAAGAAGTGAAAGACTTGCAGCCTAAAAAQTATAAAGAAATTAAGGAAGACCTAAATAAATGAAAAAAATCCCATGTTCA TGGACCAAAAGACTTTGTTAGAATGGCAATACTCCCTAAATTGATTTACAGATTCAATGAAATTCCTATTAGAATCCCAGCTGGTTTCATTGCAGAA ATTGATAACCTAAAATTCATATGGAAAAGAGAGAGATGCAGATTAGTCAAACAATGTTTAAAAAGACAGATAAAGTTGGAGCAGTCACAACTCCCAA TTTCAAAATTTGCTATAAAGCTACAGTAATCGAGACAGTGTGGTACTGTCATAGGACAGACACAGAGATTGATAAAATAGAATTGATAGTCTAGAAA TAAACCATThCATTTATGATGAATTGATTTCCAACAGAGGTGCTAAGACAGTTCAATGGTGGAAAAAATAGTCTTTTCAACAAATGATGCTGGGAAA ACTAGATATCCATATAAAAAATGAAGCTGGATCCCTACCTCACACCATATGCAACAATTAGCTCAAAATGGATCAGATCTAAATGTTGCAGCTAAAA CTATAAAAGTCTTAAAAGAACATATACGAATAAATCTTTGTATACTTGAATTATGCAATGGTTTCTTAGATATGGCACCAAAGACACAATTGACAAA AGAAAAATAAATCAATTGAACCTCCACATTTAAAACTTTGCGCTTCTTTTGCCAGAGATTCAGGTTTTAAAAAACAAAAAGCCTTTGTGCTTCAAAG GACGCTATCAAGAAAGTGAAAAGATGATCCATAGTAAGGGAGAAAATATTTACAGATATGTATCAGATAAGGGATTGTAACCAGAATATATAAAGAA GTCTTACAACTCAATAATAAAAAATAAATAACCCAATTTTTTAAATGGGCAAAGGATTTGAATAGAAATTTCTCAAAAAATAATACAAATGGTCAAT AAGAGCATCAAAAGATGCTCAGCATAGGTAGTCATTAGGAAAACGCATATCAAAACTACAAAGAGGCCGGGCATGGTGGCTCATGCCTGCAATCCCA GCACTTTGGGAGGCCGAGGCTGGCAGATCACCTTAGGTTAGGAGTTTGAGACCAGCTTGGCCAACATGGTGAAACCCCGTTTCTACTAAAAATACAA AAATTAGCCAGGCATGGTGGCACGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGTGGAGACTGCAGTA AGCCAAGATCGTGCCACTGCACTCCAGCCTGTGCAACAGAGTAAGACTCCATCTCCAAAAAAAAAAAGAAAAAAAAAGAAAAAACACAATGAGATAC CACTTTACAGCCACTAGGATGGCTAGAATCAAAAGAATGGACAATAGTAAGTTTTGTTGACAATGTGGAACCCTCACGCATTGTTGATGGGAACAAA ATGGTGTAGTCACTTTGGAAAACAGTTTGATAGTTCGTCAAAATGTTAAATATATAATTACCATATGACTCAACAATTTCACTTCTAGGTATATACC CAAGAGAAATAAAGCATATGTCCACACAAACACTTGCACATAAATATTTATAGCAGCATCATTCATAATAGCTAAAAGGGAAAACAGCCCAAACTTC CAACTGATGACAGACAAACAAAATGTGGCATATCCATACAATGGAATGTTATTCAGCCAThAAAAGGAATGGGGAATGGATCCATACCACCACATAG GTAACCTTGAAAACACTAACTGAAAGAAGCCAGATGTGAAGGTCACATATTGATACTTCTATTTATGTGAAATGTTCAGAATAGGAAAATCTATAGA GCCAGAAGTTAGA1TTGTGGTTGCCAGGGGCTTTCGATGACAGGAGGGGAGGGGAGCAGTCATTGCTAGTGATThCAGGGTTCTTGAGAGGGAGTGA GAAAAAATGTTCTAAAATGTATTGTGGTGATGGTTGCATAACTCTGTGAACATACAAAAACCATTGAATTCTATACTTTAAAAAGGTAAATTTTATG GGATGTGGATTATAGCTCAAThAAGCTGTCATTAAGAAAGGAAAAGGAAGGGAGGGGATAAGAGGGAAAGGGGAGGGAGGGGAGGGGAGGGGAAGGG GGGAGAAAAAGATACATCGTGGCATATCTTCTTCCCTTTTACCTGTCATTATGTGTCAGTGCCTCCCATTGGCCTAAACTACCCAGAAGCCAGAGGG AAAGCCATTTGGGACTATATTCCACTGTGACACTGAGCAGAGCAAGGGAAGGATGGGGACACTTCTCTCACACATCTCTGACTCCCCAACATCTAAC AATGTAAATGACCTAATGATTCAGGATCCTATGACCAGCGACTGTCACCCTCTGTCACCTTTCTTCTGCCCCTTTATCTCTGAAGGCATTGAAGGGG CCCTGCATGAGTCAGGGAGGGTTGGGGGGAGGAGCAAGGGTGGGAGGGGCAGGGAAGAGGGTGGCTTCTCCGACAACTTAAAAGGGGCTTGAACCAC TTCCTCCCCAGAAGGGGTAGTGCGAGGCCGGGCACAGCCTTCCTGTGTGGTTTTACCGCCCAGAGAGCGTCATGGACCTGGGTGAGTGAGCCTTCTT CATGTGAGAAGGAACAGTACCAGGGTCTTGGACACCCAGACTGACCCTGTGGAATGGGGGTGGAGGATGCGGGTGGAGCGCATAGGGGTGCTTCCTG GAGAAATCAGTTCTGATTTGGTGGGCATTGGAAGCTACTTCCAGAGAATGCCCCCTGCTGTCCCAGGAGGCGTGCACCTGCCCTTTCAGACCTGGAG AAGGGGTCAGCCTTTGGTGCCAGTGGGGACAAGGGAGGGGCCGAGATCATGTCTTTCTAAAACAGCAGGGACATAAGAGAGTGGCGGGGCTGGGCTT GGTGGTCTGGCAGAACCTGTTCTCATCATGAGGGTGATAGGTTAGGCCCTCTGGGACCTCTGGGGACAGGTTTCAACAGAGAAATTCTCCCTAGAGA GCTTAGGACCTTTTACCCACTCTCTGATTCCCACCTTTCTCCCCTGCCAAATATTCATATACCTGTCCACTTGGGGTCATGAGGAGATGCAAATGAA ACGTGACTGGGTTGTGAGAATGTGCGTGCATTGCAATGCAAGCTCTGGTTGCTTTCTCTCTGCTGCACATCCCACCTGCTTTGATCTTTTGGCTTTG CTGTTGCCTCTTGCAAGTTAAGGAACGGGCAGGCAACATGGAATGGGATGGCAAGGGGCACTCAGCTTGGAGTAATCATAGCCAGGCCTTCAGCACA GCCCCTGCCCCTTAGCAAACCTCACGCACTCTGCCCCGGCAGATAACTCTACTCTTTAGAAAGCCCTTTCTCAGGTCTAACCTAGAAGGGGTCAAGG GGAAGCACTGAGGGTGTTCTGAGTGGTTCATCCAGCTCCAGACGCCCCCTTTATAAATCTCAGCTGTGGAGTCAGACCAGGCTTGAGGCTAAGTGAC CAGGTTCCTAGATGGCTTGTCTCACCAGCAAACAATGCACCACGGCGGCCTCAAAGCCGCAAAGGGTTGGCTTTAAAAAGTGAAGGTTCCCTGGTGC TGTCCTCACACCCCTCCTCGCCACACCACAGCCTCCTTGATTTCATCTCTTACTTTCCCGCCTGCCCTGAACGCTGGATCTGGACCCAGCAAACAGC TGTGAAAGGGTTAAAGTGGTCACCCCCACCACTGACTGTGAACTCCTGAAAGGCAGGTTCAGGTGCTTTGAGGATGTGAGGAGAAAATGTCTGCGGA ATGAATGAATACACCGTATCAAGAACTCCGTAGAGTTTAGTTTTTGAAAATCTCTTCCAAATGCCTCATTTCCCAGCCAATCTACCCTTAAATCCCA CTCCCCTGCACCCCCTCCACCACCCCCCATCACAATCCCACAGTACAGACGTCACCCACAGAAGACCCTGCTCCAGCCTTTCATACTGGCCTCCAGG AAGGAAACCAAGCAGTGCCCAGTGGTGTGCTACTGGGCATTTGAAAAGCAGCTCCCCGGGGTGGAGCACTGGTAGCTGACTCCAGGGTGGAGGGAAA GTCCTGAATTTGTAGTGCTTGCCAATTTCCATGGTGTAAATTCTCCCACCCTGGCTGATTGATTTCAAGCCATCTACATGACTGAACAGGGGGTTGG GAAGATGTGCAGAGTGTCTTACCCCAGACTAGGTTTAGGGGTGCTAGACTCCTAGGCTTTGATGCAGGGGGAGAGGGTAATCTCTGGTCCAGGAAGA AGGGATATTCTTGCCACTTCACTCAACTTGAGAGAGCCCCAACGGTCAAACCCGAAATACTGGTAGGAGGGGAAGCCGCTGACAAGCTTTACTCAAA ACGGGCTCTCTGGGCCGTTGATGGGGTGGGTGGGCCTTGGAGGATCTGTTGTTCTGCTCTTCATCTGCCCAGCAAGGAGCAAGAGGTGGGTGAGGAG GGAGGGTTTCTGTTACACAAAATGAAACTCCCAAGCAGGGCTGAGCTGGCCTTTTTCACGGTTTGTTGAGCAGCTTGAGGTCACCCTCCCCAACCTT TCGAGCAATGAGACCGAAGATCTTTCATAATTCTCAAAAGCAAAGCAAGGAAAAATGAACCCATGTAGAGATGTGTGCCTCACAGCTCGGACATAAA TGGTGGCAAAGGGGGATGCTGAAGCTAATTCAGGGGCCAGTTTCTTGCCTGCCAGAAACTTGGCTGGGGAGGAGAGGAACGCTGCAGCCTGGGTCGC TGTTTGGAAAAATCTCTCCTCTTTGCTTCGGACATTCAGGCAACTCTCATTGTTGAGGGATTCAGGGGGTGACCAGTCTGGTGGGGAGAGTGACACA TATGTCACAAAGCCACTGCAACAGAATAAGATACAGCATTGACCAGGGCAAGGGCAAGACAAGAAGGGAATAGTGAACCTGGGTCAGAGAGGTATTT AAGGTGGGTTTTCAAGGGTGTGTAGGAGTTGTCAAGCCCAACAAGGAGCTGCAATGGGCCCAGGGATGTGGCAGGAATGGCAACTCCATTGCCATCA GAAGGCCGACAAGGTAATAGAGGGAATGGGCATAAGGTGCAGGAAGTGGAGGGGAGTAGAGTGACCCAGAGGTGCATGCCCCACCTAAAGGCATTCA AATCTATTATTTCAAAAACTCCATGCTGACAAGCAGAGTGTCCTGGGGACTAAGGCTGCAGCCGTGTAGATGGTCAGCTGAGACAACAGTAACAGAG ACAAGAAAGAAGCAAGCGGAGGGGAGGGTGGAGTAGCTGGCCATGCCAAGGAGGAAGATGAGGAGGAAGGACGCAGGCACAGGAGACCCAATCCTTA AAACGTGGTACGGCATCCCTAAGGAATTTGAACTTTATCCTGAAAACAATGGGGACCCATCAAAGATTTTTATTTTTCAAGTAGGTGAATTAAAGGA TGAGATTTGTGTTTTGGAAGGAGTTCTGTGGCAGCAAAGAGGCAGCAAAGCCCGTGTCAGAACAGAGGTGGGGCCGGCTCTTTTGGGGGCCGGGATG TTGGGGGATGGAAGCAGGAAGCACTGGTGGCCAGTGGGGCATGGGGAGCAAAGATTCCCCTCATGCTCCGTGGAGCGTCCTAGATGCAGCAGGCTCA TCAGAAACACAGCCTGATGCAGTAGCCAGAGCCCAAACCTTGCTATCCTGTTCAAATCTCAGGTCCCTCTCTTAGCAGCTGTGTGGCCCCAGGCATT TGGTTAATCTCTCTGGGCCTCTATTTTCTGGAATCTAAGATGAGGATCACCAGGGTAGCTCATGAGATGTTATGAGGGAGAGACACATACAGACCCC AGTGGCCGCACAGAAGGATGGTTAGGAGTGTGGTTGCTGGAGTTGGAGGGTTTCAAAGCCTGCTCCCCTGCTGGCCATTGTGTGACTCTGAGAAAGT TACTTGCTGTGTTTCAGTTTCTCATTGGTAAATGGGGATAATAGTAGCGCCTACCTCATGGGGCTTTTGAGAGGATGAAATGAGACCATACATGCAG ACAGTGTGGCACGCAGTGAGAGCTCAGTGAATATGAATTATCTCATTGGATACAGCAGTTGATAACATAGAAAATGCAAGGTCTACCAGGCTCTCAC CCATCCCTGCCTACTGTCTGAAAGTGGATTCCCCAGATCTCTAGACCTCTCACCACCTCCCTGCTTCTCCTCTGCCTCCCTTATCCAAAAAAAAAGA GAGAGAGAGAAAAGTTGTGTTGGCAGGTGAGGAAGTTCAAAGAGGAAAAAGCTTGGGGTCGCTCTTGGGGCGAQCTGATTGGGCAACTGTGATTTCC TGGGCAGTCTGGAGGACCTGGAAAAATGTGGGGATGGAAGTTCATGGTTTGGAGATGGGGGCAGCCAGCCAATAATTTTCTTTCCTGGATGGGCAGT CTCTCATGTTGGGGGCTCCGGTTGGAGTTCTAGGGAATTTTCATGATGATCATTACTGAAAACTCAAGAACTCAGAAAACACCCAACTTCTAGGTCA ACCACTCCTTAGCCCCAGAGATTCCCAACTTCATTGGTCTCACTGAAGCTGCTGCCCAAGACCAGTTTCTTTATGACTITGTAACAGACAGGGATGA TCTGACTCAAGGCCACTGACCAGGCTCCCTTTTGCCACATACAAGAGTTCCCCTAAGTTTCCCTGTGATGTTTCTTGAAAGCCACCTGTTTTGGACC TACAAGACCCTTGCTCATCCACCTCCTCCAAAACACCTGGAATGAGAAATCACAGGCACACACGCCAGCACTCCCCCAACTCCCCTCCCCTGACGGG AACAGCAGGAGTGGGACAGCGTCCGGGAGAAGGGGTTATCAACAGAGTTCAACAGAAACACAGTTCTTGCTCCTCAGATCTCACCCGTTGTGACTTA TCAAAACTTTGAGGTTTCTCATTTCTCCCTGACAGTCAGAGCGGGCTTTCTCTAGAGTAACCGAAAGACACTTACGTGTTTTAAAGAAACCTCGAGA CTCGACCTCTAGATGAGTCAGTGGAGGGCGGGTGGAGCGTTGAACCGTGAAGAGTGTGGTTGGGCGTAAACGTGGACTTAAACTCAGGACCTAAGGG GTAATTCAGTGAAAAAGGGGAATGAGCGGTGGGGAGCTCTGTTGCAACAGGGTCCAATCGCAGCAGGACTACAAATGCCCGAGCGCAGGCTGGGAAC GAGGGGACAGCGGCTGCCTGTCCCCAGAATAGAAAATGCAGCTAGGAAGCCCTCTTTGAGTGGACAGCGGAGGACTGGACTGCCAGGCCAAGCATCA GGGGCTTCATCCTCAGGGCCGGTTAGAGCCCCTGAGGATTTAGGAGGAAGGTGAGGTGGGGACTGCCATCAGAGCTAAGCTTTAGGCAGATGTGTCT AGCAGTAGTGTGCAGGACTATTTGCTCAAGGCGGGAGAAATACCTATTTATTTATGTAGCCCGATGCAGTCTCTCCTTCCCGGAGGAACTCCCAAGC CCAGAATCCCTGGCTTTACACAATTTCCGGGGAACACATTAACCAACTGCAACCTGGGTGCCATGCAGGGAGGCTTCCAGCAGGTGGTGCTGTGGCC AAGGACACGGAAGCGCTGGGCTCTCACTGCTTCCCCAGCCTCCAGGAGAAGGTGCCTTAAACAGGTTCCCACGCATTTCCTGGCGCTATTGAGCTTG GAGCTGCCAAGGGCCTGCCTTCACTTGTGGCATCGCAGTTACTGACTCTCCAGTGGGCCAGGCCCTACCTAGCTGGGACCTGAGGGTCAGGATACGG GAAGAGGGCTACTGCCGCCCTGACTTGTAGGTAAGCTAAAACATCTAGGCAAATTACTCTGTCAACTGTCCTCCCTGCTCAGCCTCAGGAAGAAATA AGTTCCTGCTGGGCCCCAGGCTCAGCCACAAAACCAGACTGAGCACATCTGGGCCTTGTGCTACACCGGGGTCCCCATCAGCTGCTCAGACCCCAGG AAGCCTCCTGACTTCCAGAACACGTCGCTTCCCAAAGCTGACCCTGTTCCCCCTTTCACCTGCCCCCCAAGCCTAAGTTAGAAAACAAGTTAAAGGA GAGAAAGTGTGTGCAGGCACTTCAGTTAAGCAAAAAAATAAAGAAGTCGTGATATCAGGAAAGAGCGTCCTTCCCCCACACTGCAACAGGACAGCAT CCCTTCTGTGTCCTCTCGGGCCATCTTGATGCCCTCTCCCTTGGAAAAAGGACAGGCATTCGTTTACTTGTCATTCATGTATTTATTCATCATTCAT GTATTTATCATTCATATATTCATCAGCACACAATTGTGGGCCACCTCCTCAATTCTGGGCCTGCACAAGATAAAAGGGAAGGGATCTCTGTCCCAAA GGCAGGCCAAGGGTGTGCGCCCAGTGGACCAACAGTCAGTGCTGAATGAATGTCATTTCAGTGAGGGGGTGTTGTGGAGCTGGTGGAGCCCTGAGGC AGTCTCCATCGCTGTGGACCAGTAAGGAACCTCATCCCTCTACCCAGCCTGTGAGGTCATCCTCCTTCCTCAGCCCACCTCCCTCAGGAGACACTCT GGCTTGGCTTCATGCACGTGTGGCTGCGCACTCACCTGGATGCCAGGAAAATGCTCCTGGGCCAGTGGCTACCAGCACCAAAGCAGGGCTGGAAACG TGTGCACCTACCCCACGACCTCATAGCTTTGCCGCCTCATCCCACATCAGGTGGAGTGGGAGGGGGCACTCAGACCCACCAACCAAGCTCAGTCTTG AGGGGTGGTCTGGGCTAGAGAAGACTTCCCAGCTCCAAGAAGCAGCCCAGATGGGCCAAGACAGGGGGTGGGAGGGGCTGCCCTGCATTCTGATGCT GCTTCTTTCCAGGACCTGGGAGTGGAGGAGGACAAGAAGGAGGTGAGGACAGTGATGCCGGGCAGCAGGCCAGGTGTTCAAAGGCACAATCTGGTTC TGATGTTCTCTTTCAGCAAACACAGTGCCTGGAGCTTGGGAGGAAAGTTCCCAACAGCGTCTCCCCCTCCACTGCTTTCTTTAATAACAAAGACTTG TCCCTGCCAAGCAATAACTTTCTCGCCTTGTCTCCTACAGGGAAACCAATGAAAAGCGTGCTGGTGGTGGCTCTCCTTGTCATTTTCCAGGTGAGGT TCTCTGCCAAGGAAAGCTCTGTTCCCTTCTCCACACGGCCTCCCAAGTCAGGGGTTTAGTGGAGGAGCTGGGCATTTGCTAGAAGATACAAGACCCA GACATAAGCCCGCCTGCCACTCATTAAGCTAATGGCTGCCCCCTCACCATCTGCTGAGTGACCCTGGAGAGCCACAGATGTTCTCTGGACTTCCTTT ACTCCATTTAGGTTAAAACATGGGGGAAAATAACTTACCACCTTCCCTATCCCACCTCCAATCTCCCTGCCCAGGAGACAGAAATATGGACTCTGAG TTCTTAGAGAGAGAAGAGCTGCAAAGCA1TATGTTACTGGGTTTTGTGCACGTGTGCTGAGAAAATCACCCTGGATCTGGCGATCTTGTTACT ATCCTATCGCCCCAAAGTTGTCTCTTTCCAACCTTCACCCAAAGGCTTCCCTCGCAGCCCCCGTTTTCTTTGGTGAAATAGAGACCCATCCGGCCTC CCTGGCAGGGGAGGGAAGAGAGGATGGGGCCCTAGGGATGGGGAGAGGGGTGGATGAGCACACACTTTATAGCAGGCCTGAACTCGGCAGGAACAAA GACCCTCACTTTACAAAGTTCTGTTTCTCCATCCAGAAACAGACAGAAAGTGTGCCTCACCAAGTGCCAAAGTTAGAAGAAACTGTAACTCGCAGAG TCAACTTTCTCCCATTTGTTAGAGGTGGGAGCTCAGAGTAGGGGTAGGGGAGTCCAACTGAGGCCAGAGCTAGAGAGGCAGTGCTTCAGAATTCGGC TCATCCCCAGGTCTGGAGGCCAGAGGGGCAGCTTTCCAGAAGCTCAGGCCAGAGGCAGGCCCCAAGCTGGGCACTGTTCCCAAAACCCCATCCCAGA GGCCCCCCGGAGCCTGGGCTGCAGCCCATAGCCTGGCCCCCTTCCCCATCACCACTCCCTCCTCTCTCTCCCCTGTCTCCAGGACTCTGGGGGGCTG TATTGCTGGCAGTGGAGGCTGGAAGGGTGGGAAGGGGAGGAGGACAGCTGAGGCTCATTCTTCCCTTTCACTTGGGGAGGGGGTGCTCAGATAGGGC AGGATGTGGTGGGGCTGTGGGCTGCAGAGGCAGTGAGGCTAGGGGAGGGAGAATTATAAAACAGGAACAAGGTTCAAGGGGAGAAGGGAAGGCAGGA CCGGATGATGCAGAGTGCACTTCATAGAGGCCGGGAGTACTGCCCTCCAGGAAGGCTGAGACCCCCTCATGTCCAGGGACCCCGGGTCTAAGGCCTT GGGCCGTAACCATGGCTGGGCCAAAGGCAGCAGCCTCCTTCAGGGCTCCCAGGCTGCAGCCATGCCCAGGAAAGGGAACAGGGGTTGCTCTGACTT TTCGTCTCAGGCTAGCAATGGCCAAAGAAAAGGCTCCTGGACATCATTTTGTCCTCACCATGTTCCCAAGCAGGACAGTGATGAATCCAGAACTTGG GTGTGAAAAAGAGATAGAGACAAGATGCGGTGAATCCCTCCAGCATAAATGGATAGATCCCACCGTCCCTGAGCTGTGAATCTGGTTCCTGGTGA TAGAACCATGAGCCTCGTGAGGCAGGTCCTCCAGCCCAGCTCCCTGCCCTGCACAAACCCGTCCATCGCTGTGCGCAGAGGCAGGGGCAGGCATGGA CCCCCTCCTTCATTGATAAATCACAGCAGGCTGCTGAACCTTCACCCGACCCTGCAGACGGCTAAAAAAAAGCTCCAGCAGCTGAGTCCTGCTGATT GGGATCTGCCGGAAGAGATGCGAGGAAGAGAGAGGCAGAGAGGTGGGGGGAGAGGGCGGGAGCACAGAGGGAGAGTGGGAGATGAGAGCTGCGCTTC CTTCCAGGGACACAGCTGCTGAGGAGTCCTCGCCCCCACCCCCATGGCCCATCATCCATTCACGGAGTTTATGGCACTTGGGCTCACGTTGCCTGAG CTCCTGCTGGGTGCTAAGAGGGGACCCGGATCTAGAGTCTCTCCAGGTCACCCACCACCCATGATCACAGCAGTTTGCCCCAAAACCCAAGGCTTCA TGGCCTCAAAATGGGAGCATTTGCCTTCCTCTCTTACTCCAGGCCCTCCTCAACCTTGACCCCCAGGTGGATTTTTTCCCCCCTAAAGCTGAGGTCT TTTGTAAGCCCCCTGGAAAACTCCACCAAGTTCTAAAGGAGGGTCAAGAAGAAAGACACATGTTCCCTCTCTCACGGAGCTTCCAGGGGGCAAAATT AAAGCTCCATGGAGAGGAAATGGTGCTGGAGCCTGGGCTAGGTACCTCACAGCAACCATGGGAAGCAAATAGGATTCATCTCCATTTCACAGAAGAG AAAACTGAGGCTCTGAGAGAGAGAGAGAGAGACAGAAAGAGTTTAACCAGCTCAAGGCTCATCTGGCCCCAGAGCCCAGCTGATTTCCAGTCCCCTG TCAGCACATGTAGAGTCTCTCAGACTTGGCAAAATCAGCCACTTGCTACTTACTAGCAGAACTGTAGAATCTCAGGCCCCACCTTAGCCTACTGATT CAGGATAGACATGTTCACAGGATTAATCAGGTGATGCGTAQTTGGAGTTAAAATTTGAGAAGCACTGATTTAAAACCAAGAATCACCTGGAGACTTT AGGAAAACACAGATTCCTAGACCCATCACTTGAGATTCTGGTTCAGAATTCTCAGGTGGGGCCTGAGAATTTGCATTCCTAACAAGTTCCCAGGTGA TGCTATGATACTGATGATGCGGACCTCACGATGAAACCACTATTCCTCCCGCCTGGGCAACATGGCAGAATCCCATCTCTACTAAAAATACAAAAAT TCGCTGGGTGTGGTGGTGGCATAAGGCTGTGGTCCCAGCTACTCAGGAGGCTTGTGGTGGATCACCTGAGCCTGGAGAGGCCGAGGCTGCAGGGAGC CATGATTGCACCACTGCACTCCAGCCTGGGCAACAGAGTGAGACCATGTCTCAAGAAAAAAAAAAAAGAAAGAAACCACTGCTCTAGGCTAAATCCC AGCCAGAGTTGGAGCCACCCAGCTAAACTGGCCTGTTTTCCCTCATTTCCTTCCCCGAAGGTATGCCTGTGTCAAGATGAGGTCACGGACGATTACA TCGGAGACAACACCACAGTGGACTACACTTTGTTCGAGTCTTTGTGCTCCAAGAAGGACGTGCGGAACTTTAAAGCCTGGTTCCTCCCTATCATGTA CTCCATCATTTGTTTCGTGGGCCTACTGGGCAATGGGCTGGTCGTGTTGACCTATATCTATTTCAAGAGGCTCAAGACCATGACCGATACCTACCTG CTCAACCTGGCGGTGGCAGACATCCTCTTCCTCCTGACCCTTCCCTTCTGGGCCTACAGCGCGGCCAAGTCCTGGGTCTTCGGTGTCCACTTTTGCA AGCTCATCTTTGCCATCTACAAGATGAGCTTCTTCAGTGGCATGCTCCTACTTCTTTGCATCAGCATTGACCGCTACGTGGCCATCGTCCAGGCTGT CTCAGCTCACCGCCACCGTGCCCGCGTCCTTCTCATCAGCAAGCTGTCCTGTGTGGGCATCTGGATACTAGCCACAGTGCTCTCCATCCCAGAGCTC CTGTACAGTGACCTCCAGAGGAGCAGCAGTGAGCAAGCGATGCGATGCTCTCTCATCACAGAGCATGTGGAGGCCTTTATCACCATCCAGGTGGCCC AGATGGTGATCGGCTTTCTGGTCCCCCTGCTGGCCATGAGCTTCTGTTACCTTGTCATCATCCGCACCCTGCTCCAGGCACGCAACTTTGAGCGCAA CAAGGCCATCAAGGTGATCATCGCTGTGGTCGTGGTCTTCATAGTCTTCCAGCTGCCCTACAATGGGGTGGTCCTGGCCCAGACGGTGGCCAACTTC AACATCACCAGTAGCACCTGTGAGCTCAGTAAGCAACTCAACATCGCCTACGACGTCACCTACAGCCTGGCCTGCGTCCGCTGCTGCGTCAACCCTT TCTTGTACGCCTTCATCGGCGTCAGTTCCGCAACGATCTCTTTCAAGCTCTTCAAGGACCTGGGCTGCCTCAGCCAGGAGCAGCTCCGGCAGTGGTC TTCCTGTCGGCACATCCGGCGCTCCTCCATGAGTGTGGAGGCCGAGACCACCACCACCTTCTCCCCATAGGCGACTCTTCTGCCTGGACTAGAGGGA CCTCTCCCAGGGTCCCTGGGGTGGGGATAGGGAGCAGATGCAATGACTCAGGACATCCCCCCGCCAAAAGCTGCTCAGGGAAAAGCAGCTCTCCCCT CAGAGTGCAAGCCCCTGCTCCAGAAGATAGCTTCACCCCAATCCCAGCTACCTCAACCAATGCCAAAAAAAGACAGGGCTGATAAGCTAACACCAGA CAGACAACACTGGGAAACAGAGGCTATTGTCCCCTAAACCAAAAACTGAAAGTGAAAGTCCAGAAACTGTTCCCACCTGCTGGAGTGAAGGGGCCAA GGAGGGTGAGTGCAAGGGGCGTGGGAGTGGCCTGAAGAGTCCTCTGAATGAACCTTCTGGCCTCCCACAGACTCAAATGCTCAGACCAGCTCTTCCG AAAACCAGGCCTTATCTCCAAGACCAGAGATAGTGGGGAGACTTCTTGGCTTGGTGAGGAAAAGCGGACATCAGCTGGTCAAACAAACTCTCTGAAC CCCTCCCTCCATCGTTTTCTTCACTGTCCTCCAAGCCAGCGGGAATGGCAGCTGCCACGCCGCCCTAAAAGCACACTCATCCCCTCACTTGCCGCGT CGCCCTCCCAGGCTCTCAACAGGGGAGAGTGTGGTGTTTCCTGCAGGCCAGGCCAGCTGCCTCCGCGTGATCAAAGCCACACTCTGGGCTCCAGAGT GGGGATGACATGCACTCAGCTCTTGGCTCCACTGGGATGGGAGGAGAGGACAAGGGAAATGTCAGGGGCGGGGAGGGTGACAGTGGCCGCCCAAGGC CCACGAGCTTGTTCTTTGTTCTTTGTCACAGGGACTGAAAACCTCTCCTCATGTTCTGCTTTCGATTCGTTAAGAGAGCAACATTTTACCCACACAC AGATAAAGTTTTCCCTTGAGGAAACAACAGCTTTAAAAGAAAAAGAAAAAAAAAGTCTTTGGTAAATGGCAAATGAGCGTGTCTTTGTTTTGCAATC CCCCACACCCQACCTGACCGTCCCCTCTCCCCTCCTCCCTGCCCTCTCCCAGGCCTCGTTTCTTAGAGACGCTCAGAACCACAAAGTTGCTCAGGAA TGCTCTGAGCCCGTCTGGTGACACAGGACCAAGAGGCTGAAAGGTAGAAGGAAGATGATGACAGGAGGTCCATCTTGCAAATACCCTTCCAGAGTTC AAGGGATAGGCCCCAAGCCTGCACAGTCAGCACTGAACCGGACATGCTGATCCTACTGCAGCTTTGGGAAGGCCAACTTTTCCGGGTAACCTCGATA CCTGGGGACTCTGCATTTAGCAGCTCTTGCACAGTAGCCTGCTCACCTGTCCCAGCTCAGACCAGAACTAGAGCCCTTAACCTTTTGTCAGCCCCTT AGACTCTGAAAGCTGGGGTTTGGAGGGAGGGCCTTTCTGTGGGCTTGGAGACCACAGCATACTGGACTAGGGGTCAGGGATGAGACCCTTTGCTGGC ATGAGAGCTGGAACCACCCATGATCCTCTCTGCTAGCCACTGTAGCAGCAGTGGCCTCCGTGGTGTATGTCATAGTCCCTTCCTGCTGGTACAACAA AATGCCACCGATGTAGTAATTTACAAACCATAGAAATGTATTTCTCACAGTTTTAGAGGATTGGAAGTCCAAGATCAAGACGCCAACAGATTCAGTG TCTGGTGTGGACTCTCTCTGCTTCCGAGATGGGGCCTTGCCATGCCCTCTGGAGGGGACAAACACTGTGTCCTCATGTGGTAGAAGAGTGGAAGATC ACAATGAGCCTAACTAGTTCCCTCCTGCTCTTTTATTGCTATAAGGGCATTAATCCCGTTCACAAGGGTGGATCCTTCATGACCTAATCAACTCCCA AAGGCCCCCCCCAACTTCTCATACCATTGCCTTGGGGTTTATGTTCCAACCATATGAATGTCGGAAAGATACATACATTCAAACCATAGTGTGGATA CTGACTGTGGAGGAGCAGGGAGAGAGGGACAGACAAAGGCCCCCACACAGGCCAGGTGTCCGTGTCATTTCGTGCCTTGGTGCCACCCAGAGCCGTG ATTCTGCAAGCCAGAGAGCAGGTCAGTCCAACCTACAATTGCGTCAAGAGGGGTCTGAAGGACCCAGAGCTGCAATAGCTCTGGGCCGTGGGGAGCT AGAGGGAGGGCTGAGGCACTCACGCAATAGGTGATTCCATCCATTTCTCCAAGTGGAAAGAGCCTCGTTGAAAATGGAGCTGCCTGGTAATGACACC CATTCGCTCATCTCGCAAGCACGTGACATTACCCTCCTCCGAGAGATGCACTGGGCTGGAAGGTTTTTAACAAGATTTGTCAGCTGGTCTCCAAGCC GGGAATTGGCGCCCTGAGAGGAATGAGCCTGGCACGGATGCAGTCAGCGTGGAGCGGCGTTTGCAGCAATGGCATTATTATTAAATTGGCACAGCTG CGACTGTGTGCGTGAGCGTGTGGCCAGGGGGCAATGCCAGTGTGCGTGTGTGTCCCCGAGGGGAACCTGCCGGAGCGCATGTGCGTGTGGAGCCCGC TGGTGTGGACATCCTAATGAGGTTACAGATGGGAAAACAACCCTCGGTTCCTGAAGGGGAAGAATGTAACAGAGCAGTCATGCAAAAGGCAGCCAGG CCAGCCGCACAAATGCGCCCCCTTCAGCTGCAGATACATTTTTCTAGAATAACTGGACATCTCCAAATTTTACAGAGAAAACAAAACCCCCAGCAAT TTGAGCTTGGGGTGACCCCTGGGAAGAAGGAAAAGGCCCCCTGGGAGGCCCACCCAGGGCTTCTCTCTTCTTTTCTTACCTGCTTCATACATCTGAA CCCTCTTCCCAGGTTCACAGCCAATAAGCCTTCTCCAGTCACCTGAAATTTCCTTTTCATTTCATCCCCAGGCCCTCATCTCCCTCATCCTTGCTGG CTGCAACCCCAAGCCAAGCCCAAGGTATTCCCAGGCCACAGGTCTTCCCTTTCAGCTAGAAGCACCACACCTTTCTCATCACAQACTCACAGAGCTC CAAGGGACCTCAAAGATCAGCTGGGCCAATCCCCCAGTCATTTTCTAGATGGTGAAACTGAGGCCCAGCGGGGAGAAGCTGACTTGCCTGAAGAGGC GTGGCAATGCAGGGATATTGGTTAAACTTGCTTTGGAAGCCTGAGCGTCTGGCAGGGTTGCAGGAGGGTGTGGGGGAGAGCAGAGACTCTGGAGCTC TGCCGACTTTAAATCTCATCTCTACTGCTTCCCAGCTATGTGACCTTCAGCTGTTGCCCAACTGGTCTGAGTCTTGGGTTTCTCAACTGCAAAATGG AGAGGATTTGTGTAAACAGTTAGCACAGTGCCTGGAATGTTGAGTGTGGTGGTGAGGAAGAGGGACTTTGCAGCCAGACTGCCTGGTTTGAACCCCG GCTCCACTGCCTGGGCTGGTTACTTAGCCTCCCTGTACCTCAGTTTCTTAATCTGTATAATGGGGATACTAATGGTACCTATGTCCTAGGATTGTTG TGGAAGGCACGAATCCATATATGTAAATGCTTAGAAAAACTTACATATGTGTTGTTGGTAATCTTTAGGAGATGTTTAAGAAACGGTAACTCTTAAA AAAAAAAGTTGCTAACCACAAGGAAACCAAATTCAATTCCTTAGCCCATTTCCATCCCCACAGAATTTATAATTCAAGCTGGAAGGCAATTTAGAGA TGAGTGAATCTGGCCTTTCCATCCATTGCATGGTGAGTCAACTCGTGCTCTGAGAGGGAAGCAACTAGCCTGAGGTCTCTTGGGAGGTCTTTTGCTT GCTGGAACTTTAACCTAGTTCCCTGGGCTCCTAACCAGAGCTCTTCCCACCAGACCCTGCTGGGCTCACGGGAACATCCCTGCACATCCACCGTGGC ACCCGCCCTCATCCCACGCTGTCTCGTTCTCTCCGGCAGGCACCGTTCATCTTGTCCTTTGATTAGGTCCTTAAGGAGAACCTCCCTTCTCCCCTTT AAATAGTTCCTGTCCTTATCACTGAGTCTGGAGAATGAATGAAATATAAAAGAAATATGGCAGCGGTCCCAAAGGAAATCAGGCAACTGATCTTTTT AAGAAAGGAAGATGGGCCGTCTTCTCTGGGAATGGTTCTCAGTTACATGTCTTTGTTGAGGGTGAACAGTTGGAGGAAAAGAAACAGACCTAAAGGG ATTGTGGGGGAATTAAGGCAAAGGAGATGGGGAAAGGCAGGGGGAAGATGGGGCAGGAATGGGTTTAGGGAATATACACTGGGGGGGGCGGGACTTG AAGCAAATCTTCAGTGGGTAGTTAGATGTCCCATCCTGCATGCACACACATGCATGTGCACACACACACACACACACATCACATCACACACACACAC ACATAGAGCCTCCCCAGGTCTCCCAATCTCAGGTGAGGAGAAGGGGGCTCTATTAGTCTTAGAGACAGGTGGGCCCATGGCCTTCTTTGCAGAGAAG ATGGTTAGAATCGGTCATGTGTCTCTGGTCTGAGACCCTAGAGAAACTCCAAGGAGAATAAAAAAGGTTGGGGGGGGGCCTCTCCCTCAACTCAAAA GAGCAACCCTATCAGGCTTCAGAAAGCAAGCCCTCCTAGCACTCCAACCCACGAAGGAGCAGCTGAGAAAGTCCCCCAACTCCTCCAGCAGCCACCC CCTCTGTTCCTTCACTTCTCTTGGGCCCAGGCAGAGACACAGACAGGAGTCTGTGTGCAGAAAAAAGCTCCCCCAGGCCCTTTTCTGGGAGACTGCT CCAGACTAAGCGAATCTCAGCTGATCTCGTCGAAATCAGAAACGCCAGGATGTGTATTCCCCACGGGCTCCTCTCT5TTGTGTCTGTGCATGACCCA ATTCAGACTCCTCTGCCGCTGTCAGATTCTCTCCTGCCCATATTCACTTTGAGGATGGATATAACCTTATTTTTGTGTGTTGTTCACTAACCCCAGG GACTTCGCTAGCTGGGCTGTCCTACGTGGTACAGTAACCACCACATAGTGTGGCCTCCAGGTTCTCATCTCTGGGTAAATAAACATCTCCGCACAGG CTTGGCCAGCTCTGGACTGGCCTCAGTTCCTGCATGATGCAATAGGTCTCCAGGTCACATATCCGTGCCCACTAGCAAGAGGAAGGTAAGGAGATGG TTCTTGCCCTGAAGTCCTCTTGTTCCTGTGTCAGAGTTTATTTAGGACAGAATAGTTTATATTTGCTCCAAGTAAATAATATCTGACATTGGGAAGC ACAGCAGATGCAGCAGATGAGATGCCCCCAAACCATTTCCCAATGTTTAAAAGAGGCCTGGAAAGGACAAGCTCATTGATCTCATTTGGTTTTATGA AACTGCACTCAAGTGACTGAAGCAGAAACCTGACCACGTGTAAAGACTGAATGGCTCAATCTGCTTCCCAGGCCCAGAGGGTGTTTTCTGTGGCCTG GCCCAAGGCCTATGGTGAAGCCGGTGCTAGGGGTCACCTATGTGGGAGCCAGCTCTGCCTCCTGCCCCGAAGCTCCAGAGACTTCTCCTACAACTGA CTCTCTGGACACGCCCTCTTGCTTGCACTAGTATCTCTTACCTGCCACCTGCCCTCCTCCACACACCCCGATTTCAGGGAAGCTCAGCTGCTGAGAG TGCTATTGACAACCTCTGGACTTGGAAATCAGGAGGAAGGGAATGGGAAGAATGGTGGCAGCTTTGTGCCTGGGCTGTTCAGGAAGACATCCCTCTG CCTTTGTTCTCCAGGGCAAGACACAGGGCTAGACACGCCGGAATCCTTAAATCCTTTGTCAAAAGCAGAACTGGGATTTTCGTCCAAGGACTACACC TGTCCTGTCCTCAGCCTCCTTCTCAGTTGCCCCCCCTCCCACCCGGCTCATCAGAGCCGAACCCTGAGGAAACCATGGACCGAAAGACCTTGTGAGC GGAAAGAGACGTTGAAGAGGTGGAGGGTGTAATGAACCTAGGCGGAGACAGGCTAACATTTACTAAGTGCCCGTGATGCACCAAGGACTAGGCTAGC TATACAACCTTTCATTGAATTCTTATGACAACAGAGAAGGAAACAGGTTTAGAGAGCTCATGTAACTTACCTGTGGTGACACAGCTAGCAACTTTAT TAAGATTTTGTTACGTACTATACACTGTATTAAGCATCAGTATCTTATCTCATTTAATCCCCACAACAACTCTACTAGAGTCTCATTTAATAAATGA GGAAACTTAGCCTCAGAGAGGTTAAGTAACTTTATCAATGTCACACAGCTACTAAGTGATTTCAACCAGTTCTAGCTGCCTCCAAATTTCTTGCTTT AGTCACCQTACTTCACCGTTCAACTAAACAGCTGTTTAATACCAAATATTTCTGGAGCCCCTACTGAGTGCCAGGCACTGTGCTGTGTCCAGCCAAC ATCTTTCAAACCCTGCCAGACACAGAGCTCTTGACCTGGGAGAAGGGAGAATCAAATAACAAAGACACAGCCCCCACCTGCCAGGGGCTGTGACCCC ACAGCTGGGCAATAACCAGGTCTTTGCTGCTCCACAGTACCTTGTCCCTGCTTCTCCCCTCTAGGCCCTGCTTCTTACCTAGGCTTCCTCCATGGGC TAGCCCTGCAGATGACTGAGAGGGCTGAGATGGCTTTGCCACAGACTAGTCACTGGGCAATATGGGCAGGTCACCTCCCTTTTCTGGGCCTCCAGCT GGCCAGTGCTCAGCGGGGTAGGGCTCTGGGCATGTTGATGCTTGCACGAGGTGCAGGGCAAGTGTGTGAGGGGCTGAGGAAGCTGCTCCACCCCCAG CTGTGGTTTCTGGTGGGGCCACCATGGCAGCAGGTGGACGGAAGTGTTTGTCACCCTTCCAACAAAGGCAGTCAAACAAAAGCCTCCCAGGGCACCA TGGGAATAGGCGGCAAGGGCGCCAAAAATAAAACACACTTCTCCTTTGATAGGCATCGGTGGCAGGCATAGGCAGCTGCTAAGGGAGTCTGTCCTTG GGGTGGTGAGGAAAGGGTTCAGATTTCGTGCCCAAGAACACTCACACTCACAAGAGCTGTCCCACCTCACAAACAGCCCACACATACAGATGCTCAA TATTCACACAAGAAACACCACCGCACACATCACACACACACACACCAACACAGCAGTCACACAATCAGCATACACATATACACATACAAATAGAAAA CTTGCCCCCATACAAGACCAGCTTCATGGGCCGCGACCTGCACAGTCACTCTGGGCCCTGCACTAAGGCCCTGCACTAAGGCCCATGCTGGGTATAA TGCTTTGCTGCCTGCACTTTGAAATTCTTAATTATTTTTAAACAAGGGGCGCAGCATTTACATTTTGCAATGGGCCCTACAGGTTCTGCAGTTGCTC CTGTGGGTGTGCACTCATGAGAGCGTTCACTACCTGCTTAAGCATACCTTTTAACACTTTTACACTGTTGATGGGAGTGCAAATTAGTTCAACCATT GTGGAAGACAGTGTGGTGATTCCTCAAGGATCTAGAACCAGAAATACCATTTAACCCAGCAATCTCATTACTGGGTATATACCCAAAGGATTACAAG TCATTCTACTATAAAGACATATCCACACGTATATTTATTGCAGCACTATTTAQAATAGTAAAGACTTGGAACGAACCCAAATGCCCATCAATGATAG ACTGGATAAAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCACAAAAAGGAATGAGATCGTGTCCTTTACAAGGACATGGATGAAGCT GGAAACCATCATTCTCAGCAAAATAACACAGGAACAGAAAACCAAACACCACATGTTCTCACTCATAAGTGGGAGTTGAACAATGAGAACACATGGA CACAGGGAGGGGAACATCACACACTGGGGCCTGTCAGCGGGTAGTAGGGGGCAAGCGAAGGGAGAGCATTAGGACAAATACCTAATGCACGAGGGAC TTAAAACTTAGATGATAGGTTGATAGGThCAGCAAACCACCATGACACATGTATACCTATGTTACAAACCTGCACATTCCGCACATGTATCCTGGAC CTTAAAGTAAATTAAAAAAAAAAAAAATCCTACCTATATAGACAAGAGTGCATCCGCTACACACATACACACAGATGCACAAACACATGCATGCCAC AAATGCAACACCCACACAAACAGCAATAGCCCCCCATGTTCACGCGCCAAAGCACACACATTGATACCCAGAAGGGGTCCAGACGCTCACAAGCAAC GCTACTACATGCAGCCTATGCCCTGCAGCCTGCTGACACAATTCAATTGACTTAACATTGGGGGCAGCAGAACAATGTGAAGGGAAGGGGCTTGGAG AGAAAACAGGTTCATGTCCTCCACCTGCAAACATCTCCCACCTCTCTCTTCGGCCCTGGGCTCACCCACCCCACTCAGCGGCTGGGACCAGAAGAAA GGGAGAGCCAGGGAGGTGGGCGCATGGACGGAAAGGGGACAGGGATGGAGGTGGAGAGGGAGAGAGAGAGGGCAAGAAAGAACGGGTGGGGAGTGGG GGCAGGAACTGAGtCCCCAGGTGAGCTGGCCCCAGCAGTGGTCTCATAAGAGCTCAGAAGGTCTTGGACCCAAAGCAGTAAGAACAATGCCCCTGTG CTCCCCGCAAGCACAGGGCGGTCCCGCCCTCAGAGTCAGTCAGAGGATGCCCACCTCCCTTCTTACTAGCTACACAGCCTTGGGCACGCCGTGTAAC TCCGGGCCTCAGCTTCCTCCTTTGTGGAATGGGATAGCCAATTCTACATTGCAGGGTGGCAAGGCACACACAGACACAACACCTCCTGGATTCCTGC AGCAATCAACAGCTCGTCTCGTGATCAGGCCTGCAATCTGATTCTTGGCACAGGAACTCCAGACCCCCTCATTACAGCAGACATTTGGAACGCGTTT ATTTCCCATCTTCTCCTGGTCTCACTTCACACCTCACAGCCAGGTACAAGCACAGAGGTGGATGTAATTCATGGCCTCATGGCCACCATCACTTCAG GGACCTTCAGGATCCTGCAGCCCCATCCTGCCCCACCCCCTACCCAAACCAAGCAGGACTCCAAGGCCTGGAAATTTTTCTTCCTCCTCTATTCTTT TTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTGGGCAATGGCGCGATCTCGGCTCACCACAACCTCCGCCTCCAG GGTTCATGCCATTAGCCTGGCTCAGCCTCCTGAGTAGCTGGGACTTCAGGCACCCACCACCATGCCCGGCTAATTTTTTGTATTTTAAGTAGAGACA GGGTTTCACCGCGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCAC CGCGCCTGGCCTCCTCCTCTATTCTTTACCCCCAACCTGTATTCTCCACCCCCAACCCTAACCTTCCTGATTTATTTATTTATTTATTTATTTATTT ATTTATTTATTTAGAGACAGAGTCTTGCTCTGTCGCTAAGGCTGGAGTGCACTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGACTCTCCTG CCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCGCCATCACGCCCAGCTAATCTTTGCTTTTTTTTTTTCTTTTTTTTTGACAGAGTCTCGCTC AGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAAGCTCCGCCACCCGGGTTCACGCCATTCTCCTGCCTCAGGCGCCCGAGTAGC TGGGACTACAGGCGCCCGCCAATATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGtTAGCCAGGCTTGTCTCGAACTCCT GACCTCTAGTGATCCGCTCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATCCCTATTTAAAATTGTCCCAGCCTCTGTCCCTTCCCTGAAAAC CCCATCATTCTGTTAGGTGATACCAGATTCTTAAAGAGTGATTCGGGAAAAACGAATGGGCCCTAAGGGGCATGCCAGTGTGCCCCATTCCAATTAC AGTCACCCACAGGAGAGAGGAAAGGTCGTCCAAGTGGCCACCAACAAGAAACTATTTCATCAGATTTCTTTTTTGTTTGTCTGTTTGAGACGGAGTC TCACCCCGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCTCTGCCTCCCGGATTCAAGTGATTCTCTTGCCTCAGCCTCCCA AGTAGCTGGGACTACAGGCACGCAQCACCACATCCAGCTAATTTTTGTATTTTTAGTAGATACAGGGTTTCACCATGTTGCCCAGGCTGCTCTCAAA CTCCTGACCTCATGATCCGCCCACCTAGCCTCCCAAGGTGCTGAGATThCAGGCGTTGAGCCACTGCGCCCGGCCTATTTCTTCAGATTTCTTATAG GACATAAGTCACTCAGATCCCCTCACAGGCTTTCTGTCAACTTACTGAGAGGGAAACTGAGTCAAGGAAGAGTGAAGTGACTTGGGTGAGCAGCAGA GTTGAGGGTTGTGGTCTTTCTGATGTGCAGTCTCCATGAGACCAGATC HUMAN SEQUENCE—mRNA GTGAGACAGGGGTAGTGCGAGGCCGGGCACAGCCTTCCTGTGTGGTTTTACCGCCCAGAGAGCGTCATGGACCTGGGGGTCCAATGAAAAGCGTGC TGGTGGTGCTCTCCTGTCATTTTCCAGGTATGCCTGTGTCAAGATGAGGTCACGGACGATTACATCGGAGACAACACCACACTGGACTTACACTTT GTTCGAGTCTTTGTGCTCCAGAAGGACGTGCGGAACTTTAAAGCCTGGTTCCTCCCTATCATGTACTCCATCATTTGTTTCGTGGGCCTACTGGGC AATGGGCTGGTCGTGTTGACCTATATCTATTTCAAGAGGCTCAAGACCATGACCGATACCTGCTCAACCTGGCGGTGGCAGGACATCCTCTCTTCC TCCTGACCCTTCCCTTCTGGGCCTACAGCGCGGCCAAGTCCTGGGTCTTCGGTGTCCACTTTGCAAGCTCATCTTTGCCATCTACAAGATGAGCTT CTTCAGTGGCATGCTCCTACTTCTTTGCATCAGCATTGACCGCTACGTGGCCATCGTCCATCTGTTCAGCTCTCACCGCTCCGTGCCCGCGTCGTT CTCATCAGCAAGCTGTCCTGTGTGGGCATCTGGATACTAGCCACAGTGCTCTCCATCCCAGAGCTCCTGTACAGTGACCTCAGAGGAGCAGCAGTG AGCAAGCGATGCGATGCTCTCTCATCACAGACATGTGGAGGCCTTTATCACCATCCCAGGTGGCCCAGATGGTGATCGGCTTCTGGTCCCCCTGCT CAACGATCTCTTCAAGCTCTTCAAGGACCTGGGCTGCCTCAGCCAGGAGCAGTCCGGCAGTGGTCTTTCCTGTCGCACATCCGGCGCTCCTCCATG AGCAACTCACATCGCCTACGACGTCACCTACAGCCTGGCCTGCGTCCGCTGCTGCGTCTCCCTTTTCTTGTACTTCTTCATCTCCCCTCTGTTCCG CAACGATCTCTTCAGCTCTTCAGGACCTGGGGGCTGCCTCAGCCAGGGAGCAGCTCCTCAGTGGTCTTCCTGTCGGCATTCCTGCGCCCCTCCATG AGTGTGGAGGCCGAGACCACCACCACCTTCTCCCCATAGGCGACTCTTCTGCCTGGACTAGAGGGACCTCTCCCGGGTCCCTGGGGTGGGGATAGG GAGCAGATGCAATGACTCAGGACATCCCCCCGCCAAAGCTGCTCAGGGAAAAGCAGCTCTCCCCTCAGGAGTGCAAGCCTGCTCCAGAAGTTAGCT TCACCCCAATCCCAGCTACCTCAACCAATGCCGAAAAAGACAGGGCTGATAAGCTAACACCAGACAGACAACACTGGGAAACAGAGGCTATTGTCCC CTAAACCAAAAACTGAAAGTGAAAGTCCAGAAACTGTTCCCACCTGCTGGAGTGAAGGGGCCAAGGAGGGTGAGTGCAAGGGGCGTGGGAGTGGCCT GAAGAGTCCTCTGAATGAACCTTCTGGCCTCCCACAGACTCAAATGCTCAGACCAGCTCTTCCGAAAACCAGGCCTTATCTCCAAGACCAGAGATAG TGGGGAGACTTCTTGGCTTGGTGAGGAAAAGCGGACATCAGCTGGTCAAACAAACTCTCTGAACCCCTCCCTCCATCGTTTTCTTCACTGTCCTCCA AGCCAGCGGGAATGGCAGCTGCCACGCCGCCCTAAAAGCACACTCATCCCCTCACTTGCCGCGTCGCCCTCCCAGGCTCTCAACAGGGGAGAGTGTG GTGTTTCCTGCAGGCCAGGCCAGCTGCCTCCGCGTGATCAAAGCCACACTCTGGGCTCCAGAGTGGGGATGACATGCACTCAGCTCTTGGCTCCACT GGGATGGGAGGAGAGGACAAGGGAAATGTCAGGGGCGGGGAGGGTGACAGTGGCCGCCCAAGGCCACGAGCTTGTTCITTGTTCTTTGTCACAGGGA CTGAAAACCTCTCCTCATGTTCTGCTTTCGATTCGTTAAGAGAGCAACATTTTACCCACACACAGATAAAGTTTTCCCTTGAGGAAACAACAGCTTT AAAAG HUMAN SEQUENCE—CODING ATGGACCTGGGGAAACCAATGAAAAGCGTGCTGGTGGTGGCTCTCCTTGTCATTTTCCAGGTATGCCTGTGTCAAGATGAGGTCACGGACGATTACA TCGGAGACAACACCACAGTGGACTACACTTTGTTCGAGTCTTTGTGCTCCAAGAAGGACGTGCGGAACTTTAAAGCCTGGTTCCTCCCTATCATGTA CTCCATCATTTGTTTCGTGGGCCTACTGGGCAATGGGCTGGTCGTGTTGACCTATTTCTATTTCAAGAGGCTCTAGACCATGACCGATACCTACCTG CTCAACCTGGCGGTGGCAGACATCCTCTTCCTCCTGACCCTTCCCTTCTGGGCCTACAGCGCGGCCAAGTCCTGGGTCTTCGGTGTCCACTTTTGCA AGCTCATCTTTGCCATCTACAAGATGAGCTTCTTCAGTGGCATGCTCCTACTTCTTTGCATCAGCATTGACCGCTACGTGGCCATCGTCCAGGCTGT CTCAGCGCACCGCCACCGTGCCCGCGTCCTTCTCATCAGCAAGCTGTCCTGTGTGGGCATCTGGATACTAGCCACAGTGCTCTCCATCCCAGAGCTC CTGTACAGTGACCTCCTGAGGAGCAGCAGTGAGCAAGCGATGCGATGCTCTCTCATCACAGAGCATGTGGAGGCCTTTATCACCATCCAGGTGGCCC AGATGGTGATCGGCTTTCTGGTCCCCCTGCTGGCCATGAGCTTCTGTTACCTTGTCATCATCCGCACCCTGCTCCAGGCACGCAACTTTGAGCGCAA CAAGGCCATCAAGGTGATCATCGCTGTGGTCGTGGTCTTCATAGTCTTCCAGCTGCCCTACAATGGGGTGGTCCTGGCCCAGACGGTGGCCAACTTC AACATCACCAGTAGCACCTGTGAGCTCAGTAAGCAACTCAACATCGCCTACGACGTCACCTACAGCCTGGCCTCCGTCCGCTGCTGCGTCAACCCTT TCTTGTACGCCTTCAICGGCGTCAAGTTCCGCAACGATCTCTTCAAGCTCTTCAAGGACCTGGGCTGCCTCAGCCAGGAGCAGCTCCGGCAGTGGTC TTCCTGTCGGCACATCCGGCGCTCCTCCATGAGTGTGGAGGCCGAGACCACCACCACCTTCTCCCCATAG

[0296] TABLE V MOUSE NOMENCLATURE ICSGGG CCnd1 CeleTA TnCG212S1 HUMAN NOMENCLATURE HGNC CCND1 Celera hCG279S5 MOUSE SEQUENCE—GENOMIC CACGGGATCCAAAACCCTCTCCTGACTTCTGCAAGCGCTGCACACACATGGTACATAGACATGCACACGCACGTGCGTAAACATGCTGGCTTTCTGA TCCTACGGCTTCTAATTTAGCACTAACACTTAGACTTTTTATTCCCTGTTGCTGCCATGACTGACCCCAGACCCTGCCTTTCAGGCTTCTCCTTGCT TTTCAGACATGGGACAGTTCTGGGGTCTCTTTTGCAAATTGAGACCTGTGCTCACCTAGCACACATGTGGCCTTGGGTTCCATCCCCAGAACTGAGT GAATGAGGCATGGTGGCTCACCCTGTGATTCCAATATTCAGAATGTGGAGACAGTAGAATGAAGAGTTCCAGTTTCAGGTACACCAAACCTTGTACC AGAAAGAAGAGGGGGAAGAGAAGGAAGAGGAGGGACAAATCTAGCAAAAGATGGAGGAAGCATACAGTGACTTTGAAGATGTGTTAACTTTCCCTTG CTGTAAGGAAATACCTGCGGTAATTAACTTATAAAGAACAGAGGTTATGTGAACTCACAGTTTGGGGATTTTAGTCCAGAACAGGACTCTATTCTAC TTCGAGTCTCTAATGCAGATGATGAGAGCGAAATGCTGAGCAAACAGAACTGAACTGCCCTGTACTACATGGCAAATCAGAGGAAGAGTAGTCCCAT CGTCCTCTCTGAGGCCACCTTCAGTAACCTAAGGACTGCCAGGCTGTGCTGTTTGTTTGTTCTCTGTCTCTAGGGTGTTTCTTTTCGGGTTTGTTTT GGTTTTGTTGGTGGTAGGTTTTGTTCATTTGCTTGTTTGTTTTTGATATAGAATCATGCTATGCAGCCCAGGCTGTTCTCAAACTTGTAATCCTCCT GTCTTCGCCCCCTGACTACTAGGATCACAGTATGCGCCACCACACCTGGCTCTAGAATCCATCTCTTGGAAGTTCTACCACCTCCCAATAAAGCCAC CCTGAGAATGAAGCCTTGGACAACCAGAGAATATTGCTGAGCCAAACTACAGCAAGAAGGCTGACCAGAAGGCTCTGCCAAATTCACAAGCCACTGG CCCATCTGCAATAGATGCCATCTGTAAAGGAGTCACTTCTCCCCAGGGTGACAGATTCAATGCAACCTCAATCAAAACCCTAGCTGTGGTGGGTTTG TGTGTGTGTGTGTGTCTGTGTGTGTTTATGTGTGTGTCTCTCTATGCATATCTGTGTGTGTGTTGGGGGTGCTAACCTGTGTCTGTGCATGCATGCA CAGTGTCTGAGAAAGAGGGTCCAAGATGCCGGCCACTGTAGGCCATGTTACTGTTCGCATGGGACAGGCCTTAAAGAAGAGCTGCAAAAGAGCCTTG TACCCACCTCCTCCAATGAGACCCACCCCAGTCTGCTTTCTCAGTTAATCTCTTCCTCTCTCAACTTGAAGCCTGTCTGGGAATTTGCTGTTGAGTA GATTATAGGCTTGGCCTCAGCTGGTCCACTAAAAGCAGGAGGTGAGGGCCCAGGCCTGAGGAAGCATTGGGGAGGCAGATCCCAGGCCTAAGTTTGT TGGAGACACATTCTCCAGGACCACAAATAGCTGACATGCTGTTACCAGATTGTCATCCCAGTACCTGCAAAGTGGGAGAACCAGAATCAGGTGTTCA AGGCCAGCCTCTCAAAAAACAAAACTGAAGTAAGTACATCAACTCTACTCTGCCTTTTAAGAGTTAAAAAGGGGCCTGGAGAGATGACTCAGCAGTT AAGAGCACTGGCTGTTCATCCAGAAAGACCTAGGCTCAATTCCCAGCACCCATATGGCAGCTCACAACTGTCCATGACTTCAGTTCCATAATTCCAG GGGATTTGTCATGTTCACACAAACATACATGCAGGCAAAACAGCAATGCACATAAAAAAAAATAAATCATAAAACAAACAACAAAGAGTTAAAAGGA CAGGAGAAGAGGAACAAGAGAAGGTTCATGTGGCCAGGTTTTCTTTTCCCCAATTTAAAAGTTTCTTCTGAGGTTTACATCTCACACCCATAAAGAG CTCAGAAGTCAACAAAGCGAGGAGGCTTGATTCATCATGAAGTCATTTCAAAATTTCTCTTTCTGAATATAAACCAAAATATTTAATTAATTCCACA TACCACAGGAGTACATTACACCCTTCAAATTCACTCTGCTTAACAGTAAACTCGTGAACGAATGCACAGAACAGACCCCCAGTCACCCACCAGCACT ATGCTAAATGTCCTATGCACATTACCTGAATTACTTCTGGCCATGGCCTGGCAGAGGAAATCATCCCACTGCCCAGCAGAGATGAGGGCATCTTTGC CCACAGCCTCTCCAATGCCAGAGAGCACAGCTCTGTACGTTGCCTCCTGTAGTTACAGAAATGTTTTCCAACTTCCTCGCATCCTGAAAAGAAGTGG CTTGCCTTAAAGTGACTTTTCTTTTTCCTTTTCACAAACAGTGCAGGATGGCCTCCTGTGCCAATGACAGGTATGTGCTACCTCATCTAGTTCTGGT AGTACGTGGATTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAAG AGAGAGAGTGAGAGAGAGAGTGTTTGTGTACCTGTTCTTTCTTGTGTATCTGTGTACCTGCTCTTTCTTGTGTGCACATATGTGCACCTGTTCTTTC CTCTGTGTGTATGTATCAGCTCTTTCTTGGGGGGGGTGTATGTCCCCCTGCTTCTGCCTTACAAGGGCTAGTATCTCAAGCAATGAGTTTGGTGGAG TTACAGATGCCTGTGTCCAGCTCTCTATGGATTGTTAAGCTGCTAACCTCAGCACACTGGTTTTCTGCCCTGTCAAATGCCTGCGATGACAGCATCC ACCTGGTAAGCTGGAAGGTGGGGTCTGCTCCTCCATCCCACCTGAGAGGGAATGATTTCCTTAGATAGGCTGCGGCTGGAACTCACCTGATCTAGAA GTACACTGGGGGCACACAGGAGCCATGGAGCCCCTAAGCCCCACCAGCAGCTTCTGTCCTATCCCTTCTGGCAAAGGGGCCATCTGTCAAAGGAGGG GTTGAAAGATGGCCCAGAAGAGGTCTCCTCAAATCTCTGACCCTTACAGGACTCTGATGATAAATGATACAGTCTCAGTAGGCCTATCCTGGCTTCA TTTCTTCTGCTGTGATAAAATGTCATTGGGGGAAAAAAAAAAAAGCAGCTTAGGGAGAAAGGGCTTATTCTGGCTCGGAACTCCAGGTTTCCAGTCC ATTACTACATGAAAGGCAGTGTGGCAGGAACTTGAAGCACATGGTCACATCATATCCTCCCAGAGCAGTGAGATATGAATCCAGGGGTGGGGACTGG AATGATGGCTCAGGGGTTAAGAGCATCGGCTACTCTTCCAGAGGATGCCGATTAAAACTGTTTGTAACTCCAGTTCCAGGGGATCTGACACCCTCAC GCAGACATACTTCAAATAGACATACATGTGGGCAAACACCAATGTACTTAAAATAAAAATAAATAAATTATAATAAATAAATAGGTGCTTAGTTACT TTTCCCACCTTTAATCAGTCCAAGACCCAAGCCTAGGGAATGTGTCACCCACTCCCACACTGGGTCCTCTCACATCAGCTAAGATAGCCAAGACACT ACCCACAGCCGTACCCATAGGGCTTCTTGAGACTCTCTAGCAACGTGAATCGAGGTTGTGTCAAGTTGACAATTGAAACTATTATGGTGCTTAACTG CTCCCTGATGAACAGGATGTGGCAGAGACAGGCATCCCATTGGTTAATGTCAGAAGTGTCATCCCTCCGTGGACTGAATTTTTGCCTTTAACTTATA TTTATTTGCTTGTTTGTTTATTAGTGTTTGTATCTATGTGCATGTGTGAGTGCGGCTTCCCTCAGAGTCCAGAAGAATGTGTAGAATCCCTCTAGAG CTGGAGTAGGGGGCTGCCGGGTATGGGTGCTGGAAATCAAACCCGGTCCTCTGGAAAAATCAGCAAGCACTCTGACCTGTTAAATCATCTACCTAAC CTCATCCTTGCTCATGTTTTAAAAATAGTTATAGTGGCCAGGTGGTGGTGGCGCTCGCCTTTAATCCCAGCACTTGGGAGGCATTGGCAGGAGGATT TCTGAGTTCGAGGTCAGCCAAAGTGAGTTCCAAGACAGCCAGCAGGGCTATACAGAGAAACCCTGTCTCAAAGAACCAAAAATAAATGAAATAATTA TAGTGGGTTTTTGGACATTCTCTGTATGCTAAGCACCTTCCAGATGGGCTTCCTGACAAGAGATCCGTGGCCTGACCCACACTGATTTGAAATAATG ATGAAAATTCAACTTTCAGAAGCAAAGGCTGTAGTTCCTCTCTGGCTTCTACCACAGTCAGTAACCAGTCCAGTTCCTTAGAGAGTCAGTCACCTTA GTACACATTCCAGCGGAGCCAAGACAGTATAGTGCTCCTTATAAACATGGAAGGGCAGTTCCTACCCAGCGAGTCACTGCCGGCTTGGTGCCTCTAC TGAAGCGCAGCCTCAACCACCCTTCACCGCGGGGAGCGTCCTCAGGCTCTCGCGAGCCACTGCTGCGCGTCGCGTCCAAGGTTTACGGTAAGCGCGG CGCTCAGGACGACCACGTGGCGGCGAAACACCGGCCGGCGGGAATGCGCGGAATGCGCGGTGCGGCCTCGCGCGCTCCCCAAGCCGTGACCCCGGAG TTCCCGGCGCGCGTTTGTGGGACCGCGGAGGCTAGTGCCATGGGTCCGCCCGCGCGTCCAAGCCACCAAGCACCACAGGGAGCAGGGGCCCCATGGA GGGCTCAGCACGTGAGGCTAGACAACCTTTTCCAGGACCTGGGGCTAGGTTTGCCCTCCCTGTTTGGGCTCCATCACAGATCTGGAACCCGCTTAGT CCCCATTCTAAAGCCCCCACTGATCTGGATTAAGAATGGAGATGCCTGGTTTTGCAGGGAAGCAGGTCCCTGGGCTCTGCGCCCTGACCGCCCTTCG GAGTGCTGAGGGACCAGTGCCAGGGGCTGAAAGACCCCAGTTCCAGCAGCTGCGCCCTGGGATCGCATGAGGGTTCGCTCACCACGATTGAGCCACG TGGTCCTGCCTGGCCACTGGTGGCTCACCTTGGCCCGAGTGCCCGCTCCCCACCATTTAGTCTGGGAAGGGCCGAGGGCCAAAGCCCATAAGGACCC TAGGGTTCTTCAGAGCACCTGTGATTCGTTCAGAGAGCTGGAGACCGAGCAGACATCCCTCCTTCAAATTGCATCTCTACCCTTGGGGGTCCCTGGA GCCAGGCTTGCCGCTCCAGAGCTCATTGCACGGCGCGCGTCTATTCGCTCTGGGTGGTGGGATTTAGGGACTGAAACTTATTTGGTAAGGCACGCTT GGGAAGATAGGATGCGACGGTCCCAGGTGTGCACAGGGGATGAGCTGAGCATACACACCTTAGCCGAAGGGTGCCTGAAATCCGCTCAGGGTAACCT AGGCGGAGCAGCCGTGTAGCACGTGGGCTGCCACGCGCGCCCCAAAACGCCTTCTGGGTGAGGAGAGGGGAAGCCGTTTGCCTCCGGAACCTTGGGG TCCATATTCGGAAGTGTTTTCTCTGGGCGACTTGAAGGCTAAATTAACAATGGCTAGCTGGAGCAGAAACAGCCAAGTCCTTTTCAAGTTGCGCCAG GTATGCGGCTGCAGGTGACCCCACCTAGGTGCGTCCGCTCTTCTCCAGGAGGGGCTACAGCCAGAGGCTCAGTATGCCGCCCAGCCCCGCACCCCCT AACCCGAGCCCCGCGCTTAGTCGCGAGGGTTCCTCAATGAACGCGCTCCCTCCCACTTCTCAATGAAGTTCCCACAGCCAGGGATAGTGGCAAACGC AAGACTAAATCTCCGCTCTCTTTGGAACCTTGGCTCCAGTCAGGTGGGGGTAGGGGTAGGGTTCGAGGAGGCAGGAAATCCGAAAGGGGATTAAAGT TACTTTGAGATTTTCTTTCCAAATAACGTGGTTCCCTCTCGGCTGGGCAAGTGGCCTTTTGTCTCCAAAAGGTCACTGACAAATAAGCGCAGAACAC TTTAAGCCCAGAGCGGACAGTTCCTGCCACGAGATTTTTTTTAAAGCCAATGTAAAGTTAAAATTGCAAAAGAAAGTGGGTGTTTGTGTTTAAGTTA CTATTTCGCTGGAAAATAAAAATCCAAGTTCTTTCTCTGAGATTCCTAAAGCAGTTGTCCCGGAAAGAACTCTGAATTGCAGCCCACCTCCTGGGCT CGGGATTCGGACAAGCAGGGTTTCCAGGATGGAGGATGGGCGCTCCCCGCCGGGTCCCAAATTCCTGCGCCTCCCCTACGGGTTCCTGGACGGCTCT ACACGCCCGCCAACCGGACTTGCACTTTGCTCCTCTCCCTGAGCGCAGAGCTCAACGAAGTTCCTCGTGGGAGATCTGCCCGGTCCGCCTAGTAACA GCACTGAGTCCGGATTGGCTCATGCAAATTTCAGTTTCCTGGTCTTTCCCGCGGTGGCGGTGGTGGGGGGTGGCTGCGGGTCGCTAGCTCGTGCTGC AGGTGGGCGAGCCCCTTTATGCCCCGCTGCCCTTGGTGGCGCACCCTGGCTAGGCTAGCCTGCTCAGTTCGCAGGGCACTCAGCCGCGGGTGATAGC GCGCAGCCCTATAAATCATGCTTACTGCCGCCCGGTAGGGATTTTATGAATGAAAAGGCAGCCTGGCCGCCCTCGTGCTTAGGCTAAGGCTCCCAGG CTTGGCGGGGCCTGTGGCCATAGCAGCGTGGGCACTCTGCCCGGGCCACCCCACCACCTTCGGAGCTACAGTGGAATCACTGTCCCGAAGGGTCCGG ACTTTAGGGACCCCAATGTCGGGGGAGGGGGAGCGGAAGGCATGAGCTCGGAAGQTGAGGGGTTTGCGTCTTGTGTGCCGCCTGGACGCCGTGCGCT CCTTTACCAGTTTCTTCTGGGACACGAAAGTATTCCGTGGGAAATGTGTGTGAATAGTTCGCCTAGCTTGAAGTCGGGTATTGTGAAAACGTTTCCA AAACTAGGGAACTAAATAATGGACGAAGGTGGTGGAACCGCTTTATTCTAAAAATATTTTATTTGAATCTATAAATTATAAACTTAGGAGTCCATTC AGTTAACCACGACCATCTATAGATTCTCTTTAAATATCACCTTATCGGCTCACAAGTTTATCTTGATTCTCACCAGCCGCCCCCCCCCCCCAACTCA AGACTGCAATTCTAAAGGTGGAGAAACACCACCACCCTCAACGAAGCCAATCAAGAAGCTTCCGGTTGTCTGGTTCCTGGAAGGGCGACTAATAACT TGCAGCGATTTACTTTTCTTAATTAAAAAATAAATTAGGAAGGAGCCTATCGTGTCTCAACCTTTCTTTCAACGGTTTATTTTTCTTGGGCAAACCG CCTGCAGTGGAGGAGGGGGATACTGGGGGACCCTGGCCAGGATAAACCGGTCACTGTATGAAGACAAATCTCAGATCCCACCCCACCCCCCAGCGAG GAGGAATAGATGAAATAATGGCCACCATCTTGAGCTGTTGCTGGAATTTTCGGGGTTTTATTTTATTTTTGAGCGAGCGCATGCTAGGCTGGGGATC CTTTAAGTTCAGATACCCCTCTGGCCCTTTGCAACCACCCCAGTGCGCCAGGATGGAGCCTGCACGAGAGTTTAGGGCTCGTCTGGCATCTTTCGGG TGTTACACAGTTCCTGAATTTTACACGTGTTGATGAAATTGAAAGAAGACAGGGACGCTGGGATTTCTAAGCAATGGGTCCGCCTGTGGGTGCCTCG TGGCGTCCTCGGAAACGCACCCATTCTCCCGGTTTAAGAACAGGGTGTCCTTGCACCCCCAGGCTCCCCTTCCATACATTCTTCCTTGGCTTGCGTT TGGCCTGGCCTCCCTCCTGCTGTCCTCCTGTCCAGAGCCGCCACTACCCCACCTCCACAGGGTCTCGGAGGACCCTCTTAGGGAAAGAAGCCCCCCT CCCCCTTGCCCCGCTCTTTCCCAGTTTGGAGAGAAGCAGTCCGAGCGATTTGCATATCTACGAAGGCTGAGGGGGAAGGGNNNNNNNNNNNNNNNNT NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTTTATTGCAAAGCAAAAAGTGTTTATTAATAATTGGGGCAGGGCAGGGAGCGGCAG TAGGGGCGCTGGGACAGGCACGAGGGGCCTCGTGGCGGCCGGGAATCACTAAATAAGACAGTGTGAGGAATATTTGGGGTGGGGGATTCTTTGTTCA AACAGCGGACCTGGGTACCCCGCACACGCTGCCTGGCCCAGAGAAAACGCCAGGCTGCAAGGTCGCGTGGCCCCCTAGTCAATGAGACTGACTGTTG TGCGTGCGGTTCTGGATTTGGAGGAACCTGTCTAGGTCAAACTGGGGGCGGAGGGGGACAAAAGCACATTTTCAGATGTTCAGCAGGAGACTCAGGG GTCCCAAAATATTTTAAAATAATTTTTAAAGTGAGGCATAATGCCCTTGTAGAGGCAAACAGCGCCCGCACCCTGCAAAAGGGGGGCCCCCCGGAGT TTGAGTTGCTGGAGCTCACCCCCCAATGTCCACTGAGCTCCTGACCCTCGGCTTGGATCAAGGGTCGTCCGATGGTTATTTTCAGGTCGTTTTTAGG CACCTAGTTATTTTTTAAATATTTTTAAATATTTTTTGAAAAGATGACGTCTGGGAAATGCAGCGCGGCGGCCTGGGACGCCACCATTGTGTCTCGC GTGCGCTCGAGCGGCGCCCAGCCCCCGGCGCCCCGCCAGCCCCGCGGTGGGGTTCTCTGGCTTGTGGCTTCCTAATTTCAACAGGGGACCGGGGTCT CCGTGGCCACCATTGCTTCTACCGGCCCCGCCAGCTGCCCAAAGACTTTCCCTTTCAGTTTCAGGGTGGGIGGGCACTGGGAACCCTCGGAGCAGGA GCGCATCCCAGGGAGTTGGCCACCGGAATCCCTCTCTGTGCAATCTAGGAAAAGGGAATGGGGTCGTATCGAGCGACGCCCCCCTCCCACGTTGACG GTCAGGGTCCGGATCCCCGCAGGTCTGTGAGGAGCAGAAGTGCGAAGAGGAGGTCTTCCCGCTGGCCATGAACTACCTGGACCGCTTCCTGTCCCTG GAGCCCCTGAGAGAGCCGCCTTGCAGCTGCTGGGGGCCACC1TGCATGTTCGTGGCCTCTAAGATGAAGGAGACCATTCCCTTGACTGCCGAGAAGT TGTGCATCTACACTGACAACTCTATCCGGCCCGAGGAGCTGCTGGTAACCACGTAACCCACCACCGACAATCCCTCTTTATGCTGGGTGGTGGGAGC TGCAAATGGCAGGAGATCCAGCCATCCATGGACAGATCTCCTGCCCCACGAAAGGCACCCGCACCGCACCGCACGACACCGAAATGGCAGTGAGCAG CCCCCTAGCGACGTGCAGGCCACGGCGCTGGCGGTGGGAGATTCTTTTTGTCCGCAGTCTGTCCCCTTAGTATTTCTACAGGCACATTTTGTTGTTT ACCTGTATGGGGTCCCGGGTTGACCCAACTCTTTAGACCTTCTCGAATCAGCCTGCCTTCCTTTTGACCGTGTTCCTCATTCTCTGCAGCAAATGGA ACTGCTTCTGGTGAACAAGCTCAAGTGGAACCTGGCCGCCATGACTCCCCACGATTTCATCGAACACTTCCTCTCCAAAATGCCAGAGGCGGATGAG AACAAGCAGACCATCCGCAAGCATGCACAGACCTTTGTGGCCCTCTGTGCCACAGGTAAGGCTCCACCCCCATTCTTCCCAGGAAGAGCGGGCTCCT TGCCACTCCCCCTGGGGTTAAGGCCTCTTTTCCTTGCTATCTATTCTGAGCCCAGGGTGCAGATAGTTTGTTGGAGAGATATATGATACTGGGTGGT CATTCTCTTGGCTAGTATCTTGGAGACCTAACAGAATGACACAGCTTCCCTGTGCCAACCTTTCCACTGCCAGGAAGTGGTACGGCCACAGCATGCT TTCTGAAGAGGTTTTTGCCTCTTTTCCTAGGCTTCCTGCCTTGCCTCTGTTCTTAAGGAGCTCGAGCTATAGAGCACACACACACACACCAGCTTCT CCCAGCTCTGAGCCACCTGCTAGGGGTTCCTACATGGATGGGACAAATGGTCCAGCCTCAGCCCACGAGCTACATACAGTACAGCCCCAGAGCAGGA ACTTTAGAGGCCCCACCAGGGGTACTGCAGGCCAGTACTTTTTGGCTGAGTCCTGCCTGGGAGGGTTGGCTGGAAACAGAGAAACTAGAACCTCCCT ATGACTCCTCCAAGGGACCCTCTCTGGCCCCAGACCCCAGGTAGATTAGGCTGACATAAGTCATGGTAGACAGCCATGCAGGAACCCACACACATAG ACAACCCTGCTACTTCTGAGTGGTTTCAGTACTACTTCTGACAGCTGCTCCTCACCTCTAACTGAGAACCCTACCCAGGAGGCTTAGCAATATTGAG GGGGTGTGGTGTTCTCCCACCTGTTGAGGACCCCCTTCCTCTGTGGCCCTGATCAGACCTCAGTTGCTATAGCTGTTTGGCCTGTGATGTCAGAAGG GCCGGTTGAGTATCTCCCCCCACCCCCAACCTCCACCTCACCCCCGCTGTCTCAGTGACATCTTCTTATGTCTGACAGCCCCATAGCCAGTGTTTCT AAGCTGCTGGTGTGAGAATTTGGAAATTCTAGCTTGCCAACTACCTACTGAGAGTGCTGAGCCCGCCCCAAGGGTACCAAACAAGGGGGTGGCAGAT GGGAGTAGCAAGGCCATCGGTAGGCTGGCAGGATCTAAGGGGTGGGGGTGGCCCTGCTGTCAGTCAGGGAGGCAGCTGGCTGGGGTTCCTCTGAGGA GAGCGGAGCCTTTGGAAGCTCCAGGCAGCCTTTTATGGAGCTGAAAGTGCCTTCAGAGAGGCAGCAGAGTTTCCCAGAGATAACTTGGGGATGGAGA GCTGGACTCAGCTCTTCCAGCTCTCCTTACTGCCTTTGTGCCCCCTGGAAATACAGGTGGGGGGTAAAAGGACAGCTTGGTGACCTGCGGTAGGCCA GTGTTCTGTGGTCTGGAGCATTTGTTTCTCTGTAGGAGCAACCAGCTCCTTTGTCACACGGGAACCACTTTTGGGAAGAGGCCAGTGTGACATCACG TGAATGGAAAGATGCTAACATCAAGGCCAGGAGATCTGTCGTCTGTGTGACAGGGGTTCCCCCTATAGGAGATGGGAAGGCATAACTTCCCTTCTGC AAACCGCCCCCCCCCCAACCTGGATTCCTGACTGCAGTTGAACAATGTGCTAGCTAGGGTTGGGGTTGTTAACACAGGTGGCCAGAGCGCTGTGTGG ATGGATACAGACAGTGGGAAACTGAACTTAATGAAGTATGTAGGTGTCAGACATGCCACTAAGCCAGGGTACACCTATGTCATCAGCAACCAGTGTT AGTAGCTAGGGATCCTTATAGGACATAACAGATCTTGCTACTGCCCGTGGGAGGGAGAAAAACAGGCTCTGGAAGGGGCTGGGGACTCCTGGTCCTG CTGGCTGGAGTCTCACTCCCTGTAAAAGGGCTGTTTGTGATTTGAACTTGACTCCATAGCCAGGTTTTGGTTCACTGGACTCACTAGCATGAACTGT CCTTGGTGACACCTGGAGGTATTGCTTGTCTGCTGGATCCCTTTAAACAGCCTGTATGTTCTCTCAGGGGTGGTCCCCAGAGGGGGGCCACCTCGCT ACAGCAACTCTCTGCCTTCCTGATCCCATTCCTTCCAGCCTCCTTGATCCCAGGCTCTGGGTGACACACAAGATGATTGATGGGAGCTGACATCTGT TCATTCTTGTGTCCTCCTCTGGCCTGGAAGCCCTGATTCGCAGGCCAAGTGACCAGCTGTCCCTGTCACTATTTCTTTGTTGGACGGGACAGGGAAG CAGTTTTCAGACTCATCTTTGGTGGGTTTATGCGGAGAGGCATTCCATCGGTGTGACATACAACTGCAGGATGCTGAGTCCAGTGGACCTGAGAGGT GTGGAGTTGGTGACCCCAGATGAAGTCCTAAAATGACACCCCACTACTTCCCAGTTGGGACATGTACATATGAGAGTCCCTAAGACTCCAGGGCCCC TCATGAGGGACCTTGGCCTGGAGATCTGAGGTGGCTATTCCCAGCTCCCTCTGAGTCTATTCCTACTGGGTTTTCCTGGACTGGGGTCACATGTCTT CCCCAACCTGGGTCAGTAAGCCGGGAAGGCTAACTCCCTTCTGTGGAGTCTAGCCTGGCCTCTGAGGAACCTGGGCCTGTCATCTCTACAGCTTTCT CCTGTGTCTGAGATGTGTCTCTAGTCCTTGGGGTGCTGCCAGGCTGACTCTGGAAGAGACAGAGATCCCTGCCTCCCACCTCAGCCGCGCAAATACT GGGATCCAGATGTGAAAGCACCACACCTTCATAGATTCCATCCTCTTAGGGCGACATAGCCAACCCCTCCTTGATGTTTGCTGGAAGTGCTGGGGAT TTGAACCCGGTGTGTATGCCAGGCAGCATTTAAAGTTTGAGCCAAGGCCTTATTGACAGGTAGCATCAAGGCTCTGGCCTGGACACCGTAATCCTCC TATGTGCTGGGGTCTAGAGATGCAGCACTGTGTGCACCTAGTGCCACTTAGGTGTCTCCAAGGGAGCTAGAGTTGATGTGGGCATCCATTGGAAGGG CTTGAAGACCAGCCCCGAGGCTGTGGGTGGGAGCTGAATCATAGGCATGTCTCTGTCCCTCTCGCTGTAGATGTGAAGTTCATTTCCAACCCACCCT CCATGGTAGCTGCTGGGAGCGTGGTGGCTGCGATGCAAGGCCTGAACCTGGGCAGCCCCAACAACTTCCTCTCCTGCThCCGCACAACGCACTTTCT TTCCAGAGTCATCAAGTGTGACCCGGTGAGTAAGTCTCATCAAAGGAGGCTACAGCTGGCAAGGGCCTGGGAACCTTGGTGGGCAGTGCCAAGGCAC TGTGTGACTGGGCTGGAGCTGAGAGGTGCCAAATCTGGGTCCCCACGAGCCTCTTCCCAGAGTCATGGGTCCCAAAGGCATAGAGGGCTGTGGTGTG GTGACAGTGCCCCTGCAATGTGTATGGCTAGTGGCATGTGAAGCCCGGTCTGGCCCAGCCAGCATAGGACCATATCTCCCTCAGTGCAGACGTTGGG GATTGAATCCATAAAGGACTCTGGTATAGACCTACACATTCTAGAACTTTCTTTGTGTGAGAGAGGGGTTTGCATCAGGCAGACTGTGCTACGTCTA ACTGTACCTTTCTGCCAGGAGTACAGCTGATCATCCTTGGGGCTCTGGCCGTGAATGTTTTTCTCAAGGGCATCACAAGTTGGCATAGACAGGCAAA AGTCCAGTTCTGGCTTGAACTTCAGTTGGGGGTTCAATGGAGGTCAGAGCCACTGGCATGTGGAAGGCTTCCAGGTGTGACAGCTGTTCTGCCCTGC CTGGCATCAGCCACAGGGACACCCCGTGCCCCATTCCTACATATCTCAATTGTAGAACATGCAGCCCCCTTCCCCTAAGTGTCTGGGGCTCCTGAGA ACTGAGAATAGGGTATGTGGGCAGGTTGGAGCCCACAGGCTTCAGAGAGGGAAGGGTGTCTGTGGGTCCATACTAGGCTACTTGGGCCTCACTTTCT CCATCTGTGAATTGGGGCCATTGCCCTTCCATCCTCTAGCCATGGTGTTCATCAAACAAAGGGGGAACAATACACAAGTTTTGAATGTGGGGGCTTC CCAGGTGTTCCCCAGGAATCCTCCTGGCTTCAGGAATATAGACAGTGCCCTAGCTTCAGCCTGCCTAGGCAGGGCTTCAGTTCATGAGTCTTATTCC TGGGCAAATGCTTTCCAGACCCTACCTGTGCTGGAGCTGTCCTCTCTCAGAGGCCACCCAAGGCAAAAAGTTATGAGAGATAGACGCTCCTTGTGGG GAAGTTCAGGGTACAGCCTGGGAGGAGGAACCTAGAGAGTAGCAGTACCTTTCTAGTCTCTGGCAGCTCTCACCGGATTTAGGGGTGGCTTGGGGAG TTTCCTCAAGCCTTGCTCTTAGCAAAGCCTGCCTCGCAGGTCAAGGCCCTGGCCACCGGCCTCTGGCTAAACAAGGACCCCCTCCATCTCCGCCCGC CTCTCCAGGACTGCCTCCGTGCCTGCCAGGAACAGATTGAAGCCCTTCTGGAGTQAAGCCTGCGCCAGGCCCAGCAGAACGTCGACCCCAAGGCCAC TGAGGAGGAGGGGGAAGTGGAGGAAGAGGCTGGTCTGGCCTGCACGCCCACCGACGTGCGAGATGTGGACATCTGAAGGCCACCGGGCAGGCGGGAG CCACCAAGTAGTGGCACCCGCAAAGAGGAAGGAGCCAGCCCGGGTGCTCCTGACGACGTCCCCCTTGGGGACATGTTGTTACCAGAAGAGGAAGTTT TGTTCTCTTTGTTGGTTGTTTTTCCTTAATCTTTCTCCTTTCTATCTGATTTAAGCAAAAGATAAAAAAATATCTGAAAGCTGTCTTAAAGAGAGAG AGAGAGAGAGATAGAATCTGCATCACCCTGAGAGTAGGGAGCCAGGGGGTGCTACAAAAATAGAATTCTGTACCCCAGTAATCAACTAGTTTTCTAT TAATGTGCTTGTCTGTTCTAAGAGTAGGATTAACACAGGGGAAGTCTTGAGAAGGAGTTTTGATTTCTTTTATATGTTTTAAAAAAAAAGCTTAAGA AACATTGCTTTAAAAAGGAAGGAAAAAAAATACAGCAAACCATTGTTAAAGTAGAAGAGTTTTTAGGTTGAGAAATGTACTCTGCTTTGCTGAAAAG CCACAGCTTAGGCCCTCAGCCTCACTCCCTGGCTTGCTCAGTGCCTACAGCCCTGTTACCTGATACCTGTGCTTTATCCCAGGGGTGGGCAGACCTC TTAACCTTATAGATGGTCAGTGCGACCTCTAGTGGTCTCATGGCGTGTGGCACAACCCCCCTCCCCAGGGCTCAGCTTAATGTGCCCTCTCCCCCCA ACAACCTGCAGGTTCACAGCGCCAGCCACACAGCGGTAGGGAGGAAATAGTGACATAATATATTCTATTTTTGTAACCTTCCTATTTTGTAGCTCTG TWTAGAGAGATGCTGGTTTTTGCCTGAAGGCCCTGCAGCCTGCCCACATCAGGTTAAACCCACAGCTTTTGTGTGTGGTTTGTTTTGTTGTGTTTTC GAATGGATGGGGGGATGTCCACACACGCATTCAGATGGCTGTACACAGGTTGTAGGGCTGGTAGTATGAGGTGCTTGTAAGTTTTGTTGGGTCAAGA AGAGAGAACTCTGTTCTCGCACCACCGGGATCTGTCCTGCAAAGTTGAAGGGATCCTTTGGTGCCAGCTGGTGTTTGGAAGTAGGAACCATGATGGC ATTACCTGGACAAGGAGATTGGGGACAACTCTTAAGTCTCACACAGGAGGCTTTTAAACACTAAAATGTCTAATTTATACTTAAGGCTACAGAAGAG TATTTATGGGAAGGCTGCCCATGACCAGTGTGACTCAAAGCAATTGTGATCTCCCTTGATTCAAACGCACACCTCTGCCCTGCTGGAGAAGGTTTAG GGCCATGTCTGAGAGATTGGTCTTTTATTGGGCAACGGGGGGGGGGGGGGGGTCCTTTTTAATTTAAACCACAAAGACAGAGATTTGGTCTGCTTGA CTTTTCCCAACCCAATTGGCCCCATTGGAGAGCCATCCAAACTGAGGAAATTAGGGGACTCCAAAAGAGTTTGATTCTGGCACATTCTTGCCGCTGC CCCCAAGTTAACAACAGTAGGTAATTTGCACACCTCTGGCTCTGTGCCTTTCTATTAGGACTTTTTGGCAAAAGGTGGAGAGCGGGAGGCTTAAGAG GGGATGTGAGGGAAGAGGTGAAGGTGGGACCACATGGGACAGGCCACGGCTCCTCTCATGGCGCTGCTACCGATGACTCCCAGGATCCCAGGCGTTC AGAACCAGATTCTCATTCTTTGTTATCTTTCACGTTGTTTTCGCTGCTATTGGAGGGTCAGTTTTGTTTTGTTTTGTTTTGCAATGTCAGACTGCCA TGTTCAAGTTTTAATTTCCTCATAGAGTGTATTTACAGATGCCCTTTTTTGTACTTTTTTTTTTTAATTGTGATCTATTTTGGCTTAATGTGATTAC CGCTGTATTCCAAAAAAAAAAAAAAAAAAAAAAAAACAGGTTCCTGTTCACAATACCTCATGTATCATCTAGCCATGCACGAGCCTGGCAGGCAGGT GGGCGGTTGCCTCCAGGGATCTGGGACCCTGATGGCGATCGTCCTGTCATGCTGGGCCCTTCATTTTTGATCTGGGACATAGCATTCACAGCAGTTG GGCACCTGGATTGTTCTGTTATCGATATTGTACTTGTAGCGGCCTGTGTGCATGCCACCATGCTGCTCTGGCCCGGAGGGATTTGCTCTGAGTCTCC GGTGCATCATTTAATCTGTTAGGTTCTAGTGTTCCGTCTTGTTTTGTGTTAATTACAGCATTGTGCTAATGTAAAGACTCTGCCTTTGCGAAGCCAG CTGCAGTGCTGTAGGCCCCCAAGTTCCCTAGCAAGCTGCCAAACCAAAACGGGCACCACCAGCTCAGCTGAGGCATCCCAGCCAGGCAGGACCCTTG AGGGCCGCTGTGTCCATGGTGATGGGGTGAGGTTTTGGCCAAAAGGCCAAAGACTGGTGGTGGGTCCACGGAATCTGCCCTGTGACATGAAAGGCTT TGAGGGACTCTGGCTGGTGGCCAGGTTGGCTTTTTGTATTTCTGGTTGACACACCATGGCGCTTCCCAGCACAGACATGTGACCAGCATGGTCCAGG AAAAAAAAAAAAGACAAAAATCTAGAAATAAATTGGTAAAATCTCAGCTCACTGTTGTCTGTGTTTTCTGGGAACAGGAGTGGGGGTGATGCCACAG CCATGTGGGGTGGCATCTCTGGCCCTGGCACCAACCTGGGATTCCCAAGGGGAAGGGTGTATGCAAGTGACAGCCAAGAGCAAAGTGGGAGCCTCTG GCGTCAGGGAGGCCAGCGACAGCCACTGATCAGAAGCGGCTCTGGGTCCATCACTGCCAGCTACACCCTCCTGCTTATTTGCAGATGGAGATCAACA GAACCCGCGTTCACTGCCCTTGTCTGGCGCAAATGGGTGTTTGCTCTGGGTGAATCACCGTTTTCTTAGGTGCTGCCAAGCGCCCAGAGAGCCATGC TTAGTGTTAAGGGCCAAGACCCAAGGTGGCCTTTCACATAGTTCTGCAGACCTGAGTGGCCTGGCAAGACTCCTGTGATGTCTTCGGGTGGCAGTTA CTCATGACTAGTATTGTTTCCAAACCCTGTGGGGACAGGTGGCTTTTAGACATCATCTTCTACAAGGTAGCTTTTGGGTCTCAGCTTGGCTGTTTTG GTGCCTGGTGGGCCCCTGCCCTTCTGGAAAGTGGAGGGTGTAGAGGACACCTGGTCTGAGTGGTGCCACACCAATGATGAAGCAGAAAGAGATGGAC GGAGGGAAGCCCACAGTGACCTTGCCAGGCGACCTACTCAATGAGAGTATATGGGAACACCAGAGCCAGAGGTGGCTTATGAAGACACAGTACTCAT CTTGTACCAAATTGTCTGATGGCAGGAATCCAGAAGGTATTTTGTCAGCCAGCTCCATATAACATCCGAGCCCGGGTCCACAGTCACATGGCATCCA GGAGAATGGGCATGGGGCCGTCAGCATTCCAGGAAATGGCCAAAGGCATTGAGGTGGAAGAGTGCTTTCCCCCTTGGTTCTTAGAAGCACTGGGGGA GCGAGCTTATCGTGTCCAGGTAGGCTGACATGAGGAAATCCGCTGGGGTGCAGCAGCCAGGCAGCCAGTGCAGCAGAGTGGTACTAGGAATGCAGAC ACAAATAGCAAGGGGCTAAGCATCCACTCAAAGGCTGCTGCTGCTGCTGCAGCTGCTGCTTTCCACCACTGCCTATCAAAGGTGCTCATGGAAGGGC GCCCAACTGGAATGGGCAAGCATCACCATCAACTGCACAGGGCTCACACATGGTGCCGTCTCTTAACGGTGCAATTGGCTTGTCTCGTCATCCAGTG GTCTGTGATTCCCAGCTGTGGCTGATAGCCAAGCCTCTTTTCTTGGTTTTAGCAGTGAAACCCCAGATACCACTGGCCACTCCAGGCTCCAACCCTC AAGTTTAACTGGTAACACTGGAGGCTAGATCCTCTGCTGGGTGTAGAGATACTCCTGTTCTAAGGGTGATGGTAAAATAGCTTTTGAGGGCCCCTCA GAGATAAGGACTCAGGGAGCCAGCACACCCAACTGTCTCCTCTCAGAAGCTCAATGGCTGGTTCTCTCTCTGCCTCTACCAGCTCCATGGTCCCCTG CCCTGTGTCCTGGCCAGGCTCTCCTTTTGCAGGCGGCCTCCATCCTGCTGAGCCATCCTACCTCTCTCAGCCAAGCCAAGCTCTTGAACCTGCCTGG CCTCTCTGAGCCTCAGCTCCCTGAACTGGAAAGATTGCCCCTGGCTCCCCATTCTGTGTTGCCCCACTGCCTGGACCTGCTCCAGCCTTCCTGTTTG TCCTACAGGACTCACAGTGAATGTGGCCCCTGTGGAGCATGTGGAGCATGACATTGCACAGGTGACTCTGTGTAGCCTCTCCCCTCCTGACTCCACA TCCTAGAACCAAGTGTGAGGAAGTTAGCCTGTTGCCCATGGGTCAGCTCAACTGCTGCACTTTGTCCCAGAAAGCAGGCCAACTTCACCAACCCTAC AGAGGATCTGGGCTGCTGGGGCCCACAAAATGCCAGCAGTGGGAGCTGAGGACTCCAAGGGGTGGGACACAGGCAGAAGAGTAGGACTGTGTGTTCT CCCTGCAGTGCCCCAAAGCCCTGGCCACAACATCCCAGGAGACAGTCAATGCGGGTTGGGCTGTGTGTTTGGTGGCAAGGCTATGCAGGCCACATAA GGCCAGTGCTGGGAGCTGGCACTGCCAAGTGTGCTTGCCAAGCAAACCTGTACTTGAGCTGATAAAGCAGTCTGTTGAGTGTGTGGGGTGGGGTGTA TAGGTAACATGAGGCGGGCATGTTGTATACAGGGCCCCACGTGGGCACAGCACAGTGCTGGTGGGATGCAGTACCCCTAGTTCTGAGCTGATCTGGC CTCTCTTACTCAGGGATGTCATCCCAGGAATGTATTTGATCAAACAGTTGTGCAAGAGGACAAAGCAAGCACAGGANNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNUNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACTAAGTAAC TGCTAGATCCTTGGACTTCCATTCACAGCTGCTACTGAACCATTGTTGGGAATTGGACTGTAGACTGTAAGTCATCAATAAATTCCTTTACTATATA GAGCCTACCCATAAGTTCTGTGACTCTAGAGAACCCTGACTAATACAACATGCATACACATAAAATTAAAATGTGCCAGGCAGTGGTAGCACATGCC TTTAATCCCAACACTTGGGAGGAAGAGGCAGGTGGATTTCTGAGTTTGAGGCCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTACACA GAGAAACCCTGTCTCGAAAAACCAAAAAAATAAAAATTAAAAAAATAAGTAGGTAAATTAAATTAAATTAAAATGTTTAAAAAGAAGAAATCTTGGC TGAATATTCTACAGTTTTTTAAGAGTTTGTCAAACATTTTGATGTTACAATGGCCAATGATGACAGTAGCCCCTCACATAAATACATAGTACACAGG GCAAAAGTGTGCACAGGGCCAGTTCAGAAATTGCTGGAAAATTCTGTCCTGACCCTAAGACAAGTTTCACTGAACAATTTTTTTATGAAAATGGTCG GGCTGGAGAGATGGTTAAGAGCACTGACTACTCTTCCGAAGGTCCTGAGTTCAGGTCCCAGCAACCACATGGTGGCTCACAACTATCCATATTGAGA CCTGACGCCCCCTCCTGGTGTGTCTGAAGATAGCTACGGTGTACTTACATATAATAAATAAATAAATCATCAAAAAAAAAGAAAATGGTCAATTTTT AAAATCAGACATTCTAATATAATACAAACCATAGCTATACTAATTTGACACCTGTTGAGGCCTGAGAGCACAACACATTAAAGACTTGGCTTGCCAT AAGGAACCCGTCATGCCTCTGTGAGAGCAGAGAGCTGTGTACAAGATGGATGGACGTTGTACTTCTTACAATGCTGGTCTGGGTTGAGGGGGTTTCA TTCGGGTGCTGTGTGTTGGTGCAGATGGAATGACCTCGTGCAGTACAGAGCACAGAACCGAGACTGCATTGAAGTCTTGGGATGCAATATAGGTGAG CGTCTAGAAGCACCCTTAGATCTGATTATGCATTTGATGTACTTCATTTTTAGACAGGACCTCACTATGTAGCTTTGGGTGGCCTGGCTGAGTAGAC CAAGCTGGCCTCAAATTCCAGAGGATGCATCTGCCTCTGCCTTCTGGGTGCTTGGAATCAAGGTATGCGTGCCACCAGGCCCAGTAAATTTAATTTT TTCAAATTAATTCTTTTCTCATGTTTAGAAATCTTTTCCTGGTTTTTGTTGTTGTTTGTTTGTTTGTTTGTGACTCCTACATTGGGTTTTTGTGACT CCCATACAGAATTGGGATCCACAGTTTTTAAGAAACTGGGCACTAAATTACCCCTGCCTTATGCAAAGCCCACAAGGACAATCTGGAGAGACCGCTT ATGTGAACAGCAGGAGCTGACTCTGTTCAGGGAGCTAAAGGGTAAAACTGTGTATGCTGGACCACTCCATTTCTGGGGGTTCCTGGCAAGCCTTAAT GTTACTCATCTGGACCTCCCTCTATTTTCAGGCTGTCTTGGGTCTTTACGTTGTAGCTTCTCATGGCCTCCTCCTCAGGGTCCACTACCACCCACCT TAAACAATGCCAGTTCCAGCCTTTCAAGCTGAAATCAAGTGTAAAAGGCCCAGCCATGCTTGAGCAGGCCTTCCCTGCACAAGTTCAACCACAAGCA AACTTCTGAGTGAACTGGGTGGCTAGGACCCTTCCAGAGCAGACTTGGCAGCAGGCCTCTGAGCTTGAGAGCAGGTTCCAAAACTCTTGGTTTCAAG GGTCCGCACCCACTGGCAACAGTAAGGAACCTTCTGGGAGAATGGGCAGCACTTTCAAGTCTTCAATCCTGCAGACACTTGGTCTTTAGGCACTGAT GCAACCTCTCCAATAGAGGACTAAAGGACCCACCATCCATGAAGCATGGGGACAGGCACTCCAGCCCTGCAACCCAGGAATGGCCAGGGTCTTATGG AAAGTGCCTCTGGGAAGCTGACCACAGAAAGGCAAGGAGTGACTTCCCTTCTTAGAATATTAACCTGAGGTCACCCTAACTTCTAGGAAATGTGAGC AAAGCCCTATTCACCCCAGATGGGGCTCCAGTGACAGACCAAAGTATACTTCTGCCACAGCCCAATTTGGTGAACCAATGAGTTTCTAAGTGGTTAG TTGGTTATAGGAGTGTGGGAGACACCCCAGCTACAGATAATGATCTTGTGGGAGTTAAAAAAAAAGGGTCCCCACTTCTAGTATACTCCTGAATCCC CTAAGAGCTCTGCTGCTGGGGACAACCAGGTGAAGTAGTGGCTGGAATCCCAGGGTCCTCCCTGCCTTCTCCCTGTCTGTCACCCCCTTACCATGTG GTTATCTCTGTAACTAGTTGCCACAGCAACCTACCCTACATCATCATTAAGATGGTGGTAGAGTGAACTGAACTACAACACAGAGCCACAGGCTGCT GACCTTTGAGACAGGTTCCTGGTTGTCAGGGCTCTGGGGTCCCATGCCTCATTTTCTCTGTCAGCCCTGTGACTTCAGTTTCCTGAGATACACAGCA ATTTCTAGCTCTGCCTCATAAAGCTGGGGAGCCACTAAGGTCAGTGGGGCAATCTTTCTAGTCAGCACACTTTGGTCATCTCCAGGTGGAACCTCGG TGAACATGGGAGTCTCCCTCCCAGGAAGTCTCCCTGCCACCTCCTCAGGTAACTGAGTGCTCCCCTACCTCTGGGCTCCCAGAAGGTGGCAGCCATT ATCAGAGAGCCCACACGGGGTCTGAAGCATCTGACAGCCCTTCAACACTGCTCCTTCTCTATAAATCCATGCTTTTCCTAGACCTGCTAGATTCTGA CATGCCATAGGCTCAAATGAGCAAGAAACTAGGCTGGAGCAGCAGGCACAACTCTCACCCCACTATGCTTTGTCCCGCCTGGAATTGGCCCTTTACT GTGACCTCCTGCAGTCTCTCCACCAGCCCACGTTGCTGACTACAGTCTGGTACATGTAGACTTAGTGGTATGGGGGAAGTCAGGGCTTTAGCGCAGA ACTGTGGCCCCTTCTTCCAGTTTCCTCATCTCACTACCAGGCAGAGGAAGAGGTTTGGGGGTAAATAGGGAAAATTGGGAGGGAGTGAGCCAGAGTT TCTGGGTGTTTGGTCTCAACACAACTATCCTACAAACATCACCATCAGCAGGGCTGGGGGATGGAGAGGTGGTTAAGGGTGCTTGATGATGCTCTTG AAGAGGACCCTGCTTCAGTCCCTGACCACCATATGACAGCTCACAAGCACATGGAACTCCAGTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGGCAGGCGAATTTCTGAGTTCAAGGCCAGCCTGGTCTACAGATTGAGTTCCAGGACAGCTGGGCTAC ACAGAGAAACCCTGTCTCGAAAAACCAAAAACAAAACAAAAACAAAACAAAACTCCTCACTAACACTAGCTTTATACAGAACTTCAATCTGTATTTA GCTCCAGGCTACAATTGGTCCTGCAGTCACAGTTAGGGATTACATAGTGTCTCTGCAGGCCCAAAGGCCCTTCTGGATCACAGTTTAGACAGACTGC AGGACCATTCTGCCAGGCCCTCTCTCTGTTTAGTTACTTTTCTGTGTTGACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGGCAATTTGCGGGATGA AGGAGTTTATTCTGTCCAGTTTATAGGTGGCATTCATTATGGTGGGAGGTTGACAGTGGAGCCTGAGGCAGATGCTCATATCGCCTTTCCACGGCCG AGTCACAGGAAGCCAGAACAGGGTGGGATGAGTGATAGAAAACAGACCGGTAGTGGGGCACATAGCTCACAGGACATGGTCTGGAGAAGGCAGGGGA TTGACCAGCAGCTCAGTGATTATCAAGGACACAGGTTCCACTGGTACCTGACTCTGCCACCTTCAGCGACAGCTTGGCCACAGCTCCCACAGTTGTC TATGGCAGTCCAAGTAACACCTTCATGGTACAGCATCCAAAAGCAGAGCATTCTTCTGACGACCTATGCCCTCCCCTTTCACAGCAGGTGTGACTCA GTGGTGGGAGGAGGCGGCATGCCCACGTGGCAGAATGGTCCTGTAGTCTGTCTAAACTGTGATCCAGAAGGCCTTTTGGGGTAACCAAAGCATTCTG GGGACTTGATGGGGACTTTGAGAAAGGGTCAAGTGGGCAGAGGTCAAGGCTTGTACAGGAACATGGAAAGTTATCAGGCAAGCGGCTGTGGTGATGC TGATGGGTGGGAGATCTGACACCTGATGTACACAAGGTGAGGGGATAGGAGGTAGAGATGAAGGGAGAGAGAGAGGGAAGAGACAAGAGAGGAACTA GCAACTGATTGATACCTGTAGTGATGTGACAGGCACAGTAGGCCCATATCTGTGTCCTACATCTTGATTGCACCATCTTGGCACTGAATGAGGACTG CTGCAGCTGTCAGTAGAAATGATCCCAGACAGACTACTGCTTTAAAATACACTATTTATTCTTTTTTCTGAATATAATAGGAAAGTAAAATATGGTG ATAACAGCAGCTCAGTTCTCACACCGAAGAGTCCCTGATCCTGGGCACCTGAGAGAGTGGTGCTGAATACCTGAGAGGTAGCCGCCAGGCCCAGGAG GCCAGGTGCATGGTGCCCCAAGCCTCAGACTCAAAACATATTTACAAATCCTTCGGACATACAGCTAGGCTCTATTCTGACTAGATTATAACTGAAG ATAACCCATTTATTTTAACCTGCATTCTGCCAGCTGGCTGGTTACCTGTGCTCAGGTACCATGTGTQCATCTCCTCACATCCTCCCTGGTAGATCTC CCACCTTGCTCTATCCCAGAATGCTTTCTCTCTCCCAGATGTTCCGCCTATTTCCTGCCTAAGCCATAGGCCATAGGCTTTTTGCCACAGGTGAGGC ATCCATCAACACAAAGATATTCTTCTCTACGAAATGCCTGAGAGCACTGTGCCACTCCTGCCAGCTCGTCTTATATCTGCCTGTAAATACCATGCCA GACACACAAGCTGTTGCTAAAGGAAGTRCAGTGTCACCAGGCAAGCCCTACACATTCACAGTGGCGGCCACCAATTAGTCCTGCTTTGGTTTCCAAT AGTTCCCCTAATGCCACTTTTTGTTTGTTTGGTTTTGAATTCACTTTGTAGACTAGGCTGACCTCAAACTGAGAGATCTGCCTACTATCTCTTGAGC CTGCTTCAGCTTCCTCCCTTGTCTCGTCACCCTTGTCTTCTCAGCTGGGCATCCAGAGGCAAACCAAGTCCAGTGGAGCCTGAGTCCTGTGCAGATA GCAGGAATCAGGTCCTCCAGTGGTGTTGGCAATGACAGCGCATGTTGGAGGCAGAGGCACCATGTGGTACTTCAGGGCATGGACCTGGGGTGGGGGC CAGCTCTGCCACCAGGCCCTTAGACTAGATGGGTCTATTTTATCACTTCTAAGCCATAAGGTATCCTCCACCTCTGGCGCTGCCAGAGGGATGGAGT GAACAAGGAGGCCCAAGCATGGCCAGCAGAGGCTCAGCAGGCAGCAAAGATCCTGTCACGGCTTTCCCATGACCCATTTCACATCGGCCTGCCTCTG TGAGTCCCACCCTCAGGGTAACCCTACCCAGGGCCACTCACTCTGGCCAGTGACAAGCGGTCTTTTGAGTGTGTTGCCCCTGTGCAGAAGGCACGGT GGTCAGGTAAGCCACCTAGGCAGAGACTCAGGGAAGAGCCCAAGCTGGTCCTCCCACAGAACAATGGATTCCTCTCAGGCTTGCCTTTAATCACTGT GACACTTAATGTGCAGACATCTGCTCTTCTGTGGGTCCTCAAAACCCAAGTCCAGAGCCTCCTGGAGTCACCTTGAAGTCTGGCTGCACGTTGAGCA GTGAGCACAGCTGAAAGTACCCAAGAGCCCATGCCTTACACCTCCTGCACTTCTGCTCAGCTTTCCCTATCCCAGCACAAGCCCAAAGGCTATGTCG CCTTAACGTCCCCAACCCACTTTCAGTCATTCTACAAGGGCCAAGGAAACAAGTTCCTCTGGGTCTATATCTGGGCACACATTGCCCAACACAACCA TCACATGAACCCTAGGGCCCACGCCAACCTGGCCTTCAAAGCCCCCTCAGGCACACCCCATAGAC MOUSE SEQUENCE—mRNA GAGGGCTGTCGGCGCAGTAGCAGAGAGCTACAGACTCCGCGCGCTCCGGAGACCGGCAGTACAGCGCGAGGCAGCGCGCGTCAGCAGCCGCCACCGG AGCCCAACCGAGACCACAGCCCTCCCCAGACGGCCGCGCCATGGAACACCAGCTCCTGTGCTGCGAAGTGGAGACCATCCGCCGCGCGTACCCTGAC ACCAATCTCCTCAACGACCGGGTGCTGCGAGCCATGCTCAAGACGGAGGAGACCTGTGCGCCCTCCGTATCTTACTTCAAGTGCGTGCAGAAGGAGA TTGTGCCATCCATGCGGAAAATCGTGGCCACCTGGATGCTGGAGGTCTGTGAGGAGCAGAAGTGCGAAGAGGAGGTCTTCCCGCTGGCCATGAACTA CCTGGACCGCTTCCTGTCCCTGGAGCCCCTGAAGAAGAGCCGCCTGCAGCTGCTGGGGGCCACCTGCATGTTCGTGGCCTCTAAGATGAAGGAGACC ATTCCCTTGACTGCCGAGAAGTTGTGCATCTACACTGACAACTCTATCCGGCCCGAGGAGCTGCTGCAAATGGAACTGCTTCTGGTGAACAAGCTCA AGTGGAACCTGGCCGCCATGACTCCCCACGATTTCATCGAACACTTCCTCTCCAAAATGCCAGAGGCGGATGAGAACAAGCAGACCATCCGCAAGCA TGCACAGACCTTTGTGGCCCTCTGTGCCACAGATGTGAAGTTCATTTCCAACCCACCCTCCATGGTAGCTGCTGGGAGCGTGGTGGCTGCGATGCAA GGCCTGAACCTGGGCAGCCCCAACAACTTCCTCTCCTGCTACCGCACAACGCACTTTCTTTCCAGAGTCATCAAGTGTGACCCGGACTGCCTCCGTG CCTGCCAGGAACAGATTGAAGCCCTTCTGGAGTCAAGCCTGCGCCAGGCCCAGCAGAACGTCGACCCCAAGGCCACTGAGGAGGAGGGGGAAGTGGA GGAAGAGGCTGGTCTGGCCTGCACGCCCACCGACGTGCCAGATGTGGACATCTGAGGGCCACCGGGCAGGCGGGAGCCACCAAGTAGTGGCACCCGC AAAGAGGAAGTACCCAGCCCGGGTGCTCCTGACGACGTCCCCCTTGGGGACATGTTGTTACCAGAAGAGGAAGTTTTGTTCTCTTTGTTGGTTGTTT TTCCTTAATCTTTCTCCTTTCTATCTGATTTAAGCAAAAGAGAAAAAAATATCTGAAAGCTGTCTTAAAGAGAGAGAGAGAGAGAGATAGAATCTGC ATCACCCTGAGAGTAGGGAGCCAGGCGGTGCTACAAAAATAGAATTCTGTTCCCCAGTAATCAACTAGTTTTCTATTAATGTGCTTGTCTGTTCTAA GAGTAGGATTAACACAGGGGAAGTCTTGAGAAGGAGTTTTGATTCTTTTATATGTTTTAAAAAAAAAAGCTTAAGAAACATTGCTTTAAAAAGGAAG GAAAAAAATACAGCAAACCATTGTTAAAGTAGAAGAGTTTTTAGGTIGAGAAATGTACTCTGCTTTGCTGAAAAGCCACAGCTTTAGGCCCTCAGCC TCACTCCCTGGCTTGCTCAGTGCCTACAGCCCTGTTACCTGATACCTGTGCTTTATCCCAGGGGTGGGCAGACCTCTTAACCTTATAGATGGTCAGT GCGACCTCTAGTGGTCTCATGGCGTGTGGCACAACCCCCCTCCCCAGGGCTCAGCTTAATGTGCCCTCTCCCCCCAACAACCTGCAGGTTCACAGCG CCAGCCACACAGCGGTAGCGATGAAATAGTGACATAATATATTCTATTTTTGTAACCTTCCTATTTTGTAGCTCTGTTTAGAGAGATGCTGGTTTTT GCCTGAAGGCCCTGCAGCCTGCCCACATCAGGTTAAACCCACAGCTTTTGTGTGTGGTTTGTTTGTTGTGTTTTCTTTCTCTATGTTCCAAAACCAT TCCATTTCAAAGCACTTTTGGTCAGCTAGCTGGAGGCAGTGTTGCTGGTGTGTGTTGGGGGGAGGGGTTCTAATGGAATGGATGGGGTTGTCCACAC ACGCATTCATGGCTGTACAACAGGTTGTAGGGCTGGTAGTATGAGGTGCTTGGGAAGTTTTGTTGGGTCAAGAAGAGAGAAAACTCTGTTCTCGCAC CACCGGGATCTGTCCTGCAAAGTTGAAGGGATCCTTTGGTGCCAGCTGGTGTTTGGAAGTAGGAACCATGATGGCATTACCTGGACAAGGAGATTGG GGACAACTCTTTAAGTCTCACACAGGAGGCTTTTAAACACTAAAATGTCTAATTTATACTTAAGGCTACAGAAGAGTATTTATGGGAAGGCTGCCCA TGACCAGTGTGACTCAAAGCAATGTGATCTCCCTTGATTCAAACGCACACCTCTGCCCTGCTGGAGAAGGTTTAGGGCCATGTCTGAGAGATTGGTC TTTTATTGGGCAACGGGGGGGGGGGGGGGGGGGTCCTTAAAAAAAAAAACCACAAAGACAGAGATTTGGTCTGCTTGACTTTTCCCAACCCAACCCA ATTGGCCCCATTGGAGAGCCATCCAAACTGAGGAAAATTAGGGGACTCCAAAAGAGTTTGATTCTGGCACATTCTTGCCGCTGCCCCCAACTTAACA ACAGTAGGTAATTTGCACACCTCTGCCTCTGTGCCTTTCTATTAGGACTTTTTGGCAAAAGGTGGAGAGCGGGAGGCTTAAGAGGGGATGTGAGGGA AGAGGTGAAGGTGGGACCACATGGGACAGGCCACGGCTCCTCTCATGGCGCTGCTACCGATGACTCCCAGGATCCCAGGCGTTCAGAACCAGATTCT CATTGCTTTGTATCTTTCACGTTGTTTTCGCTGCTTTGGAGGGTCAGTTTTGTTTTGTTTTGTTTTACAATGTCAGACTGCCATGTTCAAGTTTTTA ATTTCCTCATAGAGTGTATTTACAGATGCCCTTTTTTGTACTTTTTTTTTTTAATTGTGATCTATTTTGGCTTAATGTGATTACCGCTGTATTCCAA AAAAAAAAAAAAAAAAAAAAAGAGGTTCCCCTGTTCACAATACCTCATGTATCATCTAGCCATGCAGAGCCTGGCAGGCAGGTGGGCGGTCTGCCTC CAGGGATCCTGGGACCCTGATGGCGATCGTCCTGTCATGCTGGGCCCTTCATTTGATCTGGGACATAGCATCACAGCGGTTCAGTCACCTGGATTGT TCTGTTATCGATATTGTTACTTGTAGCGGCCTGTTGTGCATGCCACCATGCTGCTGCCCGGAGGGATTTGCTCTGAGTCTCCGTTGCATCATTTTTT TCTGTTAGGTTCTAGTGTTCCGTCTGTTTTTGTGTTAATTACAGCATTGTGCTAATGTAAAGACTCTGCCTTTGCGTTCGCAGCTGCAGTGCTGTAG GCCCCCAAGTTCCCTAGCAAGCTGCCAAACCAAAACGGGCACCACCAGCTCAGCTGAGGCATCCCAGCCAGGCACCCACCCTTGAGTCCGCTGTGTC CATGGTGATGGGGTGAGGTTTTGGCCAAAAGGCCATAGACTGGTGGTGGGTCCACGGAATCTGCCCTGTGACATGAAAGGCTTTGAGGACTCTGGCT GGTGGCCAGGTTGGCTTTTTGTATTTCTGGTTGACACACCATGGCGCTTCCCAGCACAGACATGTGACCAGCATGGTCCAGGAAAAAAAAAAGACAA AAAATCTAGAAAATAAAATTGGTAAAATCTCAAAAAAAAAAAAAAAAAAAA MOUSE SEQUENCE—CODING ATGGAACACCAGCTCCTGTGCTGCGAAGTGGAGACCATCCGCCGCGCGTACCCTGACACCAATCTCCTCAACGACCGGGTGCTGCGAGCCATGCTCA AGACGGAGGAGACCTGTGCGCCCTCCGTATCTTACTTCAAGTGCGTGCAGAAGGAGATTGTGCCATCCATGCGGAAAATCGTGGCCACCTGGATGCT GGAGGTCTGTGAGGAGCAGAAGTGCGAAGAGGAGGTCTTCCCGCTGGCCATGAACTACCTGGACCGCTTCCTGTCCCTGGAGCCCCTGAAGAAGAGC CGCCTGCAGCTGCTGGGGGCCACCTGCATGTTCGTGGCCTCTTGATGTGGAGACCATTCCCTTGACTGCCGAGTGTTGTGCATCTACTACACTGACA ACTCTATCCGGCCCGAGGAGCTGCTGCAAATGGAACTGCTTCTGGTGAACAAGCTCAAGTGGAACCTGGCCGCCATGACTCCCCACGATTTCATCGA ACACTTCCTCTCCAAAATGCCAGAGGCGGATGAGAACAAGCAGACCATCCGCAAGCATGCACAGACCTTTGTGGCCCTCTGTGCCACAGATGTGAAG TTCATTTCCAACCCACCCTCCATGGTAGCTGCTGGGAGCGTGGTGGCTGCGATGCAAGGCCTGAACCTGGGCAGCCCCAACAACTTCCTCTCCTGCT ACCGCACAACGCACTTTCTTTCCAGAGTCATCAAGTGTGACCCGGACTGCCTCCGTGCCTGCCAGGACAGATTGAAGCCCCTTCTGGAGTCAAGCCT GCGCCAGGCCCAGCAGAACGTCGACCCCAAGGCCACTGAGGAGGAGGGGGGGTGTGGATTGACCCTGGTCTGTGCCTGCACGCCCACCGACGTGCGA GATGTGGACATCTGA HUMAN SEQUENCE—GENOMIC CATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCGTCT CTACTAAAAATATTTTTTGAAAAAAAAAAAAAAAGAAAGAAAAGAAAAATAGCTGGGCATGGTGGCGCATGCCTCTAATCCCAACTACTTGGGAGGC TGAGGCAGGAGAATCGTTTGAACCCAGGAGGTTGAGTTTGCAGTGAGCTGAGACCGCGCCACTGCACTCCAGCCTGGGAGACAGAGCAAGCCTCTGT CTCAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAGGGGAAAAATCACTCCAATCATCCCAAGTCTCAGCTCCTACTCTTTTGCTATATGTCCTTCAA ACCAGCTATGTATTTATTTTGCTGAATTTATGCTGGTTTTATCTTTTGTATCTTGCTTTTTTTCATTTAATGTTTTTCCATCCAGTGAACACACCCT AATTTGCCATTCCCCTCTTCTTTGAACATGAGATTGTCTCTAGGGTACTCTTGCAAATAGGATAATTGTCAATGATGTAACGGGTCTCTATGCAACT TGCAAAAGTGATCAGTCTTGGTGTCCTCCTCATCCTAGTGTTTGGTTCCAAGCAACAGAAACCAATGCTGGCAGATTTCAGCAGAAAAGGAAAATCA GATGCAGAAGATAGGCAGGAACAAGGGAGGCAAGACAGCACGAATCACAATGGAAGCATGCTGCAGATCTTCTCTGATGAGAAGCCAGGGCTACCCC CTGCTCATAAACTTGAATGCCTCACCCAGTTCTACACTAGAAAACATTTCCTACCTTTCCTGATTCTTCCCACCACCAGCTCCCAATTCAAAATCTT GATCCAAAAAGATGAAATGTATAAATAATACTATTTATAATGACATCAAAATATCAAGTACTTAAGAAGAAATCTAATAAAAGATGCACAACACCCA ACACACACACACACACTCACACACACACACCTGCAATTAAATTAAGGACAATCTAAATAAACAGAGGTCTATATCATGCCCATGAATTGAATGACTC TGTTAGTAAGTGTCAATTCCCTCAAAATTGGATCTATAGATCCAATACAATCCCAATCAAAATTCCAGCATTTGTGTGTGTGCACATGGGTAAGTTG ATTCTGAAATGTTTATGGAGCCCCAAGGGCCAGGAGTAGCCAGGGCAACCATAAAAGAGAAGTGGGTTGGAGGATTTAGCCCGCCAGATATCAAGAA TTCGTAGCGTATAGCTTCCATGATGCTTCTGGGGTAAGGACTGAAAAAGAGACCAGTGGAACGGGATAGAAAGTCCAGAAACAAGAGATTTGTGTTA TATATGTATCTTATAACATCATGCTGTCAAGTTTATTTCAAAAATAAXTTTTACATAAAATCTTAGCAGTGTTATTCATAATAGACAAAAAGTGGGA AAATTCTATTTTTTTAAAGTACAGAAACTTTATTCCTCAAAGGGGAAATAGGTTAATAATAATAAGAAGAAGAATTAAGGCCAGGTGTGGTGGCTCA TGCCTATAATCCCAGCACTTTGGGAGGCCAAGGCCAGAGGATTACTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATAGTGAGACCCCATGTT TACAAAAATTAAAAAATTAGCTGGGTGACGTGACAAGTGCCTATAGTCCCAGCTACTTGGGAGGCGAAGGCAGGAGGATTGCTTGAGACCTGGAGGT CAAGGCTACAGTAAGGTATGATCGTGCCACTGCACTCCAGCATGGGCAACAGAGCAAGACCCTGTATCTAGGGGGAAAAAATGATAAGCCTTTGTGA AAGAGAAATGAAAACAGCATCCACACATAAACTTGTACCTCTGTGTTCATCGGCAGCATTGTCCACAGTAACCAAAGGTAGAAACCATCCTAAGGCC CATTGACTGATGAATGGATAAGCAAAATGTGGTCTATCAATACGTTTGATAGTATTCAACCATAAAGAGGAATGAACCATGGACACATGCCACATGT GGGCCTTGAAAACGTGATGCTAAGTGGAAAAAGCCAGATGCAAGAGGCTGCATAGCATATGATTCCATCTGTTGGAAATGTCCAGAAAAGGCAGATC CACAGAGAAAGATTAGTGGTTGCCAGGGGCTGGGGAAAAGGGGGAAGAAAAGGGTGAATAACTACAAATGGGTACAGGGTTTCTTTGGCGGATGATG AAAATGTTCTCAGATGGTGATGGTGGCTGTCCAACATAACAAAATCCATCGAACTATTTACTCTAAACGAGTGAACTTTACGGTATGTAAGTTATTT TTCAATAAAGTGGTTTCAAAAAAATAAAAAGGTGAACCCTACCATTTCTAGGTGCTTTGGAGTTTACCGTTTTTCTCCTTGCATTCTGGAGTCAGAG TGAGAAGGCATCTCAGCTCTACCACAGCTGAATGATGTGTTGGGCTTCGGTTTCCTCATCTGTAAAATGGGGATAAAGGGCCTCTCCTTGGAGCTGC CATGAAGATTGAATTAGATGCCCTCTGTGAAGATGCAGGGCAGGTGGAGAGCACAGTAAGCGTCTCGGGGGGCCACGCCATCACCGCCAGCAGGGCT CACCAGTATCTTTGCCCAGAGAATAGCCGCGGTCTAGGGAGCAGCCAGGGTCTAGGGAGAAGGGCTGCTTCCCTGTGGAGGCTCCTAACTTTCCCAT CTCCTCCCTGTTTCTCCCCTGCCCACCCCTTTACTCCTGGAAGTGTGACTCGCTGCCTCCTCCCGTGACTCCCTACATTGCATCTCCCCAGTTACTG TCGTTATCTCTCATCTCTTCTTTCCAAACAGCCTCTGTCTAGCACCTTGGAGCTCGCATGGGAATTCATGGGTGGGTGGATTCCAAGCTTGGCTTCA TCAGATGACAACTAAAAGGCAGAGGCCTGGGGGGGCAAGGGAGCTCCAGGATCTGTCTCCCTTTGGAGAAGCCCAGGTTCACCTTCCCAGCAAGCTG CTCCGGCCCCACGCCCCTGGCCCTCAATAACCTTCAGTGGCTCCCTTCTTGCAGCTATAATTCCCCTCTTGGGATGCTACAAAAGGGATTCCAGAGA TTTTTTTTTCATACTCATAAGGGATGGAGTAAACGATATATGTGCCCAGGACAAGGCAGCTAATGGGAGAGGCCTCAGGCTTCCTTTGCCTTTGCCT GGAAGTATACCAACCCGCAGCCCGGAGGGCCAGCAGAGAACCAATGCTCAGAGCCTGGGGGCCCAAGGAATGCTTTCCAGGCTGGCGGTCCCAGGAG CCCCCTCTCCCTTCCCTATAGCAAGATACTAAGAGCAGAGGCTGGCCTGGCAGGCCGTGTCGAGGCCCTGAGCTCACATGGCCTTGGCAGTTTCTTG ACAGTCGTGTCTTTTTGTTTCCAGCAGTGACACTCACTGACCCACACCTTTGGCCAGCGTCCCTTGTGACTGCCCCCTCCCGCTTGAGCAGAATGGC TCCTATTACACAATGGGTGCCAGGAACCTGGCCAGTCCATCCAGAGACAGGGCAGAGCCCTGGGCTACCGACCCTCTGGGGCCAGCAGAAACCCTCC CTATGGCTCTGCCTCTCATCCTGGCATTTGACACTTGTGCCCTTAATTAAAGTGCTTCTTTTTAAATCAACATTTCTACTCCTTTTGCAGAGTAAGA GAAAGAAGAGTTAGGGGAGAAGAAAGAAGGAAGGATTCATGGGGTTATTTTTTTTTTTTCATGTAAAAGTTTGTTCCGTGATTTAAATCTCATGTCC ACAAACAGCTCAGGAGAAGTCAGCATAGAGAAGCAAGTGACAGATTATAAAGTCATTTGTAAAAATCCTCTTTCTGCATATAAACTGAAAATGTGAA TTAATTCCACATACTGCGTGTGGCACATGGCCTTCATCCTGCATAAGAACAAATACATGAATGAATAAATCGAGCAGGCCTTGACACTCACCAGGCC CTGTGCTAAATGCTTTCTACATATTACCTTAATTACTCCTCACCGTGGCCTTGCGAAGATAACGATCACAGCCCGTTTTACAGATGGTGTCAGAGAT TTGTCCAAGGCCACACAACTAGTGGCAGATGTAGGTCTGTATGTGACATTCTTGTTCAGTTTCATAAATGTGGCTGCCACCTGCCTGAAATTTTGAG GGAAAAAAAAGTGGTTTGGCTTTGCATGAATTCTTGAAAAAGTAGATTTTTATCTTTACCAGCTTCTAAGCAAGCTGGATTTATTCTGACAGTGTCC ATGAAATGGCTACAGACCATCACCGTTGCCATGTTGTGAACCTGAACAAGGCACCTGGTTTCTCTGTGCCTCGGTTTCCTTACCATTTTTTCGCATT TCCCTGAGATTAAGTGTGTGAAACTATAAGTTGGCTGGAGGAAACACCTCATAGAAGTGAGAAGATGAGGATGGGTGGTGAGTGAAGGCTTTTTCTC CAACCCTACAGGAGATGGACCTCAAAGCAAATGGCCATGCTTCCCTTAGACTGGGTGAACTGGTGCTGCTCAGGGCTAGAAAGTGTGTCTAGAAGCA TGGGGACCAATGCAGCCCCCTCCACCCTAGGGCACATAACCTGTCTCTCTCCCATAGGATAGCAGAGACAGCTCTCTAAGTCAGGATTCAGCGAGAT GGTCCAGGAGGGGCCTAAGGATTCCTCTGACTTATCCAAGCCTGGGGAGGCAACACAACCTAGCCTGTGCTCAGGGGGGCCCCAATCATGCCCTGAA CCTCATGAGCCCAGGCAGGCATCCTGTTGGTTAAGGTCGGCCTCAGGGTCCAGGGATGCACTAGATTCTTTATCTTAAAGTGACCCTCAAGAAAAAA AAATAAATGTAGCTATAGGCAGTTTCTGGACGTTTTCCTATTTGTTAAGCACCTTCTTGCTCCGAGCTTTGTTCCAGCCACAGTGCACTGGACGCTT CGGAAGGCTGCAGCTGCTATTTGGTGCTTTACCACCGCTGAGAAGGTGGAATGGTCACGGCCCGGTTCTGTCACTTTCTTCAGCCGGACAGTCGCCT TATTACGGATTCCAGTAGGGCCGAGCACACTCTTCCTGCCCGTCTTTACAGATGAACATGCTATCGCTCCAGCAGTACAACCCCGCCTTATTACGTA AAAAGCAGCCCCTATCTACCCGCAGGGAAGGAGTATGTTCGGCACCACAGCTGGACTGGTGCTCGAGTTTTTGCGTCCTGGGAGGTCCGCATGCGCT CCGGAACCGTAATGCGCGCTTTTTTCTAAGCCTTACGGTAAACGCGGACGCAGGGCAACCACGTGGCGGTGGAACCGAGGCCGGCGGGAATGCGCGG AATGCGCGGCGCGGCCTCGCGCGGTTCCCGAGCCACGGCCCAGGGTCCGGCGGCGCGCGCTCTCGCCTCCTCCCCCTCACCTCTCCCAGCCGCACCC GGCCCTGGCCTGCCACCCAGAACTCGCTGGGCAAGTCGTGCCCCGCGTGAACACACAGAAGGGGCTTGGGGACCGAGCGCGGCCCATCAGTCCCCTC AGACCCTGAGGACCCAGAATTCCCTAAGGGGGTCCGAATCCGAGTCCTGCCCCCAGCCCTTAAGGCACGGGCTCTCCAGGGACCCAGGAAGGGCGCG GGGCATTAGGTACGCAACCCGTTTCCCCGCACCTGGAAAAAACTCCCTTTCCCTCCCCTCCCCCTGCTTGTTGAGTGTGCGGATAACCAGAACTCTA AGGCGCCCCGTAATAACGACCCCGCTGTCCCTCCACCCACCCCCAAGTGCCAAAGCGAGGGATGGAAGCGCTTTCAAGCGTTCCAAGGGCATTGAGG AGCGAGCTGGAGAGGCGCGGGGATGCGGGGTCCTCCCCGCAGTCTTCCGGAAAGGGCGGGGGGAGGGGCGCGGCAAGTCCGGAGTGGGCATGCCGTG GGGCATTAGGTACGCAACCCGTTTCCCCGCACCTGGAAAAAACTCCCTTTCCCTCCCTCCCTGCTTGTTGAGTGTGCGGATAAACCAGAACTCTCTA AGGCGCCCCGTAATAACGACCCCGCTGTCCCTCCACCCACCCCAAGTGCCAAAAGCGAGGGATGGAAGCGCTTTCAAGCGTTCCAAGGGCATTGAGG AGCGAGCTGGAGAGGCGCGGGGATGCGGGGTCCTCCCCCAGTCTTCCGAAAGGGCGGGGGAGGGGCGCGGCAAGTTCCGGAGTGGGGGCATGCCGTC GGAGCCCACGAGGGCCTCAGCGCGGATCCTCCGCCGGAAAACCGGCTCCCGCGAGCCGCCGCCGCAGGTTTCCTAGGCCCGCGAGTCCCCGCAGCGA AGCCCTGCGTCTCCGTCCGACGCGGGGGTCTGCTCAGCCTCGGGTGGGGCCGCGGCCAGGCCTGACTGCGGGGAGAGGGCCGAACGTGACCTCCGAG GTCACCCCCAGCCAGCTTTTCTCTCCTGTGGTCGGAAGTGGTTTTCTTCTCGATCGGGGCGCCTACTCCCCACCCACTTGGTCGAGAGGGCTGGGGC CGGAAGGCCAGGGAATCTCTGGTGGATTTGGGGGTTCATATTGCTCAGGGTACCAGCCGATGCGTTTGAGGGGGGGCGGGAGTCGAGGTTTAGTTCG CCTTTAACCCTCAAGAGTTGCGCCTTCAGCCTCGGGATCCCAGATGCGTCGTTGGAGCCAGGGCCGCCCCCCTACCTGTTGGGTTTGCGTTTTAACT CCAGCGCACACCTTGCCGGCAGCCCTCGGAGCTAGGGGAGGGGTCTCGTTTCCCCGCAGCCCGCCGGACAGACGACTGGGGCACGGGAGGGGCGGTG GCAGGGTGGTCTGTGTGTGGCTGAAACTAATTGATCTGGAGCGGAAACGCACGTCTGCGGTTGGGGCGATGGGGGGGGCGGTGCGGCTGTCCATGTG CCGAGCGTGTGGCTGTCTCGGGTGGGCACTGGGGCCGGATTTCGCCCCGGCCCACCTCGCAGTTTTGGGGCGCCTGGGATCGGCGCTACGTAAGCGA ACCAGAGCTGCCATAGCACGTGGGCCGCCACGCGCACCCCAAAAGCAAGCAGTGTGGGGGGAAGGGGAGCTCGAGCGCCTTCGGAGCCCAGGGGCCG GCTTTCGGAAGCGTTTTCCCGGGCGACTTAAGGGCTTAACAATGGAAAACTCGCGGAGCCTGAGCCAAGTCCTTTCAAGTCGCCGCCAGGTATGCGG CTGCAGGTGACCCCACCTGGGTGCGCCCGCCCGCCAGCCGCCCTGGTGGAAAAGCGGGTGCGGGAGGTCGCTGGCGAAAGGTCGGGACTGGTCCCTG CACCACCCGCCCCCAACCCAAGCCCCGAGCCCCGCGGCGCGCAGCCGCGCTGAGTCCCGGGGTCTGCGTCGCGGCGCGCCGGTTCCTGAATGAACGC GCTCCCTTCCCCCGCCTGAATGAAGGTTCCCACAGCCAGGGACGGTGGCGAACACGCGCCTGCAGCGGAATTCGCTTTCTCCTGACCGACCATCCGC CCAGGCCGCGGTCACCGGGGCGGGGGCCTGGGGGCGAGGAAAGCGTGAAGGTGATTTCAGTTAATTTTGGATTTTCTTTCAAACAACGTGGTTACCC TCCCGACTGGGCCACTTGCGCTTTGTCTCCAAATGGTCACCAAGAAATAAGAACAGAGCACTTTAAATGAGCCCAGAATCCGCAGTTCCTGCTTCGT GGTGGGTTTTAAGAAGACAGTGTAAAGTAAAACTGCAACCGAAAAGTTTTTTAAAGTTGCTTTTCTCTTTGGAAAAAATAAAATCAAAATGCTTTCT CTGCGCTTCTTGAAGCAATGACCCTCAAAAGCCCAGAGGTATTGGCCCCCTCGGGGGACCCGGGGGCCGCCAAGCAGGGTTCCCCCAGGTGGGGGCT GGGCAGCTGGCGCTCCCCGCCGGGCCCCAAATTCCAGCGCCGGGCCCGCAAATTCCAGCGCCTCCCCCGCGGGTTCCTGGACGGCTCTTTACGCTCG CTAACCGGGCTTGCAATTTTGCGCTCGTCCCTGAGCCGGGAAATCAACGAAGTTCCTAGTCGAGATCTGCCCGGTCCGCCTAGTAACAGCGCCGCGC CCCCATTGGCTCATGCTAATTCCAGTTTCCTCTGTCTTTGCGCCCGGGATGGGGGGTGAAGCTCCCTCCTGGACCCAGAGCCGGTTGTGCCGGAGTG GGCGAGCCTCTTTATGCCCTGCTGCCCCTAGCCGACTTCGGCCCGCTTCGCGCCTCGGGCTGGGCCAGGGCGCACGCGGGGCTCGGGGCCCCTCGCC CCACGGGATGGGAGAGGCCGGGTGATAGCTCCGGGCCCCATAAATCATCCAGGCGGCCGCCGGGTCGGGATTTTATGAATGAAAAAGCAGCTGTGCC GCCCTTGTGCGCGGGCTGATGCTCTGAGGCTTGGCTATGCGGGGGCCAACGCGATTGTGGGTGCTCGGGGAGTGGGGGGGGGCACGACCGTAGGTGC TCCCTGCTGGGGCAACCCATCGCTCCCCATGCGGAATCCGGGGGTAATTACCCCCCCAGGACCCGGAATATTACTAATCCTAATTCCCGGCGGGGGA GGGCGCGCGGGAGGAATTCACCCTGAAAGGTGGGGGTGGGGGGGGTCGCATCTTGCTGTGAGCACCCTGGCGAAGGGGAGAGGGCTTTTTCTATCAG TTTTCTTTGAGCTTTTACTGTTAAGAGGGTACGGTGGTTTGATGACACTGAACTATATTCAAAAGGAAGTAAATGAACAGTTTTCTTAATTTGGGGC AGGTACTGTAAAAATAAAAACAAAAGTTAAGACAGTAAAATGTCCTTTTATTTTTTAATGCACCAAAGAGACAGAACCTGTAATTTTAAAAACTGTG GATTTTAATTTACATCTGCTTAAGTTTGCGATAATATTGGGGACCCTCTCATGTAACCACGAACACCTATCGATTTTGCTAAAAATCAGATCAGTAC ACTCGTTTTGTTTAATTGATAATTGTTCTGAATTATGCCGGCTCCTGCCAGCCCCCTCACGCTCACGATTCAGTCCCAGGGCAAATTCTAAAGGTGA AGGGACGTCTACACCCCCAACAAAACCAATTAGGAACCTTCGGTGGTCTTGTCCCAGGCAGAGGGGACTAATATTTCCAGCAATTTTAATTTCTTTT TAATTAAAAAATTTGAGTCAGAATGGAGATCACTGTTTCTCAGCTTTCCATTCAGAGGTGTGTTTCTCCCGGTTAAATTGCCGGCACGGGAAGGGAG GGGGTGCAGTTGGGGACCCCCGCAAGGACCGACTGGTCAAGGTAGGAAGGCAGCCCGAAGAGTCTCCAGGCTAGAAGGACAAGATGAAGGAAATGCT GGCCACCATCTTGGGCTGCTGCTGGAATTTTCGGGCATTTATTTTATTTTATTTTTTGAGCGAGCGCATGCTAAGCTGAAATCCCTTTTACTTTTAG GGTTACCCCCTTGGGCATTTGCACGACGCCCCTGTGCGCCGGAATGAAACTTGCACAGGGGTTGTGTGCCCGGTCCTCCCCGTTCCITGCATGCTAA ATTAGTTCTTGCAATTTACACGTGTTAATGAAAATGAAAGAAGATGCAGTCGCTGAGATTCTTTGGCCGTCTGTCCGCCCGTGGGTGCCCTCGTGGC GTTCTTGGAAATGCGCCCATTCTGCCGGCTTGGATATGGGGTGTCGCCCCGCCCCAGTCACCCCTTCTCGTGGTCTCCCCAGGCTGCGTGTGGCCTG CCGGCCTTCCTAGTTGTCCCCTACTGCAGAGCCACCTCCACCTCACCCCCTAAATCCCGGGGGACCCACTCGAGGCGGACGGGGCCCCCTGCACCCC TCTTCCCTGGCGGGGAGAAAGGCTGCAGCGGGGCGATTTGCATTTCTATGAAAACCGGACTACAGGGGCAACTCCGCCGCAGGGCAGGCGCGGCGCC TCAGGGATGGCTTTTGGGCTCTGCCCCTCGCTGCTCCCGGCGTTTGGCGCCCGCGCCCCCTCCCCCTGCGCCCGCCCCCGCCCCCCTCCCGCTCCCA TTCTCTGCCGGGCTTTGATCTTTGCTTAACAACAGTAACGTCACACGGACTACAGGGGAGTTTTGTTGAAGTTGCAAAGTCCTGGAGCCTCCAGAGG GCTGTCGGCGCACTAGCAGCGAGCAGCAGAGTCCGCACGCTCCGGCGAGGGGCAGAAGATCGCGAGGGAGCGCGGGGCAGCAGAAGCGAGAGCCGAG CGCGGACCCAGCCAGGACCCACAGCCCTCCCCAGCTGCCCAGGAAGAGCCCCAGCCATGGAACACCAGCTCCTGTGCTGCGAAGGGGAAACCATCCG CCGCGCGTACCCCGATGCCAACCTCCTCAACGACCGGGTGCTGCGGGCCATTGCTGAAGGGGAGGAGACCTGCGCGCCCTCGGTGTCCTACTTCAAA CAACTTGTTGCCCAGACCCACGTTTCTTTGCTACTCACCCCCCTCCCTTCTCTCCCGCTAGAACTTTGAAGTTTGCCGGGGTGTTTCTAGGGATCCG TATTTTCAAAATAAAAAATTGCGGGTATTTTCTGAAGGAGGAAGGGTGGGGGTGGGGGTGCTAGAAGTAGCGTTTCGTGGGAGGGGAGAAGGGGGTC CGGGAGGGGGTGCCTTCGGGGAGAAGCCAGTGCCAGGGGCACCCCAATGGGCCGAGGGTGCGGGCTGGCAGGCTGGGTGCGCTTTGTGTCCCCGCCT GCGCCCCAGCCCCGCTGCGCCGCAGCGGCCGGGAGCCGCCAACTCCGGGGGGAGGGGGGGCATAGATTTGATTTTTTATTTTTATCCATGGATCGTA TGCAAGGGGCCGCTCGTGCCAGTATTATGCGCCATCTTTGCTCTTTTTATTGCAAAAGTGTTTATTAATAATTGGGGGCAGGGGTGGCCGGGCGGGG AGCGGCCGCCGGGCGCTGGGGCCGCAGCTTGGCCGCGCGGCTGCCGGGAGCCCGCGGGAGGGGCGCAGGACGCGGCATGGGTAGTTTTTGTGGGGGG ACCCCGCTAGGGAGGGGGGGCCTTTGTTCTAGCAGCGAGTCCCGGGCGCCCCGAACGGGCAGCCTGGGCCGGACAGCACGGCGAGCTGCAGGTGGTC GCGTGGCCCCCAAGACGCCAGGGCTTGATCCCCGTCTGCAGGGATATCGGCTTGGAGACCTTCTCCGAGCGAGCCGTGGCCTGGGAGCATTTTTTTT CAGACCTTCGGTGGGCGCCTGAGGGGCCCGCAAGTATTTTAAAATAATTTTTGAAAGTGCGGCGTGGTGCCCTTGCGAGAGTTTTTTCGCCGCCTCG GAGGGTCATTTTCAGGGTTTTTTTATGCACTTAGTTATTTTTTTAATATTTTTATATTTTTTTTGAAGATGACGTCTGGGGGTTTATGCGGCGCGTC GGCCTGGGCGCCACCTTTGTGTCTCGCAGGCGCGGCGCCCAACCCCGCGGCCCGTTCCGCGGCCCCCGCACCCCAGTTGGTGTCGACCCCCAGTCAG AGGAACCACGGAGCTCCAGGGCGGGCCAGGGTCCCGGGGGCCGGCAGCCCGCGCCGCCGCGCACCGCCGCCCAGCTGTGCCCGCTCCTCCCCCACCG TGCCAGCCTCGCGGGGACTTTCCCTTTCAGTTTCGGGGAGGGTGGGTACTGGGGACGCGCGGGGGAGGGGGCGCATCACGGGAAGCTCCTGCCCCCC CCAGCCCCGACCCCCTCGGCGCCCTCCAGACCTGGCGGCCCTGCCAAGCGCGATGGGGGTGCGGGGGCGTGCGGGGGGCGGGCGCGACCTGGCGGCG GCGGTCACGGGCCCCGTGCCCCGTAGGTCTGCGAGGAACAGAAGTGCGAGGAGGAGGTCTTCCCGCTGGCCATGAACTACCTGGGACCGCTTCCTGT CGCTGGAGCCCGTGAAAAGAGCCGCCTGCAGCTGCTGGGGCCACTTGCATGTTCGTGGCCTCTAAGATGAAGGGAGACCATCCCCCCTGACGGCCGA GAAGCTGTGCATCTACACCGACAACTCCATCCGGCCCGAGGAGCTGCTGGTAACCACTGGACCCCGCCGCCCCCGCCCCCCCGCGAGCCGCACGCAC GACCACGGGGCCGGGGAAGTGCAGGCGGTGGCGGCCGGCCCGCCTCTAACATATCTGCTCCTCCGAGGGATGCGGCCCTCCGCCCGTCGGGGTCCCT GTCCGGGGAGCGGGCGGGATCCTAGCCGCCCTCGTCCCGCCGCCCTGTGTGCGCTTGCCTGCGACTCCCACCGCGTTCGCGCCCCGCGGTGTGGCCG AAAAGTGGGCGGCGCGCGCCCTCCAGCGGCTGCACGAGGAGCGCCGCGCTCGGCGTTGCCTCCAGTTCCAGGTGTGGGAGGTTTTTCTTTTGTTTCC ACTTGCAGAGTCTTTTCACGCGGCGGGCGCCTTTTCTGTTTTGATCTGGATTGCGTGTTGCCCCAGCTCCCCTTGAGTCCCCAGCATTCGCCAGCCC TCCCCCTCCAACATCCAGGACCGCACGAGACGCAGGGGCCAGTGCTCTGAGCCGGAGGTGCGGCGTGGCCCGGCCCCGTGCTGCCGGCTTCCCCGCG CCCCCGGGCTGGCCCGCACCTCCCCTGATGGCCGCTCACCCTGTGTTCGCAGCAAATGGAGCTGCTCCTGGTGAACAAGCTCAAGTGGAACCTGGCC GCAATGACCCCGCACGATTTCATTGAACACTTCCTCTCCAAATGCCAGAGGCGGAGGAGAACAAACAGATCATCCGCAAACACGCGCAGACCCTTCG TTGCCCTCTGTGCCAAGGTAGGGCAGGCCCGGCAGCCCCCGGCCTCCCCCCCTTGATGCCGGCTCCTTAGGTGACCCTTCCGGCTTCTTGCTCTCCA CCTGGGTGCTGTCTGGGAAGATGTCCCCAGACCCCTCCTGCGCTGGAGAGCGCTCTTCCAGCTCTGGTGAGCAGAGGCCCTGGATTGTTTTGTCGCG CTGGATGGAGGGAGATTTGCTCCCTCACGGCCACCATGCAGTACCTTGGGCATTGGTGTGGACGGCTCAGCCTGCCTGTGTCCCGTTACTCTGGCCT CGTCCTTCAGGCCAGGCAGCCTGTGGCCACTCCATGCTGAAAGGGGTTTACCTTGGCCACAGGGCCGCCCTCCTTTCTCCACCACCTCCAGCCCTTC TTGTTCCTTAAGGAGCCTGAGCTGCAGAGGCCCCCCTCCTGGCCTCTCCCAGGCTGGGCCACCTGCCAGAGGCGCCTCCAGGGGCGGGGAGAGCTGT CGGCCTGCCTGCACCACGTGCTCTGGGCAGCGAGTGCAGGGGGTGTCCAGCAGAGGAGCTCGGCTGCCTGAGGCCCTGCCAGGGGGTGCCGGAGCCA GCCGGGCTCAGCTGAGCCCTGAGGGGGCGCTTCAGAGCACTCTCAGCTTGGGCCGCCACCGTGGGCAGCAGAAGCACCCAGTCCTCACTTCCCCTGG CATGGCCCCAGAGGCCCCTCCCTGACATGGCCTTGGCCCCAGAACCCAGTGGGGACAGACGCGCACATACACAGGGTGCCGCCTCCTGCTGTCCCCA GCCCTGCCTCTGACCCCCCTGTGACCGCCTCCTTCCCTGGCCCAGGAGGCCTGGTTACCTTCATGGGGGAGCATGGCCCCATCCCACCCAGCTCTGC TGTGGCCCACCTTTGGTCAAGCCTCAGTTGTCACATCTGTTTGGGGGCTCACTCTGGGTGACCTAGGCCACAAGGCCCACGGGGCATCAAAGAGGCA GTAGCATCTTCTCCCCTCCCCAGAGGGCAGAGCCCCCCAAGCCTACTTCAGAGCTCCCTTCTGACACCGGTAGCCCGCAGCCGGTATTCCAGAATGG GTTCTGGTTTAGGCGTGAGGCCTCCCCCACCTCCTCCACCTGCTTGGGGCATGAACCCCTCCCCCACGTTTCCAAGCGAGTCCCCAAGGTGGGCAGA TGAAGATGCCAAGGATGTCGACCAGTCTGGATGGGTCTGGGGTGGGGGGGCATGCGGCAGACAGGGAGGCATTCTCTGGCTGGTGCTCCTCAGAGGA GAGAGCCTCCGGAGACTCCAGACAGCCTTTTATGGGCTGAAAGTGGCTTCAGAGAAATGCAAAGTTTCCTGGAGAGAACGTGGGGGCGTGGTTTCTT TCACAGCCTCCCTACAGGGTGGCTCCAGCAGTGGAGCTCCCCTCCCAGGACCCCTGGGTGCTAGTGGGAGGCTGTGGGCAGGTGCAGATTCTCGTCC TTCCCACTACTGCACACCCTTTGTCTGCGAAGGCGCCCCCAGCGGTGGGTGAAGGAGGAGGGACACTTGGGGACCCAGCTGTGCACGTGCTCTCAGT GACTGTGGAGTCCACTCCAGGGTGGGTCCCGAGGGAGGGGCAGGAGACCAGGGGACCCACCCCTGCAAAGTGCTCCGGGTCCTGACCCGTGGCCACC CCATGGAACGTAACTGAGCAGCCAGTGCCTTGTTCCTGCTGGACATCTGTGGAGACAAGAGTGACTTACGGCGGCTTAAAGTCAGAAACAGGTTGAA GGAGGTGGAGGCGTGGGAAGAGTCTAGGAAGGTGTTTTTGCCCTCCACGTGGCAAAGGTTACATTTAAAGGTGATGCTGGGTGTTCTTCCCTGCACT AGGCATTCCTGGCCCCAGGTCCCCAGCAGGTGTGCACATGCTGCATACACTCACGCATGGGGGTTTCAGGGCAGGTGCGCCCTTGGCTCCGTGGGAG GCCAGGTGAGGAACGTCCAGTGCCAAGGAGCTTCCGGGACAGCTGTCACTTCCCTTTACAACCAGGCACCGGATAGGGTCAAATCCTGGAGCTTTGG TTGTCTAATTCTGGGTGGCTCCTAATCTAAGCACAGACAGCACCACACACTGGGTGGGGGCACGAGCTTCTGAAACAACGTGGCCCCAGTGACTCCA CGCTGTGTGTGCCCCTGGAGACGGGGGGTGCACAAGGTGCGGAGCCAGCTAGAACCTGTCGCTCCCTGCAGAAGCGGTTTTCTGTGTGCGGTTCTGA TTTTGCCTCAATGAGAAGGTTTTCATTCATGGCTCCCGGCTCTCAGACTGGGTGGAACTGCTCCCATTTAAAGGGGAAAGAGGTGGCTCGGCTCGTT AAGGATTTTCTTTTTCTAAGTTGTTTACGGCGCCCAGCAGCCGGCTTTGTCTCCCCTTCAGGGTGGCTGCCTTTCTTCCCGCCCTCGCCGGCGGCCC TCTCTTTAACAAGGCCGAAGTTGTTTATTCTCTCGGGATGAAGTCTCGGATGGGCCGCCACACCCCTGGCGGCCCGTGGGGGCCCCTCTCCCTTTGT GCCTGGGTCGGCTCCCATTCAGCTCCCCCGACCCCCCTTGTTCCCGGGCGCTCAGTGGCGCGAGATGAGGCGATGGGGCCGACAAAGATGCCACACT CATCCCTGCCGACCTCCGGCTCCCAGCCCAGGGCCCCTGGTTCCTGTGCAGAATTCCTCGTGGGTGTGACAAAAGGCTGCCCCCAGGCTCCGCTGGG GTGGGGGCCAGGCCAAGAGGCACATCCCACACTGGCCCACCTGTCCACGGTAGGCGCATGACTGCCCTGAGGAGGGGAGGCCGGCATTCCCCGCCAC AAACCAGGACGTAATTGGTGGCAGGGCTCTCTGTGGAAAGAGCCAGTCTGCTGTTTGTCTAGGAGGTCAGTCACAGAGGCCCCGAGACGCCCACTAC TGCAGCCTGGCAGGCGGATGAGCCCAGTATCTGGCAGTGACCAGAGGGAGTTTTGTGCAGACCACAAAGGCTGATGGGCTGCCCTAGATTGGTGTCC CTCTTGGAAGTGGGCCCAGATGTGCGGGACAGTCCCCAGGAAGCCCCAGGTGAGGGCACTGGTGCCCTCTTGGGAAAGCTGCTCCCTCCTGGGGCCC GGCTCCCGGCCCAGTCCTCCAGGGGTGTCCCATGGTGACTGGTGCTAGGAACCCCACACCTCTTCCCTTACTTGGGAAGTCACTGGAATTGTTGGGC TACATCAGACGGCCCAGAAAAGTGTTTTTGTCATCGGCCAGAAATAGGAGAGTTGTGAGTAGAGGGCCCGGGTGGAGTTGGGGTGTACTTGGTCTGT GCTCTGAAGGTCACTGTGACAGTCATGGTCCCATGGTAAGGGGCATGGGTTGCTGGAAGACCTCTTCCTTCCCGAGTGAGCCAAGCCGGGCTCTCCT GGCGCCAGGGCCTGAGCCGCAGCCACACCACAGCCGCCCTGAAGGCTGCCGGCCAGGGCTTACCCCTCAAGGGACACGGAATGGCTTCATCAGTACC CTGCAGCCCCGTGGCCTGGCCCGGGTGGAGGCCTAGGCTTCAGCCATGCGATGTCCCTTCAGAATATGACTTGTCTGCAATCCCTGCTGCTGGGGGG TTGGCAGGTACTTGGGGTGAGGGTTAGGGTCATAGAAGCGACATCTCTACGTCCTCATATTTGCGTCATCTAATTTGTTTTTGTGAATACGTGATAA CATTCACAAGGCTCAAGATGCTAAAAGGATGAGAAGGCAGTGATGTCCCCATCACCTGTCCTGTGTCTTCCCGTGGCTTTCTCTTTCCTTGGTTATG TTTGAGTCAACAGTGCGGCTGACGTTCCAGGAGGGTCCGTGGGCCAGGCTCTTGCTCTCCGAGTGCCCAGGGATGGCTGGAGGCTGAGGAGGGCCTG GATGTGGAGCCTCAGATACCAAGTGCTTCCCTTCAGGCCGGGCCGCTTGCTCAGAGCCAGCACACAGGGATGCCCGGATCACGGGGGCCCTGAGAGG GTCCCCTGCTCACAGCCTCCTTCCCTCTCTCCTTCTGCCTCAGATGTGAAGTTCATTTCCAATCCGCCCTCCATGGTGGCAGCGGGGAGCGTGGTGG CCGCAGTGCAAGGCCTGAACCTGAGGAGCCCCAACAACTTCCTGTCCTACTACCGCCTCACACGCTTCCTCTCCAGAGTGATCAAGTGTGACCCAGT TAGTGAGGGTGATGTCCCAGGCAGCCTTGCCGGGGCTTACAGGGGGAGACACCTAGTGCCACGGAAATGCCGAGGCTGGTGCCAACGCCCCCAAGGG TGACAAGGTTGGGGCTGGGGCTGGGCCCCTCGGACCCCAGGCCACAGACTGACAGGGCACCGGCTTCTTCCACTGCTCCTAGAACTTACTGACTGGC TGGGAGGTCCTCACAGCCTTCTCACGTCCCCTGGGGCTTCCAGGAGCCGTAGAGTTTCTGGGCGAAGCGTCCCGGACGGAGGCCCCAGGCGGCCCCA GCCAATGGTCTGTGTGGTGATGGTGTGTGGGGTTAGGCCCAGGCGAGCTTTGTTTGGGCCACAATGTGCGTGGCCAATAAATAGATGCTTGAAAAGG GCTCCTGTGAGGTCCGAGACACCGGACAACGGGCGGATAGAGACAGCCTTGTTGTTTACGGCCTCTTTGAGAGGCTGCTGCTGTTAAACCCTGGGAT GACTGTGTCTTTCTTCTTAAAAATGCCATTGTTTTATTCCCGAGTCTTTTCTTAAAGAAAGAATTAAAATGACAATCAAAAGGGTTTGTGGCATTTA CCAAATTAGACCAGAGAGGTGGCCGGGTCAGCCGCCGGCCCCGCGGTGTGTGAGGGAGTGACCGCCTGACCCCAGCTTGGGGCTGGGTGGGCCTGCA AGACCCGTTTTGGCTCTGGCCTGGGCCGCCTCTTGGTGGTCTGCCCTCGAGCCTCCCGGGGACTCCGCACGGGTCTCAGCAGATGCTATCTAGGGTC CACCTGCCTGTCCCCTGCCTAGTGGTGCCTCTGTCCCGGGGACACTGGGAGTAGCGGCTGCCCAGCCCATGTGTGTCTCGGAAGAGGAAGAAGCTTT TTTGCCGTGGGACACCGAAGTTGGCAGGGGCCTCCCTTCTGTGTTCTCGGCCATGGCCTCCCTTGCACCCTGCCCCGTGTTATCCTTTGGGGGTGGT GAGGTGTCCTCACCCGCTGTAGGGTGGAGGCCAGCAGCCCGCAGCTCTCTCAGGAAAATGGCTCAGAAACACCATCGAGGCCTCCAGAAGCCCAGCA AAGAGAAAGCCCCTCCATCAAAATGAAACTCGCGTCTGCACTTTTCATTTCGAACTCCACGCCCTGAGTGAAAACCGCTTCCCCGCCAGGGGTGACT GCCCTGGGATGTTGCTGTCTTCGGGCAGTTGTGGGAAGTTGGGCGCTGGCCCTTATTTGAGTAGAGACCATCTTAACTAGATTGGAGGCACACGTCT CACAGCTGACAGACACACGGGGTGAAGTTACCCGAGGCGGAGTCCACTCTGCCTGATCAGCTAGTGACCAACGTAGCTGAGCCCAGACTCAGAAAAA CCGTCCACAGCAGAGGCCCCTGCATTTTCTAGGGCGTGTTCTAGAATTTTCTTTGGTGGGTGGAATGTCCATCTGTGCAAATCGGGTGCGCAGTGCC TGTGGGGCCAGAGGAATGAAGGAAGGTCCTGGAGTCTAGCTGCATGTGTGACCCTGGAGTGGGTCATGGGCGAGGGACGGGCCGCAGGTGAAGAATC CCTGGATGGAGCTGCCAGGCCCCTGGGGCTGAGAATTGAAGCTGGCTGGTGTTTTAGGTTGAACGTCAGGAGTCTTGTATCTCACCCCAGGCCTCTG GCCTAGTTTCCCCATCTGTACAGTGGGACTGTTTGTGCAGCCAGCCCGGCCAGCTTCATTTGCCATGATGAGAATTTATCTGAGGGGGCGGGAGAGG AAAGCCCTCCCTATAAAGGTACAGGCGCTAAAATGTCATGACCTCAGTGGTCCACCTTTGTCGTTCTGTCCTGGGTTATCGCCATGTCGTGCATATG CCTTTGTCCAGCCCCTTCTGGTTGGGAGTTAAGTGGCACCTGTGCGGCACGTGGTGGGGCTGTGGCCCAGCCCTGCTCCTTGTGGAAGGTCTGTTTC CTGGGCTGCCTAGAGACTTGGCTTGAAGCCCTAGCGTGGCTTCCTGGCAGTTGGGACACACACAGCCCCAACACATGGAGCCGGTTCTCCATCCAGA AGCCCCCGGGCAGTAAGCAGCCACTTTCAGGCTGCGTGGGACTTGCCCGTGGTGGAGCCTAGGAGAGGCCCTGGCTGGGCGTGGCGTTCCAGATTTC ACGGCTGCTCTTTCCCACTGACAGTGTGGTGTGGACGCTGCCAAGGGAGTCTGGAGCCCCAGAGGGTGAGGTGCAGGACTTTCCAGGAGCGTCCGTC GCACTCCACCCGAGGGCGAGCACCTCAGTGGCCGCAGTGGGTGGATGCATGCTGTGCCAGGCTGATGGCTGGCCCCCGGGGCACAGGCCTGAGCGGA GAGGATGGAGGGGAGGGATCAATGGTCCAGGTCCCCCCTGGCCACCCCAGCATTCATCCTCAGTCATGCACGGCCCTTCTTCGACAGCCATTGATCA TGGAAGGCCAGGTTCACCTCAAGGGCTGCCACATGGAGAGGTTAAGTCTGAAAAGGCTGAAAAGGCAGGGTTAAAGGGGCCTCCTGTCCAGATCAGA TGGCAGCATCTGGTGTCTTGTGGCTCCAGAGACCAGGTGGGAGGTGGAGGCGTTTTGGGTCCGAGTGTGTCCTACAGGTGATGGTGCTCCCACATCT GGGCAAGCATCTGGTGTCTTGTGGCTCCAGAGACCAGGTGGGAGGTGGAGGCGTTTGGTCCTGAGTGTCCTGACAGGTGATGGCAGCTCCCACATCT CCTCGCTGCAGGCCCCTTCTAAGGACCCCCTCTTCCCACCTCTCCCCACCCTCTCTCTCTCAGGACTGCCCTCCGGGCCTGCCAGGAGCAGACCGTG CCCTGCTGGAGTCAAGCCTGCGCCAGGCCCAGCAGATCATGGACCCCGGCCGCCGAGGAGGAGGTCAGGAGGAGGGAAGGAGGAGGTGTCCTTCTTG CACACCCACCGACGTGCGGGACGTGGACATCTGAGGGCGCCAGGAGGCGGGCGCCACCGCCACCCGCAGCGAGGGCGGAGCCGGCCCCAGGTGCTTG CACTGACAGTCCCTCCTCTCCGGAGCATTTTGATACCAGATGGGAATGCTTCATTCTCCTTGTTGTTGGTTGTTTTTTTCCTTTGCTTTTCCCCCTT CCATCTCTGACTTAAGCAAAAGAAAAAGATTACCCAAAACTGTCTTTAAAAGAGAGAGAGAGAAAAAAAAAAATAGTATTTGCATAACCCTGAGCGG TGTGGGAGGAGGGTTGTGCTACAGATGATAGAGGATTTTATACCCCAATAATCAACTCGTTTTTATATTAATGTACTTGTTTCTCTGTTGTAAGAAT AGGCATTAACACAAAGGAGGCGTCTCGGGAGAGGATTAGGTTCCATCCTTTACGTGTTTAAAAAAAAGCATAAAAACATTTTAAAAACATAGAAAAA TTCAGCAAACCATTTTTAAAGTAGAAGAGGGTTTTAGGTAGAAAAACATATTCTTGTGCTTTTCCTGATAAAGCACAGCTGTAGTGGGGTTCTAGGC ATCTCTGTACTTTGCTTGCTCATATGCATGTAGTCACTTTATAAGTCATTGTATGTTATTATATTCCGTAGGTAGATGTGTAACCTCTTCACCTTAT TCATGGCTGAAGTCACCTCTTGGTTACAGTAGCGTAGCGTGGCCGTGTGCATGTCCTTTGCGCCTGTGACCACCACCCCAACAAACCATCCAGTGAC AAACCATCCAGTGGAGGTTTGTCGGGCACCAGCCAGCGTAGCAGGGTCGGGAAAGGCCACCTGTCCCACTCCTACGATACGCTACTATAAAGAGAAG ACGAAATAGTGACATAATATTTTCTATTTTTATACTCTTCCTATTTTTGTAGTGACCTGTTTATGAGATGCTGGTTTTCTACCCAACGGCCCTGCAG CCAGCTCACGTCCAGGTTCAACCCACAGCTACTTGGTTTGTGTTCTTCTTCATATTCTAAAACCATTCCATTTCCAAGCACTTTCAGTCCAATAGGT GTAGGAAATAGCGCTGTTTTTGTTGTGTGTGCAGGGAGGGCAGTTTTCTAATGGAATGGTTTGGGAATATCCATGTACTTGTTTGCAAGCAGGACTT TGAGGCAAGTGTGGGCCACTGTGGTGGCAGTGGAGGTGGGGTGTTTGGGAGGCTGCGTGCCAGTCAAGAAGAAAAAGGTTTGCATTCTCACATTGCC AGGATGATAAGTTCCTTTCCTTTTCTTTAAAGAAGTTGAAGTTTAGGAATCCTTTGGTGCCAACTGGTGTTTGAAAGTAGGGACCTCAGAGGTTTAC CTAGAGAACAGGTGGTTTTTAAGGGTTATCTTAGATGTTTCACACCGGAAGGTTTTTAAACACTAAAATATATAATTTATAGTTAAGGCTAAAAAGT ATATTTATTGCAGAGGATGTTCATAAGGCCAGTATGATTTATAAATGCAATCTCCCCTTGATTTAAACACACAGATACACACACACACACACACACA CACACAAACCTTCTGCCTTTGATGTTACAGATTTAATACAGTTTATTTTTAAAGATAGATCCTTTTATAGGTGAGAAAAAAACAATCTGGAAGAAAA AAACCACACAAAGACATTGATTCAGCCTGTTTGGCGTTTCCCAGAGTCATCTGATTGGACAGGCATGGGTGCAAGGAAAATTAGGGTACTCAACCTA AGTTCGGTTCCGATGAATTCTTATCCCCTGCCCCTTCCTTGAAAAAACTTAGTGACAAAATAGACAATTTGCACATCTTGGCTATGTAATTCTTGTA ATTTTTATTTAGGAAGTGTTGAAGGGAGGTGGCAAGAGTGTGGAGGCTGACGTGTGAGGGAGGACAGGCGGGAGGAGGTGTGAGGAGGAGGCTCCCC AGGGGAAGGGGCGGTGCCCACACCGGGGACAGGCCGCAGCTCCATTTTCTTATTGCGCTGCTACCGTTGACTTCCAGGCACGGTTTGGAAATATTCA CATCGCTTCTGTGTATCTCTTTCACATTGTTTGCTGCTATTGGAGGATCAGTTTTTTGTTTTACAATGTCATATACTGCCATGTACTTGTTTTAGTT TTCTCTTAGAACATTGTATTACAGATGCCTTTTTTTGTAGTTTTTTTTTTTTTATGTGATCAATTTTGACTTAATGTGATTACTGCTCTATTCCAAA AAGGTTGCTGTTTCACAATACCTCATGCTTTCACTTAGCCATGGTGGACCAGCGGGCAGGTTCTGCCTGCTTTGGCGGGCAGACACGCGGGCGCGAT CCCACACAGGCTGGCGGGGGCCGGCCCCGAGGCCGCGTGCGTGAGAACCGCGCCGGTGTCCCCAGAGACCAGGCTGTGTCCCTCTTCTCTTCCCTGC GCCTGTGATGCTGGGCACTTCATCTGATCGGGGGCGTAGCATCATAGTAGTTTTTACAGCTGTGTTATTCTTTGCGTGTAGCTATGGAAGTTGCATA ATTATTATTATTATTATTATAACAAGTGTGTCTTACGTGCCACCACGGCGTTGTACCTGTAGGACTCTCATTCGGGATGATTGGAATAGCTTCTGGA ATTTGTTCAAGTTTTGGGTATGTTTAATCTGTTATGTACTAGTGTTCTGTTTGTTATTGTTTTGTTAATTACACCATTATGCTAATTTAAAGAGACT CCAAATCTCAATGAAGCCAGCTCACAGTGCTGTGTGCCCCGGTCACCTAGCAAGCTGCCGAACCAAAAGAATTTGCACCCCGCTGCGGGCCCACGTG GTTGGGGCCCTGCCCTGGCAGGGTCATCCTGTGCTCGGAGGCCATCTCGGGCACAGGCCCACCCCGCCCCACCCCTCCAGAACACGGCTCACGCTTA GCTCAACCATCCTGGCTGCGTCGTCTGTCTGAACCACGCGGGGGCCTTGAGGGACGCTTTGTCTGTCGTGATGGGGCAAGGGCACAAGTCCTGGATG TTGTGTGTATCGAGAGGCCAAGGCTGGTGGCAAGTTGCACGGGGCACAGCGGAGTCTGTCCTGTGACGCGCAAGTCTGAGGGTCTGGGCGGCGGGCG GCTGGGTCTGTGCATTTCTGGTTGCACCGCGGCGCTTCCCAGCACCAACATGTAACCGGCATGTTTCCAGCAGAAGACAAAAAGACAAACATGAAAG TCTAGAAATAAAACTGGTAAAACCCCAGCGTGGTGCCTGCCTCTTTGCTTCCTGGGCTGGCCGTGAGCCAGGGACGCGTGTCCTGGTGCCCTAGAAC CAGGGCAGGGTGGCAGGCTTGGCGGATGTGGGAGGCCGCAGCCTGTCCTGTGCGCTGTGGGAAGTTCAGCAGCATCCTGACCTCCATCCCCGGGATG ACAGTCACGCCACCCGCCGTGACAACCAAGAATGTCTCCTGACACTGCCACATCCCCGGGGGTGGGGACAGAATCCAGCCAGGAGCAGGCACACCCC TCCCAACTGGGAGGAAGCCCTCAGCACAGGTGTGTGAGGTGGGAGGCGGTGTCCTGTCCCCGGGAGGCTCCAGAGAATTTTTTGCAGGCTGCCTGGC TGGGTGAGCCCACCTCCAACCACGCGAGACAACAGCTCCGGCCTGGGTGACGTGAGCGGTGCCCATTGATGGGGAACATCTTCCCCCTCTTCCTTGC CCCACCAGTTTGTCTTCCCGGGTTATTTGCAGATAGGAAAATAAATAAAGCCGGCATTCGTTAACCCTCTTCTGGCGCAAACTGCTGTTTGCTCTGG ATGAATCATGGTCCTTTGGCGACGCCAGGCTCCGGGAGAGCAAAGCACCGTGTCAGGGCCATGATCCGGGGTGGCCTTTCACTGGGATCGTGGGGAC CTGGAGGCCGCCTTATAGGACACCCATGACGCCCACCTCTGGATTTCAGGTGCACGTGACTGGACTTAACTTCAAACCCCAGGGTGGAGGCAGGTAG TGGGAGTGCCCTGGGAAGGTGTCCTCGGACCTTGGTCACTGCTCCTGAACCCATCTGTGAGGCTGGTTTGTCCTCATCCCAAGCTAAGTGGAAGCTC AGGTCCCAAGCCACCGATGGGTGCTACTTGTCAGCTGCAGGTTGAATCTCCGTGGCCTTTATGAAGCACCTGCTGTCTACCCTTCCTGCCTTGTAGA GCACTCCTCCCAGGGCTCAACAGTGGGGCCGGGGTGGTCGGTGGGTTGGCTCCACAGGCGCCTGCCCTGGGAGGAAGGTGGGGTGTGGAGGGAAACC CTGGCCCCTGTAGGTCTCCACCAGCCTCTCCCCTGAGGGTGGGGGGCTCCGGGAGCCTTCCTCGAGGGAGTCCTATATTGAGTGGGTGGGGGAGCCT GCAAGGTGCCCCTGACAGGTCACATCAGAAAGAGCTCAAGGGACAGTCGGAGCCAGAGGTGACACTGGTGGCCACTCGGGTGGCTCACAAGGCCCAG CTCCTCCTTGCTCCTGGCAATTACTCTGAAGGCAGGGACCAGGTCTGCACCATTGCGGCTCTCCAGTTCCAGGGGCAATGGCCAGGTCCTGTGTCAG GGCTGGGGTCCTAGGGAAGCCATGTCCCCACCCCCGGCCTGCAGCTGGGTTTACATTCATCCCCCGAGAGCACATGGGTGTAGCAGGAGGCCTGTGC AGAGAGCTCCGACCATCGCACAGGGCACCTTTGGTTGTTTCACGGAGCAGGCAAGGGAGCCATCGGATCCTGTTAGGTTTGAGCAAGGATGTGGGGA AGAAGCTGGAGAGCCACTTTGCCATGCAGGGAGAGGAGCACATGGGTCTAGGGATCTACTTTAGTGTTTGGAAGGTTTTTTAAGATGAAAGAGGGAT GTGTAGGCTGATAGGTCTGGCAGAGCCAAAAGGCAGCGACATGTCTACTGGGAGAGATGGAGCTGAGCGCGGGGCTCAGGCAGGGTGGCAGGGCAGG GCCGGGGCCCTGGGTGGGTCAGGTGGGTTCACAGCCAAGTGTGTAGAGAGGGCTTGGGCCCAGAGTGAAGCAGTTGCAAGCTCTCCCACAACCCATT CTCTCTGTCTCGGCATCTGTGGCATCCCGTGATGGGTGGGTCTGTACACACCCCACCCCTGGCTGTGCCACAATGGGGGTGTCTGTACACCCCTCAC CCCTGCTGTGCCACGATGGGGGGTCTGTACACCCCCCACATCCCTGGCTGTGCCACGATGGGGGGTTCTGTACATCCCCCCAGTGATGGGTGTTCTA TACATCGTGGTTATGCCACGAGCTCCAAGGCTGTATCAGTCCGTTTTCACACTGCTAACAAAGACATACCCGAGACTGGTAATTTATAAAGAAAAAA GAGGTTTATAGACTCACAGTTCTACGTAGCTGGGAGGCCTCACCATCACGGCGGAAGGCGGGGGCCCGTCTTCTTCATGGCAGCAGGCAAGAGAGAA TTCAATCACCTCCCACCGGGTCCCTCCCACAACACGTGGGAATTATGGGAGCTACAATTCAAGATGAGATTTGGGTGGGGACACAGCCAAACCATAT CAAAGGCATCGTCTGGCCACTCTAGGCCCTTGTTCCCAACTCTCTCTCCACTGACATCACCTCTGTGCCCTGCTCCCCCTCCTGGGGGATTCAGTTA GACCTCGTCCCTTGTTGGAGTATCTGCGCTACCAGAGGGTGATGGTAAAACTGACCTTTGAGGAACTTCCCAGAGACAAAGCCTTCCGCAGTCAGCT CTCCCTGCAGCCCCCTTCGCAGAAGCCTGTCCTCACACGCCCGCCACCCTACCTGCCCTGCCTCCTGGCCCATCTCCTGCAGCCAGCAGAGTCCTCA TCCATTCTTCATCCTCTGCCCCCAACCCCCAGCCCTTCCTATCTCCCTTCAGCTCCGTCCAAGGTCCCTGGGACTCAGCCCCATCTCTCCCCAGCTT GACCCCAATAAGTCGATGTCTTTGCCCAGGAGCTCCTGATCACCAGACTGCATCCAGCTTCCTGTTCTGCGCTGGTGGCCTCCCGCCTCGGTCCACA GGAACCTTCATCTCTGCTCTGACTGTAAGGATGGGCTCTCTGAGGGCTTCCCCACCCCCACAGCAGGCAGGTGGTTCTGGAGTCTGGGATTGTCATG CCTGGGCACCTTCCTGCTCTGGCTGAGCCCCTCCAGGACGGTTCTCCCAGATTTTTTCTCTGCCTCCGTCTCCCCACCCACCTGGCATATGTGGTCC TAGGAAGGGGGGCCGAATGGAGGGAGGTCGTGTCGGCTCCTACAGGGCAGCCCCAAGCTGCTGGGCTGAGGTGCAGAGCCATGGGTCCAGCCCTGAG CGCATGCCGGGAGCTGATTCCATGGCTGGAAGGGTCGGGGGTTCCCCAGGAGCCCAGACAGCACCTAGAGTTGTTCTTTTGGAGTTGGGTCCCTGAG GGGACAGAGGAAGGAGGCTGGGCAGAGTGGGCACGTGGACTTCGGACGCGCTTGTGGGATAACAGTGGCTAGGGCTGTGCAGAGGGGTGGTGCACTG CCCATGGGGAGTCCAGAGAAGCCAGGTCCAGTGGCAGTGGCATGCATCCGGCAATCCTCCGGCTACCCTGCATGCAGGCGTGACCTCCTTGAAGCAC CCAGGAAGCAGTCACAGCCTCGCTCTGCCCAGCATTGGGGCCTGGCCTCTGAATCTGGTGGGGAAGGCAATGTGTGCCTGCTGGCACCCCGCTCTAT CACCAGTCCCACCATAAGGCTAGTCCCCAAAGTCAGCACTGCAGCCAGGGCCAGCGAGGGCCAGCAAGGGCAGGCCTGTGCAGGGGCTGCAGCGTGG GGTGTGCGTCCCCGCACTCTGGGCCAGCCTCGCAGCTCACAGGGCTCTGTCATCCCAGGAATGTCTTTGTCAAGAGTTTATGCAAGACGAGGAAAGC AAGCCCCAGGACCTCTAATCCGTTCCCACAGTCCCCTGCCCGCCAGGGCCCCACAAGCCCAGCCCACACCGCCAGGCCTGAGCAGACAATAGCAGGC GGACGGGTGGGCGGGCAGCTCTGGGGCCGCTGGCCTTGGGGCCCATCCGGGAGCATTGTCACCGCCACTCACGAGGGCACACACAAGGAGGGCTGGG GAAGAGAGAATGCAGAGCCCTCTGCTGAAGGGGCTTCGGTGGGCCTTGAGCCTTTCAAAGACGGCGGTGTCCATTAATCCTTTTAATTTGCACCTAG CGGCAGCTGAGACAAGCCTCTCAACCGGCAGCCACTTTAAGAGCTGAGTGGTCTAACCCGAGGATCAGCTCCTATTCCAGACCCTGGGCCCTCTGAG CCTGTCGAGGCAGTCCTCCTTGCCTTTGTTTAATCACGGGAGGAATCGCAGCTGGAGGTTACTGAGCACGCACTGTGTGCCTTGTGCTCAACACCGA ACACAGTTTCTCTCTGAGTTTTGCAACGACCCCATGGGTTGGTGACAGGGAGGGGACACTCTGGTGTCAGCCACAGACACAGCCCTGCCCTCCCAGA GCCTACACTCTCCCGCACACAATCATCCCATCTGCTAGGTCTGGGATTGGCAGGTTTTCTGGAAAGGGCCACAGAGAGAGGCTTCAGGCTTTGTGGG CCACAGGTTCTCTTGCCCTGTGCAAAAGCAGCTGCAGCCGCTCTGTGAATGAGTGAGCATGGCTGTGTGCCAATAAAGCTTTATTTACAAAAATAGG CAGCAGACTGGATTCAGGCTGAGGGTGGTAGTTTGCCGACCCCTGTTGTAGATGAGTAAACCGAGGCCCAGAGAGGTAAAGTAACTGAGCCAGGACT GCACAGCTAGTGTGTGACCAAGCCAGCCTGGTGGGTCAGCCTCATGGAGAAGAAAAGGCTCAAGCTTCAAAAAGGGAAATGCACGGAGGCTTCATTG GGCCATTTGCAGCCAGGCCCCACGCACACAGCTCAGGGCCCTGCTTCGCCAGCTCCACCTGTTTCGAGGCTCCCAGTAGGTTGCCCCTGCGGGCGGC ACTGTGTCTTGGCTGCTGGCCTGGAGAAGGGCAGCCAAACAGGCCGGCAGTGGACATCTGAGGGTGACCAGCTGTTTAAAAAGAAAACTCACCGGCA TGTATAGGCACACATTAAGCACACACGTTTTGGAGTAAAAGGCCCTGGGGTTGGATCTCGGATCTGCAGCTTTCCAGCTGTGCGGCCTCATTTCTCT GGGCCTCAATGTTCACACCTATAACATGGGGAAATCCTGCAAGAACACAGCCCATGATGGGGAGTCGTCTCCATCTCCTACTCACGACAACGACCAG CACACAACGGGGGCTCCATAAATCTCTGTCAATAACTGAATTCTTTCTGGGGTGCTGAGGATTCTATGGCTCAATGTGTGTGAAGCACTGCTGAGCA CCGAGCTTGGGGTGCAGTGATCACTCAGGGAACGCCATCATCCCCTCGGCGCATCCGCATAATCACCATCAGCATTCCATGCACTGCCCAGGTCTGG AAGCACAGGCCTCCATGCCACGGCGGCCGCCTGGGTGTTGGCACCAAAGCCGATCTTACTTCCCTCCTTTGGCACATTAAGTAGACAGTTCTGGGTC TTCTTGACACCACGGATGCCCCCTCCTGGTGTTGACAGCACCCAGACTTTGCTCCAGGGAACCACCATTCCCAGATCTGTGGTTTGAGTGGGACCGA ACCCATGCCCAGCTCCAGGCCAGGTCTTCATAGGCTGAAACCCAACTGCACATCCACACCCACCAGAAGAGCAGCAAGTTAATGGATGGGTGAGAAA TCAAATAGAGCCATTGAGTCTTGAGGAGACATTTTCTGGAGCTTCTGAAAAAGATAATGCTTCCCCCTTCCTTAGGATTCCCAGCAGGGAAACACAA GCCCAGGGGTGGCACTGCCCCCCTGCAGCCCTAAGGGAAGACTGAGCTGCTCCCAGGACCTCACAGCGGAGGCTGAGCGTAAGGCCAGCCCTGAGGG AAAGCAGGGAATGGGTCTCCAGACAAACTGCTGGATCAAGCCTCTCCTGAAGTCATCCCCCTTTTGTTCCAGAAGCCAATCATTGTCCTTCATTAAG TCAGTTTGATATGGGCACTGTGTCATTTGGTTTTCAAAGACACTTAACTATTACAGCTTGTGTGTGTTTTCTTTTTTTTTTTTGAGACGGAGTCTCA CTCTCGCCCAGGCTGGAGTGCAGTGGCCTGCTCTCGGCTCACTGCAAGCTCTGCCTCCCGGATTCACGCCATTCTCCTGCCTCAGCCTCTCGAGTAG CTGGGACTACAGGCGCCCGCTACCACGCCCAGCTAATTATTTGTATTTTAGTAGAGACCGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCT GACCTCGTGATCCACCCGCCTCGGCGTCCCAAAGTGCTAGGATTACAGGCGTGAGCCACCGCACCCGGCCGCTTGTGTGTGTTTTCTACCTCTTCTA GATCTAACATGTTATGATTGATATAAACAACAGGAGCGACTGACAAAGTTACCATGTGATCTTGGAATTTCAACATGCCTGTCTTGCTTAGCTGGGA GTTTCCACAGGGTCAGGGAATGACTCCTCTTGGGCCACCAGTGCCCAGAAGTATGCCTAGAACTGCTCTGTCTGAAGGGACAGGTCCCTCTTCCATG GCACACACTCTGTGTGTAACAGAGCACACGTGTGACCAAACTGACCTGGAGAAAGGGCCTGACCACATCCATATCCCAAGTTCTGAGGCCGGATAGT GCCTGCAGGGGCTGAGACCAGGGGAGAGGCTCAAGCCAGCCTTCTCTGGTGGACCCTGACTCAGTCCTCTGTGCAGGGCAGCTGCGCCTCCCAGAAG GCAGAGGCCTCTTGGAGAGTGAGCCTTGCGGTCACAGCGCCTTTCGGGGGCTCCCGCCACTTGCCCTCAGTGGCGGCTGAGACCTGGGGGAGTCCAG GCAAATCCCTGAGGAGGCCCCACATGCAAGGCCTGAAGTGTCTGGATGGTGTGGCCGGCACCCTTACCCTCCAGACCAGCAAACGAAGCCCAGGCAG GGAGAGGGGCCTTGTAGTTTTCTGTGGCTGCTGTAAGGAATTTTCACACACTCAGCAGCTTAAAACAACCAACATTTCTCTCATAGTTCCAGAGGCC AGCAGTGTCTGCAGTGCCCGCTCTCTCCCAGCTTCTGGTGGTTTCGGGCGACCTTCGGCTCTTCTCAGCTGGTCCATGTGCA HUMAN SEQUENCE—mRNA GCAGTTGCAGCGAGCAGCAGAGTCCGCACGCTCCGGCGAGGGGCAGAAGAGCGCGAGGGAGCGCGGGGCAGCAGAAGCGAGAGCCGAGCGCGGACCC AGCCAGGACCCACAGCCCTCCCCAGCTGCCCAGGAAGAGCCCCAGCCATGGAACACCAGCTCCTGTGCTGCGAAGTGGAAACCATCCGCCGCGCGTA CCCCGATGCCAACCTCCTCAACGACCGGGTGCTGCGGGCCATGCTGAAGGCGGAGGAGACCTGCGCGCCCTCGGTGTCCTACTTCAAATGTGTGCAG AAGGAGGTCCTGCCGTCCATGCGGAAGATCGTCGCCACCTGGATGCTGGAGGTCTGCGAGGAACAGAAGTGCGAGGAGGAGGTCTTCCCGCTGGCCA TGAACTACCTGGACCGCTTCCTGTCGCTGGAGCCCGTGAAAAAGAGCCGCCTGCAGCTGCTGGGGGCCACTTGCATGTTCGTGGCCTCTAAGATGAA GGAGACCATCCCCCTGACGGCCGAGAAGCTGTGCATCTACACCGACGGCTCCATCCGGCCCGAGGAGCTGCTGCAAATGGAGCTGCTCCTGGTGAAC AAGCTCAAGTGGAACCTTGGCCGCAATGACCCCGCACGATTTCATTGACACTTCCTCTCCAAAATGCCAGAGGCCGAGGAGAACAAACAGATCATCC GCAAACACGCGCAGACCTTCGTTGCCTCTTGTGCCACAGATGTGAAGTTCATTTCCAATCCGCCCTCCATGGTGGCAGCGGGGAGCGTGGTGGCCGC AGTGCAAGGCCTGAACCTGAGGAGCCCCAACAACTTCCTGTCCTACTACCGCCTCACACGCTTCCTCTCCAGAGTGATCAAGTGTGACCCAGACTGC CTCCGGGCCTGCCAGGAGCAGATCGAAGCCCTGCTGGAGTCAAGCCTGCGCCAGGCCCAGCAGAACATGGACCCCTGGGCCGCCGAGGAGGAGGAAG AGGAGGAGGAGGAGGTGGACCTGGCTTGCACACCCACCGACGTGCGGGACGTGGACATCTGAGGGGCCCAGGCAGGCGGGCGCCACCGCCACCCGCA GCGAGGGCGGAGCCGGCCCCAGGTGCTCCACATGACAGTCCCTCCTCTCCGGAGCATTTTGATACCAGAAGGGAAAGCTTCATTCTCCTTGTTGTTG GTTGTTTTTTTCCTTTGCTCTTTCCCCCTTCCATCTCTGACTTAAGCAAAAGAAAAAGATTACCCAAAAACTGTCTTTAAAAGAGAGAGAGAGAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA HUMAN SEQUENCE—CODING ATGGAACACCAGCTCCTGTGCTGCGAAGTGGAAACCATCCGCCGCGCGTACCCCGATGCCAACCTCCTCAACGACCGGGTGCTGCGGGCCATGCTGA AGGCGGAGGAGACCTGCGCGCCCTCGGTGTCCTACTTCAAATGTGTGCAGAAGGAGGTCCTGCCGTCCATGCGGAAGATCCTCGCCACCTGGATGCT GGAGGTCTGCGAGGAACAGAAGTGCGAGGAGGAGGTCTTCCCGCTGGCCATGAACTACCTGGACCGCTTCCTGTCGCTGGAGCCCGTGAAAAAGAGC CGCCTGCAGCTGCTGGGGCCACTTGCATGTTCGTGGCCTCTAAGATGAAGGAGACCATCCCCCCTGACGGCCGAGAAGCTGTGCATCTACACCGACG GCTCCATCCGGCCCGAGGAGCTGCTGCAAATGGAGCTGCTCCTGGTGAACAAGCTCAAGTGGAACCTGGCCGCAATGACCCCGCACGATTTCATTGA ACACTTCCTCTCCAAAATGCCAGAGGCGGAGGAGAACAAACAGATCATCCGCAAACACGCGCAGACCTTGAGGAGCCCAACAACTTCCTGTCCTACT TTCATTTCCAATCCGCCCTCCATGGTGGCAGCGGGGAGCGTGGTGGCCGCAGTGCATGGCCCTGTCCTGAGGGAGCCCTTCTTCCTGTCCTCCTACT ACCGCCTCACACGCTTCCTCTCCAGAGTGATCAAGTGTGACCCAGACTGCCTCCGGGCCTGCCAGGAGCAGATCGAAGCCCTGCTGGAGTCAAGCCT GCGCCAGGCCCAGCAGAACATGGACCCCAAGGCCGCCGAGGAGGAGGAAGAGGAGGAGGAGGAGGTGGACCTGGCTTGCACACCCACCGACGTGCGG GACGTGGACATCTGA

[0297] TABLE VI MOUSE NOMENCLATURE ICSGNM CCnd3 Celera mCG15576 HUMAN NOMENCLATURE HGNC CCNDG Celera TCG1668G MOUSE SEQUENCE—GENOMIC NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGCTTCTGCCTCCCGAGGGCTGGGAT AAAGGCGTATACTACCACATACATCCCAAAATACATATAAAAATTAATAGAGCTAGTTGAGAAGTCTCTCCTCTCGTGATAGTCTCTGATTTGGGGA TACACCTTTCTTCATATTTGTATCAACCTATTTGCTGCAGTGTAGGTGAGGCTAGCCCAGTGTGTAGATGAAGTCTAGCCCAGTGTGTAAAGTAAGA AGGCTAGCCTGGTGTGTAGGTGAAGGCTAGCCCTGTGTGTAGGTGATAGAATTGAACTTTTACTTGAAGAGTGAAAGTGATTTAAACAATGAGGAAG CGGTAATGCTTTACTCCTCACAGAAAGTCCAGAGGTAGCCTCAGGACTGGTTCAGTAGCTTAGCAGTGTCACTCAGGCGAGGGATTCATTCAGATAA TCCACTAGGCCCCTTTCTTCATTGCAGAGATGGCAGAGGTGGCCCCAGCATCATAGTAGAGTGGTTACGGGCATAGCTTTGTGGTAGCATTTTTCTG TGATCCCTTTGGTTGGGAAGCTGAGGCAAGAACATTGCCAGCCTAGGCTACATGGTGAGAATCTGGTCAGGCAGGGCACACAGCAGAGTCCTGTCTG AGAAGGGTCAAAACAAAACAAAAGCGCAGGGCATATAAAACAGACCTTGTTTGCTAGAGCGTTTGCCTAGTTGCCCACCCTGTAGGAAGCCCTGGGT TCCCTCCCTAGCAGCTCACGAGCTGAGCATAGTGCTACACACTATAGTCTTCCACCATTCCTGCACTGGGCAGGTAGAGGCAAGAAGATCAGGAGTT CCAGGCCCAATCAAGTTTAAGTCTAGCCTGAGGTCCATGATTCCCTGCCTCTAAGAGAGATTTGAGGTTATCCTCAACTGTACATCACATGAGAGGC TAGCTTGGGCTACGTGAGCCACTATCTGAAGAAAAAAAGAGCTAGGAAGATAGCTCAGTGAGATGGTTCAGCAAGTAAAAATGCATGGTGGACAAGC TTAAAAACCTCTGCTCCGGGGCTGGAGAGATGGCTCAGTGAGTAAGAGCACTGACTGUTCTTCCGAAGGTCCTGAGTTCAAATCCCAGCAACCACAT GGTGGCTCACAACCACCCGTAATGAGATCTGACGCCCTCTTCCACACAATAAATAAATCTTTACAAATAAACAAACAAACAAAAACCCCTCTGCTTG GTCCTGGATCCTACTGTGGAAGATGAGGGACACACCAGGAGGTTGTCCACAGGTGCAAACACACACATATGCACACCCAATGTAATTGGAACATTTC AAATATATCTGAGCATGGTGGTAAAGTGCCTTTAATCCCAGCACTCAGGAGGCAAAGGCGGGGCGATCTGTGTGAGTTTGAGGCTAGCCTGGTCTAC ATAGTGAGTTCCAGGACAGCCAGGGCTACACAGCAGTGAGGCCCTGTCTACAAATAAATAGACAGACAGATAAATAAATAAGCGATAAAGTATAACA GATCAGTTACACAGTAAGGCGTATAACAGATCCAGTAGTGTTACACAGTAAGGCCTGACTGATAGATAGACCGGCATACAGAATGATAAAATATAAT GGGGCTTGTAAGATGACACAGCAGGTAGAGGTGCTTGCTGCCAAGATCTTCAGAACCTATGTAATGAAAAAACAGAACTAACTCTCTCAAGTTGTCT GCTGACTTCTACGTACATATGCATGGCATACACACGCATGCGGAAACACATACACATTTAAAATGAAATAAACCAGTTATAATGGGGAGCTAGCTAT AGCTCAGTAGGTAGAGTGCCTGTGTAACCTGTAGGATACCCTGGGTTCAGTCCACAGCATTGTATAAACTGGTCAAAAGATGATCATGGTTGTAATC CTCGAATTCAGGAGATGGAGTTAAAGAGAAGTTGGATGCCGTCTTCATCTACAAAGTGAGTAAGAGGCTAGCCTGGGCTGCATGAGACCTTATCTGA AATATAGTAATGGATATTGCTATCTCAGTTTTGCAGTAGGCACAAGGTTGTATATTCUTGCCGTCTCAGAGCCTCAGAGACAGAAACAGGATGGACA TAAGTTTAGACCAGACGTATTCACTGTGAATTCTAGGCCAGGTAGACCTAGCAAGAGTTGCCTTAGAAACATCAACAAAACAGCAGCAGCAGCTTTT CATGAAACAGATTCCAGTCTGATGTACACACACATATCAAACCGAGCGGCTATTTGTTCAATTCTTTTTTGTTGTTGTTGTTGTTGTTGTTTGTTTT TTGTTTTTTTGAGACAGGGTTTCTCTGTGTAGCCCTGGCTGACCTGGAACACACTTTGTAGACCAGGTAGGCCTCGAACTCAGAAATCCACCTGCCT CTGCCTCCCAAGTGCTGGGATTAAAGGCGTGCACCACCACGCCCGGCTCTATTTGTTCAATTCTTGAGCATGAGGCTAGCTCTATCAGGAGAGTTCT GACCTAGAGGGGCATGGGACTTGTCATTTCAGAGTGTGGCAGCCTCCTTCTGAGTACCAGGTACCTGGATTGCTTAGTGGCTTGTTCTATCGGAAGC TATTGTACCTGCCCACAGCAAGGTGGAAGTGTCTAAGAACTGAACCGATCCTGAGTCTGCCTACAGAAGCCTTCAACCAATGGCAGCTGAGAATGTG GAGACAAACATCTTGCCTCATTGTGCCTCAGCTACAATCATGATACAGACAGTTGTAAGCTGCCATGTGGTTGTGGGAATCGAACCTGGGTCCTCTG GAAGAGTAGTCAGTGCTCTTAACTGCTGAGCCATCTCTCGAGCCCTTGCCCAGCCTTTTTTCTTAAAATTGTATTTTTAAAATTTATTTTCTGTACA CAGGTGTGTGAGTGTGAACATGTGGATCCTAGGGGTTGAAATCAATTTGCCGGGGTTTGTATGGTGCCTTCTCACCAGCTTTAGAGTTTCTTGATTA CTAGCGAAACCTTCCTGGAAGCAGGATGCTACTCAGTATTTTGATCACTCATAAGACATTTCATTGTGAAGTGGAAAGAAAACCTTCGTATGTTGTT TTGTCTTGTTTGTTTAATATTATATTCTACAGAACATTATATACAGATGTCATAAGGACAATAAGGACATAGTTTATTATTTATTTACTTATTTTTG AGAAAGGGTCTCACTAAGTAGCCCTGCCTGGCCTGGAACTCACTATGTAGTCTAGGTTGGACTTGAACTCACAGAGAGCCACCCACCTCTGCTTCTG GAATGCAGGGACTAAAGCCATGAGCTACCATGCCTAGCCAGATTGTAGTTTTGTTTGTTTTTGTTTTGTTTTTCAAGACAGGGTTTCTCTGGGTAGC TTTGGCTACCCTAGAACTCACTCTGTAGCCCAGGCTAGCCCCAAACTCACAGAGGTCCATCCATCTCTGCCTCCTGAGTGCTGGGATTAAAGGCATG CATCATCACACCAGCTGAGTCTTTTTTTGTTAGGAAAATCTCCAAGTTGTCTATCCTTGAGCTTTGTGGTATTCTTTTCCTGAGACTGGGTCTCATG TAGCCCAGGCTGGCTTCAAACTCAGCGGATAGCTGAAGATGCTCTTGAGCTTAAAACTCAGCTTCTTTATTTTCTTTATTTACTTACTTTTATTTTG AGGCAGAGTTTCTCTGGTGTAGCCCTGGCTGACCTAGCACTCTATTTGTAGCCCAGGCTGGCCTTGATCTCACAGAGATCTGCCTGCCTCTGTCTCC TGAGTGCTGGGCTGAAAGGTGTGTACTGTTGCACCAGGCTAGCGGCTTTTTTTTTTAAAAAAAAGATTTATTTTATTTATGTATATGAGCACATTGT TGCTCACACACCAGAAGAGGGCATCAGATCCAGTTATAGTCTGCTGTGAGCCACCATGTGGTTGCTGGGAATTGAACTCATGACCTCTAGAAGAGCA GACAGTGCTCTTAACCATTGAGCCATCTCTCTTCAGCATGGCCTTTTTTTCTTTTCCTCTTTCTTTTTCTTTTCTTTTCTTTTCTTTTCTTTTTCTT TTTCTTTTTCTTTTCTTTTTAAAGGCTTAATAACTATTCTTTTTTTTCTTTTCTTTTGGAGACAAGGTCTCATTTTTAGCTTAAGTTGGCCAGGAAT TCACTCCATAGCCTAGGCTGACCTTGAACTTGGGGAGATTCTCAAATTGGGATTCCAGGTCTGTGCTACCAGGCCCAGCTTATACAATTGTGTTTAT TTCTCAATTTAAAAAAAATCCATTTTTATTTTATGCGCTGGGGTATTTTGCCTGCATGTATTTATGTGTACACGCATGCCTGGTGCCTGCGGAGGCC AGAATGAGCCTCAGAGCCCCTAGAAATAAAGTTACAAATAGCTGCACAGGTGCTGGGAAGTGAACCTGGGGCCTCTGCAGATAGCAGCAACTGCTTT TAATCGCAGAACACTCTTTCTAGCCTTTAATTTCTCAATTGAGGTAAATGTTATTAAAAGTTATAAAAATGGGCCATAAAGGGTATGTGTTCTTGGC ATACAAGAAGCCCAGGGTTCAGCCTCAGCCACTATTATTATGTTGATAGTTGTAAATACCCATACACGAGGACAAATTTGGCTTTTACAAAGCCAAG CATAATCAGTTGGACAGTGGTGGCGCATGCCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGGCAGATTTTTGAGTTCGAGGCCAGCCTTGGTCTAC AGAGTGAGTTCCAGGAAAGCCACGGACTACACAGAGAAACCCTGTCTCAAGAACAAACAAACAAACATCCATAATCACAACTCAACTACCTGGCACC CACCCCCCTGCATCCCTGCCTCCCCTGCCCCTCCACACACACACTGTGGCTCTGGGGATTGAACCTAGGGACTAAATGAATTCCGAATAAGTGCTTT CCCAGTGAGCTTACCTCCAGCTCAGAGAAGAGTGTGTGAGAGAGTGGAGAGGGTAATTGTTAGTATATAAGTAACCTTTTTGCTTTTGCTTTTTTTT TTTTTTTTTTTGAGGCCGAATCTCACTATTCAGTAGTCCAGGCTGTCCTTGAACCTGCAGTTCCTCCTGCCTCAGGAGGATGAATGAATTACGATTA CAGGTGTGGGCTACCACAATTGGTTTAGAAACTACCACATTTGCATGTTCCCTTTGCCCCGGATACCGTGCAAGATACTTTAGGCCCTTTGGTCATC AAAACATCCCGGTAGGGTACGGACTTTGTTATTACCCATCTGGATGATGATAAAACAGACACGAGAGAACCAGTAGGTTCTCAAATCACTCCAGGAG TGGCCTCATTCCGGTGTTGTGTCCACCTTCCTATTTAGGGGTGGTATCTCCTCATCTTTTCCCCTACCTGGTTTCTTCTCTCTCTCTCTCTCTCTCT CTCTCTCTCTCTCTCTCTCTCTCTCTCTCACACCTCACACACACACACACACACACACACACACACACACACACACACACAGTGGGTCTGAGAGTTA GGGTGAGGTGAAGGCCCTCACCTGTCACTCTGTTCCCCTTCTGGGTCTCAGTTGGAGAGATTCCTTGATATAAGAGGTGAGGGAGTGGTAGGAGGAA GGACCGCTCAGAGTCCTTCATCCTCTGGCCTTTCCTTAGGGCTTGTGACAATTACATTCCAGCTGTCCTCTAATTTACCATTTCATTGAGTAACTTG TAATTGGATGCACCTGGCTTGAAGCACTTTGATTTATTCCCCCTGGTTATGGGGCTAGTGTGAGCTGTCTGGCTCTTCTTTCCCTGTCTCTTTGTCT CTCTCCTCCTCCACTCCCCTCTCCTCCTCCTCCUCCTCCTCCTCCTCCTTCTTCTTCTTTCTTATTCTCTCTTCTCTCTCTCTCTCTCTCTCTCTCT CCCACCGCTCTTGCTTGTTTGTTTGTTTTTTGGTAGTTGTTTGTTTTGTTGTTGTTGTTTTGTTTTTGAGGCAGTCTCACCTAGCCCAGGCTGGCCC TGAATGGCTGCCCACCTTGCTTCCACCTTCTAAGTGTTGAGATTCCCAGTGTGTGTGTGACTCCTCCAAGTTTTGCCCAGTTTTTTATGCAGTGCTG GGATTGAACTTAGAGCTTCTTGCATCTTAGCCTAACACTACCAACTGAGCCTCATTCTCAGCCCCTTTTTTTGTTGCTTTGTTCTGTTCTTCGAAGG GCAGTGATGGTGAAGCCGGATAAGCAGACCTCTCTGGAGTTCTCCCGGGGAGGCCTCCTGCTCCCCCAGCAACCACCCTTCATGTAGCTGGCCAGCT CCTTGGCCCTGAAGGCCCAGGACAGTGGGGCTGTTGACCAGTTATCCAAGAAACCTTCTAGGACTCAACTGTCTCTCTCTCTGGGTGCCCTTTCTCA GTAGGTCAATGAGGAATAGATCATATACATCCTTGGGACAGCACAAGAGGCAATGGAATGAAGTGGTCAAGAGTTGGTAGTTGACTGCTGCTTTCAG ATCTCTGTGGCTCAGCACCGCCCCTGCGCCTTTGAGTTCTAACTCAGTGTGCTTAATTTTTTGTTTCCTTCATTCTGTCTTCCAAATTCTTGAGCAT GTTTGCCCCGGCACTCTGGGATTTCACCCTGTTTGTTATTCTGAAGACACTCTCATCCTTTTCTATTCCCATCGGTGCATTTTTCCATTTATCGGTG TTAGATTGTGAATGTCAGCTCAGAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTTTCTTTATATAAGGATGATGACGTAATCACAGGTAAAGAT AGGAGCTGAACCAGTGGATTCTGGGAATATGGTGGCTGTTGTCTTGGCAACAGGTGTTTGGGGTCCTGCCTATGTGATGTCACGGTTTTTTGGAGGT CCTGATACCAACAGTCTCTCTCTCTCTCTCTCTCTCTCTGTCTCTCTCCCCCCGCCTCTTTCCGCCACCACCTTGCCACTCTCTCTCCTAATAAACC TCAGGTGGAACTGTTTGGCCTGGTGCAGTCCTTCTGAAGCTGACATTCACCAAACAGTTGGCAACAGGAGGTCCTGATACTAACACAAAAGGCAAGG CTTTCTCTCCTCCTCAGTTCATCTCTCTTCCTGGAAGCTTTCTTCCCTGTTTGTTTGTTTGTTTCCCAAACTCTAATAAAATGGTCTTCAAGCTTAT TAAAACAAAAAGAAGCCATGGGGGTTAGAAAGGTAGCTCAATCGTAGAGCGTACCTACCTAATATGACCAGCATCGATTTCTCCTGATGTCCACCCA TTGCAAGGGCATCAACTCTGGAGCTAAACCAGACTGCAGCCTGCTTTTACCAACTCCGAGCTATGTGACCTCTCCGTGGTCACTTGCCATCCATGGT GAGTATTAGCACCCAGCCCCTATTACACAGGGCAAAAATAATATACTTTCTGTAAGGCTGTTGTGAAGATAAAATGATTTATTACCTCTCAGATATG TTCAGTTCTTGGACATGGTATGTGTACATGAAGACCTGTTACTGTTGTTGGTACTCACAGCCAGTTGTTGTGTCCAGAGGATACACAGCTACGCGGG ACTTTATCTCTGCCCTTCAGGACAGGAAGTTTGGTGGTGCATTCCTGTAATCTCAATATTTGAGAGGAAGAGGCAGTAGGATTGTTGCAAGCTGGGG GCTATTCTGGTCTACCTAGAGTCAGAGCTACATAGAGTCAGGTCTATAAATGTCAGAGCTACATAGTGAGAACCCGTGTCATAAAACTAACAGAATG TTAGTGTGGGTAAGGCATGCAATTGGGAGGTAAAGCAGGAAGATCAGATCCAGCCTCAGTTATATACTAAATTTCAAAGCTAGCCTGGGTGCCGTAA GACCCTTGTCTCAAAAAGTGTCCCCTCCCTCATTCGTTAAGTGTAAAGCTTGATGTATAAACATGGTGGTACGAATTTGTAATCCCAGCACTTGGGA AACTGAGGCACGAAGCTGGAGAATTCGAGGTCAGCTATAAAATAAGACAAACTGTTTCAACGAGGAGAGAAACCACTGGGGCAGTGACCTTCTGTGA CTGAAGCAATCCCATCATGCCTCCTTCCTGTATGAAAAGCCATCCCCATATGTGGATTCTGACCCCTTGCTCAGCGCAAGACTAGTGTGTAGACCAG TGTGTAGACTAGTGTGTAGACCAGTGCATAGTCCAGTGTGTAGACTAGTGTGTAGATGGATCTCACTGCTTATATATTGTCCTGTGCTTTCCTGGGG CTCACTTGGGCTGAGCAGAGAGAGCAGTGTCTTAGTGGTGGGCTTTCTTCTTTCTTTCCCTCCTTTCCTCTTTCCTGCCTTCCTTATTACATCCTTT TTTCCCTTGATTTTTGTTTTTGAGACATAGTCTCATGATATTAGCTCCTCCTGACCTAGAACTCTTATTTAGACTAGGCTGGCTTTGAACTCAAAGA AATCTGCTTGCCTCTGTCTCAAAGTGCTGGGATTAAAGGGGTGCTCTGTCATGCCTGTCTTCCTTCCTTCCTTCCTTCCTTTCCTTCCTTCCTTCCT CTTATATAGCCCAGGCTGCTCCTGAACTCATTAGGAAGCAGACAGTGACCTTAATCTTCTGATCGTTTCTGGGTTCTGCAGTGCTGGGGATTGAGCC CTGGGCTCTGAGCATGCTAAGCAAGAGCTCTTCCACCTGAGATATTTCTGCAGCCCACCCCCTGCCACCGTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGGAGAGAGAGAGAGAGAGAGAGAGAGAGACTCTAGGCAGGCCTTGAATTGTCTGTATAGTGGATAGTGGATCCTG GTGTTAAGCCAACACTTCCCTGGGTCTGAGATTACTGGCTTGCTCCACCACAGCCAGCACCAAATGGCTTTTTATATGCTGATTTTCACCAACACTG CTCACACCTCCGTTGGTGCAACGCAGTGTCCCATTCAGCAGACCTTGAGAAACTGCATTTCTTCTTTTGCTTTTATTTTCGTTGTGTATGTGCATGA AGGTGTGTGCGCACATGCTACATACAGCCTTGGTGTAGAAGTCAGAGGACAGCTTATGGGAGTTGCTCTCTTCTCTTCCATCATGTGGGTCCCAGGG ATCACACTCAGGTTGCCAGACTTGATGCCAGGATAGTTTACCCTCTGAGCCATTGAATCGGACAGAAACTACATGCTCCCACATGCTGCTGCAGATC TGCGCAATTCGTTAAAGTAGACGAGATTCTAAGTCAAGTTTCCCGACGGACCAACAATGAGATCTTTGCAGCTACTATTGTGCCTCAGTATCATGGT CTGCAAAATAAAGCCCAACTCGAGGCCATTCCTAGAAGCCACTTTAGGGTAGGAGTGACCCAACTATGTACAAAGTTATGACCACATTCCCTAGAGC AATGAAATATGACGTATACACGAAGGAATAACTTTTGGCGCCTAGTTCTTTCCTGGGTGGCTAGAATCGCGACGCGGCCCAGTGATGGGGAAGAGGG CACCCTTCCAGAAAGTTCTCTCTACCCTCTTGGTCAGAAGGGACCCGAGGGCCCGGAAGCGTGCGGGCCGGAGCCCAGCGGACCAATGGGGCTGCGG GGAGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNCCATCGCAGGATGGAGCTGCTGTGTTGCCAGGGCACCCGGCACGCGCCCCGGGCCGGGCCCGACCGCGGCTGCTTGGGGACCAGCGT GTCCTGCAGAGTTTACTCCGCCTGGAGGAGCGCTACGTGCCGCGAGCCTCCTACTTCCAGTGCGTGCAAAAGGAGATCAAGCCGCACATGCGGAAGA TGCTGGCATACTGGATGCTGGAGGTAAGGCCCGAACGGGTCCCCTCTCCTCACCCCACCCCCACCCCCGGCTCTGGGACAAATTGAACTTTCCCTGT CGGATCTTTGCGATCCCGACCACAATCTGCAAGATGCTTTGGCGGCCCAGACTACTGGGGCCTGGCCTTTTCACACAGGCGCCCTAAGCAGCTGCCT GCGTTCTGTCCCTTTCCTTTCCCCAATCCTGATCGGCTTCTTCTGTGATTTCCAGTCACTTGGCACTGTAACTAAACTTCACTTTGGGTCGGGAAAG CGGGCTAAGGGCCACTCTTTCCCCAGTGGCTTTCCTCGGTGTCTCCTGCTTCCTTCTTCACCCGGTGCTCTCTGGAGGGCGCGTTTGGAAAACCCTG GCCTCGGCCGCCTTAGCCCCAGAACTGGTTCCTGTGTCTATCCCGGGGTTCTGGCGGGGGAAACTGGTGGGTGGGGGTGGCGCAGGCTCGGTTCCGG TCCACAGGGAATGAAAAGTGCGGGAGACCGCGGCAGGAGTTCCCTCCCTTCCCCCTTGGGAGTGTGTGTGCAGTGGGTGGCGGTAATGAGGGTAAGG TCCCAATTCTCTCTAGGTGACCCTTCCGTCCCCCTTCCGCTCGCCGTGGGGGAGGGGAGTCTGGAATCCTTCGTGAGCATGGGCTTCTCTTTTACAC CCCCTACTCCGGGGTGGGGAAGAGACCATGCAGAGGAAGTGGGGGGGTCACCTTGGGGAGGGCACATCCTCCTCGGTTATTGATACTTGTCGCTCTA AGTTTATCCCTTCTCGGTTTATTTTTTGCTTCGCATTCCACTCTCCCTCCACCCCCCACCCCCACTTCTCCACGCTGCCGTGTTTCACTTGGTCCTT CCCTAGCAATGACTCGTGCGCCCTCCCTCAGGTGTGTGAGGAGCAGCGCTGCGAGGAGGATGTCTTCCCTCTGGCTATGAACTACCTGGATCGCTAC CTGTCCTGCGTCCCCACCCGAAAGGCGCAATTGCAGCTTCTAGGTACCGTCTGCCTGTTGCTGGCCTCCAAGCTCCGCGAAACCACGCCCCTGACTA TTGAGAAGCTTTGCATCTATACGGACCAGGCTGTGGCTCCATGGCAGTTCCGGGTGCGTGCGGAAATCCTCCCCCCCCCCCGCCCCTCCACCAAACA TACGATCGCCCTATGTACTAGTAAAAAGAAAAGCCAAGCTCACTCCCTGACCCACTCCCTCCCCTTCGCCCCCCTGGCTGGTATTTTGGGACTGGCC TTGTAGTGTGGTCGTCGTGCTTCGGTGCAAGCTTAAAACTAAATGAATCCCTTTCCTCTGGCCGCAGTGGGGTTCCACTCCTAACTTCGCCCCCCCC CCCCAATAGCAACAAGTCCAATTGCGGGTCTATACACCAGTACTTTGCCTCTGGGTTTACACAGCCACCGTGAGTTATTTATTGGCAGCAGCAGGGC ATGTCTGCACACCCCCACCGGAGTGGAATGTGCTTCCGTGGGGGGAGGGGGCTGCCTTGCATGAGCCTTTATCCCCGTGTGGACTTTGTGATGGAAA AGCCTCCCGGAGCTGATTAAAGCCAGGCCCTGCTCGCTGGAAGGAAGCGCTGAGGTGTTTTCATCCCTTTCCCTCCTATCCCCGAAGACACCGCTCT TTTCTAAACCCTCCCTTTCTTGTCTTCCTTCTGAAAAACTCGAGCAGCTGCTCTGGGCCCGTGGAAGAGTTTCTCCCTTTTGCTGCTCAGCTAAGGC CAGAGCCGAGACAGACAGGGAGCTGAGCTGCAGCTGCTTCCGATGTGATAATGATGCCGGGGTCCCCTGGCCCCCTCCTCTCAGACTGGGCTTCATA ACCCTGTGGGGGCTGCTGTCACTCCTGTGGTTTGGGAAGTGGCTCCTTGGGGCCTCTTGCTGGGAACTTGGGCTGGGCTCCTCCAGGCGGGGCAAAA AAAAAAAAAAAAAAAAAAAAAAAAAATCGGTTGGGTTCTGCCCTGCCCCGGAGGAGTCTAGGGAGGAGGTGGATCTGCTTGGATCTGGAAGGGAGCT TGAACGTCATCTCCCACAGGGTCTGGGGGAGAGGGTGGGTGAGCTGGCACCTCCCTCCACCTTGTTCTGTGGCTGGCCAAGCCTTCTCTGACCCTGA GAGGAGTCTCTGGGCCCCATCTCCTAGGGAGGAGGGCAGCAGGCAGACTCCTGTGATTGGCTGGCTGGGAAGCTAGGGTACTGGGGCCCCTGACTGC TGTGAGTCGGGGGAACTGGATTCCTCTTCTGTCAAGCAGCTCTCACGGAGGATGGGACCTGAGTTGGAATCCGGGAGGCCCCACAGCTCTTTGTGAT GAATCTAGTTTCCAGAGCCAGGGAGCACGATGTTTTTTGAGGGATTGAGGCTGGGAGGTAGGAGACTTACTCTTTGTGAAGAGTTAAGGGTGGTCTA CATGGCTGTGTGTGAGGGGAGTTTTTTCAGAATAGGCAAAGCCCTCCTTCTCCTGCTCGAGGCCCTGAGCTGAGAGTTCCTGCGGTCAGAGTTGTGA GGGACTCCAAGAACTCCAGCAGTCTAAATCCACACAGCAGAGCAGAGGCCCCAGAAAGGAGGGGAAAATCCGACCAGAGCGCCTTGAAGGGCAGGAT GGGTTGCTGCTGCCAGCTCCTCTGATCTTGGGGTAGGGCTGGGGTTTTTCATGTCATCTGGATACAGGGGAGCGTGCCCACCTAGTGAGGACTCCCA CACTCCTGGTTGCCATTGGGGTGCCCCTTTAGAGGCTGGATGCTATTTGGTTATTAGGATAGAGCCCAGGGTGCAAGCTTCAAGCTTCCTTGCCTTA CTTCTGGCTCTAGTCCAGGCTGTTTCTGTGGGGTTCTGTAAGAAGCCTGGGGCTGACACCTAGGTCATGGGACAAAGAAGAGGGACAGCTGTCACTG GGGGGGTCCTGGAAGATACTGGGTGGGGCTGACATTTCTACCTCAGTGAGGAGTCAAACCCATGAGTTCCTTCCTGAGATAAAACAATGAAGAAATC CTCCTGTGTGCAACTCGGAAGTGCAGCTCGGGCCAGGGCTAGGAACTTCATATGAGTAGACTGAGGTTGGGGCTCCTAGCCTCCTCCTAAGACCTCT GAATGGTTATGTAGGCTTGGACAGGTTTCTCAGGGGTCATCTGGATTCATCCTGTTTGGCTTGGATGCCCTTGTCTGGAGACAGGACCCACCCGTGA TGTCCCACAAAGGGGGGTGTGGGTTGGGTTGGGCAACCTCCTCTTTGAGGAACCTTAGGAGTGGCTTCATGCTCATTTTGTTTAAGAGACCTGGATG CGATGTTGGGGAAGAAGAGATTTCCGAAGCCTGTGGAATTTAGAGTTGGTCTGTTTCAACTCACGCCCGCCTCAGACTCATGGGAGGATTAAGAGGG ATTAATTCAGGTCGTTCTAGCACCTAGTAACCATCAATAGATGCTTAAGTGTACGGCCCTAGTTCTTCCCTGCCCCAAACCCGTCATCCCGCGGCAG CAGCCCCTGAAGCCAGAGGCAGAACTGTGACCCTTCTGTCAAATTCTCGGCCCCCTCGGCCGACTGCTGACTCCATGTTCCTTCCCTAACCCCCAGG AGTGGGAGGTGCGGTCCTGGGAGCTCAAGTGGGACCTGGCTGCCGTGATTGCGCACGACTTCCTGGCCTTGATTCTGCACCGCCTTTGTCCTCTGCC CAGTGACCGGCAGGCTTTGGTCAAAAAGCATGCCCAGACCTTTTTGGCCCTCTGTGCTACAGGTAAGAGCCAACCTGGGGGAAATTGTGGGGTTTTT TGGGAAGGATACGTAGTAACAGCCAGGAGATGGTTTCAGTACTCAGACCTGTGTACAGTGATCTGGGAATACTGAATAAAAGTTACTTGCCTAAGGT CTTCATAGCAGGGTTTTGGATATTTTGTTGTTCCTGGTGCCAGGTACACCTTGGGTAGATGGAAAGTTTGTTGTTTGCTCATATCTCAGAGGAGGTC GGGCTGTGGTCTGGTGGGTCAGTGATAGGGTGCATTCCTCAGTCAGATTGCCAACACTGTGAGCACACACCAACCAAACCCCCTCCTCCCTAGGATC TACCTTGTCCCCTTGGCTCAGTGTCACCCCATTCACCACTGGGGGTTCCCAGGATGCAGCCTGGTGTGTTGTAAGATGGCTCCCTTTCTTTTCCCAG ATTACACCTTTGCGATGTATCCTCCATCCATGATCGCCACAGGCAGCATTGGGGCAGCCGTGCTAGGCCTAGGCGCCTGCTCTATGTCTGCGGATGA GCTCACAGAGTTGCTGGCCGGGATCACAGGCACTGAAGTGGTAAGTCTCAGCCCCTCGCCCCCCTTCACAAAATTAAAAAAAAAAAAAAAAAAGCTG TTCCTCTGAATCTCCAGCAGAGGGCACCATCCACCCGGGCCCCCAACTATGATTGTACGCCCTTGCCTGCTTCTCTGGCCTTTTTTCTCTGGCTCCA GTCTGGAGAGGAGTGGGTGGGGTGAAGGACACTTGGCATGTAGATACCCTTCTCTTGACATCTCTTGACAAGTGCTGTGTCTCGGACAGGGGTGGGG GACTTGGTGTCAGATGGAGGGTTGCTCTCACACCCTTGCCACATCCTCTTGCCAGTTTCTGAGAACTAAAGACCTGATTCCTGGGCTGGGCTGTGGC CTAACCTCCCCAGACTTCCCAGTGCACAGGGGGTGGCCTTTCCACCTGCTTGCTGTCAGTGCTGTGAGGGAGAGAGAGAGGCCCAAGGATGAATGAC CTTGTTTTTTTTTTTTTTTCTAGGACTGCCTGCGAGCCTGCCAGGAACAGATCGAAGCTGCCCTCAGGGAGAGCCTCAGGGAAGCTGCTCAGACAGC CCCCAGCCCAGTGCCCAAAGCCCCCCGGGGCTCTAGCAGCCAGGGGCCCAGTCAGACCAGCACTCCCACAGATGTCACAGCCATTCACCTGTAGCTT GAGACAGGCCCTCTCAGGCCACCAAGCAGAGGAGGGGCCCCTGCCACCCCCTCCCTGCCTCTAGAACAATCCATGCTATATCTGATGCCCGAGGGGG GCTCTCCTTCCCCCTCACAAAGCCCAAGGGGCCAGGTCCTGCCTATCCCCACAGTGTGCACTAAGGGGTTGCATGGTCATGAGGGGCGTCTTCATGG CCAGTCAGCTCCTCTTCCTTCCCACTCAACCAGCTTGGCTGTCCTGGGCCATGATGGTCAGAGAAATACAAACAGGTAAAATCCACAeACCAGCATT TCTTTTGAGTCCCTCTTCTGTCCGGGGCTCCAACCTTCTCAGTTGCCAAAACGCCCCAGTACCTTCCAAAGGTGTTGGCCCTTGCAGGCTCCTTCGG GCATCCCGATAGAAGCTTATGAGGAGCTGCCCTAGATGGCCTCTGTGTAATCCGTACTCCAGCTGCTCTTAGAGGGAACAGCCTAGGCTTTGGCCAG AGCAAGAACCCATACACTGTTGCTTTGCTTGCTGCTTAGCTTCTGTGATTGTGGGGTCTTAAGGGTGCCGTGGTCATTTTAATTTATTGCTTTGAAT ACAACTGTAAGAGGGTACAGTGAGGCCTGTACCCCACAAGTGGTGGTAACCCTGGCGGTTGCTCTTTCCCTCCCTTCTTCCCCTCTGCTACTGCTTT GTGGCCCAGGAGCTGCTACAGCCTGGGATGGGGGTCACGCCTTCCTCTCCTCACCCCTCCACCTCATCTTCATCAGAGCAGGGTTAGGTTGGGATGG ATCGATGCCGTGGAGGTGACAGAGCTATCTGGAGAGAGGGCAAGCCCTAGGGTCACAGGTCTTTCCTCGGGCCACAAGGTTTGGGCTGGTGGCCCAT TTCTATCATGCTGCCTTAATAAAGATTTCGGAATAAAGGTGGCTCTTGTGATCCCTGGGGTTGTGGGAGCTGGGGGGCACCAGGCAGCTGTCTTAGG CAGAGCACTTTTCCTGGGAAGGGTTAGAAAGGTGCCGCCTAGCCAGCATGGCCTGCTTTCCTTGTGGACGAATTACAGCGCTAAGGAGCAGCCAGCA TTACCCAGAGGGCTCATCGGGAGACAGGGCTGGACCCTTACACAGAACCCTAAGATTCATACGACATCAGGCATGGTGCTTCCTTAGCACACTCAGG GCAGACAGAGGAAGAGGGCTAGCCTGTGCTACATAGTGCAGAACTTTGGCTCAGCGACAGCACTGGCTACTCCTGAGAGCCTGGACTCAATTCCCAG CAGTTAACCATTTTAAACTCCAGTCTCAGGGATCTGATGCTGAGGCACAAAGCTCAGAATGTATTAAAAAAACAAAACCGGATGAATGGGGTTAGGG TGTGGCTGGAAGCACTTCCCCTAGCAGGGAGGCAGGCCCTTCCTCAGTGGTGCTGCAAAGGAGCAGCCCTGCATGGGAGAGGAGAGGAGAGGAAGAG CGAGGGAGGAAGGGAGGGAGAGCTTGAGTGAGCTCAGGGAGTAATTTGGTTGGGTTCGGCTAGGTTTGTTCTCTTTGCTTTGCCCTAATGTTTACAA GATGATCTACTGTGTAAGCAAATATGAACTCAACAGACCAAACCTTCTCAGATATACAAACTGGATTGTTATAGACACACGTTTTCAAAAGTGAACG TGATACAGCGAGGTGACTTCAGTCAGTCAGCTGTGATGCATGGTTCTAAGGGTTTTTGTTGTTGTTTTTIGGTGAGGTAGTGTTTCACAGCAGTGGC TCAAAAAGTTGAACCATCAGGCAGGTGGGTGGCCAAGTTCAAGGTCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGGCAGGGATACACAGGGAAAC CCTGTCTTAAAAAACCAAAACCAAAACCAAAACCAAACCAGACAGTATTCTTTGCTCATTAGTTATGCAGACACAGGAACCTGACCTGGCGTCTCAG CCAGCCTAAAGCTCTGGTTGCTTGATAGCTAGGAAGAAATCCCATTTTTCCTGATTCTGTTTGTGTCACTGTCCCCTAGCAAGGGCCTGCAATATAG TCTTCCCTGACAGTGAACCACTGCCACTTTTCCAACAGACACCTTTCCAACATGGCAGCAGAATCTGGCATCCCTAGAGTCGGCCCTGACTGTACGT CATGGTAGGAGTCAGGGGCGCGTGTGCATACATTTCCTGTGAGAACAGGAAGCAAGAGTTCTAGAGACACAACTTTGAAGAATAAGGTGGGGGGTGA GGTTTCTGTGGGAAGTTAGAACCCGCTCTTCTGAGCTGGGGACAGGGAGGAGCCAGCAGTGACTCCCACCTCTCCCGTGGGTGACAGGGGAGAGAGG CAGGGACCTCCAGGGACCAAAACACAAGAGCTGCGATAAATAAATGCCTGTTTTCTCCGCACCCCAGCGAGCTTTCACAGTATCTGGAGAGAGCAGA CCTTATACCAACTGCCAGGTGGGTTGTGGGGTCGCTGAACCGAACTGAGGTAACTCCGGTTAGCTTCCAGAAGTGAGCAGGGACCAAAGCCTAAAAT GGCAGAGAAAGCCAACCAGATGCAGTCCTCCCTGCCCAGGATTAGGCCACGGCAGCCATAGTAGCCCTTCAGTGTCTTGACCTAGGTCTTTAACTAT ACCAGCTGGGGTCCTGGGGTGGTCCTGCGCCCCCTGGGCCAACACAGGTGACTGTTCTCATTCCATGGTGACACCACCATCCTCCACGTCTCTGGGG ACAGCGCTCTGAAGCTCACGCCTGATCTCAGGGGACAGCTGCGGGTGGGCTGCAGCCGAAAGCAGCTCCAGGAGGGCCTCCTTCTGCTCTGTGGCCA TGTCAGCCTTATAGCGCTGCGCTAGTGTCAGCAGGCACTGGTGCCAGAGGACAGGCAGCTGGCGCTTTTCCGTCCGGAAGGCCAGAAAGTTGAAGAC CAGAGCGTCGAGCACGCGGTAGGGCAATGCGTACTTCTTATCCAGCAGCAGGCGCAGGAAGATGCTGTTGGCACCGCTGTATTCCATTTCTGCGATC TTCAGCATGGCCGCACTGGAAGGGAAGGTGGAGTCACAGGAATTAGGCCACACCTATGGGAGTCCTCTTCTTACACTGAGCCTTACTTCAGTGTTCC CAAGGGGGCCACCACAGGCTGCTCAGCTGTTGATTACTATGCTCCTGAGAGTTTCTACCATCTCCATCCATCTGCCCCACCCACACCTCTGCCTCTG GCTCGGAGAGCAAGCAATCCCTGTGTTTAACTACAGATCATGTCCAAATGTCTCACGATCCGCACATTTTAGCACACTTTCTTCCTAGATGCCCATT TACACACGCAGTCATTTCAATTATACTAGCTACCAGGACCCTGCCCCTGCTCTTGAAGACCTACTATTCTGTTTTGAGTTTCATACACCCACTGACA TAAACGGCTAGACTCGAGGTAATCATAGCTCATTCTCCATTCGCACCCTCACGACCAAGTTCCGGCCTCTCTATCACACGGCTCCTCTCTGACCATC CTCCTCCACCTCCCCACCACTACCTGGAGTGCAGCACGGGATGGAGCACTTGGTGATGATGCTGCCCACGATGGATGGCTTCACGGAGGGTACAGGT GCCGGACTCACACAGTGGGATCAGGATTCCTAGGCAGAGTCAGATGCAGTGGCTTTTAGACCGGGGTGAGGGTTGAGGCGCACCCCCCCCAGCAGCC CCAGGCATCAAGGACCCCCAATGATCTGCCAAGTAAGAGCCCCACCCCCTCCTTTCTCCCCTGCTTCTGCTCTACCTTTGAACCAGGCTCCAGGCTT GAACAGGGCCTTCTTGAGCGCCATGTAGAGGTGAAAGTTGAGTCGTTTGTATTCAGCAATGTCATCTCGCACTCGGGGAAGCAGGACAAGGTTGTAG AAGCGCTGAGCCATGCGCTCCTTTCAAGTTAGAGGCAAAATCCTAGCAGGGTAGGAGTTTCCAAGTTACCAGAGAGCCTGACCCTGGCCCTTTAAGA ATCATCGCGGATGGTGCATTCGAGAGGTTTTATAGTCAGACACGGGACAGCGTGTTTTTTATAGTCAGAGCTGTAGCATGGAGTGAAAGCTCTTCCC ACTGAAGAGTACCACAGGACTTGGTCATGAAACCTGGTTGGCTGGTGAGCTCAGTGGGTAGGAGCACCCGACTGCTTCTGAAGGTCAGGAGTTCAAA TCCCAGCAACCACATGTGGCTCACAACCATCTGTAACTGATCTGACGCCCTCTTCTGGAGTGTCTGTGACAGCTACAGTGTACTTACATATTAAAAA AAATAATAAATCTTTAAAAAAAAAAAAAGAAAAACGAAAGAGCAGGGGGCTGGAGAGATGGCTCAGCGGTTAAGAGCACGGCCTGCTGTTCCAGAGG CCTTGAGTTCAATCCCCAGCAACCAGACAGTGGCTCATAGACAATCTATAATGAGATCTGATGTCCTCTTCTTCCCGTAGGCATATATGTAGACAGA ATACTGTATAGATAATAAATAAATCCTAAAATAATAATAATAATAATAATAAAATAAAAACCAATAGACCTATAGTTTCCCCTCTAAAAACTAAAAG CCAAAACCATAAGACTGAAAGTGACTGAGTTCAAGGCCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTACACAGAGAAAACCCCTGTC TCAAAAAAAAACAACAATAACAACAACAACAAAAAAAAGACTGAAAGTGAGAATATGGAAAAATGACATACAAGAAAATGGAATCTAAAAGTCAAAC TTGAATATGCAGTCACACCTGAAAATAGGTTTAAAATCCCCAGAAAGAACAAAGTTAAGGGAGCAGCAGGAGCGCAGGAGCAAGGAGGCCATCGGGA ACTGAACAGCTCTCTGGCAGGCAAAGCCCCGCACCCCCCACAGCCCACAACCTGGCCCATCAATGATACTGGTGGCTGATACATGGCGCTGCAGTCC AGGCCTCAGGCTCAGTGACATAGAGGATCTGCTCCCAGTTGTACAGTGCAGGGGGATGACCTTAATGCCTTGTCAGTTTCCCACTGCGGTACTTACA TAACACCTGGGGTGAGAGAAGCAAATCGCCAACTGTGCTGGGGTCCTGGCCCCTGTTGCTCACTCATCTCCAGAACCATCTAGAAAGCCTCGTTCTC CGGGTGACCGGAGTTTAGTAGACTTCCAGGGTCTAAGAGACAGTGCAAGAACCTGAGCCTATCAGCTGTCCCCCCTTCCCCTGTTCTGATCGCCATG GCTTATTTGGTGGGGGGCCATGGATGAGAGCATAGGGAAGCCCGATACCTCTGACATGACAGTCTCCACCTCTGTCTGCTTCTCCGTAACTCTCCAT CTTCCAGGACAACCGGGATCCAGCTGAGGCATAGGGAGCCCGATACCTCTGATTGACAGTCTCTCCTCTGTCTGCTTCTCCGTCAAAACTTTCTCTT GATGATATCAGCCAGGGTGCGCCTATGGAGACACGGGAAAAGAGAGGTGGAAAGAATTGGGGTCACTTTCCATGAAACTGTAACGTCCCCCTCAACC TGTTTTTTATCTTTTTGTTGTTGTTATTTGAACAGGGGTTTTTATGTCTAGCTTTTGCCTGTCTTATCTGGCTCTGTAGAAACTTCTGACCTCAGAT CAGAGATCCACTTGTTTCTGCCTCCTTTGTGCTGGGATTAATGGTATGCCTGGCTCTGTTTATTAAAAAAGAAAGGCAGTAGTGGTGGTGTAAGCCT TTAATCCCAACACTTGGGAGGCAGGCAGATCTTTGTGAGTTGAAAGGTCAGCATGGTCTTCATAGGGAGATCTAGGCCAGACAGCAAGCCCCGTCTC AGAGGGGAAAAAAAAAGAAAAGTCACAAAACATCCCCCAAACAAACAGTTGCTTCACAAACTTGCATGTCCTCCTTGTTTTGCCACGTCCCTGTCAC TGTTCTAATTTTAGTGTACGGAAGCTGGAAGCGAGCAATGTATAATTCCCCTGGACGCTGACAAATCTCGATCCCCGCTGGGATGCACAGCCTCAGT TCCCCTCTATGTCCATTTAGCCGCCTCAAAGTGCTGCAGAGCACGGGCCTGGATGTCTCTGCATCTGACGCAGAGGCCAGAGTGGTGGGGACGTTAG GCCCTTAGGCCTGAAGTCAGCTCCGGCTCTTCTGGTCCTTGTATGATCCTGGGCCCGTCACTTGACTCCTCTAAGCCTCAGTTTTCCTCATCTGTAA ACTGGGCAAGTAAAAAGGACCCCCCCTGGACAGTCAGCTGAAGGGTAAAATTAAGACTGCAGCATCCCGACTCTCAGCCAGAGCCAGCAGGTCCTGA GGGCTGTTTACTTCAAGCTCACCTCCCACTGCTCACACAACGGGGAGCAACTTCTGAGTGCAGAGTGGAGCTCTGTGCCAGGCAGCGCTGGTGCACA CCTTTCATCCCAGCGCTCAGAAGGCAGCGGCAGGCAGAGTTTTGTGAGTTCAAGGCCAGCCTATCCTACTCACCCAGCACTTGCCTAGCAAGGATGA GACCTGGGTTCTGGCTTCCAGCACAAGGGGAAAAGTTTCTCTGCAGTCTTTTTTTCTGTGCCGAGCAGCACTGTTTCTGACACTTTTCTGACTTGTT CCTGTGGTCTGCATGACACTGGTGGCAGGTGCTTTTTATTCCCCCCGCACTGCCCAGGCCGGGAATCGAGACTCAGGGGCCAACCAACATCTCCTAA GCCCTAAGACTTTCTCAGGGAAAGGGTAAATTTTTTAGTCTTTCGACTTCTAGTTTTTGCTTCGCAGCGTCTTCTTGTGTCCCTTTGTGACAAGGCC TGATTGCTGTGTTCCCAAGACCCCTTAGCCTGGTTTCTGAAGATGCCAGTGCCACTGCTTTGAGTGCCCCACGGGTCCCCCCTTTCCACTTGTTGTC ACTTCCGTATAGCAACTGCAGAAACATCTTCTGCTAAGTTTGTCAGATCAGAGCCACTGTTATGAGGTGCTGCCCGAGAGCTTTTTGGGGGTCACAT CACACCCCATGACCATTCTCAGAGCTGTCAGACACCTTCAGGGGGACAGGTTCTCCTGTGTTCTCTGAACCCAAGCTGCTCATCACCGTACTATTAA TGATAGTGGTGTACTACACCCCACTCTGAAGAATAAACTGGTTGAGCCCCCTTTGCCCTAAGCCCAGTCCTCTCAAGAGGCCAGATCCATCTGAATG GAACCAAGAATCTGACCACAGGCAGCCTAAATAACTGCATGTTTAGAAGTAGCATTTATAACACATGGGGGTACGTTTTGGTTCCTACCCAGAGGTA GTTTTTAACCCCTCTGGGAACATTTTTGTCAGAGATAGCTGCTATTGGCCCCCACACTGTAACTGAGATGGTTCCCTGAGTTTAGACTAAAGCTATG GGCTGGCGAGATGGCTCAGCAGGTAAGAGCACTGACTGCTCTTCCGAAGATGCTGGGTTCAAATCCCAGCAGCCACATGGTGGCTCACACCCACCCG TAATGAGATTTGGTGCCCTCTTCTGGTGCGTCTGAAGCCAGCTACAGTGTACTTATGTATAGTTTTTCTAAATAATGGGCCAGAGCGAGTGGTTTGG CCAGAATGAGTAGAAGTCCTAAAATTCAATTCCCAACAACCATATGATGGCTCATAACCATTTGTACAGCTACAGTGTACTCACATACATAAATAAA TTAATCTTAAAAAAAAATAAGACTAAGCTATGAGAGTAACGTACCAAGAATAAACACTACTATCGAAGATCCCCAGCTATCACTGGTCCGGTTAATC CAGAGGTTCCAGATCAGATGGGCAAAGGGGAATCCGGGTCACTCCCGTTCAGGGGCCACTCTTGGCAATGGTCAGACCAACAGCTGTGGTCTGGATG AACTTTCTACCAGGACCCACTGGTCCAACCTTTAAGCCTTACCTCACGGGAGGATTCTTGTTCATGAACATTTCAATGGCACGCTCATCTTCAGGGT CCACGATCACCTCTGCCTGGTGGTCCACCCCGGCCATTTTTGGCTGCCTTCTCCAGGGTAGGCCACTCCTCATCCTCCTCATCTGATCCATCTGTGG CAATCCCGGCCCTACAAGATAATCCCAGCCGCAGGGGCTTGTGAGTCAGTTCCCCATTCCACGTACAGCACACCCAGGGAGCAGGAGGGACACCTGC AGAGGGACTATCCTTTTTGTCCCCAGAGACTTTGGAATCTTGATAGAAAATACAGCACACGAGCGAGAGATGATTAGGCCAGTTTGACTTATGGACA TGTCCCCTCAGTGAATGGATGACATGTCCCCCCTCAATGACCAAGAAGGATCCTTCTATACTACACACATGTTCCTGGTGCTGTCTGATGACCTTTC AAGGAATAGGTACTGTTGCTATACCAGTTCAAACCGGGGGCAGAAGAGTTGATGTGCCCAGAGTAGGTAGGCACTGTGGGTCCTGACTTCCCACTAT GTTGCTTGCACAGTGGAACTGCATCATGTGCTGAAAAACTAAAAACCATGGTGGAGGCAGTGTGCACCTTGGCACTTGGATGAGTACAGATCTGATA GGCTCTGGATGGGCAGTCTGGGAGCAAGAGCATGCTCCACGTCCTGGAAAGTAATGCTGTTAGAGTGTTGGGACTAAGGAGCCAGAAAAGGAAACGG AAAGCCAACCTGGAGGCTCTAGGCTGGGCAGTGGCATTTCGGACTCTGATCAACCAACACATTTTGTGTACTGGCTTAGGTAGTCTCGATATGACTT GGGAGTTCCTTGTTCTCGCGCCTCCACTTTCCAAACACGCACCACAGTGCTGAAGGCTGAGCTTCTGATGTTGGGTTAATCCCGTGTGTTCCATGTA AAGGCTGCCTGTGTACTATTCACATGTTAATCTTTGTTCCAGCAGAGAGCTGAGTACAGTCGGCATTGGTTTTTTTTTTYYYTTTTGCATCACCTGT CTCAGTGTTGTGGAAACTTCTTCTCCATCACCTTCTGATTGGTTTAATCAAAAAGCTGAGTGGCCCATAGCAGGGCTGGAAAGGATGGCGGGACTTC TGGGCAGAGATAGGACTCTGGGAAAAAGAAAATCAGATGTGAGGGGGAACTCAACCAGCCAGACACAGAGGTGTCACGTGCTGTTACTTGAGCAGTA ACGAGCCCCGTGGTTGAATGTAGACTAGTATAAAGCAATTATGTTGTATCAGCGAGTTCGGAACAAGGCAGCTAAGGCCAAGCTTTCATAACTAATA AGAGGTCTCTGTGTCCTCACTTGGGTGATAGGTGCGTTGAGCCATTCCTGCACATCCTGAGGTCCTGACCATGGAGTCTTCTGTGGCTGTTACTCTG AGTGCTGGGATTAAGTCATGTGCCAATACACCGGCTGACTTTTTGAATACCGCACATAGCTGGCAAGGCAGTTGGGAAAAGAGTCTAATAAAACCAA AGTAGTTGAATTATTACCATAGCAACAGATCAGTTGCTATGGAAGTGGACTAAGGGTATATTATATAGAGCTCCAGAGAGTACACAGAGATTACCCA GTGAGACCAAGGTTGTTTGTTTTAGGTTTTATTTTACTTTTAATGTTTGAGTGCTGACTGCACGTATGTCTGTGCACAAGTGTGCCTGGTGTCTAAT GACATCAGAAGATGGCATTTTGATCCCTTGCAAATGGAGTTACAGACAGCTATAGCCTGCCATATGAATGCCAGAACCAAACTTGGGTTTTCTGCAA GAACAAGTGTTCTGAAGAGCTGAGGACCAACTCTTGAGAGTTTTCCTCTGTTCTCTACACACATCATGCCACGTCATGTCACACAAAATACATGTTA ACAAAGGAAGACAAGAGCTATGAAATACGACGTAGGGAAGAGAGAAAAATCAGGAGACAGTCACTGACATTTGTGTGGTGTTTTTGTTTGTTGTGAT CATTTGCTTTTTGTATATGAGTGAACCCTGCATCATGGAAGTGACTCTTGGGAGCTGATGACCTTGTTTTTGAAACAGGATTTGACTGGGACCTGGG GATAGCTGATTAGGCTAGACGTTGCCCAGTAGGCCCAAGAGATCTGTCTTCTACACTGTAGCTCAGAAACTACAAGCTGCTGTGAGTGGTGAAGTCA GGGCTCATGCTCTCTCAAAGCATGGACCTCACCAGCTGTGAGCATTATCTTATCCTGTCCCTAGCTTGTGGTCAGACCTGAAACAGAGACAGACCAG ACAGGACGCCATCAATCTCTAGCTGCTGAAATGGACCACAGAGGTCCAGAATTCAAGCACGATGTTTCCACAGTGATCCAGGGGGAGAGACCCTGGT AGCTTAATCAGGGAGTGTCTCAGGTGAATGGAAGTGGTCTGGCTCTGAAATACTCTAAAGACAACATCACCAGGATTTACTTTGTGTGAGATGAAGA GGAAGCCTGGACTCTGACTGGAGCAGTGGAGCTAATGTGCTAACAACCTCCAAGTAGCAAACAGAGAGCAAGTTTGGGAAGGAAGTCACAACTTCTG TTTTAGATGCGATCTTCTTCTTTTATTTTTTTTTTTCCTTCTCCGAGACAGGGCTTCTCTAGGTAGCCTTGGCTGTCCTGGAACTTACTTTGTAGAC CAGGCTGTCCTTTGAACTCAGATTCCACCTGCCTCTGCCTTGTAGTGCTGGGATTAAAGGCGTGCGCCACCACTGCCCCTGCTTGGACGCAATCTTA CTAGAGTTAGATACTAGTATTCAACTTGGAGATGTCAGGTAGACCACTGGATATAAAGATGTGAGCTTTCTTGGACGAACTCTGAGGGAGAAAAAAC TGGAAGTAGCTGTCAAACAAATGGCCTCAAAGTGAAATTCCCTGAC MOUSE SEQUENCE—mRNA AGCGCCAGCGCCAGACCCGCCCGCACCCCGCGCTCTCCCTCACGCGCGTCGCTTCTCCTAGGACTCGCTAACCCGCACTCTTGCTCTCACCCGTGAG CCATCGCAGGATGGAGCTGCTGTGTTGCGAGGGCACCCGGCACGCGCCCCGGGCCGGGCCCGACCCGCGGCTGCTTGGGGACCAGCGTGTCCTGCAG AGTTTACTCCGCCTGGAGGAGCGCTACGTGCCGCGAGCCTCCTACTTCCAGTGCGTGCAAAAGGAGATCAAGCCGCACATGCGGAAGATGCTGGCAT ACTGGATGCTGGAGGTGTGTGAGGAGCAGCGCTGCGAGGAGGATGTCTTCCCTCTGGCTATGAACTACCTGGATCGCTACCTGTCCTGCGTCCCCAC CCGAAAGGCGCAATTGCAGCTTCTAGGTACCGTCTGCCTGTTGCTGGCCTCCAGCTGCGCGAAACCACGCCCCTGACTATTGAGAAGCTTTGCATC TATACGGACCAGGCTGTGGCTCCATGGCAGTTGCGGGAGTGGGAGGTGCTGGTCCTGGGAAGCTCAAGTGGGACCTGGCTGCCGTGATTGCGCACG ACTTCCTGGCCTTGATTCTGCACCGCCTGTCTCTGCCCAGTGACCGGCATCTTTTTTCAGCATGCCCAGACCCTTTTTTGGCCCCCTCTGTGCTAC AGATTACACCTTTTGCGATGTATCCTCCATGATCGCCACAGGCAGCATTGGGGGCAGCCGTGCTAGGCCCTAGGCGCCTGCTCTATGTCTGCGGAT GAGCTCACAGAGTTGCTGGCCCGGGATCACAGGCACTGAAGTGGACTGCCTGCGAGCCTGCCAGGAACAGATCGAAGCTGCCTCAGGAGAGCCTCA GGGAAGCTGCTCAGACAGCCCCCAGCCCAGTGCCAAAGCCCCCGGGGCTCTAGCAGCCAGGGGCCCAGTCAGACCAGCACTCCCCACAGATGTCAC AGCCATTCACCTGTAGCTTGAGACAGGCCCCTCTCAGGCCACCAAGCAGAGGAGGGCCCCTGCCACCCCTCCCTGCCTCTAGAACAATCCATGCTA TATCTGAAGCCCCGAGGGGGCTCTCCTTCCCCCTCACAAAGCCCAAGGGGCCAGGTCCTGCCATCCCCACAGTGTGCACTAAGGGGTTGCATGGTC ATGAGGGGCGTCTTCATGGCCAGTCAGTCCTCTTCCTTCCCACTCAACCAGCTTGGCTGTCCTGGGCCATGATGGTCAGAGAAATACAAACAGGTA AAATCCACACACCAGCATTTCTTTTGAGTCCCTCTTCTGTCCGGGGGCTCCAACCTTCTCAGTTGCAAACGCCCCAGTACCTTCCAAAGGTGTTGG CCCTTGCAGGCTCCTTCGGGCATCCCGATAGAAGCTTATAGGAGCTGCCCTAGATGGCCTCTGTGTTTCTCCGTACTCCAGCTGCTCTTAGAGTAA CAGCCTAGGCTTTGGCCAGAGCAGAAACCCATACACTGTTGCTTTGCTTGCTGCTTAGCTTCTGTGATTGTTGGTCTTTTGGGTGCCGTGGTCATT TTATTTATTGCTTTGAATACAACTGTAAAGAGGGTACAGTGAGGCCTGTACCCCATGTTTTTTTCCCCTGGCGGTTTGCTCTTTCCCTCCCTTTCT TCCCCTCTGCTACTGCTTTGTGGCCCAGGAGCTGCTACAGCCTGGGATGGGGGTCACGCCTTCCTCTCCTCACCCTCCACCTCATCTTCATCAGAG CAGGGTTAGGTTGGGATGGATCGATGCCGTGGAGGTGACAGAGCTATCTGGAGAGAGGGCAAGCCCTAGGTCACAGGTCTTTCCTCGGGCCACAAG GTTTGGGCTGGTGGCCCATTTCTATCATGCTGCCTTTTTGATTTCGGAATAAA MOUSE SEQUENCE—CODING ATGGAGCTGCTGTGTTGCGAGGGCACCCGGCACGCGCCCCCGGGCCGGGCCCGACCGCTCTGCTTTGGACTGCGTGTGTCCTGCATGTTTACTCC GCCTGGAGGAGCGCTACGTGCCGCGAGCCTCCTACTTCAGTGCGTGCAAAAGGAGATCAAGCGCACATGCGGAAGATGCTGGCATACTGGATGCT GGAGGTGTGTGAGGAGCAGCGCTGCGAGGAGGATGTCTTCCCTCTGGCTATGTCTACCTTATCGCTACCTGTCCTGCGTCCCCACCCGAAAGGCG CAATTGCAGCTTCTAGGTACCGTCTGCCTGTTGCTGGCCTCCAAGCTGCGCGTCCACGCCCCTGACTATTGAGAAGCTTTGCATCTATACGGACC AGGCTGTGGCTCCATGGCAGTTGCGGGAGTGGGAGGTGCTGGTCCTGGGGAAGCTCAAGTGGGACCTGGCTGCCGTGATTGCGCACGACTTCCTGGC CTTGATTCTGCACCGCCTGTCTCTGCCCAGTGACCTCAGGCTTTGGTCTNGCATGCCCAGACCTTTTTTGGCCCCTCTGTGCTACAGATTATACACC TTTGCGATGTATCCTCCATCCATGATCGCCACAGGCAGCATTGGGGCAGCCGTGCTAGGCCTAGGCGCCTGCTCTATGTCTGCGGATGAGCTCACAG AGTTGCTGGCCGGGATCACAGGCACTGAAGTGGACTGCCTGCGAGCCTGCCAGGAACAGATCGAAGCTGCCCTCAGGGAGAGCCTCAGGGAAGCTGC TCAGACAGCCCCCAGCCCAGTGCCCAAGCCCCCCCCGGGGGGCTCTAGCAGCCAGGTCCCAGTTGACCAGCACTCCCACAGATGTTCAGCCATTCAC CTGTAG HUMAN SEQUENCE—GENOMIC CACACCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCTGTCTCAGAAAATAAAAAAAATAAAAAATAAGTGGGATCTATTATTATTACTACCTA ATAGTATTATTACTATTATTGCTCTGGTGTGCTATCAGGGGTGTTGTGCCCACACTGTGACATACTACTCCTGACCCCCCTCCTTTCTTTTCTTTGG ATGCCCTCTTCTTCCTGCTTCTCTCTTCTTACTCCCACTTTTCTTTTTTTTTTTTTTTTTTTTGTGTGTGTGTGTGTTGTGTTGTGTCGCTCAGGCT GGAGTGCAGTGACATGATCTCAGCTCACTGCAAGCTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGC GCCTGCTACCATGCCCGGCTAATTTTTTGTATATTTAGTACACACGGGGTTTCACCATATTTCTGGTTGGTCTCGATCTCTTGACTTCGGATCT CCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCTGGCCTACTCCCACTTAATCTCTAAACTCCTGCAATCCCATTTCTT TCACCATGGCTCTTTCATGGAATTCAGGTGATCAGAACCACCAATCTCCACCAGTCCCAGGACAGCCCACCCTTCCTGTCACAAACCACCCTGCC TACTTCTGATGGGTGTTGCAAATGCCAGGTAAAGTCTTCTGTCTTCATGACATCTTAGGATTCCGCATCATGGAGGATCATCATATCATGCACT TTAGACTGGAAGCTTAAAAGGGTGGCTTCTCGGCCCAGCGCAGTGGCTCACGCCTGTTTCCCAGCACTTTTGAGGCCGAGGTGGGCTATCACGA GGTCAGGAGATCAAGACCATCCTGGCTAACACGGTGAAACCCCAACTCTACTAAAAATACAAAATTAGCTGGGCGTGGTGGGGGCGCCTGTAGT CCCAGCTACTCGGGAGGCTGTGGCAGGAGAATGGCGTGAACCTGGGAGGCGGAGCTTGCCGTGAGCTGAGATCGCGCCATGCACTCCAGCCTGGGT GACAGAGAGAGACTCCATCTCAAAAAAAAAAAAAGAAAAAAAAAAGGGAGTCTTCTCATCTCTGACCCATGTCCAGCATGTCCTGTTTCCGTG GCCTGCCTGATGTATGGAAGGCACATGATAAGGCACCTGATTGTTAATGACCACAGCTATCTTTATTGACCACCTACTATGAGCCTGGGACAGCTAA AGTACTTTTCCCTTATTAATCCCCTCATTCACCATATGAAATAGGAGTTGTTACCCATCCTCCTTTTGCAATGAGAAGGCTGGGACGGAAAAGTTAA GTAAACTGCCCAGGATCACACAATCACACAGCTGGCAAATAGCAGAGCTGGGCATCAACCTAAATCCAGAGCTCACTTACTTAATGACTAAGCCAAA CTAATGCCAGTGCTATCTCCTGCCTAGATGAGGATGCTTGCCAGCCAAGAACCGTGATGCTCTCTTTTTTGTGCAGGGTATATTGCTGTAGCAGGTT ACCCTTCCACACCTGAGGCCCTGTGTGCACCTCAGTCTTACCTGTGGAACAGGAATCTCAAGCAGAATGACAGAACAGGAAAGCCTCATTTATTCAG AACCCAGACAGCCAGAAAAAGGAAGAAAAAGCAAATGCTTAAATATATAGGTTGTATTCTTTTTTTTTTTTTTTTTTTTCTTGCTCTGTTGTCCATC TGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAAGCTTCCCGCGGGTTCACGCTTTCTCCTACCTCACCTCCCGAGTAGCTGGGAACTATGGCACCC GCCACCACACCTGGCTATTTTTTTTTTTTTTTGATATTTTTAGTAAAGACAGGGTTTCATCGTGTTAGCCAGGATGGTCTCAACCTCCTGACCTTGT GATCCGCCCCGCCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCTTGAGCCACCACACCCGGCCCTGTAGGTGTATTCTTATTTTTATTTAGAGACT TGACGTTTCAGGCTAGTACCTGAGGTTTCTTTTTCCCAAGCAGCTTATAAGCTAGAAATTGCAAACTGCTTTTTGTCCCTCAGACCTGGTATATAGG CATATTATGTGTGGCTTGCACGGTTTTGTTACTGTTTTTCAACTCAAGTAATATAGATATTTTTAGGAAATTTCTTTTTTTTGTTTTTGAGACGGAG TCTCGCTCTGTCGCCGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGCCTGGCGGAAATTTCTTTTCTTTTGAGACACAGTTTCATTCT GTCCCCCGGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCTGCCTCGTGGGTTAAAGCGATTTTTCTACCTCTGCCTCTTGAGTAGCT GGGATTACAGGCGTGCGTCACCATGCCTGGCTAATTTTTTTGTATTTTCAGTAGAGATGGGGTTCTCTATGTTTCTGGCTGGTCTTTAAACGCCTGG CCTCGCTGGTCTTGAACGACTGGCCTCAAGTGATCCACTCACCTCAGCCTCTTGTGCTGCGATTATGGCATGAGCCACCACACCACCCCAGCCTTTT TCTTTTCTTTTTGTAGTATGGGGTCTTGCTGTGCTGCCTAGGCTGGTCTTGAACCCCTGGCCTTGTGATCTCCCATCTTAGCCTCTTCAAATGTGCA GGGATTGCAGGCGTGAGCCATCATGCCCGATCTAAGAATATTATCTTGGGGAAACAGGGAATCTATGGCCACACTCATTACTATGGTGTAGCAAAAA GTCTGAAGCTAAGCAGTACTTTTTTGAGCTTTGGATGGGACATGTGCTATCTACTGTGTCTGGCCCCAACAGCTCCCTTAACCCATGTGAGTTGCCA TTTATCATGTGGTGTATGCTGGTGTTTTTCTTTTTTCTTTTTTTCTTTTTTTTTTTTTTGAGATGGAGTCTTTTCTGTAGTTTCCATCTGGAGTGCA GTGGCACGATCTCAGCTCACTGCAACCTCCGCTTCCCGGTCCCGGTTCAAGCAATTCTCTTGCCTTAGCCTACTGAGTAGCTTGGGATTACAGGCAC GCGCCACCATGCCCAGCTTTTTTTTTTTGTATTTTTTTACTAGAGACGGGGGTTTACCATGTTGGCCATCTGGTCTTGATCTCCTACCTAGTGATCT GCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTGGTGTTTTCTTATATCCAGTTTGTTTTTATTCATTAACT CAAAAAAAGATTTATTGAGCCAGACGTGGTAGTGCACGCCTATAGTCCCCAGCTACTTGGGAAGCTGAGGTGGGAAGACCACTTGAGCCTGGGATAG AGGCTGCAGTGAGTCGTTATCATGCCACTGCTTCCAGCCTGGGTGACAGAGTGAGACCCTGTCTCAAAAAAAAAACAAAAAAAACCAAAAAAACTTA CTGACATCTACTATGAACTGGATACCATCCTGTTTGGTGGTGTGGTGTGGGAGTAGACAAGCTGTAAACAGAATATGAACTGCAAAGCTATATGCTA TACTAGTGATCAGTGGTAAGCAGAAAAATAAAGCAGGGAAAGAGCATAAGAAGTGTCAGGGCTGGGGAGCTGGCATTAATTTATTAGGTAGGATGGC CAGGAAAGGCTGTAAGAGGAATGCAACTTTTGGACTTCCTGAAGGAGTGAGGGAGTGGGCCATGTGGATATCCGGAGGCAGTCATTCCACCAGGAGA TGGAACAGCACGTGCAAAGAGAACATGTCTGCCCGGTGTGTTCCATGAACCGTGTGGCCAGAGCAGAGTGAGGGAGAGTAGTGGGAAATGGGGTGGG AGTATAGATGCTGCAGGGTCTTTGGCAGTCACTCCAAATGAAATGGGGAGCCTCTGAGAGTGATGGGTTGAGACTAGACTGGAGGGCCAAGGGTGGG TCAGGGAGACCCCGGCAGGAGGCTACCACTGTAATCCAGGTAAGAGATGATGCAACTGGGACCGGGGGGTAGAAGTGGAATCGAGAAAAAGAAGGGA TTGGAGATGTATTTTTGACGTAGAATCAACCAGAAGTGGGTCGCAGGTTGGATGTGGGGACCAGTAAGGTCAAGGAAGAACTGAGTTTTGGACAGAG GAAGTAACAGAGGAGGAAAAAAAGAGTAGATTTTGGAAATATTTTGAAATTATTTTAGCTCCTCTGTGATCTGCTGATCAGAGTGTTAGTAATTGTG TGGGATTTGAGAAAGAGGAGTCAGGAATGACACCAAGTGTTTGGCCTGAGCCATTGGAAGGATGGAGTTGCCATTTTCTGAGATAAGCCTGTAGGAA GAGCGGGGTTTTTTGGGGGAAAGATTAGGGATATCAGTTTTGGAGAAGTTGAGTTTAACTGGCCTATCGGACATCCTTGTGTTGCCAAGAAGGCAGC ATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTTAGGCTGGTCTCGATCTCCTGACCTCGTGATCTGCCCGCCTCGGCCTCCTGTGCTGGCCCAAT TACAGGTGTGAGCCACTGCACCCAGCCAATTTTTGTATTTTTAGTAAGATGGGGTTTGCCATGTTGGCCAGGCTGGTCTTGTCTCCTGACAACTTCA GGTGATCCGCCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCCCCAGCCGAAGAGTGCTCAATTTTTACTGATAGGAATGG ACAAGCAAAGAGTTTTAAAGATTAATGTGAAATATTGTACAAATATTACAGATGCTCATAATAGTGACCTGGATACTGTAAAGCACCAGGATAGCTC CTTGATTCTCAAAGAAAAAAGCTAAATTATATGTAGTTGGGTTTACTGCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGGTCTCTGTTGC CCAGGTGGAGTGCAGTAGTGCGATCTGGGCTCACTGCAATCTCCATCTCCCAGGCTCATTTCTCCTGCCTTGCCTCCTGAGTAGCTTGGGAC TACAGGCGTGCGCCACTGCGTTCGGCTAATTTTTTTATATTTTTTGGTAGAGATGGGGGGTTTTTACTGTGTTGGCCAGGCGGTCAAACTCCTGGGC CTCAAGTGATCTGCCTGCCCCCTGCCTCCAACGTGCTAGGATTACAGGTGTGAGCCACCGTGCCCCCGGCCAACTTTGTCTTTTAAGTCCCCAATCA CAACTAACTTTTTTAAAAAAGGGTTCACCACGTTGCCAGCCACTCTTCTATGTATTTAAACAAATCAACCATTTCCTCCTCACAACCACTCTGTGGG GGGGTACTACTGTTATCACCATTTTAGAAAAAGGAAACTGAGGCACAGAGAGAGGTGGTTTTAACTTAGCCAATTTCACAGTGAGGAGTGGAGTGGC AGAGGGGTGTGGCTCCAGGCCCTGGAGGTCCTCTCCATACGCTAGACCATGTGTTTACCGTTAGTGCCATTCTTCATATTTGCTAGAGATCA ATTCTAGGAGTAGGGCTCTTGCTGCTCAAACTTTTTGCTTTTCTTAGAGGGGTTATGGATGCATGTTCATAACAGAAAGGGTACTCCTTGAGAAGGG ATTATAGGGCTATTATATTATCCCCACTGGATAAAAGAGGAAGCAGAGAGGTTCCAGTAATTCTCTCAAAGTCATTGCTGTGGAGCTTTTTTTTTGT CTGAAAGCAGTCTCTGACTCCAGAACCCTGTTTAGCACCCCTGTTCTCAGCCCCATGGCTCGCTTGGCTCTCCCCAGCATCTCAATGGGTCTGAAGG TAACTAAGCCATGGCATGTGGACTGTGGGGGTGATGGGCCTCACCCATCACCTTGTTCAGCCTCTCACTTCTCAGATGCGGACTTTTTTTTTGGAGA TTACTAAGCCATGGCATGTGGACTGTGGGGTGATGGGCCTCACCCATCACCTTGTTCAGCCTCTCACTTCTCAGATGCGGACTTTTTTTTTTTCAGA CAGAGTTTCGCTCTTGTTGCCCTGGCTAGAGTGCAATGGCACGATCTCGGCTCACTGCAGCCTCTGGCTCCAGGGTTTGTGATTCTCCTGCTTTCAG CCTCCGGAGTAGCTGGGATTACAGGCATCCACCACCACACCTGGCTAATTTTTTGTATTTTTAGTAGAGACTGGTTTTTACCATGTTGGCCAGGCTG GTCTCGAACTCCTGACTTCAGGTGATCCACCCGTCTGGCATCCCAAGTGCTGGATTACAGGCGTGAGCCACCGTGCCTGGCCTGATGTGGGGGGGTA TTTTGATGATGAAGAGGAAGAGAAGAAAATGTATCTTTCCTCCTTGGGGTTTCTTATTTGGCCTGTGACATTCCATTCCTCCCCTCCTCTATTTTTT GCCATTTTATTGACTTTTTCTAACTGGATGTACCTGGGTAGAAACTCCTCATACTATTGGCCCTGGTCATTGCTTTGTCTTTAGTTTTCCTTTTAGA AAAAGTCAAAAACAAAACAAGAAAACAAGAGGAGCCTCTATTTCTTTGAGGTGGAGGTAACTGGTGTACTTGTGCTGGTCCTGCATTGAGCTCACCT GCCTCCCCAGTGGCCAGTCCTTGGCCCCTGAAGTCAGGGATGATCTAGCTCTAGGCATGGCTATTCCATCCAGGGGGGTGAGTAGTGTATCTCTCCT AAAGTCCTGCTCACCAGGAGCTCCCGTCCCCCATACTACAGGTTCACATCCAGCTTTCAGGACTAGTCAGTCTATGTGGCCCTCCTCAATTAATAAA TCAGCACTATTTGCCAGGTGCGGTGTTTGTGCCTGTAATCCCAGCACTTTAGGAAGCTGAGGCAGGCAGATCACTGAGGTCAGGAGTTAGTTCGAGA CCAGCCTGGCCAACATGGTGAAATCCCCGTATCTACTGAAAATACAAAAATTAGCCGGGCATGGTGGTATGCACCCCGTAACCAGCTACTCAGGAAG CTGAGGCAGGAGAATCACTTGAAACCAGGAGGCAGAGGTTGCAGTAAGCTGCACTCCAGCCTGGTGACAAGAGCAAAAACTTTGTGTCAAAAAACAA AGAAAACCAAAAAACAAAGAAAAACACAAAAAACCCTTCTATTTGTTAAAAAAAAAAAAATCCACCGTGAACCAAAAATTAGTAAAAACAATGAACT AAAATTTTGTTTTTGCAAAATGTATGATAACAAATGTTAAGGAAGGTCATGTGCCGTTATGGTTCACTGCAGCCTTGTCTCCTGGGCTCAAAAGCGA TCCTCCTGCTTCGGTCTCCCTAGTAGCTGGGACTACAGGCTTGTGCCACCGCACCCAGCTTATTTTTTTTTTTTATTTTTTGTAGAGATAGGAGTCT TGCTTTGTTGTCCAGGCTGGTCTTCAACTCCTAGCTTCCAGTGATCCTCCTGCCTCAGCCTCCCATGTGCTGGGCTTTGGGACATTTTTTTATACAT AGTGCCATGTTACTATAAATGAGAAGTTTTAAAATACTGATTTTAAAAATTAATTTATGTCAAGAATTTTTTATAACCAAAGTTAAAAACCAAAACA AAAAATATGAAAGGGTTAATATCTTTGAGAGGTGATGAGAACTTATAAGTCAATAAGAGAAAACAAACATCCCTATAAAATGAATAAGCTAAGGACA TGAATGGGTAATGTACATAAGAAATGTAAATGTCTAGTAATATGCCAAAATAGATTTATTATTACTAATAAGCCACTTTCACTCTCTAGTTTGGAGA GTTGTTTTGAAAAATAGATATGTAATGATGGTGGAAAGATTGGTTTAACTATTCAGCAGGAAAATTTGGCAATTAGAAGTGTATCAAAAAGCCTTAG ATTGTTTCATAACCTTAGATTGGGAAATTCCACTTCTAGAAATTAATTCACTTCTAGAAATAATCATGAGTGTGCACAAAGATATTACCACAATTTT ATTTTACAGTATTATGTCTAATAGAGAAGAACTAGAAATAATTTAAATTTCCACCAATACAGGTTTGCCAATTACATTTTGTACATTTCCAAATTTG GTATATTATGTCCCTATTACAAATTATGTCCTAGAATATTTAATAGCATGGAAAAGTGTTAACAGTATTTTTTTAATGAAAAAAGCTTACAAAACAG TTTGTGATGATTCCATTTAAAATGTGTGTTTATTCATAGAACAAAGATTAGAAAAATAAACATTGATATATTAAAGGGTTATTTCATGGCAAATTGC AAATGATTATTTCCTTTTTTTGTGGCTTATTTGTATTTTTGAAGTTTTCTACAATGTAAAAGAATATTTTATGATATGAAAACTACAATACAATTTA TAATATAGAAAGAATAATTCGGCCGGGAACGGTGGCTCACGCCTGTAATCCCAGCACTTTTGGAGGCCGAGACCGGCGGATCACGAGGTCAGGGGGT TCAAGACTAGCCTGGCCAACATAGTGAAACCCCATCTCTACGAAAAATACAAAAATTAGTCAGGCATGGTGGTGCGTGCCTGTAGTCCCAGCTACTC GGGAATTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCCAGATCGCACCACTGCACTCCAGCTTGAGCAACAGAGTGAGACTTCGTCTCTACTC ATAAAAAAAAAAAAAAGAATAATTAACAGAAAATGGTTAGACACTTCCTTAGTGTCTCCTAAGTCAGGAGGACCCCAGTTGGGCAGGGATCCTCAAA TGGCCTCCTCCCATTTGGAGCATTATTGGAGGTCTTTTTCGGCCTCTTCGTCAAGTGGAATCTAGCTTCCGGTAAAACTACAAGTAACTATAAAGTT TGGGAGGTGGAAGAAATGCAACCGGTAGATCTCACAGAGTCTGTGCAAGAAACTGATTCAATGAGAATCTAGTTTCTCCGTCCACAGTTTCTCCAAA CAGAAACTAAGGCCGACTTTAGGGGCTTGTCCAAACCTAGGCAAGCAACTTAACAAGGTGAGGCCATGACTCCATGGCCTTTCCGTTCTGTTATATG CTGACTTAGACTAAAGCTCTCATACTTTAAAGTGCACAGAAATCTAGTTAAAATGCAGATTCTGATTCAGGTTAGGGGTGGGCCTGAGAGTCTGCAT TTCTAACCAGCTCCCAGGCGATGACCACGCACGGGACAGGTCTGGGATCACAGTTTAACTAGCAATGGTGTAGAACACAGAATCTGCAGCAAGAAGG CCAGCTTCCCATTCCTAGCTCTGCCACGGACCAACTGAATGACAGTTGCCTCGGTTTCCGAGTTTTCGTGAAGATGTAGTGAGTCATTACATCGTGA GGCTTTCGAGCAGCGTTCACTAAGAACTAGCTCTGACATTATTTATCGCATTCCTTAGAGCAAGCAGCCGGTGAAGTAGGGTTTGACGAATGAATAA GTGAATGAATGACCTTTGGAGAAAAATTGTTTCCTGGGTGACTAGAGTCCGAGAAGCAAAATGGGAGGGCCCGTGGGTGGGTAGGAGGCCCACCTCC TAGAAAGTTCTCTGCACCCGGTGGTCCAGAGGGCCTGGAGTGCCCGGAAGCCGGCCGGCTTGCGCTCAGCGGCCCAATGGGGCCGCGGGAGGGAGGG GAGAGCGCTCAGCCAACCCTTTCCGTCCGGGGCGCCGCAGCCCCGCCCCTCGGAGCGTTGCGACGTCCGAGCATTCCACGGTTGCTACATCGTCGCG AGGGGCGGGGCGCCTGTCAGGGAAGCGGCGCGCGCGCGCGGGCGGCGGGCGGGCTGGGGATCCGCCGCGCAGTGCCAGCGCCAGCGCCAGACCCGCG CCCCGCGCTCTCCGGCCCGTCGCCTGCCTTGGGACTCGCGAGCCCGCACTCCCGCCCTGCCTGTTCGCTGCCCGAGTATGGAGCTGCTGTGTTGCGA AGGCACCCGGCACGCGCCCCGGGCCGGGCCGGACCCGCGGCTGCTGGGGGACCAGCGTGTCCTGCAGAGCCTGCTCCGCCTGGAGGAGCGCTACGTA CCCCGCGCCTCCTACTTCCAGTGCGTGCAGCGGGAGATCAAGCCGCACATGCGGAAGATGCTGGCTTACTGGATGCTGGAGGTACCGCCCGGACGCG TCCCCCTCCCCCACCGCTCCCGGGTCTGGACACACCGGGGCCGCCCTGTCGGGACATCCCGGTCCCCACAGCAATCTGCAGGATGCTCCGAGGCTAA GACTCCCGGGGCCTGGCCTTTCACTAGGGCACCCACGCCAGCTGCCTCCCTTGCTTTCCCGAGCCCTAATCGGCTCCTCCCGACAGTGACTGCCAGT CACTTGGCACCCTAACTGTGCCTCTCTTCGGGCCGAGCAAACGGGACCAAGGACACTCTCTCCCCTTCGGCTTCTCACAGCGTCTCCCGCTTCCCTC CGCCTCCCGGCCTTCTCCGGAGAGCGCGCCTGGAAAACCCTGGGCTCGGCCGCCCCCGCCCGGGAGCCGGTTCCTGTGTCTTTCGCGGGGTTCTGGC GGGGAAGGCGATGGGGGTGGCGCGCGCCCTGTTCCGGCCGACAGGGAAATGAAAAGTGCAGGAGGCAGCGGCAGGAGCCTCCTCCCTTCCCCTCGGG TGTGTGCAGTGGTGGCGGTGATGGGGGTGAGGTCCCAGCTCTCTGGCTACCATGGGTGACCCTTGCGTCCCACTTCCCCTCGCTGTGGGGGAGGGGA GTCTCCGTTTGGAATCCTCCGTGAGCAAGGGCTCCTTGGCTTTACCACTCCCCCGTCAAGGGGAGAGGGGAGGAGGCCGCGCAGAGGAAGTGGGGGG CGTCACCTTGGGGAGGGCGCATCCTCCTCCTTTATTGGTCCTTGTCTCTCTAAGTAGCTTACCCTCTCTGCCGTTTTTGCTCCCTATCCCACCTCAC TTCAGCGCTCCCACCCCCCCGCTGCTGTGTTCCCCACGCTCCAGACCCAGCAGTGACTGTGCGCCCTCCCCCAGGTATGTGAGGAGCAGCGCTGTGA GGAGGAAGTCTTCCCCCTGGCCATGAACTACCTGGATCGCTACCTGTCTTGCGTCCCCACCCGAAAGGCGCAGTTGCAGCTCCTGGGTGCGGTCTGC ATGCTGCTGGCCTCCAAGCTGCGCGAGACCACGCCCCTGACCATCGAAAAACTGTGCATCTACACCGACCACGCTGTCTCTCCCCGCCAGTTGCGGG TGCGTGTGTAACTCCCCCCACCCCCGACACGTATTGTCTCCCCACTTTCCAGGAAAAGGAAAGCTTGAGATATCAGAGGCTTTCTGCCCCCTGGAGA GGAAGCAAGGGGATCAGGACCTTTGGGAAAGGAATTGGGGTGGAACAAACGATGGGGCATTGTGGTGTGATGGTTAGTATCACTCCCGCCCAGGCTT GAGCTGCAGGCAGGCATTAAACCCCCTCCTCCTGACCTCCAGGGGATGCCACTCCTTCCTGGTCTTTCCCCCAGATAGCAACAAGTCAAATTGCATG TCTACACTCACTAGTACTTTGCCTCTGGGTTTACGCAGCCACCATGAGTTATTTATTGGCAGCAGAAGGGCATGCCTGCACACCCCCACTGGAGTAG GGGAGTGGAATGTGCTTCATGTGGGGGAGGGGGTTTTGCCTTGGTTGAGTCTTTATCCTCATGTGGACTTTGTGATAGAAAAGCCTCCCAGAGCCAA TTAAAGCCAGGCCCTGATTGCTTTAAGGAAGGGCTGATGTATTTCATCCCACCTTCTTTGCTTCCTCTTATATCCCGGAAGAAACAGCTTCTTCCTA ATCCTTCCTCGTCCTCATTCTGAGGAACTGGAGCAGCTGCTTTGGGCCTGGTGGAAACAGCTCCCTCTTCCCCCCTTAGCCCAAGGCCCAAGCTGAG GGACAGACAGGGAGGTGAGCTGCATCTGCTTCCGATGTGATAATGGTGCCCCCTCCCCTGGCCCGCCCTCTCTGACCAAGGTCTTTCATAACCCTGT GGGGAGCTGCTGTCACTCCTGTGGTTTGGGAAGTGGCTCCCTGGGCCTCTTGCTGGAAACTTGGGCTGGGCTCAGGCCGGGCAGGAAAGTCACCGGT TCTGTCCCGCCTCAGAAGGAGCCTGGGGAGGAGGCGGGGGAGCTGCTGGATCTGGAAGAGGTTATTTAGGACATGCAGATTGTCTCCTAGGGAGGCT GGGGGAGAGGGTGGGTGAGCTGGCACCTTCCTCCACCTTGCTCTGTGGCGGGCCAAGTCTTCTGCTGACCCTGAGAGGAGTCTCTGGGCCCCATCTC CCAGGGAGGAGGGCAGCAAGCAGGCTGCTGTGATTGGCTGGCAGGGAAGCCAGGGTACTGGGGCCCCCGACTGCTGTGAGTCGAGGAACAGGATTCC TCTTCCTGCCAAGTAGCTCAGAGATGGGAGTAGGAGGCCAGAGTTGGGAATCCAGGAGGCGCCACAGCTCTTTGTGATGAATCTGGTAGTTTTTGGC AAGTCTGAAGGTGGAGCTAGTTTCCAGGGCCAGAGAGCAAGATGTTTTTGGAGGGGTTGGGGCTGGAAGGTAGAAGGGGAACTTCCTTTTTGTGAAA AGATGGAGGTGGTTTGTGTGCCCACGTATGAGGGTTTTTCAGTACAGGCAAAAAGTACTCTTCCCTCTGCCTGAGCTGGGGGTGGAGTGCCCAAAAG ACTTCCTAGAAGGTCAAGGTTGGAAGGGACCTCTGAGAACTCCAGTTGGTCCAAATCCGTGTGCAGCAGAGGAGGCTGAGGCCCAAGGAAGGAGGGC AAGGTCCTGCCTCAGCATCGCACTGAGCAGATGAGTGTAGAACCTGGGTCTTCTAGCTAGACCAGGTTGCCTTAAAAGTCAGGAATGTGATGGCCGC TGCCACCTACTGAAGCTAAGCACTCCCAGGGGTGTGTTCTCCACCAGTTAACACTGGGATTCTCTGGTTGCCTGGATATGGGGAAAGGTGGCCACTT TCCCTCAAACACAACCCCTTGCCTCCCCATAGGGAGAGTCCCACTCCCAGTTGCCTTCCAGATGCTTCCTTAGAAGCTGAGTCCCTTCTGTTTACTG CTGAGTTAGGAGTTGGCTCCTGGGACATGCACTAGGGGTAGCGTTGTAATTTTTCTGTCTCACTTCTGGCTCCAGGCCAGGCTATTTTCTCTGGGGC TCTGTGAGGGTAGGGGTTGATTTGAGAGGCTGACACCTAAGCTGGGGCCAAGAGAGAGACAGCTGTGGCTGGGGCCTGGAAGAGGTTGGGTGGGGTT GCCATTTCTGCCTCAATAAGGAGTCAAACCCACAAGTTCCTTCCTGAGATAAAACAATGAAGAAATCCTCATGTGTGCAACTCAGAAATGGGGCCAG GTCTGGGAACCCATGACGAGTGGACTGGGGTGGAGCTCCCAGCCTTCTCCCGAGACCTAGTACTGGCAGGTAGGCTTGGGTAGGTGAGGATAGGGCT TGATCCCTCTGGAATCATTTGGAGCCATCCTGTCTGGCTTGGCCTCTACCTATCCTCCTGAAAGTCAAGTGGCATGGGGCACTACGGGTTCCAGCTA AAGGGGGTGGGGTGGGGTGCTATACCTCAGGACCCATCCCTGATATCCTACCAAGGGGATGTGGCTTGGGTTGGGCAATCTCCCCTTTGAGGAACCT GAGAAAAGGCTCTGTGGCTGTCATTGGAGGAGTCATACTCCCTTCTGTTGATTCAAGAAGTGTGGACTTGGCTGGGATGCAGAGTTGCAGGGGAAGC TAGTGGTGATCTCCCCTTTCACAAATCCTTGGGGTTGAGAGAGTCTTTCTGCTTCATCCCAGAAGAGAGCCCAGTTCATGGTGATGCTGTGGTATCT GCTGCTTCCGTCTTTCAGCCCTGGCTGGAGAAATCCTCAGAGCCCTGAATGAAGTCAGGAGAAGGCCTGGATTATTGGCCCCTTAAACATAACCAGA CAGGATTAAAAGGGATAATCCATGTAAAGCATGTTGTCCTGGCACCTAGTAAATGATCAGTAAGTGCTCAAAGCACATGCCTCCTCCTCTTCCCTGC CTTGAACTCCATGGTGCCCGGCCTTAAAATCAGAAACAGAACTGGGGTCTTGGGCTTTAAAAGTTTGATGGGCTTCCCTGCCTGAGACTTTGAGACT TCTGCTTTGCTCCCTCCTCTTCTCTTCTCCAGCCACTGACCCCACCCTTTCCCCGCTTTTTCAGGACTGGGAGGTGCTGGTCCTAGGGAAGCTCAAG TGGGACCTGGCTGCTGTGATTGCACATGATTTCCTGGCCTTCATTCTGCACCGGCTCTCTCTGCCCCGTGACCGACAGGCCTTGGTCAAAAAGCATG CCCAGACCTTTTTGGCCCTCTGTGCTACAGGTAAGAGCCCTATGCACATTVTTGCCAAATTGGAAAAATCAGAAGACTTATAAGGGTGAGAGGTAAC TGAAGATTCTGGTTTATACTGTCAAAATTCCTTTGTGAAAATTATACCCCCTCTGAGCCCCCAGTCTCAATGCAGAAAAGCAGGTTATAATCAGCTA TATGGGATCTCAGACCCCTCCAGTTTGTAGTGGGGACACTGAGGGTATAGAGAGAAGTGACTTGCCCAAGGTCTCACAGTGAACAGGTTGGGAACAG ACCCCAGTCTCTTTGGCCCTAGTTGTGTTCCCATACTAGGGAGTGTCTTGTCTATTCCCGGGACCTATGGAAACTGGCAGTTGGTTCTGATCTCTAG GAAAGATACTCTTTCCTGTCTTCCTCCCTTGCTGATATCTTGCCCCACCCACTGCTGGAGTTTTCCAGCATGTCCTCTGCTCTACTCATGCTGCCTG GCACTTTCCAAGGAGTCGGAAGTCCATGCTGGCCGTTATCCTTCAGGTTTCCTTCTCTCATGGTTCCCTTTCCTCCTCTCCAAGATTATACCTTTGC CATGTACCCGCCATCCATGATCGCCACGGGCAGCATTGGGGCTGCAGTGCAAGGCCTGGGTGCCTGCTCCATGTCCGGGGATGAGCTCACAGAGCTG CTGGCAGGGATCACTGGCACTGAAGTGGTGAGTGCTGGGTAGCTGGGCAGCAGCCTCTCCATTCATAAATTAGTGCTTTGCCCTGAGCCTCCAGTAG AGGGAAACCTCCAACCCCAACCTGGTCCCAAGTCCTGGTTTCACAACCTTGGGGCTTTGTGGCTTTTTATCTCCTGCCTTGGTCTGGGGAAGAGCAA GTATCTTGGGTGGGGTGAAGCGCACTTGCCCTAGTGGTTCTTTTCTTGCCAAGTGGTGTGCTGGAGTGGGGGTGGGGGGTTTGGTGTCAGATGCAGG GCTGCTCTCACACTCCCTTGCCACATCCTCTTGCTAGTTTCTGAGAACTAAAGAGCGATTCCTGGGGCCGGGCTGTGGCCTAACCTCCCCAGACTTC CCCATGTGTTGGGAGCTGTCCTTCCCCTGCACCTGCTGCCAGATGCTATGGGGGGAGTGTTTGCTCCTCACTCTTCTCCCATGTTCCCAGGACTGCC TGCGGGCCTGTCAGGAGCAGATCGAAGCTGCACTCAGGGAGAGCCTCAGGGAAGCCGCTCAGACCAGCTCCAGCCCAGCGCCCAAAGCCCCCCGGGG CTCCAGCAGCCAAGGGCCCAGCCAGACCAGCACTCCTACAGATGTCACAGCCATACACCTGTAGCCCTGGAGAGGCCCTCTGGAGTGGCCACTAAGC AGAGGAGGGGCCGCTGCCACCCACCTCCCTGCCTCCAGGAACCACACCACATCTAAGCCTGAAGGGGCGTCTGTTCCCCCTTCACAAAGCCCAAGGG ATCTGGTCCTACCCATCCCCGCAGTGTGCACTAAGGGGCCCGGCCAGCCATGTCTGCATTTCGGTGGCTAGTCAAGCTCCTCCTCCCTGCATCTGAC CAGCAGCGCCTTTCCCAACTCTAGCTGGGGGTGGGCCAGGCTGATGGGACAGAATTGGATACATACACCAGCATTCCTTTTGAACGCCCCCCCCCCA CCCCTGGGGGCTCTCATGTTTTCAACTGCCAAAATGCTCTAGTGCCTTCTAAAGGTGTTGTCCCTTCTAGGGTTATTGCATTTGGATTGGGGTCCCT CTAAAATTTAATGCATGATAGACACATATGAGGGGGAATAGTCTAGATGGCTCCTCTCAGTACTTTGGAGGCCCCTATGTAGTCCGTGCTGACAGCT GCTCCTAGAGGGAGGGGCCTAGGCCTCAGCCAGAGAAGCTATAAATTCCTCTTTGCTTTGCTTTCTGCTCAGCTTCTCCTGTGTGATTGACAGCTTT GCTGCTGAAGGCTCATTTTAATTTATTAATTGCTTTGAGCACAACTTTAAGAGGACGTAATGGGGTCCTGGCCATCCCACAAGTGGTGGTAACCCTG GTGGTTGCTGTTTTCCTCCCTTCTGCTACTGGCAAAAGGATCTTTGTGGCCAAGGAGCTGCTATAGCCTGGGGTGGGGTCATGCCCTCCTCTCCCAT TGTCCCTCTGCCCCATCCTCCAGCAGGGAAAATGCAGCAGGGATGCCCTGGAGGTGGCTGAGCCCCTGTCTAGAGAGGGAGGCAAGCCCTGTTGACA CAGGTCTFTCCTAAGGCTGCAAGGTTTAGGCTGGTGGCCCAGGACCATCATCCTACTGTAATAAAGATGATTGTGAAATAAAACTGGCTTTGGCTTC TTGGATTGGTGTGTGGGTAAGTCTATTTCTGCACTGTATGAGGTAAGGAGGTGGTGTCAATGGTCTTGCAGGGATCATTTGGAGCCTTTTCTTTGTT AGGGCTGGATATTTAGGCTTTGTGGGGTACATGGTCTCTGACCCAATATAGTCAGTTCTGCTTTATAATGTGACCTATGCGTTCCTTAAAATTCACT ATGCCATGCAAAAATTGCACAAATAAAGACCACAGGTCTCATGGGGAAATGGGGCTTGAAGCACAACACTCAAATGAGTGACACATTAAAAAAAAAG GATAGCTTGGTTTTTACATATGTCAATGGTTGAGATATTATATCACAATAATATGGCCTTTTTATCTTTGACATGCACTTTTGCTTTTTTGGAAGTG GACGTCGGAAGGGTTGCTCACAGGTGGGGGAGATGAGTGGAGGTAGCTGGTACATGTTTAGGTGTGAGTTTTTGTGTACTACTTAGGCTTGGTTCAG CTAGATACAGTTTCCCATATTCACCTACTATTTCTCGAGGATGAAATCACACACAAGCAAACATGAAGTCTGCGTTATGATCAAACTGTTCCCAAAT ATATTAAATGGGTTGGAACAAATGCGCAATTTCGAAAGCAAATAACAAGGGTTATAGCAGGATTATACTTAAACTCTGCTGTTGTAGCACAAAACCA GCCACAGAAAACATGTAAATGGGGTGAGCATGGCTGTTCCAACAAAACTATTTATGGATGCTGAAACTGGAATTTCATGTAATTCCCTACCTCACAA AATACTGTTTTTAATTTTTTCCCCATTTAAAAAATGGAAAATCATTCTTAGCTCATGGGCCACACAAAATGGGCACTTGGGCTGGGTGCAGTGGCTC ATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCTCCTTTGGAAAACCCATA CCACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCACGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGAGAATCTAT GAACCATGGAGGCGGAGGTTGCAGCGAGCCGAGATCATGCCACTGTACTCCAGCCTGTCGACAGAGCGAGACTCCGTCTCTTCAAAAAATCAACA AAAAAAGGGGCACCTGGCCCTAGTTTACTAGTCACTAGTCTAAAGCTTTCATTGGCTGAAAAGCCAGAAAGGGAGCCTGTTGATCTAGCTCTGAT CTAACCATTCTTGGGCCCAGCCTTATTCTCTGGCCTTTTTTTTTTTTTTTGAGACAGTCTGCTCCGTTCCCAGGCTGGAGTGTAGTGCCCCCCAA TCCTGGATCACCGCAACCTCCACCTCCCAGGTTGAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGATTACAAGCACACGCCACCACACCA GCTAATTTTGTATTTTAGTAGAGAAGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGAACTCAGGTAATCCACCTACCTCAGCCTCC CAAAGTGCTGGGATTACAGGCGTGAGCCACCAAGCCCAGCCTCTCTTCCTTTCTTGACTCTTATCTCTGCTTTCCCTTAGTTTTCTCTTTTGTAG TCCTTTCATCCACTGCTGAGACACGACCATCTTTGGACAACCTGCTCCTGGCTGCTGTAGCCTGTGATGGGGGAAGGCAGAGGATGTGTCTTGGG GGCTAACAAGGTGAGTGCAGCCTGGAGAAACAAGCTTGGAGATCAAGGGAGGTGGGTCCTATATAAACAGGACATGTATGTCCTCCGTCCTCCAT ACTAACAGGAGTAATGCCTACCTCCATTGACTACACCAAACACAGAGGTTCAATAAATATCTGTCTTTGCCTTTATCTCAGTGACAGACACAATA GCCATAGAAAAAGTACTCACACCAAGCCCCAGCTGGGGACTGGGAATGCTAGCATATGGTATCTCTGTTGGCTACAGTCTTTCATGGGGATAAGG GCCTAGATGGAAGAGGGAACCAGCCAGACCCTCAGTCCTTCCTGTCCTGGAAGGGAGCTCAGATGTCCAGTGATCTGTCACTGCCCCCTGATCTG GGTCTTCAGCCATTAAAGCTCAGTGTCATCTTCAGTCACCAACGGGGGTCTTGGTGTTCCTTCCWCCCCTTGGCCAGGACAGCTGACTGTTTTCC TCACTCCACGGTGATGGGACATCTTCCACATCGCGGGGGACTGCACTCTGAAGCTCACGCCTGATTTCTGCGATAGCTGTGGATTTCTGTTTTCC CGGAGCAGTTCTAAGAGGGCCTCTTTCTGGTCTGTGGCCAAGTCGGCCTTGTAGCGCTGGACCNGTCAGGAGGCACTGGTGCCATGGGCATGGCA GTTCACGCTTCTCTGTCCGGACCCCAGGAAGTGGAAGACTAGGGCATCCAGCACCCGGTTTTGTGCATACTTCTTATCCAGCAGCAGTCGCAGGA GAAGATGCTGTTGGCACCGCTGTATTCCATCTCAGCAATTTTCAGCATGGCCGCACTAGTGGGAAGGGAGGTGGGGTAGAGTAAGCAGGGAAACA TTGGAAGAAGGATCCTACTTCTCCCTCTATGCTTTCCCCTTTTTTTCTTCCCCTCTGCTGGCCATACATATGGTATTCCCCAGGGACCTTTCTTC CTACACATCATATTATACTCCCTTGACCTCAGTCACCATCTCTACAGGGATCCACCCTTCTCTATCTCTAGCATAGACTGCTTGTTTTCAGTAAC CAACTAGAGTATGGTCCAACATCTCAACGTCTCCACCCTAACTACTTCTTCCTGTGTTTCCTACTCATTTGTTTATCTATTTACTGAGAACTTAC TTTATGCCAGGCACTCGGGCCCTGTTGTTGCACAACTTACATTGAGGGGATAATGATACACCTACTCATTGGCTTAAACAAGCACAACCCAAGGC TTTCCTTAGCTCCTTCTCCACTCTGCCCATTCCCAAGTCCTGGCAATTCCACTATCTGGATATCCACTGACCAGCCCCCTTCCACCCCCTGTTAC TACCTGGAGTGCACACAGGGATGGAGCACTTGGTGATGATGCTACCCACAATGATGGCTTCCCGGAGGGTACTGTGCCAGACTCGCACAGTGGAA TCAGGATCCCTAGGGAGAGTCAAAGGGCAGCCACTGTGAGCCCAGGATGAGAAAAGGAGTTACAGCAGGAAGCATTCCACCCAGCCCAGGGACAG CTAGCATTTCCCACACCAGGCCTGCTGTGTTCCCCATAGAGACCAGCCCTTCCCTTCTTCCGTGCCTCTGGGATCCTCCTTTGAACCACCAGGCT CCAGGTTTGAAAAGGGCCTTCTTGAGAGCCATGTAGAGATGGAAGTTGAGTCGTTTGTATTCAGCTCGTCATCTCGTACTCGAGGGAGCATACT GGTTGTAGAAGCGCTGGGCCATGTGCGTTCCTTCAGGTTAGAGGCAAATCCTAGTGGGAGAGTTAAGCGGGAAGTTCCAACTCACAGACAGTCTG GACCCGGCCCATTAAATATCACCATGGATAGTGCATACAAGAGGTTTAAAGTAAAATATTGACCTTTCTTCAGTGTGGGATGTGTGGGAGGCTGT GTGCATGCAACACCCATCAGCTTAGAGAGAGAATAGGAGGGCAATGAGATATACCCAAATGAGGAGCACCGTTTGTCTGTTGAGAGCCAGAGCTC GTGCAAACTGATGGCTACTCAGCATCAGTTCGATTCTGCTAGCCCTGAGCATGCCTGGGCAGTACAGACTTCTGAGGTCCTGCTACAGGGTTGTA TCCCAGTGGCTATAAAAGCCTCTCCCCTAGAAATTCATCACAGAGGGTTGTATCCTGTAGCTATTTAAGCTCTCTCCCCTAGTTTCATCACGGAG GGTTCCTAACTGGCTAACTGGGTCTTGGCCCCAAAAATGACACAGGAAAAGCTAGAAAAATGATGCTATAAAGTAGCACCAGAGGGCCCTGGGGC AAAGCTCAATGCCCTGGGGCCAGAGGCAAGGAAAGCCTGTCCGTCCCAAACTCAGCCTGCACCTATTCCCCTGGCCCCCCGTCCCCCCAGCTACT CTACCTGGTGGCCTGGTACATGGCAGCTGCAGTCCAGGCCTCCGGCTCTGTGACGTAGAGGATTTGCTCCCAGTTGGAGAGTGTGGATGATCTTA AATGCCTTGGGCAGTTTTCCACTGCGGTACTTAGATAATACCTAGGGATGAGGGAGGTAAAACAATCTCGTCATCCACATATGGCAGCTTGCTGT GGGCTAGGAACTTGTCTGGTGCTTTTAATATATTAACTCATTGCATCCCCACAATAACCTATTGGAGGTGCCATTATTATGCTCATTTTACAGAT GACCAGTGAGAGTTCCAGTAACCGACCCAAGGATGCCAAGTCATTTACAGGCAGAGCAGGAATCTGTCCTCACACTCTGCCTTTAGGTCTGTTTT TCTACTCCCATGACTTCTTTAGTATGCGATGCAGGCAAAAGGCAAAAAGCCTGTGGCAGGAGCCCACAGCCCCCAAAGGGGTCTTCCACTTGGCT CCCCTCTCAGCTCTTACCTCCCGGACCCCCCTGTACACTTCTAGGACCCGGGGGTCCAGCTGGGGCATATGAAGCCCGATCCTCTGACATGACTG TCTCAACCTCTGTCTGCTTCTCAGTCAGCTTCTCCATGATGATGTCAGCCAGGGTGCGCCTAAGAGGGGAAGTGCCAAGAGGAGGGAGAGAGGGG CAAGGAGCACTGTGGTCACTGTCCAGGAAGCTCCAGACTCCCCACAGTCCCCTGTGAGCACCGCCATACTGCGATCCTGCTGGGATGCAGCTTAG AGTTCTCTCTCTGTGCCCATTCATCCACCACAGACAGAATCACTGCAGGGTGCAAAGGTCTGTGTCATTCCATTTAGGACTGCTAGCAGTTGTTG TACGGAGGTTATTATGAACCTCACTCTGAGTCAGTCTGCCCAGGTTCATCCTGGCTCACCCACTCCCTGGTATTTCTTTGGGGCATTGTTACTTT ACCTCTCTATGCCTCTGTTTCCTCATTTGTAAAATAGGATAATAACGGTACCCACCTTAAAAGATTAATGGAAGGTTAAATAAGTTAATGTCTGT TCATTACTTGGAATGGTCAGTACACAGTAAGCGTTATCTATGGAAATATTTCTAAGACTGATTATATTCTTTTTGCCTCCTTTTCAGTATTGTTG GGTGTATCAACATAATCTTATCTTAATGATTCAGAATTACCATCGCCTTGAGCTGTCATATAATACTAGCATCTTCAGATCTGCTGTGAAGTATT TATTTATTTTTTTTGAGAGAGAGTCTACCTCTGTTGCCCAGGTTGGCATGCAGTGGCACCATCATGGCTTCTGTGCCTCTATCTCTCTGGGGCTT GCGATCTTCCCGCCTCAGTCTCTCGAGTAGCTGGGACCACAGGAACATAGTACAAGGCCCAGCTAGTTTTTATTCTTCTGTAGAGATGTGTCTCC CCATGTTGCCCAGGCTGGTCTCACACTCCTGGGCTCCTGCCTTGGCGTCCCAAAGTGCTAAGATTACAGGTCTGGGCCACTTGCCTGCTGAAAAT GTATTTAAGCTGCTTCTCAGTTGGGCGCAGTGGCTCACGCTTGTAATCCCAGTACTTTGGGAGGCTGATGAGGTGGATTCGTGAGGTCCATACTC TTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAATAAAACAAAATTAGCCAGGCGTGGTGGTATTGCCTGTTTCCTGCATACCTC GAGAGGCTGAGGTTGCAGTGAGCTGAGATCATGCCACTGCCCTCCAGCGTGGGTGACAGAGTGAGATCCTGTCACAATCCAAAAAAAAACAAACT GCTCCTCTTTTCTGAGGTCCTACTCAATGCCAGGCACTGAGTTTGGGACTTTTCAGTCCTAGAGTCAGCGCAACACTTATAGGACACGGNCTTAT GCAGACATGGGAACTGGGCCTCAGGTTAATAATCACCCAAGGCCTCACAGCTGTCAGGTGGGGGTAAGAGTCAAACTCATTTTTTTTGGTGTCTG AGTTAAGGTGCTTTATAGTACCTTATAATGTGCCCCCAAACTATTGCCTCTGATTGTTGAATTCATGTGTTCTATCTTGCTTTTTTCTGTGATGC CAGCTATCATTTCTTACGACTGCCAGGAGTTCTGATTACTTCAAGGAGCTTGTCTACTCTATTTACTACAAGCTGGAAAGCATTCTGCTTTTTTG TCAGCATTATCAGTGAAGTAGGAGTTATGAGGTGCTGAGTGAGAACAGAGAGGCTCTCTGGGGGGACAAGCCCTGTACATACTTTATGATTTATA TTTCACTGTTAGGCATCAATCTGGGAGAGGGGCTCATTTTCATTTCTTCATTCTGCATTTTCAAATTGCTGCCACAGAATTTATTTGCCTCCCTG TCCTTTTATAGTATGATTAGCAATGAGATGCATTAGCCCAAAACAGCCTAAAGTATCAGGGACACCATTATGTTAATATCACAGGTCAGAATGTC TGGTTGAGGACCCTTATCCTAGACTCCACTCCCAAGGGCCAAAATTTATGGGCTCAGGAGTTTGACCACAGGCAGTCTAATGCCCATCATTTTGG AGCTAGCATTTATTATAGATGGGAATAAATTAGTGGTCCTGACTAGGGCTTTCTTGCCTCCCAGAGGACATTTGCAATGTCTATGTCATTTTTTG GTTTTCACAACTGGGGGAAGGTTGCTACTGGAGTCTAGAAGTAGAGATCAGAGATATCTACTAAACCTCCTACACTGCACAGGACAGCCTCCACA CACACAAAATTACCCAGCCCAAAATGTCAATAATGCTGAGGTTGAAAAACCTTGGCTTAAATGAAGCTTAGGATATGAAGACTTGTCAAGAAGTT GAGCTTACCGCTAAAAAAACTAAGAATACCAAAACCAAATGCAATAGGATGGCTCTCCCCAGAGGTGTAAAAGGGCCTGGAACTGTTCCCTGGCA ACTGGGCAGTTGTACAACAAATGGACATAAGGACACAATGTTTTTGAGGCTGGGTCATTCCTACTCACAGTGGTCCTTTGAGGATGGCCAGTTTT GTCAAGGTGGTCCCCTACAGCTAGCAACTCCAGGGCCCTTTCCGGGGTAGGGAATCATAAGTCTGCCAGGGAACTTGTTTTCCTGTGGGTCTTTC TACAAGGACTCATTATCCCAAATCCCCAGGCCTACCTGGCAGGAGGGTTATGTTCATGAACATCTCTATGGCACGCTCATCCTCAGGGTCCACTC CACCTCTGCATGATGGCCCGCTGCTGTCATTGTGGCAGCCTTCTCCAGGGTGGGCCACTCCTCGTCCTCGTCATGATCCATCCTGAGGCATTCTT GGACCTAGAAGAGGGGAGACTAAATGGATGAGCACAGCAAAAGGTAGCTGAGGATTTCGTCAGTTTAACTTTAGCCATTATGTAGTACAGGCTCA CATGTGGTTGTGATAGACGCAGGTATGTGCAGTGAAACAAATGCATTAGCTCCCTGTCCCCAGGGTTGCAATCATGCTTGAGAAACAAAATGTAT ATACAGGAAACAATAAGAAAAGCAATGGCCATAAATAATAGTTAACATACCATACTCAGTTATGTAGAAGGAACTTTTTTTTTTTTTTTGAATGG AGTCTTGCCTGTCACCCACACTGGAGTGCAGTGGAGGATCTCAGCTCACTGCTGCTCCGCCTCCCGTTTCATGCCATTCTCCTGCCTCTCAGCCT CCCAAGCAGCTGGGACTACAGGCATAAGCCACCAGCCCGGCTAATTTTTTGTATTTTTAGTAGAGTTGGTTTTCACTTGTTGACTGAAATGGTCT CGATCTCTTGACCTCGTGATCCGCCCCGCCTTGGCCTCCCAAAATGCTGGGATTACACGTGAGCCACTGTTCCCGGCCTGTAGAAGGAACTTCTA AACACTATACCCATGTTAACTGTTTAATCCTTATAAACCCAAGAAGTGGCGGGCANNNNNNNNNNNNNNNNNNACGGTGGCTCACGCATGTAATC CCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAGGTCAAGAGATCGAAACCACCCTGGTCAACATGGTGNCCCCATCTAACTTAAAATTACA AAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAGTCCCAGCTATTTGGAAGGCTGAGGCAGGAGAATTCTTTCCCAGGCAGGTGGAGGTTGCAGT GAGCCAAGGTCACGCCACTGCACTCCAGCCTGGTGACAAAGCGAGACTCCGTCTCAAAAATATATATAAATTAAAAAATAAAAAATAAACCTTCT TATGGACIATGGCAAATAATAAATAAATAAGAATAAACCCAAGAAGTGGATACTATTACTATACCCAGTTTCNTGAGGACAATTTGAAGCACTGA GAAGTTGGGTAATTTGCCCAAGATGGTAGTCTGGGTCTAGACTGCATTCTTTCGCTATTCTACACATATTCTGTTTGATTATATGCCACAAATTG AGTAGTAGAGACAACATATGCACTTAAAGGATGAGTGGTGAGGACAGTTAGGAGCTGGATGGGCAGTTTGGGAGCAGGGAGTGTGTTCCAGACGC AGAGAAAATAAGGCTTGGATATAAGAGTCTCCTAGGCAATAGCAAGAAATAATGCTAGGTACGTGGGNGGTGTGCCAGACTGGAGAGGCTTTTAA ATTCAGGCAGTAGAGTTCAGATTTCATCCACAGTCCATTTAAATACATGAAGTTGGCTTGCGTTTTTCTCACGGGCCTGTAATCCCACCATTTTG GGAGACCAAGGCGGGTGGATCATGAGATTGGGAGTTCGAGACCAGCCTGACTAACAGGGAGAAGCCCCCGTCTCTACTAAATACAAATTAGCCGG GCTTGGTGGCGCATGCCTATTTCCCAGCTACTTGGGAAGGCTGAGGCATGAGTTCGCTTTCCCTGAGGTGGAGGTTGAGGTGGTTAGGTGAGCCG AGATCGCGCCACTGCACTCCAGCCTGGGCAACAACAGCAAAACTCTGTCTCAAAAATAAATAAATAAAATAAATAAAATAAATAGGCCGGGCGCG GTGGCTCACGCCTGTAATCCCAGCACTTAGAGAGGCCAAGGCGGGCGGATCACGAGGTCAGGAGACTGAGACCATCCTTCTTATCTTTGAAACCC CGTCTCTACTAAAAATACAAAAAATTAGCCGGGTGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCATAGTTGGTGTGAACC CGGGAGGCGGAGCTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTTAAAAAAAAAAAAAAATGAA GTTAGTCCATTTAAATAACTTCTGTTTTGGAAGGCTACATGTCTGGGCATCTGGAAGGGGTCTAATAATCCAAGTGGGGAGCTATAATGCTACGT ATCAATAGGTCATTAACACAAAGGCAGTGTGTGATAACACTAAATAAGGGGGAACAGACTTTTTGTCTCTCGTTCCTCGGTCCCCCCCAAATTTG TACTTTGTAGGTGGTTCTCCTTAGTGCCAGACCCTAACTCCAGGTGTCTCCTGTAAGCTGCTCTTGGATGACTCAGGCACCTCAAATCTCACCCG TTATCACTAAACTAATTTTCTTTCCCTCCTAGGTCTACACTGCTAACCATCCACAGCTCAGTTCGGCACCATCGTCCACCAATTGCTAAGCCCTG GGAGG HUMAN SEQUENCE—mRNA GCGCCTGTCAGGGAAGCGGCGCGCGCGCGCGGGCGGCGGCGGGCTGGGATCCGCCGCGCAGTGCCAGCGCCAGCGCCCAGACCGCGCCCCGCGCT CTCCGGCCCGTCGCCTGCCTTGGGACTCGCGAGCCCGCACTCCCGCCCTGCCTGTTCGCTGCCCGAGTATGGAGCTGCTGTGTTGCGTTTCCCCG GCACGCGCCCCGGGCCGGGCCGGACCCGCGGCTGCTGGGGGACCAGCGTGTCCTGCAGAGCCTGCTCCGCCTGGAGGAGGAGCGCTACGTACCCG TCCTACTTCCAGTGCGTGGGGCGGGAGATCAAGCCGCACATGCGGAAGATGCTGGCTTACTGGATGAGGATTATGTGATAGCAGCAGCTGTGAGG AGGAAGTCTTCCCCCTGGCCATGAACTACCTGGATCGCTACCTGTCTTGCGTCCCCACCCGAAAGGCGCAGTTGTGCTCCTGTTGCGGTCTGCAT GCTGCTGGCCTCCAAGCTGCGCGAGACCACGCCCCTGACCATCGAAAAACTGTGCATCTACACCGACCACGCTGTCTCTCCCCGCCAGTTGGGAC TGGGAGGTGCTGGTCCTAGGGTGCTCTGTGGGACCTGGCTGCTGTGATTGCACATGATTTCCTTCTTCATTCTGCACCGGCTCTCTCTGCCCCCC GTGACCGACAGGCCTTGGTCAAAAAGCATGCCCAGACCTTTTTGGCCCTCTGTGCTACAGATTATACCTTTGCCATGTACCCGCTCCATGATCAA CACGGGCAGCATTGGGGCTGCAGTGCAAGGCCTGGGTGCCTGCTCCATGTCCGGGGATGAGCTCACAGAGCTGCTGGTGTATCACTTCACTGAAT GTGGACTGCCTGCGGGCCTGTCAGGAGCAGATCGAAGCTGCACTCAGGGAGAGCCTCAGGGAAGCCTCTCAGACCAGCTCCAGCCCAGCGCTTTG CCCCCCGGGGCTCCAGCAGCCAGGCCCAGCCAGACCAGCACTCCTACAGATGTCACAGCCATACACCTGTAGCCCTGGAGATCCCTCTTAGGGTG GCCACTAAGCAGAGGAGGGGCCGCTGCCACCCACCTCCCTGCCTCCAGGAACCACACCACATCTAAGCCTGAGGGGCGTCTGTTCCCCCTTTTCT AGCCCAAGGGATCTGGTCCTACCCATCCCCGCAGTGTGCACTAAGGGGCCCGGCCAGCCATGTCTGCATTTCGGTGGCTAGTCTGCTCCTCTCCC TGCATCTGACCAGCAGCGCCTTTCCCAACTCTAGCTGGGGGTGGGCCAGGCTGATGGGACAGAATTGGATACATACACCAGCATTCCTTTGTCCC CCCCCCCCCACCCCTGGGGGCTCTCATGTTTTCAACTGCCAAAATGCTCTAGTGCCTTCTAAAGGTGTTGTCCCTTCTAGGGGTTATTGTTGGAT TGGGGTCCCTCTAAAATTTAATGCATGATAGACACATATGAGGGGGAATAGTCTAGATGGCTCCTCTCAGTACTTTGGAGGCCCTATGTAGTTGT GCTGACAGCTGCTCCTAGAGGGAGGGGCCTAGGCCTCAGCCAGAGAAGCTATAAATTCCTCTTTGCTTTGCTTTCTGCTCAGCTCTCCTGTGTTT TGACAGCTTTTGCTGCTGAAGGCTCATTTTATTTATTAATTGCTTTGAGCACAACTTAAGAGGACATAATGGGGCCTGGCCATCCACAAGTGGTG GTAACCCTGGTGGTTGCTGTTTTCCTCCCTTCTGCTACTGGCAAAGGATCTTTGTGGCCAAGGAGCTGCTATAGCCTGGTTTGGGTCATGCCCTC CTCTCCCATTGTCCCTCTGCCCCATCCTCCAGCAGGGAAAATGCAGCAGGGATGCCCTGGAGGTGGCTGAGCCCCTGTCTAGAGAGGAGGCTGCC CTGTTGACACAGGTCTTTCCTAAGGCTGCAAGGTTTAGGCTGGTGGCCCAGGACCATCATCCTACTGTAATAAAGATGATTGTGTAAATTTCTTC TTTGG HUMAN SEQUENCE—CODING ATGGAGCTGCTGTGTTGCGAAGGCACCCGGCACGCGCCCCGGCCGGGCCGGACCCGCGGCTGCTGGGGACCAGCGTGTCCTGCAGAGCCTGCTCC GCCTGGAGGAGCGCTACGTACCCCGCGCCTCCTACTTCCAGTGCGTGCAGCGGGAGATCAAGCCGCACATGCGGAATGCTGGCTTACTGGATGCT GGAGGTATGTGAGGAGCAGCGCTGTGAGGAGGAAGTCTTCCCCCTGGCCATGAACTACCTGGATCGCTACCTGTCTTGCGTCCCCACCAAAGGCG CAGTTGCAGCTCCTGGGTGCGGTCTGCATGCTGCTGGCCTCCAAGCTGCGCGAGACCACGCCCCTGACCATCGAAACTGTGCATCTACACCGACC ACGCTGTCTCTCCCGCCAGTTGCGGACTGGGAGGTGCTGGTCCTAGGGAAGCTCAAGTGGGACCTGGCTGCTGTGATTGCACATGATTTCCTGGC CTTCATTCTGCACCGGCTETCTCTGCCCCGTGACCGACAGGCCTTGGTCAAAAAGCATGCCCAGACETTTTGCCCTCTGTGCTACAGATTATACC TTTGCCATGTACCCGCCATCCATGATCGCCACGGGCAGCATTGGGGCTGCAGTGCAAGGCCGGTGCCTGCTCCATGTCCGGGGATGAGCTCACAG AGCTGCTGGCAGGGATCACTGGCACTGAAGTGGACTGCCTGCGGGCCTGTCAGGAGCAGATCGAAGCTGCACTCAGGGAGAGCCTCAGGAGCCTC TCAGACCAGCTCCAGCCCAGCGCCCAAAGCCCCCCGGGGCTCCAGCAGCCAAGGGCCCAGCCAGACCAGCACTCCTACAGATGTCAGCCATACAC CTGTAG

[0298] TABLE VII MOUSE NOMENCLATURE ICSGNM  Wnt3 Celera  mCG19162 HUMAN NOMENCLATURE HGNC    WNT3 Calera  hCG27972 MOUSE SEQUENCE—GENOMIC NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNMNNNNNNNNNNNNNNNNNNNNNNNNMNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NMNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGCTGCCAGCAACCAGGCCCTTCT GGGGCCAGTTCCCTCCGGGCAGATAGATCAGCTGGCCCCAGGGGTGCAGGATCCGAGGGGTCAAGCCCCCAGAGTGGCAGCTTTGTGTGATGGAATG AGGCTTAAACTCCAGTTGGCAACCTTCAGTACATTCATGGGGGCAGCCACCACTGTGTGCACACAAACAAGCACCACTGTGCGCACACAAGCAAGCA CCTCTGTGTGCACACGAGCAAGCACCACTGTGTGCACACAAGCCAGCACCACTGTGTGCACACAAGCAAGCACCACTGTATGCACACTAGCATCACT GTGTGCACACAAGCCAGCACCACTGTATGCACACAAGCCAGCACCACTGTGTCACACGAGCACCACTGTATGCACACAAGCCAGCACCACCTGTGTG CAACCAAGCAAGCACCACTGTGTACAAACAAGCACCACTGTGTGCACCCAAGCAAGCACCACTGTGTGCACACAAGCAAGCACCACTGTGTGCACAC AAGCATCACTGTGTGCACACAAGCAAOCACCACTGTGTACAAACAAGCACCACTGTGTGCACACAAGCATCACTGTGTGCACACAAGCAAGCACCAC TGTGTACAAACAAGCACCGCTCTGTGCACACAAGCAAGCACCACTGTGTACAAACAAGCACCGOTCTGTGCACACAAGCAAGCACCACTGTGTGCAC ACAAGCAAGCACCACTGTGTGCACACAGGCACATGTGCATGCTGCACCCCAGCTTTCTCTTACCCACCTCCTTCTGGGACCCTGAAATCTCTGTGAC TGCTTGGAACATGCTAAGAGGTCCATGGACACCACCCAGTCCTGTGAGTAGTAAGTACCTCCTGGGCTAGATATGACCCTCACCTATAGCAAGTGTC CGCAGAAOGCTGAGGTAGCCACTTCTAGGGACCCACAGCTGAGTTCCTGTTCAGTGCCCTGGTCTGTCCTGCAAGGTAAGGACATCAAGGATAATGA CCATTAGTAATGGTGGAGAAACGAAGCATCTAGTCTAGTTAGCTGTCACOGCCAAAAGGACTCTTAATTAGGCCACGTTAATCTATAGGAAGGGTCA TAGTCAAAGAG0GTAAGTGAGCATGCAGCCCAACGACAGAAAATCGGCCAGGGACCCCTTGGCTCCCCACCCACATCCTCCCAGCTCTCACATTCTG ATGGAGGACAACAGGTAGAGACTAACAGCTTTTCTGGGCCCTGGACTGTCTACCTTGTCTGAAGTCTACAGTGTCTGAAOTAGGTATCTGAACTTGA CCCAGCCCTCTTCCTCGCCTTCCTCCTCCCACTCCTGAAGAAAGCTTCTCACAGACCAAAGAAGTGATCACTGGCATCGCCAGGCTCCTCTGGCAGC TGAGAGGCCGTCACGCTTCCTCCTTACTGGGAATATCTGGGTCGCAGAGGCCTCCGTATGACCCATACTTTCACCCCACTTACTCGTAAGGCTGGAT TGGTGTCCCCAAATATGTCCAATACTTTGAGACGGGGTGGGGGTGGGGGGTCATGGCCATGGAGATTCCAGATGCAGAGGAGGGAACTCAGTGCCAC CTTTGGCTGTAAGGAACAGCCTCAATTGGGATTAGGAAAATACACCATCTTGAATCATAAACAAACAAACAAACAAACAAATAAATAAATAATCTTG AATCACAAACAAACAAACATTCCAAGACGGGATTCTCAGGGCAGTTAATGTCTCAGCAGTGGCTCAAGAGACTCAGTTTCTCCCACCCTGGTCTTAA GTCTCTACTTTGGTCTCAGTCAGTTGTTCTCACAGCATCCAACCAAGATATAACAATACCCCAAAGCGGGGAAACTGGACAGCAATTTAGCGGACTG CTCACTCCCCTAAATACTTTCTAGAAATCACAGGTCCGTCAGCTGACTCCCCTTCGTGTCTCCTTTGAGTCGGTGTAGCCCAAGCCGTTGCAAATTG ACTCAGACTAGTCAGCATTTATCTCTGAGCCAGGTGGGGGAGAACAAACTTGGTTCCTCATGTGCCTAAATAAAGGGTCTGCCTTTACATATACTTT TATATACATATATGTGTATATATATCATCCTAGTCAGGATTTCTACTGCTGCACAAAACATCATGACCAAGAAACAAATGGGGGAGGAAAGGGTTTA TTTATCTTATACTTCCACATTGCTGTTCATCCCCAAAGGAAGTCAGGACTGGAACTCACACAGGGGAGGAAGCAGGAGGCAGGAGCTGATGCAGAGG CCATGGAGGGTGCTGCTTACTGGATTGCATCTCCTAGCTTGCTCAGCTTGCTTTCTTATAGAACCTGGGACTGCCAGCCCAGGGATGGCACCCCCCA CAGTGGGCCCTCCCAGCCTTGATCACTAATTAAGAAAATGCCTTATAGCTGGATCTGATGGAGGCATTTCCTCAAGGGAGGCTCCTTTCTCTGTGAG AACTCCAGCTTGTGTCAGGTGGACACAAAACCAGCCAGTACAGTTACTTGCAACCATAAGTAACTCCAGTTCCAGGGATCCTGACCTCTGCAGGCAT CGAGCAGGTGGATGGCATACATGCATACAGGCAAAACACTCGTACGTGTAAAAGAAGATAAATCCALAATAGTAATAATAATAAAAAGTAACTCAAA AGAACTTTCCTCCTCACTCAGCTCAGCTACTGCCAGGAACCATTTCAGAGCCAGCAGGCATCACCACTGCAGGCGAGGGAATAGGCTTAGAGAGCAT AGGAAACATGAAACATGCCCAGGGTTGTACAGTACGAGGCAGAGCTGGGGTCTAAGGCAACCACTCAGACAGTGTCTCCCTGGACAAACAACCGAAA TCCCATAGGACAGATCCTGAGAGGCCAGCAATGCTAAGCAGGGTTTGCCCAAGGACCGCCCCCCACCACCTGTGACAGCTATAAACACCTGTTCCAG GATCTTTGCTGGTGAAGTAGCGAGGGCCCCAGCGACTGTCCACTGAACCATCTACTTGTGTTCAGACTCTTAGGGGGTAGAGCTCATTTCTGGTCCA ACCTCAGTTTCCCCACGGTGGCTGCTGTTGGTCATACTTGTCTGTGAAGGGATGGTTGGGGGCAGAGATCTGGAGGGTGCAAACCAAGCATGATGGG CAATTGTCTGCCCTATATCCATGGATCAGACCAGGCTACTCGATCCCCCCCCCCTTTTTTTTAAATAGTGTCCCCACURGACTCTTCTCCCAAGAGT CTGGCTGGCTCTTAATTTTGCTGTTTAGAAACATTTGATTTTCTGAGGTATGCCTCTTCCAGGAGAAGGTAAGCCTCATAGACTCAGAACCCTGGGG CTCAGGCATGCTTACCTGGGGGTTACCTGCATATAGTCCTTCTTAGTGAACAACTAACTACACAGGACACCTATGCAAAGAACACCTGGGAGCTCTG TAATGGCATGCACATGTGTGCACACCACACACACACACACACACACACACACACAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA GAGCGATCATTGTGGCTGGAGGGGCTGTCAAGTCTCAGATGCCTCCAGGTGTCAGTGACTTCTGGCCAGGTTGCTATGTTCTCATCTCAAGCCATCA GGAAAGGTGGGTGTTACCTTGAGGAAAACTGAACCCAACACTGGGGTGGACAGGTCTCCAGGAAGCATTAAAGTGCCTTAAAATACCACACGGAACA TAAACCCAGGGCCCTCTCATCTGGGATCTCAACACCCTCTCTAAGTCTGTCAGCCTACTCTGTTCTTGGTGCCAGAGTTCTCCTGAGTTCAGTTGGA TAAAGGGCAGCACACAGCACACAGGCTTAGGTGTGCCATGTGTTAACTCCATGGCAGTGTTAGGGGCTTCTGGCCAGAGCCTAGGGTAGGGGTTGGC CACTGATGGAGGTGGAGAGACTCTCCAAAGAGATGCTGATGTGGGAGTCCTACAAGGGGCGGGGGCGGGGTGGGTGGGTTGGCCTCTGATACTAGGA CATGTTAGGGGGAGAGGAGTGCCCTTGTCACAGAAAAAGAAGAAAGCCAGTGTTTTTTTGTTTGTTTGTTTGTTTGTTTTTTAACCATCCCAAGTCA GCTTTGTGTAGTATTAATGTCTAATGATAAGGACTCCCTGTGAGATAGCTAAGTCCCATTCTCACACCACAATTGAGGGTACATTCAGGGAGCAGCT ACCTCCACTGGCCTTCATTTCTTCTTCCAAAGGACCCCTTCCAAATTACCCTGGGGACCTGCCGCTGCTGTTGGAGGATCACTGGAAAAAGGGGACA CCTGACATCTTCAGGTCTGGCAGACCTAGACCTAGAAAGGATACCTGTTCTGGGTGGAAGGCCTTGGGGTATCACAGGTCCACTCCCAGAGATGCCA ATCTGTATCCCATAAGCCAGTCTGCTGACTGTCTCTAGGGCCTGCAAGTCCTCCCAGGTGACTCAGGGGTGCCTTGAGCCTCTAAGTGGAGCACACT TGATCCCCAGGTAAGCTCCGAAATTGCACAGTAGATTAAGGGAATTCACTCACAAGGATGCCTCCTTAGCTGAGATCCCCAAAGATCCAGGCTGCAT AGGACCTGAAGGCTCACTCACTTCTGCTTTCCAGTCAGCAGCAATGTAGCAATGTAGGAGCCAGGCAGCACAGGGAAGGCTCTGAGCTCTGGGACAG ACACCTGCATCTCTTTGGGTGCTTGGATCCCCCTTCTCTTTGGCCTTTCTGCAGGCCACAGGCTTCGACTTCTGAGTCTTCACTTAGGATGATGAGG CCTACCTGCATGAATAGCGTCGTGTCTAATTTTTGTCTCCGCCAACCCCTCCATGATCCTCCTACTTCCAAGGCCACCTGCTGTCTGGTCTCCTAGC TGTCTCCAGGAAACTCACCCGAAATCGTTCGAGAGGCTCCTAGAGTTGTTAAGGGAGACCCTTAAAAGCTCCCTTCTCCTGGTCAGAGACCTTGGAG TCTCCCGTTCCTTCTGGTGTTCTTCTGAGAATCTCTGCTTCAGGTCCCTTGACCTTCGCACCTGATGCCTCCCTGCTTTGCCCACAGTGGTTTTTCT CCCTCCATTCCTACATTAGGCTAGGTTGGTTCTGAGCCCCCACCCCCATCCCGCAGTTCCCAGAGGGAACAGTCCCAGCAAAAATACATGGAACTCA GTGCCTGAGTGGGAGATTTGCCCCTCCCTCCTCACGACAGACTGGCAGCCGAGTGAGGGCGGGTGGGGGTCTAGCGGCCAAATTCTTTGTCTTCGAG GTGCCTCAGCAGGGGTCCGGTGGAGCAGCGCAGAATACACACAGCCGCTGACCGATAACTCCTGGAGAGAGCGCACTTCAAAAGGAACCTCCCGGCA GCTACTGAGGTGGGGGTGGGGGTCCCCATCTCGGGTCTGAAGTCCCTGTCAGTCACACACAGCACGCAGGCTTCCACGTGCCACATCTTTTGCTGCA GGTCCTGGGTCCCAGATGCCTTCCCCTCCCTCAACCAGGAGACCACCCTTCCTGTCCAGGGCGAGCCTCATATCCACCCTCATTAGCTGGTTTCAGA GTAAAAATAATCCTTTCCCGCCATGTGCAGCCTACCCTGATGTTGGGTGCCTATCAAGAGAGAAGATGTGTCTAGGAGATTCTCGTGGCAAAGGGGC TCCCTCACTGCCTGGGCAGGGTCCATTCCTGCGTTGCCACCCGCAGGCAGGAGGAAGAAAATTAAGCCTGTGTTGAAGGAAGGACACCTGGCAAGAG AGACGAAAGGACTCCGGAATCCCCTCCTCTGGGGAACTTTCAAGTGGGGGGGAAATCCCCACGCAGGCTTCTACTCTGCGGCAGCAACATGCGCGGC CACTCCCCGCTTCTGGTCCCCTCCTCCTTTCCTTCTTGCACCTTTGCCTGTTTGTTTCCTACCCTCAGAACAGCACCTGGGGCTGCCTCGGGCTCTG GTTTGCCTGTAAGAGGCACCTGCATACACACAGCCCTTCTAGGGACGACCAGTTTTAGCCACACCAGGACAGCTTCCCACGTATCTCGCAGGCAGCC AACATCTCACCCAAAGCCACCAAGAGCCTTTGCCCCCGCTCTCTTGGGCTGGCACCTGTGGAATCTTAAGGATCTAAATGACCCCAAGAAGCCCTCC AGATTAGCTCTTGCCTCCACACCATAGCGGTGTGTTGGAGGCCAGAGAAAGCAACGTCCCTGTTTTCAGAAACACTAATTTTGGACTGCCCCCCCCC CCGCCCCACGCTCTGATGCAGGACTAGAGATTTAATCCGCATAGATGTTCAGCGGCCTATGGGGAGCCCCCATGGGATGAGCAGCAATCAAGATCTC AGCTAAAGGCTACCTAGTAACCCAAAAGCCTGTGAAGCAAGCTCCTTGACAGAAGCCTCAGCCCCGGGGCTTTGCATTCCCCGATAGTGGCCAACCC CCTCCTACTGCCCTCCCAGGTGAATCAGAAACGGGGCCTCAGAATCAGCCGTGCCCCTTGGGGAGGAATCTTCTGGGAATGCCCGGCCCCCGGGGGC ATTTCTAGGGGTGCTTATCTCAGTACCATCTACCAGCTCCACTAGTCTTCAGCAGGTGGGGGATTGCCTGCTGTTCCTTAGCCCTCCCCACTTCTCC CCTTCCCCTTTCAACCCCCACCTCTTCCTCTGTCTGGGCGTTCACCCCACCCCCGCCCCTGTTTTCCGTCTCAGTGTCTCTATCCACTTGTCTCTCT CTATCTCCCCTTCCTCCCCTCTTTCATCTCTCCCTCTACCCCCCTCCAGCCGAGGATCGGGCTAGGAACTCGCAGAAGCTGTGACAAGCCCAGGCGG CTCTCTCGACCCTTGGTGCCCCCAGGGGCCAGTTCCTTGCTCTCCTTACACCAGCAGAAGCCATGTGCCGAGAACAGACCAGCAGGGGCAGTGGATC CGAGCTGTGGGCACCAGCCTGCCGGATCAAAGGCTAGGAATGTCTGCTCCCCGTAGGACTTCCCTCAGTCCCATCCACCCCTAACAGCAAGAAAGCC CGCCATTCCTGGGTAGGCAGGTTTGGGTGGGCTCCCTCTCTTCACCGTCTACACAGTTAAGTCCCACCATGGCTTCTCCTTTGGCTTGCTTTCTAGG TCCCAAGCCAGGAGCATTTCAAGGGCTGAATGTCTTCTGTGTCCGGGTAGAGAGGCTGAGGTACCTAGGTAAGGGGACTGAATCCTAACAATCTAGG TATGATTGGGCTCAGACTTAACTCCCAAACTGTGGAGAACTGGTAAGAAGAGTGCCCCTTGGAGGCCTGAACAGTTCCCCTTGTATAAGAGCTTCAG TAGGTCGTAGGGTGAATCTGGTGTCTGCACGGGACAACGCTTAAACACCAATCGCCAGGTTTTAGTTTCTCATCCGTAGAAGGGTCGGGAATATAGG TCAGAGACCTGGACATAGGGGAGGTAGATGTTCCTGAAGAGCCCTCGCCCCCAACCACTAATAGACAGAGCTATACCGTGTTTCACTAGTCCCAAAT GCTTCCATCCTAAGATCCAAGAAACTGCAGGTACTGCTGAGGTCCGGCCAGCACGCCTGCAGGAGGAGAAAGTGACCGAATCCTCCCGCAGGAAATG CAAACGGCGGCTGGTGTCAGTTGCAGGAAATGCAAAGGCTGCAGGAGGTCGCGATACCAATCTGACTCTTGACAAAAGACTCAAATGACACTAGCTC TGTCGCCCGGCGCCGCCGGCTGGCAGACCTTCAGAGCCTCAGCGGACTCTCCCGCGCGCCCCTCGGACACCCTGGAAGCGACCTGCGGCCGGGTGGC AGGGGCCGCCAGCTCGCGAGCCCGAAAAGGCTGGAGACTGGGAGGGGTTGCATTTTCCTAGCCCCTGATCCCAGTCGCGCGATCTGGAAACAACCCC TTTGCTTTCTAGTCTCGATTCCTTACGGGCCCAAGTGCCAAGGGATCACAGAAAAGGGAGCCACCCATCAATGCCCAAGCCGACCCCTTCACCACGT GAACGCCGGGTCAAAGCTCCAGCTCCCTAAACCTGGCTCGCGTGGACTGGGAAGGGGGTGTCCCAGGCCAGCAGAGAATCCAGCGTGCCGGGTCCTC CCGAGGCCTCCGTGCGCCCGGGGCGCAGGCTTTGCCCAAGTTTGCCGGGAGATGCCCTTCCCAGAGCCGGAGTTGTGGGCCGGGCGGGAGGGGCCCG TGATTGACAGGCTGAACTACAGACTCATCTCTTACCTTAGGCCGCGGGCGCTGATTGGCTGCTCGCTGACATCCTCAAACCCGGCTGCTCGGCGCTG GGCTCCGGAGGGGGGCGGCTGCGGGTGGAGGTGCGCCTCTGACAAGCCCGAAAGTCATTTCCAACCTCAAGTGGACTTTGTTCCAACTATTGGGGGC GTCGCTCCCCCTCTTCATGATCGCCGGCAAACTTCCTCCTCGGCGCTGCTTCTAATGGAGCCCCACCTGCTCGGGCTGCTACTCGGCCTCCTGCTCA GTGGCACCAGGGTCCTCGCTGGCTACCCAATTTGGTGGTAAGACTTGCCTCTTGTCTGCCTGCGGCCCCGATCTCTCGGCCGCACCCGGGGACGGTG GGAGGCGCTGGCCGGGTCTGGGCTGCAGCAGGCCTGGGGCTCTTTTCTCCTTGCTTCCCGCTAGCCCCCCAGCCGTCCACCCCTCTTGGATCTTCTG CTGGTGTCGCCTTCCGAATCCAACTCCTGGCTTCTCAGATAATCACCATTTTCCCTGCTACCCGCCGCAGAGGCGGGAGGGCTCTCCCTACCCCTGA AGGTCTCTCGTTCTTAGTCTTCACCCTCTCCCACCCCAATTTGGGGGTCCCGAAGAACCTTCGTTTGCTCACACTTGCATTTCTGTGCTGTCCCCGC GGCCCGGCCACTCCTCTTCTCCATTTTAGGGTCTCCGTGGGTAAAATTATCCTGTCCTTTTTCGCCACCGCACCTCGTCGGTGTCTCGGTCAAGAGA TTTCCCCCACAATACTCGCGTTTGCCTTCATATTTGAGACCTTAAGGGCTTTGGGAATCCCAAGCAGGGGACTTAGGGGGTATTTCAGTAGATTCTC CCCACTCCGTTCTAGATTAATTTTGAGCCTCTGAAGTGACTATAGAATTTGCTGATCCTAGATGCCATTGCTGATCCGGGTGTATTCGTTCCTTGCT TGTCCATCCCGGAGAAAAGCGAGGTGGGGGCTCTTTGAAAATGTACTTGTTTGGGAGGGGTAGGCTTGCTGGGTTTTTTTGAGCGAAAACCTAGTTC TCCATGTCAAATTCGTTGGTTTTGGAAGACGGGGAAGCTAGGAGAAAGGGCGAGGGAAGGGGGAATGCTGTCCCTGAGATATACGGATACAAAAGGC ATTTTAGTAAATAAGGCTGGGCGAGCAGGCGGAGTACTTGGAGCTGATGGGTGTGTGAAGGGATTCACTGGAAGATAAACCGCCTTTTGGAAGCCCC CCAGCCCTCTCAGTCTCCAGCCCCCTGCATTCCGGAAAACTTTTATAAAAGAACCCTCCCCTCCTGGGCAGTGGCTAGAGCCCTGGGGGGGGTGGGA GGTGAGGAGGAGGAGGAATTTGGGACCTCTGAGTAAGAAGGAGACTGGCCCCTGGGGTGAAAGTTAGAAGTGCTACCAGGGTAAAGTGCTGCCTACA TGGCCCCCTCCCTGCCTGCTACCTGCAAGCCTGCAGTATGAGGCTCAGAGCTTATAAAATACTGGGCCACACCCCAAGCCTTTTTCCAGATGCTTTG GGGTGTCTGAAGGCCAGGGGAGGGGGCAGTCATGAACCCAGGCACCCAAGCCATGGCCTGCCCAAGGTTCTGTTTAGAGGGTCCAGGAGTTGCTCCT TAGGTTGATAAATACGCCAAGGACAGACCATCTTTCTTTCCTGTGGACTTGGGCTGGTCTGGGGCTCCTGTGTGGAGTCTATAGAGCCTGTGCATGC TGGGGACAGCCAGGGATTCCACAGTGAGGTTCTGCCAATTGGTGAAAGGTTGCCTCTGCCTCCGGACTTTCCTTCCCCCAGCCAAGGCCAAACTCTG CCTTCTCAGAGACCCTGCGGTGGCGGGTGCATAGGAAGAGAGGGTGCCTGGAGGCCTAGGGATGGCATAGAGGAAAAAGGAGAGAGTGGGCTTGCTA GTTTTGTGTGAAACCTTTTGGTGTGTGCCTAGGGGATCTGCGGCCCACAGCAGGGTATGCTGTATCTGCATACAAGTATCAGCAAGTGGCTGGTTCT AGGTAAGGTCCCCATCCGACAAGAAATATTAGGAAAACCTGGAGGGCAGAGACAGGTCCTAACATAACATACATGGCCTGTTTGGGGGTTAAGGGGG GACCAGATGGCTGCTTTTGTCTGAGCCATAGAGAGTATGTATGGGTATTTTTGAGATGGGTGGTTTGTCAGTGCCTGTGGCTACGACCTCTGTGTGT GTAATACAGTGTGTGCTCTAGGTCAGTGACCCTAAGTGTCTGTGTACCTGTATGTCTCTGTGGGTAGAAGCTGTTAGTGCCTGAGACCCAGGCAAGT GTTTTGTGTGAAACCTTTTGGTGTGTGCCTAGGGGATCTGCGGCCCACAGCAGGGTATGCTGTATCTGCATACAAGTATCAGCAAGTGGCTGGTTCT GTGATGTGACACAGAAGTCGAGAAGTATCCGTTGCTTGTGTAAAGGGGGACCTCCTGGCTTTTGCCTGTGATACTGGACATGGCAGTATTTGTGTTT GGACTTGTGTGCTGTCTGTGCATGTGTCTGTGTGTGTCCCTTCACCCGCGCATGCCTTCCTGACAGCGTAAGGGGGAGGCCCAACAAATGTCTTTGT GCGTGACATCGGTGTTCGTGGCATGACCAGCCATGGTTGGAAGTATGAGAGTGAGCCTGGGAGGCCTGGCTGAGGGCTGTGTCCGGGCCCAGCTTCT GATCGTGACCCCAAATGCCAGTGACATAGTTTTGTGCCAGTGGTTATGCGTCTGTGGTCATGTTTGCTGACACCTGACTTGTGGGTGTGAAGAATAC CTGAAAGGGGTGCTTGGTGGCCATCAGTGGCCCTGAGGGGAAAGACAGGCAGGAAGTGGAGGTCTCAGAAGGTGGCTGCAGACACAATCGGTCTGGG ATCCCAGCTGGGGTGGGGGCAGGGCCTTCCTTGACACCATCAAGCCTTGCTTGCTTGAGGACTGTGGCTACGAGCCTTCCCTCCTCTAAGGTCATTT CCCTTTCGTGTTGGAGCTGGGGCATGAATCACCTTCATGGGGCTGGAAGTAGAGAGTGGGTAGGCCTCAAATTCTTGATTCCCCTCCTCTGCCCCAA GGCCGGCAGATTCCAGGCGTTTGAGTCCGTGACTGCCTGCCACCTCTTTGGCCCACCCGGCTCTCACGTTCACCCAGAGGATTTACAGGGGAAATGG CTTAGCTGGGATTTCTGTCCACATCACCTTCAGAAAGGACCCCTACTCCCAGTAGCCGATCCCTGCTTTTCCTTGCAAGGGCCCCAACTCTGAGACA AGGTGATGAGGAAGGGGCTCTGAGGGGCCTCTTACTCTAAAAGGAAGCCCTGTGCTCCAGAGCCTCCCAGCCTGGCAGTGGCTCCATTGGAGCAGGA CCAGTGACAACCAGCCTGCTTTCTAGAACTCTCCTTCATAGTACTAGTTAGCTCCTAGTAAAGAAATCTGTCTTTCTGTTTCTTGAGGAATAAGATC GTTCTACGGCCTTGCCCTGTGCCATCTGTGCTCCATTGGAAGTGCCCTGAAAAAGGAGGCCTGGTTGGCTGGGTGGTGTTTGGCAGCTCACTTCACA CTGTGTGGCTGAGGACTGGTGATTCCTCCCCACCCCCCCTTTTGGGGGTCACTTTTCTCACTTTTTACCCAACCTTGCAGTTTAGAGGGGAAATGTT TTGCTGAGGGCTCCAAGCCTGTTAGGGCGCCTGGGTTCTCATTGCACGACTCCAGAGCCCATCCTCCACCCAAGCACCTATCTTAAGCCCTGCCTCA GTTTCTCTATGTGTCACATCCTGCTGCCTCCCCTGCTCAACGCCCACCCAACAGCCTTCTCTCCGAGGCTTGGGAACTAAGGAACGTGTTCAGTCAA ACCCCCGTGGGGGTCAGTGGGCTGGGCCCAGGGAGGCACCTGGAGACTGTGGGGGAGGAAGGCCCCAGGCCAGGTGTTAACACTTGTAACAGGCAGG AATTAGAGCTGGCTGGGGCTAGGGCTGGTGAGCCGAGCTGGCTGGAGGCTGTTGATCCCACAGACAGTCAGTCAGTCAGACAGACAGACAGACAGAC AGACAGACAGATGGGAGATACCAGATCGGATGGCCAAGCTTTAGCAGGGTGGTCGCTCTTCCAGAGAAGATCTTGCCGTGGGGGAATTCGTCTGGGG GGAAAAAAGAATGATGGGCCCCTTGAAAATGAGTTCACAGCCCACCCCTATTGTGGGCGGGGCCTTGTGCTACAAAGGGATCGCAATTTGGTGGTTG GTGGTAGAAGGTTGGTATCCTTCTAATGGCATCACACATTGCCACACAAACAACAAACAAGACAACTGGTGAAACACCAGCTAGTATCAGGAACTGT GTGTGTCCTTTAGAAAAGCGGACTGGACTTTATAGGGAAGAAGGCACGTGGTTGGGGTTGGGATAGTGGTTGAGGGGGGACACAGCTGTCAGAGGAA AGTCCTCCCCTGCCCCCTCCCCCCTTACAATCTCCAAGTGTCTTATTAACAGCTTTGGGACCAAGAGGTAAAAGCTGGGTGTGGCCCACTTCTTAAC ATAGATTCTGAGGTCTTGGAGTTTTGGATGTCTAAACTGCATTGAATCCTGGTGTCAGAAGAGGTGACCTGGGAGCCTAGGCCTTCACAAAGCTGGT ACCTGCTGCTGCTACCCCACTGTAAACTCAGCTAGAGCTCTCTTGGGCCCACGCTCACTCACTTCTGGGCCTCTGCTCCAACCTCCATTAAAGAGTC AAAACGAGGGCCCCAGGTAAGAGTCCCCAAGGGACAGACTGGTCCAAGGAAGATTTCCCCACCCTCTCAGGGCAGAACTCACTGCTCACAGGAGGAC ACAGTTGCCTGGAAGGTTAGAGCAGTATTCATGGGCCTCCTACCAAAACCGCGAAGAGAAGGCCATACCCTACATTTACCCAGCATCCCCCTGTTTT GTTTTGTTTTGTTTTGTTTTGPTTTGTTTTGTTTTGTTTTGTTGAGATAGGATTTCTTCATGTAGCCTTGGCTGTCCTAGAACTTATTCTGTAGACC TGACTGGCCTTGAACTCAGAGATCCTTCTTCCTGCTTCTGCCTCCTGGGTGCCGGGATCAAAGGCACCTGGCCAGCACCCTTCTTGAAGGCTCGGCC ACCACATGTTCTGTTTCTATATATTCCCTCTGGGGAGAAATGTTTCAGCCTGGAAGTGGAGAGCCACGTCTGAGTTCTGAGCTTACCATCCATTGGC TGTGTGACCTAGGGTGACTCTGTCCTTCTTCAGCTCCCTGCCTCTCTCTTGACTATACTGAGAGGTGTCCATTCATCTTCTTAGAGCCTCGGGGATA TGATGGGGACTCCACAGCAGATACTTGGGACCTGCCTGAATCAGCACACCCCTTGATTTCTGTGGCTTGGTGTACCTGCCCTAAGCCCCACTTTCCA CCCAACACTGCCATGCCTTCTTAATTCACTTCCAAACCTCACGTAAGGGCTCTCTATTCCTCTGTCTCTGGGCTGCTGGCAAAGTGACCTCTCCCCG TCTCAGTTTCCCCATAGGAAAAATAAAGTTATGGCCGCTACCCCATGAACATCAGTGATCAAATTCAGGCCCCAGAATGCTGCCGGAATGCAGGAAG TACAGTTCAATGTTTGAACCTCGGTCTGGCCCTGAATCCAGACTTGTCTCTTCAAATAAACCCTCCGAGATTGGCCCCCATGGCTCTCATTTCTTCT TGTTCCATGTGCTTGGCACTGGTGCCCACAGGCTTGTAACTTCCTTCAAAATCAGAAGTTCAGCTTTTTAAAATATTTTTTATTATATTCATGTTAG TGGTTTCCTACATGTATGCCTATGCAAGAGAGTCGGATCCCCTGGAATTAAAATTATAGACAGTTGTGAGCTGCCATGTGGGTGCTGGGAATTGAAC CGTGAACCTCTGAAAGGACCAGTGCTCTTCACCACTGAGCCATCTCTCCAGCCCATTGAAGTTCAGCTTTTTTTTTTTTTTTTTTTTTTTTTTGCTG CCTAGGGGAGGTAGGGTAAGGTGGACAGAGGTGGTCTGGGGTCTCCCCTAATCCTCCTGATACCCCACAGTCTTCTGAGCTCGGAAACCTCTGTCCT CTCCAGCTGGAACACAGAGCTCCCGGGCCTGGTGGGGAGGGGTAGGCTTGGGGCCCTGGCTGCTGCAGCAGCCCCAGCACGAGGTGAAGTTGCTTCT GGAGCTGGGGGATGACTCAGAGGGTGATTTATAGACGGAAAGCAGAAAGCTTGGCTCCTGGCAGAAGCCTGCTGCTTAATTACATTCTTTGGGGGGT GGAGGTATGTGGGGCGACAGCAAGGGAGAGACTTCTACCTCGTCCCCTCCGGGCCTGGTACCTGTGATGTCCTAGCACCATTTAGGGTTCTTCTTAG AGAGTGCGTCCCCTGTACTGAATGCACGGTTAGCCACTGAGAAGAGGAAGAAGTGGGACAGAATCATCGGAAGGACAGAGTCCCGTGGGGACCACCC CAGGGACAGGCTGATGGGGCACACAGGAAGAGTGGGATGCTGAGAAGGATCGCTGAACCTCCACCCTGCTTCTGCCGAAGAATCCCTAAGCCACCTG GGCCTCTGGGTAGCCACTCTCCACTTCCCCTTCGCGTGGTTGCCTGTGAAGACCTTCAAGTTGGCTTCTTGTCCTGTGGCTTGGGTCCTGGTATCCC ATGCGTGCAGGAGACCAGGCCTGGAACTCAGAGACTAAACTCTGCGTCTTTGGGTTAGATGACCTGTTGCGTGGAAGTGTGATGACTGCTGCAAAAC TGCAGCGGTTCTGGTAGCATCAGCCTCGTGCTGGAGGGAAGGAACCCCACTAACCCTGCCTTTAAACTAACTACAGCTAGCCTGTCTGCCCATGCTG ACCAGTGTAGTGACTCCAACACAGCCCCAGATACTGAATTTCTGGGTCAGGGGTCCCAAAAGGTATAGGACAGGCAGGGGTAAGGAGGCCAAGGTCT GCAGCACCTGGCTGCCTGTTTGAGCTTGGTTAGTACAGCTGGCAGGACTTGGCAGGGGTCAGGATGGGGACAGCAGACAGCTCTCCAGTTCCCCGTG AGGCAGGCCTTCTCAAAATGGCCTCATTAATGCATGTGGAGTGAATTCCAGAAATGTCAGGTATACTCACACATCTAAAGAAGGATGGGGACCCAGA AATGTTCTGTGCTTGGAGACAAGAGGAGTCAGAGTGAGGGATGGTTTCCAGGTCCGGGATCTGAACTGTTGGACATGGTCTTCCTATTGCAAAGTGA TGCTCTGTGCTCAGGACAGTGGATGTTTGAGTTTTCTGTGCCTAGTGGGAGACTGGAACTGATTCCGGGACAGAGTAGAGACCATAAACTTTATATG TGAGCAGCTTTGAGGTGCAAGCTGAATTGCCAACCTTCCCAGACCTCAGTTTTCTCATCCACCAAATGGCCAATAACATGCCTTCCCTGCCCATGGT ACTAATGAGAGCTCAGGATGTCTGTCTTACCAGAGTCAGCTCAGCAACTACCATTGTTAGAAAGAAGACCAAGATCCCCACCCCCTACCCAGAGGAG GTGCAAGAGTATCTGTAGTGGATCCCCAATCTCTGAGTAGAATCTCTGGGAGCAGAGCCGTTGCTTGGGTTTAAGACCCAGTGATGGCAGGTGTGCT CCAGTTTCAGCTCTGGAGGTCCACGAAGAGCACATAGGCCTGATCCCCACTGAGACCCGGTTAGGAGGTCTGGGTGGAGGTGAGGGCAAGGTAGGCA GCTGGAAGCACTCTCTCAAAGCCCGAGGCCATCAGGAAATCCAAACACCCCCAGGGAATGCCAAGGAAACCCACAGCGGCATAGCCCTGTTCCCTAA CTGAGCTAGAGAGACTTGAAGAGAATGTCCTGTGTCCCTGTGTTGGCAAGGGGGATGGGAGCAACAGGACCCTGTGACCAGGTTTGTTGGGAGGGCC TTTCTGCCAAACCTGCCCCTGGGCGCAGAGTCCCACTTATCTATCGGAGCCAGCCGGGATCAGCAAGGAAAACCAATCTTCCAGAGCCCGCTATGCA TGCAAATGGGGGCTTGTGACCATGTGAACCTGCACACCGCCTCTCTCTAGTTCCTCCACACTTCATAACGTGGCTTTCCGAGGGTGTCATTCTGTCC CTCTGAAACCTCTCATGGTTCTGATCTAGACCCCCTTTGTTTTATTTTGGCCTCTACCTGCCTATACAACATGCCTTTCAGAACCCCTCTCCCACTC CTTCCTCAAACCGAACACAAAATAGTACATGAACCTCTGCATGCCTCCTTCCTCTGACCTGGGGAAGGCAGTAGGACTTGACCCCTAGGTTGACCAG GGCTTATTTCTGCTCTGCCAAGCACAGGACCTGGCTGGCTTGTGGCATGGAGCTGACAACCCTAAACTGTGAAGGGCCTTTGGTGTCTCTAAGGCAA TGGGACCCTCCTGAGCAGACTGCCGCAGCCGTGCTGGATACTGGGATGTCTCCACCATGTCCATTCCCTTGGGCTTTGTTGCTCCTCCTCAGCCCAG ATTGAAGAATTCTATGTATGTGTTAGAGCTTCTTCTATGCTCACCCAGCTCTTGCTATGCATATAAAAGTGTCAGGACCTAGGGACAGGTGCCTTTG CATGCTGTGTGGCTGTCTTTAGAGACCTAGAAGATATTCTTCCAAGACTAACGGTGAGCAGCTGCTTTGCACAGACCACACGTGGTGGGAGAAGGGT TGGAGCCCACATTCTGCCTCCACTCGGGGTCAGGAGAAGACTTCCTAGTTAGAAGGAGGAGAAGCTGCTTGTCTNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNTGTGTGTGTGTGTGTGTGTTGGGGAGAAGCTATGTATGCATTTGTGGGAAGGGGGTAGCTTATTCATGTGTGCATTTGAGCATG GAGCCAGAATACAACCTATGGTTTCATATCTTGGGCACTCTGTTTAGCTTTGGAAACATAGTCTCTCACTGAGACATTAGGTTCCCTGATTCGTCTA GGTTGGTTGGCTAGTGAGCCTCAAGGATTTCCCTGCTTCTGCCTCCCTAGCTTTGGGATTACAGGCACACCACCACACCCAACCTTTTCCCATGGGT TCTGAGGAATGAGCTCAGCAATTAGATAAGCCATCTTCCCTCCCTAGCCTCAGAATTCATGCCCATAGCCTAGCCCTGAGTTGGTGTTTCTGGGCTG TTGAGTCTTTCCTTGACTTTCACAGCTAAGACATTCAGCACTATTTCCTGCTGAGAAGCCAGAATGCTCTCTCCTTTCTTATAAAGCATATTCCTTT ATGCATCAGCCATTTAGGAACCCCAGAGCTAGACTTGATACTCGATGTTTGCACCTGTGCTGACCTTGGGTGACACATTCGTCTTCTCCTTTGCCTG ATCCAGTGTTTTCATCTCCATTCTGCCATTTATCCAGAAACATTTTGTATTCTAAACTCCTTGCGGGCAGACCCCATGCCTGGAGCATCTAGAGTTC ACCACGCTTGGTCTCTGTGTAGCGGCTACTGATGCTCCATAAATATGTTTTGGCCGTCAGACAGGACGTTGGCTGCCAGCTGTGCTGAGTTCTTTCT GAAAAGAGGCAAGGCAGAGGAAAATGAGAACGAAAAATTCATTTTGTCAGCATGGCAGCAGTATGCCTGTGATCCCTGCACTCCAGAGACTGAGGCA GGAGGATTGCAAGTTTGAAACCAGCTTGGGCTCTACAATGAGAGTCTGTCGACACAAAAGAAAGAAAGAGGGAAAGGGGTGGGTAGGGGAGAAAAAA ATGGCTGTTTCTGAGAAGCGGCTCTGAGCTGACAGTTTTGAGTTGGGGGAAGCGCATCCTGTATCTTCCCCAGAAACCTTATCTCTAGGGATGCTGT TTGCAGGACTGACGGTGCTTTAGTCTAAGCTTGAAGGTGTCATCCCACCTCTTGGGAATCTCAAACATTGTAGCCAAGGATGACCTTGACCTTTTCC TCCTCTTTCACTGCCCCAGTGCTGGGCTTAGCCCGCACCACTGTGCCTGGGTTTATTTGGTGTTAGGGATTGAACCCAGGGCTTCATGCATGCTAGG CAAGCACTCTACCAACGGAGCTATGCCTCAGGTTGGGGACTTTGTGTCTCCCATGGCTGTGCCTTCTCTTTGTTTGCTCCCCCCACCCCATGCCTGT CTGTGGTGTTCTCCTTGGGAGATGACTAATTGATGCTCTTGATACCACTTCCTAGGTGAGACACAAGTACCCAAGTGCCCCCTTTCCATCTCCCCAG CAGCTATTGCAGAACTTCCACCCTGTAAAAATTCAGGGCGGCATGCGGATGAGAGAGAGAGAACACAGGAGACCACACTCAGGACCACATAGGGTGG CTGGCCTCTCTCAGGCCAGACGTTCCCATTGGCAAAGCTGTGGGGAAGACCCCAAGTAGACCTGGACTAAGCCACATCACTGCTGTGGCAGGAACCT CACAAAAAGGAGAGGAGAACACTCAATCGTGeATTGTGGTGCCTTTGACCCCAACACTTAGGAGGCCAAGACAGGTAGATTTCTATACCTTCAAGAT CAGCCTGTCCTATGCGGGAAGTTTCGGGACAGTCAGGGTGATGAGAGACCCTGTCTCAATAAACAAAAATAGAAGTAGAGAGGAGCTTCAGGGTAGG GGAGCACAGCCCGCCAACCACCTGGCAAGGCTTCAGTTCACCTCTATGCTCCTGCCCTTAGTTGGCCCTAGACCCATCCCAGTCCCTTGACTTCAGC CAAAAGAGCATCCAAATCTACTGTAGGTGGACCTCCATAAGGTCCAGAACTTTCCAAGGATGACCATGACTCTGGCATGCCTTTGAAGCTAAAGCTG CACCCTGTCTCCAGAAAGTGGGCAGGCAGGGAGCAGATTTTAATCATCAGCGAGGAATCCATCTGTCCTTTTTGAGGTTCCTGCCTCAGCCTGGTGT GCACAGAGGGAACACATCACCTCTGTCAGCCTTAGAAGCATGCTCTTGTTCTCCCCATTCTACAGGTGACAAACTGAGCCCTTGAGAGAACCACTTC AGGGCCTAAGGCTCCTCAGGCTGTGGACTGAAACTCCAATTAGATGCTGACTGTAGGAAGCCAGGCCCTCCAGGGTTCACAGCCCCTCACTGATAGC CAGGAAGCTCCCTCAAGGTCTATCTAGACTTAGTCCAAGCCCAGACAATTTCATTTGGTCTCTGGGATGTGAACATCACTGAAGGGTCTCAATCTGC CCTTGTGATTGGATATGTTGTTCCTGGAGTCCAGGGCAGTCCTTTGGAGGTAACCTGAAAGTGCCATTAGCCCAAGTTATGAGGGGGGTCCTGCCCA GGTCTTTGGGGCAGAGGGCTCTGCACCACTGTCTGACAATTGTGCCCCTTTCTCTGGGGACAGGAATCTGAAATCCCAGGGCCAACACCCCTAGGGC CCACACCCACCCTGGTGATGCTCCAGGCATCCCAATATCTGGGGAATCCTTCCCAGATGACTGTAGGCCTCCTGAGCTCTCTGGGTTTCTACCTAAA GTCTGTTCTATTAGAGAAGATGACAGTACTGATGACCCAAAAAGAGGTCAGGGCAGGGTATTTGCAGGGGCTGTGGGTACCTGGAGGGTTAGCTAGG TGTCCAGCATGGTGAGCCCTGTAGAGGCTGAGGGCTATTTCTGCCCATGTCACCATTTTCTAGAATGAACTCCTTGGAAAGACTGATTTTGCTTACT ATTTAAATTTTGTATTAGTAACACACACACATATACACACTTTCTGGAAGCACATGGCAAGACTAAATCAAGAAAGCACATGTGTCCTGTGGAAGTC CAGGACAAGGATCTCAGTTTGAATGAAGAGTATTGACATTTGTTAACCTGAGGTGAGGCAGTTACGTCTCTGGTACCTGACAAACACTCAGCCTTCA TTTAATAATCTCGTCCCACACACTCTAGCCAGGATGAAGGAGTTGGATGGGGAAATGGGTCTGTCTAGGTTCTCCCAGCACAGAAATCTCGGAGAAG GCTTGACCATCTTGGTGTCCCCCGCCCCCAGCCCCCTCCAGCCTTGCAACATGGGCTCACCCTAGCAGGAGAGGAGGCCCTTGTTTAGCAGCAGTAC CAGGGACTGTCCCAGCTGTGTTCCTCTCACCTTCAGGGCCCTCTTTGCTTCAGGGCCTCATCTTGCCACTCTCGGTCTCAGAGGACCTTCCCTGTGC TTGTGGCTTTAGATGATGTGACCAGAAGGGCAGCGACTGCATCAAGGAACACACCCACCTGACTGTAGTGTTCTTTAACCCCAAGGCCGACCTTGAC CCTGCACCACCCTGCACCTTCCAGCCCCAGCCTGGCTCTCCTCCTGGCTACTCTCATCTCTAGGATGACAGTCCCGGGCTTCCATCTATGTAGCTGG GTGACCTTACTTTCTCTGAGCCTCAACTTTTCCCTCTGTAAAATGGGGATGGCAAGGATTAAAGGATGTAACATTATATGAGACAGACAAGGTCTGG CGTCTACACAGTGAGTAATGCTCCCATTTGCCATCATTAATCTCGCTGTCTATTTTGTTGTTTTCGCCATGCATCACCGCTCTGCGCTTTTGTGCTC GCCCCTGCCTTCTTCTGGGGAGGTTCCGAGGACTCCTGTCCGCTCTGTGAAGTGAGGTTGGTACCATTGTCTCACCAGCACCTGCTCCACCTGAGCT CCTCCCGGGGTCTCAGTGGGACTCCTTCAACTCTACCCACCTTGCCAGGCAGCACGGGACACCACGCAGCATCTGGGGACAGGTCTTAAGCTGAGGG GCACTGCTGTGTGTGCCCTGCTTGGCAGAGGCCCAGTCTTCCTGCTCCAGGTGTCTTCCTCCTCCCAATGTCCTCCTCCTCCTCCTCCTCAGGAAGA CTGACTGACACTTGTCATCTTTCTTGACTTCTCAGTCACATCTCATTGGTATCTATCTTATCCTTCCAAAGAGGGGACCAGCTCTTGAGGACATGAA TTCTGCTCTGTGTCTTGGTGACCCAACTGAGCTTCATATAGCAACTCTGGGGTGCAGAGCACAGCTTGGGGAGCACTGTCGTTCTAGAGATTGTTGA GCCGGTGACTCAGGACCCCTCCTCAGAAGCTCCGGTGCGGCTTTCGCTGCTTCCCGTGAACTGGATAGCAGCTCCCCCTCACCCATGATCTCAGCAG GGCCCATCCTTGAGCTTCTAGCCTTTCGTGGACACATAGCTCTCTCGCTGCATTTGAAGAAGAGCTTTCTGTGGAAATTGGCACGTCTCAGACTTGT TGGCTGGTGGCTCTCAGACTTTCAGAGCCTCCATTTCTTCTATGTAAAACGGCGGCGGGGGTGCCGTGTTGTCAGGAAAAGTTGTGAGGTCCTGCTA CATAGGGGCTGGGCTGACAGGGACTGATCATGGGTGGTATGCAGGTCATTCCAGTCCAGCGAGGGTTGTCCAGGGACTCAGTACCGGGAAAGAATGC AGGTCATCCTGCCCTAGAGAAAGGGCCACGCTTGGGGAAAGCTATACGCCTTGTGATGGTGTGCCCCAATTATCACCTTATTTGAAAACCAAAATGG GAGTGGCTCAGAGCAGGATGCAAGTTATTCAGTGAGGACCCTGGTCTGACCCTGTGTCCTGGTGTCCTGCTCAGCTCCTGGGAAGAGGTAGGCAAGT CAGATGTGGTGGCTTCAGGGAGTTTTACTGGGGCTCCTGGGCTGGCCTGTGCAGGTTTAATATGGCTGAGGCATCGGTCATTTCATCCCTGAGAAGG GTGGTGAGTAAGCCTTGCCTGGGAGGCTGGGGCCGCTGTACACATCTGTCTTTAAGGGAAGAGGGCCCTGCTGTGCTGCTTAAAGTGTCACAGACAA GAATGGGTGGCCTGTGTGTGACTGATATGCATCCTACACAGACACCAGCTGTTTCTGCTGAGAATTGGAGAATGAATATGCTTTTATTATATAGTAC TTTATGCACACAAAGCAAACACATCATCTATGGGATGTCATAACAAGATGAAACCTTGTGCTTCCCCACACCCGGAAGAACCAGAACATCAGCATCT GTCCTTAGGCTTCTCCCCTCCCCACCCCATCACCATCTCCTTCCACATGTGACCACATCCTGATTTTCGCCATTTTATAAAGAGAGATGGTGGAGGG GTGGGGGGAATGTCTCTCACCCAGTCTGGAACTCACTAATTAGGCTAGACTATCCAGAAAGTCCCTAAAGATTCTCCTGTTGACCCTTCCCCAGTGC TGGAGTGTTACCACCACACTTGTTTGCATGGCTGCTGGAAATGGAACTCAGGTCTTAGCTTACAAAGCTTACTGATGGAGCCACCTCCTCAGGCCCT GCACAGGGATTCCATGACTGAGATAAAAAGCCGGCTGGATGTATGGGCCCACACCTTTAATCCCAGCACTGCAGAGGCAGAGGCAGGTGGACCTCTG AGTTGGAGTTCCAGGACAGCCAGGGTTACACAGAGAAACACTGTCTCAAACAAACAAACAAACAAACAAACAAACAATAACAAAAGATAAAATGTAA CCTGAGATAAGAATGCCCACAATACATTTTTCACTTTGCTTGTTAAAAAAAAAAAAGAGAGAGAGATAGTTTGTGTGTGGTCTTCTGTGGTTTCCTC TTCTTTGTCTTATTTTCGAGATGGGGGGGGGGGGTCTTATGATATAGACTTAGCTGGTCTGGAATTTTAGTATGTAGACCAGGCTGGCCTCGAGCTC ACAGAGGTCTCTGCCTGCCAAGAGCTGGGATTAAAGGTGTGTGCCACCACATCTGTCTTTGTTCTTTCTATTTTTTGTTTCTAAGTTCCTCATTGTT CCTGAGTCTTTCTATATTTCCTTCATTTTCCCCACTGTAGAGTAGTCACTGTGTCTGCTTCCTTCTTTTTGTGTACACAGGAGTCTCTCTGTGCCCA TGGAGGAAAGCTCTCCCTCCATACACTTGCCTTGGAGTGGAGCAGTAGGTCCTGGCTGTTGAATGTTCTTAGAGTGATGCCTAGCCATTCCTAAACA TGCTCCTATCTCCTTCCTCTCTTTCCTCTCTTTCCTCTCTTCCCTCTCTTTGCCCATGATCTTCCAAAGCTTTTTCAAACTCAGAGCCCCCGTTGTC CCAGGTCTCTTACCAGCTTGGCTTCTGCCTCGCCCCCACACTGCACATCCTCCAGCTCTTCGGAGCATCATTTGGATGGAGCACTAGGTCTCAAAGT GTGTCTCATCACACTGGTCTTATGTGATCCTGCTGGGAAAGGCTTCTAGGGACAAGTAAATTTAGAAGTTAGCCTTGCTTGTTGGAATCTCAATGCC ACCAGGTACACCACAGAGGTGACCCCTTGCTTTCATTTGTCTAGTCTTTCCCCAAAATAGCTAGCCCAGGAAATCCTCCTGCCCCTTCAAAATTCAG TTTGGTTTTTATGGTCTTTATTTTCCCAACTGGGAGGCTGCGATTTTTTGCAATGTATATTTTTTTTAACATTCTGCATGAATTGAGGAAGTTTAGT CTAGTATCTCCATCGCTTGGGGGTCTCGAGATGATGAATGAAAAAGCATAAGTGGTGAATGAAGGCAGCAGTTAGAGAAGCAGTTGGCTCGTTGCTC TGTGGTCCAGCTGGGTCTCTTGTCCTGAGGAGTCAGAAGCTATGGACAACTTGAGGTTGTTTGGCCCGTGTCCAACCCTGCCTACAGTGTTTCTACC CAGCCTTCCTCCAACACCCACGTGGAATGAGTCACTCCCATTAAGCCTCCTGTCACTGGTTTGGGGGCATCTGTTTCATAGGGAGGCCTGAAACCCT TGCAAGGGCAGAGGCTCTGTTCCATTTGCCCCCTAGGTTCTCAAGAGTGGCTGCTTACCCTCTGGCTGGTGGATGAGTGCAGTCGGAGGAGGTCTCC TGTGTATCCTTGCCAGGGACTAGAGGGTACTATGACAGTCTGCAGGCTCTGGAGTCAGACCAGATGAGCCCTCATAGACCTGCCAGTCTCCACGCCT CAGCTTGGGAACTGGGCATCTTCTCTTCTTTCCACCCACAATTACTCTACTGACTCTGGGAACAGGGTCTCACTTTGTAGCTCTGGCTGGCCTGAAA CTCATTATGTAGACCAGGCTAGCCCCAACAATTATGACAACCTCCCGCCTCTGCCTCCCAAGTGTAGTCATGTTCCACTGCCCTGGCTCTTTGTTTG GTGGAGTTCTGTTTGTTTAAATTGAGACAAGGTCTCATGGAGCGTGGGCTAGCCTGGGACTCACTATACCGTGGAGGTAAACTCTGATCTTTCCTAC CTCTCTCTACAAGTTCTGGGATTAAGGGAGCACACTTAGTTAATGTGATGGTAGAGACAGAACTCAGGGTTTTGTGTGCATGAGGCATGAATTGAGC TACAGCCCCAGACTGTTTGTCTGTTTTGAGACAGGGTCTCATATGTAGCTCTGGTTGCTTGCCAAGTAAATAAGACTTGCCTTGAACTTGTGGTGAC TCCCCTGCTGCAGCATCCCAGATACTGGGATGTGCAGGTGTGCACCACCATGTGTGACATTGCTGGGTTTTATTTTGATCCTTTGTTCATCCCTACA AACTAGAACCCATAACAGTGCTTGGTTGTTTTGGGGTTGGGAATGGAGGGAGCGAACCTACAGGTAGGAACTTGGGAAGCCCAAGGGTAGCCAGGAC TTTCATGGCTGACCCAGGAAGCTCAGTATCCTGAGACCAAGATCTCTTTGACACAGCGTGGCTAGAGCGTCCTGTGCTGTAGCAGTGTCCTAGAATG GAGGGCTCACAGGGCGTGGCTTACTGCCGTGGTCCTCAGCCTCCTGCACAGGATGGTGTGCGCGTGGGATGCTTGCACAGGAACAATTTGAAATCAC TTTTCCCTGGGCTTAGAGCGCCAGGAGGTCAGATAGCAGGGCCTGAGGATGCTAGAGGCCCACTTACCATTCTCAGGCATACACCACTTGGCCTTGA AGTCGGGGGAAGCTCCTCAGACCTCATTAACCTCCTTTGTAAGGAGCCTCACCAGCTCCAGAGCACCTGCTCTCTTCTCTTCGCACTGGTCAGCCTT AGTTCTAGATCTGTCTTCCCTGGCCTCCCAACAGAAAGAGATAGATCGTGGGGCACTGCAGACAGGCTGAGGTGAACGTCTGATGTGACACAGGATG CCTGGGGACGTTCACTGGGGAGCAGAGAAACCTGGGCATTTATTTCATCCCAGGTAACGAGCTGTAGTCCCCTCCACAAGGGAGAACAGAGCAGGGG TGCTTCAGAGGGGTGGAGGCACGTAGGTGAGATTGCCAATTGGGTGTCCAAGAGGCAAAGATGTCATTGAAATGACAGAGCCAGAGAATCTAGTAGA GGGAGACTGAGATCTTTGCGGCAGAGGAAGGAAGACATTCAAAGCATTCACAGACCACTGGTCTTCTGAGAGCTCGGGTAGTGTGAGAGGGGGAAGG GGAGATGGAGGTGGTGGTAGGCTTTATCCTTTCTGCAGCGGTACAAGCTAGAACGCGTGGTAACAGGGTGGTATGAATTTCCCCAGAGGTGTGGAAG GCTCCTGTTGGTCTGATTCCTCAGCCTCCTCGTGAGACACTCCATCAGGTTGGACCTGAAAGTACTCAGATCCCTGCCAACCGCCATCTTTTCAGAC TCACAGACAGTCTCCACATTGCTGCCTGAGGGATCTGAACTCAGTAGCTGACTGTCACCCCTGTCTCTGTCCACCTTGACCCTGTGTGTTGGTGTCC TACTTACATCCCTATGTCCAAGGCTCCTTCCTTTTGAGAGCAGAGAAATGTACACAGAGCATCCCCTTTTACCTCCTTCCTTCTTGGTCCAGTCCCC ACCACTGGGAATACCCTGGATATACCTCTTTTGCCCCAGTGTGTGTAATACATCAAGGGTTACACTCGGTTTGGAAGGAAAAAATGATTTTTAAAGC AATAACAGCAACAACAATGCCAAGTGTGGTGGTATCTACCTGTCATCCCAGCATCTCGGAAACTAAGGCAGGGTAATTTCCATAAATTAGCATAGCC TGGTCTGCATAGTGAGTTCCAGGCCAGCCAGAGCTACACAGTGAGAACCTATCTTAAGGTAATATAATTTAATATAATATACCACTCCCCTATGTGT TTTGCAACCCATCCTGCCATGTGGCCCCTTTCTGTGGGTTTTCTCAGCTCTGCTTGGAAGTTGCCTGTGTCCTTGCTATTGTCCTTTAGTCCCTGTG TGCATAGCCCTGTTATTAGATTATACAGTCCTCCGGGTGAGGGGCCATGACAGCGTTGAGTTAGTGTGGGACACATTTTGGGTGCAGAATAAGTGAA TTCTGCCAGAATGAGTCATTAGCGGAGAGTGGATGGAGGCCGTTAGACACAATGGCAGCAGCATAGGAGGCGAGATGAAGCCATTCAGACCCCTGTA CCTTCTGAGTCTGCTTCTCGTTGGTGCAGTGCATTAGCCTGAACCCCTTGGAGCTTTTGAAAGAATAAATCTCAATGAGCAGGTTCTGGAAAAACAG CTTTGCAGTCTCAAAGGTGGCCAGCTCCCCTGAGAAGCCCACATCCACACTGGTTCCGAGAACCCTCACCTTCTGGGCTTGCTATCTTGGAAGAGGC CCAGTCACCTAGAATTCTCTGTGGTTATTTGAACCCATGTGTCAACCCTTCTGATTCTGGGACAGAGCTCTTTTGTCCTTGAAGGATGCCTGGGACA GAGTCCAGCACTCAGCCTGAACAACAAGACAGGCTGGGTGTCTCAGCTCTCCACTGACACACTGTAGAGTCTCCCACCCCAAGAAGTCCCTTCTTGC TTTCTTAGCAGCCTCAGTATCTCCATCACCAGCTGTATGATCCCAAACATATTACCCGGCCTCTAGAACCTGTGTCATCACCTGTCAAGTGGAGATA ATAATGTCGTTGGGTTCCTTGGCAAATTAAAGGATGTATTTCATGTAACGTGCTTTATATGATACCGGGCACAGAGTCAGGGCTCAATAAATGCTGG CCTTCACAAATAATAACCATTGTGAGTGCCCTGGAGATGGTTTCACCCCCTCCACTCCCTTACACCAGAGAACAGGAAATCATTTCCTCACGGCCTT CTTAACAACTGTCTCCCCAAATAAGTGCACCCTATATTATCTTATTCACCCTGAGTGTGCACCTGTAAAGCGGCCCCTTTATTCCATTTATAGCTGT TTCCACAAAGAGGCCCCCATTACCTCATCTCCCTCTGTTTTGTGGGCTCCTCCTGTCTGTGGCCACTCAGGGCCAGTGTGGGTTCTGAGGGAGCCTT GGCCACAGGTCTGTGTTGGCATCTGCCCTCACGCGCACACACACACCTTTGTAGAAAAGTCTATAATTTCTTCAAGCTTTGTGGCACATGCCTGTAT ATCTGTCAATTCAAAAAGACTGAGACAAAAGGATAGAAAGTTTAAATGAACTATATGTCTTTAATCCCATCACTGAAGAGGCAGAGGCAGGTGGATT TCTGTGAATTCAAGGCCAGCCTGGTCTATATTGTAAGTTTTAGATCAGCCCCGACTACATACATTCTCACCAAAGGGGGTAAGAAAATGAAAGCTCA GAGTGGGTCGGAGAGCTTAGTAGGACTATCTATCTCTATCTCTATATCCATATCTATATAATTGGAAAAGGGCTGAGGAGGAATAGCCTTGCGTTCA GTACTTGCCTAGCAGTGTGAAGTCTTGGGTTTAATCTCCAGTACTGAAAGAAAAAAAAAATCTATTGGAATTTCTTTATTTAAATGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGACAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGACTTTTGTATAC AAAGCTTGTTCTTCTCCAGAAGAAATACAACAAGACATCAGACTATAGAAGCAGAAATGCCTGAGGTATCAGCTGGGCCCTGCAGCCTCCTGGGGTG ACAAGATTGGGCACAGTGAGAGGACATGGGTGAACAGGGAGGGCTCAGCCTGCAGAATGTATCCTTTCCCCGCTGGGTTATGCACAGGAACTCAGAA AGATGTGGGTCCCTGTAAGAGGCACATCTGGAGACCTTGAACCCAAAACTTCTGTGGACAGCCAGCATGTCTGGAGCTCCTGATACTCACCAACATG TAAACCCCACAGCAAGACTCAGCAATCTGGGTGTAGAAATTAGGAGAAGGGAAAACTCTCGGAGGAAGAGAGATGCAAGGAGGAATGTGGGCAAGGG GGTGGGGTCCCCCAACAGTGCCAAAGACAAGGTTCTTTTGAAAGTTTTTTCATGGTGACCTTCCTTTTCGAATGGATGTTGAGTTTAGCAGCGGTTA GCAGTGAGGCTCTTAAACTCCAAGCTTGGAGCCGCCTGTGATTTATCCTGGCCTATGTAGATGAGGGACATGCCCAAACACTTTTTCGCTCATACTG CTGATCAAAAACAGTTTGGCTGCTGCGGCTGTCAAGATGGAGGCTTGAGAAACCTGGAGAGCTAGAATGAGGAAAACACCAGGCTTGGGAAGAAAGG AGGCTGATTCTGGGTACCAGGATGTACGGCGTAGGGCGGAGCAGATAGGGCCCAGCGCTGGAGCCCCATGAGCGCGTCCTAGTCTCCTTTGCTCTTG GCTTGCTCCTTGAAATGAAGCGAAGACCCACTGAGGCCCAGACTTCTCCATCCTATGGTGCAGACATCAGACTGTGAAATTCTGTGTGTAGCCAGCA TTGAGGCTGAGCTGCCCTTCTCTGAGTGCTAGAATACCTAGCGGGAGTCCCGCTAGCAGCTAGGAGTGTGGAGTGGGCACTCACAAACCCAGAGAAG AAAGGCTAGGCTTGGTGGAGAAACTGGAAGCAGGAGCCCAAGACTGGTGGATGTGACCGTGTGGGTGCGGGGGCAGGGGGTGCGAGGAAGGTGTTGA GGCTCGCTCCCGGGAATGGGCCCGGGAGGGAGGAGCAGGCAGCGCTTTGAACTTGCGCTCAGCCTCCAGAAGAGAGGGCGGGGAAGTCCAGGTGCCG GCCGGGCTGCTTTCACCTGCGGATCCTTGGCGCTTTGGGGGACGAGGCGCAAGGAAGACCTCCTGGGAATGCATGAAAATACCCCACCTTGAAAGGC AAGGAGCGGAGAACATAGCCCTGAGCGCCGGGTGTGGCGCTGCTCCCGCCCCCATCCCTACCCGCCTCACGCTGCAGCGCGCACTGCTGCTGGTGCT GGTACTGGTGCCAGTGCCCATTCCAGGGCCTCCCCGACCTGTTGGTGCTCCCAGCATCTGAGCCATCAAGGTTCCTGCCCACAGGTTTCATCTAGAA GTCCCCACAAATGAGTTGGGAGTTTTCTATTGTTCTTCAAACTTTTATTATGGCAATCATTAATGAAGGCTGTGGATCTTGCTTGGAGATTTAGGGC TCAGTTGGTGGAGTGCTTACCTCAGCATACCTGAGGCCATGGTTTTGATAAACCCCATCCTACTTGGATGGGGAGTCAGAAAGGTTATAGCTAGTCC TGGGTCAGTCAGCTTATTCTACATAGCAAGTTCCAGGCCAGCCAGAGCTACATAACGAAAAGTAGAGGAAATAATATAAGGAGCAAAGAGTTTACAC ACCTTATAGTGCCACCATTTAAAAATGTTTTAAACGTGCACGTTTGTGTCAAACAATTACAAAGAAAAATTCTATTCCGCATGAGCGCTGAGATTCG ATATGTAAGGCTGCCCCCACCCCATCAAACCGCCATGCTGGTTAACAAGACGTCTAAGAATTCCCGATGATTCAGGTTGCCTAGGTGTCCTCCTCTC TGCCTTTACCCAAAGGGTTTTCAACGCAGGCTCCACTCATTTCTTTTCCCTTGTCTTCATTTTAATCTCAAAGTAATTCATTCTCCTTATGCCCAAT ACACTGGCTCTTCAGAGAGCTATGGTTTGCAGTCTTTGATCATGTGACCTGTTCTCAGATCATCTGCCTGCTTCTTTAGAGTCATATGACTTGTGCT TCTGTCTCTCGTCTTCCTGACAACTGAGGGTTACTTAGGCGAACCGTCTTTGGCTGGTGAGCTTTATGGAGGAGGTTGGGTACCCCACATTGCGCCA TCTCCAGCCATCCAGCTCTCCTGCTTCTTTGGAGGTGTTTAATAGGGTTTCTGAGTCTCTTTCCCAGATGGGCTGGTCCAGCGGGTTAGGACTGGAG TCCATGTGTCTGGGTTTTGCAAATCTGCCCCTTTGCTGGCTGTTTAAGTGTCTCACCTGCCTTCCTGGCCTCAGCAGTCAGCTGGGCAGTGCTCATC CTGGGCCCTCCAAAGGGCATGGGGAGGGAGGTGTGGGAAAAGGTGAGTTCTCATGGCTCTGGCTCAGCAGATCTGAATGTCTGGATCTGGGAGTTGG TAGTTCTTATAGATTATAACCACGCCTATAAACATCTGTATGCTCTCAACATCTAGCACACAGCTGGCCCAGTGTAATTGTCCCTGAAATGAAGATC TCCACCAGGCTGGTGGCCCTCAATGAGCCCCTAGAAAGATGGTTTCTGGTGTGAGCTTCCAGCCAATAAATAGCTCAGCTTTCTGCATTTGAAGACT CAGAGAAAGACTTCCCCAGGGTGTGCAGCAGTTGTGAGAAAAGTCCAGAGAGCCAGCAGGGTGTCTTCTGCTCTCAGCTTGTCATGGCAGTAGCCTG AGTGGGGAGGAAAGACTGGGGAGGTCAGTGGGAGCCTCTGGGTCCAGTCCAAGGGGGTCCTGGGCCATTAGAAAAAGCAGACTCTCCACTTAAGTAG TCACCGGTGAGGGAGGGAAGTTGTCCTCTGAAAACCTCAACTTTTAGTGGAGAGAACGGCTCTGTAGACAGCCTCAGTAGAGAATGTTCAAGATCTA TCTTCTTCTGACAAGCTGAAGAGATGACCAGGAGGAACAGTTTCAATCCAGAGGGGATTTTTCTAACCTCAGATCTTGAGGGGTGACTAGGAGCTCA CCGTGAGATGAATGGCCAGGGAAGCTGTTTTGTCTTTCACCAGAACTTGGCTTGAAGGGAAAGCTCTATGAGAACTGGGAATGGTTCTGACCTAGGA ACCAGCTGTCTGCTTTCCCAGAACCATTAGCCAGGCCCTGCCAAGCCCTCACTTCACTGCACGTGGGAGACTGCCCTGCCGGAGAGGGTCAGCAGGG AGGAAGTGGTACGCCGCTCAAAGGAACCAATGAAGCACACTGGGCTTAAGGAACGTTTATAGTTCTGATTGGCAGGTCAGTAGGCAAAGAAATAAAT GGCAGAGCCCGGAGAGAAAAGGATGTGACCTAATCAAGCTGAGCTTGAATTTCAAGCCGAAAGCACAGGCCAGCCAGCTCTCAGCCTCTCTCCCCTA GGCACTCCTGGCTTTTAGAATTCCTACCCCAAACGGGACTCCTCACACTTGGTCAACTACAGATTGCCTCTTCTGCGTAGAATGGGAGGCCCCATCC AATGTATACAGAGCAGGAGCTGTGCTGGTAACAGAAGGCGTTCCAGTGTGCTGACGGAGGCTCGGTGAGGCACAGAGGAGTTCTGTGAGGTACGAGG AGATGGGGCTCTGGCTCGAGGTTCAAAGGCCTGGACCATCCTCCTTTCACCTTGAACCAGTGAAGGACATTGGATGAGTTACATCACTTAAGGGGTG TGTGTGTGTGTGTGTGTGTGTGTGTTGAGAAAAAGAAGTTAATTGTCCCACCAACCTTTGGCTTTGACATTTTATGACTTGGATCTTTCATGAGTAG CCTCTCAGGCAGCTGGCTATGGGACCATTTACAGGAGGCTTCGAGTGGCTTTCCAGGGCCTCTTACATTCTGTCTCTCCTCCAGCAAGACATAGGCC AGCCAGGGACATTTTCAGGCAGAAACTTCTGCTCAGCAAGCCTTTATTATTGATAACCTTCACGCAGAAACCCCCGTTCTAACTAAACCCATCGCTT CAGGGAGGGTGGACATGCCCCCACTAGAAAAGACTAAATGCAGTCTAGCACAGTCATTTGCAACTGCAAGCAACCCAAGCAGGCCTTTGATCCTTGA TCATCTTCCCTGTGAAACAGAGCCTGCCTAACTGTGGCCTCTGGGGCCACAAAGGCAAGGATCAGACCTGCTCAGTGGGGGTGGGGAAGGGAAGAAC ATGGGGACTCACTTGGGAACTGCTTGGTTAGAGGAAATGACTCAGTCCTTGCCCTAACCTCCTGGAAGCCCTGTCTCTGAGACAGCTGGCACTTCTC AGAGAGACCTTCTTGGGGTCTGAGGTGAGAGGCCCCTGACCTGGACCTGCTATCTGGATGTTCTGGGCTGAGTTTGCTTCTGGTAAGTCTTTCTAGA GAGGTAGACTAGGCCAGGCTGCAGAAGCCCCTGTCTCCTTCTTTCTTGCCTTCCTCTCTTTCCCCTTTCCAATTCTCTGGATCTCTCCCTCTCTTCG TACAGTTAACTAATTCCCTTACATCCTCTTTAGGACCCATCAGCCTGCTTCATGCTCCAACCCTAATTTTAGCCAGGAGGGACAGTCCTTCCTCCGT TCTCCACTGTGATCAACTCCCCCTTCCTATGAAATGGGGTGGGGGTGGTGGCTCATGCTCAGGACACCTCAAAAAACAGGTTTCAACATTTCACAGG TTTCAACATTTTTCAGGCGGACTTGTCACACATCTTATCAGATCAGAGCCTTGCAAGAAGCCCTCTTCGGCACAGAGTAGATGCCGGTACATTTCCA GTCACGCTGGGCTCCCTTTGGTGGAAAGGGTTCACCCAGCTTCTTAGATTATCAGGATTGATACCACTTCCCCTCTGATAGGGGTCACCCCCTTGAG TGACCCCCGACTGCATGTTTCTTTCCATATCATCTTCTTCGTCCCATAGATGCCCAGTTCCCGTCTCTTTGGTTCCCCAGCAAGGTGCACTGGCTTC CTATAAAGGTTCCACTGGGCCCTGAAAGGAGCTTCTAGAAGTATCGGGTGAAGATGAGTCTCTGGGGTTACTTCTGAGTGTAGACAGTCTTTTTGGC CAGCAGAGCCAGTAAAGTTCTGTTGTTTGAGCTCCACCGGGACCTCAGGAAGAGAGGAAGAAGGTCACCCTGCCCTGCTCAATGGCTGCTTCCTTCC AGAAGTAATGGCTTTGACATTGGATTTCCCTCTTCACGCCTGAGAGTTTTGCCCCATGATGTGGGTTGCCAGCCTGGTATCACCCTTCCTTCATGTT CTCCAAAAGACTCTGCTTCCCTGCTCCTGCCATGATAATGATAGCCTTGGCGACGTGGCGAAGACAGCCAAAGCCCAGAGGCTCAGAGTTCAGTCTG AGAAGCACACCCGGAGGCTGGTCCCCAGGCCACAGAGAGCGGCTGTAGCCACTCTACTGGGTGGGAGGCCACCTGGGGGGGCAAACTCCACTCTGTT TGTCAGAAAGGAGTCTCCACGGGAGGACCTGGCTGTGATGGCAAGAGCTCTCACCTAGGGAGGAAACAGACAAGGAACAGAGCAGAGGGAGAGACAT TGTGATGGCTGACCGCACGTGCAGGCTGTTTGCCTCTGTAAGTGCTGATGAAACGGGAGCCAGGAACACAGGCTTCAGCCCCTAGCCGTGTGAGGTT GGGCACACCATGCTGTTCCGGCGTCACTCCTCCCTGCCTGGTATATGATATCAACAGTCCCAACCTGAGATTTCCAGCTAGCTCAGCTTTTCCCTGG ACCTTTTGGAATCTTCAGGTCTAGAGTGCCTTTCCACTGTACCTCCTGAGCAGCTATCCTCAAGAGGAAATGCCTGCCTTCTGGGTTCCTCTTTGGG CTCTGCACTTGGCCATGGTCTTCAGCTGTCACTGTCCCCAAGGGTTCCTTTTCCCATTGTTTCTAGCCTCTTACAGATGCCATTCTCTTGGTCACCC TCGTTCAGACCTTCTACATCCCTTCTCTTTGTCCTTATCCACAGCCTTCTCTCTGTTCCCTGAAGCCTTCATCTTGCAATGGCCAGTGGGCCCATCC ACCGCCATAGCCTGTTAGCCTCTCTGGCTCACCTGAGGCCAGGCGACACCAAGGCCTCTGGTGTATCGATGTGTTGCCAGGTCCTCGAATCTCCTTA GTGCCAACTGTCACACCAGCCTTCCATCTGTTTCCTAGCTTTTGATCTCTAGTGCTGCCCTTGTCCCATTGTAGGTGGGAGATAGATCAACAAACCA AAGTCCAGCTCTGGATGCTTCGAGCTCTGCCAGCTTGCCCAGAGTGGTATAAAACCTGGCAGGTGGGGCCCCTGCCAGCCCCCCCTCCTCCTGAATA GTCCAAGACGTCAGGTGAGCGATAAATGGTAACATGGGTACACCAGCTGTTGTCCCCAGCCTCCTAGTTCGAGGCTGCTCTCTGTTCCAGGTGCTTA AGTGAGCCCAGCTTTAATCACCAGGTGTGTAGCTGCTCCTGATCACAGCAGTGGGGACTTACTGGCCCCACCCTGGGAGACTCAGTGTTCTTCCCTA TGCTATGGTAACGATGACTGAGGACATAAGTGACAAAGTAGCCAAAGATCATCTCCTGCTCACGTGTGGCATCCACAGTACCCTGATCTGTAGGTGC TTGAAGAGGGCTCGTTGGCCTGCCGTTGACAGATGTCTCCTGGCCTGGGTGCTCCTCCGTGGGGCTTCATTCATCTCTGTGTTCCTAGCACCTGGAG CTCTGCCAGGTTTGGAGTCATCTCTCAGTAAGCGATGTTGAGTGAGCAGTCGCTGAGTGACTGTGTTTACAAGGAAGGACTTGAGCCCCAGCTGCCG AGACCAAACCCTCCAGTTGCTTATCCTCGCAGGCCCAGACTCAGGCAAACTGGAAACTCAGCCCTGCCCTGGGCTCCACCCTTTTCCCTTCAGCCCC TGTAATGTGAGCTAAAGTTATCTCTGTTCCCGATGGATCCAGAAAGGCAGATAGATATAAGGGATGGAGAGAGGTCCGAGGACTTCCCATGACTGTG AAGGGCAGCATCTAGGTTCCCTTTGTGAACTGACAGCCATGGTGTCACTCGGAAACAGCCCCTTCTTGGTCATACGGTGCTGGGAAAGGTGTAGTTA TGTGCAGAGGGCCCTGTGTGTTCCAGATCAGCATGGATTCTTAGGAAAGGTGGCGGCAGATGCATCATGGGATTTCTCCCTCCTTGCTCTTTATTGA AGCTTCCTGCCATGGTGCCAGGGCTCACACAGGGCCCGTAGAGACTCTAGAAGCTGAGAGAACCCTGGCCCACCAGACTCAGCTCCTTCCCAGTCCT GAGCTTTGTCCTCTCCCTTGTAATAAATCAGCAGCTCTAATTTCCCTAAGTGGAACGGCGATACTTGGGTTCTTTTTGTCCATTTCTTTGATTTTCT TCTGGCTTCTAGAAGTTTCCATATTGCCCAGGAGGTAGATTCTACTGGACCAAAGTGGGTTGGGGCTTCTGTCTAGCATTGCCTAGAAAGTCAGCAG ACAGAATACCTGGTTCTGTGCCCTTATGGGGTTTTGGGAAACCCTCTACCTTCGTCTCCCTCCCAATGCCTGGGCATTTTATTTCATGAGAGCCTAG GCTTTTGGATCAGAATCTTGTGGTTATCTCTGAGATCAGGTGGGTGGCTACTTATCACTGTAAGAAAGAGAAGGGCAAAGAATCCGGTGCTCCCAAG AAGAGTAAGACTCATCCAAACTCATCCCAAGACTAATAGATGAGCCAGAGACCTTCTCCCTGTGCTGTGGCCTGGAAATACACTCTGTCCACTCTGC CAAGTCCCAGAGAAGCTTCTGAAAATGTGTCTTTATCACACCCTGGGATTCACAGGAAGGGACAGAGAAAGAGCTTGTTGGCATCGAGGCAGGGGTC GTGGCCATGGCTGCTGACCTTTCCAGGCAACTGAGCTTCCCCGTGACCCTAGCTCAGACCZGTGCCTTTCTGAAAGTTCTCTGAAATTAAGGGATTC AGAGTTGAAGAGATGGCTCAGCGGTTGGGGACTGACTGCTTTTAAAGAGGACCCAGGTTCAAATCCCAGTACCCACATGGCTCACAGCTGTTTATAA CTCCAAGACCTGACACTCTCACGTAGACATAGATGCAGGCAAAACACCAATGCACATAAAATAAAGGTAAATAAATAAAACTTTTATAGAAAAAAAA ATTGAGGGATTCAGGTAGACTCGGTCCTGGTCATTTCAGCTATTACTAATTGTATAAATCAGTGCATTAGGTAAGTTCCAATGTCAGGCAACTACCA CTATTATTTCTAGAACATTCTCTTCATCCTAAACAGTCATTACTGTGGAGTATGAGCCTACGCCGAGACTGCTGGATCCTGTGGTATATAACAAATT CTCTTTTTAAATGTTGTATATAGAGGAAAAGGAGGGAGTTTGTGCTTGCATCCGTTTCCAAACAAAAATAGTTCACCATTAAGGCAGCCTGAACTTG GTGACACCCCCACCAGCATTCACCATCTCCCTAAGCTCTAAGAGCCTGTTGGGAAGCTCAAAACTTAAAAGCAAACAAAACAAGCTAGGCTGGGATA CAGAGAAGGCTCCCTGGTAGGATGAGCCTGGTGTAAGCAGACAGAGCCAGCCTGATCTCAGCAGGGACTCAGTCATGCAGAGGGATGGCAGAGTCTG TGGGTCTCTAAGGCTCCAGGACACCTCTTTGTAAGTCCCTGCAGCAGCTAAGCTGCCCTGAGTTCTCTGACTAGAGATGCTGGGGCTAGAGATGCTG GTAGACTGCCTTCTCAGCAGGCACAAAGGCCTGAGTTTGTTCCCCAGTACTGATTTAAATACCATAAAATCGTGAGAAATGGACAAAAAGAACCCAA GTATTGCCTTTCCACTTAGGGAAGTTGGTACTAAACTGGATGTGGTGGCCCGTGCCAACAATCCTGGCACTCAGGTAGAGCCAGGAGGCTCAGAAAT TCAAGATCATCCTTGGCTACGTAGGGAGTTCAAAGCCAGCCTGGGATACATGAAATCCTGTTTCTAAAACAAAAACAAAACAAAAAAAGTCTGTATT TCATGAAAAGTCTTATATATGTATATATACTTCTACATTTGAATGAAGTACTAACAAGCCACGTATGCATTCTTTCGGAACTGCTGCAGATCTTTTC TCCATTTTCCTTCTAATTAATTACATCTGTAAGTAAAAAAATATGAATCAACCCATTGGAATGGTTATGTCGAGGTTGGATGAGCACATCTGCAGTC CTGGTACTCAGGTGTCTGAGACAGGAGGATTGCAAAGCCAAGGCCCGCATGAACCACAGACTATGGCCATGTCTCAGAGCAACAATATCTTGGGCTG TAGTAGCTCAGCAGTAGAGCCCTTGCCTTAGCATGGGTAAGGTCCCAGGCTCCCTCTGCAGCCAGGAAAACTGTCTGATCTTGTCACCATGCACACC CACCCACAGCCCTTTGCAGAACAGGTGACAAAGAACTGGGTGTCAGTGGGAAGCTGACAGGGCCATGGGGATGTTTACAGTCTGGCCTAATTGGACA GTGGCATTGGTCGCTATCATCAGCCTAAGCCTTCCTGACATCTATGGCTCATCCACCTGGCTGCTTGCGTCTGCCTGGGCCTGGATGGTAGGTGGTT GGGATGAAGACGAGCTGTCCCTGGGGCTGAAGACAACAGAACCTTGGGTAGAGCAGGGCAAGTCGGGGACAGAAGCTGGGTATAAATAGTCCCTGCC CAGCTGGGCAGGCCTGGCAAGCCCTCCGTCCTCCCCCTCACCAGCTGCCAGTGCCAGCCATGCCCCGACCTCCTTTGGGAGCCTGGTCACCATCTCA GATCCTCACTGGAGGAAGTCCCTCAGCGGAACTGAGGAGTCTTGTCCTGTGTGTGGGCGAGACCTCCGGCTGCCCGAGTGGGGGCATCAGGCAGGCT CTTCGGGGTGTCCTCTATTTTCTTAACTGGAAGGCCAAGTGTGCTGGTGTATGTGTGTGAAAAATCAATAGCTATTCCTCTTTGTGTGTGTGTGTGT CATGCTGCAAACAAATGAGCCAGCCTTCTGTGGTGAGAAGGGGAGAAGAGGGTACGGGGACACTAGCAAAGGTTACTTCTAGCTTGGGAGCTCACAG AAGTCTTTAGAAGTGATTCAGGGAAAGTTTGACTTGGGTATGGGCTGCAGAGAGGCACTCAAGGAGAGGGCTCAGCATGCGTGAAGGGTGTGAAGCT GTTTCAGCTGGCCTCAAGGCAAATCTAATCAAAGCCTCTCACAGTGGGGAGATGGAGAAGATCAGGAGCCTCTCCTGTTGACTCTCCCAGGGGCACA AGCTCTTCTGTAACGGGGACAAGAAGTGGGTTACACTGATATGTCTGCAGCAATGGAATGTCAGCCATGGTGTGTGGGCACGGCTCAGGGCCGGCAG GGCATGTCAGGGGGGACAGCTGTCCTGCAGAAGTCAATCCCAAGGCCATAGCCTCAAGGCTGTCCATAGATCTGAGCCCTGTCCCCAGAGGCCCTAG CTAATTACCACAGGATATCCAGATAGAGCTTGTTGAGACCTCTGACCGGAGCATCCTGGAAACCCTCCCATGCCCCTTGGTCAGTTTGAACATGCAT CCAAGTCACACATGGCTTTGCTACGCTCAGCCTGTCAGTCACAGAGGGATTTGCTTGGCCAGCCCTGTCAGGACTGCTGGTGAAGAGACTCTGCCGT GTCTTGGAGCCTTCCTCCTCGTGCTTGATGGGAAGTGGCTTTAGAAATTCTGATGTGCTGTATCAAGTCAGGGAACTGAGGCTCCGGGAAATGAGGT TGGCGACCCGGCAGGGACCAAGTCCTGAGAGCATGGAACCTGAGGTGGCTGCCATTGCTTGAGGGATCCTGATGTGCATGGCACTGAGCTGTACATG TTTACTCTTCCCGCAAGCTCTGTCTCACAGTGGAAGAAAGTGTGGTGTGGAGAAGTTAAGGAAATCGCTTGGATTGGCAGCTTGAGGCAGGCAGAGC CCGATGTGAGCTGGGGTGAAGAGACAGGCTTGGAAGGAGGAGGGAACCTAACTCTGGGTGACAAGTGTCTACACTGAAGCCCTTGCTGGGGTTTCCT TTCTAGTGTCAGTAGGGCTTAGGGATGAGTGGCAGGCCAGGGCTAAGTGCTGGCTTAGTGTGTGAGAATGAGCTTGATCAACAACACTGCAGAGAAA GGGCCTGGTTGGGGGCAGGGGTCTGTAGGGAAGGAAGAGAAAAGACAAAGACATGCCAAGAGGGAGGCTCAACTCTGGCACTTTTACGACCCACAGG TCCAGGCAGCTTACTTAGCTCCCTTGCCTCTGTTTCCCCGTCTGTGAAATGGGATGATATTGATGATGACACTCTCTTTACCTCATAGACTGGTTGC GAGGATTAAATCAGTTAAAGACGTAAACATTTCAAACTGTGCCCAGCTCAGGTCAGATATACATCCATGTTAGGTGTTTTTGCGGGGCTCCCCTATG CCTTTATGTGCTGTGTGGCTTCAGGCGCTAGGCTCACCATTGTTTCTCACTCAAACGTCAGCCCACCAGCGGGTAGGCAGGCCAGGCCTGAAGCCAC CCAGCTCCCTAGGGACCCAGACAAGCATTGCCCACGAAGCAGAGGGAAGGCTTGCCTGGGAGCCAGGTAGTCTAGTTTCTAACAGCAGATAGAAACT CTATAATCTGGGCAGCTAGTAAAGCCCCCACTGTGTGCTGGGTTGTTATCAAGAACTCAAGGAAAGTTAGTGAAGAGTTGGTAGTGAGCCGTGATGG TGTGACACTAATGCTTCAGTGGTCACCTCATTCTTTTTCTCTCACTCTTGGCCAGTCCCAACAGGAGACAGTCTCTTGTAGCCCAGGCTAGCTTGCA CCTCCTGACCCTCTTGCTTCTGGCTCCCAAGTGTTCAGGGATTACTACCCACCTTCCTAGCTTTCCCTTGTCAAAAGGGCCCAGGGCTCTGGTTGGG GAGAGCTCAGTGGGAGATCAGTTGTCTGGCAAGCTTGAGGCTTTGAGAGGTGGGGTTGGGGACTCTAAGCTCAGGACAAGGTTCTTCAAGGCCACCA ATTCAAACCCCCCAGTTCTGCCTACTGCACTCTCTCTTCCCAGTGGGGAAACCTGGACTTCATCCCCTGACAGCTGAGGCCAGAGGCTGCTGGAAGT GGTGCTGCTGTGTGCCATGTTTTGCTGGAGCCTCTGAGCAGAGCAACCGAGGCTCTGGGTGTTGAGTGTGGGGGAAGGGTGTTGGGAGGCAGCTCAC AGCATACTCTGATTAGACTCTGATGAGCCATATACCTGTTCCCAAGAAGCCCTAGGGCAAGCTAGTTGTTCTGGAAACCCAGATTCCTCATCAGGGG ACAGAGATGATCAAAAGCTGATCAAGTCTGTTACATCCAAAGTTCTAAGCAATACAGAGTCCCTCAATGGCCGCGTTCGGTTCACCCCATGCCAACG AAGCTTTTGTGTCTCTTCTGACCTACCCCAGAGTTTGCCCCTGGCCCCTCTTCCAAGGCTCCTGCATCCAGGACTTGACCTTAGCTAGTGCCTAGGT CTCCTTTCTTCCAGGACACTCTGCCCTTTATTATGAGCCTGGAAGAGGGAAGGAAAAGGTAGAGTTCTGGTAGTGCCTTGCTTTTTCTACAGTAGTT AACCCTTTCCCCCCCGAGTGTACTTACCGGCGCTGTAAAATCCCAAGGGTTGAAATGTAAGAGGTACAATAATGGGGTGGCTTGACTGAAGTGAGAA GGTTGGGGGGATGCCTGCTGAGAGTTTCCTTTTGCTCTTGAGTTAAACTAGTCATCAAACGGAGCCTCTGTCGCTAGTGAGAGGGGAGGTGGCACTC TAGAAACTTCTAGGGAACTATAAAGATGGTGGCGGAGGCCCTTGTAGACAGAGCACTTGATGCCATCAGAGACAAACAGGCTCTTGGTGTCCTCTGT ACTCTTGGGGAAGAGGCTAAGAGGGCTTTGTGGGGAGAGAGAGAGAGAGGGGGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA ACACTGTGCTAAGACTTATGCTCCCCCCCCCCCAAGATGGAGCTGTGATCACAATGGCCTCTGCTTCCTTTGTCCTTTATATTTGGATTCCTTCCCA TGAATGGCTGTTAGTCTCCACATGACCCACGAATCCTGGAGTCCCTGGGAGATTGCTCTGCAGGAGCCCTGCCATCTCTACCAGGGCACCGGGGCCC AGGCACTGGGCAGAACTTGATTCCTGCTCCAATTCTTCATTTCCAACCCAGGGTTATTTTTGTGGCACAGTACAGACCTACACAGTGCCCCCTCCCC CAGAGGCTCTGCTGCTCCACATGCCCATGTCAGAGGGACACTGCTTGAACCGGTGCCGTGCCCTTTGTGGGACACCGTGTCCCCAAGGAAAGTCAGA AAGCAGCACACAAGGTGCCAGGCTTCTCAGAGCCACGGATCATCCCTCCCCCACCCCAGCCCATCCTCTGGGAAGAAGTGACATCCATACTAGGCCA CGTGTTCTGTGTCTACAGTGCCATCTCCATTGTCTGCCTGCAGGTCCCTGGCCCTGGGCCAGCAGTACACATCTCTGGCCTCCCAGCCTCTGCTCTG CGGCTCCATCCCAGGCCTGGTCCCCAAGCAACTGCGCTTTCTGCCGCAATTACATCGAGATCATGCCCAGCGTAGCAGAAGGTGTGTGCTGGGCATC CAGGAGTGCCAGCATCAGTTCCGGGGCCGCCGGTGGAACTGTACCACCATAGATGACAGCCTGGCCATCTTTGGGCCTGTCTTGGACAAAGGTACTT GCCTGAGACTCGGTGGGAGGTGGCTGGGAGACTGGGGGTGGTGGGAAGGGTTCTGGGGACCCTGTCCCCTTCCTCCCACTGTGGGAAACCCTGAGTC CAAGTTCTCCCTAGGAGGGTAATAAAGCTGGTGGAAAGTGGGTGGGGTCCATCTCTGGACAGGACAGGCTGTGTCCACATCGGCTACATCTTTTCTA GTGCTACAGGGGGGTGGGTAGCCCTGAGGTGCCCCAGTGTCCTGAGATTGGAGGGCAGGCACCAAGGAGCCCGGAGCCTTCCTTCCCGGATGACACA CCAGGCCTAGGTGTTGTGCCATGGAAAAAGTCTCTATGCTCTGTCAAAGCTGTCTGGTGCTGGTAGCACTACATGACCCCCGAGGGTCCCCTGAGAG TTCCTGTTGGTTCCCATAGCCTGAAAGCAAGACGCGTCCATTAACCCTGATGTCCTGTGGATCACGCTCGGTGATCTGGAAGTCTGACCAGCTGTGA CCCTAGTGGATGAAAGCCGGCTTTTGACTTTGCACATGGGGCATAGGAGAGGGTTGAATGGGGTAACTGCTCCTAAGAAGGGGACTTTGGCTCTAGA ACCTCTCCTGTCCAGGAATTTAACGGCCTTAGCTGGGCTGGCCTCGACTGGAGTTTTGCCAGCCGATGGGGGCGAGCCTGCTCTGAGAAGGTTCGTA AAAGCTGCATCAGAGCAAAAGGGAGGAGTCCGAGAGCTAGCGGGAGGGTGGGCGCAGAGTTTGGGAGAGGGGAGCTATCCCCCCCCTCCTTTGGAGA AAGCCCTCTCCCCCTTTACCTGTGCTTCAAGTGCAAAGTGTCTGTACAACCTACAGGCAGAAAACGCAGGCTATTGTCGTGGGACAGGAGGGCAATT AGCAAATCAATGGATGATGATTCTGTTTACGCTTCTAATACCAAAGCTAATTATTCCTTGTTTACATAAAAGGTTTGGCCTCTAATTGGGGCCAAGT GGCGGCGGCGGCTGGCTTTTCAAAACTGATCTCGCCCGCCTGTTGGTCTCACCGCCTTCCGGCGCCCCACCTCAGTCCAGGTAGCGTTTAATCAAAC TGCCAGGCGTCCCGACGCCTCCCCCAAAGCAACACTGGCCTTCTGATCACTCCTCCCACCCAGGATAGTGTCCATCGAGACCCTTTCAGTTGATACC CGCTCGCAGTGGGTCTGATGTTTAGATTCGCAGCAGTGGGTTGTGCCACATGCCTCCGTCCCACAGCAAGAGGGCAGTTTGTGTCCCAGTGTGCAAG GAAATATGGGGCTGAGACAGTGGGATTTGATGAAGGCAGTGGGGTGAGGTTCCAGGAAGATGTACCCGCGTCCCGGTACCCTGTGGGCAGGCGGTGG GTCCTGGCCACTTTTGCGCACGTCCTAGCAGGTGCGGGGTGGGCGGCCGGAAGGCGCAAGGCCGCGGTCCTCCGCGGCTCCGGAGGGTTCGAGCGCC GCCCCCCGCCGCGCGCCCGCTGCGGTCGCCGCGCAATTCACACGCCCTCTGGCCGCCGCCTCCCGGGGATCGCGCTGCCCGGCGCCGGGGCTGGGGG CGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCAGGCTAATCCCCGCCCCGCCCCCGCCACCCCACTGCCCCGGCGTGGGAACTGAGCG TGGCGGGGCCGGGTCGCCGGAAGCCAGGGGCGCCCTCCCCTGGGGCGAGAGGGCCGGGAGGCCTGGATCACCGCCGTGCGCAGTCCCCCCCGGCTTG GCTGGACTGCTGAGCCAGCTCTCGCTCCGCGCTCCCCGCGGGCTGCGGGGAAAAGTGGGACGCGCCCCTGCTGTGCAGGTGGCGCACGAGGGCTTCG TGTCTGCAAAGGCTGCTGTGGCTACTGAGTATCTGGTTCCCTGCATATTCAGCACGGGCCACGACCTAGGAAAGGAGATCCGGCTCTGACCACCTGT GCAGTATAGCACGACCCGCTCTGGGAACCTATAAAAAGAGATGGCCCGGGCCGTTGGCCTCGCCCGGCCCTGTCTGTAAAATAGGGGTTTAGTCATT GTAGGGAATAAAGCACAGGAAAGACAGATCTGCGCGTATGCAGTACTCAGGGAGTGGCTCTCATTGTAACAAGGCTGGTGATGCCCGCTGAGACTCT CATCTCTGAACCCTGGGCCTGAGGCCGAGAAACTGCCTTGTCTCGACCCTCGTGGCTTCGTAGGAGGAGGGCAAGAAATGGGCAGCCATGGCTGAAG ATGCTGCACCTACTTTACAGAGTGTACTGTGAGGCACAGATGAGAAATCTGCCTACGGGGAACTGAGGTTCGAGTGGAACGAGTGGATTAGTAGGTT TTAGGCTGCAGGTTCCAGTCTCCAGAATGGAGGACTCAGAACTGTTAGGAGGAGTGTTTCTGAATGTGCAAGGTTGGAGGCCAAGAGCCCAAGGACA GGGCGTGGCCAACCTAACTCTTCAGAGAGCATTCCGGTCCCACCATAGACCCCTCCATCTTAGTAGCCCTGCAGCTCTGAACTCAGCTTGCCCATCC ACAAAGAGAATACTAACTAGGGTCTGAACTCTTTAGAGCAACAGGAGGGCACCTGGCTCTCTTCCCCCAATGACTGGTGAGCCTTTGCGCTCTTCCC CAGCCCTCAGGGCAAGGCTGTGTATGTACCCTAAGGCTCGAGGCTGAACATCTTCTCACACCXTCCCTCTGCAGCCACCCGTGAATCGGCCTTCGTG CATGCCATCGCCTCGGCTGGTGTCGCCTTCGCAGTCACACGCTCCTGCGCTGAGGGAACCTCCACCATCTGCGGCTGTGACTCACATCATAAGGGGC CACCTGGAGAAGGCTGGAAGTGGGGCGGCTGCAGCGAGGACGCCGACTTCGGGGTGCTGGTGTCCCGGGAATTTGCGGATGCGCGGGAGAACAGGCC AGATGCCCGCTCAGCTATGAACAAGCACAACAATGAAGCAGGCCGAACGGTGAGACAGCGACCCACAACTCGGGGGCGGGAGGCACTCCCTGGACCC CTGCCTTCACGGCCAGGTTCCCATCCACACCCCATAGTAACCCCCTGACCACCCTCCTTCCTCTCTTCCAGCTGTCCTTTGAATAGGTTTTTTAAAG TATATTTACTCATTCTCAGTGTGTGTATTCCATGTTGTGTATGTGGAAGTCAGAAGGCAACCTGTAGTGGTCAGTTCTTCCCACCATGTAGGTTTCC AAACTTGAATCATGCTTGATGCTGTTCCTGGATCTTTTGAGAAATCTGCCAAGGAGTGCAGTATGGCTGCCCCATAGGAACAACACCCATAGGCTAC ACTGGTTGGCAGGCTGTGCCTGTGTACGTCTGTGATGTGGTTGTGGGTTGGGGACTGACTCTGAATCCAAAGTAGGGTTTCCATAGCATAGCCCTTC CTATGCTCGTGGAACACTTAGCTCTCGGCCTCAGTTTTTCCATCTGTTCAATGGGAATAACAGTCCCTAGTTTGCACCACTTCTATGGATGAGGTGA ATGTGAAGCCTGCTGGGGCCGGGGGTGTGACTAGGGACACTGGTTTCCACCCATTCTTCCTGGCACCAAGTAAGAGTAGAGGAGGGTGTGGTACAGA GGGGAAGCTTTCTCCCGGTGTGTCAGTCTGAACTAGCTGCTGCCCCTCTTTCCCTAGACCATCCTGGACCACATGCACCTAAAGTGTAAATGCCACG GGTTGTCCGGCAGCTGCGAGGTGAAGACCTGCTGGTGGGCCCAGCCCGACTTCCGTGCCATTGGCGACTTCCTCAAGGACAAGTACGACAGTGCCTC CGAGATGGTGGTGGAGAAACACCGTGAGTCCCGAGGCTGGGTGGAGACCCTGCGGGCTAAGTACGCGCTCTTCAAGCCACCCACCGAGAGGGACCTG GTCTACTACGAGAACTCCCCCAACTTTTGTGAGCCCAACCCAGAGACGGGCTCCTTTGGTACCAGGGACCGGACTTGCAATGTCACCTCCCACGGCA TCGATGGCTGCGATCTGCTGTGCTGTGGCCGGGGCCACAACACGAGGACGGAGAAACGGAAGGAGAAATGCCATTGCGTCTTCCACTGGTGCTGCTA TGTCAGCTGCCAAGAGTGTATTCGCATCTACGATGTGCACACCTGCAAGTAGTGAGCCAGGTAGGGCGCGGGGCGGGACGTGGGACTGCCCTCTCCT CCCATCCGCTAGGCCTGCTCTTCTGATTCTCGGCTTCCCAAGACGAACAAGTTCCCAAAGCTGAAGTCAGAAACTAGGCTTCCCACGCTTCCACGGG AATGGTCTTGGGGAGCGACTTGACGTATTTACACGAGGCTCAGATAATGACTGAGGGTGTGCACGTCAGCCACAAGCAATTGATTAAAATTCTTACA CAAATTAGCAGTGATGACCCAGACCAGATTTGTTCATGGCTGCTGGCTGTCATTAGTGAGCATCTATTCGGCCAGAAGAGAGGTTGAGGTCTGGTCC CAGCCATGCCCCTAAAAGTGTCATATCTCAGGGCCTCAGTTTCCCTACTGTCTAAAGGAGAGGTTCAAATGTCAGAAACAGGGGCAGGGTATGGTGG GACTGGCCTTTAATCCCAGCACTTAGGAGGCTGAGGCATCTGGATCTGAGTGTGAGGTCTGGCTGGTCTCCATAGAGAGTTCTAGGCCAGGACTACA CAGTGAGACCCTGAGACAGTCACCTAGTAAGTCTCTCCTAACCCTGGGGCAGAGTCATTTCACATCACCCATGAACTGAGAGGGCAAGCTTTGACCT AACACAAATCCTCCAGAGCTTGGGAAGGTGGGTGGGGGAAGCCAGATCTGAAGCTTGGGTGGAGCGGGAGCACTCTCACCAAGTTTATGGAGGGAGA CAGGAAAGAGGAGAGCTCCCAGTTCAGGCGGCTGGGGTGAGTGACCGTGGGATAAAAGCCTGGTGGATTATGCTTACCAAGCTTCCCAGAGGTGGCC TGCATGCGTGGGAGGACCCCAAGAAAGGTCAGCCTGGAAGCAGAGTGATCCTAGAGGCTCTGGCATGGGCCAGTGTGACCCTTGTGTCTGTCCCCTC CCCTGAGAGGGCTCTGCTAGTGAGTCTGACTCTCAACTGGCTTTTCTTATTTGTCAACCAACAACTCTGGCTTCAGCATCTGTTACCTTCCCCGAGC AGCTGTGAGGAACGTGGGAAACCACATTGGTTCCTGGAAAAGCAGCTTTCTGTCCATCTATGGATGGCCAGCGCAGGTGTGTTCTCCCAGGGACCTT GGAGCTGGTGACACACCAGAGCTGGTGGCTCATGTCTGCGCTCTGTAAGGGTGGGGGGGTACCTGACATCACAAGCCCATCTAAGAAGTTCCTTGTG GGGCTTAGGTTCCATTCCCAGGGTCCCTCTAGAACCATACAGGAGGCGTGGGTTTTCTTTATCAAGGTCAAGGCTGGAAGGAAGACAGCGGCGAGCT TTAGCGCTTCACGCGCCCACTGCTGAACCTCGCTCCTCATCTGCGCAGTGATGGCAGTATGGGGATCTTGATGGATTTTTATAAAGCTCAAGTTAGT GGGTGTGAATGCTGCTCTAAGTGTCAGGGTTGCCATCAGCGTTAGCACGGGGTTGCTGCATGGTGATCCCATTGCGTTCTTCTTTCTGCTTTTCAAA GGGATGGGAGAAAAGTCAGCAAGTAGGAAGGTTGAGGTGGAAGGAAGCAGACCATGACGGCCGCCTTCTCTGGTATTCACTCTGACAAGAGTTAGCC CTGCACCCCCCAATATCAGATAGTACATACATAGCTCTGGCCGTTTTGAGGAGCTCTTGGTGTGGCTTCTTATCACTCAGCTAGAAGGGCCATTTGT CCTGACCGACCCCATGTCACTGAAGGTTAGACTTGAGTTAATGGCCTAGATAGACCCAGTGTCTGCTTCCAGTGCTTCGTATGTAGGCTTGCATAGG CCTCAGCATTGCCAACCCAAGCTTGATACATGGGGCAGTGTGGGTCCAAGATACAGAGCCCATGACTCCACTCCGTCCTTGCCCATGTGGGCAGCTG AGATCTTCCAGGCAGGGAAGGAGGTGCAGGGTGAGCCTTTGTTGTCCAGCAAATCGCTCCACTCCAATCCTTGCCTAAAAATGATCTCCTAAGAAGA ATTGGGTGTAGCTGGGTAGTAGAACACTTACACCCCTGAATCAATCTCCAGTACTGGGGAGAGGGGAAAGCAGCCCCCTTTCCTCACATTCCTAAGG TAGACACTTGCTGTTTTTCTAGTATCATGCAGACATGTTTTTAAGAAGCTATGCCCACAGAGTTCACAGCCTTAATCCCTTCCCATGGGGTGGGGGG TGGAGGGGGGAGGAGGACTGGACTCTCAACCTCACACTTCCTGATAAGAAAGATCCCTCCCACTGGGATGTCCTTTGCCTCTCGGAGCCCAGGTTTC CTCCTGTGTGAAGTGATAAGGTCTGTGCCCTGCAGGGCTGCTCAGGAGCCAGACACAGCCATAAAGAGCCTGCTCTGGGCTCCTGGTTTGGAGCCAT AGGCCAGGAGATGGTTGAGACCTGGTTCCTTCCTGTCCTTTCACCCCCGAAGGCGCTGCTACTGATGGAAGCCAAGGGACAAATGGGCAGGGAGACA GCAGGCATAGAAGGCTCTGGCTTTTTTCTTGCACAAAGGGGCCACAGAGCAGAGCCCAGCAGGCCACATGCCCTTCTCTGAGAAGAGTTCAGCACAG TGGTAGCATCCAGTCCTCCCTAAGTGGGGAAGACACCTTCTCCATTGCTTGAGGTTTGTCCACTGTCTCCACTTAGCCACTAGCTTGGTATCCGAGT GCTGGTAGTTTACAAATATCTGATTTATTCTTTTTATCCCTATGTCGAAAGGCTATGAATCTAGTCACCCCCTCTAACTGGCCCTGTGTCCTGGGGT CTGTTACTAGTCTTTGTGGGACCTTAGGACATATCCAGGTCGTCTTGCTATGCCTGGTTCAGCTCTGCCAGCAGCACCAGAGATGAGGGTTGGCTGG GGGTTGGGGGGTGCCTGGGGCGTGGCTCAGTACCTCAGATCCCACGGGATAGGGCTGTACAGAGTGATCATGCTCAGGAAAGCACCCTGGGAGGGAG TTCACCATAACTAGGTAGAGTCGTTTCTTTTGGACAATTCCACGGCAGTTGTGCGTCTGATGGCAGGCACTAGCCCTGCTGTGACTGGTGGCTCAGA CTGGCAGGCTTTTCCGTCTCCACGTAGGAAGGGCAATGCTCCCTTGGTTACCTACAGTGGGCTTCCTCAGCTAGGAGGAGGTTTGAGTTTTGTGGAT GCAGGCTCTGTTCTTCCTGAGGATGGCATGTCCTCCCTCAACAGCAGGCTCTGGGGCGAGGAGGGAGGCAGGGCTGGCAGCGTAGGCAGCCTGTGAT CTTTGCATCCCAGGGGGTGATGTTGACAGCAGTTATGAGGTTTCTGATTCTTCCTGTTTATTTCCCAAAGGGCACTGGGAAGGGGTAGATTGTGCGG CTGGATCCATTCATCGAAGTCCCATGAGAAGCAGGATCTAGATCCAGGCCAGCCTTCGGCACTGGCCAGCAAGGAGCATGGACTGTTGCCAGCTGCA TGTGATAAACGACCTGGACCCAGCCGGCCTCGGACGGACGGGCGGCTTCTTTCTCAACTAACGTCTCTCCCCCTGCTCTGGATGGTGTACGGCTTTA CAGAGGGGCTTTCTTTATGGTTTTACCAGGGTCTGCTGGGGACAGACTCGAGGCTTACCTTTGCACATGTTAAAGAAAATAAAAATGAAAAAAAAAA ATCTACCGCAACAGAACAGGCTGGGCTAGTGTGAGCTCTTGGCCTGGTGGGAAGGACAAGACCATGGCGAGATTCTGTGTCCAAGCTGCCCTCTATC GTGACATTCGAAGATGCCTCTGAGGTGGGAACTGTGAAGTAGGACAGAGCCCCGCAGTCCCCTCTTGTCCGTCGACTCCCATTTAAATTGGACATAC CTTGTCGTTCTGAGAAAAGCCATAGATAGGTGTAGCTGGGATGTAGTGATGGGGAGGCCCCTGGCCAACAGTGGGAGCAAGATCTTGAGTTTTGAAG ACCTCAGAGTTCTGGGCGGCCTGGGAAGCCATCTGCAGAACAGAGTTCCTTGTGGGCTCAGTTTTCGCTAGCCCCTGTTCTGCCCTGGAGCGACAGT CAGATCTCCACGCCCGTTTCTGTTGTTCTACAGTGTCCACCTTTAGTACGCGTTTTTTTTTTTTTTTTCATGATGACCTTGTAAATAGGTCAGATGT GGAGGCAGGTCTCTTCTGGCTCCATCCACCACACCCAGAAAGAATGGGCTGCTCTGCCCTTCTCAGCCTTGCTAACCAGCAGACACCGAGGAGAGCA GCGGGGCACGTTAGAGAGCAATCTAACATGGTTGGCAGGTGGGGAGGGTAAAGAGTCCCACTTCCTTTGTGTGTTAGAAGGTGACTACCCTGCGTCC TTTTCTCCCATTGGCTGAAGTAACCAGAAAGACAAGAGATCCTTAACAAGCCCGTTCTTCCCACTTGTAAAAGGATAGCCTATCTCAGTTCCCAAGG ATCTGGATTAGATAGATATTCAAAAGAGGCAAGCAGCGAATGGAGGCAGCTCCCAGCTCTGTTCCCGACGCATGATGGTACTGGCTGGGTTTAGTAA GGTGGGTGGGGCTGCACGGATCAATCCATCAACTCCGTCTTAAGGAGAATCAGAAAGAGGAGATAAAATGGGGGAATGGGGCAGAACAAAGAATTTG TCCTTTCCCGCTTCTGTCTAGGGTCTGCTAATGCTGGCTTGACGAGGGGTCAGCCACTTCTTTCCTGTTGTGCAGTTGGCTTGCCAAGCAGGCTCCA GTAGGCCCTTGCCTGCACTCTCTACCATGTGACCATGAGCACTGCTCTAGGGACACCTCCCATCCCTTCCTAGCACCCCAAATGCCCCTTCCCATCT CTCCTTCCAGAAGTTGGAAATCAAGTCAACTGGATAACGCTTGTGTGAGGACACTTGAGCAGAACGGATACAACAATTTACAAGTCTCTTCATATCT ATGTATTCTATATTAAAAGTGATAAAGTCATGTTTCCGGGGCGTATTCAAGTAGCTGACAAGTAATTATTTAATAATAGTACATGAGCGCATTGTAA TTATCCTCGCCATAGTCAGGTAATAGCATCCAATGGGAGGTCCCTACCAACCTGCTGTATCCAAAGTTTTGTAAAAAGTTGTAGAAGTTGTTGATCT TTTTGATTTTATATTCAAAAAGTCTCTTTTTATAAATATTATTTATTATACAATGTATATACCTTTGAGTTAACTAAGATTATATATTATATAAATA TATATATATTTGGAGAAAATCTATTTCATCATGCAGTTTTTTTCTGTTAAATCATTAAAGAGAAGGTAAACTTCAAATGGACACATTGTACGATGTG TGGAGTCTCCAGATTCGTCCTTAGGTCAAGGGTATCTGAATGTTGTGCTAATTAAATGGCCAAATTTACGGTCATTTCCTCTGCTCTCTAAGCAAGA TGAGGTATGATGGACAGCAGATGTGACATGAGCCTTAAAGCATTACTTGATATTAAGTCAGTATCAAACAAGGAATTGCCAACTTGGGGAAGAACAA ACCTGGTCAGCAATTCATTCATAGACTTGAAAAATTTCAACAACGCATGTTGATGTCTCAGATCTTTCTACAAGGTTCAGCCCAGGTCAGTGGGTCA CAGGGCCTGCCATAGTCTTACTCCCTTTCTCACTACATACCCAACTCCAGTTGTTGGAGAAATAGGAATTGCTCAACTGTAAACAAAGCTGGACCAG AAACAGATAACAGCTGAACTGTGGAAGAGGTTGGTAGGTAGGTTGACCAGATGGTGTTCTGCCTGTGCTCTGGGCCAAGTGACAATGGAATTGTAGG TTGGTTTAGATAGGTTGCTGGGCAGAGCTCTGGGAAGGGCACTCTCTCCTTGGGCTGGAGTTTCAGTGACTCACCCGAAGCCTTTGCCTGTCATCTT GATGCTGTGCAGTTTTAGGATGATGGGTGGTCCTTCACCTCTCAGACCTCCCTCTAAAATATCCCCTTCAGTGTTCCTTTCTTCTGGTCTACCACTA TTAGAGATAACGTATTCACACTGGCCATAGGAACATGAAGCAGTCTGCTTCTGACGGTGGGGACTGCCAACACCTTCTGGCCCTCGGTTGACCATGA CCGCCTGAGCTTCCATTTGGTGCATCTTTTGCCCCTAGAAATCTTTTTCCACCTATGTGAGGCCCCTTGAGGGTAAAAGCAGAGCTCCTGGCTTCAG TGCTGGCCATCTTTGACTGCATTTCCCTTGAGCTGAATACTCTTTTTTTTTTCTCGCAGCACTCTGGGTTTTATTTTATTTTATTTATTTTTTTGAC TGTATAAGGTTGCCAAGTATTTAGATGGTCCCTATCATACTTACCAAGGCCATTTGTCTCCCATGATCATTGTATTCCATTAAAGAGAGTACAATTT ATAGCTATGCTAGAACACTAGCTGGAAACACTGGAAAGAACAAGTTTCAAGTTGTGCCTAAGTCGTGTGTGCACCTTTTAATTTCAGCATCTGGGAG GCAGAGACAGGTAGATCCCTCTGTTCTTGGCAGCCAGTGCTACACACCAGACTTAGTGGGTCTTAAAAAAAAAGTTTTGAGAATAATTTGAGAGAAG ATAAAGGGATATGGTGAGGTTTTTTTTTTTTTATTGAAAGCAACACTATTCTGAAGGCAGGCTGTGGGTAATGGATGGGCACAGAGATAGGAAAAGG AATCGAGGAGAAAGACAGCAAGGGAAACGAGGCGAGGCTGTTTTGGGTGGAGTGCTGGTCGACCTGTGTAGTGCTGGGCATAACAGCACGTAACATG GGTGGTGTGGGTCTACATTAGGAAGTGAGTTCAGCAAAACGTATGGTGTTAAGCCATGACTGGCTTAACAGAACTTGGGAGGCAAACAGCTATCTCA TCACTAATCAATCACCAAATGTTCATTATGGAGACTGTGCTGGAGAATCATAAATACATGTCATTACAATTTCTTGTTTGGACATAGTCTCACTTTG TAGTGCTGGCTATCCTGGAACCATGCAGAATAGGCTGGCCTCAATCTCGTGCTGATCCCCCTTCCTCGCTACCTCTGGGATTAGAGGTGTGCACCCT TCCCTCCCGATCTTGGGATTCCTGCGATCACAGGTGTTATCCGTGCTCTGGCATCACGACACACTCACACCCCCTGGGCTGTCATGGGGGCTCAGCC TCAGCAGTTGTCAGCAAACGAGTGGCTTTCATCTTGCAATAACTTCTAAAATTTAAATGCTGCTTTTGAACTCTTAGCAAACCTTGCCTGGCTTCAC TTATTTGAAGGCGGCAGGCGCCCAGCTGCCAGGCAAGCAAACTGAAGTCCTGGCCTTGCCTTCTGTTTGGCCAGGTGGATATTTATAGCTGACCCCT GCTTCAGCAGGCCTGTTGACCGAGGCTTGATTATTAAATGATAACTGAATCTCCTCCATGATTCTGTAACATAAGGTGGGAAATGTAAAGGCTGCTC ACTGTAATTTTTAGGCAATAAAAAGACAGCCTTAAAAACACATCTGAGGCTCGATAGATGCCCCAGTGTTGGGGAATCGAGGGCGGGGAGGTGGGAG TGGGTGGGTGGTGGAGGAACACCCTCATAGAAGCAGGGAGAGGGAGGATGGGATAGGGGGTTTCTGGGAGGGGGAGGAAAGTGGAAAAGGGCTAACA TTTGAAATGTAAATAAAGAAAATATCCAAGAAAAAAGAAAAAAGTATTCAAAATATATATAAAAAAAAAAAAAACCACATCTTAGATTCTAGCTACA GTTATGCATGTTTTTGGATAGTACATGAAAAAAAAATCCTCAAAAGAAGACAAAAATGTAGTAAGGAAAAAATGAGCTCTTCTTTGGAAGATTTAGT ATTTCCTGACAGCCGGTGTGTGTGTGTGTGTGTGTGTGTGGGGGGGGGTCATCAGAGCCCTCCACACTGTTCACAGGGCTATGCTGTGGGCTGGAGG TGGAAGGCCTTTGGGGATCCTCCCAGAACTGGAGGTGGGGGGCAACTGCTGTCCCCCAAATTGCTGGACATGCCTCTTCTCTACACAGCATCCATTT CTGGGCTTCCTGGTGCAAGGACTGGGGCTGTGGCATCTAGTATCTGAGAGATCCAGAAGGTATGAAGAACAGCAGGGTGAGCTCGGGGGTCTCAGGT TTGCCTGCTTCAGAGAAGTCATTGTACCGCAAAGCAGCTTCCACCCAGCTCCTGAACAACCGAGCTCATGGCTGCAGTTCAGACTTTTTAAGGTAAA ATAGGTATCAAACGTAAATATGAAGATTCTCGTACATTAGCATATACTAATGAACTTTTGAGGGGTTTGTTTTGCTTTTGTTTTTGGAGACAGGGTT TCTGTGCAGCTCTGGTTGCCTGGAATTCACCCTGTAGACCAGGTTGGTCTTGAACTCACAGAGACTCACTTGCCTCTACCTCTAGAGTGCCTGGATT AAAGGCATGCGCCACCACTGCCCACTGAACTTTTTGTTGTTGTTGTTGTTGTTTGAGAAGAGTCTCTCTGAATGAATGGTTCCCAACCTTGCTAACG CTGTTTGCCTTTAATGCCGCTCCTATCATGATGACCCTCAACCACAACCTTGCTTTTGTTGGTATTTCATAACTGTAATGTTGCTCCTGTTGTGAAT TGTAAGGTAAATACCTGTGCTTTCTGATGGTCTTAGGTATAACCCGTAAGTTGAGAACTACTGTCCTACAGGGTCTTGGGACTCACTATGTAGAGTA GGCTGGCTTCCAACTCAGAGATCTGTCTCCCAAGTGCTGGGATTAAAGGCATGTGCCGTCAGCTTGCATGCGTATCTGTGTGCCATGTGAGTTACAG TTGTACACTGCCATGTGAATTCTGGGAATTGAACTGAGTCCTCTGGTGAGCGGTAAGAGCTCTTACCCACTGAGCCATCTCTCCAGCCTCCTTTAAT GTTTTTCTAAAGAGATTTAAAAACAAAACAAAAAAAAAATCTCCTATGCTGTAACAAAGCAAGGAGGGTTTCTCTTCTGTGGCCACTTCGTCATGCA GCCCCATTAGTGATTGATCCTGTTCCATATAAAATACTGGTCTATACAATATTTCAAGTATATTTACTCTTTATTGCATTCCTTCAATTTGCATTAC ACAATATAATATCTTTTTCAATATAATTTTGGACAAAAACACAAGACATTAACTTCGTTGAACAAGAAACATAAATTAATTCATGTACGACTTTGTT GGGAGGAGAAAGGCAGAACCGCAGACAACAGGGACCACGGCGGTGGACAGGGAACCACGGTACTAGCCACGGGAATCACAGTTTCACAACACAATTC ACTCTTTCAAAGCCACAAAATAAGCCAGGGATGAAAACCCCAAACAAGGTATACAGACGGCAAGACTAGGAGATGATTTGCCTTCTACTGTGGGGAC AGTGTCAGAGTATCACCCAGGTGCCCCTGCGGCAGCAAGCCTCCCGGGCGGCTTCTGATGGCTGTCTTTGTGTTTGAAGCAGCAGCGGGGAGAGTGG CATGCGCCCTAAGACTCATCTCCACGAATGACGTGACGACCTAATTGCATTCCTTCTAACCCACTGATTAGGCAAACCACCCTCCAAAGGGCTCGCT GAGTTCCTCTTCGGGAAGAGGTGTGTTGAGTACGCTGGAATGGATATTCGAGGGCTGAGGGGAGAGGACTAGGGGTGGCTTGTTCTGCTGGAGAGTA GTGTTTTATTTATGTGCTGCAGACACTACAGATCACTTGAGATACAAGGAGGATGAATTGTAAGTCATCAGGCTGAGGAAAAGGAAGACGATGGCAC TAATAGGCCTCTAACGTCATCCTAAGGAACTGACCCACTTAGAGCCGGACGCTAATTAGAATTGAGAGGCTTGTAAATTATTTTAATTTTTTTTCTG TTTAGGGATGTACAGATTTCCATATGTATCTTTCATAAGGTTTTAACGGCATCTACCAAGTGGCTATTATTAGCATATCTCTTACCACAGAGCAAAT TAATTACACTCAGAGCATATCACAGCCACCCCAGGAATGATTTGACTTCCGATTAGAAAAGCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAAAACCAAACCCTATTC ACTAAGAAACACTCGAGGCTTCCTGTTCTCTCTACATTTTCCACCATTTGTTTGCTATTTGATGGGCACTTTCTAAAAGAAAATGGTCACATTCCGG GCACTTAAAAGCAGGTTCCAGTGAATCATGGACCATCAAGTTTTCTCTGCTCTGTGACAAGGAAGTCTTGTGAAGCAAGCCAAGGAGAGCAGACCAA CACGACAGCCTGCTTCCTTGCTTGGTCCCTCAGACCCACAGCACAGCGAGGGGCTAGTGCGTGAAAACAAGGCTATACAGGAAGGAAGGAAACCATC AGCGGGCTCATATGCGCTGGGGAAGACTTGGGACCTCGCAGATGGGTGAGCACTGCGTGTACTTACGCGCCTTCTTCTCTCATGAGGGCCAAGAATT TCCTCACACGGTACTCAGGATCCATCTAAAAAGCATCGGAAGAAAACAATCAGACGCGCGAAGCTGCCTTTTCTCCACAATGTGCTTCCTCCGCACC AGGGAGGCGCGTGGTCATGTGCTTCCTGGGTCGTTCAGAACCATGTCACCATTCCCTAGTTGTTGTTTCGAAGCATAATAAAGTGGGTTATGTTATT TAGAAGCCAGTGGAACTTCCCAACACGGAGAGGCTACTGGTCACTCACAGGCACCTCAGCCAAGCACCCCCCTGCACCCAGTGTTTGGTGTGAGGAG GAGAAGCACACCAGCCAGGTGTCACCACAACATAGATCGGTGGTCACTCACGGAGGGGTCCAGACATGCCTGGGTGCATTCATGGTGCTATAAATCA TGAGAGTTTAAATGCTAAAATTCATATATCTTATTGAAGGAGGAGGATAGAACCTGAGAAACCAAACTGAGGTTGATTAAGTGACCAAAATACAGTT AGAACTTTTTGTTTTGTTTTTCGAGACAGGTTTCTCTGTATAGCCCTGGCTGTCCTGGAACTCATTCTGTAGACCAGGCTGGCCCTCGAACTCAGAA ATCTACCTGCCTCTGCTTCCTGAGTGCTGGGATTAGAGGCATGCGCCACCACTGCCTGACTAGTTATGACTTTCACATACTCACTAACTGGGCATTC TTAGCTTTAGTGCCCTTCTGGTGACGCTGCCACACCTAAGAGAGCAGAGAGTGCTGTTGGCCTCCCCTCTCCGTACACCTGGCCTCTGGTAGCCCGA GAGTCACAGACTCAAGACAAGGTGGTTTGATCCGGGTGATGGTTCAAGTCACCATTACTAATTATCTCTCCTCGCTGGTCATTCTGGATCCTGTTAC TTCACTTCAAAGTGTATCATAGTTTATTGGCCTAGACTAGGGTGTGTGGGGATCTGGAAAAGAATAATCACAAACAAACATCTCTAATTACTCACTA TGAATTTGTACTGTAAGAAACACCTCACTTTTAAAGCATGTTGCAGGGCAGAAGTCTGCTGGCAAGAGGGAACTCCCTGCCCTCCAGGAGTGGCTGG GCTCGCAAGGGCTCAGCTCGCGCAGCCGTGGGCAAGAGTGCACTCAGACTCCCCTCCAAGCAGGCTGGAmGCGACAGTTCTGTCCCAGCAAAAAACA TGGAACGTAAGTTTCAAATGTATCAAAGTTAAGGGGTCAGACTACAAAGAACTAAGAAAAAGTGTGAACAGCTAACATGAGTCATTTTTTTTTTCCC CCTCTATGGGGACTAGAATTACACATGAATCAATTGTCAAAGCTTTTTTCTAAAATGGAACTGGCTGGAGCTCGCTGGAGTCAGTACATGCAGGTCT TCGCCCATTAACTCTATTTAATATGTGTGAGGAGCGACTTACTGACTTGCCTGTAGCTATGGAATTAAGAGTCAAGAGAAAGGGGAGGAAAAAAGCA ACCTAGATAAATGACTTTATTCCCTCAGGTGACATCCAGTCAGAGCACATCCTTAACACCGAGCAAGTTTTAACAAAATCGAGTCCGGCGAGCAGAG CGAGTGAGCATGGCTTCCATTCTGCTGAACTGCATGCCTCTCCACTCGGGCTCTGCCCCTGCTCCTGAGGCAGATCTAAAGAGAAGTCACTCAGCTG CTCGGAATCCATTTGACGTGAAGGGGTTCAAACTCCAGGCCTATGAAGTGTCAGTCGCTCAAGATTAGGCCGAGCGCCCCACTCTCACTTTCTACCT CACACACATAAGTATTAACTTGATCACTGCGCCGCAGGCATCAAAGGGAGAGGAGGCAGGGGTGGGGAGGAAAACTCGCATAGTTTCTCCTATGCAA TTATTTTAAAAGATTGAACTGAAACTGGAAAAAGAAGGGCAGAGCTGACTTCTGACAGATTTATCTTTTTTCGGGGACAAAGCCAATACACCTGTAT GTATGCCTTTACCAGGAATAAGCCTGAGCAGGGTGCTTAGTCTATGACAATAATTTACTACTCAAATGGAAAACTATATAAATTGACTTAAAAACAG TTGCTGGAAGCTTGGGAAACTTTTGGTTTCTGAAAAACCACAAAAATCTAATTTTAAATTGAGTTTATCAGAGAGAGAGTTAAGATAATTCTCTCCA TATTCTTATTTATTGGCCTAAGAGCCTCCTTCAGATGTGAAGCTGGGGAACCCCAATGTGAGCAGTGGGCGCGCCAGGGCTCCACAGTGACACACCT CCTCAGGTCTGGGGATGGCTCACTCCTCATTCATTCACTTCTGCTCCTTTCATTGTATCTAGTGAAATTTATTGAGCTCTCTAATACGTGCTGAGCT GGTCCAGGGGCCAGCGACAGTGTGTGGCAGCCCAGGGGTCTGAACACACGGAACTCAGTCTACACAAGTGTATTATGTACATGTGTGTGTACACGTT CGGGCACACAGAGGCAAGGCATTCCAGAAGGAGAGAGGGAGGTGCAGTCCACACAAAGAAAGTTCCAAACCAAATCAGTCTCATCTGCCTGTGCCTA GCAGCAGGCTGGGAGTCAGTTAGTTTGAGATTTCTAGGGCACTGGGCATGGCGGTATGAGCCTTTAATCCTAGCACTTGGGAAGGCAGAGGCAGGGA TGGTCTCTGAGTTCGAGGCCAGCCTGGTCTGTATAAAGAGCTCCAGGACAGCCAGGGCTACACAGAGACACCCGTCTGGAAAAACTAAAATAAACAT TTTTTTAGGAGTTCAGTGAGGGGAAACGCACAGTCACAGCCCGATCTGCACAAGTCGGCCGCATCCACACTTCCACATCTCCCAGAGCTCTTAGCCA TCAGTGCTGTCACATGCTCACCCTGAAGGACGGAGCCTCAGTAGTGAGAGAGATCGGGGCAGACTCACTGACAGACTCTTCTCCCATCTGCATGACA CTGGGGACACCTTGCTTCCCTCCTTCCCTTCCAGCCCCCTCTTCATCTTCATTGTCATCCTACAACATCCAGTCTCCCCTCACTGAAGGTAAAGTTT AAATTATCACCAGGATTTTGCACATCTCCTTTTATTGCTAAGTGCTGTAGATGTAAGCCCTATCCTAAGCTGTTCAGGGTCTCACTCCTTTTCTCTG ATTGTTAATAAGGACTATGAAATTGACTGTACCCAGGTCACCTCTCTGCAGCCTCCAAGATGTTGAGGAGCCTAGGGCAGGGGTGGGAGTGTCTTTT CCTCCTTGTTGAATGTCTTCCATGACGGGGCAGTTGTAGTTTTAAATTCGCTTTGAAGCCCTTTCTGATTTTGAGACCTAATGACTCTCTACATTAA GATTAGAAGTCACGCTCTGCTCTGCTCATTTATTTCTGAAGAGAAAGAGGAGAACATGGGTACTCCTGAGGCCTGGGAGAGGAAAGCAGGCCCTCCT GGTGTGCTACAGCCATTCCTGTGACTCACGCAGAGACGGGATCGCCTTACCTGCAGGGACATCTCAATCAACATTAGTAACTTCTTGATTCCTATCC AGACTTTCTTCCCCTTGACTTGCTGAGCAATTGTGGTGCGTTCCTTATCTTTGAAGTTGCCCAAAAGCTATAAAAGCAATAAACAACAATTAGACAC TTTTATGGTGTGCACACCAACATTCACCTTTAAGTGAACAGTGGGAGGAGCTACCTGCCTGGGATGAATTGACCCACCTAGTCCTGTATGACCATAA AAGACAAGGTCTTATTCTGTAGCCCAGACTAGCCTCAAACTCATGGTAATCCTCCTGCCTCAGCCTCCGCGGTGCTGAGACTACCTCATCTAGAAGA GATAAATCTTATGCTGTTTTTCTAAGGGACCATCACTAAACTGAGAGACGCGTTTCCTAGGGAAAACAGCTCCAATCTATGATAAATACAAGTTAAA CGTGTTAGCATTCCTTCCTGGGCGCAGTTCGTATGTGTCAAAGTACGCTGGTCTTTTCTCTTTCCCAACTACAACAGGGTGTTCAGACAGGTGACCC AGGCACACTTCTCATGCTGTTGGCGTCTGCTCTGTTGGGAGCCCACGGCAACTCTGAAGTTGTGGAGCCTTTAGGAGCCTCGCCCGACTCGACCACA CCGAATAACTTACATCACCTTTTCCATCAGATCCCATCTAGTCATCTGTGCACATTAATATTAATCAACACTCACTCGAAGACTCACTTTTTTTAAT TAAAGGCTTTATCATCTTCAAAAAAAAAAAAAAAAAAAAAGGAAACATTTCCACATTATAAAGTTGTGAGGTTTGGGTAGCGTTCTTTTCTTTTTTC TTTTTGGTAGTTCCAAGG MOUSE SEQUENCE—mRNA CCTCTTCATGATCGCCGGCAAACTTCCTCCTCGGCGCTGCTTCTAATGGAGCCCCACCTGCTCGGGCGTGCTACTCGGCCTCCTGCTCAGTGGACCA GGGTCCTCGCTGGCTACCCAATTTGGTGGTCCCTGGCCCTGGGCCAGCAGTACACATCTCTGGCCTCCCAGCCTCTGCTCTGCGGCTCCATCCCAGG CCTGGTCCCCAAGCAACTGCGTTCTGCCGCAATTACATCGAGATCATGCCCAGCGTAGCAGAAGGTGTGAAGCTGGGCATCCAGGGAGTGCCAGCAT CAGTTCCGGGGCCGCCGGTGGAACTGTACCACCATAGATGACAGCCTGGCCATCTTTGGGCCTGTCTGGACAAAGCCACCCGTGAATCGGCCCTTCG TGCATGCCATCGCCTCGGCTGGTGTCGCCTTCGAGTCACACGCTCCTGCGCTGAGGGAACCTCCACCATCTGCGGCTGTGACTCACATCAGTAAGGG GCCACCTGGAGAAGGCTGGAAGTGGGGCGGCTGCAGCGAGGACGCCGACTTCGGGGTGCTGGTGTCCCGGGAATTTGCGGATGCGCGGGAGAACAGG CCAGATGCCCGCTCAGCTATGAACAAGCACAACAATGAAGCAGGCCGAACGACCATCCTGGACCACATGCACCTAAAGTGTAAATGCCACGGGTTGT CCGGCAGCTGCGAGGTGAAGACCTGCTGGTGGGCCCAGCCCACTTCCGTGCCATTGGCGACTTCCTCAAGGACAAGTACGACAGTGCCTCGCGAGAT GGTGGTGGAGAACACCGTGAGTCCCGAGGCTGGGTGGAGACCCTGCGGGCTAAGTACGCGCTCTTCAAGCCACCCACCGAGAGGGGACCTGGTCTAC TACGAGAACTCCCCCAACTTTTGTGAGCCCAACCCAGAGACGGGCTCCTTTGGTACCAGGGACCGGACTTGCAATGTCACCTCCCACGGCATCGATG GCTGCGATCTGCTGTGCTGTGGCCGGGGCCACAACACGAGGACGGAGAAACGGAAGGAGAAATGCCATTGCGTCTTCCACTGGTGCTGCTATGTCAG CTGCCAAGAGTGTATTCGCATCTACGATGTGCACACCTGCAAGTAGTGAGCCAGGGCACTGGGAAGGGGTAGATTGTGCGGCTGGATCCATTCATCG AAGTCCCATGAGAAGCAGGATCTAGATCCAGGCCAGCCTTCGGCACTGGCCAGCAAGGAGCATGGACTGTTGCCAGCTGCATGTGGTAAACGACCTG GACCCAGCCGGCCTCGGACGGACGGGCGGCTTCTTTCTCAACTAACGTCTCTCCCCCTGCTCTGGATGGTGTACGGCTTTACAGAGGGGCTTTCTTT ATGGTTTTACCAGGGTCTGCTGGGGACAGACTCGAGGCTTACCTTTGCACATGTTAAAGAAAATAAAAATGAAAAAAAAAAAATCTACGCAACAGAA CAGGCTGGGCTAGTGTGAGCTCTTGGCCTGGTGGGAAGGACAAGACCATGGCGAGATTCTGTGTCCAAGCTGCCTCTACTCGTGACATTCCAAGATG CCTCTGAGGTGGGAACTGTGAAGTAGGACAGAGCCCCGCAGTCCCCTCTTGTCCGTCGACTCCCATTTAAATTGGACATACCTTGTCGTTCTGAGAA AAGCCATAGATAGGTGTAGCTGGGATGTAGTGATGGGGAGGCCCCTGGCCAACAGTGGGAGCAAGATCTTGAGTTTTGAAGACCTCAGAGTTCTGGG CGGCCTGGGAAGCCATCTGCAGAACAGAGTTCGTTGTGGGCTCCTGTTTTCGCTAGCCCTGTTCTGCCCTGGAGCGACAGTCAGATCTCCACGCCCC TTTCTGTTGTTCTACAGTGTCCACCTTTACTACGCGTTTTTTTTTTTTTTTTCATGATGACCTTGTAAATAGGTCAGATGTGGAGGCAGGTCTCTTC TGGCTCCATCCACCACACCCAGAAAGAATGGGCTGCTCTGCCCTTCTCAGCCTTGCTAACCAGCAGACACCGAGGAGAGCAGCGGGGCACCTTAGAG AGCAATCTAAACATGGTTGGCAGGTGGGGAGGGTAAAGAGTCCCACTTCCTTTGTGTTAGAAGGCAGACTACCCTGCGTCCTTTTCTCCCATTGGCT GAAGTAACCAGAAAGACAAGAGATCCTTAACAAGCCCTTCTTCCCACTTGTAAAAGGGATAGCCTATCTCAGTTCCCAAGGATCTGGATTAGATAGA TATTCAAAAGAGGCAAGCAGCGAATGGAGGCAGCTCCCAGCTCTGTTCCCGACGCATGATGGTACTGGCTGGGTTTAGTAAGGTGGTGGGGGCTGCA CGGATCAATCCATCAACTCCGTCTTAAGGAGAATCAGAAAGAGGAGATAAAATGGGGGAATGGGGCAGAACAAAGAATTTGTCCTTTCCCGCTTCTG TCTAGGGTCTGCTAATGCTGGCTTGACGAGGGGTCAGCCACTTTTTCCTGTTGTGCAGTTGGCTTGCCAAGCAGGCTCCAGTAGGCGCATGGCCTGC ACTCTCTACCATGTGACCATGAGCACTGCTCTAGGGACACCTCCCATCCCTTCCTAGACCCCAAATGCCCCTTCCCATCTCTCCTTCCAGGAAGTTG GAAATCAAGTCAACTGGATAACGCTTGTGTGAGACACTTGAGCAGAACGGATACAACAATTTACAAGTCTCTTCATATCTATGTATTCTATATTAAA AGTGATAAAGTCATGTTTCCGGGGCGTATTCAAGTAGCTGACAAGTAATTATTTAATAATAGTACATGAGCGCATTGTAATTATCCTCGCCATAGTC AGGTAATAGCATCCAATGGGAGGTCCCTACCAACCTGCTGTATCCAAAGTTTTGTAAAAAGTTGTAGAAGTTGTTGATCTTTTTGATTTTATATTCA AAAAGTCTCTTTTTATAAATATTATTTATTATACAATGTATATACCTTTGAGTTAACTAAGATTATATATTATATAAATATATATATATT MOUSE SEQUENCE—CODING ATGGAGCCCCACCTGCTCGGGCTGCTACTCGGCCTCCTGCTCAGTGGCACCAGGGTCCTCCTGGCTACCCAATTTGGTGGTCCTGGGCCCTGGGGCC AGCAGTACACATCTCTGGCCTCCCAGCCTCTGCTCTGCGGCTCCATCCCAGGCCTGGTCCCCAAGCAACTGCGCTTCTGCCGCAATTACATCGAGAT CATGCCCAGCGTAGCAGAAGGTGTGAAGCTGGGCATCCAGGAGTGCCAGCATCAGTTCCGGGGCCGCCGGTGGAACTGTACCACCATAGATGACAGC CTGGCCATCTTTGGGCCTGTCTTGGACAAAGCCACCCGTGAATCGGCCTTCGTGCATGCCATCGCCTCGGCTGGTGTCGCCTTCGCAGTCACACGCT CCTGCGCTGAGGGGAACCTCCACCATCTGCGGCTGTGACTCACATCATAAGGGGCCACCTGGAGAAGGCTGGAAGTGGGGCGGTGCAGCGAGGACGC CGACTTCGGGGTGCTGGTGTCCCGGGAATTTGCGGATGCGCGGGAGAACAGGCCAGATGCCCGCTCAGCTATGAACAAGCACAACAATGAAGCAGGC CGAACGACCATCCTGGACCACATGCACCTAAAGTGTAAATGCCACGGGTTGTCCGGCAGCTGCGAGGTGAAGACCTGCTGGTGGGCCCAGCCCGACT TCCGTGCCATTGGCGACTTCCTCAAGGACAAGTACGACAGTGCGTCCGAGATGGTGGTGGAGAAACACCGTGAGTCCCGAGGCTGGGTGGAGACCCT GCGGGCTAAGTACGCGCTCTTCAAGCCACCCACCGAGAGGGACCTGGTCTACTACGAGAAGTCCCCCAACTTTTGTGAGCCCAACCCAGAGACGGGC TCCTTTGGTACCAGGGACCGGACTTGCAATGTCACCTCCCACGGCATCGATGGCTGCGATCTGCTGTGCTGTGGCCGGGGCCACAACACGAGGACGG AGAAACGGAAGGAGAAATGCCATTGCGTCTTCCACTGGTGCTGCTATGTCAGCTGCCAAGAGTGTATTCGCATCTACGATGTGCACACCTGCAAGTA G HUMAN SEQUENCE—GENOMIC TGCCTGCCTTGGCCTCCCAAAGTGCTGGAAATACAGGCATGAGCCACCGTGCCCGACCTGGGCAGAACTACATTCTGGATGCATCTTAAACCTCACC TCAACCCTACACCCTCCCTTTTGTTGTTTCCTTTCTCCCCACAAGTCATCTCAGAATGAGGCTCCCAGCTCCAGGCTCCAGTTGCAACCTCACCCCC ACCTAGACAAACCCTCAAATCAAGAAAAAGAAGCCCTGGCAGGGCGTGGTGACTCATGCCTGTAATCCCAGCACTGTGGGAGGCTGAGGTGGATGGA TCGCTTGAGCTCAGGAGTTCAAGACCACCCTGGCTGGGCAACATGATGGAACCCCATCTCTACCAAAAATTTTAAAAAATTAGCTTGTTGTGGTGGT GTTTGCCTGTAGTCCCAGCTCCTTGGGAAGCTGAGGTGAGAGGATCATTAGATCCTGGGAGATGGAGGTCGCACTGAGCCAAAATTGTGCTGCTGCA CTCCAGTCTGAGTGACAGAGTGAGACGCTGTCTCAAAAAAAGAGAAAAGAAAAAGAAATCCAAAGGAAAAAAAGAGAGAGACAGAGAGAAAGGAAAA GAGAAAAGAAAAGAAATTTCTGTTGGCCAGGCCCGGTGGCTCATACCTGTAATTCCAGCACTTTGGGATAGGCCGAGGTGGGCGGATCATGAGGTCG GCGGATCATGAGGTCAGCGGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAATAAAAAAAAATCAGCTGGGCGTGGTGGTG GGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGGGAATGGTGTGAACCTGGGGCGCGGAGCTTGCAGTGAGCCGAGATTGCACCACTGCAC TCCAGCCTGGGAGACAGAGCAAGACTCTGCCTCAAAAAAAAAAAAAAGAAAGAAATTTCTGTCTCAAAAAAAGAGAAAAGAAAAGAAAAAGAAATCC TAACACTCATCCATCCTTAAGTAAAAGCAACTCACCTTGTAAGTCAGTCTCCACATTTAATCCAACTACCCTACACTAGACATGATGGGTGAGGAGG ATACAGATAGTTAGGAGGCCTTTGGCTACAAGTAACAGCCTCAAGTGGGCTAACGAACAAGGAAAATGTATTATTTCATATCACAAGAAGTTCCAAA GCAGGACTCCTCTGAAGGCAGTTAGTGTCTCAGCAATGGTGTCAGAGATGAAGTTTGTTTCTCTCTCTTGGCTCTGTCTTCCTCTGCCGGTCAGCTT CATCTTCAGGCAGCTTTCCTCATAGTCACAGAATGGCTGCTGCAGCTCCAGGTATCCCAACCCAAAACAACAATGTCCAAAAGCAGGGAAAAGATAT TTCTTACTGTGTGTCATTTTAAGAGCCCCAAAAACTCTTCCCAGAAACCTTCTGCACCCTTCAGCTGACCTCCCTCAGGCACATGTCAGCCCAGTTT AGGCCAATCCCTGGCAAGCAGAATGGGTCCCCGTGATTGACTTAGATCAGTCAGGATTTACCTCTGAGCAAGGTAGGGGAGGAGTAAAGACCAGAAC AAACTGGGGGCCTCTGCCATCCTGGAGGAAGGGACCACCAGCAGTGTGAGCTACACTAAATCTAAACAGAAGCCTGTCTTCCAGAAGTTCAAAAACA GCAGCTGAGGCTGGGCATGGTGGCTCATGCCTGTAATCCCAACACTCTGGGAAGCTGAGGTGGGTGGATCATTTGAGGTCAGGAGTTCAAGACCAGC CTGGCCAACATGGTGAAATTCTATCTCTATTAAAACTACAAAAATTATCCAGGCGTGGTAGCTTGCATCTGTAGTCCCAGCTAGGAGGACTGAGGCA GCAGAATCATTTGAACCCAGGAGGCAGAGGTTGCAGGTTGCAGTGAGACAAGATCACTCCAGCCTGGGTGATAGAGCGAGACTTCATCTCAAAAAAA AAAAAAAAAAAAGAGCAGCTGATTGCCACAGAGGGAGGGAGTGGATGCTCACCGATCATTTTACATGTCCCAGGTGCCATTTCAAACACAGCAGCTA TCACTCTGCTGAATAGGCAATTGTCTTTTGAGACAAGTGTTATTATACCCATTTTGCAGTTGATTGAAGCAGGTACAGAGAGGTTAGATAATATGCT CAGTGTCACATAGTAAGAGGCAGAGCTGGGATTCACTGGGGTTGTGGTAGACCTGGGCTCTAACGCAACCACTCAGAGAGGATTTCCCAGTCAGACA TGTGAATCCCCATTCAGGCCTTATCTAGAAGCCAAGACAAAGGTGCATAAGAGGTGGGTCCTGCTGGGATGTGGGAAATGCCAGGCAGATGTCCCTG CTTAGCCCAAGGGCCCTCCCACGTCTGTGCCAGCTGTGCCTAGGCCCTTGCCAGTGAGGCAGCTGTGACCCCATTCCCAGCCCACTGGGCCTCCATC CATGTGATTAGGCTCCCAGGACTCAGGGCCCATAGCTGGCCACCCTGAGGTCCCAGCAATGACAGCTACTGGCCATACTGGTCTGTGGAGAAGGTGG TTAGTTGGCAGAGTTCTGGAAGGTGCAAACCAGGACTTCACTAGAAATTTCTTCACCATCTCCAAGGATATTATCAGGCTTGTTCTATTCTATCTCC CTAATGTGCCCCCACAAAAGTCTTCCCCGCAAGACCCCTGAGATGGAGAGAACTTCCACACCTCTGTTTTGTTTCGTTTTGTTTTGTTTTCTTGAGA CAGTTTAGCTCTTGTTGCCGAGGCTGGAGTGCAGTGGCACGGTCTTGGCTCACCGCAACCTCCGCCTCCTGGATTCAAGTGATTCTCCTGCCTCAGC CTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCATGCCCAGCTAATTTTGTAPTTTTAGTAGAGACAGGGTTTTGCCACATTGGCCAGGCTGGTT TCAACCCCTGACCTCJGGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCCACCATGCCTGGCCTGGTTTTGTTTTTTTA AGGAAACATTTACGTATTTGGTCCTCTGATGAATGACTGTCCCCAGCAGATGGCAAGTTCCTTGCAGGCCAAAACCTGGGCTGCTTTTGCTCATCAG TGCTCAGCTGCCAAGGGGCAGCTGCACACAGAGTTGCTCCATGAAGATGCGTTGAAGAAATGGACCAGGTGAAATTCACAGAGCACCTACTGTGTGC ATCAACCGGAGCTGGGTTATAAGGAAGAAGGCAGACTCCTTGAGGGTTGTCCCATTCCTCGTGGAGCCTTGTCCACAGCAGGCATGCAGTCAATGTG TGCGATGAGAAATACAGACACTTTCCGCCCTCAGAGCCCAGGCGGAAGGTGGGGGCCCATCGTGACTAAGGTTGGAGACAGAAGAGACCAAAGATGG CTCCAAGCCCCTCCTGGGTTGCAACCAGGGCTCCCTCCCCTTCCCTGCCTGCTTATGTCCCATACACAGGGGAGTGGAAGGAAAACTCAGGAGCTCT AGTTCCAGGTGACTGAGAGAAACCGTGGCAGCCACACACAGAGGTCTGGGTCTAACTCCTCAGGTTGGATCACAGCCATGCTAGGAGCTGGCCTTGG GTTAGAGCCCCAAAAGCCTTGGGCAGGCCAGCCATGTCCAGGGATGGGGCTCAGGGTTATGAGGCAATGGCAGAATAAAGGGGCACAGAGGGAGGCT GAAGAGAAAGAAAGGCAAGGAGAAAGAGGTGTGGCACATGGCTGGAGAGGCAGCACGAGGGGCCACCAAGCCCCAGATGCCCCCATGTGGCAGTGAC TTCCCAACAGGCTGCCCACCCTTAATCTCATCCCACTGGAGGCAGCACAGGGTCCTATGAAAGGGACACAGGAACCAAGCGACAGAGCAGGGTAGCT GGGGTGGGTTGGAGTTGTAGGGGCCAGGGCCACTCAAGATAGGGGCACTGAGGACCCTGAGGGGCCACAGGGAGCCCAGACCTGAGTCAGTGGCCCT TCTATCTGAGACCTCGGCCCTGCCTGCTCCCTCTCCTCTGGGCCCATCATCAACAGTGTTTTCGAGGGGGTGCTAAGTGCTGGATCCCTCACCACTG GGGGTTCAGCAGTCTTGTGGAGGGAGTTTCTTTGTGGAGATTTCACAGTTGGAGACGGACAACATATGCAAGAAACTGAGCAGATATGTCTGCTATG TAGTATGTATAATCACCCCGGCATGGGGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGTACCACCTGAGGTCAGGAGTTCAAG ACCAGCCTGGCCAACATGGTGAAACACTGTCTCTACCAAAAATACAAAAATTAGCCAGGCATGGTGGCGAGCGCCTGTAATGTCAGCTACTTGGGAG GCTGAGACAAGAGAATCACTTGAACCCAGGAGGTGGATGCTGCAGTGAGCCAAGATCACACCACTGCATGCCAGCCTGAGCGACAGAGCAAGACACC GGGCTAGGGAGTGGCAAGGGGTCTGGAGGGGCCTCTCTGAAGTGGATATTTTGAAGTGGGTCTTGGAAGGGGACATCAGACAACATTATCCCGGATA AATCCTTCTGGAGAAGGCTCCTGGGCGCCTGAAGGGGGACTGCTTAGCAGACACTGACTGGGGCAGGAAGAGAGACCTGAGAGAGAGGCTTACTCCT TGCCTCAAGAGAAGAAGGAACCCAATATTTTGTATTCACCATCCGCAGTCTGGCATTCCGTCAGCACCATTCTCATTTAACGCTGACACGCTCCCTA CAAGGTGGAAAGTGTTATCTCCACTCCACAACCGAAGCCAGGGACTCAGAGATGACAGGCAACCGGCCAGTGCCCCCACCCCACCCCATTCCCTCCC TTCTAAAGGACTTTCACCGCAAATCGCTTTCCAAAATGCTCTGGGGAGGCCAGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGACCAA GATGGGTGGGTCATTTGAGGTCAGGAGTTCAAGACCAGCTTGGCTAACATGGCGAAACCCTGTCTCTACCAAAAAAACACAAATTAGCTGGGTATGG TGGTGCATGCTTGTAATCCCAGCTACTTGAGCGGCGGAGGCAGGAGAACCACTTGAATATGGGGAGGTGGAGGTTGCAGTGAGCCGAGACTGCACCA CTGTACTCCAGCCTGGGCGACACAGTGAGACTCTGTCTTAAAAATATAGGTCAGGAGTTCGAGACCAGCCTGGCCAACACGGTGAAACCCTGTCTCT ACTAAAATACAAAAAATTAGTCAGGCGTGGTGGCGGGCACATGTAATCCCAGCTGCTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGGAGG CAGAGGTTGCAGTGAGTCGAGACCGCGCCATTGCACTACAGCCTGGGCAACAAGAATGAAATTCCACCTTTGTATATATATAATATATAATATATTA TATATAAATATATATAATATATTATATATAAATATATAATATATAATATATAAATATATATAATATAATATATATAATATATAATATATAATATATG TGTTTATTATATAATACATATTTATTATAAATACATATTTATTATAAATACATATTTATTATAAATACATATTTATTATAAATACATATATATATAT ATACATAAACTGAATGCCCTGGGGAGCTAGAGCTATGACAGGAGGAACTACTGCCACAGGGAGTJTCCTCTTGGTGCCCACAGCGGCCCCCTGTGAT CTCGGGATCCAGGAAGAACTGGTCACATCCGCCTGCCGCTGGCAGCCTCCCATATGTCAGCGGAAGAGGGAGGCATCCGCAGGGTGGATCTGGCGGT GCCCCAGTGCGCCCTGGACCGGCATCACCTGGGCCCGCTCGCCCTCCGCCTGTCTGGAGAGGAGAGGGGAGCCTGAAGCCATGCACCCCTTATCCCC AGCTAAGCTCCGGGATTGCGAGGTAGATTAAGGGCATTCACTCAGGAGGGACCTGCTTAACCAAGATCCTCCGAAATCCGGGCTGCTCACCAGCAAC CAATTGAGGATGCCGGGCCCGCAGGGAGCGGAGTGGGACCAGGCGCGACCCCTTCCTCGCCTGCTGACCTCCCGCCTTGCTATCAGCACTGCCGCCC GGGGGCGCGCCCGCGCCGCTGGGCTCTGAGCCGACCTCCGCGTGCACCTGCGCTCCTTTGTGTGTTAGATTAACATCTGGTGCTTACCTACTATGCG CTTACTCGGTGCAGGTCAGGGGCTTCCTGCATTTCCAGGATGCAGCCTCTATGCCAGCAAACTAGGCTGGGCAGTGGAAAGAAATCCGATTTACTCC TGCGCCCACCACCCACGCTAGGGCCTTCCTGCTTCCAGGCTCTGCTGTCCAGCCTTCCAGTGGCCTCTAGGGAGCTCGCCTAAAACCGCTCTGCGGT TCCTACAGCTCCTAGGAGAAAGTTAAACGCCCTCCTCTCCAGGTCAGAGGCCTGGAGCCCCCTATGTGCTCCCTTTGCACTGTTCCTCCATAAGCCC CTGTGGTGTTAGGCCTTCGGCCCTTCGCACTTCCCCACCTGCTTCCCCGCTGCAACGGCTTCGCCTCTCCCTTTACCCCCCCAGGTTGGTCCGGCTC CCGACTCCCGCCTGGCAGCCCCAAGACCTGTTTCAAGCAAAAATGAATGGCACAGTGCCTGGATCGGAGATTTCCTCCTCCTTCCCCGCGACAGACG GGTAGCCCCATGAGGGCGGGCGGGGGCCTGGCCACCGGATTCTTTGTCTACACGGTGCCTCCGCAGGGGGTCCAGTGGAGCCTCACTGAATACACAG CGGCAGACTTTGAGCCCCGGGGGAGTGCACATCAAAAGGAACCTCCGAGCCAGCTAGAGAGAGGGGTTGGGTTGGGACTGGGGTCCCCTTCCCAGGT CTAAGGTCCCACACATTCACACACACAACAAAAGTGCTTCCCACGTGCCACCCCATGTCCCCAGGACCCTGGCCCTTGCTGCCTCTCTGCCCTCTAA TCCAAGAGACCACCCTTCCTTTCAGGGCGATGGCCTCCTGGTCCACCGGCTGATGCCTCCACCCCGCCCTCCCTTCCTGGTCTTGGAGTGAATTTAA CCCTTTCTCCACCTAGTGAACCACCCTGGGGCTTGGGGTACCTGTTAGAGAGAGGGTGTTTCTATCTGTGATGTGTGGTCTTGGGGCGCCCGCCCTC CCCTGAGAGAAACCATTCCTGCGTTTCCACCCGCGGCAGCGCAAGGGGTGCAGGAGGAAGGAAATTAAACCTGTGTTGAAGGAAGGACACCTGGGGG AAAGGAAGGGACTCAGGCTCCCCTTGTCTGAGGAGCTTTCAAGTGGCGGAAATCCCCACACACACCTCCATTCACTAGGGGCCTGGCAGGGCCGCTG GTAGGTTCCAGTCCTCTCCTCTGTCACTTCCCAGGCGCACATGGCCAGCTCCTAGATTCCACCCTTCAACCCACTTGTTTCCTGCCTGATGCACATG ACCTGCGTCTGAGTTCTCCAGGCTGCCTGGAGGAGGCATTCAGGTACACATGACCCCTCAGGGAATGATGTTCTTGCCCACAGCACCCAGGATGCTG GCTGGGCATATCTCAGCCAACACACACTCCCACCGACAGCCTCGGATCTTTTGCTCCCACCTCACAGGGTTGGCACCTGTGGAGTCTTGAGGCCCAG TAATGACCCCAAGAAGCCATCAAGTCCAGGCCCTGTCGCCCCACCATACTGCATCCACAGTGGTGTCTGAGTGGCCAGGGAAGGTAGCCCTCCCCAG CTCTCAGCACCACTGTCATGGGGCTCTGGAACTCCCGAGCCCTTGGGCAGGACTCCAGCAGGCAGCTCTGATCAGAAAGCCACCTGGGAGCCCTGTG GGTGGGACAGGACTCCAGGTAGGACCTAGCAGTCCTCCATCCAAGAGGGAGGTATGTGGAAAGCTCTCCACTGCCAGAGCCTTGGTCCTGAGGCTCT GCATTCATGGCAATGGTAACCCTCTTTCCAGGTGAATCAGAAACAGGGCACCCCAGAATCAGCCCAGCCATGAGGAGCATCTCTAGGGATCCCCATC TCTGCAGCCCCCACCAGGTTCACCACTCCTGGTCAGGTTCACGATTTTTCTTCGCCTTGCAGCTCCTTGGTGCTCTCCGCCTCCCCCCTGCCCCTTT CTTCCTCACACCGGTGGCTCAGCCTCCCCCCGACAGTTTTCTTGGTTTCTGTCTCAGCGTCTCTCTCATCTCTGAGCCCCTCTCTCTCTCTCCTCCT CTCGGATTCTCCTTTTCCTCCCCTTCCTTCCTCTCTTTCAACCTCCCCTCCCACCCCCTCCAGTCCAGCAATGGGCTGGGAACGCAGCAGGAGCCAT GACAAGCCCAGGCGGCTCTCCCGACCGTTGGTGCCCCCGAGGCGATTTCCCCGCGCTCCCTGTGCCGGCAGCAGCCGCGTGCGGAGAGGGCTCGCCG ACCAGAAGGGGCAGCAGGTTGGAGCTGTGGGTACGGGGGGCTCAGATCAAAGGCCAGGAATGTCTGGCCCCCTGGCGTAAGACTTCCTTCAGCCATG GCCCTCACCTCGTGGAACGCCCGCCGTTCCAGGCCTCTGTGGGACTCGGGTCGGCTCATTCTCTGCCCTTTCTGCCACAGTTCCCTACACAGCGGTC CCTGCTCCCCACCGGCAGTGCTTCCTTCACCCCAGACCGGGGCTGCGCAGAGTCCTGGTGCCTCAGGTGGCCTGGGAGGGGGCCTAGGGAAAGGCAC CCAGGTGACCGGGCGTGAGTCCCCAAAACCTGACCATGATGTCAATACCACCCAGGGCTGAGACCTAATTCCTCGCTCTGGAGAGGGAGAGGAGAGG AAGCAAGCCCGAAGGGGGCCTGGAAGGACTCCTTTCCTGTGGGGAGGGGTGGGTAACTGGAGGCATTTGGTGTCCGCACAGGGCAAGGGCCTTTATC GCCAAACCCCAGGCTGGAGCTCCCTATCAGTAGAACCGGGGCCTCAGGCGGGACGGTCGGGCAGTGAGGGGCGCTCCGGAGGGCAGCAAGGTCTTCC AAGGACCTGGGCCGCCCTCGGCCAGAGCTGCGCGTTTCACCGGTCCCTGATGGTCCAACCGAGAATCCCACTGAGGCTGTGGGTCACGCCTCCGACC CGGGCCAGAGGTCGGGCCTGAACCCCTCAAGGAGGAGAAAGTGACCCGACTCCGAGAGCAGGAAATGCGACTGGCCGCTGGTGTCAGTTGCAGGAAA TGCAAAGGCAGCAGGAGGTCCCGATACCGATCTGATCCCTGACAAAAGACTCAAATGACACTCGGCTCCGTCCCCCGGCGCCGCCCGCAGCCAGACC TTCGAGCCTCCGCGGACTTTTCCGCACGTTCCTCGGACACCCGGGAAGTGACCTCCCGCGGCCAGGACGAGAGGCCAGAGAGCGGGCGGACTCGGGA GGCTGGAAGCTGGGAGGGGTGCGTTCCCCCACCCTCTGATTCCTGACCTGCCCGAGCGGGGCTTCTGGAAACATCCCTGTGCTTTCTACCCTCGATT CCTCGCGGGCCCACGTCCCAACGGGTCACGGTCCCCGCCAGCAAAGGAGCCACCCGTTCATGCCCACGCCAAGCCCTCGCCATGTGAACGCCCGGGT CAAGCCCCCGCGCCCTACCCTGGCCAGCGGGGGACCGCGGCGGTAGCAGAGGGTCCGGCCCACCGCGTCCCCCCGAAGCCCCGCGGCGTCCGGGGGG CGCGGGCTTTGCCCAAGTTTGCTGGGCGATGCCCTTCCCGGAGCCCGAGTTGTGGGCCGGGCGGGAGGGGCGCGTGATTGACAGGCTGAACTACAGA CTCATCTCTTACCTTAGGCCGCGGGCGCTGATTGGCTGCTCGCTGACATCCTCAAACCCGGCTGCTCCGCGCTGGGCTCGGGAGGGGGGCGGCTCCG GGTGGAGGTGCGCTTCTGACAAGCCCGAAAGTCATTTCCAATCTCAAGTGGACTTTGTTCCAACTATTGGGGGCGTCGCTCCCCCTCTTCATGGTCG CGGGCAAACTTCCTCCTGGGCTCCTCTTCTAATGGAGCCCCACCTGCTCGGGCTGCTCCTCGGCCTCCTGCTCGGTGGCACCAGGGTCCTCGCTGGC TACCCAATTTGGTGGTAAGACTCGCCTCTTGTCTGCCCGCGGCCCGGTTTCTCCGCCCCGTCCGGGGAAGGTGGGGGCGCCGGCTGGGGGTGGGCCG CTGCAGGGCTGGGGCTCCTCTCCTCGCCTCCCTCCAGCCCCCCACCCGCCCACCCCTCCTGGATTTTCTGCTGGTGTCGCCTTCAGAATCCAACTCC TGGCTCCTCTGATAATCACCATTTTCCCTGCTCCCCGCTGCAGGGGCTGGAGGACTTTTCCCATCTCAGAAGGTTTCTTATTCTTAGATCCTAACCC TCTGCCCGTCCCAATCTAGAGGCCCCCGAAGACCCCCCATTTGCTTGCAGTTGGGTTTCTGGAAATCCAGCACTGTCCCTGGGGCCCAGCCACTCCT CTTCTCCATTTTGGGGTCTTCATGGGCAAAACCATCCTGTTCCTTCACTGCCACCCCACCTCTGCCGGCGCCTCCATCAAGAGATTCCCCATAATAA CCCCCCTTTGCCTTCCTATTTCAGACCCCAAAGGCTTCAGGGCTCCTCCCGGGGCAGGGGAGTGGGTGGGGGGATTTCATCAGATTCTCCCCACCGC TCTAGATTCATCTTGAGCCTCTGAAGTGAATATGGTATTTGCTGATCCGGGATGCCATTGAATTCGGATTTTATTCATTTCTTGCTTGTCCACCCTG GCAAAAGGGGGGTTCCTTGAAAATGTGTTGTCTGGGAGGGGTAGGCTTGTTGTTCTTTGACCAAAAATCCAATTCTCCATGTCACATTTCTTCCTTT TGGAAAACCGAGGACCGAGGAGAAAGGGAGAGGGAAGGGAGAATTCCGTCCCTGAGAAATGTGGATACAAAAGACATTTTAGTAAATAAGACTGGGA AGCCGGGAGCAGTGCTTGGGGGGGGCTGTGCGTGTCTGGGGGGCCTGGGTGAGGAATAAACATCGCTTTGGCAGCCCCAGCTCCAGGAGTCCCCTTG TTTTCCGAGCGGCCCCATCGCCGCTCTCCCACCCTCCGCAGGTCCCAGGGGCCAGAGGGGAAGACACTGAAACCAGTTCTCTGGTTTACACTCCGCC TCTCCCCAGTCTCCAGCCCCCTACATTCCGGAAAACTTTTAATTAAAAGAATCTTCCCCTCCTGGACATAGGAGAGCCTTGGCCTGGGCGGGGAGGT GAGGAGGAAGAATTTGGGATCTGTGAGTGAGAAGTGGGCTGTGGCCCCCGGGGTGAAAGTCAGAAAGAAGTGCCACCACGGTGCGGTACCGCCTGCA GGTCCCCAGACTCCCTGCCTTTCGCCAACCCAGAGTCCAGGGTAGGAGGAGCAGAGACAGCGAGACTTGGGGGCCACACCCCGAGTCTTCCAGTTGT TTGGGGATGGCAGCATTTGTGTCTGGGTGTTTGGGGCTCCTGGGAGAGAGGGTGGGGACATGGCCAAGGGTCTCTGTTTAGAGGGTGCTAGGAGTTG CTCCCAGGACAGCCAGCCAAGGGGAAGTCTTTCTTCTGCCCAACCCACACTTTTCCGGGGGGCTGGGCTAACCTGAGGCTTCCAGCACATAAAGAAG TCCATGGGGTGGCCAGGGCAGCCAGGGACTTCAGGAAGGAGGTTCGGCCAGTCTGGGGAAAGGCTGCTGCCAACACCAGTCCAGCCTCACCCGGCCA TTCCTGACCCTCTTCCCATTCCCGGGCCAAGGCCATGCCGTTTTTCGCCTTGCTTTCGCAGAGACTCTGGTGGGTTGGGGGAGGGTAGGAAGGAAAG GTTTGGCGGCCCATAGGTGGCAGGGACTGAGGAAGAGAGACCAGTCTCTCCGGCCCTATGAACTAGAAGAGGGCACTCTTCCAGTTGGTGTAGATTC TGGTGTGAAATGGTATCTTGGGGACCATCTAGATAGGGATTGCCCAATAGGAAGAAACGCTGGGGAAACCTGGAAGGTCAAGACATTGGCCCTAACA TAATGCTAGACACATGGCTTGTTTGGGAATTTGGTGGGGGACAGGAATGCTGCTTTGTCTAAGCCAAGGAGAGAGGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGCGTGTGTTCTGGGTCTATGACCCTAAGAGGTGTTTTCTATACACCAGTGTGTCTCTGTGTGCAAAAGTGTTTGT GCCTGCAACTGGGCTACTATGGATGTGAAATCGTGTGGGCGTGTTGGGGGATCCATGCCCACGACAGGTTGTGCTGTGTGTGTCTGCACACGAGTGT GAGCAAGTGGCTGGTGCTGTGATGTGTGTATGTACATGTGTAAGAGACAGAGAGAAGTCTAGAAGTATCTTTGCCCATGTAAAGGTCAGAGCCTGTG TCTGCCTGTGACGCTGGGCTTGACTGTGTTCATGACTGGGCATGTGAGTGTGTGTGTGCGTGCGTGCGTGTGTGTGAGTGTGTGTGTGCGTGCGTGT GTGTGTGTGTGTGTGTACGTGCGCGCGCATGCCTTCATGACAGTGTGGGGAAAGCCCCACAGATGTCTTTGTGCATGAATATCAGTGCTCATGGCCA TGACCTGATTGTGCTTGTATGGAGGAGAGTGAGCCTCTGTCCATAGCTGTGTGAGGCTGTGTCTAGTCCGCCTGTTTTTCCTGTCCCCCAAGGTGCT GGGCCCAGGGCTGTGTGGCTGTGAATATCTTTGCAGACATCTACCTGTGGGTATGAATGACACCTGAGCTTGGGTGTTTGGTGGGCAGCCATGGGCC TGGAGGGAAGGTCCAACAGGAAGCAAAAGTCTCACAAGGTGGCTGCAGGGGGCACAGCTGGCCAGGGATGGCAAGCTAGAGAGGCAGGGGCACAGGC TTCCTTGACACCAGCTTGTCCTGTCTGTCCAGGCACTAGAGTCACTGGCCCTTCTCTCTGAGGTTGTTTTTCTTTGGTCTTGGAGCTGGGGTGGAGG GTGAGTCACCTTCTCAGGGTTAGGGCTGGGGCTGTAGGGTAGATGGGCCTCTGATTCGTGATCCCATTTCTGCCCCCACTCCCCATACCCAGCCCCC GCCTGGCAGTCAGATTCCAGTACTTTGAGCATCTAAGCCCATCTTGGCCTGCCCTCTTTGGCCCACCCAGCTCATGCATTCCCCAGGAAGGATTTAC AGGGGAAGTCATGTAGCTGGGATTTCTGTCCACGCGGACCCTCAAGCATGACACCCTGAGTCCACACTGCTCAGACCCCAGTCCTGACAGAAGGTTG ACCAGAAGGGACAGCTCTAAGGGGCCTCAGACTGACACCCCTGGAAGGAAGAGATGTTCTCCAGGTAGTGACAGAGCCGGGACAGGAAACAACAGCA CTGATTTCTCGAATTCCCCTTGTCAGTCCCAGTTAGCTCCTGGTGGAGAAACTTGTCTTTCTTCTTCTTCTTGGGGGCGGTGGGGTGGGGGGATGAA CCTATGTTATTAGGGCCTAGCCCAGCACCTGCTACATTCCAGCGATGGACGTGCAGATGGAGGGGGCCTGCTGGAGATCAGGAGCTCACCCTGCCGC TGTGTGACTGAGGACCAGTGGCCACCCATCTGGGTCTGCTTCCTTACTCTTCACCCAGGAGTCCCCAGCCTGCCCTGCCTCACAGCTTGGGTGAAAA TGTTTTGCAGAGGACAAGGGCAGTGAGCTGGGAAATAGCACACCTGAGTTCTCGCCATCCCAGGACCCATCCTCCCACTCGAGCACCTGCCTAAGAC CTACCTCAGTTTCCCCATCTGTCAGATGTCCTGCTGCCTCTCCCACCCACTCCCACCTCCACCCACCTTTCAGAGGCTTGTGAACATGTTCAGTCAA ACCCCGTGGGGGTCAGTGGGCTGGGCCCAGGGAGGCACCTGGAGACTGCGGGGGAGGAAGGCCCCAGGCCAGGTGTTAACACTTGTAACAGGCAGGA ATTACAGCTCGCTGGGCTGGGCTGGCTGGGGCTGGTGAGGAGCTGAGCTAGCTGGAGT3CTGTTGATCCCACAGACAGACAGACAGACAGACAGATG GGCAGATACCAGATCGGATGGCCAGGCTTTAACCGGGTGGTCTCCCTTCCAGGGCAGACCTTTCCCTGGGGGGGATATGGCGGGGAAATTAGTCCAG GTCTCTTGGAAGTTAACAGCCCTCCCGCTCACCCCGCCCCCATTATGGGTGGGGCTTCGGAGTCCAGAGGGAGCAAAATTGGTGGCCGATCTGTTGG TATTCTTCCGATAGGATCACATTTTGCTTAAAAAGAAGAAAACAGGTCAAACGTTATAATAATACCAAGAGCCTGAGCTGAGTTATGTCCTTAGAAG AACCTGCTGTAATATGTATGTGGATGGCATGGGGGAAGGGGACGCTCTCAGGGAAAGTTCTAGACTCTCAGAGCATTTTGTCAACAGCTCCGGGGCC AAGAGGTGAGAGATGGGTGGAGTCTGAGTATCACCCCCACCTCCACCCGAGGGATCCTGAGGGCTTGGGTCTGTGATGTCTGCCCTGCAATTAATCC TGGCCTGGTGGGAAGACCTTTGGCGATGAGGTCAAAAGAGGCAGGAGCTGGACTTTGGTGCCAAGTCCTTTAGGAGGTGCTTGCTGCAGCTTCACCA GTGGCAAACCCAGCCAGGCCCTACCAGGGCCCACACTCTGGCATCTGGATACATGCTCAGGTCACTGACAAAGGTGGAGAAACTGAGGCAGACGCGA GGGCTCTGGGTGGAAATCTCCAAAGAATGCACTCAGCCTAGCAAGCATCTCTCATCCTCCTCACTACAGAACTTAATGCTAATAAACATTAATGGTA CTTGGGCAGATGTAGAATTGGAAGAAGTCTCTCCTTGGTCTGGGCAGGAGACAAGGAGCCAGGGGATAAGGAGCCAGGGGATGGCACAGGAAAGGTG ACTTATCACAGAGGAGGATGCAGCTAACAAACCCTTCCAGGGAAAAGGAAGTGGGAAAAAGGAAGATTTTTCTGGTCTCAGAATGTGATGAGCCAGG AGTTGAGCAGAACCTTTTCCACCTACCCTGATGTGAGCCACAGAAACCTTCTCCAGCTGCCAAGGAGGGCAAGACATCCTCCACCCCTCATTCCTAA CTCAGGGAGGAGGTATGCCTAGCCCCACCCCCACCCCCCGCCAAAGGTTAGAGCCATCCTGATATTACATCTGTACATCCATGTTATCTTGTATGCT GGAAAATGGTGAGAGTGGGGAGATGGAGAGACCTATGTCTGAATTCCAAGTTTAATACCAATGGACCCTGTGACCTAGGATGAGTCCCTTCCCTTCT CTGGGCTTCATTCAAGTCCCTGCCTCCTTCTGGGCTTCATTTTCCTTTACCACATGGAGGGGTCCCTTTTGCCTCTCAGAGTCCCAGGGCTATGACA GGTTCTGGGCTCGTTGCTGTGAAGCATGACACTCTACTGCACACATTCCGGGCCTGTATTAGACAGTCCACCCGTTTCTTTCTGTGGCTCCATCTGA CCTAAATCGCAAAGAGCTGGCTGCCCCACTCCTGCCAAGCCAACCTGCTTGCACTTCCAAACCTCGCCCCAAACACTCCCACTCTTCTGGAGCCAGG CCATCTGCATTCACATCTGGCTTTTTCATGTACTACCTGGGTAACTAGGGCAAGTTAACCTCTGCAAGCCTCAGTTTCCTCATCTGTTAAATGAGTG TAATGATTGCCTCTATTTCATAGGGTTTTGAAAATGATTGAGTGAATACTTCTTAGAATGATACCTTGCATACAGGAAGCATATCGATGTTAGCTAT TTTCACCTCCTATCTGCAAGCTATTGGCTCACTGAAGCCCTGGAGCCAAACTTGCGTCTTCCAAGAAGCCCTCCCAGATTTGCCCCACCTGGCTCTG TTTTCCCCTTTTCTTCTTTTTGCCTGTTTGCCCCACAGTGCTTTAGCTTTATTCTTAAGTTGAGGGTGCTGGGCCAGGCTAATCTCACTTCAGCTCT TTACCTGCTCAGGAAGGGGAGGGCAGGGTAGAGAAGGTTGCTGGAGTGTCCCCTAATCATTCCCCGACCCCCACAGTCTGCCAGACTCTTGCTGGGA CCTAGAGCCAGGGGGCTGGGCACAGAAGGGGTGGGGGAGGCAGGCTTCCCAGGGGGAGTGGCACCAGGGCCGCCCAGAGCAGCCTGAGCAGAAGTTG CTTCTCTAGGAGCTGAGAGATGATTCAGAAGGTGATTTATAGTCGGAAGGCAGAAAGCTTGGCTCCTGGCAGAAGCTGCTGCTTAATTACATTCTTG GGGCGGGGGTAGGGGGGTGGAGGTATGTGTGGGGAGGCAGCAGGGGCCAGACTTCTGCCTCCTCCCCATCCAGGCCCTCCCTGTCCCTTTGGCTGTC CCGGCTCTAAGCAGGGTCCTTCTTTATCCCGCTGCCAGAGAGGGAATTCCCTGCTCTCAGTGAGAGGCTAGGCCAGGATTGCAGGAATAGCTTCTGG GAGTGGAGAAGGTGGGAAAAGAGGAAGGAAGCTGGATCCCATCTCCCGGGACTTCTCCAAGGGAGACTGGATGGCGACGGGCTGGAAAACGTGCCTT CTGGGAAGGAGCACTGGGTCTCCTCCCTGCTTCTGGGCAGCGGAATAGCTAAGGCACCTGGGCAGAGTTGAGTTTCTTTCTTTCTTTCTTTTTTTCT TGAACAGAGCCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACAATCTTGGCTCACTGCAACTTCTGCCTCCCGAGTTCAAGCAAATTCTCCTGC CTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCGCACCAGGATGCCTGGCTAATATTTGAATTTTTTAGTAGAGATGGGGGTTTCACCATGTTGGCC AGGCTGGTCTCGAACTCCGACCTCAGGTAATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCGCACCCTAGCCAGAGTT TCTAGAATCTTCTGAGAGGCAACTCCACGCTCTCCTTCGGGCACCCTGTCCTGCTGCTGCCTGGGAGGGCCTGCCTGCAGGTTTGCTCCTTTTCTGT TGCTCAGGTCTCAGTGGGCCATGGGGGCTGGAGAGAAGGTCCTGCGCTAGAGGCTGAAACCCGGTTTCTTCAGCGTTAGGCAGCCTGTCCCTCGTGA GCACAGTGGCTACCCCAGGTGCACAACGGTTCTGCCAGCAGGCACGGCCCCATACCCTCATGTCAAACTAATATCTCAGAGAGTCACCCCAATGCCG CTGGGTGCAGCTACAATCACTTCCGCGCCATTGACAGGAGCCCCCATTCTGTTTCCATACCTGCTGAGTTGACATCAGCATTTCCCATATTAACACT GACCCATGCAACAACCCGCCCGATGACACGTAAGGCCGCTTAGTTCCCTGCATCGCAGCCGTGAATCCCAAATCCCTCACTGCTAGTTCTTAAGGCT GGAAAGGTGTAGGGCGGGCAGGGGTAGAGTTGCTGAAGCCAGTAGTGTCGATTTATCTGTTTGCAGCCTGGCCTGTACAGCCGGGAGGAGTTGGCAG GGGTCAGGATGGGGACACTAGACAGCTCTCTGGTTCCCCCTGAGGCGGGCCTTCTCAAAATGGCCTCATTATGTGTGTGGAGTGAATTCCAGAAATG TCAGGCACACCCATACATCTAGGGAATGAAGGAGATGCCAGAGCGGGCTCTGGGGCGAGAGGGGCCAGTGTGAGGAGGGTGGGCGGCTTCCGTCAGG GAGTTAGGGCACCTGAGACCTGGCTCTGCCACCATCTTGATATTAGGCAACTTCCTGAACTGTTCTGAGTCTCAGTAACTAGGAGAGTTGGATAAGC TGCTGGCCAAAGACTTCCAGCTCCGAGATTGCAGTCATGGAGGCTGTATTCCGCGTTCAGGTCACCCAGCTATTTGGACCATCTGTGCCTGGTGGAG GGGGTGGTCACTGAAAGCTGGTCTCAGGGAAGGGTGGGGGGTGCAGAGCTCTAAACTCTACACACAAAGAGCTGTGAGACAGTGGATGAGTCTCCTC CCTCCCTCAGTTTTCTCATCTGCAAATTGGATGATGATAATAACACGACCACCTGCCCTGCCTGCTGCAGGGCCGTGAAGAGCTTCAGGGTGGAATA ATCTTTGTGGGCATGCCCCGTGACCAGTTGGCCTCAGACCTGAGGCCTCTGTGCCCTCTGCCAGGGGCTCTCCATTGAGCATCAGGACCCCTACAGG AAGGAGCTGAGGACTCCTTCCTGAGGACACTTGGGAAGTGTCAGGTTCTTTCCAGAGAAGTTAACTATCACTGTGAGTCCTAGAAAAGAGGAATAAG AAGGCTGGGCATGGGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAGTTTGAGGCCTGCTTGGCCA ACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGAGCCTGTAATCCCAGCTACTCGGAGAGGCTGAGGCAGGA GAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCACCACTGCCTTCCAGCCTGGGCAACAAGACCAACACTCTGTCTCAAAAAA AAAAAAAAAAAAAAGAAAGAAAGAAAAGAGGAGAGGAATAAGAGCTAGTCCCTGCTCAGACAGTGCTAAGAATGGACCTAAGAGCCCCCCTGAGCCT CTGAGCTTGAGGAGTTGATATTTCCAGCAGAGGAAGAAGTGGGGCTGGACAGGGGAGTCCTCAGCTCCTTCCTGTAGGGGTCCTGATGCTCACTGGA GAGCCCCTGGGAGAGGGCACAGAGGCCTCAGGTCTGAAGCCAACTGGTCACGGGGCATACCCAGGTTCACAGCTCAGGGCATGGGGCTTGGTTATCC TCCTGGCCTAATGCAAAAACCACTGGCCAGACCCAGAGTGAGATTTCCAACCAGGGACACATGGGAAGATGTAGGTGGAGGTGAGGGGGGCGAGGGC AAGGGCTGCCAGCTGGAAGGGGCTCTGCTGAGGCCTGTAGTCATCAGGGAATCCTAATGGCCTGGGTTAGGCCTAGCAAACTAGGAGACCCATCACA AGCCATTCCCTCCAGCTCGGCTGGAAAAACTGCGAGGACTGAGTGTGTGTACGTGTGTGTTGGGGAGGGGGATGGGAGCAACAGGACCAAGCACCCA GGTCTGTCTGGAAGACCTTTCTGGGAAACCTGCCCCTGGGCACAGAGTCCCACTTATCTGCCAGAGCCAGCTGGGCCGGCAAGGAAAACCAATCTCG CAGGCCCATTAGGAATGCAAATAGGGCTTGTGCTGTGAGTGAGCAGGATCCCGCCTCCTCTCCAGCTCCCACCAATCATCTTCACAAGGTGGGATTG CTGAGGGTGCCACTCCCCTGCTCTGACACCTCCCATGGCTCCCCTCTTCCTATCTGGTACTAGGCTCCCTATGATTTCACTTCTGTCCACCTGCGCC AGTTGTAACTTTCACAAACCCCCTCGATCCCCCAATAAACCCACTTCAACTGGAATACTCACCTCTTTGCTTGTTCATTGAAATACTTCCACCTCCT CTCTCTGACTTTAAAAGGCAGCCCAACCTGGGGCCTGTTGACCTGGGGTCAGTCTGCTCTGCGCTGCTCAGCTCGGACCCCACTTGGCTCAGGTCAT GTAGCTAACAGCCCTGAACTATGGAGGGTCCTTAGAGGGTCTCTCAAGGTGGATGGGCCCCTCGACCTGAGCAGGCTGCTGTCCCAGGAGTGGAGAT GAGCCTTTTCTCCACAGTGTCAATTCCCCTGGGTTTCTTTTTCTTTTTTTTTAATCCACGTTCCACTTGTAAACGTTTCCTATTTGTGTACTATTTC CCCCTCCATGTTCACCAGTTCACACGATGCTTAAGTGTCTAAGTCATTAATTTTAAGATTGCAATTGGCAGAAGTTGTTTCTCTATCTAGGAACAGG TTAATACGTTTGTTGACCATGTGCTATGTGCTGATCCCCATGCAGACATCATGATTTATCTGAATCTAATTGTTGCCAGTTTATAGATAGGGAGTCC CACAGTGCAGCCTGGGCATGGCATGGGAAGCCCTGAGCCCACACCCTGTTGGACCTAAAGCCTTTTTCCTTCTACCACCATTCAGGCTCAGTTGTGG ACTTGTTATTGGGGTAAAAATTTGCTTGTTCATTTTCTACTTTGTTCCCCAAAGGATGGTTTTGAGACAAGTTTACACTTGACCTTCCACTCAAAGG CTGATGCTTTGGGCTTATAGATACTATTTGTGAACGTCTGGGAAGTCTCTTATTTGGGGATGTGTCCTCTTCACTGGCCACCTTTCCACAAGCCATC AGGCTGTCCTCAAGCTGGGATTGCACAGTTGCTGACAGCAGTGGCCATGTGAGGATTTTGTTGCCCCTGGGATGGGTAAGGGGCGACCTTGATCAAA TCACTGCCTCCCGGGCCTCAGTTTCCTCATCTGTGAAACAGAAAGGGTAGCGTAAATGACCTCTCAGATTCCTTCCAGCACTAAGCTCTTTCCTTCT ACTTAGTCCTTTTTGCTGCTTTGCATCTGGTCTCCATCATATACGTGCTAGAAAGCAGCTGGGCAGAATCTTCTTTCTTGCCCTAGTCCAATTCTTG TGTTGGTATCTCTGAAACAGCCAATTGTTCATTTCACTTTTACAATTCGACCTTCAGCTTTATTTCTCCCCGAGGAGCCAGCATGCTTTCTCCTTTC GCTCTTCCGTTTTTATTTTGTTATTGAATCTGATGTGTTTTCCGTCATCAGCCTCTTGAGGGCAGACATGTTGGAGTCTTTGTACCTGGCCTGGGCA TAATGGATCCTCAATAAAGACTTGTCTTTGGGATACACATTTGCTGTCAACCTCTTCAAATCCTTTCTGGAAAGAAGCAAGGCACATGCGAATTAAA AAGCAAAATAAACATTGCTCTGGGAGGGAGTTGGTCCTGACTGGATAGTTTTGAGTTATGAGAATTCCAGTCTGCTTCTGTTTCTTTTTTTTCTGTT TATTTATTTACTTAGAGATGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAGTAGCATGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCA AGCAATTCTCCTGCCTCAGCCTCCCAAGTACCTGGGATTATAGGCATGCGCCACCACACCCAGCTAATTTTGTATTTTCAGTAGAGATAGGATTTCA CCATGTTGGTCAGGCTGGTATCAAACTCCTGACATCAAGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGAGATGACAGGCGTAAGCCACCAGGCC CGGCCTTCTTTCTGTTTCTTTACTGTCAGCTTTTCCCCAAGTCTACAAAGGTCTTGTCTTCAGAGAAGTCGCCTCTTTTTTTTCCTCCATGATCTTC TCCACTCTAAAGCTGAGGTTGGTTCCTAATCTTCCTCTAGGGACTGTCTCTCGTTCCTGGCCAATGACTATGTCCACCCCTACCCCTGGCTCCCTTC ACAACTGGTTCCTCCCACCCTCCCTTGCCTTGGAAGCCGACGGTGCTATTGCCACCATTCCACAGGTGACGCAGTGCCCAGGTAGCACCCACCCTCT CTCCAACAGAGCTGCTCCCGTCCCCAGCAGCCATCGTGAGGGCCAAGCCCCACTCTGCAGATGGAGCCCCAAGGAGGAGCAGAGGGGAGCGGCGGCC AGGGATCTCCCCATTCACCCAGCAAGGTGTCCTCACAACTCTAACCGGCTCTCCCCTCCCCTCCGCTTCTGCCCTTGGGCAACACATGTGCAGGTCA CCCCACCCAGTCCCTGACTTCGGAGGAGAGAATGTCTAGCCTCAGGCTGGGTGGTTCTCCATCTTAACTGAAGCTTCCATAGGGGATTCTGGAGCCT TTCTCTGCTACCAGTAAGGATGGAGTCTGTGACCTCTGCACTGTCCTGGAAGCTAAAGCAGCCTCGAGAAAGCAGCCTCTTCATCCCCATGTTACCT GTGAGAAAACTGAGGCTCAGCTGGGCGCGGTGGCTCACGCCTGTAACCCCGGCACTTTGGGGGACAAAGGCAGGCAGATCACCTGAGGTTGGGAGTT TGAGGCCAGCCTGACCAACATGGATAAACCCCAACTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCACGTGCCTGTAATCCCAGCTACTGGG GAGGCTGAGAAAGGAGAATCGCTTCAACCGAGGGCTGAAGTTGCGGTGAGCTGAGACCTGGCCATTGCACTCCAGCCTGGGCAATAAAAGCGAAACT CTGTCTCAAAAAAAAAAAAAAAAAAAAGGAAAAGAAAAAGAAAAAAGAAAAAAAGAAAACCGAGGATCACAGGACCCAACCAGGAGCTGTAAGGAGC CGGAAGCAAGTGGGCGGCTCCAGTGGCAGCTAGTAATTCCTCGCTTATGATGTCCCfTGGTATCACATACATTGAGGAAACAAAGCACACACATTAG CTCATCCTCCCGACAACCCCAGGAGGCAGAGACTCTTGTTATCCCCATTCTACAGATGAGAAACTGAGGCCCTGAGGCACCATTCCATTGCCGAAGG CTCCATGGTTGGTAAACCCCAGAGCTCTAAACAAGAGACAAACTGCCTGAAGCCAGGCCCTTCAGTGACACCACACCACACCACATCCAGGAAGTTC CTCCTTAGATCTGACTTCAGTCTTTCCTTAATCCAGGCCCAGGTTTTCTTCCTGGGGATGTGAATATCACTGTCAAGTTTCAGTTTGGTTTGGTTTG AGACAGGATCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTACAATCACAGCCCACTGTAGCCTCAATCTCCTGGGGTGAAGCTATCCTCCTGCCT TAGATTGCCAAATCACTAAGACTACAGGCAAGCACCATATGTGGCTAATTTTTTTAATTTTTATTTTTATTTATTTTTGAGACAGAGTTTTCACTCT TGTCACCCAGGCTGCAGTGCAATTGCAAGATCTTGGCTCACTGCAACCTCCACCTCCCCGGTTCAAGCGATTCTCCTGCGTCAGCCTCTCACGTAGC TGGGATTATAGGCGCCCGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGATTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTG ACCTCAGGTGACCCGCCCACCTCAACCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACTGTGCCCAGCCTTTTTTGTTTTTTTTTGTAGAGATAG CATCTCCCTACATTACTCTTGCTTGAACTGGACTCAAACAATCCTCCTGCCTCAGCCTCTCAAAGTGCTGGGATTCCAGGGGTAGGGTTCCAGTTTG CACTTGAGGACCAGGGTTCGTCTCATCCCTGAATCTTCCTGTGTCTGGAGTTGGTTCCTTCCAGTGGGTTCGTGGTCTCACTGACTTCAAGAATGAA GCCACGTACCTTTGCGGTGAGTGTTACAGGTCTTAAGGACCCCAAGAGTGAGCAACAGCAAGAGTTATCCTGAAGAGCAAAAGAACAAAGTTTCCAC AGCATGGAAGGCGACCCAAGGGGGTTGGTGCTGCTGGCTTGGGGGTGGGGGGGTGGGCGGGGAGGCAGCTTTTATTCCCTCATTTGTCCCAGCCCAT GTCCTGCTGATTGGTCCATTTTACAGAGTGCTGATTGGTCCATTTTACAAACCTCTAGCTAGCTACAGAGCACTGATTGGTGCATTCTTACAGAGCA CTGATTGGTGCATTTTACAAACCTCTTGTAAGACAGAAAAGTTCTCCAAGTCCCCAGTTGACCCAGGAAGTCCGGCTGGCCTCATCTCTCATTCCTT CTCTAGAACAATTCCTCCCAGGTGACCCATCCTCTACTCACCTTTAACTACTTGTTCTTCCTCTTCTGATCTCTTACCAGCTTTTCTACAACTTCCT GCAAGTCCTATAGCCACAGAATTGCCTTTAAATCAGGGAAAGAGGGGGCCTGCCATCAGCTCTCTGATTTAGAGGCTTCCGTCTGGTGTCTTACAGC ACTTCCCTTCCCCATAGGGCAGGGAGTCTGGAATCCAGCATGCCTGCCCTCAAGAGGCTTATGACGGAAACACATCAGATTAAATAACAAAATAAAA AACAGGCTAGTTGTGGTGGCTTGCGCCTGTAGTCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCACTTGAGGTCAGGAGTTCGAACCAGCCTGGC CAACATGCTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGTGGCACGCACCTGTAGTCCCAGCTGCTGGGGAGGCTGAGGCAGG AGAATCGCTTGAACCCAGGAGTGGTGGTTGCAGTGAGCCAAGATCACACCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAA TAAAAATAAATAACAAAAACAGAAGAGCAGGATCAAGGTCAAGGAGAAGACAAATATGCAAGTCAAGGTCAATGCAGGTGCAAGGATGGAGCTTGCC CTGAGTTTCCTCACAGCCAGGACATAAGGGAAAACACGCTTTACCTGAAAGGAGAAGGCATGCTGGGTCCTCAGGGAGAAATGCCCGCCTACAGCCT GTGCCCACCCTCTTCAGCTGCGCCATGAGAATTTAGGCTCCTGGAGTATCTGGCCCAGACAGCCGTGAGCCTGCTTCCGGGCTCTGCTGGCCTCTGC CTGGGGCCCATTCTGCCAGGGCAGGCCACACTGCCTGTGGCCAAGGGCTGGTCAAGGGAAATTCATTTGCAAGGGCTGTGGCTGGAGCTTGAGGGTG TGGCTGGGGCCTCCAGCATGGGATGCAGAAGGGATGGGCAGGCTGCAGGCCTGGGGCTAGATCTCCCATGTCACCATTGTCTAGCGTGAACTTTATC AGGTAACCTAGCCCTCTAGGTGGCAAGTAAGGTTTTGCCAAGATAGGAGGATAGAATGATTGTTTAACTTTTTTTTTTTCTTTCTTGAGACATAGTC TTGCACTGTTGCCCAGGTTGGATTGCAGTGACACGATCTCACTATAACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTCCCTGAGCCTTGCGAGTAG CTGGGATCATAGGTGTGCACCGCCACACCTGGCTAAGTTTTGTATTTTTAGTAGAGACAAGGTTTTGCCATGTTGGCAAGGCTGGTCTCAAACTCCT GAGCTCAGGTGATCTGCCTGTCTGGGCCTCCGAAAGTGCTGGGATTACAGGTGTGAGCCGCTACGCCTGGCCAAGTGATTAACTTTTTAATGAAAGT ACAGGAAAAGACGTAAACTGTCTTTCCTCTGCTTTCACCCTGCAATAATTGGTACAGAAGACTTCTGTGACCAAATGCGTGCATACACCAAGCAAGC TGTCAATTCTGCGGCAGACATCAGCCAGCGTCCTCTAATCCAATTCAATTCTGATGATCTCCACCTGGACATAGCATCTGATCCCATAGGTTGAGGT CTTAGTTCCCAGGACAGCCTCCCACTTCCAGTAGCAATCCCAAGCCCCAGGCTGCTTTACATGTGCTCCTGACTGACCTGCTATAAATCAGGGTTCC TGTGACTTCCTCCTTGGGTTCCATTAATTTGCTAGAGTGGCTCGCAGAACACAGGAACACACGTTTACTGGTTTATTATAAAGGATATTACAAGGAT ACAGATGAAGAGGTGCATAGGGCGAGGTATGGGAGAAGCTGCACTGAGCTTCCACGCCTTCCCAGGCACACCACCTTCCAGGAACCTCCACGTGGTT CCGCTATCCGGAAGCACTTGAACCCTGTCCTTTTGGGCTTGTATGGGGGCTTCATTCCATAGGTATCATTGATTAAACCATTGGCCACTAGTGATCA ACTTAATCTTCAGCCCCCTCTCCCCTTCCCAAAGGATGGGGTTGGGGTTAGGGTTGGGAGTCCAACCCTCTAATCTTGGCCGGGCACGGTGGCTCAC ACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCATCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCATCTCT ACTAAAAATACAAAAAAATTAGCCGAGCATGGTGGCAGGTGCCTGTAATCCCAGTTACTGGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAG GCGGAGGTTGCAGTGAGCTGAGATCACAACACTGCACTCCAGCCAGGGAGACAGAGTCAAACTCCGTCAAATAAATAAATAAAAGAAAAGAAAAGTC CAACCCTTTAATCCTGCTGGGTCTTTTGGGGTAACCAACCTCAATCTTGAAGCTGCCTAGGGGCTGCCAGCTCTTCCGTCACGCTCATTAGCATACA AAAAGACATCACTTTGGAGTTTCTAAGGATTTTAGGAGTTGTACGCTGGGAAACTAGGTCGAAGACCAAATATATATTTTATAATATCACAAACATG CGTACAGGCGAGCACACAACTTGTCAGTGTACAGCTTAATGAGCTGGATAGAATATCTTATGTTTAACAGTTTGTGAACCTGGCATGAAACTTTTCA ATACTGGGCACATGGTAGATGAGGCTTCGTTGAGTGGTCTCAATGCTACAGCCAGGCCTTAGGCTTAGGCGGGGAAACAGTTCCACTAGGGTCGAAC TGGCACAGCATCGGGAAGAAGGCTTGCCTCCTCTAATGTGGCTGCATCATCTCCATCCCTCCCTTGGCAGACCCACAGTGGCACTGCCCTCCCTCAC AGCTGTGGTCACTTACCTCCAAGTCCCTTTTTGTTAAACTTGGACCATGTTTTAGCCTTTCTCAGCCTCAACGGATCTTCTTTTCTGATCAGTTTAG TCAGTCTTATTTTTATTTAATTTAATTTAATTCAATTCAATTCAATTTGGTTTTCAAGATAGAGTCTCGCTCTGTTGCCCAGAGTGGAGTGTAATGG CGCAATCACAGCTCACTGCAGCCTCCGCCTCCCAGGTTCAAGCTATTCTCCTGCCCCAGCCTCCCAAGTTGCTGGGATTACAGGCGCCTGCCACCAT GCTCGGCTAATTTTTCTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCCAGCTCCTGACCTCAGGTGATGTGCCCACCTCAG CCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCATTTGGTCATTTTTTAAACGGTCTAATTAGGAGTGCAGCAGCAGCAGATAT GACTGTGTTGTTGTATACTCCTCAGCCTGGCCCCTGCCGCCCTGCACCCGCTCCTCTCCCAACCCCAACATGGGTAAGCACATGGGCCTGGGTACAG CAGTCCTGGACTCTAGATGGTTCTGCCTTTTTATCTGGGTGGACTTCACCTCTCCAAGCCTTGGTTTTCTCTCTGCAAAATGGGGATAACGAGGGCT ATTGTGAGGATGAAAGGATATAACGCATGTGAGACTAGCACAGGGTCAGGTGTGTACTCAGTGAGTTAGACACACATTTTGCTGACATTAATTTCAT GTTACAGTCTGCGTTGTTCTCGTGCACACCTCACTTCTCCGTGCCTCTGTGCTACCCCCTGCCTTCTCTTGGGATGAGTACAAACTCCTGTTCGGTC TTGAAATCATAGTTCAGCCATCACTTCCTCTGCGCAGCCTTCCCTCAGCACCGCGGCCCCAGCAAAGGCCCTTCTGAGCACATCTATTTCATGGACT AGACTGTAAGTCACCTGTGGGCAGGACCAGTTCTCCATCATCTTTCAACCCATACCACCAAACATAGCACAGGGCACACAGTGGATCCTCAAAGACA GGTTGTGGGATGAAAGGACACTGTTGAGAGTCACCTGCTGGTCCCAGACTCTTGTCTCCCTGCTCCAGCTGGATTCTCATTGCCTCTGTGATGCTCT GCCAGGAAGACCAGCTGGTACTTGTTGTGTTTTTTCCTGTATTCTCAGATACCTCTTCATGTGCATCTGTCTTGTCTTCCCAGTGTAAGAGTCAGCC CCTGAGGGCAGGGATTCTGCTCTGTAGGCCTCTGCATCACTAGCGAGCCTCACACATCATCCTGAGTGTTGCAGGAGCACAGTTAGGAATTCTGTTA TCAGGCCAGGCATGGTGGCTCACATCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACCTGAGGTCAGGAGTTCTAGACCAGCCTGAC CAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGGGCAGCTGTAATGCCAGCTACTCGGGAGGCTAAGGCAGG AGAATCACTTGAACCTGGGAGGTGGAGGCTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGTGACACAGTGAGACTCCATCTCCAATAA ATAAATAAATAAATAGGAATTCTGTTAGCACTTGGCCCAGGAATCAGACTCCTTCCCAAGCAGGCTCCAGTTCAGGCTCAGCTGGTCCCCACTCTCT GGGACAGCACTCCCCTCACTCTGTGATCTCCCAGGAAGTCCGGCTCTGGGCATCTTACCTTGGTGTGGGGAGGCAACATAGCACTCCAGAAAGAGGG TAGGCTCTGTGACAGAACCACCTGTGGTGCAAATCCCAGATGTCCACTTCATAGCTTCTAGAACTTTGCTTTGGGTGGTTGCTTAAAAATCTGAGTC TCAGTCTCTTCCTCTGTATAATGGGAATAAAAAATATGATCTCAAGGTAGTTGTGAGGTTGAAATGAAATAACAGACAGAAACTGGCTAGGCGCAGT GGCTCATGCCTGTAATCCCTACATTTTGGGAGGCCAAGGCGGACAGATCATTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACTC TGTCTCTACTAAAAATACAAAAAGTAGCCAGGCATGGTGGCGCACACCTGTAATCCCAGCTACTCAGGAGGCTGAGATGGGAGAATGGCTTGAACCT GGGAGGCGGAGGTTGCAGTTAGCTGAGATGACACCACTGCACTCCAGCCTGGGCAACAGACTCCATCTCGAAAAAAAAAAAAAAAAAAAAAAAGTAG AAATAATAGAAACTGAGTTGAAGGTGAATCATTAAAGATGTTCTACAGGTCATCTAATGTAGCAGGGTTATAAAAATATTCTCTCCCAGGCCAGGCT TCTTTAGAGCAGAAAGATCTGAATTCCTTCCAAAACAGAAAAGGCTGGCTTCAGGGAATCCCACACACTTTATGTTGGTTTGTCCCAACCAATAAGC CTATCTGAAGAAAGAAGCGGGTGGGGAGGCATGTGGCAGAAGTCTGTGACTTGGTGGACAAAAGGCAATGCAGACTCTGGCATGACCTTGCGTTCTG GTATCCTGTTCAGCCAGAGTACTCACAAAGGCCTCCAGTTCTCAGGAAGGGAAGGGTGAATTAAATGTGGTTAGCTATCAGGGATTTTTTTTTTTTT TTTTTTTTGAGACGGAGTCTTGCTCTGTCACCAGGCTGGAGTACAGTGGTGTGATCTTGGCTCACTGTAACCTCCGCCTCACAGGCTCAAGTGATTC TCCTGCCTCAGCCTCTTAAGTAGCTGGGAGTACAGGCACGCACCACCATGCCTGGCCAATTTTTGTATTTTTAGTAGAGATGGGGTTTCCCCATGTT AGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGCCCAGCCTATC AGGGATTTTTATGGGGGTTCCAAGGAGTGGTCTGTGTAGATTTTATATCACCCTAGTTAATGGCTGAGGCACTGGCTGTGTAAGCCCTTGCTAAGCA CAGTGAGTGAGTGTGGCTGGAAGTGCAGGAGGCCTGGGTGGGATGCAGGCTGATCCAGGGCTGGCAGTCACTGTGTGCATCCAACCTTTAGGCGAGA GAGGGCTGCTAAACTCTGAGAAGGAATTCAGGGTGAAGAAGAGCTGATGTGCCAATGGTATGGCTGGCACAAGCCTAAGCAGATACCAGCTATTCTC CTGCAAGCTGATCAAAAATATTTTTXTTACATAATACTTGACATATACAAGAGAACAATCATATATATTAGACATGATGACAGAATGAAAACCTGAG CCTCACTATGTCCCTGAAGGACCAGACCGTGACTAGGCCGTCGTGTCCATCTGTGGGTCCTCCTCAGCCCATTCCCCATCTCCCTCTAGATGTGACC ACATCCTGAATTTTACCTATTTATTCCATTACTTAAAAATACTGGTTTTTGGCTGGGCACAGTGGCTCATGCCTGTGATCCCAGCACTTCGGGAGGC CGAGGCGGGAGGATCACCTGAGGTCAGGGGTTCGAGACCAGCCTGGCCAACATGGTGAAGCCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTG TGTTAGCACACGCCTGTGGTCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAATCCAGGAGGCAGACGTTGCAGAGAGCCGGGATCACGC CACTGCACTCCAGCCTGGAGACCCTGTCTCAAAAAAACAAAAAACCAACAAACAAAAAACTGGTTTTCCCAGGTAATAATGCCTAAATGAAATGTTT TATTTTGCCTATTTTTAGCATTATAAAAATGGTGTTATACTGCATGTGGCCCTCTATGTTGAGCTATTCTCTCTCTGCATTGTGTTTCTTAGTTTCA AACTGTTCCTGGATCTTGCTGTAGTTCTCACATGCTCACAGTTGCATTATAGTCCATCTTTAGAATATACAGTTTATCTATTTTGTCTCCTGGCCAT GGATGTGCATCTCGCTGTGCACAGCAGGGAAAGGTGTTCATGGAGGTACCTGCCTAGGCGTGGAACTTTGGGTTGCAGGATGTGTGAATGTTGAGCT TTACAAGATTATGCCAAACTGTTTTCCAAAGAGGTTGTGCCCATCTGTGCTGTCATCTTTGAGATTGTTTTTCCCATGGCCCAAGGCCCTTCTTCCC GCCCGAGGCAAGCCCACTCCTGAGGACTCCACTGCCTTGGGCCTTCACCGTCTTTCTCTCAGGATCCCATTCCCTACTGGAAAACTCTTTCCTTTCC CTCCTCCACTTGGCCCTGAACTTCCCAGGATTTTTCAAAACCCAGCTTGGAGCTGCCGTCTTCCTGGGAGTCCTCTCAGCCTCACTTCCACTCTCTC CCAGGTTTTTGGAACAGCTTTTCCAGACAGCTCTTGGGCCAGAGTAGGACATCGCATAGTGTGTTTCTTATTACATCAGCCCCACATAATCCTGTTG AGAAAGGCTTCTGGAGTCAAATAAACTTAAGAATCGCCACAGGCAACTTGGAGCCTCTTGGTGTTTATTGTTCTCATTTGAATATTAGCAGCTCATT AGCATAGTTGCAGCACTGAGAGGTCCTGCCAGTGTGACCCGTTTTTATTTGTTTAACTTGTTTTCCAAAAATATTTAACCTTGGAGCCCTTTTCCCA TTTTCCCCCATTTGGAAAATGGGATCGAGAAGATTCTCCTGCCTATTTCAGTCAGTTTGGTTTTGTGGTCTTATTTTCCTCGGTAACCAAGCTGAGA GTCCTCTGACTTCTGTTGTAATCATCCCGTGTAAACTAGTTCAGTCCAGACCACCCTTTCTGGAGGGCTTGAGTGGAAGGAATTAATGAATGCACTC AGGAATTAATGAATGAAGCAGTCAGCCAATCAGTCAGCCATCCAGCTGAGCCCCCTCTCCTATGCAGCAGCCAGGAACCAGGGACTGATCAGGCACC GCTCATCTTGCACCAGGGGACACCCGGGCTGTCTGGCTGGTGAATCATTGTCCCGTCTTAGGTCCCCTGTAGTTGCATTTTTAGGATCTGTCACCCA ATGAGGCTGGGAGCCCCTGCGGGGCAGGAACCAAGTTGCGCTTGCCTCTCTGTGTGCCCCGAGTGGGACATACAGATGGGATCTCTCATCCAACTCC TTCTGAGAGGGGCAGGAGAACATTGTGGTTAAGTCTTCAGCCTCTGGAGCCAGACCAGATGTGTCCCTAATTACCTGGGTAATGTGGGCCAATCTCT GCCTCAGTTTCCCCACTGAGATAGGGGTGATGATAACATACCTTCCTTACAGAATTATTATGGGGTTAATATGCGGCAAGCACACAAACAGTGCCTG ATCTACATCATTTCAATTCTTCCTCCCCGCAGCCTCTTTGAAGTGGGGGATGTTTTTCTCATTAGGAAGTTGAGTCCTCCCAAGGAGACGTGGTAAT GGGTGGTAGCAATAAGATCAGGATTGGGGTCAGCCAGATCACAAAGCCCTGGCCTGCAGGCGTGGAGGGTGCCACCTACCACCTGCGGATGGGACAG CTCCTCTGTTTCTTTTTACTGATAATTACCCTGCCGACAACCTGATCAGTTCTTTTTTTTTTAATCCTCTATTCATCTCAACAAAATGGAAATCCAT GGTACTGCAAGGGTTAGAATTTAACATGTGTGCACACGTGTGTGTGCGTGCATGCATGTGTGTGTGTGTGAGAGAGAGAGGGAGAGACAGAGACAGA GGTACTGCAAGGGTTAGAATTTAACATGTGTGCACACGTGTGTGTGCGTGCATGCATGTGTGTGTGTGTGAGAGAGAGAGGGAGAGACAGAGACAGA GAGAGACAGAGAGCAAGAGTGCACAAGTGAAGGAGAAGGAGTTAATCTGAGAAGCTGGGGGTTACTAGCACCTTCATGACAGACCAAGGAAGACAGA GATCCCCGGGTGGGGCTGGCTTTGAGACTGCACACGGCAGAATCGCTTGTGAGTCAGCAGTGCCGCAGAACAGCAGGGTGCTCCCGGAACTGGGCTT GGTGTCGTCACCCACTGCCCCTTGCACAGGGCCCTGTGTGCCGGGAAATGTTTGCAGGCTGGACACCTGTGGTTGCTTTTAACCAGGCAAGTGAGCT GGGTTAGAGGTAGCCACATGTTCCTGAGGGCTCGCAGCTTTGGATCTGAGAGGGTTAGACAGGGCGTCAGGGGCTGAGGGTCACTGGAGGAGAATTT GCTGTCGTCCCTTTGCCCACGGGCCGGCTGGTCTTCTCAGACCCCCAGAGGCCAGCTCCTCTGTTCTTCCCACCTCGGAGGGGAGCCCCAGAAGTCA CAGGGTCAGCTGTCTGCTTTCCACACTGCCTAGGGCTTTATTCTTGCACCATCCCCAGTTCTGGCCACACCAGGGGAGTGAGACATGGGGCGCCGGT AGAGGGGCTGAATGCGCTGGTGTGGGGTAGGAGGTTTCGGATGCACATTCCAGAGGGTGTTTATGGGGGAGCAGACAAGCCTGGGGATTCATTCCTG GTAGGGAACAATTCCCTCAGCACCCGAGGGTGGGAAATGAGGGCCAAAATGGTGGGCTCAGAGGGACACAGGTGAGGTAAGCAGGTAAGAATTCCAC CAGGTGTCTCAGAAATGTCCTGGGAAGGGCCTGGCATGGTGGCTCACACCTGTAATCCCAGTATTTTGGGAGGCCGAGGCGGGCAGATCACCTGTGG TCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTTCTAAAAATACAAAAATTAGCCAAGCATGGTGGTGGGTGCCTTTAATTCC AGCTACTCGGAAGGCTGAGGCACGAGAATCACTTGAACCTGGGAGGTGCAGGTTGCAGTGAGCTGGAATCGTACCTCTGCACTCCAGCCTGAGTGAC AGAGCAAGAATCTGTTAAAAAAAAAAAAAAAAAGAAAAAGAAAGAAAGAAAGAAAAGAAAGTCCTGGGAAGCTGGTGGAAGGAGGTCGAGATCTTAC CTGACCTGGGAAAGGAGGGAATTCCCAGGCATCTATAGACCAATAGGACTGTCGAAAGTTTGACTGGTGTGAGAATGGGTTAAGGTGCTGAATTTTA GATTTTTATCCTCTCCACGGTGGTACAGTGTGTTCTGCAAACAAAGGAGAGCCAGCCTTGAAGAGCCCTTCTCAGAGCTGACTATGTTCTTTGGCTC CTCAGCCCAGTGAGATGGCCTTAGCTCTGAGCCCTGTGCAATATGCAAACTGGACCAGATGACCCCCAAGGGTCCTTCTAGCTCTGACAGGTCCTGT CGGGGGATCCAGCCTGCATATAGGGCCTGGGCTTCTTTCAGCCCCATAGATGGTGACCCCTCTTCACCGCTAGTAAGATTGAAGCTCATCAGCAGGA CCTCAGGCCCTGGCCTCCTTTCTTCTTGGTCCCTTGGGTTTTGGAGTTTTATGTGACATCAATGTCCCAGAAATGCCCATCCTCTTCCTTTTCTCTC AGGGCACAGTCCCCTGAGGTCTTGTGGTTTATCCACCCCCACCCCTGTTCTATGTCCTCCTTCACTTGCTCTCCCCCACGCCCCTCCCACCAGAGAG TTTATAAGCTGGCTGTCCCCTTGCTAACCTCCTGCTGTTCCCTATGAACATGCCTGTTAGATTTCACCGTGTGACACTGTCTTGGTTATGTCCCCGT CGTGCCTAGTTCAGTGAAGAACACATAGCAGGTGCCGAATAAATGCACTCTGCTGGGATAAACTGGTTATCTCCAGAGGGTGGGGTCTGGACAGAGT GGCAAAATAGCTATAGCATGGGATTTGGGGTCCAACTCCACCTCCACTTCCTGGCCGATGGCAATCTGTCATTGGTAAACTGGAGCCGGCATCTCTA CTCTCAGGGCTGTTGAGAGGATTCATGGAGAAGCTGTGTGAGGAAATGCTTTGCAGGTTGGAAGGTGCTGGGAACGTGTGTCATCTACCCTGGCCTC TCTCTCAGGAACTCTTGCCCACATTTATCAGCATCTGCTGGGTGTGTTGTCTTGGGAGAGGTCTTGTTAACCCTCTGCCACCTTGAATTCTCTGGTC CCCTGAAATTCTTTGTCCTGTCTCACACACAAATGCCTCCAGCCCTCAGGTCGGGGGTCTCCTCTCCTCCTGCAATGCCTTGGGCGTGGGTCCAGCC TTGTCTGAGACACAGAGAAATGGACCTCCAGTGCGGAAGATCTGCACCAACATTCGAAAGAAAAAAGACTGATAGGCGGGAGCCCAGCATTTGAATT TTCAGGGATGTTAACCCCAACAGCGGCCGGAGCAGCAGAGCAGGACCTGAGCACTTCCTTCCCTTTCTCCTTAGCCTTCCATGAACATGCTCTCTAT AAACCCTGTCCTGGTAAATGTCTCCCCTCATTTTTTTTTTTTTTTTTTTTTTTTTTTTAGACAGGGTCTCACTCTGTTGCCCAGGCTAGAGTAAAAT GGCTCGATCTTGGCTCACTGCAGCCTTGACCTCCTGGGCTCAAGCAATCCTCCCAACTCAGCCTCTCAAGTAGCTGGGACTACAGGTGGTCACCACC ATGCCCAGCTAATTTTTTTTTTTTTTTAATTTTAGTAGAAACAAGGTCTTGCTTTCTCGGCTAGGCTAGTCTTGAACACCTGAGCTCAAGTGCTCCT CCCGCCTCGGCCTTTCAAAGTGCCGGGTTTACAGGTGTGAGCCACCTCCCTCAGCCCTCACTGCTTTTTTTGCCATCTCAGTGCCACCATTTCCTAG CTATGTGACTTTAGACGAGTCACTTGGCCTCTCTGAGCCCATGTCATCATCCGTTAAATTGGGTTCTTTGGCAAATTAAAGGATGTATTCTATGTAA AGTGCTTTACATGGCAACTGGCACATAGTCAGGCCTCAATAAATGTTAACTATTATTATTAATAATGGCCACTGGCCAGGCGTGATGGCTCACACCT GTAGTCCCAGCGCTTTGGGAGGCAGAGGTGGGCAGATCACGTGGTCAGTAGTTCGAGGCTAGCCTGGTCAACATAGTGAAACTCTGTCTCTACTAAA AATACAAAAATTAGCCAGGTGTGGTGGCATGCACCTATAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGT TGCAGTAAACCAACACGGCACCATTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAATAATAAAATGGCCACTCTGAGTGCCTCA GTTAATAGGCTCCTTACTACCTTACTTAGAGCAGAGTTGAGGAAATTGGTGAAGTTCTTCACTACCTTATTAGCCACTCTCTACCCAAATAAATGTA CCCCACCTTATCTTATTCATTATGGGTAATCACCTGTAAAAGCGTTCTTTATTTGATTCACAGCCTGAGTGTCCCCAAAAAGGTGCTCCATGACGTC ATCCCCCCTCTGGAGGACACCTCCTCCCACCCATGGTGATTTGAGCCTTCTCTTAGGCCAGGGTGATTCCTGGGGGAACCTTAACTGGGGCTAATGT GCACTGACATTTTGCCTTTTGTGTCGAACACACATCCCATTTGCAGAGATTTAGAATTTTTTGACTTTAAATGTTCGCTATTTCTATGTATGTGTAA GAGAGAGTTGTTTTCTTTTGTTTTGTTAAGAGACAGGATCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCAATCACAGCTTACTACAGCCTCA AACTCCTGGGCTCAAGCGATCCTCCTGCCTCAGTCTCCCCAGTAGCTGGGACTACAAGTGTGCACCACCACACCCAGCTAATTTTTCTGTGTTTTGT ACTAGACAGCGTCTCGGTGTGTTGCCCAGGCTGATCTCAAATTCCTGGCCTCAGGTGATCCCCCTGCCTCGAAATTCTGAAGGCTGTGATTATAGGC ATGCGCCACCATGCCAGAGAGAGAGATTTTATCTTTTCTACACAACGTGTGTTTCCCCCAGAAGAAATGCCTTCCTACTTCTTTGATGAATGTAAGT AGAATGCAGACAGAAATTACAGAAACTCCCTGTGCCCCAGCACCCTTACCAGGGCATGCCTGGCCTGGTGGAGTGACAGGGTGTTGTACACAGTGAG GGGAAGGAAGGGAGTGGGAGAGGAGGTGAGGCTCTGCAGAGCAGAGTGGACCATTTCTGGTCAGAAAACAGTGAGGAGGCCGGGCGTGGTGGCTCAC GTCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGTTGAAACCCCGTCTCT ACTAAAAATACAAAAAAATTTAGCCAGGTATGGTGGTCCTCGTCTGTAATCCCAGTTACTCAGGAGGAGAATCGCTTGAACCTGGAAGACGGAGGTT GCAGTGAGCTGAGATCACGCCACTGCACTACAGCCTGGGTGACAGGGCGAGACTCTGTCTCAGAAAAAAAAAAAAGAGTAAGGAAAGCGAAGTCCTG GGTTGGGGGGAAATGTAGCTGCAGGCAAGAACCAAGGAAGGTGTGGAGCCCCCAACCCAGTAGGGAAAAGGCTTGCTGCCTTGAACCCAAAGAGTGT GAGCATCCTGTACCTTTGCAGACAGAACTTCCACCTACTCACAAACAGATACACCCCACTGCACAGCTAAGAAAGCTAAGGGGAAACCAGGAAGAAG GGAAAAGAAAAGAGGAAAACCCCAGAGGAAACGAGGAGTCAGGCCTGGGCAGGGGGTTCCAGATGACGCATGAGTCTGCAGGAGGAAAAGGTTTCTT TGCCAAGGTGGACGGAAACGGAGGGGCGTGCCCAAATGCTTCTTCTTCATGGCTGCTGGATCAGGGAAGTTTTGCTTCTGTGGCCGTGAACATGGAG ATTTGCTGAGAGGCCAAGGAGAGAGATGATGGGGGAGGGCTACTTCGGGAGAGGAAGTGGACAAGACCAGAGGTTGGAAAACAGGGGACGGGTTGAT CCTAACAACTTGGAGGGACTGGTACTGGGAATAGGAGGTGGGGCCCAGGGGGAGGGCAGAGGACCCAGGAGCCCCAGCTGTGGACCCAGGGTGGGGC TGTGGGCAGGTCCCCAGCCCTGTCTGTGACCTAGGGCAGTGCTTCTCAACCTTGAGGGAGGGAGGGAGGATACCACAGAGGGGAGGGAGCACCTAGA CCACTTAAATCCCTTTCTCTGCAGGGGGCCCAGGCAGCCTTGTTTCTAAGCTCAGCAGGGCCACTTACTATGCAGCCAGGGATGAGAACCAATGGCC CACCCTGCTGAGTGCTGGAATGTGTAATGAAGTCCTGCGTGGGTCTGTAATGAACCCAGATTCGGCTCCTAACAGGTGCTGAGTGCATGTTTGCAAA CCCAGGCGCCTGTTGCAAGGAGAGGACAGAGCTAAAGCAAGGAGCCTGCGGAGGAATGGGTGGCAGGGACTGATGAAGTTGGGGGAAGGAGGTGCAG AGGAAAATGTTGAGGCTCGCTCTGGACTGCCTCGCCTGGGGATGGAGAATGGGGCTGCAAGGGAGGGGCAGCCAGCGCTTTGAACTTGGGTGGGGCC TCCCTAAATAGAGTGGGGGAAGTCCAGGTGCTGGGCAGGGCTGTCTTCACCTGCCCATCCTCAGCGCCGTGGGGGGATGAGGCGCAAAGAAGCCCTC CTGGGAATGTGGTGGAAATACCCACCTTGAAAGGTAGAGAGTGGAATCGTTGCCCTGAGCACCTGGGTGTGGTCGCAGCATCCCCCGTGAGGCCTCC CAACCTGCAGCTGCCTCCTGCGTGCGCATCTGCCACTGCGGCTTTAGGGCCAGGGCCAGGCCCAGCTGGAGGTCCAAGCTGGAGCCCTGGGGCAGTG TCCAGTGCACTGTGGCCTCAAAGTGCCCAGCCATGGTTTAGTACTCCAGCTGGCAAGGCCCTGGGTTCAAACCCTGCTCTGAATTTGTCCAGTTGCT TCCCCATGGTGTCATTTGGTTTGTTCCTCTGTCCCTTGTGTTCCCTGATAACAAGAGGTTACCTCTCAAAGCTTGGTTAGATCAGATTAAACGTCTT TGGCCAAAGAACATCATAGGGAAGGTTGGGGCCTTCCTGCTGCATCATCTCATACATTCTACTGTCACACTTCTGGTGGAGGCTTTTTAATGATCCA GTTTCCTGGACTCCTCTCCAGAGGCTCTGATCCTGCCACGCTGGTGTTGGAGCCTGGGTGTCTGTATTTTTCAAAACCACCCCAAGTGATCTGCCGT AGTGTATAGCCTGCATCCCTGACCCCAGTAGCCAGCTGGTCAGGGACTGTCCTTGGTTTTCTGAAGAGCATAGAATAAGAGAGTGGATGGGACAGTC CAGGTAGGTGCCAGCCCTGGTGGCCAGTGCTATCAGGTGTGAGGCAGGGAGGGTGGCCTCTGGGCCCCCATAAAGAGGAGAATGGGCTTCCTCAGGG CAGCTCCAGGTTCAGGTAAGAGTCCTTGCAAGACCAGGAGTGCCCCACGCACTGTGCTCCCGGCGTCCAGCATAAGGCCTGGCCCAGCGTGAATGTT TATTGAATAAAGACACACACCAGGCTGGTGGCTCTCTGAGGAGCCCTGGGGAGCTGCTCTAAGAGTGAGCTCCCAGCCAAGCAGCACAGCTTTGTGT GTTCCCCACTGGGCTGCTTCTAAGATTCAAACAAAGGACTCCCAAACTGTGGAGCTAGCAGCTGTGTTAAAAGGCCCCAGAGAGCCAGCAGGCCATG GCCATCACCTGCCCTCAGCTCGCCGTGGAGACAGCCTGTGGGACCTGGGAGAGACGAAGGAAAGGACTGGGCACTCAGTGGGGCTGCTGAGGGCAGT GAAAGGAGGCAGGGAGGTCCTCGCAGGGAGGTCCTCGCAGGGCCACTGCACCTGCTGAAGCAGGTGCTAGATTCTACATGGAAACGAGTGAAAGAAT CCCTCCTCTCAAAAAACTCACCATCAATGGAGTCGGTGGACAATTCACTTGAGTGCATTGAAGGTTACCTGTGACGGATGTATAAGAGCTGGGGAAA TGGCCAGAGGGAACAATTTGAATTGGAGACATTAAAAGGGGATTTAAACATGGGACCTTGAGGGATGAATAGAAGTCTGGAGTCAGAAGCGAACAAG AGGGCTGGGCAGGCTATGTCTTGTCTTTTACCAGAACTGGCTTGAAGGGTATAGCAATGTGGGGACCCAGCAAAATCCTGGTGTGGGAACCAGCAGA CTTGGCTGCTCAGAACGGACAGCCTAACTCTGTAAGGTTCTCATTTCCCAATCTGTAAAATGGGAGACTGACTTAGGGTTGGAGGGGTCAGGAAGGG GAGAAATGTTACAAGGTTAAAATGAATCTAAAGATGCAAACATGGCTTAGGAAAAATTTGAATTAGAATTCCACTTAGTGGAGTGGGAGCAAAGAAA CAGATGGCCAAGCTCCAGGAGGAAAAGCTGGCCAAGCTGAGCTCAACTTCAAGGCCCAGCTCGAATGTCACCTCTTTGAAGGGGACTTCTTTGCCTT CTCCCACTTCCTTCCCCTCAGCAGACCTATTCCTTGAAGTCCCAAGTGGGACTTCTCACACTCTGCAACTGACTGGTCACCTGCACTGAGGTGGGGT CACTGAGGAGGGTGGAGGCTACATCTTTTTTTTTTTTTTTTTTCTGAGGCAGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCG GCTCACTGAAACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTGTCTCAGCCTCCAGGGTAGCTGTGATTACAGGTGCCCACCACCACGCCTGGTTAA TTTTTTCTGTTTTTAGTAGAGACAGGCGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGACTTCAGTTGATCTGCCTGCCTTGGCCTCCCAA AGTGCCGGGAATACAGGCGTGAGCCACCGCGCCCGGCCGAGGCTACATCTCATACATCTTGGGCACATAGTATGCAGGTACTGAATGAGGCCCAGCC TTCAGATGATCAGGTCTGGGGCACTTCAAGAACGATCTGCGTGCTATGAGAGAGACAAGCTCTGGCTGGGAGTCAGCAGGCCTGGGCTGTGCTCTCT GCACTGCCTCCAACCAGTGGAGGAACAGCAGGGAAGGCACATCGCTTCCCTGGGCCTTAATTTCCCCAAGGAGCTGAACTAGGTGATGTCAAAGGTC CCGCTTAGCTTTGACATTTTATGACCTAACACTGTAATAGAATCACTAACATGCGTGGCCATTTACAGAATGCTCCTAAAGCCCTTCCAGGACACTC CTATTGTTCCCCCGCCCCCGCCCTACTCCAATAGCAAGAAAACTTTCACAGGTGGAGACTTTTCTTCAACAGGTCTTTATTGGCTGGGCACGCTGGC TCACACCTGTAATCCCAGCACTTGGGGAGGCTGAGGTGGGAGGATTGCTTGGGCCCAGGAGTTCGAAACCCAGCCTAGGCAATATAGCAGGACTTCA TCTCTACAAAAAATTTTAAAAACTTAGCAGAGCATAGTGGCATGTGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGTGGAAGGACTGGTTGAGCCA AGTAGTTCAAGGTCTGCAGTAAGCTGTGATTGTGCCACTGCACTGCAGCCTGTGTGACAGAGTGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAG AAAAGAAAAATGGCCTTTACTGAACATCTATCTTTGTACTGATGAGCACCCCCAGAGACACCTGGGCCCACCAGGGTTTCTAGAATGTTCTAGAATG TTCAGCATCCCCTGAGTTGCCAAGACTAGACATTTAGGGGGAGCTGTATGACAATCACCCAAAACTGATGGGCAGAAATGCTGTGACCCCAAGTAGG CCTCTGGGCCTTGATGACATCCTCAGTAACAGAGAGCACGGCACCCCTTTGTGTGTCTGAAGGCAGAGGGCTGGGACCCTACCTGAGCACGCACAGG GCATCTGGGCTTTACCTGGGAGTCCTGAACTGCGCAGCAAAGTGGAGAAACGGACCCAGCTCTCAGCATGTGTCCTTGGGAGCTGCTCCCCTCTGTG GTCACCAGGCAGCACTTGCCCACCTGTGGGCTTGGTGCCTCTCAGGGAGACGCTCTGGGGTCTGAAGAGTGAGGTCCCTGCCTTTTACCCGTCTCTG GACACCCCTCTGGGCCTAGGCCCTTCCCTGTGAATCCCCTGCCTGAAGGAAGAGACCCACAGCCCTGGGGTTCCTCTGGGGTGCCAAGTGGGGGACT GTGTTTGGTCCTGGGGAGGATGGGCTGGGGCTGCTGAGCAGGCCAGGGGTGCAGGACCCCTCCATCCCCCGCTTCTCCTGTCCTCCTCCTTCTTCCA CCCTTGACTCCTCTCACCTCTTGTCCCCTCTTCCCTCCTGTTTCCACTCTCTTTCCTCCTCCCCAGGTCCCACCAGACTGCTCCATGCCCCGGACCA CAATTTGGCTGAAGGCTACAATCCCTCTCTCGCACCCTCCTCCCTTTTTCCAGGCTTATCAACTTCACTTTCCTGTGAAATGAAGGGGTGGGGGGGT GGGTAAGAAAGAAGGAAAAAGCACTTCATGCTCACAACACAACAAAAAACAGGTTTAAACATTTTACAGGTTTCAACATTTTTCAGGCGGTCTTGTC ACATCTTATCAGATCAGCCAGAGCCGCAGGCAGGCGCTCCAGGAGCTGCTTTGGAGAACAGAAGCTGCAACATTCCAGCCCAGGCACTGCCCCGCCC TCCACACCCCTTCCCTCCCTTCCCTTTTCTCCCCAAAGAAACATCCCACAGGGCTCCCTGGGATGGAGCACAGGGCCCGCAGCCTCTTCCCTCTGAC TGAGGTATAGTCTGTGGCCAAACCCTTGGCTTTGAGCTTCTGCCCGCACCCTTTCCTTCTCCCCACGGCTGCCCAGAACCATGGTCCTCCCGGGCTC TCAGGTGGTCCCTGGCAGCTGAGCTGTGCCACCTCCTCGGAAGGCCCCTCGTGGCCCTGAAAGGGAACCTTCAGAAGCTGCGGGCAGAAGGGAGTTG CTAAGTCGTCCACAGCATGTAGAAGTGGTTCATTTGGCCAGCAGGGCTAGTGAGTTTCCGGGGCTCCTGGGGCCTGTCCTCGGTGGCTCCTGTCGGA GGGGAAGGAATAGCTTTTTCCTTGGTTATCTTTTCTCCGTGTGCATGGGTTTTTCTCCTATGGCGTGGATCACTGCCTGGGATATCCCCTTCCACTC AGTCACCCCCAGACCTCACCTTTCTGTTCCTGCTGCACTCACGGTGACATTAGTGACACAATGCAGGGTGACAGGTCCAGGAAGGGCTGGCCAAAGC CCAAAGGCTCAGAGTTAAGCCGAGGCAACGTGAGGGACAGACCCAGAACCTGGATCCCAGGACAACAGGGAAGAGCTGGCTTTGTAGCTTGTAACAG GAGCATGGTTAGGGCTGGGAGGTCCCACTGTGTGGTCAGAGAGGGGTCCCCAAGGGAAGGCAGCTGTGCACTGAAGGCTTAGGATGCATCATAAGAA AAGCAAAAAGGGGAGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGGGGGCAGATCACGAGGTCAGGAGATCGAGAC CATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAAATACAAAAAAATTAGCCGGGCATGGTGGCGGGTGCCTGTAGTCCAGGCTACTCGGGA GGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGTGGAGCTTGCAGTGACCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTC CATCTCAAAAAAAAAAAAAAGAAAAGCAAAAAGGGGAAAGCGCAGAGGAGGTAGGGGCACAGTGGCTCCCTCTGTGTAGGTATGTTGGCTGTGCATC TCGTGGGGACCTCGTCCGGAATATGGAAAACACAAGCCAGACCTGGGCGCCTGCTGCCAGTGTTGGCTGGGCAGGGGCTGAGGTTTCGGGAGACCCC ACCTTTCCAGCCTCCTAGTGTGAGGTTCAGGCCCTGAAGCTGGGCTGGCTGCCCCTTGGCCCCCAGCCCCCTCCCTGGTGCCTCCACCCCTTGGCAT ATGGCATCAATGCTCCCACCGTGACGCTCAGTGTCCTCCCACCGTGTGCCCACAGCCAAGATGGGGCCTAAAGTATAATTCAACTTTTAGCTCCTTA CAAGCATCCCCAGATGGATTTCTAGCTTCCGTCCCTCTCTTGGGCCCAGCTCTGTCTCTACGTGGTGCCTGGAAGTCCCTGTGGCCCCACGCACTTC CTCGTCTTGTTCCCAAAGCTGCTTTGCTTCTTACCTTCCCATCTTGGTGGACACCATCTCCATCTTCCTGGTCATCCTGGCTCAAAACTTTGGCCAT ACTTTCCTCCTTCCTCCTGTTTCTCATGGGACCAAACGGCTACCAGTCCTTATTCACAGCTTCCTGTCTGTTCCTGAAGCCACTGTCCTGAGATGAC CAGCGGGCCCATCCCCTGCCACAGACCCCGGTGACCCAGACACATGGGTCTTGGCCCAGCTGCACAATGAGAGCTGAGCCCTGGGAGGTTGCAATGG ATCCCCAGGCCCCAGAGTCTCCTTAGCATCCACGTCAACCCCGCCTCCCAGCCGCTTTCCCAGGACCCACCTCTTGTCTCATTTTGCACATAACTAA CAGGATGATATTCCAAGCCCAGCTAAAGGAAGGTGCTAGTTTGTCCGAATAATGTCTGGCACTCAGGGCCCCTTTCTAGCTGCTTCCCCTCCTCTGC TTCTCTGTGTGGCTCCTAGACCCTGGCTTGGGGAGGCATGCCACCTTGCCTGGGGCTGTCCCCCTGCCACCTGGCTCCACCTGAGGGCCCCTAGCCA TCCTTCTCCAGCTCGGTAGCTGCTCCACATGGAGCCCTCCAGAGGCAGTGAGGACACACTTGCCCCCGTTCCTAGAGATCGCTCGCCCTGACCATGC ACCCTCTGGCCCAGAGGTTTACTGGGGCTGAAGTTACAAGTGCCTTGGGACCATGTCTCACTCATTTAAGGCACCCACAGTGCCCAGACCTAGTAGG TGCTCAAGAAATGCTTGTTGGTCTGTTACTGACAGCAGCCTCCTGGGCTGGGTGCTCCTCAGGTGTGGCTTCATTAATCTCCACGTTCCCAGAACCT GGAACCCTGCCAGGCTGAGAGTCATCACTCAATTCGTGCGTGTTGAGTGAATAGGCAGTGAATGACGTTGTTTACCAAGGCCAGACTTTAACCTGCT CTCTGAAGGACAGGCACTTCCACTGACTCCACAAATCACCAGGCCCCAGTCTTGACAGCTGGGGCTAAATCAAGACAGGAGCCCACTGGGCTTAGAG CCCGGGCAGCTGCTCCTTCATGGTTTTATCTCAAGACCTTGGGTCCCAGCTCAGGGCCTGCACCCACTCTACCCTCACCCTTCCCTTCCTGTCCTAG ACATATGCAAGGGTGCTCCCACCCCTGCTGGAGATGCAGGCGAGCCAGAGGGCCCCGTTGAGAGAATGAACTAGCCCCGTTGAGAGAATGAACTAGC CCCTAATGGCAAGGCCCAGAGACATGTCCCACTTCTTTGATGAAAGGCACCCCCTGAGGCACCTTGGCGCTCTCCCACAGCCACAGGACACAGCCCC ACCTGAGTCCCTTTGGGCTCAGAAGAAACCCCCTACCCTTGGCCCTGCACTGAAATGTCAAGAAGGTCCAGACCTGTGCTCAGTACCCGCAGGGTGC ACATGTGTTCCAGGAGGGCGAGGAACAGTGGCAGCTGGAATCCTGAGCTAGGTTTCTCTGGTTTTGTCACAAGCTCCCTGCCAAGCAGCCAGGTGAG CGGCTCCAGTCCAGGCCTGTGGCCTCCCTCATCCACAGCAGTGATTGCCTCGTCACTATGGGTGTAGTTGGGTGCATCAGAGCCCACCAGGCCCAGC CCCACCGGTGTGCACACATGCCCCTGAACTGGCTAGGCTTCCTGTCCTGACATCTGCCAATCCTGAACGGTTCTTGACCTAAGTGGAAAGGTAGAGG CTGGGCCCAGGAACAAGTTGGGCCTCTGTCCAGTACTGCCCAGGAGCCAGCAGGTGGAGCACCTGGCCCTGGCCTGTTGTGGGGTTGACAGGAGCAC CGTGGCCCCCACCACAGGGAGAGGAAAAATGACCACAGGAGAGGTGATTTCTGACTCCTTCTCCTCACCTTCCCTCCTCCTCTCCTCTCAGCAGCCA TGTCAGTCATTTTAAGAGACACTAGATCTTCAGATCAGAGTCTTAAGATGCCTTCCCTTTGAGGCTGGCACAGATGGTTAGATTTCCGCATGGAGAA AGGTAAGGGCAAAGGGCCTATTTCTGCAAAGAAGGCATGACTTGGGGAGACTTGGCCCTGGAGAGAGCACCCTGAGACCGGAGGGAGGAGGGAGCTT TCCCTGGGCCGCAGCCCCTGGGTCCACCTTCTGCAGCCCCACCCATGTGAAGCCAGGTGGGTCCTTTTTGTGCCCAGCCCCAGAGAAGCTTCTGAGA ATGTGTGCATTCATCACCCCCAGGTTAAAGCCTGGTGGGTAAAAGAACTGTGAGCCCTGGTTCTCCTCCCACCTCCTGGGCAGCCAGCTGTGTGACC CCGGAAAATGACAAACCTCTCTGGGCCTCAATCCTTCCCGTATAGAGGAAGAGGGAATTAGACTAGACCCGGGCTCTGGAATTTCGTCCTGCACAGG GGCTCTAGGTGCAAAGTTGAAGGCTGGGGATGCAAGCACCATCCCTCCTTTGATTTTTTAATTTTGCATATTTAACCATTTTAAAGTGTACTATTCA GTGGCATTAAGTACATTCCAATGCTGTGCGACCATCACCACCGTCTGTTTTCATCATCCCAAACTCTGTACTTATTAAGCAGTAACTTCCCACTCCC ATGTGTCTGGCTGCTGTCGCTTAGCTTCTTTTCAAGTTTCTTCTATGTTGTAGCTTGCATCAGAATTTCATTCCTTTTTTTTTTTTTGAGACAGAGT CTTACTCTGTTGCCTAAGCTGGCGTGTCTTTACCTAGAACTTCATGTAAGTGAAATCATACAGTATTTGTTCTTCCGTGTCTGGCTTCTGTCGCTTA GCTTGTTTTCAAGTTTCCTCTACGTTGTAGCTTGCATCAGAAGCATCAGAATTTCATTCCTTCCTTTTTTTTGGTTGGGGGGACAGAGTCTTGCTCT GTCGCCCAAGCTGGAGTGCAGTGGCGCAACTGGCTCACTGTAACCTCTGCCTCTCAGGTTCAAGCAATACTCCTGTCTCAGCCTCCTGAGTAGCTGG GACTACAGGCACGCACCACCAGGCCCGGCTAATTTTTGTATTTTTGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCT GAGGTGATCCACCCGCCTCAGCCTCCCAAAATGCTGGCATTACCGCCACCACACCCGCTTCCTTCCTTTTTCTGGCTGAATAGGGTCCCACTGTATG TATGGGCCACCTGTTGTTTATCCATTCATCTGCTGAGGACTCTTGGGTTGTCTCTACCTTTTGGCTGCTGTGAGTAGCACTGCCGTGAAGACTGGTG TACAGGTGTCTGTTGGAGTCCCCATTTTCTTTCCTTTTTTTTTGAAACAGAGTCTTGCTCTGTCACCCAGGCTGGAGCGCAGT3GCGCCATCTCAGC TCACTGCAAGCTCTGCCTCCCAGGTTCATGCCATTCTCCTGCCTCAGCCTCTCTGAGTAGCTGGGGCTACAGGCGCCTGCCACCACGCCCGGCTAAT TTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAA GCGTGAGCCACCGCACCTGGGCGGAGTCCCCATTTTCAATTCTTTTGGCGTATACCAGGTGTGGCATTGCTGGATTATAGGGGTGATTCTATGTTTA ACTTTTTGAGGGACAGGGCCCTCTTTTCATATGTTCTGTATGTAGGGGAGAGGAGGGAGATTGTGTGTGATTCCATTTGGGAGGCCACCTGGTTGGG TGCAGGACTGCCTACCCTAATGGATCACTCAGGGGAGTGGGTGCTGGCAGCACAGTGGGTGTCCCTGGCAGCACAGTCAGACCCCCATCAGCAGGGG ATTGGCCGTCACTGGGTGGACGGCAGCATCTGAGGCCAACAACCCCAGTGTCAGATCAGGCAGGACGCACTGTACAGGGTGCCTTTAGGTGTCTCAC CATATGTTAGGTGCGTAAGTCAATGCAGCATCCAGGCTGACCTGAATTCACTGATTAAAAATGTTCTCTTAAAATGTTCTCTATGGGCAGGCATGGT GGCTTACGCCTGTTATCCCAGCACTTTGGGAGGCAGAGGTAGGTGGATCACTTGGTCGGGAGTTCCAGACCAGCCTGGCCAATATTGCGAAACCCTG TCTCTACTGAAAATACAAAAATTAGCTGGGCATGGTGACGCATGCCTCTTATCCCAGCTACTTGAGAGGCCGAGGCAGGAGAATCACTTGAACTCGG GAGGCAGAGGTTGCAGTGAGCCAAGATCACGCTTTGTACTCCAGCCCGGGCAACAGAGCAAGATTCTGTCTCAAAAAAAGAAAAAAAAGGTCCTCTC TGCCTTGTGCTCACCATGCAGGCCTCCTGCAGCCCTCTGGCCACAGCAGGCGTTATCAGGGTAGAGGCACAGAACTGGGGTGGGGATGGGAGTTAGA TAAGGCCATGCACAAGGTTTAGGTCTTGCCTATTTGTGGAGGGATATTTCACTCCAAGGGGTCAACACCAAAGTTTCCACAAGCAGCCCGTTGTGCA GGGCACCCGCAGCCCATCCGCCTGGCTGCCCGTGTGTGTCCTTGGCCCAGCTGGGCAGTGGGTGGTCGGAGTGGAGGATGAGCCGGCTTCAGGAGGA GGGTGGCAGGGTCCTAGGGAAGGGAAGGGCCGGGCCAGGAGCTGGGTATAAATAGCCCCTGGCCCAGCTGCGAAGGCCTGGCAGGGTCCTCCGCCCT CAAGGAGTCTTGTCCTGTGTGTAGGCGGAAGCTCCGGATGCCGGGAGGTCTGGCGAGTGAGGGGCATCAGGCTCGTCCTTTGGAAGAGTTCTTCATT CCTTTCCTCCAGAATCATGAATACCTAGCATGTGCCCGGCCCTTTGGAAGACCGAGTGGGCTGGGGTGTGTGTGTTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTGTGTGTGTGATGGGGTAGGGACCGGGGAATAACTGGAGAAAACACTACCACTACCTCTCTTCTTGGAGACTGAGACTGGCATAGCCAG ATGGAATTGGAAACAAATCAGTTCAGCACTTTGGGATAAGAAGGTTTGAATTAGGTACAGGAAAGATTCAGGCGGAGGAGAGGTGACTTCTGTCTGG AGCTCACAGAAGGCTTTAGAATGGTGGTGACCTAGGAATCAGGTTTCGAAGGATGGTGTAGAATGGTTGCCGGGGGCCGGGCAGTGGAGAGGTGCTT CGAGCCGAGGGCTCAGCATGTGCAAATGTGCAGAAGTGTGAAACAGCCCCGCTGGAGTCATTCAGCTGGCTAGGCAAATCCGTCAAAGCCACGCACA CTTTGGCACAAAGAATCGAGGAGCATGAGAGTCACTGTGCCGCGTCCCGAAGTGGAACGTGTACTTCAATAATGGGGAATAGGAGTGGCGAGTTAAA GTAATGTGTCTGCGATGGTGGAATTTCAGCAGTGTGCGGGCAGGAGGCTCAGGGTGGGGGTGGCCGGGCATGTTTGGGGAAGGGCAGCCATCCTGCA GAAATCAATCCCATGGCCACAGCCTCTTTAGTCTCCGACACTGGCCCAGGAGCTAAGCCCCATCGCCAGAGGCCTTGCTAATTACTCGCAGGATGAC CCCATCTGAACTGAAGCCTTTGAATGGAGCATCCTGAAAATGTCCTTTTGCCTGCACTCTTTGAGTGACCTTGAACCCTCATCCAGATCACAACTGT CTTTGTTCTGCCACCCCTGTGAGGACTGAGGTCTWTTCCAGGCATCCTTTCCAGTGTTGGATAGGAAGGGGCTGAGATTTCTGATGTGTTCTACCAA GTCAGGGATGCAAGGATGGGAGAAATGAGGTTGGTGACAAGGCAGGGAACAAAGTGCTGGGGACAGCTCCACACACACCGTAACCATAGCAACCACC ATCTAGCAAGGGCTCCCCACGTGCCATGCACTGGATTGTGTCACTTATTCCTCCTGTCGTGTCTATTTTACCGATMTAGAAACTGAGGTATAGAGGT TAAGAAAATTGCTGAGATCAGCAGCTAGGAAGTGGTAGAGCTGGATGGGACCCTGGCACCATGGCTCCCAGGTCCACAGTTGGTGGGACCTGGGCAA CAGGAAGGAGACAGGGTTTGGTGGAAAGAGGGAAAACAGCTCATCATGACTGAGGCTCAGGAATTGTTCTCAGAGGACATCACACTGGGATTCAGAC AAACTCAGGGCTTGAATTCTGGCTCAGCCACTTCCTTGCATAAGTCGCCCAACTACTCCATGCCTCAGTTTCCTCATCTGCAAAATGGGGATAACAA TGCCCACCTCCCAGAGTTGTTGTGAGGATTCAGTGAGATTATGTATTTGAAGTGACTGGCACAGAGCAAGTGCTACATAAATAGTTGTCATTAGTAT TGCCAGTATCCGGGTACTGTGGGGACAGAAGGAAATCCCTGTGGGGCAGAGGAGAGACTGCGTCTGCACAGCAGGAAGGGGCTCAGTGGCACCTTCT TCCTGGAGATGTCTGGGAAGCACTCCGACCTTTGAGGCCAATCAAGCCATGCAGGCAGTGTGCCAGAGCTCAGGTGCTCTGCTGGGCTGCGAAGACC CACCTGGGACCCTGAGGGAGGTAACTGGTGAAACCAGGAAGCAGGGAGCCCCTTGGAGAGCTGGGTGAGGAGCCGCCTTGCCAGCATGGGCCCCCCG ACTCCTCAGTCCCCCAAGCCAGCCGGCCTGGCTTTCTCTGTGGATATGGCTGTGTGACCTCGCACAAGTTGGTCCTCTTTCACGGCCTCTGCTTTTT CTTTTTCCTTTTTTGTTTTGAGACGAAGTCTCGCTCTGTCGCCCAAGCTGGAGTGCAGCGGCATGATCTTGGCTCACAACAACCTCCACCTCCCAGG TTCAAGCGATTCTCCTGCCTCAGCCTTCTGGGTAGCTCGGATTACAGGCGTGAGCCACCTGGCATGGTCGGCCTCTGTTTTTCATCTGTATAATGGG CTTTGTGCTCCCTTAGGGCTCCTCCTGTGGGTTCTGCTGCTGGACCAGGGCTCAGCCTCCAGTTTAGCTTGAGGGTGCCCAGGCCTGCAGAAGGTGT CAAGCAAGGGCTGGGAGAGGGGGAGGAAGGAGGAGGCAGGAAGGCAACGGGAGGGGAAGGAGGAGGGCAGAGGAAGGGTCTCCGAGTGCCTCTCACT CCCGCCTCAGCTCTCCGCTCCAGTGGTCCCATATAGGGCTCTGGGTCCCAAACACCAGAGGAAGGAGCGGGGACAGCCCAGGCTTCTTCCCTGGGTC TTGTTCCTGAGCTGCCCATCTAGGATGGTGCAAGGCCGAGTTGTCTGCACTGAACTCTCCCTCAGTTTCCCCTCCAGTGATTGCAGGGCTGTGGGGG CAGCTGGCACAGCAGGGCTGGGCTGGAGATGCTGCTTAAGAGCACGGGAGGGGCAGCCTGAGCCCAGAGGGAGGCTCAACGGGGACCTTTGCAGCCT GGCAGACAGGGCAGGGTACTTAGCTCCCTGGCCTCAGTTTCCTTATCTTGGAAATGGGACAATGGCGATGATAATGAAGTTTTTATTACAGACCTGC CGTGAGGATTACATAAGGTAACAGACACAAGCACTCAGAACTGTGTCCAGCACATGATAGGCCCATAATAAACCACAGGGATTATATGATCACTCTA ACCTGCTTCTAACAGGGCAGGGGCAGTGCTGTGTGCGCCGTGTGCCCATCAGGGCTCTGGGCTCACTGACTCTACCCACTTGGCATGTGGCTCAGTA TGGAGGCCCAGGGTGCAGATGGGCCAGGCCTGAAGCCACCTTCACCCCATGAAGACCCAGGCAGGCACTGCCCAGCAGGCAGGGTCACATAGTGATG ACCCCCATGGGCTCTGGAGTCTGACACCCTGGGTTCCAACCAGCAATTCCATAGGAGCTCTGTGGTCTGGGGTGCTTCATCAACCTGCAAGGCTAAG CCATCTGTAAAATGGGGCTAATAATGACCCTACTTTGTGCTGGGGCTATTTTGAGGATTAAATGAGGCAAACCCAAGGAAAAGCCTCTGCTCAGGGC CAGGCACCGGGGAAATCTAGTAATTAGCCATTACCACCGATAAATCAGAACTTCTGGGCCGGGCGTGGTGGCTCGCGCCTGTAATCCCAGCACTTGG GAGGCCGAGGTGTGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCG GGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATC ACGTCACTGCATTCCAGCCTGGGTGACACAGCGAGACTCTGTCTAAAAAAAAAAAAAAAAAAAAAAAGAACTTCTGGCTGCTGCTTCTTTCTCTTTA GAAAAAGCTCAGTGCTTAAGACCTGGAATGCCTCACAGATGTTACCATCCAAACTCCCAGATCTGGCTCCTCAGTTCCTCCACCAAAATAAAACAAA TGGAAAAAGGAGAACCTGCCTCTCCCCCTGACAACTGAGCCTGGAGACAACCAAGGTGGATGGGTAGCATGCCCTGCACGGTGCCCAGGGGAGCTCT GTGCCTTGGAGTCTCCACGAATTGGCCAAGGCCAACATCAAGCTCAAGTATGGAGGAGGGACCCGGGGGAAGGCACATGGCACTCTCTGACCCACCA CAGACCAAAAAAGCCGTAGGCAAGCTAATTCACTCTCTAAACCTCAGTTTCCTAGTCCAGGAGATAGTGATGTTCTTCATGTTTGGAATTGATCAGA AATGTTGTATATAAAGTGCCTGGCAAGCAGTAACAGTTGCCAAATGGCAGATGTTTGGCTCGGCCCTGTGTCCAGCCCAGAAGCTTTTGTGTACTAA AAAGCACACAAAAAACCTCACCCTGCCCCATGGGGTCTTCTCCCGGCCCCTCTTTCCGAGGCTTTTGCCATCACTTTTTTGTGGGAAACTTGACTTA GGCCAATGCTGGACCAAAGCCTTGGTCAGTGCTGGACACAGAGGGAGAGGAGATGGGCCCCTTCTTCCAGCTCACACTGCCCCTGGTCATAGAGCAG ATTGCAATTGTCCTTGAAGGCCACTGACACTCACGGATCATTTTCTCAGGTTCTCCCAGAAAATGTCATTTCTGCTGTTCCTGTGCTGAGGGCAGGG AACGGAAAAGTCGTAATTCCTACCTTGGTTTTCTAGTATTTTAAACTCTTCTGCCCCACCCCCATAAGGTCATTCTTTCTGTTGTTGACTATAAAAC CTGAGAGAGTTGATGGGATATTGATTACAAAGCGAGGGGCAGAGGAATGGAGTGAATTGACCAGTCACCTGGTGTTGGGTGTGGGCAGTGAGATCTG AGATCTCCCTTCTGACTCTGTGCTAAACTTGTTTTGACACAAAGCCAAGCTCCAGTCTCTCATGAGAAAAGAGGTGGAGCTCTAGAAACTTCTAGGA AACTGGAAAAGATGGTCATGGAGGCCCTGGTAGACAAAGGACTTGGTGCAAGCCAGCAATTCCTTGGGGAGATACTGGGAGGCTCTGGGCTGGCTGG CACCATCGCAGGGAAGAGGCTGAGGGCATTGCCAAGGGTAGTGTGTGTGTGTGCGCGCGCGCGCGTGTCCCATGAGTCACTGGAAGTGTCCATGTGG CCCCAGTATCCTGGACTGCCTTGGAAATTGCCCAGCCTGATCTCTTCAATGCCCATCAGGGAAGCTGGACCCAGAACCTGGAAAGGACTGGATCTGG GCCCCAAATACCATCTTTCTAGTCCAAACCTCTTTTCATGGCTTTGCATTGCCCCCAAGGGCCCCCACAAGCGGCTTCTGCGGTCCCATCCCCCTGC AAGCTGGATGCAGCCAGAGGGCTGACTTGCGTGGGTCAGAGCTCTGCGCTTTGAGGGGCGGCATGCTCCCGAGGTCAAAGGTAGCACATTCAGGTGC CAGGGCACAGGCCCTCTGCCTCTCCACCTACCCCGGAGGGTTCACAAAGCGGCCATGGTGCCCAGGATGGGCTCTGTGCTTTGTGCCCACAGTGTTA CTACCCTCTGTCTGCCTGCAGGTCCCTGGCCCTGGGCCAGCAGTACACATCTCTGGGCTCACAGCCCCTGCTCTGCGGCTCCATCCCAGGCCTGGTC CCCAAGCAACTGCGCTTCTGCCGCAATTACATCGAGATCATGCCCAGCGTGGCCGAGGGCGTGAAGCTGGGCATCCAGGAGTGCCAGCACCAGTTCC GGGGCCGCCGCTGGAACTGCACCACCATAGATGACAGCCTGGCCATCTTTGGGCCCGTCCTCGACAAAGGTACTGCCTTGGGGCTGAGGGGGGGGGA GGGGCTGGGTGGGGGGAGGGATCAGGACTGTATGCCCTTCCACCCCAGTCAGGGTGCCTCTTCTCTGAAGCCAGGGTCCCTCTGGGAGGGTGATAAA TTTGGTTGCATGACTGCCACACCTTCCCAGGCGCTGCTGGGGGCTGGGCCGCCTTGAGATGCTGCAGGATCCTGAGGTTTGAGGGCCGACACCAAGA AGGCCACAGACTTCCTTCCTGGCTTTTGCACAGTGGGCGCCTCAGGCTCCTGCTGTGGACATTTGTGACATTTCCCCAATGCTGTGTTAAGTGCTAT GCAAATACCGCTTTGGGGTGGGGGTGAGAGCATTGCCACCCCTAGGTCCCTCCCATCTAGAAAGTCCTCAGTAGGTGAGGAAGCTGCCTGGTGCTGT GGTAGCATTGCGTTGCCCCCAAGAGCCCCCTCTGGGTTCTGTTCATCCTCATGCCCTGTCAGCTGGATATGCCCAGGAATCATGGTGGGGCTAGAGG GTGCACTGGCCTCTGGGTAACTTTCCGGCCGTCTTGCAGCCTGGGAGTCTAACTGGCTGTGCCTCAAGTGGACAGGGAACCACATGATTTGACTTTG AACCTGCAGGCCCTGGGAGGGAGGCTAAGTGGGACAACTCCTCCCAAGAAGGGGACTTGGGGGGCTCATGGATGGGTGGAAGATGGGCAGCTCTTTG TGGAACGGCAGTGTCCAGGAATTTAACGATCCTGGCCGGGGTGGCCACAGCCAGAGTTGCTCTGCCACCCAAACCGCTGAGCCTGGCCCTCCCTCCT ATTAGAAGCTAGGGAATGAATGAGAGCTGCCTATACAGCCAGAAAGAAAAGGGATCTGACGTTCAGGTGAAGGGGTGGGGTGCTGGGTGGGGTTGGG GGGGAAGCTGACAACCCCCATTTTAGAGTGCAGTTCCCCTTTAGCGGTGCCTCAGGTGCTCAGGGTCTGTCCCACCTACAGGCAAAGTGCTGGCTAT TGTCATGGGACAGGAGGGTAATTAGCAAATCAATGGATGATGATTCTGTTTACGCTTCTATTGCCAAAACTAATTATTCCTTGTTGACATAAAAGAT TTGGCCTCTTAATTGGGGCCAAGTGGCGGCGGTTTGCATTTCAAACTCGTTCTTGTCGGTGTGTTGGTCTCAGCGCTTTCCGGTGCCCCTCCTCGGG CCAGGTAGCGCTGAATCAAACAACCCTGCGTCTAGACGCGCTCCCCAAAAGCGAGTCACCTCTGATCGCTCTTCCCGTCTCCGGCCAAGAGCCAGGG GAAAGCGGCTCTGGGAGCGCTACCCATTCACTCCGCGTTGAACGTTTTAAGTCACCACCGTAGGTTCTGGCACACGCCCCGGTCCCTAGATGGCCCG AGGACAGGTTTGGGTTGCGGGGGGAGGGGCGATGTGTGCCCGAGAGTTTGGGAATTTGCTGGCGGCGGCGAGGAGAGCATCCCGGAAGACGCCGCGA GCGCATACGCGCCCCGGTCGGTGCCCAGAGCCCGGACCTTGAACCCAGGTTCGCGCCCAGGTCCGGCCCCACGTTTGCACCCCGCCCCCGGCGAGTC CCCACACCACCGCCGCGTGGGCGGCCAAGGGTTAATCTCTGCCCCGCGCTTTGAGACCCGGGGCGCAGCGGGTCGGGCAGCCCGGGGCGCGCGTCTT CCGCGAGTCTGGGGGCGGCGGGGTCGGCGGCCGGAAGGGGCGAGGCGCGGCGGCGGCGCGGCGGGCCCGAGGCGGTTCCCCAGGCGGGGGCGGGGGC AGGGGCGGGGGCGGGCGCCGGAGGGGCCTGGGCGGCCTGAAAAGCGCCCGAGCACCGCCCCCCCACCGCGCGGCCGCCGCGCCATTCACACGCCCTC TGGCCATTCGGCGCGGCGCGGCGCGGCGCGGGGGCGGGGGGCGCCGCTTCAATGGGGATTTCGCGGCCCGGCGCCGGGGCCGGGGGCGCGGCCCGGC CGCGGGAGCCGCCCGTTGCTACGCGGTGGCGGCCGGCCCGGCGGCCCGGGCCCGGCGGCCGCATTATGCGGGTAATGCGGTGTGACACCGCGCGAAC AAAGTCGGATTGACCGGCCCAGCGGGCCCCGCCGGACGGGGAAGGCACAGCGGGGCTGTCAGCGCCGCTCCCAGGCTAATCCCCGCCCCGCCCCCGC CGCCCCCGCGTTCCCGGGGCTGGGAACCCAGCGCGGCCCGGGGCCCGGGCGCCGCTGCCGCCGCGAGAGGCCGCAGGCCGGCCGGAAACGAGGGGCG CCCGCCCTGTGAACCCGCCCTCGGCCCCTCTTCCCCGAGGCGCCCCCAGGGCTGGGGCGTCTAGGATTGGGGCGAGTGAGCGGCGCGGCTGGGACCC CGAGGCCGGGAGCACAACTGGACGCGGGACGTCGGGCCCCCTTGCCGCCGTCCTCGGTCGGCCCTGGCAGCGCAGGCGCGGGGCGCGGGCGGGACCA GCTCTGCACTCTTCGCCCTCCCGTCGTTGGAAGTGGGACGGGCCCCTCTGTAGGTGGCTCAGGAGGGCGTGGGGGCCGCGGAGAGCGGCCGCGGGAG CCAAGAGGGGTCCCGGGCTTCCTTCTTGCAGCACTCGGCCAACAGCCCAGGAGGGGAGGCGGGCGCCTGGCTTCTAAATAAATTTGGTCACATTTAT GACCAATTTTGCCGACTAGGCCGGCCCGGCGTTTCACAGCCTGTGTCAGGTGGCGAGTCACCTCCGGCTCCCGGGTCCTGCCATGAGGAGAGAGATG GTTGGGCTGCAGGTCTTGCAGGCCTTGGCCTCCCTAATCGTCAATGTCCACATCTATAAAATGAGTAAAACTTTCCATGTGAATGAAGCACATGCAG AGACGATGACCGTTGTGAGGAGGCTGGAGCACACCCTTGAGAGTCTCTCCTTTCCCTGCGCTGGACCCTGGGACAGAACCAGGGGAACTGCCCGGTG TCCCTACCCTTCTGGGAGGGAGTTGGCCGTGCCTGGGCGTGAGGGCAGGAGAATGGGGATGGGGAGACTGAGGCACGGGCCACTGCCCTCCTGGTGA GGGGCTGTAGGAGCGGAGGGAAGCCGTGTCCATTTTACAAAAAGGGCGACTGAGACCGAGAAAAGGAGAGGGGCCGTCCCTATGCATCCACGTGCGG AAGGGGTGGGCCTGGGCAGGTTTAGGCTGTAGATTCCCAGGCCTCCCTCCTTACAGACCTGGATCTCACTCAGGCGTGGGAGGGCTCAGGCCTGTGC AGGGTGGTCTCTGGACTTTGGGAAGGTGGAGGGCAGGGGGTGTGGGACCAGGACAGAAGTGGCTGCCTTATTTCTGCAGCAACCTGCCAGAGCTTTG GTGTCGGCGCCTGTTTCTAACAGGCACTGCTTTGCCCTGTGGCATTTGAGGTCCTGAGCTAATCAGCAGCCCAGGGCCTCAGTTTGCTCATCGGTGA AGTGGGAATACCCAACTGGGTCTAAACCAGCCAAATAGGGTGGGGAAGCTGCCTCCCTCTTGCCTCAGGGCTGGTGAGCTCTTCAACTCTTCCTGGC CTCGTTCCCCTCACGTCCTGGCCTGGGAGGTGGAGGCAGGGCAGGCGCTCCCAGGCCGGGTCCTGAGTGCTGCCTCCCCACGACCTCCCCGCAGCCA CCCGCGAGTCGGCCTTCGTTCACGCCATCGCCTCGGCCGGCGTGGCCTTCGCCGTCACCCGCTCCTGCGCCGAGGGCACCTCCACCATTTGCGGCTG TGACTCGCATCATAAGGGGCCGCCTGGCGAAGGCTGGAAGTGGGGCGGCTGCAGCGAGGACGCTGACTTCGGCGTGTTAGTGTCCAGGGAGTTCGCG GATGCGCGCGAGAACAGGCCGGACGCGCGCTCGGCCATGAACAAGCACAACAACGAGGCGGGCCGCACGGTGAGCCCGGCTACCCTCCCCAAACCCT TCAGGGAGCAGCCCCCCGCTTCCCCTCCGGAGCTGCCCTGGCCCCCACCTCACCCCTTCCGGCAGCCCTGTGGGTCGCGGGCTCCTTTTCCCCTTGG CCAGGCTTGGCCTCCTCCCCACCCCACAGCCACTTCGTCTGTCCACCCTCCTTCCTCCTTGGGCAGTTCCTGGACTCCACCCCACCCGGGATGAGTC GGCCTGGGAGCATGGCCACCCCGTGGGATCAGGTGCCACCCACCACCCATCCTGTGCACCTTGGCACGCGGTGTAGGGCTGTCAAGTCCTGGGAACC TGGCTTTGAATTCAGCCTCCACTCCCTTACTATGCTTGTATGATCTAGGGTGAGTCACGTTAAGTTCCCAGCCTCAGTTTCCCCATGTGTTAAATGG AGATAACTCCTATTTCTTTTTTCTTTTTCTTTTCTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCAGTCGCCCAGGCTGGAGTGCAGTTCTGG ATCTTGGGTCCCTGCAACGTCCGCCTCCCGAGTTCAAGCAATTCTCCGGCCTCAACCTCCCAAGTAGCTGGGATTACAGGCGTCCGCCACCACACCA GCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACTTCAGGTGATCCTCCCGCCTCATCGTCC CAAGGTGCTGGGATTACCACCGCGCCTGGGCAACAACTCGTATTTCATGCGCTGTGAGAAGTGGACGTGCTGTCTACCCATGCTTGGGGTGTGAAGG GGGAGGGAAACATGGTCACTATTCTTTAGGTCTTGCCTCAGTCCCCATCAGTTCTCTTCCTGTCACAGAGGAGTAGAGAAGGCTGGAGGGAAGGGGG TGGGCAGTGGCAGAGAGGGAAGCCTGGATGTGCCCCCTCGTGGGGGGTCGGTCTGTTGGCCAGCTGCTCTTCTCTCCCCCAGACTATCCTGGACCAC ATGCACCTCAAATGCAAGTGCCACGGGCTGTCGGGCAGCTGTGAGGTGAAGACCTGCTGGTGGGCGCAGCCTGACTTCCGTGCCATCGGTGACTTCC TCAAGGACAAGTATGACAGCGCCTCGGAGATGGTAGTAGAGAAGCACCGTGAGTCCCGAGGCTGGGGTGGAGACCCTCCGGGCAAGTACTCGCTCTT CAAGCCACCCACGGAGAGGGACCTGGTCTACTACGAGAACTCCCCCAACTTTTGTGAGCCCAACCAGAGACGGGTTCCCTTTGGCACAAGGGACCGG ACTTGCAATGTCACCTCCCACGGCATCGATGGCTGCGATCTGCTCTGCTGTGGCCGGGGCCACAACACGAGGACGGAGAAGCGGAAGGAAAAATGCC ACTGCATCTTCCACTGGTGCTGCTACGTCAGGTGCCAGGAGTGTATTCGCATCTACGACGTGCACACCTGCAAGTAGGGCACCAGGTAGGGCTCCGG GAAGCAGGGGGGAGGCTGGGAGCCTGGGCGCAGGGAATGGGGTTGTTTGCCCATCTCGTCTTCTTGACGACCCCCTTCTGTTTCTAAGCTATCCAAG ACACACAAGTTCCCACAGCCAAAATAGGAAGCTAGGATTTTTCAAGCATCCGTGGGAATGGTCCTTGGGCAGAGACTTGGTGGATTGCACAAAGCAC AGATAAAAACCCAGTGTTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGACGGATCACCTGAGGTCAGGAGTT CGAGACCGGCCTGGCCAACATGGTGAAACCCGTCTCTACTAAAACTACAAAAAATTAGCCGGGCGTTGTGGCAGGTGCCTGTAATCCAGCTGCTTGG GAGGCTGAGGCAGGAGGATTGCTTGAACCTGGGCGACAGAGGTTGCAATGAACTGAGATTGCACCACTGGACTCCATCCAGCCTGGGCGACAGAGTG AGACTCCATCTCAAACAAACAAACAAACAACAAAAAAAAAACAAAATTCAGTGTGTGCACATTAGGTGCCAGCAATTGATTAACATTTTTACACAAG TTAGTTATGAGCCAGATCAATTTTTTGCATAGCTGCTAGCTGTCATTCTTGAGCATTATTTGGAGATGGGGGGCTGGAAGCTGGGAGACCTGACGTC TGGTCCTAACTTTGTCAGTAACTTCCTGTTCTTTCACTTTTCTGGGCCTCAGCTTTCTTACTATAAAGTGGTGATGGTGGTGAAGGGCAGGGGGCAG TTTAAATACCTCAAGCAGCGAGCCAAAATGTCTCCTCTACCCCTGAGGCAGAGTCAGTGTGCATCCACCTTGAACTTAGAGGGCAAGTTCCTGCACA AGCATAAATCGTACCAACCTCAGGGAGGTGGGTGGGGGGAAGCGGCATATAAGCCCATATCCTGACAGATCTGAAGCTTGGGTGGAGTGGGGAGCAC TCTCACCGAGTTTATGGATGATGACGGGGAGCAGGAGGGATTCAAGTTCAGAGTGGCTGGGATGAGTAATCGAGGGATCAAAGGCGGGTGGATTTTG TTCCCAAGCTTCCCAGAGGTGGCCTGCATGGGAGGCGCTATGCACTGGCCCTGGGTTCCACAGCACCCCGGGATAGGTCAGCATGGATGAGGAGTGG TCCTGGACCCCCGGGGTGGAAGGTTTTAAGGCTGGGGTGCCCTTTCTTCCTTTTCTGTCCCCTGAGAAGGAGCCTAGTGTGTCGAGGCATGAGCATG GGTGTTGGAATTAGGCCCTGCCCTGCTCCAGCTCCTACCACTTGCCAACCGTGTGACCCAAGCAAGAAATTCTTCATAGACCTGGTTCCTCATCTGT CATCCTCCCCAGAGATGCTGTGAGGGACAAATGAAAGGACACCGAGGACAGGGCTTGGTTAATTGGGAAGCACTTCCCTGGTGGGTCATTGTTGTCT GGGGTGCTGCTGGGCGAGAGCAGCCTGTGAAAGGGTAGAGTGCCCCCTCTTCCTGCAGTTCCACAGGGCACCTCTGAGCTACTGGCACATGTCTGTG CCATAGGGAGTAGGGGAGGGAAGTGGACGGGCCTCTCTGAGATATGGGAGGTACTTGACGTCATGGAGAAGAGCTCTGGCTGAGGGGCGACTCACTC AGCCCATCTAGGAAGCCCCTCGGTGTAGCTCAAGTTCTGTCCTGGTGGGGACAGTCCAGAAAGGCAGCAGGTGGCACTACCTTTGTCGGTATCTGAA CAAAAGCAGTGTGGGGAGTGGGAGAGGACGAAGGTGAATCCAGCGCCTCCACTCGTCCACTCAGCTGTCTGGCCTGGGAGCGCCAGTTTCCTCCTCT GTTCAGTGGTGGTGACAATGGGAGCCCAGCAGAACTTTTTTTTTTTTTTTGAGACTGAGTCTCTCTTTGTCGCCCAGGCTGGAGTGAAGTGCGCAAT CTCGGCTCACTGTAACCTCCGCCACCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTATAGGTGCCCGCCACCACGATCGG CTAATTTTTTTATTTTTAGTAGAGACGGGTTTCGCCATGCTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCCGTCTTGGCCCCTCA AAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAGAATCAGTACTCTTCATCAGCCCTCTTTCTCCCCATTTCTGAAATGGACAATGAGTG TTTTTTTTCCTCAATCTTATGTAAAGTGCTACATAGATATGGTTTCAAGATGGTGTGTCCAAGTGGTTCCTACCCGGAACCCCTTCTCTGTGGAAGC TCTGGAGGCCTCACTCTGTGACCAGTGGAGGACACTCTCCCAACATGGTGCCCTTCTGATAAACACTCCCAGGCCAGCTCTTCTGCCTCGCTGAGCC CTGGCTTCTTCATTTGTGAACTGGGGATGAGAACTGTGTTCTGTGTAGGGTTGTCCTGTGGACTGGAGACCCTGCACATGAAGGGCCTGGCCCAGGA CCCAGCTGCTCACAGGGCAGCCACAGAGGCTCCTGGGCCTAGCAGAGCTGACCTCCCAGAGCCACCTCCCCAGGCGAGAGCCGCCTGCTCTGGAGCA ATGGGCCCAGGCTCGGCCGAGACTCCGCTAGGCAAGACGGGAGCCTGCGGGATGCACTGGCAGGGATGGCAGGGGACAGAGTCGTTAGCTGTTCTCT TGTCTTCCCTTACAGTCTTGGCAGTGCAGGCAGGAGAGAGAAGGGAGTCGCAGAGCAGGCCCCGGGCCCTCCACACGGTGAGGAGAGAGCGCCTGTC AAATGGCTTGTGTCCTTCCTTTGTGGGGAAAACACCTTTTCTGTAGCTTTTTGTAGCTTTTACCCAGTGTCTCTGGCTAACCATTGATTTGGTGCCT TACAAGTGCCAGATTTATTCCTCGTCACTCTGCTGTTGTGAACATGGTGAGCTGGAGCTGGAAAGGTTCTGGCAAGAGTCGAGTGGCCTGGCTGCGC CCAAGTCCTGGATCTGTTACTGCCTTGCTGAGAGACCTTGGATGTGTCCCTTCAATCTGGCTGAGCCTGTTTCTGCCTCTGTAAAGTAGTCTTATCT TGGCCTTGTCAGCCCCCTAGAAGACCTGGGGGTTGACTGGGAATGCCTCAAACCCTTTGTGAGATATGACTATGCAAATGAGTAAAATGAACACACT GCTGCTCCAATGGGAAGGAATTGTTCGTTATTAAGTAGGCTCTCTCCCATTTGGACAGCTCATTATCAAGCTATTTGGTGCGGTACAAAAACACAGT GCATGCCTGGCGTGAGCCCAGCACAGCAGTTGACTTGGAGTTGGGGACTGGGCCCTCGGCCAGGCACCGTTTCTCCCATCCTGAGTGACCTGCTCCT GGGCTTCCTGTTGCCCAAGGCCCTCAGCTAGAGGTGGGGGAGGTAGAATTTCGATCCCATTCTGTGGACTCGAAAGCCTTACTGCTCCTGTGACTCA TACGACCTCCCTCAACAGCAGGCCCAAAGCACAGAGGAGAGCGTGGAGAAACCACCCAAGTCCTCATCACCTCTGAGCACCAGGGACACGTTCAGAT CCATCAGCAGCCTCTGATCTTTGAACCCCAATGGGTGGTCTCTGGGAATGGAATTATGTTTCTAATTCTTCCTCTTGATTTTCCCCAAGGGCGCTGG GAAGGGGTGAAGTGTGTGGCTGGGCGGATTCAGCGAAGTCTCATGGGAAGCAGGACCTAGAGCCGGGCACAGCCCTCAGCGTCAGACAGCAAGGAAC TGTCACCAGCCGCACGCGTGGTAAATGACCCAGACCCAACTCGCCTGTGGACGGGGAGGCTCTCCCTCTCTCTCATCTTACATTTCTCACCCTACTC TGGATGGTGTGTGGTTTTTAAAGAAGGGGGCTTTCTTTTTAGTTCTCTAGGGTCTGATAGGAACAGACCTGAGGCTTATCTTTGCACATGTTAAAGA AAATAAAAATGAAAAAAAATTTGACTCCAACAGAACAGGCTGGGCTAATGTGAGCTCTCAGCCTGGCAGTCAAGACATCAGCATGGGCAAGGTTCTG TTTCCAAACTGCTGCTTCTGGTGACATTCCAAGACGCCTGGAGGGTGGGAGTCAGGAAGTAGGACACACCCCTGCAGTCTCCTTTTCTTGGTCCACT CCCATTCAAATTTGAGCTAATTTCTCATTCTGATAAAAGCCATAGGTTTAGCTAGGATGAAGTGGTAGGAAGGTCCGTGGCAGTTGTTAGAGTAGGA TTTGGAGTTTGGAAGAACTGGCAGCTCAGGGTGGCCTGGTCAGCCGTTTGAAGAGCAGCCATGTGTTCTTCTCAGTCTCATTTTCTCTATAACCCTG TTCTGCACGAGGGGCAGTCAGATCTCAAAATCTTTTTCTACCATTCTGCAGTTTCCACCGTCAATGCAGTTTTTTTTTTGTTTTTTTGTTTTTTTTT TTTTTTTGGTGGTAGTGGACCTTGTAAATAGGCTATGTAAGGGGGCAAGTCTTCTCTAGCTCAAATGGCTTCCTAAATAAATAAGCGGTATCTTCAG AAGGGGCCATTCAGTCCTTCCCAGCCCTGCTCACCTGCAGATTCTCTGTACAAATAACTCCAGGTAGAGCAGTTGGACTCCAGGTCACCTTAGTATA AGTTAGACAAAGGGTCCGTGAGGGAGTAGCCATCAATTCCTGAAATTCCAACTTTGTGACTAGCAGATGGGGAGGATGAAAACCATCCCTTTGCTTC CTCTCCAATACGGACCCATCTTACTGTGTCCTTTCCTCTCTGGGGCCAATGTGAGTAAACACAGACACAGAGTTCTTTCCCCCAGCTCTTCCTCCCT CACCTGCATGCTGAGATAGCTTCCATCCATGCAGTTCCCAAGGATCTGGATTAGAAGTTCAAAGGGGAACCAGCAGTCACCTACTCCCTTAGGTGAA GCATCVCACGGCTGAGTTCTCCCTGAGGCATACTGGTCCAGCTGAGCGTCCTAGAGAAAGCTAGCAATAGGGAGGCACATGGATTTCACAGTATGAA TTGGTTCAACAACTGTCTTAGGGAGAATCAGAAAGAAGAGATGCAGCAGGGGAATGAGCAGAACAAAGATTTTTCTTTCTCCCCCTTCTCTCTGGGG TCTACCTAACCCTGACCTAAAATACCAGGGCAGCGATCTCCCAGCTGGTGCAGGTGGGCTTGCCAAGATGGTCGTCCAGGAGCCCGCCTTCACTTCT AAATCTGCTGGCCACAAGCCCTGCTAAAGATACACATCTCACCCCCTCCGCCAAGTCTGAAATGCCCCTCCCCATCTCACCTTAGACTGAAAAGTTT TAAATCATGTCAACTGGATAATACTTGCTTTATGTGAGAATACTTCAGCAGAATGGATACGAATTTTCAAAACAATCTTTTCATATCTATGTATTCT ATATTAAAAAGTGATAAAGTCATGTTTCTGGGGCGTATTCAAGTAGCTGACAAGTAATTATTAATAATAGTACATGAGTGCATTGTAATGATTCTCG CCGTAGTCAGGTAATAGTATCCAAGCGAAATTTCCTACCAACCTGCTGTATCCAAAGTTTTGTAAAAAGTTGTAGAAGTTGTTGATCTTTTTGATTT TATATTCAAAAAGTCTCTTTTTATAAATATTATTTATTATACAATGTATATACCTTTGAGTTAACTAAGATTATATATTATATAAATATATATATAT TTGGAGAAAAATATATTTCATCATGCAGTTTTTTTCTGTTAAGTCATTAAAGAGAAGGTAAACAACCTAAAATGGATACATTGTACACTGTGTGGAG TTTCCAGATTAATGCTCAGGAGGTCAAGGATACGAGATTCTGAACATGGTGGCCTCAGCTAATTAAATGACCAAGTGAAGGTTATTTCCTCTGTTTT CTAAGCAAGATCATCAGAGATGTCACGGACAGTGGGTCTGATACACGACAGTACATTTTTAAAGGCTTCTTTTGTTCTAAGTTAACTTCTAACAATG AATTTCCAGTTTTAGAAAACAACAACTTGTGTACTAATTCATTTCACAGACTCAAGTATTTTCAATGTATAAATTAATGTCACAGGCACTCCTAAAA GATGTGGCCCAAGGCCAGCAGACCGCAGGGGTGGCCACTGCCTTAATCCCCTCCTCACCACGTTTTCAACTCCATTTAATGGGAAAATAGGATTTTC TCTATTGAAAATGAAACTTGACTGAAAATTGTCTGTCCCCTGCTAGCTCCACTGTGAGAGCTAAGCCGTAGAGGGAGGTAGGCTGGTCTACAAGAAG AAAGCGTGTGCCCTGGGCTGTGGGCTGTCTGGAACAATTGTCATTTGAAGTTGGGTTTGGGTTTGGGTAGAAAGGGCCTGCCAGTGGGCATGCTCTG GGGATGGGCACCCTCTCAGATCGCCACTTCACAGGACCCACTGGAAGCTCACAGGTTATGCCTTCTCAACAATGAGATGCCACAAGTTGGTTTTATG ACAACAGACAATCCTTTAGTTTCAGACCTACCCATAAAATGTCACCTTTGGTTTATTCAGCACATTATTTCAGAGAATAACAAAAATGTTTTTTTCT TTTTATTTCTCCTGACCTACCTCATTTAGGAACAAATCTTACCTCACTACGAAGAGAAATAATGAGAACAGGCTGGGTGGGGTGGCTCAGACCTGTA ATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCTTAGGCCAACATGGTGAAAGCCCGTTTTACTAAAA ATACAAAAATTAGCAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTACTTGAGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAG GTGCAATGAGCTGAGATCGCACCACTGTACTCCAGCCTGGGTGACAAGGCGAGACTCCATCTCAAAAAAAAAAAAAAAACAAACAAAAAAAAACCAG GAAAATAAAGCCATGAGCCGCCTATGGTGGAGGCGGGCTGCTCTGCGCTGTATTCAGACCTGTGACCTGAGGTTAGGAATAGCCACCAGAAGTTGAT GCACTCTGTTTTGTCCATGATGTGTCTTTAGCCCCCTGAAAAGCTGAAACCACAAAAACTGTTACACTTCAGCCTACAACGAATCGGACACGTACAG GATACAGATCTCCTCTACATCTTACAGTCTGGTCATTTTTATTTCATTTCGACTTTTTATTTTTCTTTTTGCATAAAGCTAATGCAGGTGACTACAC CTTTTTCTGAAATGCTTGGGACCAGAAATATTTCAGACTTGGAAGATTTGCATATATACAATGAGGTATCTTGGGGATGGGACCCAAGTCTAAACAC GAAATTCATTGATTTCATATGCACCTTACACACATAGCCTGAAGGTAATTTTATGAATTTTTAAATAATTTTTGTGCATGAAACAGTTTAGACTGCA TTTTGAATTTTTGATTGCCACCTGTCACACAAGGTCAGGTGTGGAATTTCCACTTGTGGCATCCTGTCGGTGCTGAAAAGTTTTAGATTTTAGAGCA TTTCAGATTTTGGATTTTTAGATTAGGATGCTCGACTGAACTTATCTATCCCAGAATTCTAGGTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTGAGATAGGGTCTTCCTCTGTTGCCCAGGCTGGAGTACAGTGGTGTGATCATGGCTCACTGCAGCCTTGACCTCCTGGGCTCAAGTGACCTCCT ACCTCAGGCTCCCGTGTAGCTGGGACCATAGGCATGTGTCACCATGCCCAGCTAATTTTTTAATTTTTTTTTTTTAGAGATGAGGTCTTGCTATGTT GCTCAGGCTGGTCTTGAACTCCTAGCCTCAAATGATCTCCCACCTCAGCCTCTCAGCATTGGGACTACAGGCATGAGCCACCCTGCCTGGCCATTAC TTTTTCAATCAATAAGATTGCCAAATATTTAAATGGTCCCTATTCATACTAATGAAGACCATTTGTAATCGTATGATTAGTTTTTAATTTTTAAGAG ACAAGTGTCTATGTCACTCAGGAGTACAGTGGCATGATCATGGCTCAACACAGCCTTGACCCCCTGGGCTCAAATGATCCTCCTCAGCCTCCCAAGT AACTAGGACTCAGGCGCACTCTACTATGGTAATTAAAAATAAAATCTTTTGTAGAGATGGGGTCTTGCTGTGTTGCCCACTGGTCTCAAACTCCTGG GTTCAGGGGGTCCTCCCACTTCAGCCTCCCAAAGTGTTGGGATTACTGGGTGAGCCATCACACCCTGCCCAGTCTTMTTTGATGGTTAAGGAGAATA CAGTTGATAGCTGTGCTTGAACATGTAGTTTCTCCTTATGTATAAGTACTTACAAACGTCTAAACACAAGAGGACGTTGTTTAAAAATCTGAAAGAG ACGACATAATTAGAAGATATCTTTCAAAGCAATATTATTTTATGAAGAAAGAAGGGAAGGAAAGCATGTGAGACAGTTCAAGGATGAGGGGATGAGG TACAAAGAAAGGTTGGAAGGAAAGAAGGTAGGGAAAAAGAAAGCAAGGAAACATGATGGCGACATGATTCTTGGTGTTACCTAATGCCGTCTCCCCT GGTGGCCCTGGGCATAGGGACATGTTCTTGTGTGTGTGGCTGGTCTGCACACTCGAGTGAAGTCAGTGCAGCTACGCATTGCTGCTACACTGCCACT GTTTCTCCTAGTTTAATAGAGAACCTTCTAGGAGGCAAAAATTTCTTACCATTAATCTTATACTCCCAAAATAGTGAGACAGAAGTTGCATGGCGTC TACGCTGGGAAAATTTCAAACATGATCCCTGCTTGGATTTTTTGTCTTCACCCACTTGGGATGCTTGCCAATCACAGGCGCTATCTCCCGCATCTTT ATGCCATGGTGCCCGTCCAGCACACACCCTTGTGGGCTCGTCTCCAGGACCCAGTCTCAGTACGGCTTGCCAGCTGATGAGAAACTCTACATCATTT TGCAATAAATTCTGCAACTTACCTGCTTTCTTGAACTCTCATACACACCCTTCCCCAGTCACTTTTTTTATTTTTCGAGACAAGAGTTTTGCTCGTT GCCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCATCCTCCCAAGTAGCTGAG AGGTGATTGCCCGCCTCAGCCTCCCAAAGCTCTGGGATTACAAGTGTGAGCTACTGCGCCCGGCTGCCCCCAGTCACTTCTTTAAAGAGGCTATGGA CCAAGTTGTCAGGCAAGGAAAATGAAATCCTGCTTTCACCTTCTGTGTTTGGGCTGGGGTGTTTGTTTATAGCTGACTCACTGTTTCAACAAGTCTG TTGATCAGGATTTGATTATTGTACACACTTCAATCTACTCCATGATTTTGTGACTTGTTGCTGAAACTTTTAAAGGGGAGGCTGCAATTTTTAGGAT ATGAAAAGACAGCCTTAAAGTAAAAACATATTTCTGACTTTAACCACAAATATGCAATTTTTCTGTGTGACATTGAAAAAAAGTGTCCCAGTGAAGA TGTACAAATTTAGAAAGGATAAAATAACCTCCTCTTTTGAGGTTTTGATCTCAAAAACATCTTATGACAAAAAAATAGCCGGTTAACAATTCGCCTA TAGATGAAGAAACCTAAGGCAGCAGCTAGCTGGAGCCTCCTTTGCTTCTTCACAGGCCGTTCTGTAATCTCATACGCTCTGCTGTACAGCACTGGCT TTGAAGAATATTTGGGCAGCTTCAAGAACCCACCTTCTCAAGGCTATGCAGGGACCAGGTCGGCCTCAGGGTCCTCCTCCCAGGAACTCCCGTT Human Sequence—mRNA GCGCTTCTGACAAGCCCGAAAGTCATTTCCAATCTCAAGTGGACTTTGTTCCAACTATTGGGGGCGTCGCTCCCCCTCYTCATGGTCGCGGGCAAAC TTCCTCCTCGGCGCCTCTTCTAATGGAGCCCCACCTGCTCGGGCTGCTCCTCGGCCTCCTGCTCGGTGGCACCAGGGTCCTCGCTGGCTACCCAATT TGGTGGTCCCTGGCCCTGGGCCAGCAGTACACATCTCTGGGCTCACAGCCCCTGCTCTGCGGCTCCATCCCAGGCCTGGTCCCCAAGCAACTGCGCT TCTGCCGCAATTACATCGAGATCATGCCCAGCGTGGCCGAGGGCGTGAAGCTGGGCATCCAGGAGTGCCAGGACCAGTTCCGGGGCCGCCGCTGGAA CTGCACCACCATAGATGACAGCCTGGCCATCTTTGGGCCCGTCCTCGACAAAGCCACCCGCGAGTCGGCCTTCGTTCACGCCATCGCCTCGGCCGGC GTGGCCTTCGCCGTCACCCGCTCCTGCGCCGAGGGCACCTCCACCATTTGCGGCTGTGACTCGCATCATAAGGGGCCGCCTGGCGAAGGCTGGAAGT GGGGCGGCTGCAGCGAGGACGCTGACTTCGGCGTGTTAGTGTCCAGGGAGTTCGCGGATGCGCGCGAGAACAGGCCGGACGCGCGCTCGGCCATGAA CAAGCACAACAACGAGGCGGGCCGCACGACTATCCTGGACCACATGCACCTCAAATGCAAGTGCCACGGGCTGTCGGGCAGCTGTGAGGTGAAGACC TGCTGGTGGGCGCAGCCTGACTTCCGTGCCATCGGTGACTTCCTCAAGGACAAGTATGACAGCGCCTCGGAGATGGTAGTAGAGAAGCACCGTGAGT CCCGAGGCTGGGTGGAGACCCTCCGGGCCAAGTACTCGCTCTTCAAGCCACCCACGGAGAGGGACCTGGTCTACTACGAGAACTCCCCCAACTTTTG TGAGCCCAACCCAGAGACGGGTTCCTTTGGCACAAGGGACCGGACTTGCAATGTCACCTCCCACGGCATCGATGGCTGCGATCTGCTCTGCTGTGGC CGGGGCCACAACACGAGGACGGAGAAGCGGAAGGAAAAATGCCACTGCATCTTCCACTGGTGCTGCTACGTCAGCTGCCAGGAGTGTATTCCCATCT ACGACGTGCACACCTGCAAGTAGGGCACCAG Human Sequence—Coding ATGGAGCCCCACCTGCTCGGGCTGCTCCTCGGCCTCCTGCTCGGTGGCACCAGGGTCCTCGCTGGCTACCCAATTTGGTGGTCCCTGGCCCTGGGCC AGCAGTACACATCTCTGGGCTCACAGCCCCTGCTCTGCGGCTCCATCCCAGGCCTGGTCCCCAAGCAACTGCGCTTCTGCCGCAATTACATCGAGAT CATGCCCAGCGTGGCCGAGGGCGTGAAGCTGGGCATCCAGGAGTGCCAGCACCAGTTCCGGGGCCGCCGCTGGAACTGCACCACCATAGATGACAGC CTGGCCATCTTTGGGCCCGTCCTCGACAAAGCCACCCGCGAGTCGGCCTTCGTTCACGCCATCGCCTCGGCCGGCGTGGCCTTCGCCGTCACCCGCT TGACTTCGGCGTGTTAGTGTCCAGGGAGTTCGCGGATGCGCGCGAGAACAGGCCGGACGCGCGCTCGGCCATGAACAAGCACAACAACGAGGCGGGC CGCACGACTATCCTGGACCACATGCACCTCAAATGCAAGTGCCACGGGCTGTCGGGCAGCTGTGAGGTGAAGACCTGCTGGTGGGCGCAGCCTGACT TCCGTGCCATCGGTGACTTCCTCAAGGACAAGTATGACAGCGCCTCGGAGATGGTAGTAGAGAAGCACCGTGAGTCCCGAGGCTGGGTGGAGACCCT CCGGGCCAAGTACTCGCTCTTCAAGCCACCCACGGAGAGGGACCTGGTCTACTACGAGAACTCCCCCAACTTTTGTGAGCCCAACCCAGAGACGGGT TCCTTTGGCACAAGGGACCGGACTTGCAATGTCACCTCCCACGGCATCGATGGCTGCGATCTGCTCTGCTGTGGCCGGGGCCACAACACGAGGACGG AGAAGCGGAAGGAAAAATGCCACTGCATCTTCCACTGGTGCTGCTACGTCAGCTGCCAGGAGTGTATTCGCATCTACGACGTGCACACCTGCAAGTA G

[0299] TABLE VIII MOUSE NOMENCLATURE ICSGNM  Batf Celera  mCG5472 HUMAN NOMENCLATURE HGNC    BATF Celera  hCG22346 MOUSE SEQUENCE—GENOMIC CCCAGGCATGGTTTTAAGCGATTGGCTGGCATCACATGGTTACAGAGTGGCAAAGCCAGACACGAGCTTGCAAGGTCAAACTCACAGCTAAAAGACC ATTTGCCTGTTCTCTTGCTTCCTAGGCCTTTTCTCCCCACCCCAACCCCCATCCCTATCATCATCTTAGGATCCTGTGAAGGCCAGAGGCTGCAAAC CAATTTGCTTTACATTACACTCCCAAAGCACCTCACTCCTGGGAGGTCAGACACCTTTTGCAAGGCCCGGTGTAGACGGGATTCACCCTCCCTGCCA AGAATAAAGGGCTGGGTGTGTCCCATGATTGCCTGGTTGTAGCACAAACATAGCTTTAGACATGCTGCTTCACTGTTAATCCATTTTCTTTTTATTA TTGTAGCCTCTTTCACTTTTCTCTGTGGTCTGCACATGGATGTGAGCTCACTCACGTAGGCATGGGGGCCAGAAGTCAACAGAGCTGTCTTCTTTTA TTCCTCTCAACGTTATTTTTAAAATATATAATAGTTGTTCTTTGAGAATTTCATGCATACATACGATGAGTTTTGGTCATATTGGCTCCTCAGTCTT CCTCGCAATTCCTTCTAGATCCACCCCTCACCTTCCTACACCCTTACACCTTGGTGCCTCCTCCTTCTTTTAATAACTCATAAAGTTCAATTTGTGC TGCCCAAATACACACAATCACTAGAACAAGGTCAACCTACCAGATGCTCCAAGAAAGCTGAGTTTCCTTTTCCTCTGACACTTTTTGTCCCCTTTCC TGCAACAGTCCTGAGTCTTGGAGGGTGTATGTGATGTAGGTGCCATTTGTACTGAACACTCCACAGCACTTGTTCTCTGTACACTGACCAGTTCACA AGTGTTTGCATTAACCACCATCCGCTGTACAAAGAAACATCTCTGATGAGGGCCAAGAGCTTCATTAATCTATGGATACAAGGATGCAAACTGAAAG AACTGTCCATTTATCAAATAATAGTAGTAGGCTCACTTCTGGAGCCTGTGAGTGCCTCCACCATGGGCTTTGCCCAGACTTACAGTACCAGGCAAGA GTTTTATTCTTTGGAGGAAGTCTTAAATCTATTCTGAAAGTAGTTGGGTTAACTCCATAATGGTTGTGCCACTAATACTTAGGTATATTGTGCCATG TTGGGCATTACTGTGGCTACCAGAATACACAGCTGGGTAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGAGTGCTCTTAACTGCTGAGCCATCTCTGTGGGCCCACTCCCACGTTT TGGTTTTGGTTTTTTGAGACAGGTATCTCTTTGTGTTGTGCTGGTTGTCTTGGAACTCTATAGATCAGGCTGGCCTCGAACTCACAGCGATCCACCT TCCTCTGCATCCTGAGTGCTGGCATTAAAGGCATTTGCCACCACTGCCTGCAAGTCCTTCACTTTTTTTTTTATCTGATGGAAGACTAAAATTTAGT ACCTCTCTCTTGCCTTTTGAGGGGCCTGGGTCCATGCCTTCTGGTCTGAAAGGTAAAAGCAGATTGGAAGCTTCCAGAAGCAACTGAGTGCCTCAGG AGCTCTGCTGTCAGGTTGAAGACTCTAAAGCGGCTCGGAGCAAGGACGTCATTGGCCTGGCTTTATCTCAAGGAGGAGGAGACAGAGGAGGCCACAG GCTGAGACTGACGGATGGAGCAGAAGTTTAGGATCTAGGAGCTTCCTCCCTCAGAGCATCTGGTGATGACCAGAGATGTGTCAGATCTTCTCACCTG GGGTTCTACTGAAGTCTGGTGAGTGGAGGACCAGGGCCTGGCCTGCTAGGCCAGAGACAGCCCCCACAACAAAGACTCCTGTGGCCAGAAGATCACA AAAACTGCCCTTTTCCTTTTCTGCTAGCCTCACGAAGAGCCAGCTAATGATGGTTTCCTGCAGTCTTCATCTAGGCTGAAAAGGCAGGGGACCAGGC TACCGGCCACTGCAAGGGACTTTCCTCACCATCACCTGGCCATCCCCTCTGGCCCCTTCCGTGGAGAGCTCTGCCCTCAGGTAAATGTTTTCTCAAC TTGTTTGGGGAACTTCGTAAAAACTCCCCGCTAGCCATCTCATAAGCTGTGAAGGTGTGCCTTAATGTGCTTTTTTCCACTAAAAAGGTTTGTTTAA AAAAAAAAAAACTAGAGCAGCCAGGGGATTTTTATTATTTTTTTTGTTCAAATAACTAAATAGCAGCCCATATGAAGACTTCAAAGTTAACACATCT CAAGAGTATCCCTCAAAAGGGAGCTCAGAAAAAAAAAGCGGCAGAGTGGGGGGTTTAAATGTCGTGAATCAACTCATGGCTTAGACAGGAAAAGTTG GTAACCTGGGCGGTCTGGTCTGCCTCAGGAAACAGCCAGACAAGGTTGGGCATCAGTGCATGGGAGCATGGAAGGAGCCTTAAACTTCTCCCGTAGC CGGGAACCAGCAGCCTAGCCTCTGGGGAGCCGGGGTCATTTGCATGCGCTCTTAAGAGACTCTTGCTTATAATTCCCTAGTGTCATCTTTAGTAACT AAAGGGGTTTCTAGGGAATGGGAGGCCAGTGCCCCGGGTATATGAACTAGCCTAGCCACCTGGTTCAGAAGCACCAGTGAGAGCCAAGTGGGAGTGT AGGAGGCCTTGGTGCCTGGAAGTTGCTAGATAACTTGAGGCAGATGGTGAGAATGGATCACTGTCTACTTGAGACCTTTTAGGCAGAAGAGTTTGAG GCTGTGGGTGCTGATGGGACCCAGTGAGTCAACTCTTGCATATCCCCAGAGAGTCAAAAGATAACAGAGGCCAGTTGGATCTCCTCCTCTTGCTGAG ACACTAAGCTGGCCCCTGAGGTCACACACTGTCCCCTACTGGACAATGTGTCCAGAACTTCGCATCCAACAAAGGGCCTGATGAGTGACCAGCATTA GGGGTCAAGCCAGCATTTCCTTCCTTCTCCCTGGCTTTGGGAAATGTCCCACCGCCTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNGCACCTTCTCCACAGTCAGCCCAGGCCCACACCCACACTATGTTGTCCTGGGTTTCTTATGTGACTGGAGCCTCCCTGACC TTGTCAATCACCAGGTAGAGGGAGCCCAAAGCCTGTGAACTGAGTTGATAGTTGGATGTTGCAGTGGAGCCTGTCTTTATGGAAACAGGGAAGAGCA AAGATAGGGCACCTGGGCTGACATGAATATACACTGTTACACTTAAAAAGCAAAACCAAAGAGACCCTGTTTCGGATGACCTTAAGAAACCCCTGTG CAGGGCTTGGAAAGAGGGCTCAGCAGTAAAGAGCACTCCTTGTTCCTGGTGAGCTCCCGGCATCCATATGATAGCTTACAACTGTCTGTAAATCCAG TTTCGGGGGATCCAATGCCCTTTTGTGACTTCTGCAGGCATCAGGCATGCGTGTAGTGCACGTACACACGTGTAGGCAAAATAGCCGTACACATGAA AAAATAAATCTAAAAATATTTTTAAAAGACAGAAACCATTTGCGTATGGTATATTCTGCTGATCTGAAACAAGGTTGATGACTAGGCATTCCAATGC CTGCTATGGAAAGACTGAAATACGGGTTGTCAGTTTGACCTTAGCCCTTAGAGTTTCTTCCATTTTGTTCCTACCTTATCCATTCTCCTGAAAATCA GCAACCAAATCACTACTGCCATGGCTCAGAGGAGCTGGAGTCTGCTCCGACCACTGAGGGCTCACCATGGGACAAATGGACAGACAAGTAGTGGTCC CTGATTGTACATCATCTCTGTTGCTCATGACAACAGCTGCGTGGGGCTCTCTGCTTATCATATTCAGCTGGATCCCTGCACATCGGCTTTTAATTTC ACAAGTCTTCATCATGTCCTCCACGTAGCAGAAAATGCTCTAGAGGATTGTACACTATAACTCGTTTGAGTCTTGGAATAGCCTAGAGGAATTTGGG ACTTTCCCTTTTGATAATTAGCCAGATGTGGTGGAGAGGTGGGCCTCCAGTGTGGGCTAGCTCCATCATAGAAAGTATCACCAGGAGGGTCTGGCGT TATGGCTCAGCTGGAATAAAGGTGCTTGCCACAAAGGCTGAGGACTTCAGGTGATCCACGTGGTAGAACGAGAGAATTAACTCCTCCCAAGCTGTCT CCTGTGACCTCCACACCCACAGGGCACACATCACCTACACATACACACACTCATATATACATTAAGACACCATGACCAAATGTAACTCTGGGGGGAA AGGGTTTGTTTGTTTCCTTTTACAGGTTGTAGTTCTTTAACCAGGGAGGTCAGGGCAGGAACTTAAGACAGGAGCCTGGAGGCAGGAGCTGAAGGAG ATGCCATGGAGGGGGTGTTGCTTACTGGCTTGCTCTCCATGGCTTACTCAGCTTGCTTTCTTATAGAACCCCAGGGTGGGACCACCGACAGTAATCT GGACCCTCCCACGTCAATTATCAGAGGAGAAGATGTACCCCAGGCTCGCCCACAGGCTAATCTGGTGGGAACTTTTTTTTTTCAGTTGAGGTTCCCT CTTCCCAAATTACTCTATCTGATGTCAAGCTGACATAAAAGCAGCCAGCACAGTCAGGGTTATAAAGTCAGCAGAGGGGACAGCCAGGAGAAAACAC GCTACTGCCTTTGACTCCCCCTTTAGCTGCATCTGATGGAATTCCCCCAGACATTAATTTGGGGAGTATGGTGGGCTTAAGAAATGTCCTCAAGTAT TGTGTGTGTGTGGGGGGGGGGGGAGGTGTTTCTCACTATGTAGTCTTGACTGGCCTGAAGCTAGCTATGTAGACCAGTCTGGCCTTGAACTCATGAA GATCTGGCTGCTTCTCTACCCCCACCTCCACCCCCAAGTACTGAGATGACAAGCACGTGCCACCACAACCAGCCAGTCTTCAAATTCTTTAATATTC CTACCTTAAATAGGTGGGGGTCTTAGCCTGTGGTGGTATACCCCTTTAAGATCAGCACTTGCAGCTGGGCGGTGGTGGCGCACGCCTTTAATCCUTG CACTTGGCAGAGGCAGGCGGATTTCTAAGTTCAAGGCCAGCCTGGACTACAAAGTGAGTTCCAGGAAAGCCAGGGCTGTACAGAGAAACCCTGTCTT GGGAAAAAAAAAAAAAAAAGACCAGCACTTGGGAGGCAGAGGCAGGTAAATCTCTGTGGGTTCAAGGCCAAACTGGTCTTCATAGTGAGTCTGTCTC AAAACAATAACAGAGTTTGGAGAGATGGCTCAGAAGTTTGGTTCCCAACATTGATGTGGTGGCTCACAGTCATCTGTAACGCCAGTCCCAGAGAATC TGGCGCCCCTCTTCTGGCCTTGTGGGTATTGCACACACATGGAACACAGACACACATGCAAACAGAAACATCCTACACATGAAAATTAATTAATTAA TTAATTAATTAATTTTTAAAAAGATTGAAAGCAATAACAAAAGAGGTGAAGTCTCTTTAGTCTCCCCTTAAGAGTGAGGTGTTAGTGCTTTGCCTGA GATTAGCAAAGCAGAAGAGAAAGGGGACTGAGACATAAATGGCTCCCTCTATTAACAGCCATGTGGGGACTCCACTTAGAAGTGAAATCTCCTAGTT CATCAGGACTTCAGATGACAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCTGATATTTATTATTTTTAAACATAATTATTTTAAAGTAATTTGTTAATATTCC ATTGAATGAGACCCCTCCTTCCATACAGAAGACATCATTTGTATTTCTCTTCTCACTGGTTCCTAGTACTTAAACACTGTACTGACTCGACATCATT GAGTCAAAGCCACCACTGACTGCTGAGTGATAGACTTTACAGAGCTAAGAACTTTGTGCACATTATAACTCATAACTACTTTGGTTGTTGGACTATG CTTTTCTTTCTATGAAAGCAGTGTCTCTGTCTTGCTTATACTTATGATTCTTGATTCTTGTTACAACACATAATAGGTGGGAAATCTGTCGGGTGAA ACTAAATGCAATATAAATAAGATCATTATAATCCTTAAGGGGTTTTTAATATACTTAGGTTTAGAGAAGATGCAAGTCGTAACTTCTAGTTGTATGG GAGCTTAGTCGGACCTTATTCAAACAGCCCTTTATTGGGTGCCTACTAGGTACCGGACATGGAACTGTAAACATGAGACAGTCTTCAGCTTGAACAG GGGCCACATCTCACCACCTTCATCGCCACCTCTGTGATTCATGCTACCAGTATCTTTTCTTTTGTTTAGGACAATGAGATTACAATGTTAAACCCAA CATTGTAATCCTAACTGGTCTTCCCTCATTCACTTTTCTCCCCACAGGAAAATCTCAACTGTGTCTAAAGGGATCCCAGGATACTCCAGTCAGAGCA TGTAGTTCCCCTGCTCTCACACTACCAACGTCTGCCCACCTGGGGGAGGCAGCAGGCTTGACCTTACAAGTCTTCAACTGGGTCTGAGTCAAGAGGT GGACTGTATCTTCAGCCCACTGAACATTGAGCGACTTTGTGACTTTCTTTGGTCAATAGGATGTGGTAGATGGGACTCTGAGCTAGACCTGATCATG GATGTTGGCAGGTTCTGAGTTCTGCCTTTAGAATCCGGCACCTGCCAAGGGAACAACAGGCAGGATGGCTGGGAGGGTGGCGTGGGGTGGGCCAGGG AGAACAGACCAGTCAGTTACCAACCAACTCAGCAGCTGAGAGGTCTGGATGAGATCAGAGCTACTGTGGCCTTCTGGAATCTTCTGAATGACCTACA AACTCAGCCAAAAGCATGCCTGTTTAAAGCTCTCGTGAAGTCCTTGGTATGTTACACAGTGGAAACTTACTGATAAACTGTCTCGTTCAGGGGAAAA AGTCAAGTGTTTTGCCTGGCACATGGTGGGTGCTCAGGGGACGCTTGATTAAATAAGAAATTCCCAAATGCAGTTTGCCTTCCAGTGAAGAAAATAA GTTCTAAAACAATCAGCGGCTACGATAAGTGCTCTGAAACAAACAGGCAGTCGCAGTGGCTAGATCTGAGGATCTAGGGAACGGGGCACGGGCCTGT GGTTGGTTCTCTGGTTACTTAGAATGAGGCAAAACTCCTCCCAATTGACTCCAAGAGCCTTGAGAGACGTCCCGGCTGATCCACGTACCAGAACTTA TCCCCTACCAGTCCCCTGCCACTCTCAGGACCTCTGATCCGGAGACACTGGGCTCTCTGGTGTTCCACCTCAGGTGTGTGCCTGGACCTTTCTTCAC TTAGCCTCTCTGCTCCCCCTCAGGTTCCTGCTCACGTGTGACCCCTTCACCAAGCCCTTCCTGGCCAGCTTACAAAAGTGGCCACTCTTCGAATTCT CCTACCCTGCTCTATTTTTATCTGTGACACTTGACACTCCCTGATGTATTATGTCAGCTCAGTTGTTTTACCTGTCTGCTCTCACCACTAAATACAA ATTCTACAAGGATTGACTTTTATTATTATTATTATTATTATTGTTATTGTTATTATTGTTATTATTATTATTTTGATAGGTTTGTCCTTAGAACAAT ATTGTCGTCAGGCAGAATTGTAATCAGTGGATACAAAAATGCTTTAGGAGCCATAACATATTGTCAGCCCTCAGATTAATCGAGGTGAGCATTTGAG CCACACTGGGAATAGAGTAAGAGCTTTTATTTTAATATGTGTGCGTGTCTTGCCTGCACATATGTATGTGCCCCGTGTCCATTTCCTGGTACCCGAG GAGTCAGGAAGAGGACCCCTGGAACTGGAGTAACAGATGATTGGGCCACTGTCTGGATGTTAGGACTAGATCCCAAGTCCTCTGGACGAGCAGCCAG TGTTCCTAACTGCTGAGCATCTTTCCAGTCCCCAAACTTTAAAAAAAAATAGCCAAAACACTGGGATGAGAATGGGACTGTTCAGTAAAGCGACAAG CGTGTTCGTGTCATGGGACACATGCCAAACACCGCCACTCCACAGCATGCTTTACAGAGTGGGGGACATTCCTATTCAAATTGTCATCCCTCATTGC AGTAGCCCTGAAAGGTAGTAGGTGGGGCAGGTTTTAGGTGTGTGTGTGTGGTGGGAGGCTGGGGGGGGGGGGAGTAAGGGAAGGGAAGTCACTGCAT TCTCATCATATCGATCTGACTCCAAGTCCAGAGCCTCTGTCCCTCATTTTGACGTTCTCTCCTTGTTGGGTTATGACGTCACTGACTTCTGAAGACT CAAGGTCAACCTTGAACTCCTGAAGGAGCCCCTCCACAGAAGGTAGGTATCCTTTCTCTAGGGAGAATGAAAGTGTCTTGCTAAGAGGACAGGGGAT AGATAATAAACTTCTTTAGCATCGATTCCAGAGACTCCCCGAGACTCTCAGCTAGCCCCAACGTCTTGCTTGGTCATCTGTAAAAGGCAGTGCCCTC CTTTCTTTTTGTCCCCAGCCCACCGAACTGTCCTATAGGTGAAGGAGGAAGGCCGGTCATAAAACAGGATGGGCAGTTGCTTTCGGGTGAAACCCAG AAAGGGTCCTCAGGCTTGTCGCTGACTGTATTTAGATTTAAAAATCAAGGCCTGTGACCTGGAGGCTCTTTCCTGCTGCTCTCTGCCATGTTGACAG CAGAGAACTTGCTAATTCTGGCCGGGGATTTTCCCTGTGTGGCTGTTTTTCTTCTTTATCTTCATCAATTGAAGAGCGCTCGCTCTGCCTTTCAAAC TGCCTGCCGGAAGATACTGGGGGTTTGTGTATTTTTTTTTCTTTCACCTAATTCTGTGGTCTTTTCCCAGATGTGTATTTTCTCTCTACCTTCTTTC TAACTCCAGCAGTCCGTGGGAAGGGAGGCTAAAGCTACAACCTGTATCTTTCCCCCCCCACCCCCCATGTGGCTTCCAGATAGAAGAAAGAAGGCAT CTGTGGGGAGCAGTCCCTCTGCACCCGAGAGAGAGGAGGACGCAGGGGTCTGTCAGAGGTTGCTGTTGGGCAAGCAGGGGAGGTACCTGTGGAAGGT GGTGTGCTGGTGGCCCCCTAGCAGTCAAGAAGGGGAGCCAGCTAGTGAGAAGATCGCCCAGAGGCATCTGGGACGGTGTGGGAGAGCCCGGAAGATT AGAACCATGCCTCACAGCTCCGACAGCAGTGACTCCAGCTTCAGCCGCTCTCCTCCCCCTGGCAAACAGGTACCCCCTTCGTCCCCCTCCCCCACGC CCCGCATGCCTTGCCTTCTGATTTTCCTGGGGTGGTAGAAGAGGGGTAGGCTCCCTTGTCCTGCCCAGGGAGCTCTGTCTGGGGAAGGAAGTAGCTC GTGGCAGGAACTCTCTAGCAGACTCTGGACCGTGTGGTGTTTGCTATACAGAGGTCCAAGGGCTGAAGCTTCGCATCCCGCCACAAAAGCCTCTCTT TCCAAGAGGTACCCCTCGTCTCTGCCACTTAGGTTCCCACCGTGAAACTTTCTAGGAAGCTGGGGGCAGGGTGAATATCACAGAGCTTAGAAGTATG GTCAACCATAAGCAGAGGAATGTTCCAGTAGATCGCTGCCTCGGGCTCCACCCAAATCCCTAGAGTTGTAGCTTTCCAGGAAAAACCAAGCAAGTGG CAAGACAGAACCGAGGTCAGGGAAGAGAAATATAGCAAATCAAAGCAAGGTAGACAGGAGGAGAAGAGTGGCAAGATCTGCCTGCGGATTGCCTCGG TAACTCCAGCAGTCCGTGGGAAGGGAGCTAAAGCTACAACCTGTATCTTTCCCCCCCCCACCCCCCTGTGGCTTCCAGATAGAAGAAAGAAGGCCAT GGTCCAGGAGGCGTGTCAGAGACTTTCACTAGTAGCTAATATCATCCCTGAAAAACCAGGGATGGAGGGAAAGATTCTGAGACTCTTAGACTCTTGA CTGATACCAAGCCGAAATGTCTCAGACTGAAAGATGCCTCCGATGGGATGCCTTTCTCACCTTGTGGTTTCTGGGTCTCTCTACCACGTTCCTGATG CCCCTTGTTCTAGACATTTCTCCTCCTCATCCAACATAGACCCACGGATTAAACTTTTTTACATCTCATCTTAAAAACTATATTCTTTCCTTAGCAC ACATATTGGGAGGGGCTCAGAGGTAGAGTGTTTGGCTCACACACATCCAGGGGGCTGCAAAACGCTACAAACAAAATAAACGTAAACTACCTGACCA CCGGCTCCCACATCTGTCACAAGCCCTCACCAAAAGCCATACTGGTGAAGACCTCAAGAGGGAGATAGTCCCTCGCTCACGATGGTATCAGAGCAAC TCAGACTGCCTGGAAGATGGTACCCCAGTCTCTTCTTAAGAAGGAAATTACTCACAGCTTCCATGGCAACCTAGTCCCTTAGCACATTAAAGGAAGA ATATATCCTTGCCCTCTCTAACCCAATGTCCGTTTTGCTAGAATGACCTGGAAAGTTTGAGTAAAGAGGGAAGGGAATCAGAACCTGACCCAAGGTC TTTGCCCCTCAGGCCAGTGGAGGTAGGTGACAGGGTGGGGGTTGCAGAAGGGTTCTCTTCCCTGATCTTCTATAGGAGATACTTAGTTTTGGTCTCA AAGAGCACTGTGTCCTCCAAAGCACCCGTCAGTGGCTCACTAAAGCAGGCGACCTGCACTTCATAAAATGATTTGGTGGTGGTGGTGGTGGGGTTAC CTCATCTGTAGCAGGCATCATGTTCAGGACTAGGAAGGTCTCAAGATGTCGCACAATGATGGACCGAATAAAACAGATCTGGGCGGCGCCCCTCTGC CTAGGGGTGCAGCACAATGAAATTAATAGTCAAGGGGGAATTCTCAGAAAGGATTGAGCATCAGTGCCAGAAAGATGTCATACCCCTGGATGTCCAT GAGCTCAGGGATCAGGGTGGAGAGCCTCAGCTTCGATACTGTGAAAATAGAAAAGACGGTGCCTGCTCAGAAAGCTGGGGAGTTGAAGCATAGCGTC TCCGAACGCGCTTGTACAGAAGTTGGCACATGGTAAATGCTCAGCGGAGTTTTCAAAGACAACAGCAAAAGGAGCATCAAGAAGGTTTAGCATGTGC GCACACATGCACATATATACATGCACACACACTCACACGCAGCATACCTCACATGCATACATATGTATACATCATGTATCACATCACACACACACAC ACAGAGTGAAGCTAGAACAGCTCTGGAGAGAGCAGAAGTGATGGCATCTTAACTGGAATTTCCCAAAGTAGCCCTCCTGAGGCTTCAATTTCTCTTC ACTTTTGAGTAGCTTTTGATCATAAGAAGACCATAGGAGACCCAAGGGTGGGTAGCAGGGAATGCTGAAGAAAATGTCTTTGGGTACAGGCCTTTTG TAAAATAAGGGGAATGGACAATACAGAAAGAACTGAGGACCGGGGAAGGAAGGAAGGAAGGAGGGAGGAAACCAATGTCCTATTTGACTAAGAGGAA CGATCAGACCTACCGTTGATATCTCTGCTTCCTAGGACTCATCTGATGATGTGAGGAAAGTTCAGAGGAGAGAGAAGAATCGCATCGCTGCCCAGAA GAGCCCGACAGAGACAGACACAGAAAGCCGACACCCTTCACCTGGTGAGTACCCACACTTCCTACCATGCTCCTGCCCTTAGGCTCTGCGCCCACAC TGGAAAGGGCTTCGCTCTCCCATGCATGTATGAAAACATTTAGTAGCAGAGAACAGCACTGGACACTGAACCTTTCTGGCCCAGGAGACTGCAAGGG TGGAAAGGGCTTCGCTCTCCCATGCATGTATGAAAACATTTAGTAGCAGAGAACAGCACTGGACACTGAACCTTTCTGGCCCAGGAGAGTGCAAGGG TAGATGTGTGGGATGTTGACAGCCTCAAGGCTTCATGGGAGGCAGAGCCACCTGTGTGGAAAGGGACAGCAGAGAGGGTGTCGTCCTTCCTGAGCCA CTGTGAGCAGAACACTGATGCTGAGAGGAAGTTAGGTGTTAAGTGCTTCAGGGAAGCCATTCTTTCAGAGCTGCACATCTCATCCCTCTGGAAGGCA ATGGTCTGCCACCCAAGCACACTTGCCTTTGGGAGAAGGAGGTCGATGATGCTGCCCTTATTTTTTTTCCCTGAGCATGGAGAAAGTTCTGTGTTGA GATTTACATTGTTAATGGTCTCTCTAGGGTCTGCTAAAGACAAAATTTTAAAGCACTTACTTGGGACAATCACCATCCTGGTCTAGCAGGGAGGGGA TGAACTGCAGCCTCACTTGGGAGACCCAGGGCGTGGACCAGCGACCCCGAGTCCTGACTGGGCGCAGTGTTCCCACCCTTCATACCTTTCCTCTTAA CAGTCTGCTCCTTTCACTGTGTTCTTGCTCAACTGGTCCATCTTCATCGCATCCTTCTTCCTGCTCTTCCTCCTTCCTCCTGAAACATTTCCAAACT GCTAATATTCTAGAAATTTCCTAAAAGTGCAAGAGATGCCAAACCCAGATAAGCTGATAATGATCTGATGTTTAGCATGGCTAAGGGCTGCTTTAAT TTTATCAGGGATAAATTATCGGGGGCTGGGGAAATGGCTCAGGGGGTAAAATGCTTGCCATTCTAGCATCAGGGTCAGAATCCCCAGAACCCGCATG ACAGTCAAATGGGCAAGAGGCAGAAGCAGCAGGTGGACATCTATGAAATTGAAGCCAGCATAGTCTACACAGTGAGCTCCAGGATAGCCAGGTCTTC ATAGAGAGCCCCTGTGTCAAAAGAGAAAAAAGAAAAAAAAGAAAGAAAAAAAAGCTGAAAAGCTTAATGGATGTGGCAGCCTGACAGTGTAATCCCA GCTCATGGGAGGTGGAGATGGGGAATCTTAGAGTACGTTGGCTAGCCAGACTAGTCAAAACAGTAAGCTTTAGGTTCAGCAAAAGACTCTGCCTCGA TTCTCAATACGGAAGTTGGAAAGTGATGGGAGAAGATACTGACCTCAACCCTGGGCCTCACACACGCATGTGCATCTATGTACACGCGTGCCCACAT ACAAGAAAAATACATGGAAACACCACACGCACATACACATGCAACAAAAGAATAAGTAACATACAGTTTTAGAAGACAAAGGGGAGGATATCGCCAC TTCTTTCAGCCTAAGGACAGAGAACGGTCTGCCCTAGTCGCTCTGCCTGTGCTTCTGCTCTGTTTGATAGGTTCTTAATATAGTCTCCAGTACGTGC TAACATCATTTTCAATTGGCAAATATGTGTCAGACTAACAAGAGAAAGAATAAACAGCACTCAGCACAAACAGACCAACAGTCTGAGTGTTCAGTGT CTGTCCCGGTACTCAAACCCTTCAAGATTTCCTGGGGGCTTAAAAATCTCACACTATCTGAAACTGACTTTTTCTATCTGAGTCTGGTTCTTAGTTA ATATTCCATAGAGCAAGAAAGCCACACTTACGATAAACTCCGTTTTGTTTGTGCAAGTAGACAATGTCCTTGATGGGCAAACTCCTGTAAGCTTTGT AAGTTTGTAATATTAAAAGAAGGAAGCTGAGTTCAGCCTCTCTCTGGCAGGGAGGCCAGACTTGAACCACCGCTCTGCCGACTGCTGTCTGTGTGTC TGGACCCACAAGCATTCTTCATGGTCCTTAGCCTTGGGGCCCTTATCTATAGAATGGGAAATGACAGGAACTGCTTATAGAGACAGTGCAGGAGAAA AGCTCAGTATGGTGCCTGGCATACAGTAAATACTCAGAAGATTCTGTGCAATTAAAGTTATAGTAATAGTGTAAGAGGCGTGAAAACTGAGACTGAG CAGGCATACATATGTACATTGCATAATTTTATATAAAAATGTACGTGTATTTCCCAGTATGTATATATGCACATATTACATGCATGTATTGTGTGCC GTGTGTATTGTGTGTGTATCTACCATGTGTGTGTGTGTGTGTGTGTATCGTATGTATGTGAGTATGGGTGTGAGTGTGTGTGAGAGATGCATGCATA TGTGTGTGTGTGTATACTTTTTCTCCACATCATCTCAGTGGTGAGAGACTTCTTAACAGCTGTAAAGCTCATGAGACTCCCTTGCCACACTCACTCC CGGCAGAAGGTCCCCAGGGCACGCCCAGTCACCTCTAATAGCAGAGTGCTGCCTCCCTCTTGACACAGGAGAAGGGCCTCCTGTCTCTAGCTGCAGG CCACCTTCCTATAAACTCAGCCCCCTGGTCTCTGTTGCCTAACTTCTTCTGTGAGAGCATGAGAAACTTACAATGAAGCATTTTGAATACCTGTCTT GTATTCATGCATGGCGCGCTGATTGTTTTTTAAGTGACAGAGGTGGGGAGGAGCCTCCTGCGACAACTGTGTTACAATGTCCCCAGCATTGATTAAC TGCACATAATTCATTTGTGATTCTGTTCCGATTATGAGATATACGTGATGGTTTCCCAGACACAGATGTAAACATAAGATAATTAGGATGGCATATC AACCTAGTCAGAGAGGTCGAATTATCTAATAAATAGAGTTGGGACACCTGGCAAGTCACTTGAAGAGACAAAAGGCCAGGTCTCTCATTCCTTATGC AATGCACAGACAGTTTAAATATTTTTAAAGGAAACTAAAGAAGTCTTGGGGGAAAATATGTAATTTGGAAATGTACCTTGGCATGAAAATTTTTCAA ATAAGATAGATAGAAAATAATAAAAGAAAATTGATATACAAATGTGATTTATACATGCATCAAAAAATAAAAAAATTTGGCTGGGCATCCTAATTGG GCTAGGCCTTCAATCCTAGCACTTGGGAGACAGAGGCAGGTGGATCTCTGAGCTCAAGACCAGCTTCATCTACATAGTGAGACGCCCATCTTGAAAA AAGGATGAAGTTTACCCCCCCTCTTTCTTCCTTTTCTCTCTCTCTCTCTCTCTCTCTGTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCTTCCTTCC TTCCTTCCTTCCTTCCTTCCTTCCTTTCTTTCTTTCTTTCTTTCTTTCTTTTTTTTCCTTCTTTCTTTCTTTTTTCCAAGACAGGGTTTCTCTGTGT AGCCCTGCCTGTCCTGGAACTCACTCTGTAGACCAGGCTGGCCTCAAACTCAGAAATCTGCCTGCCTCTGCCTCCCAAGTGCTGAGATCAAAGGCAT ATGCCACCACTGCCCGGCTGAAGTTTTTCTTTCATTCTTCAAAATATTATATACAAAATCAAAGGCAAATGGAAAGCCAGGAGGGAATCATCTAGAA AATTCATGAGCCAGAAAGGCAGGTTTTACTACATATGTGGGAACTCTATGGCGAGGGAAATGATTGATCTTTATTAAAAAAAAAAAAAAAAAAAAAA AGACTATAAAGTGAGGGAAAGGGAGAAACAGAATGTACCTACACATGTAAGGATGCGCCAGGCCTCCTTGGGAAAATGCCAATGAGGGTGAATGTAA GACTTCCTTGCCAGGCTGACAGAGGTGAAAGATGGAGCTGACCCAGGAAATGGCCAAGGGAGACGGAGAGTGAGCATCGCATTCCCTTAGCAGGGCA AGTTGCTATAACCCCCTAAGACGGCAGCTTGAGCAGGCTCACTCAGGTGGCAGGGGCACCTCCCCTGTCTCCCAGCAGGGTGCTGTCCAGAATCCGT CCACACCACAAGCACAGCACAGAGGTTGTAGCTCTCTGAGCTGAGTGTGAGTCATTGTTGCGATGTGCTGCTCTTGGTGTCTCTTGGTTTTTGTTTA GTGGCACTGGGGATTGAACCCAGGGACTTGTACACCACTGAATGACTGGAAACTAGTTACATATTCATTAGGAGAATGGGGGTTGAATGAACACTAT TGGTCCATTCTGAGTGTGCTGTTATGGGACTGTTAAGTGAGTTGCTTCTGAGTGTGGTAAAACTATCGTTTTCTTTTCTAAAACAGTTTTTCTAAGT TATGGAAGGTGGGGTATGTGTACATGAGTGCAGGTGCCCATAAAAGACAGAAGGGGGTATTGGTCCCATGGCCACAGGTACTAGAAACTGAACTCGG GTCCTCTGCAAGAGCAGTAGATGCCCTTAATCACTGAGCCATCTGTCCAATTCCTCTTTAAAGCTTTCTATGTTGCAGTTATTTATTGTTTGTTTGT TTATTGTGGGGGAGTGCATGCATGTGTGGATGAGTCGGTTCTCTCCCTCCGCTGTGTTGGGTCCGGGCATCGAACTGAAGTCATAAGACTTGGCAGC AAGCAGCCGGGCGTGGTGGAGCACGCCTTTAATCCGAGCACTCAGGAGGCAGAGGCAGGCAGATTTCTGAGTTCAAGGCCAGCCTGGTCTACAGAGT TCCAGGACAGCCAGGGCTATACAGAGAAACCCTGTCTTGAAAAACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGACTTGGCAGCAAGCACTCT CACCCCCTGAGCCCTCTTACCGGTCCCTGGTTCCCAGACTCTTAAGGAAGAAAAGTGCAAATGTAGCATCTAGCTTGCGCCAAGCCACACTTTTTAA TCTGTCTGAGCATAAGTATACAGGCAAGTTTCAAATGGATCACCCGAACTTATTAATATCATTTTCAAAAGGTCACACTGAAGTTAAAAGACAGGAA AAGTGTCCTTTGCATTTTCAATCCTTTTTTATGTCAGTTAGGAGTAGCTAAGATTTGAGTGACTCTAAGGTCCGTGGTACTAGATGGAACACTTTAA AGAATGGCAAGTCGTTTTCCTGTGGCCAGCCAGCCAGTTGAGAGTGGGAGCCTTCTGGAATCTTCTATCATAGGGGGATTTTGAGTCAATGTCCTGG GTCAGGGTTGGGGTGGGGGTGGGGGTGGGGGAGAACTGAGATCAGTTTAAAAGCATTGCTCTGGAGAGGGGCTCCAAGCAGAGGAGGTGGGGGTTGG ACAGCAGAGTCTCCCAGAGTGTGCTGTTGGCAAGTGGCGCCTGGTCTCCAGGTTGCTTGGCCATCCGTGCTGGATCTGGAAACTGGAGTACGAACAG GGTGGCTCCTTTCTGTGAAGATGAGGCAGGATATGACTGCTGTGGGCTCCTGATTGTAATCTCACCACAGTTCAGGACAGGTTGTCTGTGATTTTGT AAAATCACATAAAACAGAAAAATCATGTAGACTGAGCTGATGCTGTGAAAAATGAGGACCATTGGAGGAAATTAAATAATTGAGAAATTCCCAAAGA TGTTAGCTCCCAGGGACACTGGGAGCAAGTTTTTCAGCAAGGCCATTGCTCTTGGCTTGCTGAGGTGGCGGGAAACGAGGCTGTGAGGTTCCTCCAA CATTTCTCATTCTCTGTCTCTAGGAGACCACATCCTGAGGTTTATTAACATAACAAATTCATAGATCTGTAAAACAATAAAACATGAAGGGACATTC TGGCTAGTTTCACCTTTTAAATGCTTAATCTAGAGCCAGTGAATCAGCCGCCTCCCTGGCATCTCTGCCTCTCTGAATTTCTATTTAAAATATGGTC ATTAGCTGGGCATGGTGGCGCATGCCTTTAATTCCAGCACTCGGGAGGCAGAGGCAGGCGGATTTCTGAGTTCGAGGCCAGCCTGGTCTACAAAGTG AGTTCCAGGACAGCCAGGGCTATACAGAGAAACCCTGTCTCCAAACACACACACACACACACACACACACACACACACACACACACAAAGGTCATTG AACACCTGGCCATGGTCACGCTAAGTGCGTTAAGTGTCCTACCAGTGGGGTTGCACTTGATCTGAAAAAACAAATTCTTTGCATTAATCAATCTGCT GAAGGTTGGACAGCTTGAACTTCAGAGCCCTCCTTTGTAAACATAAACATCTATCTGTATCCTTGCATCTCCTGCTAAGGTCTTGTTTGTCTTGTTT CTATTTAAACAATACACTCTGAAATTCTTATTTTTCCCTGATCATCTTAGGCTTGGTCAAGAAAGTAAAGAAAGGTCTATCTGTTGCTGTCTGTCTA TCTGTCTGTCTACCCTCCCCCCCTTTCTCCCCTCTCTCTCTATCTCTCTATCTGGCTGTATGTGTGTGGGTATATATAGATCTTTATATAAATATGT GATACATATGTATGTATAATATTTATACACTAGTTTTTAGAAGATTGTTCCATTTTAACAGTGTACACAAGAATAACCTTTGGACACAGTCCTTCTC ACTATAACATTGTAAGGCAAAGTCCATAGATGAGGATGCTGGAAACATGGATATCTGAACAGCAAACACTTTATGGGTGTCATAAAATTAGGCAGAT GGTTAACAGGATATTTAACAGACTGTGATCCACTTACGCAATAGAAATTGAGTCTGACACTAGAAGTGGCCATGGAGATCTTTGTGTATAGACTTAG AAAGATGTCTGCCAGGCTGAATTGAGCTAATCAAGCCAGGGGAGTGTGCAGAGCACCATCTGCTAATGTGAAGCTTGCAAGGTTTGGGGATGGAAAC ATAGTCTCCAAATTACCAATGGTGGTTACTTCTGAGTGCCTGGGTTGGGGTAGCTTGCCTTCCTCCTGGTGCTCTTTGCAGTGTTATTGTGACTTAA ATGTGCTGTTTAAACAATCAGAAATAGTCCCAGAGTCTTTACAAATCAGCTATTTTAGTTGGGGAAGAACACACCAAGGCAATTTACCACCTCAACT GCTTATCCAAGGACGATGGGCTGCTCCGTTAGGGTGGGAGGGCCCCAGACTTGAGGAATGTGTGGCTGAACTGGATTGTTAGTACCAGCTCACAACC

[0300] TABLE IX MOUSE NOMENCLATURE ICSGMM Irf4 Celera mCG4922 HUMAN NOMENCLATURE HGNC IRF4 Celera hCG20902 MOUSE SEQUENCE - GENOMIC ATGCTCATCATCCTTGAGGGCACACCTCCCTTGCTTTTGCCCTCTGAATCACAGCCTTGTCCTCCTTCAGCATGTCCTATCTTTCCATATTTTACAC CTCTATCCAGGCTGGTTTTTGCAAATTTGCCTGCCTAAAATTCCAGTCGAGCTGTATCACTTGTAAGGATAAACTACTAATATATATGCCTTGCCTG TTCTCTTTCACTCATGAATGAACAGTCCTCACACTCCTATCCCCCTAATATCTAACAGAGATGCAGCTCCCAAACTCTACAGCCTGAATCCCAGAGC CTGAGCTAGCCCACGAATGCATCCAATCCCTGTGGTGCAGAAGAACCCATGCTCTGTCCAAATCAATCACCTAAACGGTTTAGAATTTCTCTGTGGT CTTCTCTTTCCAGTGCCTAGGTCTCCACCCCTACCTCTGACTGTTTTTTCTTCTACTAGCATCCCCTGTCATACTCTTAAGATTTCTCAACCATTCT AGTCGTAACCTAGCCTGTTCTTTTCCTTCATGTCTTATATTGAAATTCTGTGACTCTGAGGTTCAGAACAGAAGTCTTCTTGCTGGGGTTGCCTATG GTTCTCTCAATCATTTCCACTCCTTCCCTACTTGGTACTTTCCCAGAGAATGATACCTTTTGGGCAGTGAGTGATATATACCCAGTACTAAGCTGAG TCACTGTCAGCATACTCTTTTAGGCAACCUTGGGTCTTGGCCATGCCTCATTGCCTTTTCCTGTGCCTCACAGGAGATAGAATAAATCACAGGACTT TGGAGAACGTCACAGTGGTCCATGCAGTTGACCCTTGTAGCTTGAGCTTTGGGTCTCAGAGTGCCAGAGCAAGGGAAGATAGAGCACAAAGATGTGG AGATGTGGAGTCACAGCAACAGTGTCACCAATTCTAGAACTATAGTTGCAAGCACTACCTCTGCTGAAGGCAGTTGAATACGAGACAACATATCATT GGCCTTTGGAGCAATGCTCAACACCACCCACGGCAGGACACTTTGCAGAGCAGGGACATGGAGAAGCAGAGAGGTGTTCGCTGGACTTGGGAAGGAT GCCTCGTAGCACAAAAGAGAAAGGAAGAGTGTATGAAGGGCAGGCTGGATCTTCCAACACAAGAGTAGGGGCACCAGCTTACTTGTCTTTTAAAGGC CTGCCAGCACAGTGAGTCCACATGCCCTGGAAAGTCATGTTTCTTCTTAGGTTATATTGTGGCATGCTGGGATGCTTTCTCCTGCTGGGCAGATGGA AAAGACAGTAGATGGTTCTCCTTGTAATTTTTAAGTTTCATCTGATGTTGAATTACCCCCCACCCCCCAGGATGCCTGAGTTCTACTCAATAAAGGA GGGGCTAATTTAAAACATATTAAAAGTCAACACATTAAGTTTCCAACGTTCTGTGTAGCTCATTCCCTCTAAGCATGCCTATCTGCAACCCAGAAGA ATCCATTGTTTTGCATCTGAACACACTATCAGGGACTACAGTGCACCATGACTGTTCTAGGTCTAGCAGAGTGTATCTGGTGAAGAAGTCTGCTAAG AATACTCGCTGCTGGCCCTCAGGGGCTTTTCTTCTGTGTGGACTGGTTTCTTTTATGCTCAGTGGATTATATCAAATAAGAACAATATATTCTGTAA TCACAAGTAGTCAAGCCTGTGTACTTATGCAGAGGAAACTGCCTTTGGATCATGAGTTTGTAAAGAGTTGAGGGAGAGGCACAGTGTTTAGATCAGA AGGTGATCTCCAGATGACGTTTTACATAGCCCTGGTTAGTCTGAGCTGAGGAGGGGCCAGGTTTCCTTCAGTCGTGCTGAAGACTTCAAAGGCTGGG CAAAGAGACCTTTATAAGAAGATGCTTCTCAAGGCACATGAGAGAAATAGTACAAGGAGACCCGGAAGGTAGAGAAAGAGGAAAGGAGAACAGACTG GCTCACAPGCTCAGAAGTGAGGACGACTCCATCTCACAGGGGAGTGCAGGGCATTTCTGAACAAGTTTGTGCAATTCATACTCCTTGTGGTGGCTAC CTGATATGAAACAACAACACATTTTATATAAAATAATCTAAATCACATGTTCCTTTAGAGATTGCCAAAATGTTTTGTATACTGTCGAAAACTAAAA ATTGAATGTCCACAACATGACCTATGTTCATGCCTACAAUTCCATTAGTACTTTCACTCAGTCTTTAACGTTTTGTATACTGTAAAAACTGTTCCTA AAATTTGAATGCCCCCAACATGAGCTCTGCCCGTGCCCATAGCACCATTAACACTGCCACTCTGTCTTTCCAGAATTCCAAAGCTTGAGACAGAATG CCTGAGGAACATCAAAATGCAAAGCTTGATGAGTACCTGGCCTTCCTCTGTAGTAGCTTTAAGGGAGACAAAACAAGCACCCTTTGATGGACTCCAT AATTGTTTTACTTACTCTTGGACCATGGAAACAAACTACAGATGGGGCCATGGGAACAAACCACAGATGGGGCCTGAAACCTCCTCTGAGAAGGGAC AAGTGGAAAAGGAGACACCAGATGCTCGAATATCACATTAGTTTCTCTGTGAAAGAAGGTGGTCAATGTGGGTTGCAGGTAGGGCAAGGGCATTGGT AATTGTGAACCATGAGGTATAAAACCAAGGGGACATAATACTTCTAAGCCTGACTTCGTCTACTTGGCTGGGCTTCTCAAGGACCAAGATGAGTCTG AGGAGAGGAACAAATGGAGGTAGACAAGGGGATCCCATCCTGGGGGGTCAACCAAGGGAGGTTACATCAGCAGGCCAAAGCCTAGAAACACAGGACA GTCTCTAAGTGTGGGGTCAGGCTGTCCTCAATCCCAACTGGTTTCATTGCCATCTGGGCAAGTCCAGGTGACCTCCCTGATGCCACCATATCCTTTT CTGAAATAAGACCATCGTCCTGCCTCACTTCCCTACCTGTTCATAATAAGAAGTGATTGAGAAAACTGTAGTCTGGTACAGTACAACTTCTCTTTGG AGTAGCAGACATGAAGCCCATTGTCTGCAGGCTGCCACTGAGCTGAGGGCTGGGCTAACCTGGGATTTTCCTCTACCGTGCCCAGCCTGGAGGAGTT CAGTACTTCTAACAGAGTTCTACTCATAGGTGGTTTCTCATATGGTAGTTCCTTTGCCCTCTCTGACTAGCCTCATGCCTGTGTCTACTGTGGAGAG TATCTGCCAAAATCTCAGGGAGGTGCAATGATCTCACCCAAGTCATATTTCATTTGCTGACACTCACTGGCTTATTGCATTATGGATAAAAGCACAC GAGACACGCATGCATCAAACATTGTACAGCTCCCCAGTAGTACACACAATTGTTATGTGTGGGGCTTTTTTAATCACCTAAAAGATAAGTTTAAAA TGAAAAACGTTGATCCCCTAATGTGGGAAAGAGCTTGTGTCTATTTGAATGACATGAGAGCTAAGACTGCTTTGGATCAGAAACCACATCCTTTGCC TCTCTCTCTGCCTCAGCAGAACCAAAGAAGCTCAAGAGACCCGTTTCTGTGTGCTCACGGTCATCAGATACAAGCAACGAAAGTTCTAATGCAACTG TGAAAGTTTCTCTTTTTGTCCCTTGTTGTAGGATAATCTGCATTAACAAACTGTCAAGATGTTGAAAAGGAGATGTGGGGGAGAAGGGGAGTGAGAC AGGACAGGGAGGGGAAGCAAGCAGGTGAACTCTACACAGAAAATAAGAAAGGTAGAAATTCCCTGCACTGCACTGCCCTGTGTGGATGCACTGTCCT GCATGGATGCAGGAGAAACAGCCCAGGTGGCCCTGGGGATGAAGGGCTCTTCCTTTGCCTGCAGAGGGAACTGCCATTCCCAGGGGCCCTCAGCTCT TTCTATGATGAAAAGGATAGTAAGGCTTTCCTTCTGCAAGTCACCAGTGCTCAGATTATCTGCACCTCTCCCATCCCATCCTCTGGCTGTCCAGAGA GCAACAGGCAGGGTCAAGGGACTAGATGGCCTGGCTTAGGCTGTGCTGTGCATAGTAGAGGCCTCTACAAAAAGGACTAACAGTACAGATGTCTCCA AATTACCTTAGTTAGACTTTATATCTTTAAAAAAAACTATAATGGCATGAAAATGATACACATCCATTAAAATTATCCTTCAAATTCTGAAGACAGG CAGTTATTGTTCATACAATGCAGAGGGCCATGGOGACCCACTTGGAGACCCTTAGTTCTTGTTTGGCAGTGTTGATGGGCAACTCTAAAGGTAAGTA TGGAATCTTTTGAACAAGGGCTTGATGGACAGCAATTCAGGTTCATCATGGCAAAAAGCTTGTTTTGTGATGTCCTTGGTTGAGCAAAGGGAGAGGC AATCTACTAGCCCACTTTTCATGGTCTCCTTAAATGCCTGAAACAAGAGAGAGAGAGAGAGAOAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG AGGGAGAGAGGGAGAGAAAGAGGGAGGAGAGAGGGGGGAGAGAGAGAGAAAACACAAATATTTATGTTCTATGAAGCTACTTTGTCTAAGATCTATA TGTATATCTGGGTGCTGTGATTTGAATATCATATAAATGTATATATGATATTCAAATCATATATACATATATATTTATATATGTATATACGTATATG CATGTATGCATATATGTGTGTATATATGTGTATATGTATGTATGTGTATATGTGTACATGTGTACAGTGTGCATGTGTGCATGTGTGCATGTGTGCA TGTGTGCATGTGTACATGTGTATATATGTATATATGTATATGGGCTGGGAGCATGATGCTTACAACTACTGAGAGGTTGTTTTGCTGAATCATAGC ATGACACAGGACACTGTGTGGTGATACAAAACAAGCAGCTAGCTAAAGCCTTTCTTTTTGATAATGCCTCTTCTACTAAGAAGCTTGCTTAGGACTC CAGCCAATTCTAAAGACCCCACCCCTACCAAATGCATTTTCACTGAGGAATTAAATTGCTAACCCACAACTCTGAGGGAGGAAACATTCAAACTACA GTATCTGATAAACATTTGATCCTCAGACAAAAGAGTTTCACATATTACTTGGAGCATACTTAAACTGTACAATTATACCCATTTTATCAGAAAAAAA AATCCAAATATAATTCTGAATTACACGCTTTTATGTACCACAACTGGCAAACCTGCTCCAGGCATAGAGGTAGGCAGGATGCCTAAGGGCGCGGCCC CTGGAAGGTGTAACAGAAGTGGATCAAAGCAGAACAAGGCACAGACTTTGGAGGACACTATCTCATGATAGCCAGATTTGTTTCGAGAGAGTGATAG GGTACCATTTCCTAATTTCTGCACCTGGATCTTCCCACACCCATCATTTGGCCTCAAGGCCTCTTCCTTACCGTTCTGTTTCCACCTGCCTGCTCTG GGTACCATTTCCTAATTTCTGCACCTGGATCTTCCCACACCCATCATTTGGCCTCAAGGCCTCTTCCTTACCGTTCTGTTTCCACCTGCCTGCTCTG TGTGAGAACGTGTCTCTCTCTGTGGACTCCTCCCAGGACTCCTGGTCATTCCTCTCTGTCTGACACGGCCAACCACAGCCAGATAATTCCTCTTTGG CTGGGGCTTTCATCTCCTAACAGTGGATGTGGTGTCCTGGCGCTGTGAATAACTGATAATTGCCTGCACAATAAGCCAGTGTATGTTTCTTCCTGAAT CCTTTCTCTTTGACTGTGATCAAGCATGTGCCAGACTAACCGCTCCTGAGTAGCCCATAGGAACAAGAAGGCACTCACACCCCGAGCCTCAGGTTGA CCATAAGCAATGCAACTTTCCCTGAGACATAATCTCTACCGCCCCGTGTGCCCCAGCATCACTCCTGTGTTTTACAGTGTTCTGCTGAAAAGAAACA TAGCAGATACAGTTTAGAATAATCCAGAGCCAAGCCACGTTGCCAATGGGTGAAATGAGACAGTGCCATTTGCCTTTCACCTCTTGCTTCAGTTTTC GAAAAATTGTCCCCAGTGATTACAGAGTATTTGCATTTTTGTTGGCTTGGGAACGGGAATTGGCAGCATCAAGTGTTTCCTTGCTTAGAGCCACGTC ACTATTTACGTAGCAAACATTACAAGTCAGAGAACGGAGCATTACAGGGAAACTTCTTAGAATGCTCACAATCAAAGGAGACAAAAAGGGAACAGTT GGTTGTTTATAAACATGACGAAGGAAGAAAGGGACAATGTTGCTCTAGAGTCACAGACTTTGTGACTCCTTATTACATGATTGATGAAAATGACAAG TCTCATCTTCTATAGGATTGAATGTGGTTTTTTTTTCTACCATATGCATTGACTCCTGGTATTAAATGTGTTCCCAACAACTTCrCCTCAATGGCTG ATGATCTGGGGATGTTTGATACTGGAATTGTCTGAAGTCACAAAACACTTAGAGGATTTTTGCAATTTCAGTTAAGGTATATTCGGGACCTTATATA AAATAAATAGTTGTATTGTTGCCCACAAATACATCACTTTACTAATAATGTTCAGTTTAGCTCTTGGGATCCATGCCCAGCTTTTTCACATGGATGC TGAGAATTGAACTCAGGTCTTTATGCTTGCAGAGTAAGCACTCTTACCAACTAAGCCATCTCCCCATACCCCTGACTTTAACCCAAAGTGGAGCAA ATAGATGCATCCATGGGTAAGACAGGTTCACAAAAGCTTACTTCTTGGGCAAGTCACAGTGATGGCTAGTGGCCTCTCTGGATCTCTCTTCTTATGT GCACAATTGGACTAAAATGCGTTGCCCTGAACACCATACAGGTACATTTGAAGGGTGCATATCATTATGTCTGTGACAGTTCCCAAGGGCTAATGTA GGATATACGTAATCATAGTCTAAGTGGGTGAGCACTTGCGATGCACATAATTTTGTTGTCAGAGCACTGCAGAAAGCAGGGTCACCGCCACTCTTGA ACGTGGGAAAGTGAACTCACCACCCACGCCTTCACCCCTGTGAACTCTAGACACCTCCTCTCGTCCATGTATCATGAAGTGGTTGTCAGGGCTCACA GTGGGCGTTAGTCCATGCACCTGGAATCAAAGCATCAGAGGTTTTGTCTTCGTTTTAAATCAGAGGCAATGCATTAAAACAACAAAGTTTTTTTCTT TCCTGTTTTATTTTTTAATGTTTTATAAAATAATTTTTCCCAAAGATAGAATTTTACTTAAAAACAAAACAAAACAAAACAAAAACAAATGTAGTTC TCATTTTAAAAGAGTGAGGTCATCAGAAAATACATTTATCCAAAACAAGGTCTCCGTCTCTTGGAAGAGAGAGTACTGGGAATTGAACCCAGTGCCT TCCACACACAAGACAAGCATTCTACTGCCACGGTACACCCTAGGCTGAATAATGTCTTTCTGAGTATCTAACACTGACTGGCTCTATAAACCACTTG TTCTTACTTGTGAATGTATAATTTTAAAAGGTCAATTCTCAAAATACTGAGCTGCAGTCTAGCTTTTCTTACCGTCTTTTTATGGGAAGTATGAATG AAAAGTTTGCCCCATTCAGACCTCGATCACTGCTCAGTGGCTCCTTAGCCCAATAACATTAGTAATCTCCTCGGGGAGTATGGAGCTCTGCCTTTGG AAGAGGATGGGAAATTGCCTACTGGCAAAATTGTCCCCATTCTTTCAAGTCTGACTGTGATTTAAGAAGTTCTTAGTGGTCAGCTAGAAGGGCCCAC GACGGATGCTCAATTCACTAATTTCCTGTGACATTTTTCAAACAACAGTCCGCCATCTCACTGTGACATGTATCGATTTTCTTAAGTGTCAGTGCGA AAGAGGATGGGAAATTGCCTACTGGCAAAATTGTCCCCATTCTTTCAAGTCTGACTGTGATTTAAGAAGTTCTTAGTGGTCAGCTAGAAGGGCCCAC CTGGCCATTCCTTCCTCTCCACCAGCAACAATGGGAGCATGTGATTCACAAGGGAATCACATTCAACTAAAAAGAGAAACCGGGGTATGCTGTTTGC AAGGAACGGTTGAAAOTGGAACTCAATATGTCGTGTGGTGTGAAATAAATGTGTGTCTCACATGTTTTCCCATGCTGGGGGCAGGGGTAAGAAAGTA AAAGGCAGACTGGTTAAAGACATGGGGTGGGGAGGGCTGGAGGGACGAGTGGTAAGAAATGGCGACAGAGGAGATGAAGGTAATGTCATAATGAAAC CCATCACTGCTGTGTGCAACTAATAGATGCTAATAAAATAGGAAGTTTTAATGATTTAGGTAGCTTATTGCTTGCATTCACCTCACTGTTAAACTAT CACTTCTGGGGGATCCACACAACGAGCGAGCGAGTAAACCAGAAGATGGCGTTGAAGATTAGTAATCATATCTTTTAAACAAGATAACCATGTGAAG TCTCAAAAGGTTTCTTGTAATGACTCTTGTTTAAACTTCTGAACAGAGGATGTAGATTGGCTGAGGAAAATGTTGAAACCGCCTAAGTCAAGGTA GAAGACACGTGTGTCTAAGTGAAAAAAAGAAAAAAGAAAAAAGAAAAAAAAAAAAAACCAAAAACCTCGGGTTGGCTGCTTCTGTCCTTAGTCTGTGCACGCTT TGAAGAAATGTAATTCCTCAGCAGCAAGGCTGTGCTATCTGAAGCTACAATCTCTGCTTTGCTCCGAGGTGTGTCTCTGGTGACCGGGATAGTTCCC GACAGACAGAAGGTGTTCAAAGAATATTTTTGAATGAATGAAACCCCAAAGGAAGAAGAGGSGAAAATGGGTGTGACCAAAATTTTCTTTGAACGAA ACTCTGTTGTTTACTACCAGGGCTCTGACAATGGAAAACTAATTGGGGTGAAAGAACGACATGGCATCCTGTTAATTTCTGAGAAAGCCTGTTGATG TTAGGAAAAAAAAACATGCCGGTGGGCATCTCTGCACCAGTTTTCCTGTGGCCAAAATCAGATGTTTCTCCTAAAGTCCAGAACCCAGGATGGAAGA TTAAAAGAAAAACTGAGAAACATGTGAAATGAAAAAGTTGTCAAATCTTTACAAACGCTCCAAGTTGACCTGTGGTGGTGGTAATCTAAAATGATAC AGAAACTGGTAGTCTGCTTGCTTACCTGAAAACACCAAGATAACATATAAGCTCCAGGCATCCAAGCTGAGCTGGAGAAAGTCAGCGGCAAAAGCTC ATGGAGTTTACATATGAAGGTCAAAGAAAACACGAAAATAAAGTAAAACCTTCAGTCAGCCTAGCTGTTCTATTTGGGGCATTGGTACCTCACCGGC AACTGCCTCCCACGAGGCTGAGGTTAAAATTATCATTTTAAGGTGAATTGACATCCGGAAGCGCGCTAACTACCTGAGTACTCAGGGATCCCCCATC TCTTTTATGTTGCCATGATTGAAACTTTGGGGACTGTGCTTGTCTGAGTCATCTCAATTCGTCGGTTTCATTCACCCAACATGTATAAGCGTTTCAA ACACAGTATTTGGGCCACGGCTTATAAACTTGCCTTTCTATTTTTCTTTTTAGTCAGCGTGATATTCTCTAAACGCTCAGAGAGACAAGACTCCGCT TTGCCCAAGGATGCTCCCGACCTCTCTCAGTCTATCTCTTCTGTCACATGCTGTGAGAACCAAGTTCCCTGTGCTCCAGACTCTCCATCACTTCCCA ACCTGGCCATGAGCAGTTAGTAGTTATCAGCTATGCTCAGTGCAGATTCCAGTATCCCCTTTGCATGCCTCCACCTTCACAGGAACGGGCCATACCG ACTTGTCCCATCCGGTTGAGGATTTCTGAGTACATCAGAGTCCCCAGCCCCCTCCACAGGAGGAGCTGAAGAAAGCCAGGGTTTGTCTGAAGTGGGA CAGCCCTTGACCOGTGGGCTCTAGTCCGAAGCTCCTGTTCCTGCGGGACACCCAGGCACAAGGCAGAGGTGGGGGGCGGTCCTGGGTATGGGCAAG CCACGCCCTCTCAAGGCGGGGCCGAAGCGCCCGCCCTGCACTCCGCCTCCGGCTCTATAAAGTTCCTCTTTCTCACCTCACTTTCCTAGTTTCACCA CTTGAACTTGGGACCCTTTGCTGCCCTCAGCTAAGAGTGCGGGTGAGGTAAGGCCTGTAGTCGGGCAGAAGGAGGAGTGTGAGGCTGGTGGCAGAGG AAGCCTGGCTTCCATCTCTGAGCCTGAGGGAGAATGCTGAGATAGCGGACCCAGGCTCCGCTCATCTACGCTGCCCTAGGACCTGTGCACTTCGGGT TTTGTATGAAGCTGTTTGGGTGGGAGTTCCAGAACATCCCCCACGGGCTGGGCGGGACGAGCTAATGGGACTGTGGTGTCATCAAAGGATCGCACTG GCCACAGCTTGTCCTCAGAGGGACAGCCTCTGACTCTCTCTGCTCCAGTGGAAAGCTCCTTTCCAGCCCTGGTTCCTAAAGGACCCAAACTCATCTA GGGCTCCAGAGCGTGATTCCTAGGCCGGGCAGCCAAGAAGAGCTGAGAGCTCCAAACTTAGGGTGCTCAGAGCCCCTTTCCCCGCATGCCCCTTCTT CACTTCTCTGGCAAGAGTGCTAGTGTTGCTGTCCGCAGCACCCCTTATTCCCAGCCTCGGCTTCATTCCTGCCAGGGTTCACGCTGACATTCTGCAG GTTGGAATCTCCTGTTTCTTGGCTGCGCTGCTTGCCCCATAACCAGACTTCCCTTGTTGCTTCCAGGACCCACGTGATGGTCTCTGGTTGGGTAGG CCTGGGGTTATTCCGAGGACAAAGTAAGGGTGTCATAGAAGAAAGTCAAGAGAGTAAGCTAGGTACCGCAAACCTGCATGGCAGGGACACAGGACCT GGACAAGGGCTAGTCCATGTGCCAGGTCCTTTTCGCCTGGGGCAGCCAGGGCAACCTAAACCCAGGAAGGGGCAAGTGTAGAAACAGTGAGGGAAAA GTGGGATGAAAGCTACTTGGATCCAGCACAGAGGGACGAGTGAGCAAAGTGAGCGCCCCAGCGTGGCGCAAGACTTGGGATCTGCAGAGAAGCTGTG TAGCTAGGAGCTTTCAACGGAGCGTGTTAATGTAAATGTAAATGAAGAAATTACCTAATTTTTTTAATAATAAAAGAAAGAACAGACAGGCAAAAAA AGGAGGAGGAGGAGGAGGAGGAGGAGGATGGTGCGCGCCAAGGGATGCTCTCTATACCTTCGTCAAAGTACCTTCTCTTGGGGGACTTCGGAAGACT CTGGCACTGCACCCGAGCACCTTGGCAGCCTCAGAGACTCGGGGCCTCGTGGGCACTGCAAGAGTTTGGGACGGGGCTTCCTCCCGCCTCCAAAGTG ATGCGAAGGTAGTTGCAGGGAATGTGTGTCTCTCCTCAGCGCACAGCCCGAGGAGGTCCGCACGCGTCATGAACTTGGAGACGGGCAGCCGGGG CTCAGAGTTCGGCATGAGCGCAGTGAGCTGCGGCAATGGGAAACTCCGACACTGGTTGATCGACCAGATCGACAGCGGCAAGTACCCCGGGCTGGTG TGGGAGAACGAGGAGAAGAGCGTCTTCCGCATCCCGTGGAAACACGCGGGCAAGCAGGACTACAATCGTGAGGAGGACGCTGCCCTCTTCAAGGTTA GCAGCATTCAGGGATCCCTGGGCAGGGGTGGGGGTGGGGATGGGGAATCTGAAAGCTCTGAATGTCTGTGGCTCCCGGGCAAGGGACTAAGAGGTGG GCTCCTGCAAGGAGGAGGCCAGAGCATCAAGCATTGGACCCTGCTTAGGCAAAGTCCCCAGGAGAAGGGAAAGAGGTTGCAAACTCTCCGGGGATTG CATCACAAGAAACCAGGTCCCAATACTGTTTGTGTGGAGGAAAGAACTTCCAGCTTCAGGGGCATCTCTGGGGGACCGAGGTTCCGTTTGCATAGC CCATTCGCTGTTTCCTGCCACCACCACCGACTGCTAGGGCCACTCTCTGCTTCCCTGTCTCTCTGTGTTTTGTTATTTTTCTGAGTTTCTCTCTCTG GGTTTTGTTTCTTTGATTGGGCACCTCTACTGTCTGGTTCTAGTTCTAGAAGCTGCGATCTCTGATTTTCTTTCTTTGAGTAGCTTTGACTATTCCG AGTCTTTCTCTGGTATCCCCCTCCGACCCCGTGTGAGTCCCTTAGGACTGATGTCCCCAGAGAACTGGCTCACTGAACTGTGAAGCCCCCAGCCTCC ACCTGCCAGCAGGCCGAGGAAGGGGACTTCCTGCGGGAATTTGTTCAAAGTACCTCTGTGATTTTGTAGATGTCCTCTCTGGGGCCTGCCCCCTCCA CAGCTCTGTCCCCAGTCTTGCCCACATTGATTCAGGCGCTGGGCGTGTACAGCCCATACTAGGGGTCTCAGGACCCCACTAACATCATGTTCCACA TTTCAGGCAACAGCAAATTTGAAACAGTAACCTTCCTTGCTGAAATGCAATCCATAGAATTCTTTTGACGCTGGGCTTGACTTTTCTTCTCATCG TTCTTAGGCTTGGGCATTGTTTAAAGGCAAGTTCCGAGAAGGGATCGACAAGCCAGATCCTCCTACTTGGAAGACAAGATTACGATGTGCTCTGAAC AAGAGCAATGACTTTGAGGAATTGGTCGAGAGGAGCCAGCTGGATATCTCTGACCCATACAAGGTGTACAGGATTGTTCCAGAGGGAGCCAAAAAAG GTAAGGGGTTTTCCCAGCCCAGGTGGCAGGATAAAGGCATTATGGCACTCAGAGCCCTTCTTCCTAGAGACAGTCACGTCCTACCTCTGCTGTAG GTTAAGCCCAGATGTCCTTTTGCCCATGTCCTCTCTGTTATAAGTGACAACCCTGTGGTGTTAGTATAGGATGACCTGGCAGACTTTAAGCCCCATG GGTGTGTGGGTTATGCACTTGAAGGCATTATTTTCAGTTACTCCATTCAATTAGGATCTGGATCAAATTTCCAAACAAAATCTGGAAAATCCATTAA ATGTTTACTTACCTAATATCCTCTAGTAAGCATTTTCAAGAGGAGAAAGCACATCCCACACCCCATACATATTCACACTTCTTGTAATAAAACTGCT AGAGTTTCTGGTTTAACATGGCCTGCTAGGGTGGTTATGAATATTCAGATCTTGAGTTCCCTCTCTTCCAACTAGTCTACCTCAAGCAGTGCTCAGG AATCTGCATTTGGTTCCAACCATACAGGATGCCTTAACTAGGTACCATCTCACAACCAGAAACCACTTGGTGGATCACAGGGATCCTGGGTGGTGTT TCCTTCCCTGGCTGTCACTCACAAGTCAGCAAATGTTTAATCAGTTTAATGGCAAAGACAAATATCTCTCTAAGAAATTGCTTGAAAAACAAACAAA CAAACAAAACAAAACAAACCTAAAATACCCGATTGGTTAATAGGGCTATGCATTCTAAGAATTAAGTGCATAGGTACTTTTATAAGATTTAAGTCAG TTCCTTGTCTTACTCTGTGTTCTCTCTTCCTTTTCCCCAAACACACAGGAGCAAAGCAGCTCACTTTGGATGACACACAGATGGCCATGGGCCACCC CTACCCCATGACAGCACCTTATGGCTCTCTOCCAGCCCAGGTATGTGGTAGACTCTTGGTCTTGTGGAAGGCTGGCCCATGCCCTTTTGACTGGCTC CACACAGAGAGGCAAACACAAATGAAAAGTGTAGGGCTGACTTCTTATTTGCTATGGCTAGTACACACGCTGAACAAAAACTTGGTCAGAGAAGGAT GTTTCAGTTCCAGTGTGGTGTCACTGTCCCTGACGCCACAGTTTTGTTGGGGAGTTTGATGTGTCCCACCTGTGGAGAGAGGCTTCCACTGATGGTC AGATCTTCTGGGAATCAGACCTTTTGTGGAAGTCAAAGGTTTTGGAAGTAGTACTTTATCATGTGAAACCGCAGAGCAGCTGACTTCTCTAGGCGTC CCTGATGTGAATTACAGTACTGTTTTATTCACTTTGGTGGCTTAAAAAGGGCAGATTTCACTGCGGTATTCTTGGTGCCGTGTTCAGCCATATGATG AAGCCTTACAAAAATCACAGCTTTATACAATGTCCTCATTGTGCTTTCAGACCCTCTATGGCTGTTTTTTACCTAGTGTGATAGACAGTCCATGTCA CTTTTTGGGCAAAATGACTTGGCTGCTGGACAAAAAAAGGGGTTCCCTGAGGAGTTTGGGTGATATGAAATGACTCCGACACCCACTGATGTCTTCC TCTTAGCAATCCCTGTGCTCTGTCAGCAGGTTCATAACTACATGATGCCACCCCATGACAGGAGCTGGAGGGATTATGCCCCTGACCAGTCACACCC AGAAATCCCATATCAATGTCCTGTGACGTTTGGCCCACGAGGCCACCACTGGCAAGGCCCATCTTGTGAAAATGGTAAGGATTGTGCCAGGGCAGCA GACAGAAGAACAACCTGAGCTCGGGGTGTGGACAGCACCACAGGGCTTTTCCCTACCATTGAGATACCAGAGACACATCATATGAAGCTGCTACTGT TGTTGTTGTTGTTGTTGCTGCTGCTGCTGCTGGGGTGGTGGGGTGGTGGGGTGGTGGGGTGQTGGAGTGGTGGTGGTGGTGGTGGTTGTGGGGTGTT GGGGTATGTTGCCTTGTCCTGTGAAATGTTGAAGTCCTTAGATCCATGATAGGCCTCAGTCTGTGTGGGGACTTAACTAGAAGACCCCAGAGATCAT TCCAAGTAGCTGAAAAGTGCCCCATTTTTAATACATAGAGAAAAACATGGATGACAACAAATTCTCAATGACAGTAATGTCAATTATAAAACTCGTC TATATTTTGTTTTAACTGAGTTATCCCTTATTTCCGATGGTGATTAAGTTGGGGGGTTTGTTGTATCCCACCTATCTCCCTAGTCTGTATCTTTCTA CTCTCCTGTAAAGTAGAGAGTTGTACCCAGTCCACCTCAGCAGGAAATCATTGCTAGTTCATGTCTCTTGAATAATAATGAGTCATCTATAGCTGTT CTTGGTACTAAGGAAGGAAGGATCAGAGCGAAAGTAATCCACAAAGTGTCTCTACAAATGAGTGCCCTGCCCGAAAGACCCACAGGGGTCCCCCCAT GCTAGCTGGGCTCTCACAGAAGAAACGCCCACTAACCAGACACAAAAAAATTTCACAAACTATGTTCAGTGAGACTTGGGTCCTTTAGTGTTTATTT AGGTGAGTGCACCAAGCTCCACCTCGGGTCCTTTTTTGGCTGTGTATTTTAAGGTAGAGTCTTGCTAAATTACCAAGGCTAGGATCTTCCTGCCTTC AACTCTTGAGTAGCTGGGACTACAATCTTGTTCTAACGGGCTGAACATAAAACAAGTTTTTAGGACTTACAAGTTCACTGTTTAAATATAAGTCTTG ACATGGGTCGCCGTGCGAGTAGTTCTTTTATATTGTTCTGGCAATACTTTCCTTGTGACAATTTCATCAACACCCTCACTCAGTCTGTGCATGCTTA CACTAATCTTGCTTTAGTGTGACATAACTTCTCTGCTGCCAGAGAACACGGTTCAGCCCCTCCCCCTAGCTAACAAACAGTGAGCAGAATAAATGAG GGTTGAATAATTAATTCATCTTTGAACTAGTCTTATAGAAGTTTGAACTCTGACCCTGCTGGTAACTTGCTATGTGGGCTGGTGCAAGTCCCTCTCC TTCTGGGCCTCAGTTTCCCTATAGATTTGGAGTGAGCCCCAGGTTTCCATCCAGAGCTGTACTGTGGCTCCTTCCTTCATCACCCTAATTTTTATCA CTGGATGTGGACTTTGGACTTTGTCCCATAATCACACGTTATGCTGCTAGCAGGTGCTTAGAGGCTGTCAGGCTTGGGTTGGAGGCCATGGCCTCTC CCAACTCAAGAGCCTCCCCGCACTCAGACTCGATACTTAGACATCATCTGATTTTTATTTGCAAATGCAGGTTGCCAGGTGACAGGAACCTTTTATG CTTGTGCCCCACCTGAGTCCCAGGCTCCTGGAATCCCCATTGAGCCAAGCATAAGGTCTGCTGAAGCCTTGGCGCTCTCAGGTGAGTGTGGCGCTTC CTGTAAAGCTCCGAGGGAGGGGGCATCTCTCCTCTACTGAGGTTGGGTGAGGATTTAGACTCTCGCCTTGCAGGCCCCGGGGTCTGGAGTAGGCATG GTCCAGGCTATGTGGACATCACGCTGAGTCAAATACACTATTAGAAATCTCCACAGCAGTACCAGCTAGCCAAATACTATTTGGACGATGTCTTTAA CCTTCTACATCATTACCTGCCCAGTTTTCCAGGAATGTGTAACCAGGCTCCTCCTCCAGCCGACATTCTCCATTCTCGCAGTGTGGAAAGGCTTTAT AGGCACAAAAGAATGCTGTTTGTCCTTTTAGGGTGTAGGGTTGGCCACAAACAGGTGGTCTGAGTTGCTTCCAAGGAACACTGGTTCTGAACCCTGG TCTCTGAGAAGTTCTTATGCCCCCTAAAGGATCATATAGGTCTGACTCCCTCACAACTTTGACAGAATTGCTGAGCATGTGTGGATGTGATCTGATT TTAAAGTTCTGTTACTAAGGAAGCCTGCACTTGGAGATACTGACCAGCATTTTAAAAGCCCACACTCCGTGGAAGCAGACATCTTATGTCCATTTAG TCTTTAGATGATTTTTTTGGATGTTTTCAAATGGAATTATTAGAATTCTCATCATGCCCTCGGCTACCTTAAAAGCCTCTGACTGAAAACATCAACT GCATTTTGACAATTTTAGACACTTCCCTTGTTCTCGAGGGAGGAAGAAGTTTTAAAATCTAGTTCCTTCCAGCTCTGATGCTCAGGGAGACTTTGTG AGCCACTCAAGAACAGCCGAGGAGCACATCTGGGCATCAGGGTTTGTCACAGACACTAGAATGCTCTAGATCCTCTTCTGGAGCGCCAAAGACTTGT GTGGGTGCCCCAAGAGTAGGAAATAAACAGCTATTTATATCTCTGCAATCTTGTGATTTTGGTGACATTAAATGAAATGAAACCTGCCCTACCACTC ACCTCAGATGGCCAACGCCCCCTCTCTTTGGGTGCACCACTTGTGCTGTTCATAGCTGCAGCTATCGAAGAcAcCATGATGTGGGcTGTCAGAACTT GCCATTGAAGAATACGAGGCTTTTGTGGGTTTCTTCTTCTAGTTTGCATAATTAATTATCAACCCTGAGTGCACTTTTCAGAAAGCTATTCTTTCCA GGCATTGTTGGGGCTCCAACCACCAGCACGGGTATCTATCTCTGCCTGGGGAGCCCTTTGCACACCCAGCTTGCCCTTTCGGCCCGTGGGTGGTATT TTAAAGTGGCTTCTGAAATCAACAAAATCATGTGTCAATAAATTCCTGTCTTAAAGCTGTAGAAAACCTAGTTGTTGGGTTCTTTTCAGAGTTGAAC ACGAAGCTTAGAGGGATTTCAGGGGGTTTTACATTAACCACTGGCTTTTAGAGCAGTTCTCATCAATTTCTTCCCCTACTCCAAGAGAGCTGACTTA AAAATAAGAAAATAAAGGTATCATTTTCCAGAGCCCAGAAATTGTTATTTTAGTGCCTGTCTCTAACATATCTATGTGGGTTTTGTTGTTGTTTGGT TTTACTTAATGACATCATGGTAACACCTTAGGGAAGTTCCAGAGCTGAGGACACTATTTGCTTTTCTTCTAAGATGTTTCTGTATTTCTTTTACTAA TAGAAATCTGTCCCAGAGGTCAACTCCAAAATCAAAATTGAGTTGCTGGAAAACGAATTCCAATTCGGTAGTATTATTTCATATTGTAGACAAAATG CCACCACTGTTAACACCATCATCCGAAAAGCCCTCATAACAGGGGTGTGCTTTCTAATAAAATTTGGCTGAAAATTCAAGAAATATATACCTCTCCC CAAGAGAAGTAAATGGCCACAACAACATTTGAAAATGATCGTGTTAGAGAGATCAGTTTCTTTCCACAAGCTTCTCTTAGTATTCTGTGCTTGAGGT CTAAGAATCTACAGGGAATAAGAGCAGCTAACATCTCCAAGACTTCCTTGGTCCTAGGATCTTTCACTTGTTCGTGGAGCATCTTGACACTCAAGTG TTCCACCTGCTGTCCTTCGTATCAGTCTAGTCACCGAGTTTTTGGGGCTCTGAGCAAGGTGGCACCTTTTTCAAATCCATCAGCACTGACTCCAGAG TTTTGTTCACAGACTGCCGGCTGCATATCTGCCTGTATTACCGGGACATCCTCGTGAAAGAGCTGACCACGACGAGCCCTGAAGGCTGCCGGATCTC CCACGGACACACCTATGATGTTAGCAACCTGGACCAGGTCCTGTTTCCCTACCCGGACGACAATGGACAGAGGAAGAACATTGAGAAGTTGCTGAGC CACCTGGAGAGGGGACTGGTCCTCTGGATGGCTCCAGATGGGCTTTATGCCAAAAGACTCTGCCAGAGTAGGATCTACTGGGATGGGCCCCTGGCAC TGTGCAGCGATCGGCCCAACAAGCTAGAAAGAGACCAGACTTGCAAGCTCTTTGACACACAGCAGTTTCTATCAGGTAACACACCTCACAGTCTGTT AGAATGGAGGTGGTGGTGGGTGCTGGCTATAAAGGTCTCAAATGGCAGTGTCTGCCTACCCCAGACAGAGGTCTTCCTCCTGAGATCTGTGAGCTCA TGCAGAAATAGAATTCCTGCCTGATTCATGCCTAGCCTTTGTCTGTTGTGTACTCCCCTGATTAGCAGAGGGCCAGAAAGAGGATCCATATTTGCTG GCCAGGATAGACACTGGTGTGGGTTGATCTCTTAATTTATCATCATTCTTTTCACTCTAGGCTTTTGTTTTGTTTGTTTTGTCAGAATATATGTAGC TCAGGCTGGCCTAGAACTCCTGCCTCGGGATTTTATCTGTACACCAGCACATCTGGCCAATGAATTAAAATGTGGGCTTTCAGCGGCATGTGCCCCA CCCCCAGAGAGGTTTCACTGTGTTGGCTCTCTGCTCTCAGCAAGTTTATCTGCTGACACCTCAGCTCTTTAGGGGTTTCTAGAAAAATCAAGAAGGT TAGAAACACCATCTTAACATTTTTGGTTATGAGATGTGTCACCCTTATAAAATTGTCACACTTGCGAGGCAGGACCAAAGCTGAGAATGTAAGGAGC AGATTCAGCGAGGGGGAAATTCGGAGAAGAATTTGGTCTTATCTCTGGCATACGAAGGCTTCTAATCATATTTTCCAGAACCTGTACTTCTTATGGT ATGATTTTTGACTTTGGGTAGTTACGTTAGACCAGGGCTGGCTTATATGAAGTCATTAGTCTTGCCACTGGTGGGTACCACCCAGAGGCCTCCCCTA GAAACGTAGCCGAGGATGCCTTTAAGGAAGCAGGCTGCTCTGCTGACTGCTAATTGTCATTCCCTCACCCCATCATATCCTAAGCTTGCTTTCTTCC CAATGCCCTTCCCAAGCAGCTCAGCTCTGGCTTTCCTGTGCTTTCCTTTTCTTGAACCGGGACTTGCTCCTGCTCCATCTCATCCATGCACACTGT GATGCTTTAAAATGCGTGCACACTAGGATCTGGCTAAATCCACTAATTAGCATGCATATCACCTTGCCTGTCTATCTTTTTTTAATTTGGTAAGAAC ATTACTTGAAATCTACTCTCGATATTTTTTTAAGCACATGGTCCATTCATTATTAGTCATGAGGATTGGTCCTTGAGCTTGTGTTCAGCAAACTCCT CATGTCTTAGTGACAGTTTATATTCTTTGACCCACAGCTTCCTAGCCACTTCCCACGTGTGGTGACCGCCATTTGGCGCTACTTTTATGAGCTCAAC TATTTTGGAGTTCGCAATGCAATGGAGCGTCACGGTCTTTGTCTTTGTGTGCATGGGTAATTTCACTTGGCATGATGTTCTCCAGGCTCATTTGTGT CATTACTAATGACAGGCCTTCCCTCTTTATAAAGGCTAGGGATATTCCACTGGGGTATCTGTATCGTGTCACTTTCTCTTTATCTGTGTATCACTGT GGGTACTTGGGATGATGCCTTGTCTAAGCAGGTCTGACGGGTAACGCTGAGTGGGGGAGTATAGCTGTCTCTCCAAAACCAATTTGCTCTGCCTTGG TTACGTTAGACCAGGGCTGGCTTCTATGAAGTCATTAGCCTTGGGTCTGCACACAGAAGGGGACTGCTGAGTCCTCAATGTGCTGCTTCCTTCTGTT CATTTACAAAGAAGACGACAAGCCCTAGTGTGCTTGGTACTAGTGGTGTTTCCTCAGCCTTTTGAGCTCCAGTGGCCAATATTTGTTTAGGCTCATC CAAATCCTCTTTCGTTTCCAAAAACAAACATGCTCCTTGCTAAATATCCTCCOCTGAGAGGTGGGACACAGAAAAGAGAATCATCTCAGGCTCCAAG GTGTCTCAGGCTCCAAGGCGTCTCTGGCTCCAAGGACTGATGAAGATCCTTGGAGCTGGGTGTGATCTAAGCCTTGGTCAGACAGCCTTTGCCTCTC TTAGAGTGAGTTCTAGTGTTTGTGGTCCAAGGCAAAGAAAAATAACTTCTGGAGATGGATAGGTACACACATCCTATATCTGCCCTGGGGTCTGGAA GTCCTATGTGCCCTCCAGAAGGCTACCACTCACTCCCTGCTTGATTAAGGTAGCTCAGAATAGTGACAATTGCCAGCGACAGGGCTTTGAGGTACAC TAAGTCTTGGTGTGCCAAAGAGGATCCAATTTGGCAGGAAACAAATGCCAAAACAGAGCAGACACCTTGGACTAGAAATTTGCTTCCTAGGACTTAT TAGTTATTAATGAGTAAGGGCTATTTCCCTTTGTTCCCTTCTTCTCTAGTGGGGCCTGTTGTTTTTGCTGTCCACAGTCCCCAAGCCCCACAGAGGC TCAGGGAGATGACATTGCTGCAGAQAGGCCCAACAGCCTCAGAACCTAAGGATGCCCACCCAATGGTCCGGGAAGAGCAGGCTGAGGTGGGCTTTC TCAGAGAGTCGCATCCCTTGCTATTCTGACCTAGCCCCTCGTAGGTGTCTTCCCGGCCACAGTGCTATGCACTTTATACAGTGTGCCTAAACCCCTG GGTTTGATTTAAATTCTGGAAGAAGAAAGAGAAAGAAATGCAGGAAGTCAGTTCTGTGAGCTTCTAGAAGCAGTTCGGTTGCAGAGAGCAGTGGAAA TCTTTGATGTCTACCCATTCTGGATTTGCACCCCACTAGGGACAGTCCCCATAGGCACAGTTGAGAATTCATATCTGATCAGGGCAGAGTCTTCATG CCTGCTCTGTGGAGGCAGCTTTTTAATGTCAGTTCTTTGATGCAGACAAGACCTGGGAACCTAGCTCTGGGAGGAGGAATAAAGGTTAATGCCAGTG AGTGGATGTGGCTTTCTGCTTGTGCTGGGGGAGGAAGCCAAGGCCTTGCACATACAAGGCAAGTGCTCTGCTCCAAGTGGCGATGCCCCCAGCCATG GGCAGGTTTCTTTTCAGCAATCTTGTCTGTTTCATGTCTCTCAGGcAGGACTAGCCTCAGCATGACATCCTTGTCAGAGGGGCTTCATTGGTCCCCT TCTCCCTGTATCATCCTGTCCCCAAAGTGAGATTGAAGCCTACTCTGGTTCTCCAGTTTTGGAGTTTTAGACCTAGTGCCAAGTAGGACACAGCTGC CAACAGCTGGTGAGAGAAACAGATGCTCTTGGTGCCCAGACACCACGTGGCCTCCATGGTTAGCTAGTGAGGTTAAAAAAATAACCCTGGGCCATCA GAACATTGTGACTCTTTACATTAAAATGTCTCCTTGGCCTGTGCTGATTGCTTGACTCAGCATGGCTACTTTTCTTTTTCTTCTTTGTCTTCTTCTC TTTGACCTTGTGCATTTCTGTGAGTGTAGTGCTGCAGACCCAAGTTCTTAAGGTTGGGTCATGTTCCTTAAGAGTAATGAAGTAAAACCAGTGCCAA GTCAGGAGATCATATGTGAACTTGACCATGTGATTTTGTGTCTAGGGTCTGCTCTAAGGGCTGGACTTAGGGGAACAGAGCCCGGGCTCTCCCAAAG CAGACTTCCACGTGACTCTGGCTTTCCGTTCACCCGCTTTACCAGGTGTCTGAACAGTTTGGTTTTTTTTTTTCTTTCTTTCTTGTGGGTTTTCAGA GCTGCAAGTGTTTGCTCACCATGGCCGGCCAGCACCGAGATTCCAGGTGACTCTGTGCTTTGGTGAGGAGTTTCCAGACCCTCAGAGACAGAGGAAG CTCATCACAGCTCATGTGAGTACCTGGTTACATCACCCGTAAATCACACACTGTGGAGCTGTCCCTTTTAGAGAAGTGGCAAGTGACGAGTAAATGT CAGCTCACCTGGGAAAATAGATGTAGACCTTAAAATAGTGCAGGAGGAAGCAGGCTCCAGTGAACACCACAGCTCAGGGAGGCACCCGCAACCTACT TCCAGACAAATTCTGTCACCACCGAATCAGCAGGGCAGATGACTTGGACCCAAGGCTCTGTTTGTTCTGTATTCTTTATTGTTTCATACAGACAGTT ACCTGCCCTTTTATAGGAATTTTCAATAGTTGGGACCAAGTACTGCCCTTCGACATCTCTGTTTCTTGTGTGGTTTTAAAGATGCTGTCCTTTCGAG TAGAGTAGCACTTTCTCCCTGGGAGGCTGCCTGTTATGTATTATGCTTCATCGTGCCTCCTAACTTCAGATAGTTCCCAGACCCTCGTTTTGTTGCT GGACTTTAGGGAGTTATTTAACAGTTGGACAAGGGAGGTGGAGGAGGCTGAGTCTTCCCAGGAATCAGGTAGGTCGGTCTATCCTCACAGCTAGGGT TTATTCGGATAATGTTCATCACTCACTTAATAATTAAAAGGTAATTCTGAATACATGATGTTTTTTAATTAGAAAATTTTACTTAATTACATATCTT GAAAAGTATGCAGTGTGGAGTAAAGGTTGTGTCCCAGATAGCCACAATATCTCAGTGCAAATGGGATATTAGCTCTGATGATATCTCTTAGTGGAGA CTGAAGACTAGGCATACAGCGCAATGGAAGGCATTTGCTAGGCAGTGGTAAAGCCCTGGGTTCTAAACCCCGCCTAGGATGGGGGTTGGGCACTGAT GTTGAACATCCAGCCTCCCTTCTCGGTTGCAAAAAGTAAAATCTAAGAAGCAACAAACGGGCTGGAGAGATGGCTCAGTTGTTAAGAGCACAGGCTG TTCTTCCAGAGGTCCTGAGTTTAATTCCTAGAAACCACATGTGCCTTACAACCATCTGCAGTGAGCTCTAATGCCATCTTCTGGTGTGTTTGAAGAC TGCTACAGTGAACTCACATACATATAAATCTTAAAAAAATAAAAGGCAATGAAACTATGATCCTGGCCTTGAGCCTTTTCTCAGTTCTAACTGGTGG TTGATATCAAATGAGACTGCAGATGTGTGGATGAATCTAGCATAGATAAGCAGTATTTTTTTTTTTAAGGThGTGAGTAAATTCTAGCATAGATCTC ATTTTAAGGACTTTGGGTGCAGTGGGGCTCCGCAAAAAGGGAGCAACAATAGTCATATAGGCAAAGGGCCTCAAAATGCTGCCCCGTGGTCCACAGA TGGAAAACATACATGGTCACCCATGAACTCTGCTGGTCTCCTTATTACAGACTTAATTCATATGGGTGCTTACAGAGGAATCCTACCAGACATCACA TATCAAATAACAAAGAGGCTTGATTTATTGATGATTGGTTGTTACAGAGCACACAGCCTGACTTGGTGAGGCTGGCTTTGACTGGGGATGCAATCGA TGCTTATAAACAAACTAGGTCCATCAGAGCCAGCGAGCTGCTGTCTTGTGGCTGGCCAGCTCTGTCTTCTACTTGTGGTTCAGAGTTCTGTCTATTT CACAGTCATCTGGTTCTTCAGGATGAGCCCTTCTGTCAGACTCATGAGCCTCACTTACOCAGCATGTTACTTAGCCTTTTAATTTGGTCATCTCATT CAATAATGTCCAGTTAACTCATTCGCTAAATATCAAATCCAAGAGGTGATTGGTTTCAAAATGCCATATTTATCTTCTATTATAGAATCAAGAGTTC TTTTTCCAGGGTTTTTAATTCCAGGTATTATAAGAGCAAATGAAACTGGTTTTTCAAATGGCTCTGAATGTGAACTGCTTCACTGTGTTATGTTATC CTGTGCAGCTTGTAGGTTTTTACTTAGAGTCCTAGGGTCATTTCATGATGTCCCAATTGTATGGTGTTGAGAAGAATATTCTAGTGATGTCTTTTTT TCTTAAATGTCTTATTAAAGGTGGAACCTCTGCTAGCCAGACAACTGTATTACTTTGCTCAACAAAACACTGGACATTTCCTGAGGGGCTACGAGTT ACCTGAACACGTTACcACTCCAGATTACCACCGCTCCCTCCGTCATTCTTCCATCCAAGAGTGAGAAGAAATACTCTGACAGGGCAGCCGGCTGCTG CCCTTTCTCTTTGGAAGAGCTAAGAAGTGAGTGGGTTTCCACTTGAAGACAACAACAGGGCTTTGTGAGGAAAAACAGCTGTATCTGCTCAACAGAG GAGCTTCCCCCAGAAGAGTGCCTGTCATCCAGGTCTTGACAAGTGCCAGGACTTGGGTGACTGTGCCCTGGCTTATAACTGTGAAACTTGATCAGTG TTGTGTTTACATGTACTTGAATGCTGGCTTTAGCCTGGTATAGATGGACTTTTGCTTGAAGACTGAAAACCTGTGCCAGCATGAATCCCTGACAAGA GAAGACATACGTATTATTGGTCCATTTCTCAGGGAAGTAAAGTCTAGACTAGAGACTACGCTGTCCACTCACAGAGAAACGCATTCCTGGATAGAGG AGCTGTAGGTTGCCCAGATCATGTCCACTGAGTGAAGGGACTTGGTTCTTAGGTCCAGTCTAGGCTATCATGTCCTGATCCTGCACTCTCTCTGAGT AGACCCTACATCCTGTTTGCTCCCTCTTCTTGCCCTTCCCTAAAAGCCAGCTGGTGGTGGACTCTTGTTGCCACATACTTGAGCCAAAAACCATCAGGG ACATATAAGATGAGACATGTTTGCATCTCCTCTGATCTAACAACGGCTACAGTTTTTTGTTGTTGTTGTCTCCCCTTTCTGTTTTGCCTCTCATT CTTTAGAATTGTTGCTTTTTTGTAAAGAAAGGAAGAGAGAGAGACCGAATATACTAGAGATAGATTTTTAAAATTCTGTGCCATTTCCCCTTCTATT TGTTTTGTTGGCCATCAGTGGTCCCCATGGCAACACTGGAAGGGCGGAGCCTTTGAGCAGGTTGGGAACTGTCCCGGACACCAGTGGTTCAGTGTAC AGCTGTAGACTCAGTGAGCTGTTTCTGCTTATTTTGTATATTAGATGCTTCCTTGTGCCAATAATAGTTTGACAGAGTCTCAAAGCTACCGGGCTTC TTTTCCAACAACACATTCTTTCACAGAATCCCAAAGAGTCTCACTTGCCTTCACAACCGTCTGATCCTTTATTGTTACTGTTTTGTTTAGGTGGCTT TGCCATGCTCTGGGATTTTTCTCCTACCACAACATCATTCCTGACTCTTTCGGGCTCAGAAAGAGTTAAGCGCTCTTGCACACTTGGCACTTACTTC TTTTTAATTTTTTTTTTAACATGCCACTCTTAATAATATTTCTTCTTAAGTCTTTCAGCAGCATACATTCAATAAGCAATGGACCATTGGGTGTCTCATT TCATTGTTTTATTTTTAAAAAGGAACCTTGACAAATAATACACATTACAGAAAATGGAAGCATTTTTCATAGAGAAGGTAAGAACTGAAATGCATT TTATGTTCGAATCCTCCTTGCTAGTATTAGCCCCAAGAGTTCAGTCTGTCCTTTAAGCATGTTTTAGTTTTCAATACATATATATGAAGTTGCCCTT TCTTAGAGAGAGAGAGAGAGATATGTGATGACACTCTTATGTACCCAACTATACAGATTTACCTCATCTTTTGAGTGGCATGTGACTTCCACTGCT ATGTGCCTAGGTGCAGTTTAGACATCTTCTTAGCTACCCATCCCAGCAGCCCACTGAGTCTCGTGAACTAAAGTCACTTATACATCTTATAGATGCA AAACATTCTGGGGTATATTATCCCAAGGGAAGATGAAGGCAAAATCGGGAAGCACTCTTCCTGAGGCCCCAAGCCACAGCTGTCCTCCTGGAGTATC TTAACCATATCTGGCACTTCACCAAGGTCCCTTGCCTGGTCCTGTATGACCATGACTCTTCAGTCCATAAGCAGATGCTTTGTCTCAATTGCCATGT GAAGTCTTTTGGTTTTTGGTTTTTTTCCTTAATGTTAAGCTGTTTTAACAGTGAAGCTGAATTTTCTGGAAAATGCTGTATGGTTCGAGCCCCCAGT TCATGTTTCACTTTACAGCCATGCATGCTGATGCCTTCCATCTTGACAAATGGAATGATGGGTAAACACTCCTGACACAAAGAGGAACACCTTCCTC GTCCCTTGCTGAAACAAAGTGCAATGCACACAGTAGAATTTAGTTTGCTTGCACTGGAAGATGCCGTTGAAGAGGTAGGCTGAGGAACACTGTATCC TAGGGAGAAAATATGCAAGTCTCACGGGTGCTTTCTGTTGGCTTGTTTCTGGTCCTTGAGCAGGCTTAAGTATCTAGTTTCAAACTAGAAGCCCCAA AGCCCTCAGTCGTTGTCCTGGACAGAGTTGGTAGACCCCACCTGTAGAAATCCAGATGCACTCTGGGATTGGAGCACAGAGAGGCTTGCTCTATCGT GAGAATGCCCAGCCTGCAGAGGCCCAGGTGCGGTGCCTGAGTGGCTGTATGCCAGACACAGGAACGCCAGCAGGCTGAGTGTGGTGACTGATATGTG AGGTGCCCTTGCCCTGCAGACAGGCTGAATGTGAGCCCCAGCAGCAGAGGATTCTGAGAGTCAGGGTGGTGTCATQTCCTACACAGGAAGAGCCTTC AATATTACTTTTTAAACGAACTTTCCCCATTGCTGATATTTTGATAAAAACCCACACAAGGTTTAATTACATGCCCCCTCATCCCTCTCCACACAGT CTTGCCCATCCCACTGGTGAATTGTTGTTGTTTTTTGTTGTTGTTTTTTGTTATTGGTGAAAATTGTGAAATTGTTAAGGTCTCTGTTTTTGTTATTT ATCTCCCTAAATCACATGGCTGCTGCATACATTGCAATGTTGCCCTACCACATGTATGTTTTTGCAAGTTGCTTCTTCACTCATTGAAGAAGCCTGC ACCGTAAGTGAAACTCACTTAGTCCTTGCTAATTGCTGCTCACTGTCACGTGAACGCAGAGAAGGCTGATTTTCCTGGACCCATTTTCAGTGCTTTG AGGAACATGAGTCCAGAGTATATTGAAGTAGAAGACAGTGTTTGGCAAGCCAGTTCTTATTAGACACTGCTACAGGCTTCACAATCTTCAAGGTGGA CCCACCTCATGTGGAAGGGCATCATTGCCCCTCTGCTCCCATGCGCGCTGTGCACCCCCTTCACAGTGAAAGACCTGCTGGGGACCAGGACTCAGAGAT CTCTGGCTTCGAGCTCATATCTTGGCTTCCTGTCATGTCTAAGCCCGACAGGAAAGTGTGGCACCATCCTGCCTGCGGCGTTGGATGGATAGGCCAT GGATTTTGCTGTAAACTTGCTTCACAAGGAAAGCTGTGTGTTTTAAAATATTTGATAAATAAAGGATTTCTAGAAAGATTGACTGAGGAGCATATTT AATACCATCCTCACAGCCCTTGAAACACTTCCTCTATCTGCTGGGTTCTTGGTGAGGCTGTCAGTGGCCTACTTCCTTCCTGGCTGCCTGTGAGTCC CTGAAATCAGATCTCTAAAGTGTTCAGCAGAGAGAGAGAGAOAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGGGAGGTTCTAACTCATGGCTC TCACCATTCCTTCCAGCATACTTTTCTCAGATCACTATCCCCCACTGTTCTGGCTGTTTTGATCCTTAGTCCCAAAGGAGAGGAGGCAAAGCAAGAG AAAGTATGAAATCGTTTCTCAGTGGCACAGAGATGCCACTGAAAGGTGAAGTGCTTAGAAAGAAAGGATGTTCTATCATCATGAGAGAGAGCTGGCC AGGTGAGCAGGTGGGCAGAAGTCTTCCAGGGAAGAGCAGGGTACCTGTGTAGACATCNNNNNNNNNNNNNNNNNNNNCCTATGTTCTGAAAGGCCTG GTAGACTTGGTGTTTTTTTTTTTTTCTGTTTGTTGTGTTTTTTTTTCATTTTTAGAAAAAAAATTTAATATCTAGTGTGTGAGTTTACCTACTTGTA GGTACATGCACATGCAGTACTTGTAGGGCCAGGGAGGGGGGTCTGATCCCCTGTAACTGTAGGTACAGGTGGTTGTTAGCCACATACGCGAGAACCT GGAACTCCAGTCCTCTGGAAGAGCAACAAGGACTATTATCCAAGTTGAGCCATCTCTCCAATTAGGGAAAATATTTTTTAACTTGTTTTAATGGTTT GTTTTATACTTTGATTTCCTCTGAGTTTGTTGTCATGAGGGTAGCATATAGTGAGCCTGCACTCTGATAGGAGAGATTCCGGGGGAGAGGCACAGGG TGTCGGTAGACTCTTGGGTATCCCTAGGAGAACCTTGGCTGAAATTCCTCTCTGAGAAGCCAAGTCAGAGAATGCCGTTCTCAGCTGTATCACACAC ACTTCCTGACATGGCTGTGAACTTCCGTATCTCTTCCAGTGTCATAGGAAGACTGTCAGCCCAGGATAGGACTGTGGCCTGTGAAAAGCTCAGAGATTC AGAGATCTGAGAAAAGCATTTAGCAAGGATCTAAACAACATATTGAATTTACTAAATAAAAACCAATTGCTCTACTATTCCTACTTTGGGAGCTCTG TGTGTCCCATAAGTATACATGGGCTCAGGCCAGCATGCACAGCCAGGATTTCTCCAGAAAGTTCTACTACTTGAACCTAAGCTTGTTTGAAGAGATT TTGCTGACTTTTGAGTTCTTACATGATATTCCTATTCCCACAGGGCTTCTGGTCTTAGACTTTTCTTTCCAGTTACAACTTTGGTTGTTGGATTTGG TTTTCTATAGTTGGTAGTATTAAGACAAATACAGGGTTTTTCACATGGGCAACACTCATCCATCCCAGAAACAAACAAACAAACAAACAAACAAAAA CATGGCGTCTCCTACATGCCTTATTTCTGGGAAGGGACTGCAAGGTTGGTTGTAATATCTCATGTTTTCTAGCAGAAATGTCTTTTAATAAATGTCT AGTTAGGAATTATAGGGCACCCAAGGATGTTTCTTCTACAGCCTAAGCCAGGGGCCAGAGGATGTCTACACAGGTACCCTGCTCTTCCCTGGAAGAC TTCTGCCCACCTGCTCACCTGGCCAGCTCTCTCTCATGATGATAGAACATCCTTTCTTTCTAAGCACTTCACCTTTCAGTGGCATCTCTGTGCCACT GAGAAACGATTTCATACTTTCTCTTGCTTTGCCTCCTCTCCTTTGGGACTAAGGATCAAAACAGCCAGAACAGTGGGGGATAGTGATCTGAGAAAAG TATGCTGGAAGGAATGGTGAGAGCCATGAGTTAGAAAGAACCATAGCTGCAAGATGAGAGAACAACTCCATGGTTAACGGTGTGGATCAACACCTGA AAATGATGGAGATGCTGAGATGGGTCTGATCAGAGCTGACTGTGGGCCAGAACTTACACACACACACACACACACACACACACACACACACGTGCGA GAACCCCTCACACACACAGGATGGTGGGGCAGAGTTTAGGTACTAGAGCTCCTTCAAGGGTGCATCTTCAThATAATCTTCAATTATCTAACTTT TCTCACACTAGACCCCACCTATCAAAGGTTGTACTTAAGGTTGTATCACCTCCCAGTAGTGCTCATCAGCCACAAAAGCThTTAACATTGGTATTTA CTGTTTGTGTCTATGGCATATCACTGGTCATTCCTTTTTTATTTTTTTAACTTTTTATTGATTGTTTATGAATTTCACATCATGTACCTCAGTCCCA CTCATCTCCCATCTCTTCATATCCACCCTCCACCCTTGTCACCTACCCGCCTCCGAAAAAAAATTTTTGGAAGCTGCAGTGTGTCACAGTGTGTCCC ACAGTATACCCTTTTGTCCACACTTCCTTATATGCAAATGTTCATTGCAATGAGTCATTGGTCTGGTTCAAGGCCTCTGGCTTCTGTTACACTGTCA ATACTGGATCCTCACCAGGGCTCTTCTCATATAGAATCTCCTCCTGTTGTCCTATGTCATGGAGATCTTGAAGCTTTGGGCCTGTAGTACCCTCTCC TTCACATATACCAGCAGTTCATAGATGGCATAGAGCTAACTGAAAACCCTGGATCTGGGCCTGGGTGGTAGCTAAGTTGGTCAGCATGCCAGCTCTC CTGCACCCACACCACCAGGGCAAGCTCTCCAGGAGTACCCTGGCTAACTCACCCAATGCCACAGGCATCTAGAGCCAGAGCAAGCTTTCCAGCTCTG CCGTTGAAGCTCACCCACACCAACACCAGCAGAGCCAACTCTATTCTGCTGCTCAGGCAAGGGACAGGACTCACTTTCTTTAGTGTTATAGCTAGTG AGGAGCAGGGCCAGCTCTCCTGTTCTCATGGCCTGGTGGCCAGCTTCCCCTTCTACCTTAGGTGGAGAGGGGTAAGGTGGAAGAGGAGGGCATCTCC TTCTTGCTCATGCCACCCCACAGTAGACAAGTTGTGGGGCCAGCTCTCCCATGCTCATACCCACAGGGCTGGCTCACTTGCACCTCTGCTGCCAGGG TTGACTGTACCGTGCTGCCCTGGTGAGGTGCAGGGCCCACTTTTCCAAGTCCTACAGCCAGTAATTGTCAGGGAACAATGGCCATTCTAAGAAACAC ACATCACTGGCAAAGTCAACCACTGTGACATCAACAGGAThCAACCTAGAGTCGTTAGATAGAGGACCTCAGTTAAGGAAACGCCTCCATGATAC TGGCTTGAAAGCAAGTCTGTAGTGCATTTTCTTAATTAGTGATTGAAGTGGGGAGGGAGTTAAGGTCCTGGGGTCCTGGGTGCTATGGAAATCAGGC TAATCAAGCCATGGAGAGAACAAGGCAGTAAGCAGCACTCCTCCACAGCCTCTGCTTCAGTTCOTGTCTCCAGGTTCCTGCCTTGAGTTCCTGCCCT GACTTCCCTGGAAAATGAACTACAAGCTATAAGCTGATATAAAACCTGTCTTTCCCAAGTTGTTTTATCTGTCATGTTTTATCACAGCAATAGAAAC CCTAACTAAGACTTCATAAACTAAGAGTCAAGGATAGAAATCAATCTACTAAGCAAATGGAAGCTAAAACAAAACTGTTAGAACCATCTTCATACC TGATAAAGTTGAGTTGAAACCTTCAAACCAAAAATAGCCAGAAGATAAATCAGATCACTGTAACGTTACTGAAAGGACAATTCTTCAGGAGCAAA TAATAGAGACATCTACCACAATACTCTTAGATCTGATAAACATTTTTAGCAAAATAACTGTATACAAAAGCAACATGCAAAAACCAAAAAACAAAAAC GCCATAGCTTTTTAAACATATAAAAACAAGAGATGACCTAAGAAAGAAGAAAATAGGATAACTACACAAAAATACTAGGGCTCATGTTCATTAAGAA ACCTTAAAATGCACAAAAAACCGATCCAGGTACAACAATAGTGGAAGATGTCAATAATTCCCACTCAAATCTTTTTTGTTTGGTTTGGTTTGGTTTG GTTTTGCCAGATAGGGTTTCACCATGAAGTCTTGCCGGACTATAACTTGCTATTCGATCAGACTGGCCTCAAACTCACAAAGGTCCACAGGTTAGGG TTAGGGTTAAGTTCTCCTGCCTCTGCCTCTGGATGCTGAGATTAAAGACTGTGACACCATGTCTAGTCTCATCCTTAGATAGGTCTCTGGGATGGTC AGCTTTAATTGCCAACCTAATAAAGTCTAGGGTCAACATGACCTGAGAGGAGAGTCCAGATGAGTGACTGTCAACATGGAGTGTCAACAACTTTGGG CAAGCCTGTAGAGAATATCTTATGTAAGTTAATTGATGTAGGAAGACCCAGCCCACTGTAAGTGGTACCATCCCCTTGGCAGGGTTCCTGATCTGTT TAAGAGTGGGAAAATGAGCTGAGAACCAGCAGGTATGTGTGCATTCATTTTTCTCTCCCCTCAACTGTAGTTTTAATTTGACTTGCTGTTTGAGTTG TTGTCTTGGCTCTCCCAAAATGATGGACTGCAACCTAGAATTTTAAGCTGAAATACAAACCCTTTTCTCTCTAAGTGGTTGTGTGTGAGAGAGGGAG AGAGACAGAGACGGAGGCACACACACACTCAGAGAGGGGGGAGAGAGGGAGAGGGGGGGAGGGAGAGAGGGAGAAAGAGGGGTATTTTTTAAAATTA CAGGAACAAAAATGAAACTAGGAGTTTCCAAACTAAAAGTAAGCAAAAAACTTCACAATTAAAACATGTCAGGTATCAACTGGACTTAAGAGGTAT CAAACAGACTGGTCCATCTAAAAGATACAAAGTATACATTATTCTCCTTTAGCCATAGAATCTTTTTTAAAACTAACCTGAATCTGTTGCCTACCTG TGGATCCTGTTCTCCTAACTGAGCTGCCTTGTCTTGCCTCAGTGGGAGAGGATGTGCAGTAACTTGATGTGCCAGGGTGGGGTGATATCCAGAGCGG CTCTCCCTATTCAGAGGAGGAATAGGGAAGGGGCTATGTGAGGAGGGGCCTGGGAGGAAGGGAGGCTGTGGTCAGAATGTAAAGTGAATGAATAAAT TAATTAATGAAAAATAAAACAAAACAAGACAACGCACATTATAAACCACAAAACAATCCTTATCCATCAAAGGAACATTTGAAAACGCTTGCACTGC ATTATACCATAGTAGAATAAAACTAAAATTAAAAAGTAACAGCAACAAAACCAACACACATTCTAGGAAAGTGAGCAATGAGTCATTGAAGAAGCAA GGGAAGAAAAATTTCAATCCCTAGAGTCAGATGAAAAGAACTGCTCAACTTACTAGAACTTCTGTGGCACATCTAAGGCATTCTGCAAGGAAGGTG ATGGTCATATGTGTTTATATTAGCAAAAAGTATCAGGTAGACCTCAAATACATAATTAAATAATGGGGGGGGGGAGAGGGAGAGAGAGAGAGAGACC AAATTTGTATGCAGAAGATTGCAAGAAAAATAAAGAGAAGGTCAGAGATCAATTAAATGGAGACTAAGAGAGCAATGCATACAGCCAGTCAGAGAGT TGGTATTTGAAGAGATAAACAAGTTTGATAATCCTTGCAGAGCAAAAAGGAGAAAACTCTCAGATGAAGAAGTAAGAACAAAGCATGGGATCACTA GGGAATACTTTGAAAATTAATTTCAAAACCTCAGAAGTCCAGAGGAAATGGATACATTTCTAAACACATATGGTCTGCTAGAGTTAAATCAGGAAAA TACAAGCAGCATAACTGGACTCAAAATAACCAAAATAACAACCAGTTGTTGAAGCAGTAACTAAAAATCTCCACACAAAGAAAAGTCTCAAACTAGA TAGATTCACTGCTTAATTCTACCAACCTCTTAATGAAGATTTAACAGAATACTCTTAAATAGATTCACCAAATAAAAAGAGAAGGAACAAGACCAAA GTCATTACACAAAGCCAATAAAATCCTGATTCCAGAGCCAACGAAGGATACAACAACAAAAACTGAAAACTGTAGACCAACTTCCTTTAAGAATTCA CAAGCTCTTTAAGCGCTCACCTTTCTTACTCTCTAGCTCTCCTTCTCTCTCTCCCTTCTCCCCCTCTCTCCACATGGCCTCTCTCTACCTTCTCTCC TTCCCCCCGCCTTTCTACAATAAAGCTCTAAAACAAAACAAAAAAAAAGCATTCACAACAAAATACTTGCAAACCAAATTCAGAATCCAATAGACAA TGCATCTTAATCGAGTTACTTTCATCTCAGGAAAGCATGATTAGTCTAACATATGCAAATCAATACATGTATAAGGACAGAAATCAGAAGATTATCT CAAGAGATGCAGAAAAGGCATTTGAAAATTCTCAATATCACTAGACATCCCGAAGAAACTAGGAATAGAAGAAACATTATAAAGACCTTGTAAAAGC TTACAGCTGACTAAATGGGGAAAATCCAAGAGGATTTCTTCTAAACTCTAGAACAAGACAAGGTCCTCACTGTGTCTATTATTATTCAATATACTGC TTAAAGTCTTAGCTAGAGCGACAAAGGAGGTGGAAAAATAATGGGAATATAAATAAGGAAGAAGTCGAGGTATCCTTATTTGCATATAGAGCTATCC CTATTTGGAGACAGCATGCATACATTTAAACTCTACTCAAGACTCCACCAAAAACCTCTTAGATATGATTAAATAGTTTCTGCAAAGTAACAGGATA CAAAACCATACAAAATCAGTAGCTTTTCTATGTAGAAATATGAAACCACCTAAGAAAGATAAGTTAAAAAAAAAAACTATTCACAAGAGCTTCAAAA AGAGTTAGATGTGAACCTAATAAAGAATATGGATGCCTCTAAAGTAAGGCCTTTAAGACACTGAAGAAAGAAATTAAAATTGATATTAGAAGATGCA AATGTCTTCCATGCTTATGGAATGGCATAAGCTAATATTGCAAAACTAACTGGACCACTGAAAGGGAATATAGTTTAATTCAGTGTCCAACAAAAGT CTAATGTTTTTGACAGAAATTCTAAAGTTCGTATTGAATCATGAAAGTCATTAAAAAGCTAAAGCAGTCCTGAGAAGAAAACAATGGTGAAGGGATC GAACTATCTGACTTCAAATTGTACCACAGCACCACAGTGACAAAGACGTTGGTACTGAACAGATTAAACCAACAGACTGGATTAGAGTAACCAGAAA TTAGAGCCCACACAACTGTAGCCAAATAGTTTTTGATAAAGGGGTCAAAAACATACATATATACGTTAGAAAAAAACATAGCTTCTTTAAATAATAC TAGGAGACCCAGATACCCACATGTCAAAGAATGGAATCGGATTAGTGTGTATCGTACTGCACAAAAATAAATTTGTAATTGATCAAAATCCTTAATA TAAGGTCTGAAACACTGAAACTTCTAGAGGTAATTCACTCAAGACAGAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTAAAAC TGTCCCCAGACTCAGAAAACAATCACCAACAAAGCCTGGCAAGGACAGGGGTGGAGCAGGGGCTGACTCCTTGTCAGTGTTAGGGCAAGTGTGAACC CATATGGCCTCTATGGAGATCAGTATGGAGGTTTCTCAAAAACACTAAAAATAGAACTACCAATGACCCAGTCTTTTAAATCCTGGAATAGACCAAA GGATCCTAAGTGCAATCAAGAGATGTTTGCCCATCCATGTTTATTGCCGACCTATTCACAAAGGGATACCCTGAGTGAGACAAAGAGGAGACTCAAA GGAATAAAGAAGAGGTAACTACATGGTAGACATAGAAAAGATTTAATGGGTTGAACAAGTTATGAGTGGTCAGGGAATGGGCCAAAGTTCATGGACA AGGCATTAATAATAAACAATTAGTCTCAGAGGTGTCTTTCTGAGAGCTGGGACTAGOAAGGAAAACCAGATTTTTTTTTTTTAACAAGGAGAATCTC AGAGCTCCCTTCTCTACAGGTCTAATCTCAGAGATTTGTCCTAGGGATGGACCACAGCGGTGGCTGCCTACATCTGCCTAGGTCTCATTGGCCCTCC ATCCTTATTCCCTGCGTTTTATGTAACACTGTGACCAAGGAGATGTCCACACACTCATTAAAGACTTCACATAGAAACAAGGATCAGAGTTGAGTGG CCCAACTTTGOAGACCTGGGGAAGGTTTTAGAGCTCAAGTCTTTAGTCCAAGAGAATGGATGGATAGACGCATGCTGACTAAGGAGGAGATAGATGG CTACCCTTTTGTTCTTACATTGTTCCTGAGATTCGCAGAATGGCATCTCACCCCAGAGGTAACTGAGTCCAACAGGCAGGGAGCCCCCATCATTTGA TATTTTCCAGATTTGCTGTATGCCACCAAGAGAGCACACATAGTGAGAAAGGACCGTGTAGCCCAGGGCACCGGCTWTGGAAAGTGCGTGATGGGAA TGGATOGAAAACATTGCTGTGGGTGAACTTTGTTGTTCCGGGTCTTTATTCTGGTGATGCTGTTGTCTTTGTTCAGACATCTTAAACTCAGTTGTTA TGTCAGTATTAGTAATTCCAATTTCTTCTTTAATTTCCATGCAAGATAGGGCTTGCCTGTAAAGTGOACTGACAGAGGCAGCGTTCTATATTTAGTG AGGCAGATGCTATCTGCAAATTACAGGGAAATGATTGCATCAAGGTCCCTGGTTGGTGAAATAAACOACAATAAAGAAATGAGGAGOCAGAGAGGGG CAATGTTCTAGAAGTCACTAAGAACCAAAGTTGCTTGACTCTGACTGGTAATGATTTCTTGGTCCCCAAATGCCCTCCCATGCCCAAGCAGCATGGC CTTCATGCCCTTGGGGTTAGAGGAAGAATAATCACATTGAACTAITTCCTCTACACCCTGAGAAAATGATTATCATCTTCACCGGACAGTTAAGTGC CTAAACCTCAAACCACCAGGGCAACTGTGTGATTTTAGGAAGGACGAGAAACAGGGCATCTATTTTGTGACTTACCTAAACCCAGGAGCTATCAGAG GGCTTCCTGACACTTTTAAAAGAAAAGAAAGCGTAACTACAAGGCAAGCATAGGGCCTTCCTGGGCCATGATGGAGCCGAGGGTTCAAGTTTGTAGT GACCGTGCCATTTTCTTCCCATCCTGAATACAGAATTCACTCTGGGATTTTCATCATAGACAAACACAATTCAGGTCACCAGAGTAAACTGCTTCTG TAATGGTAAATTTCCCAGCAGGTCTTAAAATAAATAGATAAATAAATAAATAAACAAACAAACPLAACAAATACACACATACATACATAACATACACA CATACATACACATATATTTTATAATAGTCTGTGCAACCTAATGTTATTTTTCAGCTCACATTTATTTAATTATTAGGAATCCAGGTTACCTTAATTT TTTTGTGCTTGCTACACACTTTCATGCATACCAGGT MOUSE SEQUENCE-mRNA GGGACCCTTTGCTGCCCTCAGCTAAGAGTGCGGGTGAGCGCACAAGCCCAGGAGGAGGTCCGCACGCGTCATGAACTTGGAGACGGGCAGCCGGGGC TCAGAGTTCGGCATGAGCGCAGTGAGCTGCGGCAATGGGAAACTCCGACAGTGGTTGATCGACCAGATCGACAGCGGCAAGTACCCCGGGCTGGTGT GGGAGAACGAGGAGAAGAGCGTCTTCCGCATCCCGTGGAAACACGCGGGCAAGCAGGACTACAATCGTGAGGAGGACGCTGCCCTCTTCAAGGCTTG GGCATTGTTTAAAGGCAAGTTCCGAGAAGGGATCGACAAGCCAGATCCTCCTACTTGGAAGACAAGATTACGATGTGCTCTGAACAAGAGCAATGAC TTTGAGGAATTGGTCGAGAGGAGCCAGCTGGATATCTCTGACCCATACAAGGTGTACAGGATTGTTCCAGAGGGAGCCAAAAAAGGAGCAAAGCAGC TCACTTTGOATGACACACAGATGGCCATOGGCCACCCCTACCCCATGACAGCACCTTATGGCTCTCTGCCAQCCCAGCAGGTTCATAACTACATGAT GCCACCCCATGACAGGAGOTGGAGGGATTATGCCCCTGACCAGTCACACCCAGAAATCCCATATCAATGTCCTGTGACGTTTGGCCCACGAGGCCAC CACTGGCAAGGCCCATCTTGTGAAAATGGTTGCCAGGTGACAGGAACCTTTTATGCTTGTGCCCCACCTGAGTCCCAGGCTCCTGGAATCCCCATTG AGCCAAGCATAAGGTCTGCTGAAGCCTTGGCGCTCTCAGACTGCCGGCTGCATATCTGCCTGTATTACCGGGACATCCTCGTGAAAGAGCTGACCAC GACGAGCCCTGAAGGCTGCCGGATCTCCCACGGACACACCTATGATGTTAGCAACCTGGACCAGGTCCTGTTTCCCTACCCGGACGACAATGGACAG AGGAAGAACATTGAGAAGTTGCTGAGCCACCTGGAGAGGGGACTGGTCCTCTGGATGGCTCCAGATGGGCTTTATGCCAAAAGACTCTGCCAGAGTA GGATCTACTGGGATGGGCCCCTGGCACTGTGCAGCGATCGGCCCAACAAGCTAGAAAGAGACCAGACTTGCAAGCTCTTTGACACACAGCAGTTTCT ATCAGAGCTGCAAGTGTTTGCTCACCATGGCCGOCCAGCACCGAGATTCCAGGTGACTCTGTGCTUEGGTGAGGAGTTTCCAGACCCTCAGAGACAG AGGAAGCTCATCACAGCTCATGTGGAACCTCTGCTAGCCAGACAACTGTATTACTTTGCTCAACAAAACACTGGACATTTCCTGAGSGGCTACGAGT TACCTGAACACGTTACCACTCCAGATTACCACCGCTCCCTCCGTCATTCTTCCATCCAAGAGTGAGAAGAAATACTCTGACAGGGCAGCCGGCTGCT GCCCTTTCTCTTTGGAAGAGCTAAGAAGTGAGTGGGTTTCCACTTGAAGACAACAACAGGGCTTTGTGAGGAAAAACAGCTGTATCTGCTCAACAGA GGAGCTTCCCCCAGAAGAGTGCCTGTCATCCAGGTCTTGACAAGTGCCAGGACTTGGGTGACTGTGCCCTGGCTTATAACTGTGAAACTTGATCAGT GTTGTGTTTACATGTACTTGAATGCTGGCTTTAGCCTGGTATAGATGGACTTTTGCTTGAAGACTGAAAACCTGTGCCAGCATGAATCCCTGACAAG AGAAGACATACGTATTATTGGTCCATTTCTCAGGGAAGTAAAGTCTAGACTAGAGACTACGCTGTCCACTCACAGAGAAACGCATTCCTGGATAGAG GAGCTGTAGGTTGCCCAGATCATGTCCACTGAGTGAAGGGACTTGGTTCTTAGGTCCAGTCTAGGCTATCATGTCCTGATCCTGCACTCTCTGAG TAGACCCTACATCCTGTTTGCTCCCTCTTCTTGCCCTTCCCTAAAAGCCAGCTGGTGGACTCTTGTTGCCACATACTTGAGCCAAAAAACCATCAGG GACATATAAGATGAGACATGTTTGCATCTCCTCTGATCTAACAACGGCTACAAAGTTTTTTGTTGTTGTTGTCTCCCCTTTCTGTTTTGCCTCTCAT TCTTTAGAATTGTTGCTTTTTTGTAAAGAAGGAAGAGAGAGAGACCGAATATACTAGAGATAGATTTTTAAAATTCTGTGCCATTTCCCCTTCTAT TTGTTTTGTTGGCCATCAGTGGTCCCCATGGCAACACTGGAAGGGCGGAGCCTTGAGCAGGTTGGGAACTGTCCCGGACACCAGTGGTTCAGTGTA CAGCTGTAGACTCAGTGAGCTGTTTCTGCTTATTTTGTATATTAGATGCTTCCTTGTGCCAATAATAGTTTGACAGAGTCTCAAAGCTACCGGGCTT CTTTTCCAACAACACATTCTTTCACAGAATCCCAAAGAGTCTCACTTGCCTTCACAACCGTCTGATCCTTTATTGTTACTGTTTTGTTTAGGTGGCT TTGCCATGCTCTGGGATTTTTCTCCTACCACAACATCATTCCTGACTCTTTCGGGCTCAGAAAGAGTTAAGCGCTCTTGCACACTTGGCACTTACTT CTTTTTATTTTTTTTTTACATGCCACTCTTAATATTTCTTCTTAAGTCTTTCAGCAGCATACATTCAATAAGCAATGGACCATTGGGTGTCTCAT TTCATTGTTTTATTTTTAAAAAGGAACCTTTGACAAATAATACACATTACAGAAAATGGAAGCATTTTTCATAGAGAAGGTAAGAACTGAAATGCAT TTTATGTTCGAATCCTCCTTGCTAGTATTAGCCCCAAGAGTTCAGTCTGTCCTTTTAGCATGTTTTAGTTTTCAATACATATATATGAAGTTGCCCT TTCTTAGAGAGAGAGAGAGAGATATGTGATGACACTCTTATGTACCCAACTATACAGATTTACCTCATCTTTTGAGTGGCATGTGGACTTCCACTGC TATGTGCCTAGGTGCAGTTTAGACATCTTCTTAGCTACCCATCCCAGCAGCCCACTGAGTCTCGTGAACTAAAGTCACTTATACATCTTATAGATGC AAAACATTCTGGGGTATATTATCCCAAGGGAAGATGAAGGCAAAATCGGGAAGCACTCTTCCTGAGGCCCCAAGCCACAGCTGTCCTCCTGGAGTAT CTTAACCATATCTGGCACTTCACCAAGGTCCCTTGCCTGGTCCTGTATGACCATGACTCTTCAGTCCATAAGCAGATGCTTTGTCTCAATTGCCATG TGAAGTCTTTTGGTTTTTGGTTTTTTTCCTTAATGTTAAGCTGTTTTAACAGTGAAGCTGAATTTTCTGGAAAATGCTGTATGGTTCGAGCCCCCAG TTCATGTTTCACTTTACAGCCATGCATGCTGATGCCTTCCATCTTGACAAATGGAATGATGGGTAAACACTCCTGACACAAAGAGGAACACCTTCCT CGTCCCTTGCTGAAACAAAGTGCAATGCACACAGTAGAATTTAGTTTGCTTGCACTGGAAGATGCCGTTGAAGAGGTAGGCTGAGGAACACTGTATC CTAGGGAGAAAATATGCAAGTCTCACGGGTGCTTTCTGTTGGCTTGTTTCTGGTCCTTGAGCAGGCTTAAGTATCTAGTTTCAAACTAGAAGCCCCA AAGCCCTCAGTCGTTGTCCTGGACAGAGTTGGTAGACCCCACCTGTAGAAATCCAGATGCACTCTGGGATTGGAGCACAGAGAGGCTTGCTCTATCG TGAGAATGCCCAGCCTGCAGAGGCCCAGGTGCGGTGCCTGAGTGGCTGTATGCCAGACACAGGAACGCCAGCAGGCTGAGTGTGGTGACTGATATGT GAGGTGCCCTTGCCCTGCAGACAGGCTGAATGTGAGCCCCAGCAGCAGAGGATTCTGAGAGTCAGGGTGGTGTCATTTCCTACACAGGAAGAGCCTT CAATATTACTTTTTAAACGAACTTTCCCATTGCTGATATTTTGATAAAAACCCACACAAGGTTTAATTACATGCCCCCTCATCCCTCTCCACACAGT CTTGCCCATCCCACTGGTGAATTGTTGTTGTTCTTGTTGTTGTTTTTTGTTATTGGTGAAAATTGTGAAATTGTTAAGGTCTCTGTTTTTGTTATTT ATCTCCCTAAATCACATGGCTGCTGCATACATTGCAATGTTGCCCTACCACATGTATGTTTTTGCAAGTTGCTTCTTCACTCATTGAAGAAGCCTGC ACCGTAAGTGAACTACTTAGTCCTTGCTAATTGCTGCTCACTGTCACGTGACGCAGAGAAGGCTGATTTTCCTGGACCCATTTTCAGTGCTTTG AGGAACATGAGTCCAGAGTATATTGAAGTAGAAGACAGTGTTTGGCAAGCCAGTTCTTATTAGACACTGCTACAGGCTTCACAATCTTCAAGGTGGA CCCACCTCATGTGGAAGGGCATCATTGCCCCTCTGCTCCCATGCGCTGTGCACCCCCTTCACAGTGAAAGACCTGCTGGGGACCAGGACTCAGAGAT CTCTGGCTTCGAGCTCATATCTTGGCTTCCTGTCATGTCTAAGCCCGACAGGAAAGTGTGGCACCATCCTGCCTGCGGCGTTGGATGGATAGGCCAT GGATTTTGCTGTAAACTTGCTTCACAA MOUSE SEQUENCE-CODING ATGAACTTGGAGACGGGCAGCCGGGGCTCAGAGTTCGGCATGAGCGCAGTGAGCTGCGGCAATGGGAAACTCCGACAGTGGTTGATCGACCAGATCG ACAGCGGCAAGTACCCCGGGCTGGTGTGGGAGAACGAGGAGAAGAGCGTCTTCCGCATCCCGTGGAAACACOCGGOCAAGCAGGACTACAATCGTGA GGAGGACGCTGCCCTCTCAAGGCTTGGGCATTGTTTAAAGGCAAGTTCCGAGAAGGGATCGACAAGCCAGATCCTCCTACTTGGAAGACAAGATTA CGATGTGCTCTGAACAAGAGCAATGACTTTGAGGAATTGGTCGAGAGGAGCCAGCTGGATATCTCTGACCCATACAAGGTGTACAGGATTGTTCCAG AGGGAGCCAAAAAAGGAGCAAAGCAGCTCACTTTGGATGACACACAGATGGCCATGGGCCACCCCTACCCCATGACAGCACCTTATGGCTCTCTGCC AGCCCAGCAGGTTCATAACTACATGATGCCACCCCATGACAGGAGCTGGAGGGATTATGCCCCTGACCAGTCACACCCAGAAATCCCATATCAATGT CCTGTGACGTTTGGCCCACGAGGCCACCACTGGCAAGGCCCATCTTGTGAAAATGGTTGCCAGGTGACAGGAACCTTTTATGCTTGTGCCCCACCTG AGTCCCAGCTCCTGGAATCCCCATTGAGCCAAGCATAAGGTCTGCTGAAGCCTTGGCGCTCTCAGACTGCCGGCTGCATATCTGCCTGTATTACCG GGACATCCTCGTGAAAGAGCTGACCACGACGAGCCCTGAAGGCTGCCGGATCTCCCACGGACACACCTATGATGTTAGCAACCTGGACCAGGTCCTG TTTCCCTACCCGGACGACAATGGACAGAGGAAGAACATTGAGAAGTTGCTGAGCCACCTGGAGAGGGGACTGGTCCTCTGGATGGCTCCAGATGGGC TTTATGCCAAAAGACTCTGCCAGAGTAGGATCTACTGGGATGGGCCCCTGGCACTGTGCAGCGATCGGCCCAACAAGCTAGAAAGAGACCAGACTTG CAAGCTCTTTGACACACAGCAGTTTCTATCAGAGCTGCAAGTGTTTGCTCACCATGGCCGGCCAGCACCGAGATTCCAGGTGACTCTGTGCTTTGGT GAGGAGTTTCCAGACCCTCAGAGACAGAGGAAGCTCATCACAGCTCATGTGGAACOTCTGCTAGCCAGACAACTGTATTACTTTGCTCAACAAAACA CTGGACATTTCCTGAGGGGCTACGAGTTACCTGAACACGTTACCACTCCAGATTACCACCGCTCCCTCCGTCATTCTTCCATCCAAGAGTGA HUMAN SEQUENCE-GENOMIC TCCTGAGATCTTATCTTTGATATAAGTTAGCTCCATTTACACTTAGCAGATAATACCAAATTAAAACAGAGACTGAATTCAGTGAGCAGAGAAAACA GCCTAGCCCATGGATTTGTTCTCAATGCACTGCCTCCTGGCTTTGGTGATTTTGCAAAGAACTGAAAGAAAAAGCACAACATTCAGAATAGAAAGGG ATTTCTGAAGGGAGTTTATAACTGAAATTTCAGTTTGAACTGGATGAGGGACGCTGTTTAGTTCAGTGACCACTGAGGACCTCCGGCAGGCTTCG GGGTGTACAAAGACAGCCAGGATTCAGCCCGCCTCAGTGGAGGGCCCCACAGCACAAAGGGACCAAGAAGGGATAGCAAGAGGACAGCCAGAGTGCC CACAAGCTCGGCAGGAAGGAGGCTCACATCGCCGCGGAAGTCTCGTGATGGTTCTGGTAGAATCGTCCTCTTGAAACCTTCTGCTGCCATTATTGGG TTCTGTCCAATATGCOTTACGCAAAACACTGACAATAGCATACACCTTTCCAGAATGCCGGCACGCGCTGTGCAATGCCCAAACTGTCCCTGTGAGT TGAATGCCCCTGGCAGGATGCGTGTCCACTCCCGCAGGGCCGTGGGTGCCTCCCTTGTCTCACTCCTCTGCTTCAACCCTTCCCAGAACTCTGAAGG TTTGAGATGAAATGACTGAGCCACACCTAGTGCAGGAATGAGCACCAGGGCCTCTCTGCAACGGCTGCTTAAGGGCCACAGGATAAGCATAGTGTGG CACCCCCAGTTATTCCCTGTTTCGCTCATTGGACCACCCTGATAGGCTTCAGGGAGGCAGGAACCTCCTCTAAGGCAGCAGGAGAGGGGTGGATGGG GCAGCCAACAGGTGCATCTCATGCCTCCGTGTTCTCCATAGGGAGGGAGGTGGGCTAAGAGGCGAGTGGGGCAGAGGCCTGGGCCAGCGTGAAGTGT CAGGAGTAAGGGGGGAGAAGACTGGAGGGGGCAAATCCAGGAGGCAGCTGAGGCTGCACTGTGCAAATACAAGCCCGGTTACGTCTGTGTAGCTTAG CTTCCCCAGCCCACCTGAGCCAGAGCTGGGTCTGCCCGTGCTCCCGCTTCTATTGACATCCAGCAACTCCAAATGACCTCTCCCATATCAATGGGCT CATCTCCGAAGCCGAATCTTATAGCCTGCTTCTCCTCCCCACCAGGCTATAGTGGGAAATCATTGAGGAAACTATGGTTGAATGCATCGCACGGCCT CTCTGGTGTCTGAGAGAAGCTTCATAGCCAGCAGGCTGCCCCTGGTGGGCAGGTGCCGCATGGAGGTACCACGCCTCCCGTGCAGCGAGTAAGAAGG GCAAGGAGAGCTTGTCAGGGGAGTGGGCCAGGCTATCACATCAGATGGGCCAGGCCTCGCATCGCTCTCTGCATCCTAAGCAACGTCTGGACTTGAG TGCGTGGGTTTGTGGTACTGCAATGCOCAGTACCTTGGGGAGCCCCCAGGCAAGCCAAGCCAAGTTCTGGGAGGCCACAGCCCTTCACTCAAGTTCA AAGGTTCAAGCAGGGATTCTGTGTCACACTTGCGAAGGTGCCCACCCCAACAGAAGCTGTGGCTCTGCAGGACACGTGCGGGGTAGACCTCTAAGG CCTTGTCCCAGTGGAAATGCCCTCCCACTTGGCCTGGGTAGCTGCTCACGCTTCTGAAACGGGAAAAATCAACTGCATTCCTGAATGGGAGCCTCAG AGCATTAGAAAGATAATGTTCTGATTTTTTAAAGCTAAACGTATATGGAAGGAAGCTGAAAGAGGACTTTTGATGAGTCACCTAATGTTGATGTTG AAATAACCTAATGACCCTCTGGCTAAAATCTGTTCTCATTTGGGAAGCACCTGAACCCTCATTCTCCCGCCACTGCTCTGACCTCTGGAAAGCAAG GAGCAAAGGCACACTCAGCAGCTCCCGCTCCATGCTCTCCCGAGTCCTCCCAAGCAGCCAGAGGACGACTCCACACCCAGAACCCAGAGTGGCC TGGGAACCAGGCCTCAGGTTCCTGGCCCATTTGTCATCGCCCAGGGTCCTCCTGCCAGGAATCCCCCCACATCCTGCCCTGCCTAGAGAAGCCCAGC TCTTCCATCAAAGTTCTGCTCAAATGTCACTGCATGTTACGTCTTCCTCACACACTCCCACTAGCCTTACTGCATCATGCTTGGTTTGCTGAGCTAT GTGTGGGGTCTTTCCTTGCCAACCCTTCTTTCCCTGAGAGGTGCAATGACCTCATATTGAGGCTGTCCACTCCCCCACTCCCGACCCCATCCACCAA GCCTGGGAGGCACTGGCTTAATGCATCATGGTTAAAAGAAATGGATGGTTGAATTGCACAGAGAAGACACTGTGCCCCAGGAGATGTGCCTTGCACA AGATCCCTGCAGCACATGCTGGGAGGCTCTGCCCGGGTAGCACTTAGGAAAGAAGGATGTATGCCCTGGGCTGCTGGGAGCACTGTGGGAACTCTGG GATCCCCCTCCTCCTAAGGGCTGTGCTACCCTGATTTGGAAACAATACAGAGGCTTCTCTCCTGCAAGAAAACATGCCCCCTGCCCACCCAGGATCC ACCTGGCTGGGGAATCTGCCTAGCTGGGGACCAGGTGGGCATGCTAAGGAGGAATGGGGCTGTGTCTGAAAGAAAGAGATGCCAGCAGGATCCAGGA GAGCAGTCACGGTCCTGGGGTCTGAGAGTGCTGGGCCAAGGAGGTGTGGGGAGCATAGATTCATATAAGAGAGAGTGGTTCAGTCTGTGGCCATGCT CCTGGGACACAGCACTGAGCACCCAGCAAGGCCCCAAGAGATGCTGAAACACACAGCTAGGATGGCTCCCAGGAACGTGAGACAGCATTAACCACAG GAAGCCAGGCAGAAGTGCTGCAGCCAGGGCGTGCTGTGGGAGAAGGGCTGGGAGOATGCAGCTCGCTCGCACACTGCGTCAGAAACCTTCACATAGT GCTTGTCCTCAGTACGAGCCAAGGTGGGGGTGAGGAACGGCCCACTTACCAAAACTCTCAGAGACCCCTTGGGGAATTTGTGCTTCTTGTTTCTGCA AGTTTCCAGGAGACACAGAAAGGGTGCCACTAGACTCTAAGCTGTGGGAGGCCTCTGGGAGGCTCCTTGGGTGGAGCTTAGCAGCAAGAAGGCATGT TGACCTTGGTCATCAGGAGGTGTGGAGCTGCTGCTATACAATGGGGCAGGACCCCGGCAACCCATCCGGGCACCTCTTGGCTCTCCCTGTGTGTATT GATGGAAAATGGTATGTGGAGGTGCAGCACCCCTGGACCAGGAAGGGCACCGTGACCAGTTCAAAGCCCTCAAGGATGAAGGCTTGGGTCTGGCCAC TGAGCTGTAGTTGAAAGGTGGGAGCATCTAGAAAGGACAGAGCAGGAGGCGCTCACGAGTCTTCACTGGCGTTCCAGCTGCAGGGGCTGAGGCTGGA ATCTGTTCCACTAACTTTCCTCTTCTAAGTTTTCTCCAGGATAAAGTTGCTATTTGAATTTCAGATAAACAACAAGTAGTTTCTTTAGTGTAAGTAC GTCCCAAATATTGCATGGAATACACCTATACTAACAAGTTATTCAATGTTTATCAGAAATGCCAATTTAACTGGGAGTTTTGCATTTTTATTTGC TAAAACTGGCAACCCTCCTCCAGGGATGGAGGCCCACTGGAACCAGGAGGAGCTGCCCTCAGCAGCTATGAGAGGAAATGGATCACAGCAGAACGAG GTGTAGACTTGGGTGGATGTTGCTGTGCACTGCTTGGATTCCCACTTGGGAGTGAGAGGTTCATTCCCTCGGGTACTGAGACTGCTCCTGGGAGGTG GTTCTCAGCAGGCAGCCTTCTGTGGCGATGGCTCCAGCTGGAGAAAACGAACTTCCCAGGTCACGTCTCCTCTAGAGGCAGCTGGCACCCAATGCTA GCTCAGTCAGGGCTGCGGGGGCCOTATCCCTTCACTCCACGCTGGAACAGGCTCGTCCTAGCTCCAGAGCTTTCTGCAGCATTGACTGGAGTCCATT TGGCTTGGCGTTGCATCACGGGCACCTCTCGGCCCAGTTCTGCTCCCTTCCCCTTGACTCCAACCAAGCATGCTCCCTAATCATACATGCTGACCTC CATCTCAGAGTCTGCCACCGTCCCTGTTAAAGGCTGAAGGAGGACTAGGATCACTGTCAACAAAAGCATGACCCAAGAGGCAAGACACAGTCATGTT TATAGCATATTACTATGAGCCACTCACTACTTCTAGATGTCACGGTTCAAAGGTGATTGAAAGAAACTCTGTGTTTCCCAATGCCTGCTGGATAAAT AACTCAGCATGGATGGTGAGACAGCATCTCTAACTTCGCCTGTCTCCCCGGTAATCGTGTTCCTCCTCCTCACTTCTTTATCAGGGTTCTTGGTAAT AGTAGTCCCCCCTTATTCTCAGGGGATAGATATGTTCCAAAACCCCTAGCAGATGCCTGAAATAGAAGACAGTACTGAGCCCCTTATAGACTATGTT TTTTTCTGTACGTACATAGCTAGGATAAAGTGTAACTTATAAATTAGGCACAGTGAGAGATTAACAACACTTATAATAACACCAAGCAATGATGACC ATACGCTGTAATGAAAGCTGTGGATGTTGTTGCTCTCTCCAACATCTCACTGCATGGCACTTGCCC2CTAATGGCCTGATGGCTGCCACATGGCTGA TGGGCCAGCAGCATATACAGTGGGGTCTGCTGGACAAAGCAGTGGTTCACATCCCAGAAGGGATGAAGCGGGACCCTGCGCGATGTCACCACCCTGC AAAGAATGGCATGCAACTTCAAACACAAAGTGTTGATTTCTGGAATTTTCCATTTCTTATTTTCAGACTGAGGTTGCCCTCAGGTAACTGAAACTGT GGAAAGGGAAACGGTGGATACAGGGGACTCCTGTGTCATTCCCCATCOTGGAAACCCTCCAGCAACCCCTGACTCCCCGACCGCCCCACCCCCTGCC GAGCACGTCTACTCAGCCCCATAACTGCTTGTCCTTCCCTCCTCTGCCACCCATGCACCTGCCCGTCTGAGAGCTCTCTACCTCACCCCGAGGCCTC CCCGGCCTCCTGGCCATTGTTCTCTCTCGGGCGGTACCCACACTATGGCCAGATAATTCCTCCTTTACTGTAGTTCTTACCTTATTACGGGGGAATA TGAGCCAAAGCCATGTAACTCGCTGCCGGGCAGGAACTAACAGAGCCAGCACATGCTTCTCCCGTACCCTTCTCTCCATCAGGTGGCCAGGAATGTT CCGGATCCCCGTGGCTTTGCCATGGATATCTCATTTGAACAAGAAGTAACCCCCCCCCCAGAATCTCAGGGGGTCTCGTTACCACAGCATAACCTAA CCTTTCTAGAAAGATACACTCCTCTATCCAGCATGCCTAGAGTCTTATGTGTGACAAGTGACGGTATGCTGTTTCACAAAATTTCGCTGAAAGAGCC GTTGATGAACTTTAGAATAACCCAACATTAGGCGCTGTTACAAATGGGTGGAATTAGACAAAGCCGTTTGCCTTTCACCTCTTGCTTCAGTTTTCAG AAAATTGCCCAAAGGTATTGCAAACCATTTGCGTTTTCATTGGCTTGGTTAAGGAGTTGGCAGTGTCAACTGGCCCTGTGTAAAGCCACGTCACTGT TTCTGTAGAGAGCATGACACGTCAGAGAGGTGGGAAGTGTTGCCAGGACTCTTCTTAGAATGCTGGCAAGAAGAGCAGGCGAAAAGGGAAGAGCTGT TTATAAACAGGGAAAGGAGACATCACCTCGTATCCTTGGCTTCTCATTACGTCATCGATTACAATCACAAGTCTCATTTCCTACAAGCCTGAAAGCG GGTTCTTCTCTGCATGTAGGAAAAAGCCCCGCTTACTAACTCTGCCCTCAAAGAGATCACAAGCTGGTCCTGAACGCCCTGTGCCCTGGGAATGCTT ACTGTCGAAGCTCTGCAAATTTTCTCATTGAAGGCACTCAGGGCATTCTGCTAATTAAATTAGGAAAATGTGTACAGCTCTACTTGAAAAAATCCAG GTTTATGCTCTGTATTCTATTACCAAAGAATTTATCACTTTTCAAATAACATTCAATTATTTTAAACTGAGTGTGCAGTGAGAGCATTTATAATATA ATCTCATTTCCAGAGTGTTCCATCCCAACTCCTCTCTGGTATAAGTAGCTTAGAAGGTTAGATTTTTTTTTTCCAGAGGATTAAACATTCGAGAAGA GTGGCTAAGAGGCAGCACCAGGTTTCTCTCATTTCCTCAAAGAGAATTTAGCCTTGTGAAGAAGAATAAAGTGAAGGTCAATGGTTAGATCCATGGC TTAAAAATAAAATGCAGCTTTCCTTACTCTGAATTTACCATAACCAAAAAGGCCACGAGGCAGCCATTAATGATCCTAAGTTGCAACAGAAAGAAAA AAACACCTACTTAGGGTTAAACGAGGATTCAGTGGTCACTTGCCGCCGGCCTCCACTTCACAGGGGCGGAGGATGAGGCCAGGGAAGACTTTCTTAC CCACACTGACCTGACCAGAGATGAAACTCCCCCTCCTATGACAGCCTGCACTCAGAGGCTGATTCTGAAThGTCATGCCAAATGCAGCCAATCCCT GTGTACAAGGAGAAAAAATAGTTCCTCAGAGCTGTGTCCTTGGGCCAGCCATCTGGACCTCTCACAATCTCTTTCGTTCTCCCTACACTTGGGCTGA ATCCCGCCTWCTTGCCTGCCAGGTTTGGTTTGGGGGCCAATGAGTCAAAGTCCGTGAGATACCCCTAAGTATTGAAGTGCGTAGTAAATGATAAT AGCCCTGATTTGTTGACATGATGATGTGCCAGGCATTGCGCAAGCATCATTTCATCATCACAACAAACACTGCTGGGAGGCAGGGACACCCCCAC CCTCCTTGTACACCCAGAAGTAGGACTTTGGTTAAATGGCTCTCCCAAGGCCTCACAGCCTTAAAAACTCAAGCACTTATTTAATCCCCAATGATAC TACCTTTTGGCCATGCAATGTGTCATGGCCAGTATTAGATTTGCAAACACATATAACCAAAGAGGATTAGAAGAGACATATATTCTATATAAATTA CATGAAAATAGCACTTTCAGTATTTTCCTGATTTTTTCTGGTAATTAAAAATGATTGCCCTTTATATTTCTTTATGGATACAGTTGCATTGTTTTTA GCCAATTGTAGCCCCCCCCTTTAAAGAGTGAATTAGTGGGAAAATAGTGTTATCCAAGATTTTAAGAATCTAGTGTGTGTGTTTGTGTCTGTACGAT GGGTTTTTCTGAAATATTTTACTTGCATGTGAATGTATAATTTTAAAGATTGGCTTTTAAAATACTGAATTGAGGTAAATTCAGCTTTTCTTGCAGA CTCTTTACGATAAATGTGAAATTGAAATGGAAATGCTCCATTCAGATGGTGTGCCGACTACAACCTCAACATACGGATAATTCACTAAATAAGTAA CTTCCTCGTGGAATATCAcGGTCAGCCTTTGTTTTGGGTACACATTCAATGAACTGGTTTCCTATTAGTTTCTGCTTGTCAACAAGTTGTGTCATTT ACTGATAAATATCCAGCCTTTTACTAAGGAATACCGATTTTCTCAAGTCTCAGTGTGTGGAGGGGGTGGGAGTTTGGTGGGGAAGCTTTTCAATTTG AGAACCTTTGCCGTTTTTTGTTTCAATCGTGACTAAGATATAAAAGTCCTTGGTCACCACTGCCAGCTGCTACCTGTTCACTGCCTCCCTGACGGGT AATGAGGCCATCCGGAGTTTTAGTGATTAAAATGTTTTATTACTTGTATTCACATCATCATTAAGAAAAThACTTCTAGTGGATCAATATGGCAAA TGAGTAAACCAGAAGATGGCGTTGAAGATTAGCAATTACATTTAAAAACAAGGTAGTGGTGTGAAGGCTCAGAGTTTCACACAACGACTGTTGTTCT GAACTAAAAGCAGAGGATGTGGATGAGTGAGGGGAGGGTATGTTGAAATGACTAAACCCGGTGCAGAGGACACGTATACGAAAGTGCAAAAAGCTC TCATTTGCCATTTTTTGTCCTCAGCAAACTCCTCTCTGGTATGTTTGTGAACGTTTGAGGGAAAGGTAACACTGATTAAAATATAATGCAACAAGAA GGCAACGATCTTTGCTTTGTTCACTGATGTGTTCCAAGTGCCTAGGACGGTTCCTGACAAGTAGCAGGTGCTCAATACATTTGTCAAGTGAATAA ATCTGTGAAAGGAAAGGAAGAAAAACAGGTTGTGACCAGAACTTTTTGTGAACAAAACCCTGTTGTTTATTACATAGACTTTGGTAATGGAAAACTT ACTTGGGTGAAATAAAAATGGCATCCTGTTAATTTCTGAGAACGTCTGTTGGTTTTAGGAAAAGCATACCTATCCATACCTCACTACCTGTTTTGC TCTAGCCTAAACATAGATTCTTCTTTGGTTAGGAGACATTGACCCAATATATAAGATTAAAACAAAACTGAGAAATAAGTGAAATCAAAAGCTTTT CAAAAGTTGCAGGTTGACCTACGGTGGTGGTGGTCTAAAATCATATAGAAACCAGAGATCTGATGGTTTACCTGAAAATGCGAAGTAAATGCACATA CTCAGCATCTCAGACGATCGAAAGCTCAACGGGTGAAAGCTCAGGGGGTTAATTTTGCGATTAAGGACATCTTGGAAAAGTATGTAAAATCCCTGGT CCACTTAAGTATTATTCCTATTTTGGGCTTTTATTTATTTATTTTGAGATGGAGTCTTGCTCTGTCGCCCATCTCGGCTCACTGCAACTTCAGCCTC CCGGGTTCAAGCGATTCTCGTGGCTCGTCCTCTCAAGTAGCTGGGGCCACGCCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGT TGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGCGATCCACCGCCTCGGCCTCCCAAAGTGCTGGATTACAGGCTTGAGCCACAGCGCCTGGCCTA TTTTGGGCTTTTTATACCCCACTGGTAAACTGCTTTCCTCCAGGTTGAGGTTAAAACGACATCATTTTAAGGTGAACTGAAGTCTGGAAGTGATTAAG CACTTGGATCCTTAGGGAGCCTCTCCCCGCCCCCATCTCTTTCATGCTAAGATAATTAAAACTTCGGGGCCGGGGCATTGTCTGAGTCACTTCAATT CACCAGCCTAATAGATGCAAAAGGATGTAAGCATGTCAGACACGCAGAGACAGTATTTGAATCAAGCTTAATAGCTCAAGGGAGCTGGGCCATTTCC TATTTTCTTTTTAGTGAGTGCGATGTTCTCTAAACACCGCGGAGAGGCAGGGTTCCCGGTGATGGCCTTGCCGAGGGTGCTCCCGCAACCTCCACCT CCAGTTCTCTTTGGACCATTCCTCCGTCTTCCGTTACACGCTCTGCAAAGCGAAGTCCCCTTCGCACCAGATTCCGCTACTACACGCCCCCCATTT CCCGCCCTGGCCACATCGCTGCAGTTTAGTGATTGACTGGCCTCCTGAGGTCCTGGCGCAAAGGCGAGATTCGCATTTCGCACCTCGCCCTTCGCGG GAAACGGCCCCAGTGACAGTCCCCGAAGCGGCGCGCGCCCGGCTGGAGGTGCGCTCTCCGGGCGCGGCGCGCGGAGGGTCGCCAAGGGCGCGGGAAC CCCACCCCGGCCGCGGCAGCCCCCAGCCTTCACGCCGGCCCTGAGGCTCGCCCGCCCGGCCGGCCCCGGCTCTCGGCTTGCAAAGTCCCTCTCCCCA GTCCAACCCCCGGCCCCCACAGGCCTCGGCGCCCCGCCCCGCCCCAGGCCCCGCCCCAGAGAGTTCTATAAAGTTCCTCTTTCCCACCTCGCACTCT CAGTTTCACCGCTCGATCTTGGGACCCACCGCTGCCCTCAGCTCCGAGTCCAGGGCGAGGTAAGGGCTGGAGTCGGGCAGGAGGAGGGGTGTGAGGC TGATACCAGAGAGGACCCGGAGCGCGAACCAGAGGTTCGACCTCCAGGGCAGCGCAGGGTACCCCGGCTTCGGAGCGGGAAGGGAGCGCGCCCCGTC CTGGAGCTCCGACTCCCACCCCATCTGCGCTGAGCCGGAGGCGCGGGTTTGGGCTCCAAGGCCCGCCTCCTTGGCTCTGCCCGAGCCTCCCCGCCTG CCCTCCGCGCTCCTGCGACGGGGTCGCCACAAGCTGGACGGGATGAGCTAACCGGACTGTCGGGGCCCCAGGAGTGGCTGAGGCGGGGCCGTCCAAG GCACCCACACAAGACGGCACAACTGCCTGCGAGAAACAGGCCCGGCCCTGTGGACCCCAATCCTAGGCTCCTTCCCCTGCTCTTCGTTCCTAAGGGG CCCAAGCTCACGGCGGCCTCCGGCGCGGTGCTCACCCGCTGGCGCAGGAGGAGGAGGAGCTCCACATTTGGGTCGCTCCGAGCCTTGCGTGCGGTGG CNNNNNNNNNNNNNNNNNNNNCTCCGGGGTCCGGCGGACGCTCTGCGCGCGGAATCCCCCGTACTGGGGCTGCAGCCCCCGCGTCTGCGCCACTTGT CGTTTGCAGAGCCCACTTAGTGCGCGCTAGCTGGGCAGGGATAGGGGTCCTATTCGGGGCGAAGGGTCTGGATGCGAGCAGAGAAAGCGGAGGGTGG AGGAACCCGGGGCTGCGCCCCTGGAACGCCCGGCCGCAGGCGAGGTCCTCCGCGCGTGGAGGCCGCCAGGGGAGTGGAAACTGACAGAGTOGCCGGA AGGGGCGAGAAGCGGGT1GGGAGTGAGCGAAGGCAAGCGAGAGCTGCGAGTGAGTGCGGAAGGAGGGCCAGGAGGGGTGGCGGCTGGGTGGGGAGAG AGGGTGCAAGACGAGCGGCGCGTGTCGGGAGCCTTTGGGCTGCGGGTGCGTTACAGGAGAGCAGGCGGGTAGGAGCCTTCGCGGGGGCCGAGCTCGG AAGGCGGACGGCTGTGCCCGCCCAGGGATGCGCCCGGGCCGCCGCGAAGGTGCCTTCTTCCGGGGGCCCGGACGACCCTGACACGGCACGCGCGC GCTTCGCAGCCTCAAAGACTCCGGGGCCTCGTGGTCACTGGCGCAGGGGATCGGGGCGGGGTGCCCGGAGTGCGGTGCCTCGTGGCTGAAGGGCAGC TCTTCTCCCCGCAGTGCAGAGCAGAGCGGGCGGAGGACCCCGGGCGCGGGCGCGGACGGCACGCGGGGCATGAACCTGGAGGGCGGCGGCCGAGGCG GAGAGTTCGGCATGAGCGCGGTGAGCTGCGGCAACGGGAAGCTCCGCCAGTGGCTGATCGACCAGATCGACAGCGGCAAGTACCCCGGGCTGGTGTG GGAGAACGAGGAGAAGAGCATCTTCCGCATCCCCTGGAAGCACGCGGGCAAGCAGGACTACAACCGCGAGGAGGACGCCGCGCTCTTCAAGGTCTCC GGCCTCGGGAGCCGGCGGGGGCGCGCCGGGGAGGGCCCAGAGACAGAGCCCGGGGTCCCCGGCGCCGCCTCCGAGGCGAGCCCAGGGGACCGCGCGG GGCGGACGGGCGGGCGGCGGAGGCATCAGGTGGCGTCGCCGGAGCCGCAGGAGGAGGAAAGGAGGCCTCGGCTCTCAGCGGGACCGCGGGGGCCGGG AGCCGGGTCCTGGGCGCGTGGAGGCTGCAGGGAAACCGCTGAAGGCCCGGCCGGGCCCGGGGAAGGGCGGCCAAAGGCTTGAGGGGTTTTGCGCGTT TCCGCGCCTGTGCCGGCGGCTGTTTTCGTCTCTCACCGCGTCTCTGTTTCTCTTTTCGCTGCTTTTCTCTCTGAGTCTCTCTCTCTCCATGTTTTTC CTGAGGTCAGCCTCTCTTCTCGCTCCTGCTAGCTCTCTGCGGGTACTCCCACCTCTGTCTTTCTCTTTGTGTGTCTCTGTCTCTCTCTTTCCCCCAT CGCAGTGGAACTCAGGGCCTCTGTCTAGAGCTGTCTCCCTTGCCCTTTGCGCGAGTGCACACACGTGTGTCGTTGTTACGATTGTTCTCCCCTAAGG CAGTTTACCCAGAGAACTACGTGTCTGGGCCCAGCCCCCACCTGTGGGCAGAGCAGGGGAAGGGGACTTCCTCCGGGAATTTGGTCTCAATTTGCTC TCAGAGTGCCTCAGCTGTGCTGCCATCCAGATGTCTCC2GTGGGTGACAGCTCACACCACAGCTGTCCTTAGTCCTAGGCAAGCTCACTCAGACACT GGGTGGGTAGAGCCCCCTGAAGAACCCCGCATCTCACTCTACCGGTTATAAATACCCAGAAAATGTGTCTTCAACTTGGCAGTGATAGGGTCCAA GATGGAAAATCATTTTCCTAGAGCATAGCTGGGGTCTTTCAGTTTACGTTCTGAGCAACGGTGTAAATCTGAAGGACCTATGCGCCATTCTTTCTTT TAGAAATACAATTTCAAGATTCCTTATAAAATATCTGTATTTTGGGTTTAGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAAGATGAGGT GGAAGGATGCCTATGCAACATAGTGAGACCCTGCCTCTGCAAAAAATAATAATTAAAAAAATTAGCCAGGCATGGTGGTGAACACCTGTAGGCCGAG GGCCCAGCTACTCTAGAGGCTGAGATAGGAGGACCCTAGAACTCAGGAGTTCGATGCTGCGGTGAGCTTTCATCGTGCCACTGTACTCTAGCCTGGG CAGCAGAGCAGGACTCTGATTCCAAAAAGAAAGCTAATAAACCAGACATGTATTTTGACTTTTCGTTCTCTTCATTCTTTCCCACCAGGCTTGGGCA CTGTTTAAAGGAAAGTTCCGAGAAGGCATCGACAAGCCGGACCCTCCCACCTGGAAGACGCGCCTGCGGTGCGCTTTGAACAAGAGCAATCACTTTG AGGAACTGGTTGAGCGGAGCCAGCTGGACATCTCAGACCCGTACAAAGTGTACAGGATTGTTCCTGAGGGAGCCAAAAAAGGTAGGGGCTCTCCTGA ATTTGGGTCACCTAACAGAGGCAGCCAGATCCTTGAGGCACCTTAACTTCATTCTGAGCATCACTTTCTAGCTTTCCTTTTGTATTGCCTGCCTGCC TGCCTTCTGCCTCACAGTGAAGCCCAGCCTCCTTGCCTGAGTTATGTGGGTCACAAGTTGAAATTCCTGTGGGGTTCAGCATAGGAGAATTAATCAC ACTGTATGCCTCAATGTATATGGGGGGGGGTGCATTGAATATGTGTTTTCCAGTTAGTCTTTCAAAAAAAAAAAGAAAAAAGAAAACTGGATAACTT GTTAAAATTTACTTATCTAATAGTCTTTAGTGAGTGACTATTTTGCAGAAAAGGAGTAATGAGAGGAATATCTCATCACTATGCATGGTAATAAAAC TGTCAACTTTTAAAGTGTAACATGGTCAGCTGAGGTGTTTATTAAAAGTCAGATTCCTGGACCCCTCTTTTCAAGATTCTGACCAGTGTGTCTGGAA GAGAGCTCAGGAATCTGCATCTGGAACAAATCCTTCAGGTGACCTCACTTGGGAAACATCTGGCTGGCGGGGTCCTTTATGTCACAAGGCACATTCG CATGCCATCTGTCATGTATTTCTTTACCTGTCCTGTACAACTCAGACCTTGTAGAAAAAAATCAGTTTAATAGCATGAAAAAATAACTTCCCAAGGG AGTTGCTGAAAAATACCTTATTTGTCAACACCGTGTTATGCATTCTAAGAATTAAATGCTCAGGTATTTTTACAAGATTTGACATTTAGTTAGGTCA GTTCCTGTTTTTACGTTGTGCCATTTCCCTTTTCCCCAAACATGTAGGAGCCAAGCAGCTCACCCTGGAGGACCCGCAGATGTCCATGAGCCACCCC TACACCATGACAACGCCTTACCCTTCGCTCCCAGCCCAGGTATGGTGGAGGGCACTGGGCTCCCTGAGGGCGAGGCTGTGTGGGCCAGCTGCCCACA TGGCCAGAGAACCACAGCAGCCCAGACAGCAGAACTTGCCATTTGCTATGGCTGCTCCAACAGCCCAGAAAAACCCCAGGTCACTGAACGAATGTCT CACTTTCCACACGGTGCTGCCATTGGTGTGGATTTTAAGTTGGGGAGGGTCGGGCGTGTCCGCCTGTTGGAATATGCTTCTCAGGTCTTCTGGGAAA CAGATGTTTTGTGGAGTGGAAGATTTTGGAAGTAGTGCCTTATCATGTGAACCACAGGGCAGCTGATCTCTTCAGGCTTTCTTGATGTGAATGAC AGCTTTGTTTCATCCACTTTGGTGGGTAAAAGAAGGCAAATTCCCCTGTGGTACTTTTGGTGCCAGGTTTAGCCATATGACGAAGCTTTACATAAAA CAGTACAAGTATCTCCATTGTCCTTTATGATCCTCCATGAGTGTTTTCACTTAGTCTGATGAAGGGTTCACTCCAGTCTTTTCGGATGATAAAATGC TTCGGCTGTCAGTCTATAGGGATTCCCTGAGGAGTTTGGAGGCTGTAAGAGCACCCCCCGTCTCAATGCCAGTGCTTCTTATCTCAGCCTCTCCT GCACTCCTTTACCCCCGTCTCGATGCCAGTGCTTCTTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCAATGCCAGTGCTTCCTATCTCAGC CTCTCCTGCACTCCTTThCCCCCGTCTCGATGCCAGTGCTTCTTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCAATGCCAGTGCTTCCTA TCTCAGCCTCCTGCCTCCTTTACCCCCGTCTCATGCCAGTGCTTCCTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCGATGCCAGTG CTTCTTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCGATGCCAGTGCTTCTTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCAAT GCCAGTGCTTCCTATCTCAGCCTCCCCGTCTCATGCCAGTGCTTCTTATCTCAGCCTCTCCTGCACTCCTTTAGCAGGTTCACAACTACATGATGC CACCCCTCGACCGAAGCTGGAGGGACTACGTCCCGGATCAGCCACACCCGGAAATCCCGTACCAATGTCCCATGACGTTTGGACCCCGCGGCCACCA CTGGCAAGGCCCAGCTTGTGAAAATGGTAAGGAGGATACCAGTGCAGGAAATAGAAGAGCTAACTGCTAATGTGGCCATGGGCCATGGCGAATCCTG GTCTGTCCTGGGCAGCACCAAGCTCTTTCCCCTTCTTAGAGGCTGCGTGTGCAGCTCGGGGAGAGGGGGGTTTTCTCACTCCTGTGGGATGGTGGC ATCCCACAGCCAAGTTTACTCTCAGGATCCATGCTAGGCACTGCCCTTCGTGGGATCTTATTTAAACACCACAGAGATCACTCCAGGCAGTGGAAAA CAGCCCCCCACTTTTTTATATAGAGAGGAGATTGTGGAAGCTCATAAATAATAAGTAGGGATGCTGGGAGATTATTGAGCTGGTATATTTCTCTCGAA TAGTGGTGTGTTCATTGTTGCTATTGTTGGAATTAGAGGTGATACTAAAAAGGAACGGAAAAATACCATGGCAAACACATAAAACGTCTCTACAGG TGCCTACCTACCACTGGGTCCCAGAAAGACTTGCTGATTGTGGATTAGATGTGGTCCCCTGCCCTCGGGAGTTCCCCAGACATCAAAATGAGCTCCC TCAGCAGAAGCTCTCATTAGCTGGGTGCAGGGAGAATCTAGCAATGCGGTAACTCAGGCCTTCAGGACTTTTGAGTTAGTTACTTAAATGGAAGTCC TGAGACAGGTCAACACACTGAACCCTTTGGATGTTTTAGGAATATTTGTTCCTTTGCAATTTGGCCTTTTTTTCCCCAGTCATGTTCAGGTTATCCT TGGCTGCAGGTAGTGAAGAGGTGTACCACTCTTTAATGTTTGTACTGAGTGGCATGTTCACAAAAAGCTCAGAATTCAGTTGCATTGGCTTTTCAA GAGGGATTTGCAGCAAGGGCTGGTTTCCAATATGGTAGTGGAGGAATTGGCTAACATAAAACTAGCTCCTGAAATTCAGACTTGCGTTTACTGCTCT GGCTCTATGGAATTAGTAACCATGGGAAAGAGGCAATGCTTAGAATTGTGTAAAGTGATGGAGTAGGTAGAGACCTGTCTTGAAGCATCGGTAACAG TAATGAAGCAGCAGCAAGATCAGGTGTTCTGTGCCACATTCTTTTTCCATTCATGTTTCATACAACATTGTCTTCAGGAACATGGTTCAGTGTTCT CCCAACCCACAAGAGACAAGCAAAATAAAAATGGACTAAATAATTTGCTAGTTTTAATTGGGCTCTTTGGCACAGACTCAAGTAGACCTGAACTCT CAGCTCTGTTGTGAACCCGCTTTGTGAACAAGGACAAGCATGTCATCTGTCTCTGAGCCTCAGTCTCCCTGTTAGTCAGTTACAGAGAGCGCTC CTGATCTCAGGAGACAGGCCAGCAGAGTGCTTCCCTGTGAGTCTGTGTTCCTAACTTAACAATATCTCAATATTTTGGGGAGAAATATTTTGGTT TCCTTCAGTCCCCCCTTGAAGCTTTACTTTCAGAAAGTTTCACATGTTAAAAGCTAAGTTGGTAGTTTTGGAGAGATTTGGGTTAGAAGTTTTAAGA TAAGAGATTTGGCAAGGAGGAGGAGAACATAGTTTGGAACAAGCAGAAAGGAACCAATTTGGGTACATTGTTCCATCTCTTATTGTATCAGTCTTT CAGTCCTGAAAATAGGTCAGTTCCGTTAAATCATTGCATCCCATTTCAGAGGTGGTGTAAGTGGGCTTCCATAAGAGTTACGTCTTCCATATGGTGT AGGCACACAGGTACTTTATCAGAGACATTTGTATGGAAATAAAAAGAAAACAAAGGTCTATGTTTCAAGCAGTCTATAAGCTAGTTTCTGGAGAGCA ACCAGCAGATTTCTAGATTTGGGTTCAAATAATTTTAAGTTGGAGTGGACAGGCAGTGGCAATCTGACAGATTTTTCTGGATTATAGTTTGCATC AGGCACGGTTTTAATTCCTAGTGATTTCAAGTCAGAAAGGTGGGAGAAAGTTGGGAATGTTAGTCTGAAGAGCCATAGCAGATATTAGAGGAAACTA AAACTTCAGGATTCAGTCCAGATAATTTTTAAAAACTCTAAAACAATGGACAGGGCTAGAATCTAATAACAGCTATGCTATAGCTGTTCTGAAACAT TTTTTCTCTCTACAGTCACCTCCCTGTTTACCAAAGATAATCACAATAAGTCCAGTTTACTThCAAAACAAGTTTAGTGTCATTATATTTAACCGGA TCATTTACATAAGTACAGCAAGAACAGTGATTTAACATATAAGCTCTTTTTTAAGTCAGCGTTGCTGGAACTTTTCGTAAAGAATTTTATTAGATTAG AACACTAAAACCCTCTTCAGACTAGQAAGCCGTGCCACAGACTTACCAACAGATTTTATCTGAGATACCTGGGTAAATTTTTTTCTTGAGGTCTCCA AATGTTTTGAGGTTCCTGGGCTTGTCAGAAAATGACATTATTTACTTACTGCAAGGCTAGAAGTGCTGGAAGGGCACCGCATAGTTCAGGAACAAA GTGCCAGGCCAGTTCTTTCAAGGGTTTTATTGGCTCCTTAAAGTTAACGTTCATTCCTTAAAGCAGTCTGGTCACATCTGAAAAAATGACGTCCCAG TCATAGCCTTGATGATATAACCTGTGTTTCCAATTTTTCCAGTCCGAAGAGACCAGATTCCTAGTGAACTTATGCAAATAACTATCTTGCCATAAAA ATAGAATTTCTCACATACAGTTTCTAAATCCTGGAGGGCTCAGGTAAAGAAAAAGATAAATGTTTCAATATTTGTGCACAAAAATATACTTTACAAA ATTACTGTAAAGCTGTAGATTACTTAAGAGGGAAAAAAAGTTTTCTCAACTATGGAAAGAAAACATAAAAAGAATCAGCAATGCTTTAAACAAAAAA TGTTGCAAAAAATCATTTTAGTCCTTCCTTGGTTTAGTTTCGTGTAATTCTTGTTTTGCTTGATTTGGGGTTACTAATTTTATGAGTCCAGTTTTTT TTTCATTAGCATTCTGGGAATTTTTAATGACTCCAATAATATGGTCTGAAAGTTGTCAGGAACCTGTATTCAAGAGTACTTCTTTCAGTCCTTTCTA TGAACCTTCTTGAAGACATAACACTTThGGATCTGCAAAGAGCTTTTAGAAAAAGTATCATAATAAAGCAATTAATAGCAGATAACAAGACTTAAAA TGGACATAGTTAAAGACACAATTGACATGGAAATTTGGTTACTTTCTGTGGCTTACAACAATTTAACATAATACCCATAATTATAACTGACAACATT ACCAAAACATATCAGATTTTTAGGAATCTCATACAATTTTAGAACACATATTAATAACATATCCAThTGATATAGTTTGGATCTGAGTCCCCACCCA AATCTCATGTTGAAATGTAATCCCCAATGCCAGAGGAGAGGCCTGGTAGAAGGTACTGGATCATTGGGGTGGTCCCTCATGAGTGGTTTAGCACCA TCCTCTCAGTACTGCTCTCATGATGGTGAGTGAGTGCTCTCAAGATCTGGTTATTTAAAAGTGTGTAGCACCTCCCCCACTTCCTCCTTCTGCTCCT GCCATATAAATATGCTTGGTTCCCCTTCACCATCCACTATGATTGTATGTTTACTGAGGCCTTCCCAGAAGCCAAGCAGATGCTGCCATGCTTCCT GTACAGCTGGCAGAACTGTGAGCTAATTAAACCTCTTTTCTTTATAAATTACCCAGTCTCAGGTATTTATTTATGAAGTGCAAGAATGGAGTAATAT AGAAAATTGGTACCAGTAGTGGGATATTGTGATAAAGATACCTGAAAATGTGGAAGTGGGTTTGGAACTGGATAACAGACAGAGATTGGAAGAGTGT GGAGGCTCAGAAGAAGACAGGAAGATAAGGGAAAATTTGGAACTCCCGAAGGACTTGCTGAATGATTGTGACCAAAATGCTGATAGTGATATAGACA ATGAAGGCCAGGCTGAGGAGGTCTCAGATGGAAATGAGGAACTTATTGGGAACTGGAGTAATGGTCGCTTTCGTTACGCATTAGCAAAGAGCCTCTA CTCTAAASATTTGTGGAACTTTGAACTTGGGAGCAATGATTTAGGGTATTTGGCAGAAGAAACTTCTAAGCACTGAAGTCTTTAAGATGTGACCTGG CTGCTTCTAACAGCTTATGCTTATATGTGTGAACAAAGAAATAACCTGAAACTGCAACTTATATTTAAAATGGAAGCAGAGCATAAAAGTTTGAAAA ATTTGCAGCCTGGTCATGTGAThAAGAAAGGAAAATTTCACTAGCACCTCTATCTAGGGTCTCAGGTTCTCATCTGACAAAGTACACAAAGGCCTTA CAACCCCATGTGTCCATAGATAGAAGAATAAAAAAAGACAGTCTGTAAGAGAGGAAATCAAAAGCTGTTCATGGTAGTAGAAAGGATTACCAATGGG TACCACAAAAAGTCAAGACTCATATAAATAATTAAAAACAAGGCATTTACACTAATTTGTATAAATGTTTCTCTCCCAAGCTAAGGTATTTACTAAG GAAATCAATTTGGTGGTGGGTCTAAAGAACTTTATTTAACTCTGTGTCAAATCCAATCTCTGCTTGAATGCTGCTTAATTAATTCCCTGAATAACAT TTCAAAAACATGGTAAGATTAACATCTTCCATGGGCTGAGAAAGGCTTAGAGAATTAGGCTGAAGAGTGTTTTGTCAATCTTGCAATGACTTACAGG CATTTGAAAAGTGAACTTCTCTAAAAGAAATTTATTTTAAATATAGCCAGTCTAATTTATTTCAAAGTGATGTAAACCAATAAGCCAAAATAAAAAC ACCAGAGTCACTATATCCAAGAGCCAATTTATACAAATAATTTTCTCCTATTTAAATTTGGAAATGAAGGAAAAAAGAAAAAACTCTTACCCTCCCC TCTCAACTGAGCACTAAAAATAGAGATGTGAAGAGCTGACGTTGGTAAGAAACCTTACCCTTTTCTGCTGGTTTCTTTCAGATCTCTCAGAGCTCCA TCCATTGGCCCTAGTGTGAGCAAAGTGTGCCTTTGTGGTTGTCAAATTGAAGGAAAGAAAATATGATTTATTTTCTCAATCCTCATATTTTCTTACC TGAGACACTTTCCTGAAAAAAAAAAGATTAACAAGAGAAAAGCCAGAAGAAGTTTATTGATGAATATTGTACCCATCACCTAGAAGAAGGCCTCAGT TCAAATGTATTTCTCTCCCAGGGCAGAGTAGATGAGGAATCTTTCTTAAGTAGTATTTTAACAAAAAACAATAAATCTTAGCATAGAGACAAAGCAA AGGAGGGGGCAGTTCCAGTCTTTTAAAAACTGGGAAAATGTGGGAAGATAGTAAACCTTGTTCCCAGATTGTTCTGGTGCTTGCTGATGCCTTCTCT GGGCCAATTTCTAGTAAGGAAGGATTTATGTCCTGACATCAGGCAAATAGAGGTGGGGCAGAGTGTTTCCTTGCATTTTCAGTGTGTTTAACTTAAT AATCCTCAATATTTTTGGAAGAAGTTTTTTGGTTTCCTTCATAACGAAATAGAAATAATGGACAAATAAACAATCTTTCTTCTTCTTGGGGCTCCAT TTGCTCAACAATACAGGTGGACTCAAGTCAGTATACATGCATAGGCAAGTTTTTCTTCAAATAATATATCAACTGGTTATATCTAAAAGGGTATTC CAAAGGGTTTTGAGCCCTTGAGATTGCTCTGAAGTAATTTTATGTATCTCTAAGGTACCAGTGTTTATTCTCGTAAACTGTTCTGTAACTGCAGCAC AAGTTTGGCTGTATTGGATTTGATTTCCTAAAAACAATGATCACCTGACAAACACGCTTGTTGCAGTGTGCCACCAGTACTCCCCTAGGCCAGAAAG ACACGTTGGGTCCTGTCTCATCTCTCTGCAAAGGAGCTCTGGACAGGCTATACCTAAATTAACACAGGCAGACATATATTCTCTGTTTTAGTGTTGC ATTATGAATTATATGGTGTTTGAAGGCAACCCGGCCTTTTCAGTGACCCCTCCTCCTGCCACACTGGTAGTGTGTTGGCAAAATGTCTGTCCTTAGG GAGTCCTCAAAGACTCCTTCCTTCTCTTCCCTCTGCCCTCTGCCTCTGCTCCCCTGGCTAGTCTGCGCCCACAGGTCTTGGCTGTGGCACACTCCCC TTCTGCAGGCATTGCTTCCCTTATTCCACCCTCTGTTTGGGTCTCCAAAGTGTGATATTTGTCTTGAGAAACACTTTGCCCCACTATGTCATTCCCC TTTCCTTACTCTCCAAGCAGCTGGGTCACTGGTGCTCAGGACTCAAACTGGCTGGGAATGTGAGAAAAGCTCCTTTTCCCTCCTGGCCTCCTACTTG AGACTAAAGCAAAATGCTGAGGGTTGAGGAAGGGAGAGCGAGTGCTCGCTGAGAAAGGAAGAAATGAGTGTTTAGACTTCAGCCACTCCCTGATAAA GGGGAACGATCTTCTGCCTCCTGGGAAAAACTTTGATGAGACAGCAAACTTGAGAAAAGTTTGTGGGAAGGAGCAGTGAGAACCGCAGGTTACGAAG GGGCCAGGTGGGCAGGACTGAAGGATAACTCCATGGTAACCGGCGTGGATCGATGACTATGGGGCCAAAGAGTGGGCATGCCTGGGTGTGTCTGAGC AGAAACTGCATTGAGGACAAGATCCCCTGCCCACCAGCACAGGCTCTGGCTCTGTGGGAGCTATGCCAAACTTAGCCCCAGTTCAAGGGAAGGAGAG GGAGGAGAGGGAGGAGAGGAGGAGAGGGATCCAAGTGAACTTCTTGAATTTGCATCACCCTAGTGGAATATGAGCTTAAAATTAACAATTATA TTGTTAAAAGAAAATATGAACTACATGTCTTAAAAACTTTGGCTCTGGACTTAGATTTCTACGCACCATGTCCGCAGCATAACACTGCCCATTCTTTA TTGTAATTGTCTGTTTATTAATTTGTCTTCTGTACTATAAATTCCTTGAGGAAGGGAACTGTGCTTTCCAGTAAACACCCAGTACTGGTGCAGCACC TGGCTTATAGTCAGCACCATCGAATCCTCAGGAAATGACACAGTTGGCGAACCTAGATGTCTACCATGTCCAACAGTGTCCAATAGGATGCTGGCCA AGTGATGAGCCACCTATGGCATGAAATGCTATAGAACCACTTACAAATTGTGCAGTATACAAGTATTTCATGGCATGGGGAAATGGTTGTTACTTTG TAAAGTAAAAAGAAACAGGTTTCAAAACAATGTGATATCTTTTTAAAATTTCATGGAGCTCATACATAGAATTTTTAAAAAGAACATTCAACAGTG TAAATTATACCCCTGAGATGTGGGGTCATGGAAATTTTTTATTTTCTTGTGTGCTTTTTTGTACTTTTCTCCYGTTTCTCCTGAGACATATTTTG TTACTAGAAAGGGAGAAAAGCACAAATGTAATCTTTCTAAGTTGATACGTCCCTTTATATTTTTGGTGGGCTTCCAGTTTCTCAAGCTGCCTTGTG GGGTCCCCAGAGCTCTGGGGGTGGGACCAGCTCTGAGGTGAGGGACCAGGGGCTCGGTCTCAGGGCCCATCTCCCAGTCCTGCCTCCATTAATT TCTTTTCCTACCATTTCCCCTTGATATGCTTTCCCCCACCTCATCTTTCCCAAGATGCTTCTTTGTCCTCTGAGCTATGACACTGAGGATGAACGCT CTCTCAGCTTTCTGGCTGCAGCTGCCTCCATGCAGGGACCCCCAGCCTGTGAACTTCCCTCTGGCACCCCCACTCCCCCATGCGGAAACTCCCTCGG CCACCCGTTCTCATCCCCAACCCAAGCGGGACCTCCCTCCCCACCAGCACCCCCATGCGGGACCTCTCTCCCCCACCAGCACCCCCATGTGGNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCCCTCCCACCCCCATGTGGGGATCTCCCTCCATCCCTAGCACCCCATTGTGGGATCTC CTTTCCTCACCTCCAACCCCCATGTGAGAACCTCCCTCTCACTCTCACCCCCATTCTGGGACCCTCCTGAGTCTCTCCCTTCCTCAGTCATCACAG TCTCTGTACAGCTAGGGACTGACTCTTTGCCTTTGGCCCTGCTGTTTCCCCTCACGCTAATGTCAGCATTTGGGGTTGCCTGGAAACAGGAAGGATA AGAACATTGATTCTTCTTTTTTATTTGTGGAAAATATGCATAACATAAAATTTACCATCTTAACCATGTTTAGGTATACAGTTCAGTGGCATTAAGT AATTCACATTGCTGTGCAGCCATATCCAGCATCTGTCTGCAGGACTTTCTCATCTTCCCAAATTGAAACCCTGTCTCCATCCCACACTATCTCCCCA TTCCCTGGCCCCTTTGCCCCCAGCCCCCACCATTCTACTTTCTATCTCTATGAAACTGACTACTCTGGATACCTTGTATGCGTGGAATCCTGCAGTA TTTGTCCTTCTGTGTCTGGCTTATTTCACTGAGCTTGATGTCCTCCAGGTTCGTTCATGTTGCAGCACGTGTCAGAATTTCCTTTCTTTCTAAGGCT AAATCATATTCCATTGCATGGGTGGACCATATTTTGTTCATTTATCTGTCCTGAACACTTGAGTTGCTTCCGTGTTTTAGCTACTGTGAATAACGCT GTTGTGGACATGGGTGGACAAATGGGTCTTCAAGACCCTGCTTTCAATTCTTTCATGTGTATACCCAGAAGTGGAACTGCTGGAGCGATGAAAATTC TATAATTAATATTTTAAAGGTACCACTGTACTGTTTACCACAGTGGCTGCATCATTTTACATTCCCACCAGCAATGCACAAGGATTCCAGTTTCCCC ACATCCTCACCAACACTTGTTATTTTCTGAAGAACATTGATTTTTTTAAAAAGGATTCATTCCACAAACATCTTCTGAAGACTCCCCATGTTCCTGA CCCTCCCTGCTTTCCAGGGATAGCCAGCTGTAATCGCACAGCTTCTGTGTGGGTGCAGGAGGCCAGCAAGCACTGACACAGACGCTACGGGCAGGGC ATTTCCGAGAAGGAAATATTTTCATTCTCCATTTTTAAGGTGAGAAACTGAGGCCCAGGAGTGTAAAGCCAGTACCCTAATATACAACTACTAAAAG AGGAAGCCAGGATTCAAATCCAGGCCTTTGTGGTTTCATAGCCTTATCTCTTAATTCTGATGCCAGCCTGCCTTCCCTICCACCATTGACGTACCAA GAGTCAGAGAGGTGGCACGGIYGTACCTGTATCCACACCACTGGTGAGCAGCCCTCCAGCATCACACCCAGACTTTCTAAGATGCTTGGTATCCCACA GATGGGAGCCAATTTCTTTAGGTGGGGAAAGAGAATGGGAGCAGAGAGAACAGCCTGTTCCACAAAGAAAGGAGAAGAACCAAGAGTTTGGGATTAA GCATAAAGGTCTAATTAACATTTATTAGGTGCTAAGTGCACTGCCATGTGTCAACTCCTGTTATCCTTGAAGTAATTTGGGAGACAGGCATTTCAT TTCTCACCTTACAGATGGGGGCACAGAGCACAGGGAGGATCTTGAGAGGGTCCCATGGTCAGCAAGTGTTGGTGAAAGGATATCATCCTGGCTGGTC CTACCCAGGTGCTCCATCTTCATCCTATAAAACTCTCTGTGCTTTAGTTTCTTCTATGAAACAGGACACCTATTTCATAGGGTAGTTGTCGGGATTA GTGATAAAGTGCTAAGAGTAATAGCTGGGGCACAGTTAATCCTATGTAAATATTGGCGAATTGTCTTAGTCTGTTGCCTGTTGCTATAATGGAATAC CATAGAGTGGGTAATTTACAAAGAAAAGTATGTATTTTTATGATTCTGGAGGCTGGGAAGTCCAAGAGCATGGCACTGGTACCTGGTAAGGACCTCC TTGCTGC HUMAN SEQUENCE-mRNA CGCTCGATCTTGGGACCCACCGCTGCCCTCAGCTCCGAGTCCAGGGCGAGTGCAGAGCACAGCGGGCGGAGGACCCCGGGCGCGGGCGCGGACGGCA CGCGGGGCATSAACCTGGAGGGCGGCGGCCGAGGCGGAGAGTTCGGCATGAGCGCGGTGAGCTGCGGCAACGGGAAGCTCCGCCAGTGGCTGATCGA CCAGATCGACAGCGGCAAGTACCCCGGGCTGGTGTGGGAGAACGAGGAGAAGAGCATCTTCCGCATCCCCTGGAAGCACGCGGGCAAGCAGGACTAC AACCGCGAGGAGGACGCCGCGCTCTTCAAGGCTTGGGCACTGTTTAAAGGAAAGTTCCGAGAAGGCATCGACAAGCCGGACCCTCCCACCTGGAAGA CGCGCCTGCGGTGCGCTTTGAACAAGAGCAATGACTTTGAGGAACTGGTTGAGCGGAGCCAGCTGGACATCTCAGACCCGTACAAAGTGTACAGGAT TGTTCCTGAGGGAGCCAAAAAAGGAGCCAAGCAGCTCACCCTGGAGGACCCGCAGATGTCCATGAGCCACCCCTACACCANGACAACGCCTTACCCT TCGCTCCCAGCCCAGCAGGTTCACAACTACATGATGCCACCCCTCGACCGAAGCTGGAGGGACTACGTCCCGGATCAGCCACACCCGGAAATCCCGT ACCAATGTCCCATGACGTTTGGACCCCGCGGCCACCACTGGCAAGGCCCAGCTTGTGAAAATGGTTGCCAGGTGACAGGAACCTTTTATGCTTGTGC CCCACCTGAGTCCCAGGCTCCCGGAGTCCCCACAGAGCCAAGCATAAGGTCTGCCGAAGCCTTGGCGTTcTCAGACTGCCGGCTGCACATCTGCCTG TACTACCGGGAAATCCTCGTGAAGGAGCTGACCACGTCCAGCCCCGAGGGCTGCCGGATCTCCCATGGACATACGTATGACGCCAGCAACCTGGACC AGGTCCTGTTCCCCTACCCAGAGGACAATGGCCACAGGAAAAACATTGAGAACCTGCTGAGCCACCTGGAGAGGGGCGTGGTCCTCTGGATGGCCCC CGACGGGCTCTATGCGAAAAGACTGTGCCAGAGCACGATCTACTGGGACGGGCCCCTGGCGCTGTGCAACGACCGGCCCAACAAACTGGAGAGAGAC CAGACCTGCAAGCTCTTTGACACACAGCAGTTCTTGTCAGAGCTGCAAGCGTTTGCTCACCACGGCCGCTCCCTGCCAAGATTCCAGGTGACTCTAT GCTTTGGAGAGGAGTTTCCAGACCCTCAGAGGCAAAGAAAGCTCATCACAGCTCACGTAGAACCTCTGCTAGCCAGACAACTATATTATTTTGCTCA ACAAAACAGTGGACATTTCCTGAGGGGCTACGATTTACCAGAACACATCAGCAATCCAGAAGATTACCACAGATCTATCCGCCATTCCTCTATTCAA GAATGAAAAATGTCAAGATGAGTGGTTTTCTTTTTCCTTTTTTTTTTTTTTTTTTTTGATACGGAGATACGGGGTCTTGCTCTGTCTCCCAGGCTGG AGTGCAGTGACACAATCTCAGCTCACTGTGACCTCCGCCTCCTGGGTTCAAGAGACTCTCCTGCCTCAGCCTCCCTGGTAGCTGGGATTACAGGTGT GAGCCACTGCACCCACCCAAGACAAGTGATTTTCATTGTAAATATTTGACTTTAGTGAAAGCGTCCAATTGACTGCCCTCTTACTGTTTTGAGGAAC TCAGAAGTGGAGATTTCAGTTCAGCGGTTGAGGAGAATTGCGGCGAGACAAGCATGGAAAATCAGTGACATCTGATTGGCAGATGAGCTTATTTCAA AAGGAAGGGTGGCTTTGCATTTTCTTGTGTTCTGTAGACTGCCATCATTGATGATCACTGTGAAAATTGACCAAGTGATGTGTTTACATTTACTGAA ATGCGCTCTTTAATTTGTTGTAGATTAGGTCTTGCTGGAAGACAGAGAAAACTTGCCTTTCAGTATTGACACTGACTAGAGTGATGACTGCTTGTAG GTATGTCTGTGCCATTTCTCAGGGAAGTAAGATGTAAATTGAAGAAGCCTCACACGTAAAAGAAATGTATTAATGTATGTAGGAGCTGCAGTTCTTG TGGAAGACACTTGCTGAGTGAAGGAAATGAATCTTTGACTGAAGCCGTGCCTGTAGCCTTGGGGAGGCCCATCCCCCACCTGCCAGCGGTTTCCTGG TGTGGGTCCCTCTGCCCCACCCTCCTTCCCATTGGCTTTCTCTCCTTGGCCTTTCCTGGAAGCCAGTTAGTAAACTTCCTATTTTCTTGAGTCAAAA AACATGAQCGCTACTCTTGGATGGGACATTTTTGTCTGTCCTACAATCTAGTAATGTCTAAGTAATGGTTAAGTTTTCTTGTTTCTGCATCTTTTTG ACCCTCATTCTTTAGAGATGCTAAAATTCTTCGCATAAAGAAGAAGAAATTAAGGAACATAAATCTTAATACTTGAACTGTTGCCCTTCTGTCCAAG TACTTAACTATCTGTTCCCTTCCTCTGTGCCACGCTCCTCTGTTTGTTTGGCTGTCCAGCGATCAGCCATGGCGACACTAAGGAGGAGGAGCCGGG GACTCCCAGGCTGGAGAGUCTGCCAGGACCCACCACTGGAAGCAGGATGGAGCTGACTACGGAACTGCACACTCAGTGGGCTGTTTCTCCTTATTT CATCTGTTCTATGCTTCCTCGTGCCAATTATAGTTTGACAGGGCCTTATTACTTGGCTTTTTCCAAATGCTTCTATTTATAGAAATCCCAAAGA CCTCCACTTGCTTAAGTATAOThTCACTTACATTTTTGTGGTTTTGAGAAAGTACAGCAGTAGACTGGQQCGTCACCTCCAGGCCGTTTCTCATAC TACAGGATATTTACTATTACTCCCAGGATTCAGCAGAAGATTGCGTTAGCTCTCAAATGTGTGTTCCTGCTTTTCTAATGGATATTTTAAATTCATT CAACAAGCACCTAGTAAGTGCCTGCTGTATCCCTACATTACACAGTTCAGCCTTTATCAAGCTTAGTGAGCAGTGAGCACTGAAACATTATTTTTTA ATGTTTAAAAAGTTTCTAATATTAAAGTCAGAATATTAATACAATTAATATTAATATTAACTACAGAAAAGACAAACAGTAGAGAACAGCAAAAAAA TAAAAAGGATCTCCTTTTTTCCCAGCCCAATTCTCCTCTCTAAAAGTGTCCACAAGAAGGGGTGTTTATTCTTCCAACACATTTCACTTTCTGTA AATATACATAAACTTAAAAAGAAAACCTCATGGAGTCATCTTGCACACACTTTTCATGCAGTGCTCTTTGTAGCTAAACAGTGAAGATTTACCTCGT TCTGCTCAGAGGCCTTGCTGTGGAGCTCCACTGCCATGTACCCAGTAGGGTTTGACATTTCATTAGCCATGCAACATGGATATGTATTGGGCAGCAG ACTGTGTTTCGTGAACTGCAGTGATGTATACATCTTATAGATGCAAAGTATTTTGGGGTATATTATCCTAAGGGAAGATAAAGATGATATTAAGAAC TGCTGTTTCACGGGCCCTTACCTGTGACCCTCTTTGCTGAAGAATATTTAACCCCACACAGCACTTCAAAGAAGCTGTCTTGGAAGTCTGTCTCAG GAGCACCCTGTCTTCTTAATTCTCCAAGCGGATGCTCCATTTCAATTGCTTTGTGACTTCTTCTTCTTGTTTTTTAAATATTATGCTGCTTTAAC AGTGGAGCTGAATTTTCTGGAAAATGCTTCTTGGCTGGGGCCACTACCTCCTTTCCTATTTACATCTATGTGTATGTTGACTTTTTAAAATTCTG AGTGATCCAGGGTATGACCTAGGGAATGAACTAGCTATGGAAATAACTCAGGGTTAGGAATCCTAGCACTTGTCTCAGGACTCTGAAAAGGAACGGC TTCCTCATTCCTTGTCTTGATAAAGTGGAATTGGCAAACTAGAATTTAGTTTGTACTCAGTGGACAGTGCTGTTGAAGATTTGAGGACTTGTTAAG AGCACTGGGTCATATGGAAAAAATGTATGTGTCTCCCCAGGTGCATTTTCTTGGTTTATGTCTTGTTCTTGAGATTTTGTATATTTAGGAAAACCTC AAGCAGTAATTAATATCTCCTGGAACACTATAGAGAACCAAGTGACCGACTCATTTACAACTGAAACCTAGGAAGCCCCTGAGTCCTGAGCGAAAAC AGGAGAGTTAGTCGCCCTACAGAAAACCCAGCTAGACTATTGGGTATGAACTAAAAGAGACTGTGCCATGGTGAGAAAAATGTAAAATCCTACAGT GGAATGAGCAGCCCTTACAGTGTTGTTACCACCAAGGGCAGGTAGGTATTAGTGTTTGAAAAAGCTGGTCTTTGAGCGAGGGCATAAATACAGCTAG CCCCAGGGGTGGAACAACTGTGGGAGTCTTGGGTACTCGCACCTCTTGGCTTTGTTGATGCTCCGCCAGGAAGGCCACTTGTGTGTGTCGTGTCAGTT ACTTTTTTAGTAACAATTCAGATCCAGTGTAAACTTCCGTTCATTGCTCTCCAGTCACATGCCCCCACTTCCCCACAGGTGAAGTTTTTCTGAAGT GTTGGGATTGGTTAAGGTCTTTATTTGTATTACGTATCTCCCCAAGTCCTCTGTGGCCAGCTGCATCTGTCTGAATGGTGCGTGAAGGCTCTCAGAC CTTACACACCATTTTGTAAGTTATGTTTTACATGCCCCGTTTTTGAGACTGATCTCGATGCAGGTGGATCTCCTIGAGATCCTGATAGCCTGTTTCA GGAATGAAGTAAAGGTCAGTTTTTTTTGTATTGATTTTCACAGCTTTGAGGAACATOCATAAGAAATGTAGCTGAAGTAGAGGGGACGTGAGAGAAG GGCCAGGCCGGCAGGCCAACCCTCCTCCAATGGAAATTCCCGTGTTGCTTCAAACTGAGACAGATGGGACTTAACAGGCAATGGGGTCCACTTCCCC CTCTTCAGCATCCCCCGTACC HUMAN SEQUENCE-CODING ATGAACCTGGAGGGCGGCGGCCGAGGCGGAGAGTTCGGCATGAGCGCGGTGAGCTGCGGCAACGGGAAGCTCCGCCAGTGGCTGATCGACCAGATCG ACAGCGGCAAGTACCCCGGGCTGGTGTGGGAGAACGAGGAGAAGAGCATCTTCCGCATCCCCTGGAAGCACGCGGGCAAGCAGGACTACAACCGCGA GGAGGACGCCGCGCTCTTCAAGGCTTGGGCACTGTTTAAAGGAAAGTTCCGAGAAGGCATCGACAAGCCGGACCCTCCCACCTGGAAGACGCGCCTG CGGTGCGCTTTGAACAAGAGCAATGACTTTGAGGACTGGTTGAGCGGAGCCAGCIGGACATCTCAGACCCGTACAAAGTGTACAGGATTGTICCTG AGCCCAGCAGGTTCACAACTACATGATGCCACCCCTCGACCGAAGCTGGAGGGACTACGTCCCGGATCAGCCACACCCGGAAATCCCGTACCAATGT CCCATGACGTTTGGACCCCGCGGCCACCACTGGCAAGGCCCAGCTTGTGAAAATGGTTGCCAGGTGACAGGAACCTTTTATGCTTGTGCCCCACCTG AGTCCCAGCTCCCGGAGTCCCCACAGAGCCAAGCATAAGGTCTGCCGAAGCCTTGGCGTTCTCAGACTGCCGGCTGCACATCTGCCTGTACTACCG GGAAATCCTCGTGAAGOAGCTGACCACGTCCAGCCCCGAGGGCTGCCGGATCTCCCATGGACATACGTATGACGCCAGCAACCTGGACCAGGTCCTG TTCCCCTACCCAGAGGACAATGGCCACAGGAAAAACATTGAGAACCTGCTGAGCCACCTGGAGAGGGGCGTGGTCCTCTGGATGGCCCCCGACGGGC TCTATGCGAAAAGACTGTGCCAGAGCACGATCTACTGGGACGGSCCCCTGGCGCTGTGCAACGACCGGCCCAACAAACTGGAGAGAGACCAGACCTG CAAGCTCTTTGACACACAGCAGTTCTTGTCAGAGCTGCAAGCGTTTGCTCACCACGGCCGCTCCCTGCCAAGATTCCAGGTGACTCTATGCTTTGGA GAGGAGTTTCCAGACCCTCAGAGGCAAAGAAAGCTCATCACAGCTCACGTAGAACCTCTGCTAGCCAGACAACTATATTATTTTGCTCAACAAAACA GTGGACATTTCCTGAGGGGCTACGATTTACCAGAACACATCAGCAATCCAGAAGATTACCACAGATCTATCCGCCATTCCTCTATTCAAGAATGA

[0301] TABLE X MOUSE NOMENCLATURE ICSGNM Notch1 Celera mCGI8747 HUMAN NOMENCLATURE HGNC NOTCH1 Celera hCG178O817 MOUSE SEQUENCE-GENOMIC GTCTGGAGGTTTTATTTGTCCCTGAGGGGGTGCCATTTTGCTTTGGGGGTATGATATGAAGAACCTGTGTCTGAGAGCGGAGTTGTAGAGAGTGGGC AGCAGCCAGCATCCTGGCATAGTCCCCTTGCTACAGGGCAGGAACTGAAGAGAGAGAAAGCACACACAGTCTCCAGTCTGCTCTGCTTCCCGCGTCC ACTGTGCTATTGATGTTTGAAAGTGGAAGGAACCGTGAACTCTTTTATTACCCAGATGATGCATATTCATGACAGAAGCTGGGAGAGAAAAGCAGAC CAGCCTCCTAAATGAGAGTTTCACAGAGTCTATGTCGACATCCCCCCACAGGGCTGGGGGGAGGGGGCTCTGCTGCGCCTGTAGGCTCACTTCGAGT GTAGACCCAGATTTGAAATCTGCCTGGTTTGAAATTCAGGCTGGTCTTGTCTCTAGCCTGGCCCCAATTAACAGTCATTATTATTTCTTTTITATTG AGGTGAOGTTCACTTAGTATGTGAAAGTAACCCCTTTAAAGTGAGCGCCTCCATGGCATGCTCCAGAGCTTACGTCATCCCAGAAACCTCTGCCCAG CAAGCAGCCACTGCACCTCCATTCTAGAGCCTGATTCCAGTTGCACCCACTGCCCAAGGTCGGGTAGCCTGTGGCCATGAGAGATGAGGGCGGGGAG CTGACTGCCCTACATGTCTGTCAACAGCTGCAGCGGAGCCTTTGTGGGCCAACGATGCCAGGACTCCAATCCTTGCCTCAGCACACCGTGTAAGAAT GCTGGAACGTGCCACGTTGTGGACCATGGTOGCACTGTGGATTATGCCTGCAGCTGTCCCCTGGGTTTCTCTGGGCCCCTCTGCCTGACACCTCTGG ACAACGCCTGCCTGGCCAACCCCTGCCGCAATGGGGGCACCTGTGACCTGCTCACTCTCACAGAGTACAAGTGCCGCTGCCCACCAGGGTGGTCAGG TAAGGGCTATAOGAOGTTGTGAACTTCACGGTTGGGACCCTTAGGCCTGGGCCCAAGGACCCTATCTTTGTTGACTTGACATACTCTGGTACACTAA ACTTTATCCTCTCCTGGATCAGAGTTAAGCTGGGATCTACTATCCAGAAAAATCTTGGGGATTCCTTGGGAACTCTGGTCCTTTTCAACCCCAAACT ATCTGATTTTTGGCTGCCCTGTTCCAGGACCCCAACCTCTCACTGTTTCTGTGCGTAAAGAATGAGTCCTCATGTAGCCCGGGTCTTACCATCTCCT TGTCAGGGTGCCTCAGGTTTCCATTGCTTCTCTATGTGGGGTCCAGGAGACAGCTAGGTACAAATTTTAGACTGCCATTCCTACTTTCTGTCCTTGA GCAGTCACTTAGTCTCTTATGACTTACAGTCCTCTGTATGCAGAAAGATGGCCACATTCTGCAACAGATACTGAGCATCATGAAGATAACACTTTAG ATCTATCCCTGGTTGGTACCTACATGATGTCCAAATCTGCCCTGGGTTCACAGGGAGGCCCTGGCAACAGCTGACCCTCTTCTCTGCCTCCCAGGAA AATCATGTCAGCAOGCTGACCCCTGTGCCTCCAACCCCTGTGCCAATGGTGGCCAGTGCCTGCCCTTTGAGTCTTCATACATCTGTCGCTGCCCGCC TGGCTTCCATGGCCCCACCTGCAGGCAAGATGTTAATGAGTGCAGCCAGAACCCTGGGCTGTGCCGCCATGGAGGCACCTGCCACAATGAGATCGGC TCCTATCGCTGTGCCTGCCGTGCCACCCATACTGGTCCCCACTGTGAACTGCCCTATGTGCCCTGCAGCCCCTCACCCTGCCAGAATGGAGGCACCT GCCGTCCTACAGGOGACACCACCCACGAGTGTGCCTGCTTGCCAGGTAGGTTCCATCTCAGTATGCTGGCATCTAGCCTGGTTGTCCATGTCCATGC GTGTTCCACTGTCAAGCCCGAGGGATGCAGAAAGAGTTAATACCCTTTGAAGGGAGCCCAAAAAGAAOTTTAGAGAAGGGCAGCAGCCATGGAGCCT TAGGTGTGGTATAAGAGCAGGTCAGGATAGGGATACCAGAAGTGAGGGGACACTCTCAGTGACACCACACACGTCTATTTCTGTCTGGGCCATCTAC TGAGATCCAGTTAOTTTGGTGCATAACCTCCAAGCCTTCTTTCTGCTGATAAGAGTGCCTTCCCTTGGTATTTTCTTCATGCTGOGCCTCCCCTGAC CCATAGCCAACTAATACCCACCATGTCAATACCCTGAGCCTCTTAGGGCAGGGAGCCAGCCTGCCTTTACAGATGCTCATGAACTGTTTGGAATCCA CATGTGACTCTCTOTATGTTACGOGAGCACCCTGTCATGGGCAGTCCCTGGGGTTTCCCCTTTCTCTGGGGATGGTAATTGAATAACAGGGTCTTGA GGGCCTTAGGGGCCTCACGTTTTTCATTACTTCCTCTGCAGTGTTCTTCCCACTGTGCTCAATGTCTCTGCAGGGGTOGGGCCTGCAGGCACAGCCC TAGTCCTTTCTGTTGCTGCTCTAACGATGGTAACTCGGTGATCTAAGGCAGCTTGGAGCTGCCGCCAACCCACTTTTGGCAAGGGTGGGGTTGGTCA ACATACCAGGCCGTTGAGAGGAAGGAOGAGTGGGCTCAGGAAATAGGAATAGATTTGGTTGCTGGGGCTGACCTCGGACCACTCCCCTTGCAACCCC GGGGCCACCCTACACACTGAAAAAGGGAAGTTCCCTTCTGCCCCAAGCTTGCAGAGCCAGCCTCAAGACTGCGTOCAGACACTGGCTTATACATTTC CTGAAAGTCATTGGGCAAGCTCGGAGGTAGCCGACAGCTGCCTACACGCTTCCCAGCCTCCCTGGGGGGGCTGGOACAGGATCCTCACGCTCAGGAG GGCCCCAGAGCTGAGTTCAGCTCTGTCTTGGTGGCCACCTAAGACCTCAGCTGTTAGAACCTGTGTTGAGAGGCTAGACTGGGTCTGTCATGCAGAC TGAGAGAAAGCCTTGTTCAAGGAGCTTGTGAATGGAGCTGCCACCAATCCACCTTAGGCAGGGTGGGGTGGGTCAACTCAGAGTGCTGGAAGATGGG CAGGAGGGAAGCAAGGACTGGGTGGGGTCCCTTTACCTTAGCCGGTGGGTCATCCCTGAAGACGGAACACACACTACCCTGTGCTGTGTGGAGACAT GCTGTTTCAGAGTAGGGAGAAGTGAAAATTOTCCACCCAAATTGCTGTTGAAGGGAGTCCGGTCTGGGCACAGTTATACCCACCATTTGGGCTCCCA GGTAGCTATTTACCAGGTTTCTGAAGAATGTATGAACTAGGGTGGACATAAAGAACTAAGATGGOAACAGAACTTAAGCCTGAGAGCTGACTGGGAA TTAAAGCGACTCTOGCTCCTGTATATCTATCCTCTCACTCTCTCACAAGCCCGGTTTCCCTGGAGGAGGCTGTATAGSCAGAGAAGGCTTTGGCCAG GCTCCACATAGGACCTATGATCCCTTCTCCTCGCCCCCAGTGAAATCCTTCTACACCTGCTCAGGGCCCCTCCAGGCTCGCTTCTTCTTGGAAGCGT GCCCTGTGCTAGAATAAATCTCTGCACAGGCAGGGAGACAAGCTATTTGGTCTTGCTGACCCCTGGCCGGGCACTAGGCTCCAAGTTGGTTCCTCCC TCACCCAGATAAGCCTTTTCCAAGCCTCCAOCTTCTTGCTGTGGTGCAAGATGGTGGGGTGGAGGGGCATCTTTGAGGAGGAGGCAGACAGGTGGGT TCTCCAAGGGCAGOAGGGGTTCAAAGGCATCCCCAGAGATGGTGTTAATTAGTAACCOGCTGCAAGTTTGGCTGTTGCCAGACTCGCCTTTCTGGGT TGATCATTGACCCOGCAGGAGTTGAGGAGATTAATAGCTAACTAGCTGCTGAGCAGGCCCTCAGGAAGCCACACrGCAGGCCACACCTTGGGGCCCA GCCCCAGGCTAGATGGGCTTGTAGAAGAGAGATGGTTGCCCTGGCTGTGCCCTGAGGAAATCACAGGTTCTGACTGAGCGGGCCTGCCTGGATCCCA CCACTCTGGTTTCTAACTTAGTGCTCCCAAGCCCCACTTTTAGCTCCAGCAGTTTTAGGTATTCGTGGCTGCCCCACTGATTCAGTGTGGACAACCA TAGAGTGCAATCCTCTGAAACTCTGTTAGTGGTTTTGTGGCAGAACCTCCAAGOACACTATGTTCCTAGATCCCTGTCTGTTGAGTCAGCTCTTTAC ATAGCGACTTTCTAGAGAAGAGCTGTCACCTGTGGACACGGGAGTAGOGATGCCACGGAAGGACAGACAGATGCCTTGTCCAGAQCAGAACATTGCA GGTCCACCCAGAATCTGAAGATACCGGAGCCCACCCGAGGCTCCTCAGCAGACTTCTGAGGTCAGGCTAACCTGCTGGCTGGCCCCTGTCCCACAGG TTTTGCTGGACAGAACTGTGAAGAAAATGTGGATGACTGTCCAGGAAACAACTGCAAGAATGGGGGTGCCTGTGTGGACGGCGTGAATACCTACAAT TGCCGCTGCCCACCGGAGTGGACGGGTATGTATATGGGACTTGTAGGCAGCAGCCTTCCACTAACAAAACTGCACACCGCGGAGTGGTAGGAAGGTC TGAACTCTGTTCCACGCTATGAAAGCCCACACTGCAAGACCCAGGGTGGCTGGTAGCATGGGAGCAGCAGCTTCTGTOCTTCCAGTTGGAGTCAGCA CAGCTCAGCATCAOATGGTTCTTGTGAGCTATTAGCAGCTAACATCCAGAGTCAGGCCCCCAGCACTGAGCCATACAGGAGCTAGCATTCTGGGCAA GCTACCAGGGATGAATACAAGGTTGTCCTCAGCCCCACAGCCCAGAGCACGGAGCTCATCTTGTAGCTGAGGTTGATGTTCCTGTGACCCCTCATAG GTCAGTACTGTACAGAGGATGTGGACGAATGTCAGCTCATGCCCAATGCCTGCCAGAATGGCGGAACCTGCCACAACACACACGGCGGCTACAACTG TGTGTGTGTCAATGGGTGGACTGGCGAGGACTGCAGTGAGAACATTGATGACTGTGCCAGTGCCGCCTGTTTCCAGGGTGCCACTTGCCACGACCGT GTGGCTTCCTTCTACTGTGAATGTCCGCATGGGCGCACAGGTAAGTCGGTGCAGGAATGTCCTGGGAGAAGGGAAACTTGGTTGGCTCACCACCCCT GGTGGAAACACCTGGGGAGCCATGTATGAGATATATATACAGATATATGTGTGTATATACATATATATATATATATATATATATATATATATATATA TATATCAGATATAGATACAGCTCAGATGTAGATACAGGGCTGGAAATGCAGCACAGTTGGTAGAGTGGCTGCCTAGCATGCACAGGATACTGGACTC AATCCCTAGGACCACATAAACTGTGGGTAGTGGCACGTGCCTGTCAAGCCAACTCCCAGGGAAGAGTGAATCCAAAGGTTAAGGCCATCTTTAGCTA TATAGCAAACTTGAGTTCAGCCTGGAATATGTGAGACCCTGTTTTAGGAAAGGGATGGGGAGAGAGAAAGCTCTGTCTCTTTGGCACCTCCAGCAAT GACCCAGTAAGCCTTGCTGGACAGAGGCATCCTGGTGATCTGAACTTTGTGGGATGCTTGAGTGAGTCAGAGAGATTCATTCCAGGGTGTTGGGTGA GGATGGCCCTGCTGCAACAACCTGTTAATCCCAGGATAGGGAAAAGCAGCACCCACTCACCGCAGCTGCCTTGTCTAGGTCTGCTGTGCCACCTCAA CGATGCGTGCATCAGCAACCCCTGCAACGAGGGCTCCAACTGTGACACCAACCCTGTCAACGGCAAAGCCATCTGCACCTGCCCCTCGGGGTACACA GGGCCAGCCTGCAGCCAGGACGTGGATGAGTGTGCTCTGGGTAGGTACAGATGCAGTGGCACAGGCAGCAGGAACGGGCTGGCTGTCACATATATGG GATGTGATCTGTCCTGGAGAACCACCATTTTGATGGCCTGGGCTGGGGCATTGCGGGTGGTCQGGAGGCTGCAAGGCCAGATGAGCCCTCATCCGTG CCTCTTTCACCAGGTGCCAACCCTTGTGAGCACGCAGGCAAATGCCTCAACACACTGGGTTCTTTTGAGTGCCAGTGTCTACAGGGCTACACGGGAC CCCGCTGTGAGATTGATGTTAATGAGTGCATCTCCAACCCATGTCAGAATGATGCCACTTGCCTGGACCAGATTGGGGAGTTCCAATGCATATGTAT GCCAGGTATGTCTTATGCCATTTCCCACCATGGGGGCTGCTAAGAGCAGGCAGCAGGGGAATGAGTCAAGGCTGCATAGCTTCAAGTAACATTTCTG TCATGGTTGGTAGCATCTGGGAAGCCGAGGCCAGGATAACAGGACAAAGTGGAGAATGTACCCAGAGTTGGGTGCATAGACTCAGTAGATATAGACA TGAACCACAGTGGGCACACTAGGCCCGTATGAGGGAGGGTTATTTCTCTCCCAAGTCTTCAGCTGGGGCTCTAGAAGGACCTACCGAAGCCGTCCTC GGTCTCACCATCTCCCGTCCACAGGTTATGAAGGTGTATACTGTGAAATCAACACGGATGAGTGCGCCAGCAGCCCCTGTCTGCACAATGGCCACTG CATGGACAAGATCAATGAGTTCCAATGTCAGTGCCCCAAAGGTGAGGCCACCTACTTACCACAGGACCCGTATCCTCATGATCTCTTCCCAGACTCC TTTGAGGGAGGACTTGAGTTGACTAGGGCGTTTTCAGGCTTTCCTCAAAAGGTAAAGGCCCACGTGAGCAGTGGACGCTGTAGGGGACCTGGCACCG GAAACCCTTTACTAAAGGAGGGAAGGATGGGCAGGAGCTGCAGCGCTCCTAAGATAGGAGAGTCCACCTGCTTGGCTCTGTCCTCTTCCTGATGGTC ATGGGAGTAAGGACATAGTGTGGGGATCTGACCTCTATGCCTGGGAAGGACTTGGAGGAACTGAAGAGGGGACCAAAGTCCTGGGAATCTGTCTCTT GCCTACTCCAGGGCTGGACCAGGCCTTGGGCCTTCTGAGATGTAAATAAGCCATCCTAGACTTGGTCCAGCTAGGGGAGTCCCATTCACAGCCTAGT GCAGCTGTAACCATAGCAACCAGAGTCTATTTAGGAAAAAGGCCCCTCTGTTGGGCCAAGGAGGCAGCCACTGAGCAGTGCTAAACAAGGAGCTGAT TAGAGGGGCAGGGTGCAAGGGGCAGGATATAAGGGCTGGTTGAAGCCTGGAGGTTAGTGGCCCCTGTTATCAAAGTACCCTCTAGGGAGCCCATGTG AGCAGACATTCAACTCTAAGGTTTGTGGGTAGCAACCAAGGGGTTAGGATACTGTCAGATATAACCATCTCGTCTTCCCTGGCCACAGGCTTCAACG GGCACCTGTGCCAGTATGATGTGGATGAGTGTGCCAGCACACCATGCAAGAACGGTGCCAAGTGCCTGGATGGGCCCAACACCTATACCTGCGTGTG TACAGAAGGTACAAGAGGCAGTGCAAGATCTGGGGGAGGGAACTCTTGAGGCTAGATAGTGCTGAGAAGGGGACAGGAAACTGGGGAGGCCTTAGTT TGGGGCCATATAATCTGAGAGTCAGAAACTTAACTCCGCTTGGACTCCAGGCAaGAGTGATGAGAACATCCCTGGGTATGTGATACCCCACATCCAT CGATGACCAGGCAGTGATCCTGGGCCTGCTCGGTGGTTTGCCAAGGTGTGGCCAACTAAGTGTTGAGGGAGTAACTGGCCCTGAAGCTCACTAATGT CCACCTTTCCTGCCATCTAGGTTACACAGGGACCCACTGCGAAGTGGACATTGACGAGTGTGACCCTGACCCCTGCCACTATGGTTCCTGTAAGGAT GGTGTGGCCACCTTTACCTGCCTGTGCCAGCCAGGCTACACAGGCCATCACTGTGAGACCAACATCAATGAGTGCCACAGCCAACCGTGCCGCCATG GGGGCACCTGCCAGGACCGTGACAACTCCTACCTCTGCCTATGCCTCAAGGGAACCACACGTGACTGGCCGGAGCTGGCAGTGGGTGGAAAAGGGTG AGGCCAGGCTTGGAAGCTGACCACATGTCATGCTGCCCCTAGGGCCCAACTGTGAGATCAACCTGGATGACTGCGCCAGCAACCCCTGTGACTCTGG CACCTGTCTGGACAAGATTGATGGCTACGAATGTGCCTGTGAACCAGGCTACACAGGTGAGTGGCTGAAGGCAGAGGTCAGGGTCATCCCTAGAGTC TGGGAGGGACTGTGGGGCTAGCCAGGGTCCAAGGGCTGGATGTCACAAGCTGGGTGTCAACTACCCAGATCTTGATCTGCCAACCAGTAGAGGTATC TATCATAAAGACTGGGTGGCCTCCATATGCCTCCTTTCCCCTGTCAGTGTCAGCCCTGGCCATGCCAGACTTAAAGCCCCAGTAGCCTGAAGTGGGG TGGCCAGAGCTCCGAGGCCAGGCTTTTGGATATGTGTTTAGATCTGATAAAATCCTTAGTTTCTCTGAGCACCGAGGACATTGTCCACCAGAGGATA GAAGAGGATGGGTGGTCTCAGGCTGAGGTAAAGCTGGGCTGCAGAGTGACTCAGTTGGTAAGGTGTTGACCTAGCATGTGTAAACCCTGGGTTCAGT CCTCCTGCCATGTTAACCAGATGCAGTGGCATGCATACGTTGTAACCCTAGCACTCTGACATTGGAAGCGAGAGGATCAGAAGTTTAGGTCATTCTC AGCTACATGTGAGTTTGTGGCCAGACTGGATCACATGAGGCTCAGAAGCTACTGGCACTACGGTCATGTAACTCATCGATACATAAGGCACTTTACT ATCGCTCAAAGTTTCATAGATTAGCACAAGGGGAAACTTAGACCCAGCTAGGTCTAGCTCTAGGAGGGGTAGGCTCTGGGTGGCAGGCCTGGAATCT GAGCCCCTTCCCACCCACAGGAAGCATGTGTAACGTCAACATTGACGAATGTGCGGGCAGCCCCTGCCACAACGGGGGCACTTGTGAGGATGGCATC GCGGGCTTCACTTGCCGCTGCCCCGAGGGCTACCATGACCCCACGTGCCTGTCCGAGGTCAACGAGTGCAACAGTAACCCCTGCATCCACGGAGCTT GCCGGGATGGCCTCAATGGGTATGGCAGACTGACCTGGGAGGGACTAGCTGTAGCCTTGGGCAGACACAGGCTGGGTGAATGGGTGCTCCTGTGAGA CCAGTGATCTGAGGTCAGCCCCTAGTGTCTTCCCAGCATCCCTGGGCTGTATCCTCATTGGCTAGCATCAGCTCAGGATATAGACTCTAAGCACACT GTGGCTGCTGAAACAGTTGTCTGATACTGTGGTGACAGCAGCCCTTTGTCAGTGTGTGGGGGACGAGGAGATTACTAAGGTCTCCGTTAAAACTATT AAAGTTTTATACAGAGGGTCAGCATTGTCAAGGTGGCATTGTTCCAGTCTGGAACCCTTGCACGGTCTTGGGCCAGGTGGGTACCTCCAGCCCAGTG GATGATGTGGCCTTGTCCTCAGACTGGAACTGTAGTTTAGCAGGAGAGCTCTGAGCCCAGGCTACAGCTCAGGCCTCTCCGTAGGTACAAGTGTGAC TGTGCCCCTGGGTGGAGTGGAACAAACTGTGACATCAACAACAACGAGTGTGACTCCAACCCTTGTGTCAACGGTGGCACCTGCAAGGACATGACCA GTGGTTACGTATGCACCTGCCGAGAAGGCTTCAGTGGTAAGTGTGGCGGGTGACACAGCAGAATGGGTCCTCCCTTTGGTCTCTTTCTCGGTCCACC TGATGAGCTAGCATTTCTCAGGCAGAGATCCTAGTTCTCTTGAGGAAAGGCATAGGGCAGAGGOTCTGGCCCACCTCCTCTTGCTCAACTTCCTTAC AGGCCCTAATTGCCAGACCAACATCAACGAATGTGCCTCCAACCCCTGCCTGAACCAGGGGACCTSCATTGATGATGTCGCTGGATACAAGTGCAAC TGTCCTCTGCCATATACAGGTACGAACAGCCAGGGACTGGAATTGGCTCTGGTGGTAGCTAGTGGAGCTAAGAGTATATGGGCTTACCAGGCACTGA AGAAGGTTCTGTTCCTCGCtGAGGGTCTTAGGTCCTCAGACTGGAACTGTAGTTAAGCAGGAAGGCTCTGAGcCCAGGCTACAGCCCAGGCCTCCTG GGCCTGGGGATAGTCACCAGATGGGCAAACACAGAGGATGCCTAGGAGGAAGCTCCAGGCCGTGTGTCCGGGTGTTTATCTGGTATGTCTGGAGTGA GGTGAGCACTGGACTCCTCCAGAGAAAGTCTGGGAGGCTGACTGGTAGGTACTGCATGGATCAGGGTCCACTTTGCCTGTGCCTCTGGGGGCCCTGG CTGCCCTCCTCTGCTGGCTGGGCCTGGGATTCCTTTGATGGCAGCTTCTTTGTGTGAGGAGACAAGGAGCCCCCTGTTAGATGAACAGAGGCAGCTC CTGCCATGGGCACTGCCTGAGGAATGGCGAGAAATAGACCCCCTGCAGGAGAGATGTGCATTGAACATGAAAGcCGTGACCACATGGCCCCCAACCC TGCAGCTCCCAATACTOCCACAGAGTACTGGTGGCTTCATGCTGCTGCTGCTAGGTTCTGGACATAGCAAGTGGGTCTGTGAAGGTGGAGGCCCTTC CAGTGTTCCTATGATGCCTGGCAGGATGCTGTTTTCTTTGACAAAGTTAAAGGGCCTGGATTTTGTCTCCTGTGTTGGTCAGTGAGGAAACTGTCAG AATTGTCGGAAACTCTGTCAAAGTTCCTGTCTGCCCAGGTCACCGTGGAAACCGATAGAGAGAGAGGCCCTGGAGAGTCTCACCAGTGGGCTGGGGA CATGGTGGGAGACAAGGAAGATAAGGTTTCCTTGCTTAGCTCCTGGAGCCAACCATGGCCATAAACAGGAAAGCTAACTGGGATTGCAAGGAGAGTC ACCTGGGTTACTCGTGGCTCCCCCAAGCGGTTATCAGATTTCACTGCCCTAGTGTGAGGCTGCACCCCATGTTCCCCAAGTAGGATATGCTTGGGGT AGCCACAGTAGCTCTGTCTCAGGAGTGAGCCTGCTGTGACCTAAAGCTTCAGAATCAGCTCAAGGATTTTCCTGGAATGGGGAGCAGGCCAGGTTCC TCCAGGCTCAACCACCTGTTATAGTAGGGTCTTGTTTTGAGGTTTTCTGGTTGGGCAAGGCCCAGGCTTCATCGTGGAGCATTTGGGAGATGAGAGA TGGCTTCCGGGACTACATAGATGGCTCATGGAGAAAGAGTGCTTGTGGAAACATGAAGCCTGTTTCATGAAAAGAGGGTACCTCTAAATGCCCATAA CCCCAACATTTGGGAGCAGAGACATCTTGAGAGCTCTCTGGCTGGCCAGCCTAGCTAAGATGGCAAAGCATCTGATTCAGTGAGACTCTGTCTCAAA GGAATAAGATGCGGGGTTGGTAGAGGACACCTGATATCCGTCTCTCCTTCTGCATACACTCTTACACACCTGCATGCAATATACTATGCTCGTTAAA AAAAAAAAAAAGTGACTTAAGAGAGAAACTTGATTCTGCTTTATCTCTAACCTCCTGTCAGTAATCGTCATTCCTCCCGGGATCAGAGTCTGGCTGG CCAATCATACAGCATCTCCTATACCTACCCCCCGCCCCCCTTTATGGAAGACCCTATGGGCCAGGCTCACTGGGTTCTATCTTCTACAAATCTTTCT TTCTAGGAGCCACGTGTGAGGTGGTGTTGGCCCCATGTGCTACCAGCCCCCTGCAAAAACAGCGGGGTATGCAAGGAGTCTGAAGACTATGAGAGTT TTCCTGTGTCTGTCCCACAGGCTGGCAAGGTGAGGCTTGCCTGGTCCCACCAGGCTGGGACAAGGATGGTGGATGGGAAGTCAGGGGCCCTGGCCAG CCTGTGGGGCAGTCTCGAGAAAGGAGCCCATCAATGCTGAGCTACCTGCTCTGGGAAGCTCTGGGAAGCTCTGGGAAGCTCTGGGAGCAGGAGATGG TCCTTCCCATTCCAACTCCATATCCTTCTGTTGCCCAGAGGTCAGGGGAGAAGCTCTGGAGATAAACAGACCAGCTAGGACAGAGGCTCAGAGGGTG GGGGCAGGTAACCAAATGAGTTTTTTGTCTTCACAGGTCAAACCTGCGAGGTTGACATCAATGAGTGTGTGAAAAGCCCATGTCGCCATGGGCCTC CTGCCAGAACACCAATGGCAGCTACCGCTGCCTCTGCCAGGCCGGCTATACAGGTCGCAACTGTGAGAGTGACARCGAATGACTGCCGCCCCAGTAA GTGGTACCCAGCTCTGTCCATCCTATGTTTGGGTGCCTCTGTTCCTAAGCACACATGACAGGGAGCTGCTGAGAGTCTGAGGTGGAAAATAGCCCTG GTGCCCGGCAGTCATGAAGOACTGTGGATAGCTGTGCCCTCAGCTTAGTCCACTTGCCTGTGCCTTAAAAAGAGACAGGCCAGAGGCTAGACAGGCC AGGAGGAGGCTGTTGAGCATCAGTGTGTGCTTCTCACGGGCTTTGCTGCTAGATTTCCCAGCCCAGTTGAGTGATATGGAGCAGAGGCACCAGGCAC TTCAAATGATGGCATGGGGCCTAGTTGTATTCAACCTTGACACTCGGCCCTTGTCAGGACCCATTGAGTTGTGTAGGGCTTTAGAGATGCCCTGCA TCCTGAGTCAAAGCTAAAGGCAGAGAGAGATTGAGGGAGGTTCTGCCTGGCACCATCAGTGTGTGTGTAGGGGAATGGGCTTCCCTATGACTGCCTT GGGCCTGAGGGAAAAAGTGTATGCGGAGCAGATTCCAGGCTCAGTGCTGGGATGGGCCCCTGTTGACTACTGTCATCAAGGCTTGCTGTGAGCACTT GCCACCCCATACCACCTTCTCAGCATCAGGTCCCCGAAGCATGGCCAGTGGCCACCTAAGGCTCATCTTTCTGTCCCTCCAGACCCGTGTCACAATG GGGGTTCCTGCACCGATGGCATCAACACAGCCTTCTGCGACTGCCTGCCCGGCTTCCAGGGTGCCTTCTGTGAGGAGGACATCAATGAATGTGCCAG CAATCCCTGCCAAAATGGTGCCAATTGCACTGACTGTGTGGACAGCTACACATGTACCTGCCCCGTGGGCTTCAATGGCATCCACTGCGAGAACAAC ACACCTGACTGTACTGAGAGGTGGGTCCCAGCCTCAGCTGAGACAGGGAAAGAAATGGACTGTGGAAGACACAAAGTCTTGACAGCATGGCATCTCA AGCTGGTGTCTTGCCCAGACCCAGTGGGCATACAGCACTAATTGAACTGAATCCAGCGTTGTTCATTGTGTTGCAGTATCCCTCCTAAAGGGGCCTT TGTGACCTCCAGTGACTTAGACAAGGAGTTTGTGCAQAGGAATTGGGGAACTAGCCTCCTATCAAACAAGAGCTTTGTAATCTGTCTTAGTTCCC CTTTTGCCCTGGTTGCCAGGAAGCTTAGAGTTAAATCAATCTCAAGCCTGGITTGTGATGCGCTTCCTATAGTGTTCCTATTTTGCCCTTGATTTTG TTTTTCTCAACCACCACGTGTCTATATGCTATAATCTCTGCTCGTGATTTGGGTATTGTGGCCAGGTAGGCATGGAGTTGTCTCTCCTGGCAAGG ACCTTAGGGAACTCCTCACTCTTCCCTGCTTCTCATCTGCCTCTAGCTCCTGCTTCAATGGTGGTACCTGTGTGGATGGTATCAACTCCTTCACCTG TCTGTGTCCACCTGGCTTCACGGGCAGCTACTGTCAGTATGATGTCAATGAGTGTGATTCACGGCCCTGTCTGCACGGTGGTACCTGCCAAGACAGC TATGGTACTTATAAGTGTACCTGCCCACAGGGCTACACTGGTCTCAACTGCCAGGTGAGCTGAGGTTACAGGGTATGACCCAGAAGGCCTAGGGCTC TCCAGTGCCCATTGCCCAGCCCTGGGCCACACTACCTTCAGAGGGCCAGGGACACAGAAGCAGAGAGGCTCCCTGGTGTCATCATTGGTTGATGAGC CAGAATGAACCCACATCCTCTGGGAAAATGCCAAGTTGGGTGCTTCTGAGGGAGACAGGTGGGCATGGGTGCCAGCCAGGCTCTTCTGTGGAGTGCA TTATGTGGCCATCTGTCTGAAGCAGCCTGGGGCAGTGCTCACTTCTGGAGGAGGATGTCCAAGGGGAGGTAGCCAGTGGGTTGTGGAGAGCCTTGAA AGAGAGCAAGGAAGACGTGGAGCCCAGGCCTATGTTGTTCGGAGGGCGGGCAGTGTTTGTGAGTCCTGTGCCTGGGATTTCTTAGGTGATAITCTTT CTGAGATGGTGGGGGTGGGGGTGGGGAAGTCAGAGCATAAAATGCCTTATTCCAGTGGCGCTCAGCCTGTGGGTCATGACCCCAATAGGGGTCATAT ATCAGATATCCTGCATATTTTTGCTACATGACAGTAGCAAAATTACAGTTATGAAGAAGCAATGAAATAATTTTATGGTTGGAGGTCACCACAACAC GAGGAACTATATTAAAAGACTGCAGCATTAGGAAGGCTGAGAACTGCTGTGCTTCTCAGAGCCAGCCAGGACCAGGGCAGGAGGGTGCCCTAGCAGT CAGAGTTGGTCAGGGAGAAGCTAACCAGCGCCTGTCTCCTCAGAACCTTGTGCGCTGGTGCGACTCGGCTCCCTGCAAGAATGGTGGCAGGTGCTGG CAGACCAACACGCAGTACCACTGTGAGTGCCGCAGCGGCTGGACTGGCGTCAACTGCGACGTGCTCAGTGTGTCCTGTGAGGTGGCTGCACAGAAGC GAGGTAACCAACCGGCCGGGCCCACCTGTCCTTGCTCAGGCTCAGCTTAGGCCAGGAGTGCCCCGGTGCCTGCCAGGTCAGGTGACAATGGGCAGTA GTCCCGAGAATCGGAGCCCAGGCCTCAGCTCCTTCCCGTCTTGTCCCCACAGGCATTGACGTCACTCTCCTGTGCCAGCATGGAGGGCTCTGTGTGG ATGAGGGAGATAAACATTACTGCCACTGCCAGGCAGGCTACACGGACAGCTACTGTGAGGACGAGGTGGACGAGTGCTCACCTAACCCCTGCCAGAA TGGAGCTACCTGCACTGACTATCTCGGCGGCTTTTCCTGCAAGGTGGGGCCGTCATGGGGTGGCGGGGAGGGTATCAGCGTGAGTGTTGCTGCAGG GGAGGGCTTTTGACTGGGAGCTAGTGCATCATGGCAGACTGAGCACATACCTGTGCAGGATCCGGTCACATTACAGATGTGCTGAAGGAGGAGAACT ATGCCAAGCAGTGGCTTAGGGCACCCCTTTCCTATATGGTTTCATGGTACCTAATACCTGCTCCAAGACCTCATCCCTGGGGGACCAGGTGTTGCCC CACACACACACACCTTGGACACTTATTTTAACTTACTGGGGTCTACTGGGTGGAGCCCTCGCTGCAGGGTGGGACAGTGTAGTCTAACTGGGTATAT GGCCTGCATGGCAAGTGGAGGACATGATACCACAACCCCAGCTAAGCTGTGACCTGTGCCATTTCTACAGTGTGTGGCTGGCTACCATGGGTCTAAC TGCTCCGAGGAGATCAACGAGTGCCTGTCCCAGCCCTGCCAGAATGGGGGTACCTGCATTGATCTGACCAACTCCTACAAGTGTTCCTGCCCCCGGG GGACACAGGGTAAGGGTAGGGACCTGGATGATGGGCAGGATCCAGCCAGAGATCACTCAGGTGATTGAGAGCTGACCACGGAATAGGAATCTCAGAA GGGAGGTGGGCTCCAGTGGCACTGTGCTGCCTCCCCCGGGCCCCAGGTCCTAACTGATTTCTGGACTGGGCTGCACAGGACAGAGCACAGTCAGCAT CATCCGACGGTGTCTCTGGTCACTCTGCAGGTGTACACTGTGAGATCAATGTTGATGACTGCCATCCCCCCCTTGACCCTGCCTCCCGAAGCCCCAA GTGCTTCAACAATGGCACCTGTGTGGACCAGGTGGGTGGCTATACCTGCACCTGCCCACCAGGCTTCGTCGGGGAGCGGTGTGAGGGTGATGTCAAT GAATGTCTCTCCAACCCCTGTGACCCACGTGGCACCCAGAACTGTGTGCAGCGTGTTAATGACTTCCACTGCGAGTGCCGGGCTGGCCACACTGGTG CGTGCCTTGGGCAGGTGGGTCGAACGGGTGGGTGGGCAGGGTOACAGGGATGGCTCCTTACTGTCCCTTCTTCACACAGGACGCCGCTGTGAGTCA GTCATCAATGGCTGCAGGGGCAAACCTTGCAAGAATGGGGGTGTCTGTGCCGTGGCCTCCAACACCGCCCGTGGATTCATCTGTAGGTGCCCTGCGG TAGGTGTCCCTGGCCCTGTGCGGCTGCAAGGGTGCCAGGTCTGAGGGTGCCTGAACCCTGACCGACTCTTATGGTGGATCTGTCCTCCACCCACCCT CACTGTGAATAGTCAGCCTGAAGACCTCTAGCAGAGGCTAGGGTCCAAGCCACATGCTTCCTCGTGTCCATTCCCCAGCTCGTTTTTTAAACCCGAG CGGGCACGATCCATACATGCCTTGCTCCCAGTGCTCTGCAGCCTCAGGCTGAAAGATTGCCTTGTATTTGAGGTACCTTAGGCTTCACAACAAGACC CTGTTTAAAAAGTTTATTTCCTGCTGTGCTATGTTGGGAACCTCACACATGCTGGGCAAGTGTTTTGCCACTGTGTCTTAGCCCAATTTTTTAAATA GATGTTTATTTTAGAGCGGTTTTAGGTTTGCATGAGAACTTAGCAAGAGGGCCAGGTCCCCACCCTGCAGGCCGTTCCCTATGTTTGCTGCCTTGCG TGGAAGGTGTTGAGCTGGCACTAATATGCAGTATTTGCTCTTGGGTGTTGACATCCAGGGATCTGTACACATACAATGTACCAGCATCAGCCTTGGG TTTCATGGCTCTAAAAACTCCTAGGGTTCTCCCCATTCACCTATCCCTCCAGTTTGAAGCCCTTGGCAACCCTGACCATCCTATGGTGAGATGTTTC AAGGGTCTTGTTATTGGGGCAAGGCCATAGACACCTTTCACAGGCCACAGACTGGGGCCAGGTCTTTGCTGGGGTGTGCATGGTGTCCCTGATTGAA TGCACCATCCTCTCTCCACCACAGGGCTTCGAGGGTGCCACATGTGAGAATGATGCCCGCACTTGTGGCAGCTTACGCTGCCTCAACGGTGGTACAT GCATCTCGGGCCCACGTAGTCCCACCTGCCTATGCCTGGGATCCTTCACCGGCCCTGAGTGCCAGTTCCCAGCCAGCAGCCCCTGTGTGGGTAGCAA CCCCTGCTACAATCAGGGCACCTGTGAGCCCACATCCGAGAACCCTTTCTACCGCTGTCTATGCCCTGCCA.AATTCAACGGGCTACTGTGCCACATC CTGGACTACAGCTTCACAGGTGGCGCTGGGCGCGACATTCCCCCACCGCAGATTGAGGAGGCCTGTGAGCTGCCTGAGTGCCAGGTGGATGCAGGCA ATAAGGTCTGCAACCTGCAGTGTAATAATCACGCATGTGGCGGGATGGTGGCGACTGCTCCCTCAACTTCAATGACCCCTGGAAGAACTGCACGCA GTCTCTACAGTGCTGGAAGTATTTTAGCGACGGCCACTGTGACAGCCAGTGCAACTCGGCCGGCTGCCTCTTTGATGGCTTCGACTGCCAGCTCACC GAGGGACAGTGCAAGTAAGTAAGGCTGAGTTTCTTTAGAGTCCCAGGGCTCAGGATGCTACGGGAGGACCTAACCAAAcACCAGGCTCCTGAAGCCA ATGTCTATCCCTGCCCATTGCGAGTCGCCAAGCACATTTCCCAGATCTGGCCTATTCAAGGTATGGGTTTGAGGTCCACAGGCTGGGATGGGACTGA GTGCATCCTATACCTCCTCAGCCCCCTGTATGACCAGTACTGCAAGGACCACTTCAGTGATGGCCACTGCGACCAGGGCTGTAACAGTGCCGAATGT GAGTGGGATGGCCTAGACTGTGCTGAGCATGTACCCGAGCGGCTGGCAGCCGGCACCCTGGTGCTGQTGGTGCTGCTTCCACCCGACCAGCTACGGA ACAACTCCTTCCACTTTCTGCGGGAGCTCAGCCACGTGCTGCACACCAACGTGGTCTTCAAGCGTGATGCGCAAGGCCAGCAGATGATCTTCCCGTA CTATGGCCACGAGGAAGAGCTGCGCAAGCACCCAATCAAGCGCTCTACAGTGGGTTGGGCCACCTCTTCACTGCTTCCTGGTACCAGTGGTGGGCGC CAGCGCAGGGAGCTGGACCCCATGGACATCCGTGGGTGAGTGCTCCAGCTCCTGCTGTTGTGGGCTOTTTCCCAGTGTGTCCCTGGGTTCTCTAACC AGCTTAACCCTGGAGGTGTAACCTCAGGGGAGGTAGTATTCACCTTATTTTATAGTCAGAAAGCACCTGGGATGAAGAGGGCATCCCTCTGATGAGG ACTTGGCAGGCCTCAGGGTTTGCCCAGATGTGATTTTCAGGCCCCACTGTGThCCAGGTGTTGGAGACCAAGCTGATTAAAGCCTCCAGGGTGTCCC CTGGGGCTAAGTCATCCTAGACCAATCCTGACCCTCAGTCACTACAGCCCTTATCCCTACTACAGAGGAGGCAGTGAGGGGTACAGAAGGGCACTGT TGCTGAGCCTGGAAGGCTGAGGAGCCGAGGGAGGCACAAATAAGAGCATCTCCTGGATGCTGCACAGAGCCATCTGGGGATGGGCAGGGAAGCACCA GCCAGGCATTTGGAGGTTCCAGGAGCCTTCGCTGTTGGGCATCTGCCTGGTGGACCTCAGTGTCTCCTGACCCCAGTGGTTCCTGGTCCTGGTTTTT CTTGTCGTGGGACTGTGGTGAAGGTCAGAATTAATTGTTTCCTGGAGGCTGTTAGAATCCTGTTTCTGAGAGGCCAGTGACTGAGAGTTGGTGACT TGGCTGGCATGAGAGAGCTGACTCTCTGGCATCTGAGCCTGCTGTCACCTCAAGCTACACCATAGGGAGTCACAACTGCATCCTTGCAGTTCTGTTGG GGCCCAGGCACTGCTCTCAAGAGGGCATTGGATGCCTAAAGACTATTCTTTGAAGTAAGGAAAAAGGGGTGCTGTGCACCTAAGGGGCAAGGCTAGA CAGTGGAATGACCCCCGCTGAGTGCTAAACACTGGGGCAGCAGGGAGAGTGTCCCATTGCGGGGCTGTCGTCTGATAAGCCCTGTGGGTCAGGGTGA TGGGCTAGGGAGTCAGAGCTGGTGTGTAGGCAGTGTACTGGGGTGTATCTAATCTCACTGTGCCATGTGTGTTCTCAGCTCCATTGTCTACCTGGAG ATCGACACCGGCAATGTGTGCAGTCATCCTCGCAGTGCTTCCAGAGTGCCACCGATGTGGCTGCCTTCCTAGGTGCTCTCTTGCGTCACTTGGCAGCC TCAATATTCCTTACAAGATTGAGGCCGTGAAGAGTGAGTAATCAGGGGCTGGAGGGATGGCTCGGTGGTTAAGAGCACTGGCTGCTCTTGCAGAGGA CAAGGGTTCAAATCCCAGCACCCACGCAGCATCTTATAACTATGTGTAACTCTAATTCCAGGGCATCCAACACTTTCTGACCTCTGCAGGCACCAGG CATGCACAGGGTCCTGAGTACAACAGCAGGCAAAACACCCATACACATTACATATTTTTTAAATGAGTTCCCTACCCCGACCAGCCCTGCCTCTTCAG GGATGGGTTCATTGGGTGGCGGGTCACAGGCAGGCGGTCTCTCACTCCTTGTGCCAGCTGCCATTCCCAGCTCAGGAAGTGCTTTTCTGGAATTTTT TTCCAAGGCCTTCCCTCCCTGTGGCTAGTGGGAGCCGTAAGTAAAAGCTGTCCCCTAAGATGTATACATATACCAGAAAGTATGGAGGAGTCTTTCT TCTCTCCTCATTCTTTACCCCTGATTTTTCTTTGTTGGATATTATTTCAAAATCATTACTAGAGTTTTTTTGTGTGTGTTATTTTTTTTAAGAGAGA GAGAGAATTGATCGGTGTCATGTGAAGTGTTGAAGTTTGTATCTTGAAAATCCCCCTAAATCCTAACAGTCTTAACAGCTCAATGCGAGCGCAGTGATT TGAAGTTCGCTAATCCTTCCTTCTCGAAAGGGGAGAAGTGAGCACTGTCTCCAGACAGATCAGCTGGTGCAGGAGAGAATTTAGCGATAGTTTGCAAT TCTGATTAATCACGTAGAAAATGACCTTATTTTGGGGGGTGGGATGGAGGAGAGTGGGTGAGGAGGCACCGGCCGTGGAGCCAGTCCTCCGCCCCCC GCCAGCCCACAGCATCACCACGCCTGACGAGGGGTGCTTGCCTGCCGCCCCTGCCCGCAGGTGAGCCGGTGGAGCCTCCGCTGCCCTCGCAGCTGCA CCTCATGTACGTGGCAGCGGCCGCCTTCGTGCTCCTGTTCTTTGTGGGCTGTGGGGTGCTGCTGTCCCGCAAGCGCCGGCGGCAGCATGGCCAGCTC TGGTTCCCTGAGGGTTTCAAAGTGTCAGAGGCCAGCAAGAAGAAGCGGAGAGAGCCCCTCGGCGAGGACTCAGTCGGCCTCAAGTGAGTGGACACTG CTCCCACTGTGTGTGGGTGAGTGAGTGGCAGGGTTGGTGGGGGTGCTTAGCTCCAGAAGGCCCATGGGCCCATCCATCCCTGTCCGTTACCCTAAGC CCTTCTGCATGTAGAGGATGCCCATATGAGCTGTGGCTTCAGGGCATCTCCTGGAGTACCTGCTCAGTCTCCCTACCCCCATACCCAGGCCCCTGAA GAATGCCTCAGATGGTGCTCTGMGGACGACAATCAGAACGACTGGGGAQACGAAGACCTGGAGACCAAGAAGTTCCGGGTGAGTCCCGCAGGCTCC CAAGCCCCCCCTGGGTGGCACCTCCTGCCTTGGCCCCAAGTGATGAGGCTCTGCTTACTCTGTCCACACTCAGTTTGAGGAGCCAGTAGTTCTCCCT GACCTGAGTGATCAGACTGACCACAGGCAGTGGACCCAGCAGCACCTGGACGCTGCTGACCTGCGCATGTCTGCCATGGCCCCAACACCGCCTCAGG GGGAGGTGGATGCTGACTGCATGGATGTCAATGTTCGAGGACCAGGTAAGGCCACTGGAGACACATGCACACATTCCCTAGCATAGACTTAAGAGGC CAGTAGGACTTGAGGAGGGCTGGGTCACTGAAGGGCTCTGCCAGAGCAGCATCCTGCCCTGAGCTGATCGTCTGGCTCCTCCTGCCCACACAGTATA CTTTTTCATGAAATGCTGCTTTGCAATAGTCAAAGTGTTAATTTTTTITTTTTTTTTTGGTCTCAGTTTTTAGTATGCTGGGATTATAGGTGTGTCC CCATGCCCAGCTAAAGTGTTGACTTTTAAAATTATATGCATATAGGTGTATATAAAGATATCTTTTATTTTATGTGCATGGTTCTGCCTACATATAT GTCTGTGTAGTGTTTAGATACCCAGTGCCTGTGGGGAGCCTGAAGAGGCCATTGGATCCCCTGAAGCTGCAGTTACAGATGGTAGTGAGCAGCTATA TGGGTACTAGGGATTGAACTCAGGTCCTCTGGAAGAGAAGCCAGTGCTCTTAACCACTGAGCCATC1CTGCAGCCCTTATTTTATGTTTTAAAGCAT TTCTTCATTTGAGTGTAAGGGGCACACATGTGCCATAGTACACACGTGGAGGTCAGAGGACTACTTGTATGAGTGTGGGTTCTCTCCTTCTACCATG TTGGTCCCAGAGTGCCTTCCAGGGAGGCAGCACTGCATCCCTGGGGACTTCATCCGGGGTCCCTTAAACTGCAGGACTGCCTGCCAGGGCTATGGTT GAATGTTGACCCTCCCTGAGGCTGACACCATCCTTCCCACACCTACCCTTGTTTCTGTCCTCTCTGCAGATGGCTTCACACCCCTCATGATTGCCTC CTGCAGTGGAGGGGGCCTTGAGACAGGCAACAGTGAAGAAGAAGAAGATGCACCTGCTGTCATCTCTGACTTCATCTACCAGGGCGCCAGCTTGCAC AACCAGACAGACCGCACCGGGGAGACCGCCTTGCACTTGGCTGCCCGATACTCTCGTTCAGATGCTGCAAAGCGCTTGCTGGAGGCCAGTGCAGATG CCAACATCCAGGACAACATGGGCCGTACTCCGTTACATGCAGCAGTTTCTGCAGATGCTCAGGGTGTCTTCCAGGTACGCAGCACTGCATCCTTGGA GCCAGTGACCTCATCAGGTCTGACTGGCATGGACCCTGCAATCTCTAATTCCAAGTGTGACTGGGCAGGGAAACTTGGCACCTCCACACTGCATTTT GAAGGAAGTCCAGGTACAAAGGGCATCAAGTCCCACCTGTGTTCTCTGAGCAGGCTGGCTGAAGGTGGTCTTGCGGAACCTACAGGGTGAGGCAGGG CCTCCTTACTCTCAGTAAAACCCTCCCAATCTCAAGGCTATGGCCTTGACTTGAGGTCTCCACCTCCGTGCTAAAACCTTTGCAGACTAACCCTACC CCATTCAGCTGTGGCTGCAGGCATAGCCCATGGCGGCAGAAAGAGAGCTTTAGAGGCTGCTGGTCCTGGCCTGCAAAGCTATCTCCTGGCTTTGCCT AGAAGCCTGGAGCCAGCCTGGGTGGATTTAAGGATTTAGCTGOCTGGGTCTGCAGGGACCAACCCTAGTAGTTGCTCCTGCATGTTGCCAGCCAGTG ACCCCTGCTACCAGACCTGTCCTCTAGGCGGCCCTGGAGCAAACTCCAATGGGGAATAGACCAGGCATCAAAAAGCTTGTCATTTAATCATTTCTTA ACTTGAACCACACTTTGTCGGTCTGTAGAAGAAATTAAACAAGACAGGGCAATGTACACCTTTTATCCCAGCACTCTAGAATCTGAGAGGATTGTGA GCATGAGGCTAGCCTGGTCTTCATAGAAAGACCCTATTTCAAAATAGCAAAGAGAGGTTGAGACCAGCCACAGGTTATGTTGACTGCCTGGTGTACA GCTCTCCACATGGCCTGCCTTGCTTGCATAGACAGATGTGTGTACGTTTTGTAGGAATCCAGGCAGTGCTGTGAATCCTTACCCAGGTCACCAACCC ACTCCCTCCTCTCACCTTAACAGTTCCAAGTACGGCTATGGGCCATGAGCGGGATTCCTAGCCTGGTTACTCTCCCCTCTCTCCCCCATGCTATGCA GTTTGATTTCCTCAACCTGGAGGTAGTTCTGGCAACCATAACCAAAAGATGAGGTCCCAGTAGATCCCCCACTGTCACTAGGGACTGGGTAAGAGCC CCAGCTCTTGCACATGGAATGTAGCTCCTGCCTTCCTCAGGGGCTCAGCTGAGCCCAGTCCAGGCATTGGTTTCTGGAGATACAGGCTTGCATTTAG ATCACCCTGCCTGAACCCATCCCTGCCTTCCAGATCCTGCTCCGGAACAGGGCCACAGATCTGGATGCCCGAATGCATGATGGCACAACTCCACTGA TCCTGGCTGCGCGCCTGGCCGTGGAGGGCATGCTGGAGGACCTCATCAACTCACATGCTGACGTCAATGCCGTGGATGACCTAGGTAGGCCCGAGCT ACAGCCCAGCTACCGAGGACATCAGCCAGTGCCTGGTCTGCTCAGCCCCAACCCACTCTCTCCTCTCTTTGCTTCCTTTCCAGGCAAGTCGGCTTTG CATTGGGCGGCCGCGGTGAACAATGTGGATGCTGCTGTTGTGCTCCTGAAGAACGGAGCCAACAAGGACATGCAGAACAACAAGGTAAGCAGACGGG CTGCTTAACCGCAGGCGCATGATGGGGACTCCGGGGCACCCAThCGTTGACCACTTAGAGGTTTAAGAGTGTCTGGGACAACAGCAGCCTAAAATAA CCCGTGCTCTTGOTGGAGAGGAGCTGAGGCGTAAGCAGCTGTCCCATGTCACGGTTACTTGAGCCTTGCCTTCTGTCCCCTTCTGTCQCTGGTGGCT GTGGTGACCCTAGGGGTTCAGGATTGGCCAAGGGGCAGGGATGGGGTGGCCCTGTCTCTTAAGGCCTGCAAGGCTTCTGGCTTGGTCCACCACTACC ATGCTCCCTCCTTTGGGATAAGAAAACTGCTGAGCTGGGCTGCGTGTCTQCACCTCGCCTCCCAGTGTCTCTGTTTGTGCAGGGCTAGTTGCTTCAT CAGGACTCTGCTTAGTTGCTCACAGGGCAGAGTTTGTGCCTCCCTTACCAGCTCCACTGCACGCTGGGAAATGGAGCAGGAGTCAGGTACCTGGAGT TGCTGTTGGGCACAGGTTCTCCACAGTCCAGGGTGGGCCAGTGGTTATAGAGAATCCAAGCCTGATAGACATTCTGTTGTGGTGTATGATTATGTCT GCTGGACAGAGCAGACCTGGAAGGAGCTGAGATGCCCTAGCCACTGGTGACCCTTTGGCATGGTAGTACCTTCCCCATGGCCATTCACTTGCCTTAA AGGTCCCTGAGTCCCAGGATTGCAGTACTTGTGCCTGCATTTTGGGGAGGAAGCAAAGGGCACACAGTTACATTCTGTTTTCGGCASTCTGACTCC ACACAGGGGAAGAAGCCCTATGTATTTATCCCACAGATCTCTGGGGTGTGAGGTGTTAAATCTAGGTTCTCTAAAAAAGAACTCGGGACCAGCCAT GTGTGCGTGCTAGCACCGAGAGCTGAGGCAGGACGATACTGAGTTCCAAGTACGGCTGTGGGCCCTGAGTGAGATTCCTAGCAACATAGGAAGGCC CCACTATAAATACTCTCTGAGCCTGGTGGTCTAGGATGCTTGGGTCTAGATAGATCTCTCCAGATAAGAGAAGAGAAAGAGGCAGCACCTGCTTCCC TAGCCCCTCCCCCCAGGCCATCCATCATCAATGACTCAGCAAATTCTACACCTGCCCGCTCCCTCATGTACCTCCTGTCCGTGTCCTACAGGAGGAG ACTCCCCTGTTCCTGGCCGCCCGTGAGGGCAGCTATGAGACTGCCAAGTGTTGCTGGACCACTTTGCCAACCGGGACATCACGGATCACATGGACC GATTGCCGCGGOACATCGCACAGGAGCGTATGCACCACGATATCGTGCGGCTTTTGGATGAGTACAACCTGGTGCGCAGCCCACAGCTGCATGGCAC TGCCCTGGGTGGCACACCCACTCTGTCTCCCACACTCTGCTCGCCCMTGGCTACCTGGGCAATCTCAAGTCTGCCACACAGGGCAAGAAGGCCCGC AAGCCCCAGCACCAAAGGGCTGGCTTGTGGTAGCAAGGAAGCTAAGGACCTCAAGGCACGGAGGAAGAAGTCCCAGGATGGCAAGGGCTGCCTGTTGG ACAGCTCGAGCATGCTGTCGCCTGTGGACTCCCTCGAGTCACCCCATGGCTACTTGTCAGATGTGGCCTCGCCACCCCTCCTCCCCTCCCCATTCCA GCAGTCTCCATCCATGCCTCTCAGCCACCTGCCTGGTATGCCTGACACTCACCTGGGCATCAGCCACTTGAATGTGGCAGCCAAGCCTGAGATGGCA GCACTGGCTGGAGGTAGCCGGTTGCCTTTGAGCCACCCCCGOACGCCTCTCCCACCTGCCTGTAGCCTCCAGTGCCAGTCCAGTGCTGAGTACCA ATGGCACGGGGCTATGAATTTCACCGTGGGTGCACCGGCAAGCTTGAATGGCCAGTGTGAGTGGCTTCCCCGGCTCCAGAATGGCATGGTGCCCAG CCAGTACAACCCACTACGGCCGGGTGTGACGCCGGGCACACACTGAGCACACAGCAGCTGGCCTCCAGCATAGCATGATGGGGCCACTACACAGCAGC CTCTCCACCAATACCTTGTCCCCGATTATTTACCAGGGCCTGCCCAACACACGGCTGGCAACACAGCCTCACCTGGTGCAGACCCAGCAGGTGCAGC CACAGAACTTACAGCTCCAGCCTCAGAACCTGCAGCCACCATCACAGCCACACCTCAGTGTGAGCTCGGCAGCCAATGGGCACCTGGGCCGGAGCTT CTTGAGTGGGGAGCCCAGTCAGGCAGATGTACAACCGCTGGGCCCCAGCAGTCTGCCTGCACACCATTCTGCCCCAGGAAAGCCAGGCCCTGCCC ACATCACTGCCATCCTCCATGGTCCCACCCATGACCACTACCCAGTTCCTGACCCCTCCCCTCCGCAGTTACTCCTCCTCCCCTGTGGACAACA CCCCCAGCCACCAGCTGCAGGTGCCAGAGCACCCCTTCCTCACCCCATCCCCTGAGTCCCCTGACCAGTGGTCCAGCTCCTCCCCGCATTCCAACAT CTCTGATTGGTCCGAGGGCATCTCCAGCCCGCCCACCACCATGCCGTCCCAGATCACCCACATTCCAGAGGCATTTAAATAAACAGAGATGTGGGAT GCAGGACCCCAGOTTCCGTTCCCAAGCCCTGTTGGGAGTCCTTTCCAGTGCTTCAGGATGCTGGGGCGACCAAAGGAGCCTTTTAAAAAATGTTTTT ATACAAAATAAGAGGACAAGAATTTCCAT1TTTTTTTTTTAGTATTTATTTATGTACTTTTATTTTCCACAGAAACACTGCCTTTTTATTTATATGT ATTGTTTTCTATGGCACTAGGGAAAAACATATCTGTTCCAAGAAAATAAACTAGTTCTCAGAGCCTTGATTTTCCTGGTCAGGGTGAAGTTCCCTGT GTGTCTGTAAAATATGAACAAGGATTCATGATTTGTAAATGCTGTTTATTTATTGATTGCTTCTTTCCAAAATCGAAAAGAAAGAAAAAAGAACGTG ACAGGAGAGGGAAGCTGGAAACTGCCATGGCCAGAATTGCCCCTCCCCCACACTCACTGCCCCTCCCCCCAGCGTCACCTGGGATTTGCAGATGTG TTTAGAAACACGCCCAGACCTTGAACCTTGGGTTCATGGATTAGTTTTGTATCTAAAACAGGAAACAAGTCAGATGATGTGGTTTGTACACTTTCTG TAACCACCAGTGTGGACTTGAAGAAGTGTCCTCAGCATGTGCAGAGTCTACTACCCAGTACCAGTCGTGAGTCTGCAGGCTCCAGTGTTCTGTAGTA TAGAGAAAACACTGCCTGGACTGTTCTGTGCATCCCTCCAAACAGCATCATCCAAATCCAACTGAGGACAGACGGACTGTCCCGGCCTGGGCCTGGG CTCCTAACACCTGACTGCCAAAGGGCTCCAATGTGCATTGTGGACTCGCCAGAGTAGCCTGCATTGAGACTCCAAGAAAACAGAAGCTATGTGGCCT CTGATCCCCAAACTGGCCTGGGTGGGGACATGCCTTGAGTGTGCTGGAATGTGGGTGGAGCCTGCTTCTGGGCCACCCCTCCTGGTTCAGGGCTGTG CTCACAGCAGATTCTTGCAGTATCAAGTATACGCCTGTGGCAGAATAAGTATCTGTAAATACATGTTTAAAGATGGATTTTGTTTAAAAAATCTAAA GGAACAAGTGTGTCGTGTGTCAAGCTGATGAGGACTGECAGACTGTGGCTTAGCTCAGTGTGACCCAGACCTTGTGACCTGTAGCTGCCGAACCAGT AGCTCCTAAGAGCACAACCCAGGATGGCCCATCTGCTGCCCACCAAGTCCCTTTCCAGCCACTGTGTGCTGGGGGCTTTCGGGGGCAGTTGCCCACC TCCTCAGGGAGCTCTTTCTGGCCTTTTGGGGGGCAGTGTCTGTGCCATGCCTAATAGATATGACCAGACGCATCCTAAGATGTTGATTCTTACTGT GTTGTATAAAATAAAGTGTAGTTTACAAAAAAAAGAAACGTAAAAAAAAAAAACTACATGCAAAACTGTAGGTAATGAAAATGATGTATTTTTTTCA TCTTTTTTTGTTAACTAATTTGCAATAAAAATGATACTGATGGTTGTCCACATTTTGCTAAACTTGGAGTGTGGTTTGGTTCACTTTTTGGGGAGTG TGACAGAGAAAGGGCCACCCAGCACTGAAATAACCAAATCCAAACCCTCTCTTACACAGAAATACAGAGGTTGCCATAAGGACACACCATTTTCAGA AGCTGCACAGCGCAGGGCATCAAGGTGGGAAGACAGTTTCCAAAAGAGTTGATGCAGTCCTCTCAGGGATGTGGATCTGATTGATGCCAGCTGTATT CCTGTGAGCAGCAGAGGAGTGAAGGCACCTTATGTTGTCATAGATGACTATCCTCTGAGCCCAGTAACCCCCAACCTCTTCAAATTCAGCCATGCCT TGCAAAAGGTCATCCCAGCTGTGCTTGTTGACTGCTTATAGACCCCCTCAAAGAGTTGGGAAGGTCATGGGACTCAAAGGACCCTTGCCTGATGATC CAGTCACTTTGTTGTATGCAGTCCTGCCCTAATTGTGCATGACCTCAGGGAGGTACTAGAGTATATAGTCTGGGAAGACTAGTGGAGAGACTCCATC TATGTGGCTGTGAGGAAAGCCTTATCCCTGCTGGGTAAATGTTGTATTAATATTCATTTAATAAAGGCTGGGCGTGGTGGCACACGCCTTTAATCCT AGCACTCAGGAGGCAGAGGCAGGTGGATTTATGAGTTCGAGGCCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTATACAGAGAAACCC TGTCTCGAAAACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTCATTTAATAAATCCTGGCAGCAGGTCACTATCCAACTCAATGGTTTATGAA AGACACACAACCTTTCTTTATATTTTATTATGTCTTATTCAGCACAATAGCTGGGTAGCTGCCTAGCCTCCATATTGCTAAGACTCTGTCTCCCCAT TCTGAATTCCTGCTTACTAATTCTATGTTCTATCGTGGCTGATCTAGACCAAGTTGGGCAGCCTTATAGGCCATGCTCTCCCAGCTCCTTCAGGTGG TAGCCTTGCCTCTCTGTCCTGCACTCTTCCCAGGCATGGCATCTCTCCTCTCCCCAACTCTCCCTTCTCCCACTGCCTCAAGTCTCAAGCCCAGGAG TCCTAAACGGTCCACCTTGTCTGTCCTCCCCAGCTACTGGCTATTGGTATCTTTATTTACCAATCAGAACCCACTGGGGACAGGTTCCCAAAAGCTA TGTGTAGACCTTCCTGTGCAGTTCGGGGGAACATTAACATTTGTAATACAAACAGCTACAAGTAAAGAGTTCCAATGTGGACTCAGTAAGTAACCCT TTACCTATGTTCTGCTCTTGTCAGCGCTGCAAATCCATTGGTGCCCTAGTCAGCTTTGGTGCCTAGGACCTTAGGAGGAGGGTTAAGTGTTGTCTCT TCCTGGGAAGGAATTTTAGCAACACTCATCTAGTCCGAGAGCCCAGCAGGTACAAAGGCATCTTAGCCCTAAGAAGAAATCATAATAGCACAGGTGT GGATCTCCCTTGGCCTGCTGTACTGGCTAGTTTTGTGTCAACTTGACACAGCTGGAGTTATCACAAAGAAAGGAGTTTCAGTTGGGGAAATGCCTCC ACGAGATCCAGCTGTAAGGCATTTTCTCTTAGTGATCAAGGGGGGAAGGGCCCTTTGTGGGTGGTACCATCTCTGGGCTGGTAGTCTTGGGTTCTAT AAGAGAGCAAGCTGAGCAAGCCAGGGGAACCAAGCCAGTAAAGAACATCCCTCCATQGCCTCTGCATCAGTTCCTGCTCCCTGACCTGCTTGAGTTC CAGTCCTGACTTCCTTGGTGATGAACAGCAGTATGGAAGTGTAAGCCGAATAAACCCTTTCCTCCCCAACTTGTTTCTTGCTCATGATGTTTGTGCA GGAATAGAAACCCTGACTAAGACACCTGCCTAGGCCTCTCCATTTGGCCCACACCTTGGAGCACAGCAGGAGTCTCTAACCAAAGTGACAATGGGGA ATGTGATGCCCTCTCTGAGCCTGACATCTGAGGACAGTGTGAATCCATCAAGTTCAGATGTCTTGCCCCGGCTCAGTGTTGCACACTGTGAAAGCG GAGGGGGCCCAGGGGCCCAGAAGGGGTGCTCACACACAGAATTGTGATAACTTGTCTCATTCTTGCCCTCAAGGGGAAGGTCGGAGCCTGAATTCTG CCCGGAGAACTAGCATCTCCAAAATTCCATCCGGAATGGAAATGTCAGCTCGGAAAGGGCTTAGCAGGCTCATATGCCTGGGTGTTCTCTAGAGCAT CATCCACAATGGCATGTGCAGCCCAGGGTTCACAACTGATGGCTGGACCACTGAGAACACATCTGGACTGGGTTCGGGGTGAAAAACATTGATGTTT GCAGATCAAAGCAAGGGCCTACCCATGTGGGCAAATCTTCTCCAGTGAGAGACCAAACAACAAAAGGTCAGGGAAGAGGGGATGGATCCTGCCTACT GCGGCAGAACATGAATCCTCTCCCCTCCAGGCTCCCACGGAAAGATTGCCTGTTCTTGGGTCTCCAGCTTGCCAGGTACAGCTCTGGGGACTTGCCA ACCCCACAACCTCTCTTTGTATCTACCCTAGTAAACATTCAGTGGAGTATTTTTCAGCCATTAGAAGGAACAAAGCTCTGAGACCTACTAACATGTG GGTGAGCTGCAGGAGGACACAGGGCTCGTGAAAGACATCTCAAAAATGACCACATGATTTCATCTTTATGAAATGTCCTCAGTAAGTAAAGCCACAA AGACAGAGAACAGAGTGGCCATTCCTGGGTCCAGGGAAATGGGTATGACTGACAATGCCTATACATTTGACTTTGCATGGATAGTCCAGCACTGTGT ACGTCTAAGGCAGAAGGCTGCATGGCACTGTGAAGGTCCCAGACCCGTCAATGCTACAATTCCACAATCTGTGAGTCTACTAAAACTAGCAAAAAAA AAAAAAAAAAAAAAATCCAAGCAAAATGGGAACTTTCAGAAATTTGTCCCATGGACACAACAAGTTCTCTTTTATTTTGTGACAGGATCTTGCTGGG TATCCCAGGTTGGCCTCAATCTCACCATCCTCCTGCCTCAATCTCCCAAGTGTTGGGATTCTAGGTGTGTACCACGCCACCCACTTAAACCTAGTAC TCTTAAGGAGCATCTATCTGCCCCTAAAAGCCACTGGAAATAAATAAAACATGTAAAACAATATTTTTAAAGGGCTAAAGATGTAGCCTAGTAGTAG AGGGTTTGTTTACTCTGTGCAAGGCTCTGGATTTCATCCCCAGGACCAATAAAGTAATCAATAAATTGGCTTGAGACAACCTTCAATAAATTCCTT GTTCTATGAACCTGAGCTCCTCATTTTGAGTCATGTAAAAAAGTTGGGTATGATCATGTGOTGTAATCCCAGCATCTGTGAGATGGGGAGGTAGAGA TCGGTAGAGTCCTACTTAGCTTTTGTCTAATCAGTGAGTCGCAGGTCCCAGTGAGAGACCTTGTCTCAAAAACTAAAAACAAAAAGGCCGAGGACTG GGGAGATGGCTCAGATAGTAAAAATTCCTACTGCACTAGCACAAAGACCTGAGTTTGGAATCTCCAGCATCCACATGCTGTCCTGGAATGACCATAC ATCTGTAATCCTGTGCTGGGGTGGGGAGGGAGACAAGATCCTGGAGCACCACTTGCCTAGCCAATGATCAATCAAGCACTAGGTCCAGTGAGAGAGA CCCTGCCCCAAAAACCAGGATGGAGTCAGGCATTGTGGCACATGTTTAACCCCAACATTCAGGAGACAGAGGCCCAGGGCTAAAATAGTCTCTGTCT CAAAAACAAACTAAAAAACCAAGCTGAGAATGAGAATGATACCTTCTGGCTTCCACATGCCATATATACATATACATGCTCACACGCACAGGCACAC ACATATGCACAGTGTAAGGACTAAATTGGGCACCCAGCAGCTAGACAGCCCAGAGAGAATAGAGTCTTGCAGCCTCAGCCTTCCTTTGTTTAGGG GGGATTACAGGACAGTGGGCCCTGCTGTCTCTCAACAGAAATACTCCAGGACCAAATCCCAAGCAGACAGAGGTATGGAGATGAGCTCTGTGTCATA CACACACTGAAGATGGTCATATACAGACATGGGAGCAGAGGCAACTGAGTGGTCTTGGAGCAACTTGCCCTGTGGTACCCGGTCACAGACCTCCAGG ACAAGGAAATTCCTGTGAAATCCAACTGGTGTGGGGCTGTTTACACAGCAACCTTGGATAGATTGATCCAGTCTCGGGCTGAGGTGATGTCTTGGATG CCGAAATCTCTCAGGGACACAGGCCAGTTCAGTTCCCTAGGTACTGCCTTTCCCCCACAATGAAATGCCCTCTGTGCTGGCTAGCTGTAACACATCA ACTTGACACACAAACTACAGAGTTATCTGAGAGGAAGAAACCATAATTGAGAAAATGCCACTGTAAGATCTGGCTGTAAGACATTTTCTTAATTAGT GATTGATGGAGGAGGGCCAGCTTATGGTCCTGAGTTCTATAAGAAAGTAGGCTGAGCAAGCCATGGGAAACAAGCCAATAAGCAGCACCCCTCCATG ACCTCTGTCTGTATCAGCTTCTGCCTCTAGGATCCTGCCCTGAGTTCCTGTCCTGACTTTCTTCAGTGATGAACAGTGCTGTCAAAGTGTAAGCCTA AGAACTCCTTTCCCCTCCAACTTGTTTTTTGGTCGTTGTTTCATCACAGCAATAAAAACCTTAACTAAGACACCACCACTCCCCAGGGATCTGCCAT CTTGTAATGTTTTTGTTTGTTTTCAATTAGAAGAATAGTTATTATGTATATACTACTAGAGGGCAGTGAGTTAGGCAGTAGTGAGTAAGCAGGGGC ACACTACGTCCTCTGGCTGGCTGAACCTTGTGATCCTTCTGCCTCAGCCTCCTGAGTTCTAGGATTGCAGGTATGCCCCACCAGGCTTGACTTTAAG TCCTACTTTTCAACATTCAAGTATGTAAGTAGTTCCAGACAAGTATGGTAAATCCAACACTCTAGAGGCTGAGGCAGGAGGACTGCCATAAGTTCAA GGCCAGCCTGAGTTATATAGCTAACTTCTGTTTCAAAAATAACAAAAGCAGATATAAATAACCCGAGAACAGCCTGGTGGTGGTGTTGCACACCCTT AATCCCAGCACTCAGGAGGCAGGCGGAGGTAAATTTCTTGAGTTCCAGGCCAGCCTGGTCTACAGAGTGAGTTTCAGGACAGCCAGGGCTACAAGGA GAAACCCTGTCTCAAAAAACTGAAACCAAACCAAATAGCAACAAAAACAAACCCAAGAACTAGTTCTCTTCCTGTCCCAAGTGTCCTTCGCTCCACT GTCTGTGTATATCTTCAGTATGAGAGAGAAGGGCTTCCTTAGCCTCCTGGGGTCATTCAGAGAAGCCCA2TCCAATAGAAATAAGACGGAAACCACA TAGGTCATTCAAAGTACTTCATAACCCTTAAAAAGGTCAAAGGAGCAGGTGAATTTATTTCAATACTACATCTTGGTTCGTCCAATGAAACCACAGT TACCACTTAACTAGCAGTCAACACAAGCGAAGTATGAAAAGGACAGAGTTGACATTCTTTGTATTATTATTTGTATTTATTTGCTTATGTATATGTG TGCTAACACATGCCATACATGTAGAGGTCAGAGGACAAGTGATGAGAGCCAGTCTCTCCCTCTACCATGTGGGTCCTAGGGACTGAACCTGGGTTGT CCTCCTTGCAGCAGGCACCCTTACCCACTGTGCCAGCTCACCTGCATTATCACCATCTGCACTGGCCATGCTGAAGGTGCTTAGAGGCCACACATG GTCAAAATGTCATCCCAGACAGGCTAATCTCCACCAGCACAGATAAACAACCCATGGAGCCAGATGTAGTACTGGGAGCACTGGGGGGCGAAGGGGA GGACGGTAAAGGCAGGAGGTTCGAGTTCTAAGCCAGATCCTGTCTATAAAGATGTAAGCAAAGGAATAAAGAAGGTGAGGGGAGAGACTGCTATG CTGGTGTTGTTTCTTGTCAAAGGAGGCACCAAATGTGGCTCTGCATTGCTTTGTCCAGCACAAAGAGGGACCCAAGGGTATTAGTGCCATAAACCCA GCCAAAGCAGCAGGGTTATGCCTACAATCAAAAGTGATGGAGTGCTGCTGTCCTTCTGAGACTCCGGGAACCAGCCAGCCATGAGTCTTGCAAAGTT TGCTATCAGGGACACTCTATGGGGAGATTTTTACTATGTGACTCCAGACCCCACCCTGTGGAGCTGTGGAGACCCAGGCCAATCCTCAGCTGCATAC GAGTTAGGAAACAGGGCTCTTTTACTACAGTATCCTCAAGCCCGACTGAGCTATGTGTACTGTGGATTTCGAAAGGTTTGTGTGGAGCTTCTCCAGA GAATCCCTCTGTTTTGAAGATCAAGGACAGGGATGCTGCTCTCTCCACCTGCACTTTAAAGATGATGTGGTCCTGTCCTAATTCCTGACCACCCTCA CGGGTGGTGTTCTCATGGACTACCTGGCAGCTGTGGGATAGAAGGTCCCTAGAGTGTCCTCCTGTGTGAGGGGTGACOTCCAAGGTCTATGTGTGGA CAAGCCCAGCATACACAGTCACTGGTCACCACAAAOTCATTGAGAGATGGTGTCTTAGTTAGGGTTTTACTACTGTGAACAGATATTATGAGCAAGG CAACTCTTTTTTTTTTAAAGATTTATTTATTATTATATGTAAATACACTGTAGCTGTCTTCAGACATTCCATAGTAGGGCATCAGATCTCATTGTGG ATGGTTGTGACTACCATGTGGTTGCTGGGATTTGAACTCAGTACCTTTGGAAGAGCAGTCAGTGCTCTTACCCGCTGAGCCATCTCACTAGCCCTG ATCAAGGCAACTCTTATAAAAACAACATTTAATTGGGGCTGGCTTACAGGTTCTGAGGTTCAGTCCATTATCATCAAGGCAGGAACATGGCAGCATT CAGGCAGACATGGTACAGAAGGAGCTGAGAGTTCTACAACTTCATCTGAAGGCCACTAGGAGAAGGCCAOTGACTTCCAGGCAGCTAGGACAAGGGT ATTAAGGCCCACAACCACAGTGACACACCCACTCCAAAAAGGTCACACCTCCTAATAATGCCACTCCCTGGGCTGAGCATATATAAACCATCACAGA TGGCCAAGAATGGTTGCTTCAATGCTTTTATGTGCACATACCACCTAGAGTGTTCCACAAAGTTCAGGGTTCAGAGCTTTCACACAACTTTGACCTC AAGGCTTATTTTTAGATTCTAGTGCTTGTGAGATCCATTCTCTACAACACCATGCTATTTCTATGACTATTTCAAATACAAGACTGTGTTATGCCGG GTGTGGTGGTACATGCCTTTAATCCCAGCACTCAGGAGGCAGAGTCAGCCGGATTTCTGAGTTCGAGGTCAGCCTGGTCTACAAAGTGAGTTCCAGG ACTTCCAGGGCTACACAGAGAAACCCTGTCTCGAACCCCGAACCCCCCCTCCGCCCCCCAAAAAAGACGACTGTGTTCTGTTTCTCATGAGATTCTT CTGCATGGGGTGAGCATGCTTTCTACTGGAGCTGTGGACACTCTGGCACTCAGAAACAAGTCTGACCTAAGCTACTTATTTACTCCCCATCAATACA ATCTTCTTAAGCTGGAAAAGGGAAGGGGAGAGAAAAGGTCTCTGACCTTAGCCTCAGCAGGCCAGGTGGAAGGGGTGACACAGAACAAGGCCCTTTC CTCTACCTTGAAAGCAATGCCACAGGCTCCCACAAGGTTGAGGATTCTGTCTCTGACCTCAGAGCTTGGAAATCCATTGTCTTCTCTGACTCCAATG TGCTCAACTCAGAGAGCATTTATGCAGCACCTGCTATCTTTAGTAAGCCCACCCCCTCCAGGGAGTCCAGAAGTAAAGACTTCCCTCTGCGAGGGCT GCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGTTAGGGGGGTCTGCAGGGTATGCAACACCTGCACCTAACTCAAGTGAGATAGGATC TGGAAGGAGCCCTCAATGGATGGATAATTTGTAGGTAGATTTGTAGGTGGCTCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNNNNNNNNNNNNNNNMNNNNNNNNNNNNNNNNNNNNNNNMNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN MOUSE SEQUENCE-mRNA GTGGTGTGCGTCAACGTCCGATCCCCGCCGGCCACCCCAAGAGGCCGCCGCCGGGCTGCGGGCAGCTGGCGAGCAGGCATGCCACOGCTCCTGACGC CCCTTCTCTGCCTAACGCTGCTGCCCGCGCGCGCCGCAAGAGGCTTGAGATGCTCCCAGCCAAGTGGGACCTGCCTGAATGGAGGTAGGTGCGAAGT GGCCAGCGGCACTGAAGCCTGTGTTGCCAGCGGCAGCTTTGTGGGCCAACGATGCCAGGACCCCAATCCTTGCCTTCAGCACACGGTGTAAGAATGCT GGAACGTGCTATGTTGTGGACCATGGTGGCATCGTGGACTATGCCTGCAGCTGTCCCCTGGGTTTCTCTGGGCCCCTCTGCCTGACACCTCTGGACA AGCCCTGCCTGGCCAACCCCTGCCGCAATGGGGOCACCTGTGACCTGCTCACTCTCACAGAGTACAAGTGCCGCTGCTCTCCAGGGTGGTCAGGAAA ATCATGTCAGCAGGCTGACCCCTGTGCCTCCAACCCCTGTGCCAATGGTGGCCAGTGCCTGCCCTTTGAGTCTTCATACATCTGTCGCTGCCCGCCT GGCTTCCATGGCCCCACCTGCAGGCAAGATGTTAATGAGTGCAGCCAGAACCOTGGGCTGTGCCGCCATGGAGGCCACTGCCACAATGAGATCGGCT CCTATCGCTGTGCCTGCTGTGCCACCCATACTGGTCCCCACTGTGAACTGCCCTATGTGCCCTGCAGCCCCTCACCCTGCCAGAATGGAOCAACCTG CCGTCCTACAGGGGACACCACCCACGAGTGTGCCTGCTTGCCAGGTTTTGCTGGACAGAACTGTGAAGAAAATGTGGATGACTGTCCAGGAAACAAC TGCAAGAATGGGGGTGCCTGTGTGGACGGCGTGAATACCTACAATTGCCGCTGCCCACCGGAGGTGACGGGTCAGTACTGTACAGAGGATGTGGACG AATGTCAGCTCATOCCAAATGCCTGCCAGAATGCGGGAACCTGCCACAACACACACGGCGGCTACAACTGTGTGTGTGTCAATGGGTGGACTGGCGA GGACTGCAGTGAGAACATTGATGACTGTOCCAGTGCCGCCTGTTTCCAGGGTGCCACGTGCCACGACCGTGTGGCTTCCTTCTACTGCGAATGTCCG CATGGGCGCACAGGTCTGCTGTGCCACCTCAAGCATGCGTGCATCAGCAACCCCTGCAACGAGGGCTCCAACTGTGACACCAACCCTGTCAACGGCA AACGAATCTGCACCTGCCCCTCGGGGTACACAGGGCCAGCCTGCAGCCAGGACGTGGATGAGTGTGATCTGGGTGCCAACCGTTGTGAGCACGCAGG CAAATGCCTCAACACACTGGGTTCTTTTGAGTGCCAGTGTCTACAGGGCTACACGGGACCCGGCTGTGAGATTGATGTTAATGAGTGCATCTCCAAC CCATGTCAGAATGACGCCACTTGCCTGGACCAGATTGGGGAGTTCCAATGCATATGTATGCCAGGTTATGAAGGTGTATACTGTGAAATCAACACGG ATGAGTGCGCCAGCAGCCCCTGTCTGCACAATGGCCACTGCATGGACAAGATCCATGAGTTCCAATGTCAGTGCCCCAAAGGCTTCAACGGGCACCT GTGCCAGTATGATGTGGATGAGTGTGCCAGCACACCATGCAAGAACGGTGCCAAGTGCCTGGATGGGCCCAACACCTATACCTGCGTGTGTACAGAA GGTTACACAGGGACCCACTGCGAAGTGGACATTGACGAGTGTGACCCTGACCCCTGCCACTATGGTTCCTGTAAGGATGGTGTGGCCACCTTTACCT GCCTGTGCCAGCCAGGCTACACAGGCCATCACTGTGAGACCAACATCAATGAGTGCCACAGCCAACCGTGCCGCCATGGGGGCACCTGCCAGGACCG TGACAACTCCTACCTCTGCTTATGCCTCAAGGGAACCAAGGGCCCAACTGTGAGATCAACCTGGATGACTGCGCCAGCAACCCCTGTGACTCTGGC ACCTGTCTGGACAAGATTGATGGCTACGAATGTGCCTGTGAACCAGGCTACACAGGAAGCATGTGTAACGTCAACATTGACGAATGTGTCGGGCAGCC CCTGCCACAACGGGGGCACTTGTGAGGATGGCATCGCGGGCTTCACTTGCCGCTGCCCCGAGGGCTACCATGACCCCACGTGCCTGTCCGAGGTCAA CGAGTGCAACAGTAACCCCTGCATCCACGGAGCTTGCCGGGATGGCCTCAATGGGTACAAGTGTGACTGTGCCCCTGGGTGGAGTGGAACAAACTGT GACATCAACAACAACGAGTGTGAGTCCAACCCTTGTGTCAACGGTGGCACCTGCAAGGACATGACCAGTGGCTACGTATGCACCTGCCGAGAAGGCT TCAGTGGCCCTAATTGCCAGACCAACATCAACGAATGTGCCTCCAACCCCTGCCTGAACCAGGGACCTGCATTGATGATGTCGCTGGATACAAGTG CAACTGTCCTCTGCCATATACAGGAGCCACGTGTGAGGTGGTGTTGGCCCCATGTGCTACCAGCCCCTGCAAAAACAGCGGCGTATGCAAGGAGTCT GAAGACTATGAGAGTTTCTCCTGTGTCTGTCCCACAGGCTGGCAAGGTCAAACCTGCGAGGTTGACATCAATGAGTGTGTGAAAAGCCCATGTCGCC ATGGGGCCTCCTGCCAGAACACCATGGCAGCTACCGCTGCCTCTGCCAGGCCGGCTATACAGGTCGCAACTGTGAGAGTGACATCGATGACTGCCG CCCCAACCCGTGTCACAATGGGGGTTCCTGCACCGATGGCATCAACACAGCCTTCTGCGACTGCCTGCCCGGCTTCCAGGGTGCCTTCTGTGAGGAG GACATCAATGAATGTGCCAGCAATCCCTGCCAAAATGGAGCCAATTGCACTGACTGTGTGGACAGCTACACATGTACCTGCCCCGTGGGCTTCAATG GCATCCACTGCGAGAACAACACACCTGACTGTACTGAOAGOTCCTGCTTCAATGGTGGTACCTOTGTGGATGGTATCCTCCTTCACCTGTCTGTG TCCACCTGGCTTCACGGGCAGCTACTGTCAGTATGATGTCAATGAGTGTGATTCACGGCCCTGTCTGCACGGTGGTACCTGCCAAGACAGCTATGGT ACTTATAAGTGTACCTGCCCACAGGGCTACACTGGTCTCAACTGCCAGAACCTTGTGCGCTGGTGCGACTCGGCTCCCTGCAAGAATGGTGGCAGGT GCTGGCAGACCAACACGCAGTACCACTGTGAGTGCCGCAGCGGCTGGACTGGCGTCAACTGCGACGTGCTCAGTGTGTCCTGTGAGGTGGCTGCACA GAAGCGAGGCATTCACCTCACTCTCCTGTGCCAGCATGGAGGGCTCTGTGTGGATGAGGGAGATAAACATTACTGCCACTGCCAGGCAGGCTACACG GGCAGCTACTGTGAGGACGAGGTGGACGAGTGCTCACCTAACCCCTGCCAGAATGGAGCTACCTGCACTGACTATCTCGGCGGCTTTTCCTGCAAGT GTGTGGCTGGCTACCATGGGTCTAACTGCTCCGAGGAGATCCAACGAGTGCCTGTCCCAGCCCTGCCAGAATGGGGGTACCTGCATTGATCTGACCAA CTCCTACAAGTGTTCCTGCCCCCGGGGGACACAGGGTGTACACTGTGAGATCAATGTTGATGACTGCCATCCCCCCCTTGACCCTGCCTCCCGAAGC CCCAAGTGCTTCAACAATGGCACCTGTGTGGACCAGGTGGGTGGCTATACCTGCACCTGCCCACCAGGCTTCGTCGGGGAGCGGTGTGAGGGTGATG TCAATGAATGTCTCTCCAACCCCTGTGACCCACGTGGCACCCAGAACTGTGTGCAGCGTGTTAATGACTTCCACTGCGAGTGCCGGGCTGGCCACAC TGGACGCCGCTGTGAGTCAGTCATCAATGGCTGCAGGGGCAAACCTTGCAAGAATGGGGGTGTCTGTGCCGTGGCCTCCAACACCGCCCGTGGATTC ATCTGTAGGTGCCCTGCGGGCTTCGAGGGTGCCACATGTGAGAATGATGCCCGCACTTGTGGCAGCTTACGCTGTCTCAACGGTGGTACATGCATCT CGGGCCCACGTAGTCCCACCTGCCTATGCCTGGGATCCTTCACCGGCCCTGAGTGCCAGTTCCCAGCCAGCAGCCCCTGTGTGGGTAGCAACCCCTG CTACAATCAGGGCACCTGTGAGCCCACATCCGAGAACCCTTTCTACCGCTGTCTATGCCCTGCCAAATTCAACGGGCTACTGTGCCACATCCTGGAC TACAGCTTCACAGGTGGCGCTGGCCCGGACATTCCCCCACCGCAGATTGAGGAGGCCTGTGAGCTGCCTGAGTGCCAGGTGGATGCAGGCAATAAGG TCTGCAACCTGCAGTGTAATAATCACGCATGTGGCTGGGATGGTGGCGACTGCTCCCTCAACTTCAATGACCCCTGGAAGAACTGCACGCAGTCTCT ACAGTGCTGGAAGTATTTTAGCGACGGCCACTGTGACAGCCAGTGCAACTCGGCCGGCTGCCTCTTTGATGGCTTCGACTGCCAGCTCACCGAGGGA CAGTGCAACCCCCTGTATGACCAGTACTGCAAGGACCACTTCAGTGATGGCCACTGCGACCAGGGCTGTAACAGTGCCGAATGTGAGTGGGATGGCC CTTTCTGCGGGAGCTCAGCCACGTGCTGCACACCAACGTGGTCTTCAAGCGTGATGCGCAAGGCCAGCAGATGATCTTCCCGTACTATGGCCACGAG GAAGAGCTGCGCAAGCACCCAATCAAGCGCTCTACAGTGGGTTGGGCCACCTCTTCACTGCTTCCTGGTACCAGTGGTGGGCGCCAGCGCAGGGAGC TGGACCCCATGGACATCCGTGGCTCCATTGTCTACCTGGAGATCGACAACCGGCAATGTGTGCAGTCATCCTCGCAGTGCTTCCAGAGTGCCACCGA TGTGGCTGCCTTCCTAGGTGCTCTTGCGTCACTTGGCAGCCTCAATATTCCTTACAAGATTGAGGCCGTGAAGAGTGAGCCGGTGGAGCCTCCGCTG CCCTCGCAGCTGCACCTCATGTACGTGGCAGCGGCCGCCTTCGTGCTCCTGTTCTTTGTGGGCTGTGGGGTGCTGCTGTCCCGCAAGCGCCGGCGCC AGCATGGCCAGCTCTGGTTCCCTGAGGGTTTCAAAGTGTCAGAGGCCAGCAAGAAGAAGCGGAGAGAGCCCCTCGGCGAGGACTCAGTCGGCCTCAA GCCCCTGAAGAATGCCTCAGATGGTGCTCTGATGGACGACAATCAGAACGAGTGGGGAGACGAAGACCTGGAGACCAAGAAGTTCCGGTTTGAGGAG CCAGTAGTTCTCCCTGACCTGAGTGATCAGACTGACCACAGGCAGTGGACCCAGCAGCACCTGGACGCTGCTGACCTGCGCATGTCTGCCATGGCCC CAACACCGCCTCAGGGGGAGGTGGATGCTGACTGCATGGATGTCAATGTTCGAGGACCAGATGGCTTCACACCCCTCATGATTGCCTCCTGCAGTGG AGGGGGCCTTGAGACAGGCAACAGTGAAGAAGAAGAAGATGCACCTGCTGTCATCTCTGACTTCATCTACCAGGGCGCCAGCTTGCACAACCAGACA GACCGCACCGGGGAGACCGCCTTGCACTTGGCTGCCCGATACTCTCGTTCAGATCGTCGAAAGCGCCTTGAGGCCAGTGCAGATGCCAACATCCAGG ACAACATGGGCCGTACTCCGTTACATGCAGCAGTTTCTGCAGMGCTCAGGGTGTCTTCCAGATCCTGCTCCGGAACAGGGCCACAGATCTGGATGC CCGAATGCATGATGGCACAACTCCACTGATCCTGGCTGCGCGCCTGGCCGTGGAGGGCATGCTGGAGGACCTCATCAACTCACATGCTGACGTCAAT GCCGTGGATGACCTAGOCAAGTCGGCTTTGCATTGGGCGGCCGCGGTGAACAATGTGGATGCTGCTGTTGTGCTCCTGAAGAACGGAGCCAACAAGG ACATCGAGAACAACAAGGAGGAGACTTCCCTGTTCCTGTCGATCCGCCGTGAGAGCTATGAGACTGCCAAAGTGTTGCTGGACCACTTTGCCAACCG GGACATCACGGATCACATGGACCGATTGCCGCGGGACATCGCACAGGAGCGTATGCACCACGATATCGTGCGGCTTTTGGATGAGTACAACCTGGTG CGGTCCCCACAGCTGCATGGCACTGCCCTGGGTGGCACACCCACTCTGTCTCCCACACTCTGCTCGCCAAATGGCTACCCTGGCAATCTCAAGTCTG CCACACAGGGCAAGAAGGCCCGCAAGCCAAGCACCAAAGGGCTGGCTGGTGGTAGCAAGGAAGCTAAGGACCTCAAGGCACGGAGGAAGAGTTCCCA GGATGGCAAGOGCTGGCTGTTGGACAGCTCGTCGAGCATGCTGTCGCCTGTGGACTCCCTCGAGTCACCCCATGGCTACTTGTCAGATGTGGCCTCG CACCCCCTCCTCCCCTCCCCATTCCAGCAGTCTCCATCCATGCCTCTCAGCCACCTGCCTGGTATGCCTGACACCCACCTGGGCATCAGCCACTTGA ATGTGGCAGCCAAGCCTGAGATGGCAGCACTGGCTGGAGGTAGCCGGTTGGCCTTTGAGCACCCCCCGCCACGCCTCTCCCACCTGCCTGTAGCCTC CAGTOCCTGCCAGTGCTGAGTACCAATGGCACCGGGGCTATGAATTTCACCGTGGGTGCACCGGCAAGCTTGAATGGCCAGTGTGAGTGGCTTCCC CGGCTCCAGAATGGCATGGTGCCCAGCCAGTACAACCCACTACGGCCGGGTGTGACGCCGGGCACACTGAGCACACAGGCAGCTGGGCTCCAGCATA GCATGATGGGGCCACTACACAGCAGCCTCTCCACCAATACCTTGTCCCCGATTATTTACCAGGGCCTGCCCAACACACGGCTGGCAACACAGCCTCA CCTGGTGCAGACCCAGCAGGTGCAGCCACAGAACTTACCACTCCAGCCACAGAACTTACAGCCACCATCACAGCCACACCTCAGTGTGAGCTCGGCA GCCAATGGGCACCTGGGGCGGAGCTTCTTGAGTGGGGAGCCCAGTCAGGCAGATGTACAACCGCTGGGCCCCAGCAGTCTGCCTGTGCACACCATTC TGCCCCAOGAAAGCCAGGCCCTACCAACATCACTGCCATCCTCCATGGTCCCACCCATGACCACTACCCAGTTCCTGACCCCTCCATCACAGCACAG TTACTCCTCCTCCCCTGTGGACAACACCCCCAGCCACCAGCTGCAGGTGCCAGAGCCCACTTTCCTCACCCCATCCCCTGAGTCCCCTGACCAGTGG TCCAGCTCCTCCCCGCATTCCAACATCTCTGATTGGTCCGAGGGCATCTCCAGCCCGCCCACCACCATGCCGTCCCAGATCACCCACATTCCAGAGG CATTTAATAACAGAGATGTGGGATGCAGGACCCCAGCTTCCGTTCCCAAGCCCTGTTGGAAGTCCTTTCCAGTGCTTCAGGATGCTGGGGCGACC AAAGGAGCTTTTTAAAAAATGTTTTTATACAAAATAAGAGGACAAGAATTTCATTTTTTTTTTTAGTATTTATTTATGTACTTTTATTTTCCACAGA AACACTGCCTTTTTATTTATATGTATTGTTTTCTATGGCACTAGGGGACATATCTGTTCCAAGAAAATAAACTAGTTCTCAGAGCCTTGATTT TCCTGGTCAGGGTGAAGTTCCCTGTGTGTCTGTAAAATATGAACAAGGATTCATGATTTGTAAATGCTGTTTATTATTGATTGCTTCTTTCCAAAA TCGAAAAAAAAAA MOUSE SEQUENCE-CODING ATGCCACcGCTCCTGACGCCCCTTCTCTGCCTAACGCTGCTGCCCGCGCGCGCCGCAAGAGGCTTGAGATGCTCCCAGCCAAGTGGGACCTGCCTGA ATGGAGGTAGGTGCGAAGTGGCCAGCGCACTGAAGCCTGTGTTGCCAGCGGCAGCTTTGTGGGCCAACGATGCCAGGACCCCAATCCTTGCCTCAG CACACGGTGTAAGAATGCTGGAACGTGCTATGTTGTGGACCATGGTGGCATCGTGGACTATGCCTGCAGCTGTCCCCTGGGTTTCTCTGGGCCCCTC TGCCTGACACCTCTGGACA2GCCCTGCCTGGCCAACCCCTGCCGCAATGGGGGCACCTGTGACCTGCTCACTCTCACAGAGTACAAGTGCCGCTGCT CTCCAGGGTGGTCAGGAAATCATGTCAGCAGGCTGACCCCGTGCCTCCAACCCCTGTGCCAATGGTGGCCAGTGCCEGCCCTTTGAGTCTTCATA CATCTGTCGCTGCCCGCCTGGCTTCCATGGCCCCACCTGCAGGCAAGATGTTAATGAGTGCAGCCAGAACCCTGGGCTGTGCCGCCATGGAGGCCAC TGCCACAATGAGATCGGCTCCTATCGCTGTGCCTGCTGTGCCACCCATACTGGTCCCCACTGTGAACTGCCCTATGTGCCCTGCAGCCCCCTCACCCT GCCAGAATGGAGCAACCTGCCGTCCTACAGGGGACACCACCCACGAGTGTGCCTGCTTGCCAGGTTTTGCTGGACAGAACTGTGAAGAAAATGTGGA TGACTGTCCAGGAAACAACTGCAAGAATGGGGGTGCCTGTGTGGACGGCGTGAATACCTACAATTGCCGCTGCCCACCGGAGGTGACGGGTCAGTAC TGTACAGAGGATGTGGACGAATGTCAGCTCATGCCAAATGCCTGCCAGAATGCGGGAACCTGCCACAACACACACGGCGGCTACAACTGTGTGTGTG TCAATGGGTGGACTGGCGAGGACTGCAGTGAGAACATTGATGACTGTGCCAGTGCCGCCTGTTTCCAGGGTGCCACTTGCCACGACCGTGTGGCTTC CTTCTACTGCGAATGTCCGCATGGGCGCACAGGTCTGCTGTGCCACCTCAAGCATGCGTGCATCAGCAACCCCTGCAACGAGGGCTCCAACTGTGAC ACCAACCCTGTCAACGGCAAACGAATCTGCACCTGCCCCTCGGGGTACACAGGGCCAGCCTGCAGCCAGGACGTGGATGAGTGTGATCTGGGTGCCA ACCGTTGTGAGCACGCAGGCAAATGCCTCAACACACTGGGTTCTTTTGAGTGCCAGTGTCTACAGGGCTACACGGGACCCGGCTGTGAGATTGATGT TAATGAGTGCATCTCCAACCCATGTCAGAATGACGCCACTTGCCTGGACCAGATTGGGGAGTTCCAATGCATATGTGTATGCCAGGTTATGAAGGTGTA TACTGTGAAATCAACACGGATGAGTGCGCCAGCAGCCCCTGTCTGCACAATGGCCACTGCATGGACAAGATCCATGAGTTCCAATGTCAGTGCCCCA AAGGCTTCAACGGGCACCTGTGCCAGTATGATGTGGATGAGTGTGCCAGCACACCATGCAAGAACGGTGCCAAGTGCCTGGATGGGCCCAACACCTA TACCTGCGTGTGTACAGAGGTTACACAGGACCCACTGCGAAGTGGACATTGACGAGTGTGACCCTGACCCCTGCCACTATGGTTCCTGTAAGGAT GGTGTGGCCACCTTTACCTGCCTGTGCCAGCCAGGCTACAGGCCATCACTGTGAGACCAACATCAATGAGTGCCACAGCCAACCGTGCCGCCATG GGGGCACCTGCCAGGACCGTGACAACTCCTACCTCTGCTTATGCCTCAAGGGAACCACAGGGCCCAACTGTGAGATCAACCTGGATGACTGCGCCAG CAACCCCTGTGACTCTCGCACCTGTCTGGACAAOATTGATGGCTACGAATGTGCCTGTGAACCAGGCTACACAGGAAGCATGTGTAACGTCAACATT GACGAATGTGCGGGCAGCCCCTGCCACAACGGGGGCACTTGTGAGGATGGCATCGCGGGCTTCACTTGCCGCTGCCCCGAGGGCTACCATGACCCCA CGTGCCTGTCCGAGGTCAACGAGTGCAACAGTAACCCCTGCATCCACGGAGCTTGCCGGGATGGCCTCAATGGGTACAAGTGTGACTGTGCCCCTGG GTGGAGTGGAACAACTGTGACATCACAACAACGAGTGTGAGTCCAACCCTTGTGTCAACGGTGGCACCTGCAACGACATGACCAGTGGCTACGTA TGCACCTGCCGAGAAGGCTTCAGTGGCCCTAATTGCCAGACCAACATCAACGAATGTGCCTCCAACCCCTGCCTGAACCAGGGGACCTGCATTGATG ATGTCGCTGGATACAAGTGCAACTGTCCTCTGCCATATACAGGAGCCACGTGTGAGGTSGTGTTGGCCCCATGTGCTACCAGCCCCTGCAAAAACAG CGGCGTATGCAAGGAGTCTGAAGACTATGAGAGTTTCTCCTGTGTCTGTCCCACAGGCTGGCAAGGTCAAACCTGCGAGGTTGACATCAATGAGTGT GTGAAAAGCCCATGTCGCCATGGGGCCTCCTGCCAGAACACCAATGGCAGCTACCGCTGCCTCTGCCAGGCCGGCThTACAGGTCGCAACTGTGAGA GTGACATCGATGACTGCCGCCCCAACCCGTGTCACAATGGGGGTTCCTGCACCGATGGCATCAACACAGCCTTCTGCGACTGCCTGCCCGGCTTCCA GGGTGCCTTCTGTGAGGAGGACATCAATGAATGTGCCAGCAATCCCTGCCAAAATGGAGCCAATTGCACTGACTGTGTGGACAGCTACACATGTACC TGCCCCGTGGGCTTCAATGGCATCCACTGCGAGAACAACACACCTGACTGTACTGAGAGCTCCTGCTTCAATGGTGGTACCTGTGTGGATGGTATCA ACTCCTTCACCTGTCTGTGTCCACCTGGCTTCACGGGCAGCTACTGTCAGTATGATGTCAATGAGTGTGATTCACGGCCCTGTCTGCACGGTGGTAC CTGCCAAGACAGCTATGGTACTTATAAGTGTACCTGCCCACAGGGCTACACTGGTCTCAACTGCCAGAACCTTGTGCGCTGGTGCGACTCGGCTCCC TGCAAGAATGGTGGCAGGTGCTGGCAGACCAACACGCAGTACCACTGTGAGTGCCGCAGCGGCTGGACTGGCGTCAACTGCGACGTGCTCAGTGTGT CCTGTGAGGTGGCTGCACAGAGCGAGGCATTGACGTCACTCTCCTGTGCCAGCATGGAGGGCTCTGTGTGGATGAGGGAGATAAACATTACTGCCA CTGCCAGGCAGGCTACACGGGCAGCTACTGTGAGGACGAGGTGGACGAGTGCTCACCTAACCCCTGCCAGAATGGAGCTACCTGCACTGACTATCTC GGCGGCTTTTCCTGCAAGTGTGTGGCTGGCTACCATGGGTCTAACTGCTCCGAGGAGATCAACGAGTGCCTGTCCCAGCCCTGCCAGAATGGGGGTA CCTGCATTGATCTGACCAACTCCTACAAGTGTTCCTGCCCCCGGGGGACACAGGGTGTACACTGTGAGATCAATGTTGATGACTGCCATCCCCCCCT TGACCCTGCCTCCCGAAGCCCCAAGTGCTTCAACAATGGCACCTGTGTGGACCAGGTGGGTGGCTATACCTGCACCTGCCCACCAGGCTTCGTCGGG GAGCGGTGTGAGGGTGATGTCAATGAATGTCTCTCCAACCCCTGTGACCCACGTGGCACCCAGAACTGTGTGCAGCGTGTTAATGACTTCCACTGCG AGTGCCGGGCTGGCCACACTGGACGCCGCTGTGAGTCAGTCATCAATGGCTGCAGGGGCAAACCTTGCAAGAATGGGGGTGTCTGTGCCGTGGCCTC CAACACCGCCCGTGGATTCATCTGTAGTGCCCTGCGGGCTTCGAGGGTGCCACATGTGAGAATGATGCCCGCACTTGTGGCAGCTTACGCTGTCTC AACGGTGGTACATGCATCTCGGGCCCACGTAGTCCCACCTGCCTATGCCTGGGATCCTTCAOCGGCCCTGAGTGCCAGTTCCCAGCCAGCAGCCCCT GTGTGGGTAGCAACCCCTGCTACAATCAGGGCACCTGTGAGCCCACATCCGAGAACCCTTTCTACCGCTGTCTATGCCCTGCCAAATTCAACGGGCT ACTGTGCCACATCCTGGACTACAGCTTCACAGGTGGCGCTGGCCCGGACATTCCCCCACCGCAGATTGAGGAGGCCTGTGAGCTGCCTGAGTGCCAG GTGGATGCAGGCAATAAGGTCTGCAACCTGCAGTGTAATAATCACGCATGTGGCTGGGATGGTGGCGACTGCTCCCTCAACTTCAATGACCCCTGGA AGAACTGCACGCAGTCTCTACAGTGCTGGAAGTATTTTAGCGACGGCCACTGTGACAGCCAGTGCAACTCGGCCGGCTGCCTCTTTGATGGCTTCGA CTGCCAGCTCACCGAGGGACAGTGCAACCCCCTGTATGACCAGTACTGCAAGGACCACTTCAGTGATGGCCACTGCGACCAGGGCTGTAACAGTGCC GAATGTGAGTGGGATGGCCTAGACTGTGCTGAGCATGTACCCGAGCGGCTGGCAGCGGGCACCCTGGTCCTGGTGGTGCTGCTTCCACCCGACCAGC TACGGAACAACTCCTTCCACTTTCTGCGGGAGCTCAGCCACGTGCTGCACACCAACGTGGTCTTCAAGCGTGATGCGCAAGGCCAGCAGATGATCTT CCCGTACTATGGCCACGAGGAAGAGCTGCGCAAGCACCCAATCAAGCGCTCTACAGTGGGTTGGGCCACCTCTTCACTGCTTCCTGGTACCAGTGGT GGGCGCCAGCGCAGGGAGCTGGACCCCATGGACATCCGTGGCTCCATTGTCTACCTGGAGATCGACAACCGGCAATGTGTGCAGTCATCCTCGCAGT GCTTCCAGAGTGCCACCGATGTGGCTGCCTTCCTAGGTGCTCTTGCGTCACTTGGCAGCCTCAATATTCCTTACAAGATTGAGGCCGTGAAGAGTGA GCCGGTGGAGCCTCCGCTGCCCTCGCAGCTGCACCTCATGTACGTGGCAGCGGCCGCCTTCGTGCTCCTGTTCTTTGTGGGCTGTGGGGTGCTGCTG TCCCGCAAGCGCCGGCGCCAGCATGGCCAGCTCTGGTTCCCTGAGGGTTTCAAAGTGTCAGAGGCCAGCAAGAAGAAGCGGAGAGAGCCCCTCGGCG AGGACTCAGTCGGCCTCAAGCCCCTGAAGAATGCCTCAGATGGTGCTCTGATGGACGACAATCAGAACGAGTGGGGAGACGAAGACCTGGAGACCAA GAAGTTCCGGTTTGAGGAGCCAGTAGTTCTCCCTGACCTGAGTGATCAGACTGACCACAGGCAGTGGACCCAGCAGCACCTGGACGCTGCTGACCTG CGCATGTCTGCCATGGCCCCAACACCGCCTCAGGGGGAGGTGGATGCTGACTGCATGGATGTCAATGTTCGAGGACCAGATGGCTTCACACCCCTCA TGATTGCCTCCTGCAGTGGAGGGGGCCTTGAGACAGGCAACAGTGAAGAAGAAGAAGATGCACCTGCTGTCATCTCTGACTTCATCTACCAGGGCGC CAGCTTGCACAACCAGACAGACCGCACCGGGGAGACCGCCTTGCACTTGGCTGCCCGATGCTCTCGTTCAGATCGTCGAAAGCGCCTTGAGGCCAGT GCAGATGCCAACATCCAGGACAACATGGGCCGTACTCCGTTACATGCAGCAGTTTCTGCAGATGCTCAGGGTGTCTTCCAGATCCTGCTCCGGAACA GGGCCACAGATCTGGATGCCCGAATGCATGATGGCACAACTCCACTGATCCTGGCTGCGCGCCTGGCCGTGGAGGQCATGCTGGAGGACCTCATCAA CTCACATGCTGACGTCAATGCCGTGGATGACCTAGGCAAGTCGGCTTTGCATTGGGCGGCCGCGGTGAACAATGTGGATGCTGCTGTTGTGCTCCTG AAGAACGGAGCCAACAAGGACATCGAGAACAACAAGGAGGAGACTTCCCTGT12CCTGTCGATCCGCCGTGAGAGCTATGAGACTGCCAAGTGTTGC TGGACCACTTTGCCAACCGGGACATCACGGATCACATGGACCGATTGCCGCGGGACATCGCACAGGAGCGTATGCACCACGATATCGTGCGGCTTTT GGATGAGTACAACCTGGTGCGGTCCCCACAGCTGCATGGCACTGCCCTGGGTGGCACACCCACTCTGTCTCCCACACTCTGCTCGCCAAATGGCTAC CCTGGCAATCTCAAGTCTGCCACACAGGGCAAGAGGCCCGCAAGCCAAGCACCAAAGGGCTGGCTTGTGGTAGCAAGGAAGCTAAGGACCTCAAGG CACGGAGGAAGAGTTCCCAGGATGGCAAGGGCTGGCTGTTGGACAGCTCGTCGAGCATGCTGTCGCCTGTGGACTCCCTCGAGTCACCCCATGGCTA CTTGTCAGATGTGGCCTCGCACCCCCTCCTCCCCTCCCCATTCCAGCAGTCTCCATCCATGCCTCTCAGCCACCTGCCTGGTATGCCTGACACCCAC CTGGGCATCAGCCACTTGAATGTGGCAGCCAAGCCTGAGATGGCAGCACTGGCTGGAGGTAGCCGGTTGGCCTTTGAGCACCCCCCGCCACGCCTCT CCCACCTGCCTGTAGCCTCCAGTGCCTGCACAGTGTGAGTACCAATGGCACCGGGGCTATGAATTTCACCGTGGQTGCACCGGCAAGCTTGAATGG CCAGTGTGAGTGGCTTCCCCGGCTCCAGAATGGCATGGTGCCCAGCCAGTACAACCCACTACGGCCGGGTGTGACGCCGGGCACACTGAGCACACAG GCAGCTGGGCTCCAGCATAGCATGATGGGGCCACTACACCAGCCTCTCCACCATACCTTGTCCCCGATTATTTACCAGGGCCTGCCCAACACAC GGCTGGCAACACAGCCTCACCTGGTGCAGACCCAGCAGGTGCAGCCACAGAACTTACCACTCCAGCCACAGAACTTACAGCCACCATCACAGCCACA CCTCAGTGTGAGCTCGGCAGCCAATGGGCACCTGGGGCGGAGCTTCTTGAGTGGGAGCCCAGTCAGGCAGATGTACAACCGCTGGGCCCCAGCAGT CTGCCTGTGCACACCATTCTGCCCCAGGAAAGCCAGGCCCTACCCATCACTGCCATCCTCCATGGTCCCACCATGACCACTACCCAGTTCCTGA CCCCTCCAACAGCACAGTTACTCCTCCTCCCCTGTGGACAAACACCCCCAGCCACCAGCTGCAGGTGCCAGAGAGCCCACTTTCCTCACCCATCCCC TGAGTCCCCTGACCAGTGGTCCAGCTCCTCCCCGCATTCCAACATCTCTGATTGGTCCGAGGGCATCTCCAGCCCGCCCACCACCATGCCGTCCCAG ATCACCCACATTCCAGAGGCATTTAAATAA HUMAN SEQUENCE-GENOMIC CAGGCCAGGGAGATAATGGGGGACAGGGAAGATAACGCAGTCCCCACGGCTATAAACAGGAAGCTCGGCCATGGGCTTGTGCAGAAAAAGGCCCTCG GCTGTGCACGTGGTTCCTACATAGCCTTTGCCAGACACCCTGCGTGGCCCGGAGGTCTCCAGGCCGTGCCCCGTGCCCCGACACGCAGGATGTGCT GGGGCCTGGGCCTGTCCCCTCCATCGCAGCCCTTGTTTGTTGGCCTCCCGTGATGGGCGTTTGCTGCCTGTGACACGGAGCCCCAGGATTAGTTTC AGGCCTCGGTCTCAGGCCAGGGCCTTTCCTCGTCACCCAGAGATGAGGGGGCTTGCGTCCGGGGTGGGCCCAGGTCCCTGCAGTGTCGTGGAGCCCA CCCGACTGAGGCCGCCTCTCCTGGTGCAGTCCTTGTTCCTGGGCACGCCTGGTGGGGTGAGGCCTAGGCTGTGCCCCGCTGCCAACCGGGAATGAGG GGTGGCTTCTGAGCGTGACATTTGTGCAGCTTGTCTTCAGCGTCCCCCATCTGTGTCTCCACTCCTCCCTGGGTCAGGGTCCTGGCACAGCCGGGAG CGCTCAGGGGTCTCGGTGCACATTTGCCTCCCGGCGGGACCAGCAGACGGCACTCTGATGGCGGAAAGACCAGCAGGCGGTGGCCGATTTGGGAGAT CCCTCTGGGTGAGGCTCCCGGGGTCACGTGTGTCTCCTTCCCGCAGGTGCCACGTGTGAGGTGGTGCTGGCCCCGTGTGCCCCAGCCCCTGCAGAA ACGGCGGGGAGTGCAGGCAATCCGAGGACTATGAGAGCTTCTCCTGTGTCTGCCCCACGGGCTGGCAAGGTGAGGCTGGCCAGGGCCCGGTGAGGGC TGGGATGGGAGGTCAGGATGTCTGCGGGACACAGGCAGCTCCCAGGCAGGCTAGATGAGTCTTTGAAGAGGAGCCGGTGGGTGCTGAGGAGGCCCTG GTCGGAGAAGTTCTGGAATCAGGAATTGACCTGGGAGCACCGTTCCCAACTCCAGTTCCTGTGACCTTCTTAGGCCAAAATTAGGGGAGAGGGGATG GTCCTGGGGTCACGGAAGCCCACTCCTGGGTCGGGAGAGGCACTGTAGGTGGGTGGGCCAGCCTGGGAAGGGCCTGGAGGGCCAGGGGCCGCTGGTG ACCAACCGGCCTCCTCCTGCCCCACAGGGCAGACCTGTGAGGTCGACATCAACGAGTGCGTTCTGAGCCCGTGCCGGCACGGCGCATCCTGCCAGAA CACCCACGGCGGCTACCGCTGCCACTGCCAGGCCGGCTACAGTGGGCGCAACTGCGAGACCGACATCGACGACTGCCGGCCCAGTGAGTAGCCCCGC GGCTCTGGCCTCCTCCAGGAAGCTCTCAGGCCTCAGTTCCCCCGGGCAGGGTTGGTGCGCATGGTGCTGGCCATAAGCACCCAGGGAGGCCGGAGTG TGGCCGGGGAGGGTTGGGTCAGGTGTGGGGGATGTGCTGAGGGATGGCCAGGGTGGTTCAGGAGGGCCCCAGAGCCGGCTTGCTCCTCCCTGCACTT CGCGGAAGAGTCACGAGAGCCCCTCCCACGGCTCTTCACTGAGCCGAGGATGGCTCGGGCCCGGCCTGCACTCCCGCCTGGCTCATCGGGCCCCGCT GCAGGCCAGGGCTCTCAGGCCTCCCAGCCCTGCTTCACAGAGGTTGAGGTTGGCAGAAGCCGGGGGTCTTGCTGGCATCACCTGGCAGGCAGAGGCA AGAACTGTCTCTCCTCCCCTGCTCGGTCTGTGAAGCCTGCAAAGCTGCCCCCTGCCCTGGAGCTTGAGGACAGGAGCAGGTGGGGAGAGAGACCCCA AGCACAGGAGACGGGTGTGACGCAGCCTGTGGGTGCTGGGGCTCCCCACCAGACACCTTTGTCACAGGGCTGCTTGCCGCAGCCTCGGCAACGAAAG GCTGGGCTGTCCCCAGCCATGCAGCCTTCCCGGCCCCCTCCOGCAGGTGTGGGTTTGTGCCTGCCCTCACACTCACCCTTCCGTCCTCTCCCAGAC CCGTGTCACAACGGGGGCTCCTGCACAGACGGCATCAACACGGCCTTCTGCGACTGCCTGCCCGGCTTCCGGGGCACTTTCTGTGAGGAGGACATCA ACGAGTGTGCCAGTGACCCCTGCCGCAACGGGGCCAACTGCACGGACTGCGTGGACAGCTACACGTGCACCTGCCCCGCAGGCTTCAGCGGGATCCA CTGTGAGAACAACACGCCTGACTGCACAGAGAGGTGTGCGGGGCTCGAGTGAGGCCGTGGAAGGGAACGGGCGGTGCGGGCCACACGCAGTAGCTGG CAGCCTGGCACACCATGCAGGCGTCCGCCTAGGCCGGCTGGGCACTTAGCGCTGGCTGCATTGAGTCCAGACATTGTTCATTGTACCGACCTGTCCC TCCTGAGAGGGCCATTGTGACCTCCTCCTGTGTCCCGCACCAGGAGCGCCGGTAGTCTGTCCTGAAGAACTGGTGCGCTTCCTTCTATTAGACAACG AGAACTCTGTCCGTTCTTGTTTCCTTTTTGCCGTGTTTGCCAGGAAGCTCATTTGGTAAACGTCAGTCTCGTCCCTGGTTTCTGACGTAATTACCTC CCGTGTTACCAGGACGGTTTCTGGTTTCTCCCTCATTTACTTTAACCACCCTATGCCCACGCGTTTGGTAAAACCACTCTCGACCTGACTTATAAAG AAAGCAGGGGAGGGAGGTGTGACGTGGTGTGAGAGCCGGGCCCCGGGTTCCCACTGGCCTCCCTGGGTCAGCCAGGCTGCCCTGGGCCTGTCCTGGC CATCAGGCCCCTAGGGTTGAGCAGAAGGGGAGGTGCTGGCGAGGCAGAATCTGCTGGAGCGGGGACCCACCAATGCCCTCCGCTCAGCCCCCGCCTG CCCACCCCCTTGCAGcTCCTGCTTCAACGGTGGCACCTGCGTGGACGGCATCAACTCGTTCACCTGCCTGTGTCCACCCGGCTTCACGGGCAGCTAC TGCCAGCACGATGTCAATGAGTGCGACTCACAGCCCTGCCTGCATGGCGGCACCTGTCAGGACGGCTGCGGCTCCTACAGGTGCACCTGCCCCCAGG GCTACACTGGCCCCAACTGCCAGGTGAGTGCGCCGGCCACAGAGGTGCCCGAAGGAGGGGCCCTGGGTGGGTGCCTGCCTGCGGGAGGTGGGAACGG TCACCCCCAGGTCCCACTGTGTCGGCTCGGGGTCACCCCCACACCCCCGGGCAGAGGGTTTCTGGGGATCTGAGCAGCCGGTGAAGGAACCTGATGC GGAAGCAGCAGGCACCTTCGTTTCAATCCCAGGTTTCTGGAGCCGGGGCGGGAGCTCAGGAATTGGGGAATTGAGGAAAAGTGTTCCTTCTAGCAAA GGCCGAGGGTGGTCTGGACCTGCTGAGGGCCCTGAGGGAGACCCAGCCCAGGCTGTTCCTGGTGTGGGGGTGGTGGGGAGTCCAGGGGCGGCAGTCT CCACTTCTGTAGAATGGGTTGCAGCCTGGGTTGGAGTAGGCCCCTTGGCGGATGTGCGTTCTGAGCTACCGGGGAAATGGCCGGGGCGCGGGCACCC AGCTGACCCCAATCTGTCCCCAGAACCTTGTGCACTGGTGTGACTCCTCGCCCTGCAAGAACGGCGGCAAATGCTGGCAGACCCACACCCAGTACCG CTGCGAGTGCCCCAGCGGCTGGACCGGCCTTTACTGCGACGTGCCCAGCGTGTCCTGTGAGGTGGCTGCGCAGCGACAAGGTAACCTGCTGTGCCCA CCCGGCTCGGGTCCCAGCCCATCAAGGTCCTCTGTGGGCCTGGGCCTCACCTGTCTACCACCCCATCCCCCGCAGGTGTTGACGTTGCCCGCCTGTG CCAGCATGGAGGGCTCTGTGTGGACGCGGGCAACACGCACCACTGCCGCTGCCAGGCGGGCTACACAGGCAGCTACTGTGAGGACCTGGTGGACGAG TGCTCACCCAGCCCCTGCCAGAACGGGGCCACCTGCACGGACTACCTGGGCGGCTACTCCTGCAAGGTGGGGGTCCCTCCTAGGGTAAGGGTTGTGG CCGGCACGAGTGTTGCCACACACCAGGCCCTGGCTGGGAGCTGGCCCAGTGGAGAAAACTGAACCTGATAGGCCCATGCACTGTTCAGTCTCATTAG GGGAGGGCTGGGGTAATCAGGGTAGACTGCCTGGAAGAGGTGGCCTGTGGAAAGCCTGAAGGAGGGTACCTATACTGAGAAGTGGGATGGGGTTTTC CCTTCCCCTAGATTGTGTCTGGGCTTGGCCAACACCTACCCTGAGGCCCTCACCTCTATCCTATGGGACGGGGTCCACCCACCCCCAACAGGCAGTG ACTCCGGTCACCGAGGCCCCGCCAGGGTCTGTTGGGCTGGGTCTCTCTCCAGGTCTGACAGGAGCGAGGGGCCCGTGGCTTCGCTGGACCTGAGGGC AGCTCATGTGGCCCTGTCAGCCCTCACAGTGGGGTGTGGGAGCACTGCATCCTGGCGCCGGCTGAGCCGAAGGGCCCCTCGTTCTGTCGCCTGCACA GTGCGTGGCCGGCTACCACGGGGTGAACTGCTCTGAGGAGATCGACGAGTGCCTCTCCCACCCCTGCCAGAACGGGGGCACCTGCCTCGACCTCCCC AACACCTACAAGTGCTCCTGCCCACGGGGCACTCAGGGTAAGGGCCGCTGCACGGAGGGCTGGTGTTGGCCATCCATGGCCAGGGCAGGGGCAGGGC AGGCACCCCGGGACCGGCCAGAGGCATCCAGGAACCAGCCAGAAACTCCCGTTTTCCTGTGTGAGGCCAAGGCCGACTCACAGCTGCCCAGGGAAAG GGCCCAGAGCGGGGGTCCCAGTGGGAAGGGCGTCTCCACGGCACCCTTGACACCTGCCTCTCCCGAGTGTCCGTGCAGCCCCAGACCTGAGCGCTTG TCTTCCGGGACGGACACGCGGCACGGCAGGGCCGGGGTGTGGCGGGCTTGGGCCACTGACGAAACCTGGCCCCGCAGGTGNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN 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CCGTGGCCCACCTGCCTCTCTCCCCTAAGCCCCGAGGCTGGGGTACAGTTGATTCTGGAAACTTAGAATTGGGGTGAGAGCTTTCATCCTTGGGG GTGTTTCCCATTCAGAGTAGACGTGGGGGGGTCCTGGAGTCCTCCTGTTCTTCCACCCCCCTTCCTGGGGTGATACCGCAGGGCCACTGTGTCCC TGTAAATTACTCTTTTCTGAAACCTTCTTGAGACATGGAAAGCGTTGATTTTCTTTTTCTTTTTTTTTTTTCTTTTTTTTTTGTTTTTGAGATGGAG TCTCGCTCCGTCACCCAGGCTGAGTGCAGTGGCACGATCTCGGCTCCCTGCAACCTCCACCTCTCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCC CCAGTAGCTGGGACTACAGCGCCTGCCACCACACCTGGCTAATTTTTGTATTTTTAGCAGCGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCG ACTCCTGACCTCAGGTGATCCGCCCACCTCGGCCTCCCCCAGTGCTAGGATGACAGCGTGAGCCTCCGCATCCTGCTGAAGCATTAATTTTCTAAC TGCATGCTTCTGGGGTCCTCTTTTTCCTGGGTGGATTTTGGGTGCCAGGTCTTGGGCAGGTCAGGAAGCAGTTGCCCGCCAGGAGTTTAAGCTGGAT TCGGCTCTGTCCACTGAGCAGCCCAGGCGGACTTCAGCTGCCCCTTGGTGGCTGTGTGCACGGGGCCACCAAGTGCTGGGTGCATGCATCCACACCGT GGCCCCTTGAGCTTGGGGCTGCTGCCCCCCTCCCCCTGGGCTGCAGCTGGGGACCGGCCCTCCAGACTGAGCACCCGTCTCTGCCTCTGCAGATGGC TTCACCCCGCTCATGATCGCCTCCTGCAGCGGGGGCGGCCTGGAGACGGGCAACAGCGAGGAAGAGGAGGACGCGCCGGCCGTCATCTCCGACTTCA TCTACCAGGGCGCCAGCCTGCACAACCAGACAGACCGCACGGGCGAGACCGCCTTGCACCTGGCCGCCCGCTACTCACGCTCTGATGCCGCCAGCG CCTGCTGGAGGCCAGCGCAGATGCCAACATCCAGGACAACATGGGCCGCACCCCGCTGCATGCGGCTGTGTCTGCCGACGCACAAGGTGTCTTCCAG GTAGGCAGTGGCTGCCTGTGTGCCCACCTGCCCTCCTCAGGGCCGCCTGGTGGTCTGGGGCAGTGGCCAGGCTTACTGTGGCCCTGGGAGCCTGACCC CGAGCACAGCTGAGTCCGGGACAACTGGTGCCTCCACCTGGGACCTTCGCAGTCAGCGAGGTGCGAGAGGGGCGTCGGGCCCATCTGTGTTCTC CAGGGAAGTCAGGCAGAGGCGGGTCTGGCAGGAGGCCTGGGGGATCTGCTGAGTGAGGCAGCACCTCCCACCCCCAGCAAAACAGGCTCCATCAGG GTTGTGGGCCTTGCTCAAGTCCAGGTTCCACTGCTGCAGCCCCGCAGCCCCGCCCCTCCCTCAACCTTGGCTGCCGGCGTAGCCTGTGGCAGTG AGAAGCAGGGTTTAGAGGCTGCCGCTCGGTGCCTGCAGACCTAGGGCTCAGCTTGCCGGTGAGCTCGTGGCAAGAATGGATTTAGGGATTTGGATGC CTGGGTCTCCAGGGAGTGTCCCTGGCAGGGGCTGCCTTTGCAGTCACCCCTGCTGCGAGTCCCCAGGCTCCAGGCGGCCCTGGAGCAAGCAGGTTCA GATGGGCACAGCCCGGGGAGTTACCACAGAGCTTCTCATTCCTGATTTCTAGCTCAGGTGACACATTGTCATCTTGCAGAAATAAATGTAGGTGA GCAGAAGAGCGTGGAAGGGAGCCCCGTGCGGGTTTGGTGTGTGCCTCTCTCAGCTGCCTTCTTTGCACAGATGTGGAAGTTCCCAGGTGCTTTGCA GGAATCAGGCCAAGTTGCCTTTTGCACCCGCCAGTGAGCAGGGGCCATTCCTCCTGCCAGATGCCAAGACCCGGCTGCATTACAAGGGCTGCCCACC CCCTCTCTGGGCAGAGCCGGACACTAGCTCGGCGGTTCTGAGACGGCTGTAGGGCCGTGAGCCCGGCTTCCTAGTGCCAGCTGTAACCGCCGTTGG GGGCAGGGACTTGACCTCTCTGTTTTGTAGGTGGTCATGGCAGCTAGGACCACAGTGAGGATTAATGAGGCCACACGTGGTCACGATGGATCCCAC TGTCACCAAGGGGCCTGTCTGTGGGCAGCACAGCCCCTGCCCCCATCCGGGCCCCTCCTCAGGGGCAGCCCCATGGCGTTTCGTCTTGCCCGGCCGT GCCGATCTCAGGAGGGTCTCGTCTGTGTCCGGAAGACAGTGGGGCTTCCCGTCCAGGCGTTCGTTCTGGCAGGAGGCATCGGTGTACGTCTGCCCA GCACCCGCCTGAGCCTCTCCCTGTTGCCCAGATCCTGATCCGGAACCGAGCCACAGACCTGGATGCCCGCATGCATGATGGCACGACGCCACTGATC CTGGCTGCCCGCCTGGCCGTGGAGGGCATGCTGGAGGACCTCATCAACTCACACGCCGACGTCAACGCCGTAGATGACCTGGGTGAGCCCACGGGGG CACGGCTGCTCTGTCGTGGGGCGGGACCGCCACAGGGACGGGTGGGACTGGGTTGCCTCCAGCTGGTCTCCAACTACCCCATCTGCTTCTTTCACG CAGGCAAGTCCGCCCTGCACTGGGCCGCCGCCGTGAACAATGTGGATGCCGCAGTTGTGCTCCTGAAGAACGGGGCTAACAAAGATATGCAGAACAA CAGGGTGAGCGCGAGGCTGGGATGCCAGGGGAGACGTGAGGGCTGAATCCACACAGAGAAGTGAGGGCCAAACCCACGGGGCGCAGGGACACAAGGGCC TGACCCACAGGGTCTCGAGGGTCGCTGGGCCCGCATGTGGGCCCCACCCGCATGATCGGGCACCTCGTTAGTGCTCCTGCCCTCCTTCAGCCCCTG TTTATGGAGCCCTTCCAAGTGCGTCCAGCTGTCAGGACACGGCGGCTCGCCCCTCAGACCCAGCCCTACCCTCCTGGGCGGCAGTCATGGCAGGG CACACAGCCTGGCGTGGGGAACGCTGCTGCTGCCACTGCTGTGTCACCGTCACCTGGACCTCACCTTCTGTCCCCAGCTGTCACCAGGCGGGGGTGG GGATGGGATGTGGTGACGCAGGTGGTGCAGATTGAGCCAGAACACGCGTGGCGGCAGCTCCCTGCGGGGCGGGGCCTCTTGGTGTGTTCACCAAGG CCAGGACCTCAAGGCTCAGAGGAAGAAGTCTCAGGACTATATCCAAGGGGAGCCACCCCCAGCCCTCATCCTGGCCCTGCAGCTCCTGGCCCTGCA GCTGCTGTTGGTTTCCCCTGGGTGCTCAGGGCACAGGTGCAGACACCCCCACCTCCCTGCCGCCAGAACCCCCACCCCCGCCCCCAACTCCTGCTGC CCCCTTGGCATGTCAGGCTCAGGCGTCTCTCCCTCCTGGGTGAGGGCACACAGCGGGCCTGGGCACCGGGGCATGTTGGCCCAGGCGCTCCCCAGTC CGTGGCAGCATGGCCCCACAGAGACTGGGCCCCAGAGGGCATCAAGGCCTGGGAAGCCCCTTCCCACTCCCACACAGCAGCCTCACCCAGACCTGTG ACGTGTCCACCGCACAGAGGAGACCCCAGGAAGGAGCTTGGTGGCCACCAGGGTGGCTTGATGGCCGTCCGATACGAGCTCCCTCCCTGGTGCCC TCGCCGGTGCCTCTGAACCGCTCCAGGAATTTCCTTTTGTGCCTTATTGGGGGCAGGGAAGAGGGCCTGCAGTTGGTTAGATTTTCAGTGGGGTCTG TGACCCCCCCATAGAGGTGGAGCCCCGCTGATCTAGGGTAGAGGACTGCACAGATCCCCTCTCTGGGTGGGTTTCAGAAGATGTATCAAAGCCTTAA CATTTAACAAGAGTCAGGCTAGGTGGTTGCAGGACGCTGGGGTGGGGTCCTGAGGAGCAGCCTGCCTGCCCCCACCCCGCGGAGGAGGTTGTACTGC TGCTTCCTCTGGTGATGGAACCTTGGGGAGGGTCCCCACGCCTGGCCTGGCCCCCCTCACCGGCCCCCGCCCTCATCCCCCAGGAGGAGACACCNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGCCAACCGGGACATCACGGATCATATGGACCGCCTGCCGCGCGACATC GCACAGGAGCGCATGCATCACGACATCGTGAGGCTGCTGGACGAGTACAACCTGGTGCGCAGCCCGCAGCTGCACGGAGCCCCGCTGGGGGGCACGC CCACCCTGTCGCCCCCGCTCTGCTCGCCCAACGGCTACCTGGGCAGCCTCAAGCCCGGCGTGCAGGGCAAGAAGGTCCGCAAGCCCAGCAGCAAAGG CCTGGCCTGTGGAAGCAAGGAGGCCAAGGACCTCAAGGCACGGAGGAAGAAGTCCCAGGATGGCAAGGGCTGCCTGCTGGACAGCTCCGGCATGCTC TCGCCCGTGGACTCCCTGGAGTCACCCCATGGCTACCTGTCAGACGTGGCCTCGCCGCCACTGCTGCCCTCCCCGTTCCAGCAGTCTCCGTCCGTGC CCCTCAACCACCTGCCTGGGATGCCCGACACCCACCTGGGCATCGGGCACCTGAACGTGGCGGCCAAGCCCGAGATGGCGGCGCTGGGTGGGGGCGG CCGGCTGGCCTTTGAGACTGGCCCACCTCGTCTCTCCCACCTGCCTGTGGCCTCTGGCACCAGCACCGTCCTGGGCTCCAGCAGCGGAGGGGCCCTG AATTTCACTGTGGGCGGGTCCACCAGTTTGAATGGTCAATGCGAGTGGCTGTCCCGGCTGCAGAGCGGCATGGTGCCGAACCAATACAACCCTCTGC GGGGGAGTGTGGCACCAGGCCCCCTGAGCACACAGGCCCCCTCCCTGCAGCATGGCATGGTAGGCCCGCTGCACAGTAGCCTTGCTGCCAGCGCCCT GTCCCAGATGATGAGCTACCAGGGCCTGCCCAGCACCCGGCTGGCCACCCAGCCTCACCTGGTGCAGACCCAGCAGGTGCAGCCACAAAACTTACAG ATGCAGCAGCAGAACCTGCAGCCAGCAAACATCCAGCAGCAGCAAAGCCTGCAGCCGCCACCACCACCACCACAGCCQCACCTTGGCGTGAGCTCAG CAGCCAGCGGCCACCTGGGCCGGAGCTTCCTGAGTGGAGAGCCGAGCCAGGCAGACGTGCAGCCACTGGGCCCCAGCAGCCTGGCGGTGCACACTAT TCTGCCCCAGGAGAGCCCCGCCCTGCCCACGTCGCTGCCATCCTCGCTGGTCCCACCCGTGACCGCAGCCCAGTTCCTGACGCCCCCCTCGCAGCAC AGCTACTCCTCGCCTGTGGACAACACCCCCAGCCACCAGCTACAGGTGCCTGAGCACCCCTTCCTCACCCCGTCCCCTGAGTCCCCTGACCAGTGGT CCAGCTCGTCCCCGCATTCCAACGTCTCCGACTGGTCCGAGGGCGTCTCCAGCCCTCCCACCAGCATGCAGTCCCAGATCGCCCGCATTCCGGAGGC CTTCAAGTAAACGGCGCGCCCCACGAGACCCCGGCTTCCTTTCCCAAGCCTTCGGGCGTCTGTGTGCGCTCTGTGGATGCCAGGGCCGACCAGAGGA GCCTTTTTAAAACACATGTTTTTATACAAAATAAGAACAAGGATTTTAATTTTTTTTAGTATTTATTTATGTACTTTTATTTTACACAGAAACACTG CCTTTTTATTTATATGTACTGTTTTATCTGGCCCCAGGTAGAAACTTTTATCTATTCTGAGAAAACAAGCAAGTTCTGAGAGCCAGGGTTTTCCTAC GTAGGATGAAAAGATTCTTCTGTGTTTATAAAATATAAACAAAGATTCATGATTTATAAATGCCATTTATTTATTGATTCCTTTTTTCAAAATCCAA AAAGAAATGATGTTGGAGAAGGGAAGTTGAACGAGCATAGTCCAAAAAGCTCCTGGGGCGTCCAGGCCGCGCCCTTTCCCCGACGCCCACCCAACCC CAAGCCAGCCCGGCCGCTCCACCAGCATCACCTGCCTGTTAGGAGAAGCTGCATCCAGAGGCAAACGGAGGCAAAGCTGGCTCACCTTCCGCACGCG GATTAATTTGCATCTGAAATAGGAAACAAGTGAAAGCATATGGGTTAGATGTTGCCATGTGTTTTAGATGGTTTCTTGCAAGCATGCTTGTGAAAAT GTGTTCTCGGAGTGTGTATGCCAAGAGTGCACCCATGGTACCAATCATGAATCTTTGTTTCAGGTTCAGTATTATGTAGTTGTTCGTTGGTTATACA AGTTCTTGGTCCCTCCAGAACCACCCCGGCCCCCTGCCCGTTCTTGAAATGTAGGCATCATGCATGTCAAACATGAGATGTGTGGACTGTGGCACTT GCCTGGGTCACACACGGAGGCATCCTACCCTTTTCTGGGGAAAGACACTGCCTGGGCTGACCCCGGTGGCGGCCCCAGCACCTCAGCCTGCACAGTG TCCCCCAGGTTCCGAAGAAGATGOTCCAGCAACACAGCCTGGGCCCCAGCTCGCGGGACCCGACCCCCCGTGGGCTCCCGTGTTTTCTAGGAGACTT GCCAGAGCCGGGCACATTGAGCTGTGCAACGCCGTGGGCTGCGTCCTTTGGTCCTGTCCCCGCAGCCCTGGCAGGGGGCATGCGGTCGGGCAGGGGC TGGAGGGAGGCGGGGGCTGCCCTTGGGCCACCCCTCCTAGTTTGGGAGGAGCAGATTTTTGCAATACCAAGTATAGCCTATGGCAGAAAAAATGTCT GTAAATATGTTTTTAAAGGTGGATTTTGTTTAAAAAATCTTAATGAATGAGTCTGTTGTGTGTCATGCCAGTGAGGGACGTCAGACTCGGCTCAGCT CGGGGAGCCTTAGCCGCCCATGCACTGGGGACGCTCCGCTGCCGTGCCGCCTGCACTCCTCAGGGCAGCCTCCCCCGGCTCTACGGGGGCCGCGTGG TGCCATCCCCAGGGGGCATGACCAGATGCGTCCCAAGATGTTGATTTTTACTGTGTTTTATAAAATAGAGTGTAGTTTACAGAAAAAGACTTTAAAA GTGATCTACATGAGGAACTGTAGATGATGTATTTTTTTCATCTTTTTTGTTAACTGATTTGCAATAAAAATGATACTGATGGTGATCTGGCTTCCAC TCCCCTCTGCTCTGGCCTTTGGCTCCCTTTCTGGGAGGGAGGCAGGGCTGCTATGCTCTGAGGGAGCCAGGAGTCGAGGGCCCCTTCTGCTGGGAGA GTGACGGTGAGGCTGCCTAGTCCTGGCCCACGGGGGTGTGGGGACCACGCTGCCTCCAGGGACTCCATGGTGTCTGCAGCCTGCCTGGTCCAGGCCC TTTGTAGGGAGATGGACACACAGCAGCAAGGGGGTTGCAGCCCTATGGGAGGTGGGGCTCGTGCCTGGGGTGACACGGCTCCCAGGACACCATGCGT GAGTCTGGCCCTCCTGGCAGCTCGGGGCTCTTCTCCTCTCAGCCTCGGAGGGATGAAGGTCCCACCCAGCCATCCTGGGGACAGCCCCTCAGGGAGC TCTGCAGCAGGCAGGGGGCTGCATAGGGAGGGCCTTGAGGCAGTGGCATGACCCCTCTACGGGCTGGAGACCACAGGGAGGACTCTGGCCCCTATAG GAGGGCAAAGGGAGCTGTCGAAGCCTATGAGCAGGGCAGCATGGGTCGTGGCAGAGTCTGGAAAGTTGTGTGATCCTAAGGAACTGGCTGAGCGAGG CAGAGGCGGCCTGGTCCTGGGGCCCTGCCCCTGAATAGAGCTGCCAGCCTCACACAAGGGTGGGCCCCTTCTCTCCCCACTGCCTGGGCCTCTGCCC AGCCCCAGACCTTCAGGGCAGGCCAGTGGCTTCAAACCAGAGCGGTGGGGAGTCTGAGATCCCTCTTTGGATTGCAAAGCACTGCCTGCCCTGGGCC CAGTCTCTCCAAGGAGGGATGTGAGCCCGAGGCCTCTACTATGGCTGGGGGCTGCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNCCGGCATCACTCAGTACAGCCACAGACAGCCTGAGCGTCCACTGCCAACGACGGGTCAGCAAAAACCGTCTGCTGTGAC GGTGAACCTTAGTGTCAGCTTGGCCGGGCCATTTCGCCAAACGGAGTGTGTCTCTGAGGTGTTCTGGATGAGGTTCGCATTTGCATCCACAGCCTGG GTAAGGCAGTCCGCCCTCCCCAGTGTGGGTGGGCCCCGTGCGGTCCGCTGAGGCCCGGGGAGAACAATAGGCCGAGTGCCAGGGGTCCTCCCACCCA ACCGCTTGCACTGGACATTGGTCTTTTCCTGCCTTCAGACTTGGACTGAAAACGTGGGCTCTTCCTGGGCCTGGAGCCCACCGGCCTTCGGACTCGC AACGCCATCAGGCCTCCTGCCTGCACTGCAGACCCTGGGAACTGCAGGCCTCGAGGTCGTGTGGCCAATTCCCTGCAATAACCTCTCCAGGACTCAC GTCTTATGGGCTCCGCTTGCCGGAAGAACCCTGACGAATGCGCACGAGGGAATATGATTCCACCGTAGAAAAGGAGGCGCTGACACCCACCATGCGG ACAAGCCTTGGAAGCACGGTGCTCAGTGAAGGGTGCCGGCCGCAAGGGCCGCAGGTGCAGTGACTCCATTTCTATGGGGTGCCTGTGGTCACCGAA CCCATGGAGACAGAAAGTAGATTGATGGTTCCCAGAGCCGGGGGGAGGAGGAAAGGGGAGTGGCTGCTAAACGGCCCGGGGTTTTTTTTTGTTTTGT TTTGTTTTTATACTTTAAGTTTTAGTTTATTGTGGCACTGTTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCAACAATGATAGACTAGATT AAGAAATGTGGCACATATATACCATGGAATACTATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTGTAGGGACGTGGATGAAGACGGCCCGGG GTTTTACTTTGGAGTGACGCAAATGTTCTGGGCCCAGGGAGAGGTGGTGCGTGCACAGCCCTTCGAGTGCACTAAATGCCAATAACGCGGACACTTT TTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAATCTGGTGGCGTGATCTTGGCTCACTGCAACCTCCGCCTCTGTGTTCAA GTGATTCTCCTGCCTCAGCCTCCAAAGTAACTGGGATTACAGGCCCCTACCACCACACCCGGCTGATTTTTTTGTATTTTTAGTAGAGATTGGGTTT CACCATGTTGGCCAGGCTGGTTTCAAACTCCTGATCTCAAGTGATCCACCCGCCTCGGCCTCTTAAAGTGCTGAGGTTACAGGCGTGAGCCACTGCA CCTGGCCTAACTCGTACACTTTAAAGTGGTTAATTTTAGGTTCTGTGAGTCTCACCTCAATATGTTATTTTTTTTTTTTAATTAAAAAAAGTTTTTG AGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCCATGATAGCTTATTGCAGCCTCAACCTCCTGGGCCCAGGTGATCCTCCCACCT TGGTCTCTCTAGCAGCTGGGATTACAGGTGCACACCCCTCACCCACCCAATTTTTTTGTTATTTTTTGCAGAGATGGGGTCTCACTTTGTTGCCCA GGTTGGTCTCGAACTCCTGAGCTCATGCAGTCCTCTCCTCACCTTGGCCTCCCAGAGTGCTGGGATTACAGGTGTGGGCCATTGCGCCTGGCCACAT ATGCAACTTAAATATTTCAGTAGCCACATTAAAAAAGGTAAAAAGAAACAGCAAGTGTATATTAATACTACAGCTTAGTTAATCCAATATATCAA AAATATTATTTTAACACAACATAAAAGTGAATGAGTTTTTTTTTGTTGTTTTTTGTTTTTTGAGACAGAGTCTCCCTCTGTCACCAGGCTGGAGT GCAGTGGTGCGATCTCAGCTCACTGCAACTTCCOCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCTG CCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGATCTCTTGACCTCGTGATCGGCCAC CTCGGCCTCCCAAGTGCTGGGATTATAGGCGTAAGCCACCACGCCCGGCCGTGAATGAGATGTTTTATATTCTTTTTGTTTGTTTGTTTTTGGTAC TGTGTCTTTGAAACCCAGGATGTACAGTACACTCACAGCACCCTAGATTGGGCCTGGCCACACTTTAAAAGGTGTTCAGTATCTCCAGGAGGCTCAC GTCCAGATTCGGACTCTTCAGCAGGATGCCAAGGGGGCTCCAGACAGTTCCACCCAGCGCAGGAAAACACCAAGTGTATCTTCAGCCTGGTGACTCA CTCCACGCCGCTGCCGGCGTGAACCCCGAGTGTGGCGCTGCGTCCCTCTGGATAGAGCAAAGGAGGGTCCCAAGAGCCCGGAGGCACCAACTCATCA GGGCCCACAATCAGGCCCCCCGGCAGGCAGGGCTGCCTCCATCCAAGAGGGAAGCACGGTGCCGTAGCCCCCGGGCTGCTCCAGGGATCGACAGGCC GCCAACGGTGGCCAGTGCCTGCCCTTCGAGGCCTCCTACATCTGCCACTGCCCACCCAGCTTCCATGGCCCCACCTGCCGGCAGGATGTCAACGAGT GTGGCCAGAAGCCCGGGCTTTGCCGCCACGGAGGCACCTGCCACAACGAGGTCGGCTCCTACCGCTGCGTCTGCCGCGCCACCCGGCACTGGCCCCAA CTGCGAGCGGCCCTACGTGCCCTGCAGCCCCTCGCCCTGCCAGAACGGGGGCACCTGCCGCCCCACGGGCGACGTCACCCACGAGTGTGCCTGCCTG CCAGGCTTCACCGGCCAGAACTGTGAGGAAAATATCGACGATTGTCCAGGAAACAACTGCAAGAACGGGGGTGCCTGTGTGGACGGCGTGAACACCT ACAACTGCCGCTGCCCGCCAGAGTGGACAGGTCAGTACTGTACCGAGGATGTGGACGAGTGCCAGCTGATGCCAAATGCCTGCCAGAACGGCGGGAC CTGCCACAACACCCACGGTGGCTACAACTGCGTGTGTGTCAACGGCTGGACTGGTGAGGACTGCAGCGAGAACATTGATGACTGTGCCAGCGCCGCC TGCTTCCACGGCGCCACCTGCCATGACCGTGTGGCCTCCTTCTACTGCGAGTGTCCCCATGGCCGCACAGGTCTGCTGTGCCACCTCAACGACGCAT GCATCAGCAACCCCTGTAACGAGGGCTCCAACTGCGACACCAACCCTGTCAATGGCAAGGCCATCTGCACCTGCCCCTCGGGGTACACGGGCCCGGC CTGCAGCCAGGACGTGGATGAGTGCTCGCTGGGTGCCAACCCCTGCGAGCATGCGGGCAAGTGCATCAACACGCTGGGCTCCTTCGAGTGCCAGTGT CTGCAGGGCTACACGGGCCCCCGATGCGAGATCGACGTCAACGAGTGCGTCTCGAACCCGTGCCAGAACGAOGCCACCTGCCTGGACCAGATTGGGG AGTTCCAGTGCATCTGCATGCCCGGCTACGAGGGTGTGCACTGCGAGGTCAACACAGACGAGTGTGCCAGCAGCCCCTGCCTGCACAATGGCCGCTG CCTGGACAAGATCAATGAGTTCCAGTGCGAGTGCCCCACGGGCTTCACTGGGCATCTGTGCCAGTACGATGTGGACGAGTGTGCCAGCACCCCCTGC AAGAATGGTGCCAAGTGCCTGGACGGACCCAACACTTACACCTGTGTGTGCACGGAAGGGTACACGGGGACGCACTGCGAGGTGGACATCGATGAGT GCGACCCCGACCCCTGCCACTACGGCTCCTGCAAGGACGGCGTCGCCACCTTCACCTGCCTCTGCCGCCCAGGCTACACGGGCCACCACTGCGAGAC CAACATCAACGAGTGCTCCAGCCAGCCCTGCCGCCACGGGGGCACCTGCCAGGACCGCGACAACGCCTACCTCTGCTTCTGCCTGAAGGGGACCACA GGACCCAACTGCGAGATCAACCTGGATGACTGTGCCAGCAGCCCCTGCGACTCGGGCACCTGTCTGGACAAGATCGATGGCTACGAGTGTGCCTGTG AGCCGGGCTACACAGGGGAGCATGTGTAACATCAACATCGATGAGTGTGCGGGCAACCCCTGCCACAACGGGGGCACCTGCGAGGACGGCATCAATG GCTTCACCTGCCGCTGCCCCGAGGGCTACCACGACCCCACCTGCCTGTCTGAGGTCAATGAGTGCAACAGCAACCCCTGCGTCCACGGGGCCTGCCG GGACAGCCTCAACGGGTACAAGTGCGACTGTGACCCTGGGTGGAGTGGGACCAACTGTGACATCAACAACAATGAGTGTGAATCCAACCCTTGTGTC AACGGCGGCACCTGCAAAGACATGACCAGTGGCTACGTGTGCACCTGCCGGGAGGGCTTCAGCGGTCCCAACTGCCAGACCAACATCAACGAGTGTG CGTCCAACCCATGTCTGAACCAGGGCACGTGTATTGACGACGTTGCCGGGTACAAGTGCAACTGCCTGCTGCCCTACACAGGTGCCACGTGTGAGGT GGTGCTGGCCCCGTGTGCCCCCAGCCCCTGCAGAAACGGCGGGGAGTGCAGGCAATCCGAGGACTATGAGAGCTTCTCCTGTGTCTGCCCCACGGGC TGNNNNNNNNNGGCAGACCTGTGAGGTCGACATCAACGAGTGCGTTCTGAGCCCGTGCCGGCACGGCGCATCCTGCCAGAACACCCACGGCGGCTAC CGCTGCCACTGCCAGGCCGGCTACAGTGGGCGCAACTGCGAGACCGACATCGACGACTGCCGGCCCAGACCCGTGTCACAACGGGGGCTCCTGCACA GACGGCATCAACACGGCCTTCTGCGACTGCCTGCCCGGCTTCCGGGGCACTTTCTGTGAGGAGGACATCAACGAGTGTGCCAGTGACCCCTGCCGCA ACGGGGCCAACTGCACGGACTGCGTGGACAGCTACACGTGCACCTGCCCCGCAGGCTTCAGCGGGATCCACTGTGAGAACAACACGCCTGACTGCAC AGAGAGCTCCTGCTTCAACGGTGGCACCTGCGTGGACGGCATCAACTCGTTCACCTGCCTGTGTCCACCCGGCTTCACGGGCAGCTACTGCCAGCAC GATGTCAATGAGTGCGACTCACAGCCCTGCCTGCATGGCGGCACCTGTCAGGACGGCTGCGGCTCCTACAGGTGCACCTGCCCCCAGGGCTACACTG GCCCCAACTGCCAGAACCTTGTGCACTGGTGTGACTCCTCGCCCTGCAAGAACGGCGGCAAATGCTGGCAGACCCACACCCAGTACCGCTGCCAGTG CCCCAGCGGCTGGACCGGCCTTTACTGCGACGTGCCCAGCGTGTCCTGTGAGGTGGCTGCGCAGCGACAAGGTGTTGACGTTGCCCGCCTGTGCCAG CATGGAGGGCTCTGTGTGGACGCGGGCAACACGCACCACTGCCGCTGCCAGGCGGGCTACACAGGCAGCTACTGTGAGGACCTGGTGGACGAGTGCT CACCCAGCCCCTGCCAGAACGGGGCCACCTGCACGGACTACCTGGGCGGCTACTCCTGCAAGGTGCGTGGCCGGCTACCACGGGGTGAACTGCTCTG AGGAGATCGACGAGTGCCTCTCCCACCCCTGCCAGAACGGGGGCACCTGCCTCGACCTCCCCAACACCTACAAGTGCTCCTGCCCACGGGGCACTCA GGGTGTGCACTGTGAGATCAACGTGGACGACTGCAATCCCCCCGTTGACCCCGTGTCCCGGAGCCCCAAGTGCTTTAACAACGGCACCTGCGTGGAC CAGGTGGGCGGCTACAGCTGCACCTGCCCGCCGGGCTTCGTGGGTGAGCGCTGTGAGGGGGATGTCAACGAGTGCCTGTCCAATCCCTGCGACGCCC GTGGCACCCAGAACTGCGTGCAGCGCGTCAATGACTTCCACTGCGAGTGCCGTGCTGGTCACACCGGGCGCCGCTGCGAGTCCGTCATCAATGGCTG CAAAGGCAAGCCCTGCAAGAATGGGGGCACCTGCGCCGTGGCCTCCAACACCGCCCGCGGGTTCATCTGCAAGTGCCCTGCGGGCTTCGAGGGCGCC ACGTGTGAGAATGACGCTCGTACCTGCGGCAGCCTGCGCTGCCTCAACGGCGGCACATGCATCTCCGGCCCGCGCAGCCCCACCTGCCTGTGCCTGG GCCCCTTCACGGGCCCCGAATGCCAGTTCCCGGCCAGCAGCCCCTGCCTGGGCGGCAACCCCTGCTACAACCAGGGGACCTGTGAGCCCACATCCGA GAGCCCCTTCTACCGTTGCCTGTGCCCCGCCAAATTCAACGGGCTCTTGTGCCACATCCTGGACTACAGCTTCGGGGGTGGGGCCGGGCGCGACATC CCCCCGCCGCTGATCGAGGAGGCGTGCGAGCTGCCCGAGTGCCAGGAGGACGCGGGCAACAAGGTCTGCAGCCTGCAGTGCAACAACCACGCGTGCG GCTGGGACGGCGGTGACTGCTCCCTCAACTTCAATGACCCCTGGAAGAACTGCACGCAGTCTCTGCAGTGCTGGAAGTACTTCAGTGACGGCCACTG TGACAGCCAGTGCAACTCAGCCGCCTGCCTCTTCGACGGCTTTGACTGCCAGCGTGCGGAAGGCCAGTGCAACCCCCTGTACGACCAGTACTGCAAG GACCACTTCAGCGACGGGCACTGCGACCAGGGCTGCAACAGCGCGGAGTGCGAGTGGGACGGGCTGGACTGTGCGGAGCATGTACCCGAGAGGCTGG CGGCCGGCACGCTGGTGGTGGTGGTGCTGATGCCGCCGGAGCAGCTGCGCAACAGCTCCTTCCACTTCCTGCGGGAGCTCAGCCGCGTGCTGCACAC CAACGTGGTCTTCAAGCGTGACGCACACGGCCAGCAGATGATCTTCCCCTACTACGGCCGCGAGGAGGAGCTGCGCAAGCACCCCATCAAGCGTGCC GCCGAGGGCTGGGCCGCACCTGACGCCCTGCTGGGCCAGGTGAAGGCCTCGCTGCTCCCTGGTGGCAGCGAGGGTGGGCGGCGGCGGAGGGAGCTGG ACCCCATGGACGTCCGCGGCTCCATCGTCTACCTGGAGATTGACAACCGGCAGTGTGTGCAGGCCTCCTCGCAGTGCTTCCAGAGTGCCACCGACGT GGCCGCATTCCTGGGAGCGCTCGCCTCGCTGGGCAGCCTCIACATCCCCTACAAGATCGAGGCCGTGCAGATGAGACCGTGGAGCCGCCCCCGCCGG CGCAGCTGCACTTCATGTACGTGGCGGCGGCCGCCTTTGTGCTTCTGTTCTTCGTGGGCTGCGGGGTGCTGCTGTCCCGCAAGCGCCGGCGGCAGCA TGGCCAGCTCTGGTTCCCTGAGGGCTTCAAAGTGTCTGAGGCCAGCAAGAAGAAGCGGCGGGAGCCCCTCGGCGAGGACTCCGTGGGCCTCAAGCCC CTGAAGAACGCTTCAGACGGTGCCCTCATGGACAACCAGAATGAGTGGGGGGACGAGGACCTGGAGACCAAGAAGTTCCGGTTCGAGGAGCCCG TGGTTCTGCCTGACCTGGACGACCAGACAGACCACCGGCAGTGGACTCAGCAGCACCTGGATGCCGCTGACCTGCGCATGTCTGCCATGGCCCCCAC ACCGCCCCAGGGTGAGGTTGACGCCGACTGCATGGACGTCAATGTCCGCGGGCCTGATGGCTTCACCCCGCTCATGATCGCCTCCTGCAGCGGGGGC GGCCTGGAGACGGGCAACAGCGAGGAAGAGGAGGACGCGCCGGCCGTCATCTCCGACTTCATCTACCAGGGCGCCAGCCTGCACAACCAGACAGACC GCACGGGCGAGACCGCCTTGCACCTGGCCGCCCGCTACTCACGCTCTGATGCCGCCAAGCGCCTGCTGGAGGCOAGCGCAGATGCCAACATCCAGGA CAACATGGGCCGCACCCCGCTGCATGCGGCTGTGTCTGCCGACGCACAAGGTGTCTTCCAGATCCTGATCCGGAACCGAGCCACAGACCTGGATGCC CGCATGCATGATGGCAOGACGCCACTGATCCTGGCTGCCCGCCTGGCCGTGGAGGGCATGCTGGAGGACCTCATCAACTCACACGCCGACGTCAACG CCGTAGATGACCTGGGCAAGTCCGCCCTGCACTGGGCCGCCGCCGTGAACAATGTGGATGCCGCAGTTGTGCTCCTGAAGAACGGGGCTAACAAAGA TATGCAGAACAACAGGGAGGAGACACCCCTGTTTCTGGCCGCCCGGGAGGGCAGCTACGAGACCGCCAAGGTGCTGCTGGACCACTTTGCCAACCGG GACATCACGGATCTATGGACCGCCTGCCGCGCGACATCGCACAGGAGCGCATGCATCACGACATCGTGAGGCTGCTGGACGAGTACAACCTGGTGC GCAGCCCGCAGCTGCACGGAGCCCCGCTGGGGGGCACGCCCACCCTGTCGCCCCGCTCTGCTCGCCCAACGGCTACCTGGGCAGCCTCAAGCCCGG CGTGCAGGGCAAGAAGGTCCGCAAGCCCAGCAGCAAGGCCTGGCCTGTGGAAGCAAGGAGGCCAAGGACCTCAAGGCACGGAGGAAGAAGTCCCAG GACGGCAAGGGCTGCCTGCTGGACAGCTCCGGCATGCTCTCGCCCGTGGACTCCCTGGAGTCACCCCATGGCTACCTGTCAGACGTGGCCTCGCCGC CACTGCTGCCCTCCCCGTTCCAGCAGTCTCCGTCCGTGCCCCTCAACCACCTGCCTGGGATGCCCGACACCCACCTGGGCATCGGGCACCTGAACGT GGCGGCCAAGCCCGAGATGGCGGCGCTGGGTGGGGGCGGCCGGCTGGCCTTTGAGACTGGCCCACCTCGTCTCTCCCACCTCCTGTGGCCTCTGGC ACCAGCACCGTCCTGGGCTCCAGCAGCGGAGGGGCCCTGAATTTCACTGTGGGCGGGTCCACCAGTTTGAATGGTCAATGCGAGTGGCTGTCCCGGC TGCAGAGCGGCATGGTGCCGAACCAATACAACCCTCTGCGGGGGAGTGTGGCACCAGGCCCCCTGAGCACACAGGCCCCCCTCCCTGCAGCATGGCAT GGTAGGCCCGCTGCACGTAGCCTTGCTGCCAGCGCCCTGTCCAGATGATGAGCTACCAGGGCCTGCCCAGCACCCGGCTGGCCACCCAGCCTCAC CTGGTGCAGACCCAGCAGGTGCAGCCACAACTTACAGATGCAGCAGCAGAACCTGCAGCCAGCCAGCAAACATCCAGCAGCAGCAAAGCCTGCAGCCGC CACCACCACCACCACAGCCGCACCTTGGCGTGAGCTCAGCAGCCAGCGGCCACCGGCCGGAGCTTCCTGAGTGAGAGCCGAGCCAGGCAGACGT GCAGCCACTGGGCCCCAGCAGCCTGGCGGTGCACACTAUTCTGCCCCAGGAGAGCCCCGCCCTGCCCACGTCGCTGCCMCCTCGCTGGTCCCACCC GTGACCGCAGCCCAGTTCCTGACGCCCCCCTCGCAGCACAGCTACTCCTCGCCTGTGGACAACACCCCCAGCCACCAGCTACAGGTGCCTGAGCACC CCTTCCTCACCCCGTCCCCTGAGTCCCCTGACCAGTGGTCCAGCTCGTCCCCGCATTCCAACGTCTCCGACTGGTCCGAGGGCGTCTCCAGCCCTCC CACCAGCATGCAGTCCCAGATCGCCCGCATTCCGGAGGCCTTCAAGTAA HUMAN SEQUENCE-CODING ATGTACGTGGCGGCGGCCGCCTTTGTGCTTCTGTTCTTCGTGGGCTGCGGGGTGCTGCTGTCCCGCAAGCGCCGGCGGCAGCATGGCCAGCTCTGGT TCCCTGAGGCTTCAAAGTGTCTGAGGCCAGCAAGAAGAAGCGGCGGGAGCCCCTCGGCGAGGACTCCGTGGGCCTCAAGCCCCIGAAGAACGCTTC AGACGGTGACGACCAGACAGACCACCGGCAGTGGACTCAGCAGCACCTGGATGCCGCTGACCTGCGCATGTCTGCCATGGCCCCCACACCGCCCCAG AGGTTGACGCCGACTGCATGGACGTCAATGTCCGCGGGCCTGATGGCTTCACCCCGCTCATGATCGCCTCCTGCAGCGGGGGCGGCCTGGAGACGGG CAACAGCGAGGAAGAGGAGGACGCGCCGGCCGTCATCTCCGACTTCATCTACCAGGGCGCCAGCCTGCACAACCAGACAGACCGCACGGGCGAGACC GCCTTGCACCTGGCCGCCCGCTACTCACGCTCTGATGCCGCCAAGCGCCTGCTGGAGGCCAGCGCAGATGCCAACATCCAGGACAACATGGGCCGCA CCCCGCTGCATGCGGCTGTGTCTGCCGACGCACAAGGTGTCTTCCAGATCCTGATCCGGAACCGAGCCACAGACCTGGATGCCCGCATGCATGATGG CACGACGCCACTGATCCTGGCTGCCCGCCTGGCCGTGGAGGGCATGCTGGAGGACCTCATCAACTCACACGCCGACGTCAACGCCGTAGATGACCTG GGCAAGTCCGCCCTGCACTGGGCCGCCGCCGTGAACAATGTGGATGCCGCAGTTGTGCTCCTGAAGAACGGGGCTAACAAAGATATGCAGAACAACA GGGAGGAGACACCCCTGTTTCTGGCCGCCCGGGAGGGCAGCTACGAGACCGCCAAGGTGCTGCTGGACCACTTTGCCAACCGGGACATCACGGATCA TATGGACCGCCTGCCGCGCGACATCGCACAGGAGCGCATGCATCACGACATCQTGAGGCTGCTGGACGAGTACAACCTGGTGCGCAGCCCGCAGCTG CACGGAGCCCCGCTGGGGGGCACGCCCACCCTGTCGCCCCCGCTCTGCTCGCCCAACGGCTACCTGGGCAGCCTCAAGCCCGGCGTGCAGGGCAAGA AGGTCCGCAAGCCCAGCAGCAAAGGCCTGGCCTGTGGAAGCAAGGAGOCCAAGGACCTCAAGGCACGGAGGAAGAAGTCCCAGGACGGCAAGGGCTG CCTGCTGGACAGCTCCGGCATGCTCTCGCCCGTGGACTCCCTGGAGTCACCCCATGGOTACCTGTCAGACGTGGCCTCGCCGCCACTGCTGCCCTCC CCGTTCCAGCAGTCTCCGTCCGTGCCCCTCAACCACCTGCCTGGGATGCCCGACACCCACCTGGGCATCGGGCACCTGAACGTGGCGGCCAAGCCCG AGATGGCGGCGCTGGGTGGGGGCGGCCGGCTGGCCTTTGAGACTGGCCCACCTCGTCTCTCCCACCTGCCTGTGGCCTCTGGCACCAGCACCGTCCT GGGCTCCAGCAGCGGAGGGGCCCTGAATTTCACTGTGGGCGGGTCCACCAGTTTGAATGGTCAATGCGAGTGGCTGTCCCGGCTGCAGAGCGGCATG GTGCCGAACCAATACAACCCTCTGCGGGGGAGTGTGGCACCAGGCCCCCTGAGCACACAGGCCCCCTCCCTGCAGCATGGCATGGTAGGCCCGCTGC ACAGTAGCCTTGCTGCCAGCGCCCTGTCCCAGATGATGAGCTACCAGGGCCTGCCCAGCACCCGGCTGOCCACCCAGCCTCACCTGGTGCAGACCCA GCAGGTGCAGCCACAAAACTTACAGATGCAGCAGCAGAACCTGCAGCCAGCAAACATCCAGCAGCAGCAAAGCCTGCAGCCGCCACCACCACCACCA CAGCCGCACCTTGGCGTGAGCTCAGCAGCCAGCGGCCACCTGGGCCGGAGCTTCCTGAGTGGAGAGCCGAGCCAGGCAGACGTGCAGCCACTGGGCC CCAGCAGCCTGGCGGTGCACACTATTCTGCCCCAGGAGAGCCCCGCCCTGCCCACGTCGCTGCCATCCTCGCTGGTCCCACCCGTGACCGCAGCCCA GTTCCTGACGOCCCCCTCGCAGCACAGCTACTCCTCGCCTGTGGACAACACCCCCAGCCACCAGCTACAGGTGCCTGAGCACCCCTTCCTCACCCCG TCCCCTGAGTCCCCTGACCAGTGGTCCAGCTCGTCCCCGCATTCCAACGTCTCCGACTGGTCCGAGGGCGTCTCCAGCCCTCCCACCAGCATGCAGT CCCAGATCGCCCGCATTCCGGAGGCCTTCAAGTAA 

We claim:
 1. A recombinant nucleic acid comprising a nucleotide sequence selected from the group consisting of the sequences outlined in Tables 1-10.
 2. A host cell comprising the recombinant nucleic acid of claim
 1. 3. An expression vector comprising the recombinant nucleic acid according to claim
 2. 4. A host cell comprising the expression vector of claim
 3. 5. A recombinant protein comprising an amino acid sequence encoded by a nucleic acid sequence comprising a sequence selected from the group consisting of the sequences outlined in Tables 1-10.
 6. A method of screening drug candidates comprising: a) providing a cell that expresses a carcinoma associated (CA) gene comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10 or fragment thereof; b) adding a drug candidate to said cell; and c) determining the effect of said drug candidate on the expression of said CA gene.
 7. A method according to claim 6 wherein said determining comprises comparing the level of expression in the absence of said drug candidate to the level of expression in the presence of said drug candidate.
 8. A method of screening for a bioactive agent capable of binding to an CA protein (CAP), wherein said CAP is encoded by a nucleic acid comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10, said method comprising: a) combining said CAP and a candidate bioactive agent; and b) determining the binding of said candidate agent to said CAP.
 9. A method for screening for a bioactive agent capable of modulating the activity of an CA protein (CAP), wherein said CAP is encoded by a nucleic acid comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10, said method comprising: a) combining said CAP and a candidate bioactive agent; and b) determining the effect of said candidate agent on the bioactivity of said CAP.
 10. A method of evaluating the effect of a candidate carcinoma drug comprising: a) administering said drug to a patient; b) removing a cell sample from said patient; and c) determining alterations in the expression or activation of a gene comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10.
 11. A method of diagnosing carcinoma comprising: a) determining the expression of one or more genes comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10, in a first tissue type of a first individual; and b) comparing said expression of said gene(s) from a second normal tissue type from said first individual or a second unaffected individual; wherein a difference in said expression indicates that the first individual has carcinoma.
 12. A method for inhibiting the activity of a CA protein (CAP), wherein said CAP is encoded by a nucleic acid comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10, said method comprising binding an inhibitor to said CAP.
 13. A method of treating carcinomas comprising administering to a patient an inhibitor of an CA protein (CAP), wherein said CAP is encoded by a nucleic acid comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10.
 14. A method of neutralizing the effect of an CA protein (CAP), wherein said CAP is encoded by a nucleic acid comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10, comprising contacting an agent specific for said CAP protein with said CAP protein in an amount sufficient to effect neutralization.
 15. A polypeptide which specifically binds to a protein encoded by a nucleic acid comprising a nucleic acid selected from the group consisting of the sequences outlined in Tables 1-10.
 16. A polypeptide according to claim 15 comprising an antibody which specifically binds to a protein encoded by a nucleic acid comprising a nucleic acid sequence selected from the group consisting of the sequences outlined in Tables 1-10.
 17. A biochip comprising one or more nucleic acid segments selected from the group consisting of a nucleic acid of the sequences outlined in Tables 1-10 or fragments thereof.
 18. A method of diagnosing carcinoma or a propensity to carcinoma by sequencing at least one CA gene of an individual.
 19. A method of determining CA gene copy number comprising adding an CA gene probe to a sample of genomic DNA from an individual under conditions suitable for hybridization. 